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[PMID]:29431343
[Au] Autor:Ibraev SA; Pankin YN; Koygeldinova; Otarov EZ; Zharylkasyn Z; Izdenov AK; Alekseev AV; Zhumabekova GS; Tilemisov MK
[Ti] Título:[Longitudinal sstudy of differences between functional state of the body in workers at the chrysotile asbestos plant].
[So] Source:Gig Sanit;95(10):961-5, 2016.
[Is] ISSN:0016-9900
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:There were performed biochemical and cytological studies of blood in healthy workers of chrysotile asbestos plant in order to determine the functional state of the body, depending on the length of service and working conditions. Mentioned differences between the functional state of the organism were determined in the longitudinal study, under construction on schedule time series with the test group at specified intervals (every year for 7 years surveyed, the same group of healthy workers). The differences between the indices allow one to discriminate different levels of the functional state of the organism for the workers employed at processing complex with experience of 4 and 5 years, and for the employees in the mining and transport workshop with the experience of 5 and 6 years. As a result the work experience of 5 years is considered to be an occupational hazard for workers at processing complex, and 6 years of experience - as an occupational hazard for workers of mining and transport workshop.
[Mh] Termos MeSH primário: Asbestos Serpentinas
Asbestos
Indústrias Extrativas e de Processamento/normas
Exposição Ocupacional
Medição de Risco/métodos
Local de Trabalho
[Mh] Termos MeSH secundário: Adulto
Feminino
Disparidades nos Níveis de Saúde
Seres Humanos
Cazaquistão/epidemiologia
Estudos Longitudinais
Masculino
Exposição Ocupacional/efeitos adversos
Exposição Ocupacional/análise
Exposição Ocupacional/prevenção & controle
Fatores de Risco
Fatores de Tempo
Local de Trabalho/organização & administração
Local de Trabalho/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Asbestos, Serpentine); 1332-21-4 (Asbestos)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180213
[St] Status:MEDLINE


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[PMID]:28457891
[Au] Autor:Feletto E; Schonfeld SJ; Kovalevskiy EV; Bukhtiyarov IV; Kashanskiy SV; Moissonnier M; Straif K; Schüz J; Kromhout H
[Ad] Endereço:Section of Environment and Radiation, International Agency for Research on Cancer, Lyon, France. Electronic address: felettoe@fellows.iarc.fr.
[Ti] Título:A comparison of parallel dust and fibre measurements of airborne chrysotile asbestos in a large mine and processing factories in the Russian Federation.
[So] Source:Int J Hyg Environ Health;220(5):857-868, 2017 07.
[Is] ISSN:1618-131X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Historic dust concentrations are available in a large-scale cohort study of workers in a chrysotile mine and processing factories in Asbest, Russian Federation. Parallel dust (gravimetric) and fibre (phase-contrast optical microscopy) concentrations collected in 1995, 2007 and 2013/14 were used to determine if dust to fibre conversion factors can be estimated. MATERIALS/SUBJECTS AND METHODS: Daily medians of multiple parallel dust and fibre concentrations by sampling points were used to derive fibre to dust ratios. Applying linear mixed models, we estimated best linear unbiased predictions for the fibre to dust ratios. RESULTS AND DISCUSSION: A total of 620 daily median fibre to dust ratios were derived. In the factories, modelled ratios varied by unit, increasing along the stages of asbestos enrichment as expected. In the mine, ratios were higher in winter compared to summer. Overall, the ratios showed a strong negative dependency on dust concentration. CONCLUSIONS: Our study shows that dust to fibre conversion is possible by unit but extrapolations are needed. The patterns for exposure by dust and fibre will be similar but estimated fibre levels will show less contrast due to the conversion factor being smaller at higher dust concentrations.
[Mh] Termos MeSH primário: Poluentes Ocupacionais do Ar/análise
Asbestos Serpentinas/análise
Poeira/análise
Monitoramento Ambiental/métodos
[Mh] Termos MeSH secundário: Mineração
Federação Russa
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., INTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Air Pollutants, Occupational); 0 (Asbestos, Serpentine); 0 (Dust)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:28935666
[Au] Autor:Marsh GM; Riordan AS; Keeton KA; Benson SM
[Ad] Endereço:Center for Occupational Biostatistics and Epidemiology and Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
[Ti] Título:Non-occupational exposure to asbestos and risk of pleural mesothelioma: review and meta-analysis.
[So] Source:Occup Environ Med;74(11):838-846, 2017 Nov.
[Is] ISSN:1470-7926
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To conduct an updated literature review and meta-analysis of studies of pleural malignant mesothelioma (PMM) risk among persons exposed to asbestos non-occupationally (household and neighbourhood). METHODS: We performed a literature search for articles available in the National Center for Biotechnology Information's PubMed database published between 1967 and 2016. Meta-analyses were conducted to calculate pooled PMM risk estimates, stratifying for household or neighbourhood exposure to asbestos and/or predominant asbestos fibre type (chrysotile, amphibole or mixed). RESULTS: Eighteen studies in 12 countries comprising 665 cases met the meta-analysis inclusion criteria. We identified 13 estimates of PMM risk from neighbourhood exposures, 10 from household and one from mixed exposure, and combined the estimates using random-effects models. The overall meta-relative risk (meta-RR) was 5.9 (95% CI 4.4 to 8.7). The meta-RRs for household and neighbourhood exposures were 5.4 (95% CI 2.6 to 11.2) and 6.9 (95% CI 4.2 to 11.4), respectively. We observed trends in risk in relation to fibre type for both household and neighbourhood studies. For chrysotile, mixed and amphibole fibres, respectively, meta-RRs for neighbourhood studies were 3.8 (95% CI 0.4 to 38.4), 8.4 (95% CI 4.7 to 14.9) and 21.1 (95% CI 5.3 to 84.5) and meta-RRs for household studies were 4.0 (95% CI 0.8 to 18.8), 5.3 (95% CI 1.9 to 15.0) and 21.1 (95% CI 2.8 to 156.0). CONCLUSIONS: PMM risks from non-occupational asbestos exposure are consistent with the fibre-type potency response observed in occupational settings. By relating our findings to knowledge of exposure-response relationships in occupational settings, we can better evaluate PMM risks in communities with ambient asbestos exposures from industrial or other sources.
[Mh] Termos MeSH primário: Asbestos/efeitos adversos
Exposição Ambiental/efeitos adversos
Habitação
Neoplasias Pulmonares/induzido quimicamente
Mesotelioma/induzido quimicamente
Neoplasias Pleurais/induzido quimicamente
Distribuição Espacial da População
[Mh] Termos MeSH secundário: Asbestos Serpentinas/efeitos adversos
Exposição Ambiental/análise
Feminino
Seres Humanos
Masculino
Exposição Ocupacional
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Asbestos, Serpentine); 1332-21-4 (Asbestos)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170923
[St] Status:MEDLINE
[do] DOI:10.1136/oemed-2017-104383


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[PMID]:28793318
[Au] Autor:Choi S; Jang K; Park K; Kim H
[Ad] Endereço:Occupational Lung Disease Institute, Korea Workers' Compensation and Welfare Service, Incheon, Republic of Korea.
[Ti] Título:Real-time measurement of fibers using an HY-differential mobility analyzer with an optical particle counter (KOFAM).
[So] Source:PLoS One;12(8):e0182119, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study investigated the applicability of an HY-differential mobility analyzer with an optical particle counter (HY-DMA/OPC), named as KOFAM, for counting fibrous matters in real time. Fibers separated from particles by the HY-DMA were counted with an OPC. To assess the KOFAM performance, the proposed method and the conventional gold standard phase contrast microscopy (PCM) method were compared in terms of variables such as recovery, relative difference, coefficient of determination, and conformity. The optimal sheath-to-aerosol (outlet) flow ratio of the internal flow in the HY-DMA was determined to be 1.6:1. In terms of recovery of the HY-DMA, the highest recovery was obtained at a voltage of 500 V regardless of which type of asbestos was tested. The recovery rate for serpentine was 45.5% and that for amphibole was 34.9%. The coefficients of determination of serpentine (R2 = 0.89) and amphibole (R2 = 0.87) were highly correlated. With respect to the coefficient of variation (CV), the KOFAM demonstrated superior performance over the M7400AD and F-1 methods and showed almost no difference from the PCM method (KOFAM: 22.5%, M7400AD: 32.4%, F-1: 88.8%, and PCM: 21.9%). There was no statistically significant difference between concentration measurements of the KOFAM and PCM analyses. Accordingly, it was concluded that the KOFAM can be used as a superior alternative to conventional fiber measurement methods. The preliminary results support the use of the KOFAM for constant measurement of airborne asbestos concentrations in real time.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/análise
Asbestos Serpentinas/análise
Exposição Ambiental/análise
Monitoramento Ambiental/métodos
Material Particulado/análise
[Mh] Termos MeSH secundário: Monitoramento Ambiental/instrumentação
Exposição por Inalação/análise
Microscopia de Contraste de Fase
Tamanho da Partícula
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Asbestos, Serpentine); 0 (Particulate Matter)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171003
[Lr] Data última revisão:
171003
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182119


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[PMID]:28727529
[Au] Autor:Rosner D; Markowitz G
[Ad] Endereço:David Rosner is with the Center for the History and Ethics of Public Health, Department of Sociomedical Sciences, Mailman School of Public Health, and the Department of History, Columbia University, New York, NY. Gerald Markowitz is with the Department of Interdisciplinary Studies, John Jay College, and the Department of History, Graduate Center, both of the City University of New York, New York, NY.
[Ti] Título:"Ain't Necessarily So!": The Brake Industry's Impact on Asbestos Regulation in the 1970s.
[So] Source:Am J Public Health;107(9):1395-1399, 2017 Sep.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Canada is proposing a ban on asbestos, and the US Environmental Protection Agency has listed it among the first 10 materials it is investigating under the new Toxic Substances Control Act revisions. However, this effort is currently running up against enormous industry and political opposition. Here, we detail the activities in the early 1970s of the Friction Materials Standards Institute, an industry trade association, to stifle earlier attempts to regulate asbestos use in brake linings, one of the oldest and most obvious sources of asbestos exposure to mechanics, among others. (Am J Public Health. 2017: 1395-1399. doi: 10.2105/AJPH.2017.303901).
[Mh] Termos MeSH primário: Asbestos Serpentinas/toxicidade
Automóveis
Exposição Ocupacional
[Mh] Termos MeSH secundário: Poluentes Ocupacionais do Ar/toxicidade
Canadá
Seres Humanos
Indústrias
Estados Unidos
United States Environmental Protection Agency/legislação & jurisprudência
United States Environmental Protection Agency/normas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants, Occupational); 0 (Asbestos, Serpentine)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2017.303901


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[PMID]:28686889
[Au] Autor:Ma Y; Rajkumar M; Moreno A; Zhang C; Freitas H
[Ad] Endereço:Centre for Functional Ecology, Department of Life Sciences, Faculty of Sciences and Technology, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal. Electronic address: cathymaying@gmail.com.
[Ti] Título:Serpentine endophytic bacterium Pseudomonas azotoformans ASS1 accelerates phytoremediation of soil metals under drought stress.
[So] Source:Chemosphere;185:75-85, 2017 Oct.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study evaluates the potential of serpentine endophytic bacterium to foster phytoremediation efficiency of Trifolium arvense grown on multi-metal (Cu, Zn and Ni) contaminated soils under drought stress. A drought resistant endophytic bacterial strain ASS1 isolated from the leaves of Alyssum serpyllifolium grown in serpentine soils was identified as Pseudomonas azotoformans based on biochemical tests and partial 16S rRNA gene sequencing. P. azotoformans ASS1 possessed abiotic stress resistance (heavy metals, drought, salinity, antibiotics and extreme temperature) and plant growth promoting (PGP) properties (phosphate solubilization, nitrogen fixation, production of 1-aminocyclopropane-1-carboxylate deaminase, siderophore and ammonia). Inoculation of T. arvense with ASS1 considerably increased the plant biomass and leaf relative water content in both roll towel assay and pot experiments in the absence and presence of drought stress (DS). In the pot experiments, ASS1 greatly enhanced chlorophyll content, catalase, peroxidase, superoxide dismutase activities, and proline content (only in the absence of drought) in plant leaves, whereas they decreased the concentrations of malondialdehyde. Irrespective of water stress, ASS1 significantly improved accumulation, total removal, bio-concentration factor and biological accumulation coefficient of metals (Cu, Zn and Ni), while decreased translocation factors of Cu. The effective colonization and survival in the rhizosphere and tissue interior assured improved plant growth and successful metal phytoremediation under DS. These results demonstrate the potential of serpentine endophytic bacterium ASS1 for protecting plants against abiotic stresses and helping plants to thrive in semiarid ecosystems and accelerate phytoremediation process in metal polluted soils.
[Mh] Termos MeSH primário: Biodegradação Ambiental
Secas
Metais Pesados/metabolismo
Pseudomonas/fisiologia
Microbiologia do Solo
Poluentes do Solo/metabolismo
[Mh] Termos MeSH secundário: Asbestos Serpentinas
Bactérias/genética
Biomassa
Carbono-Carbono Liases
Metais Pesados/análise
Pseudomonas/genética
RNA Ribossômico 16S/genética
Rizosfera
Sideróforos
Solo
Poluentes do Solo/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Asbestos, Serpentine); 0 (Metals, Heavy); 0 (RNA, Ribosomal, 16S); 0 (Siderophores); 0 (Soil); 0 (Soil Pollutants); EC 3.5.99.7 (1-aminocyclopropane-1-carboxylate deaminase); EC 4.1.- (Carbon-Carbon Lyases)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170708
[St] Status:MEDLINE


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[PMID]:28438787
[Au] Autor:Pira E; Romano C; Donato F; Pelucchi C; Vecchia C; Boffetta P
[Ad] Endereço:Department of Public Health and Pediatric Sciences, University of Turin, Turin, Italy.
[Ti] Título:Mortality from cancer and other causes among Italian chrysotile asbestos miners.
[So] Source:Occup Environ Med;74(8):558-563, 2017 Aug.
[Is] ISSN:1470-7926
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the long-term mortality of a cohort of Italian asbestos miners. METHODS: The cohort included 1056 men employed in a chrysotile mine between 1930 and 1990, who were followed up during 1946-2014, for a total of 37 471 person-years of observation. Expected deaths and SMRs were computed using national and local (after 1980, when available) reference. RESULTS: A total of 294 (27.8%) subjects were alive and at the end of follow-up, 722 (68.4%) were dead and 40 (3.8%) were lost to follow-up. The SMR for overall mortality was 1.35 (95%CI 1.25 to 1.45). The SMR for pleural cancer, based on seven observed deaths, was 5.54 (95% CI 2.22 to 11.4) and related to time since first exposure, but not to duration of employment, cumulative exposure or time since last exposure. The SMR for lung cancer was 1.16 (95% CI 0.87 to 1.52; 53 observed deaths), with no excess among workers with cumulative exposure below 100 fibre/mL-years (SMR 0.82; 95% CI 0.44 to 1.40). CONCLUSIONS: The update of the follow-up of this cohort confirmed an increased mortality from pleural cancer mortality in miners exposed to chrysotile and a lack of significant increase in lung cancer mortality.
[Mh] Termos MeSH primário: Asbestos Serpentinas/efeitos adversos
Neoplasias Pulmonares/mortalidade
Mesotelioma/mortalidade
Doenças Profissionais/mortalidade
Exposição Ocupacional/efeitos adversos
Neoplasias Pleurais/mortalidade
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Causas de Morte
Doença Crônica/mortalidade
Estudos de Coortes
Monitoramento Ambiental
Seres Humanos
Itália/epidemiologia
Masculino
Meia-Idade
Mineração
Mortalidade
Neoplasias/mortalidade
Distribuição de Poisson
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Asbestos, Serpentine)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170802
[Lr] Data última revisão:
170802
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170426
[St] Status:MEDLINE
[do] DOI:10.1136/oemed-2016-103673


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[PMID]:28412490
[Au] Autor:Frizzi F; Masoni A; Çelikkol M; Palchetti E; Ciofi C; Chelazzi G; Santini G
[Ad] Endereço:Università degli Studi di Firenze, Dipartimento di Biologia, Via Madonna del Piano, 6, 50019, Sesto Fiorentino, Florence, Italy. Electronic address: filippo.frizzi@unifi.it.
[Ti] Título:Serpentine soils affect heavy metal tolerance but not genetic diversity in a common Mediterranean ant.
[So] Source:Chemosphere;180:326-334, 2017 Aug.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Natural habitats with serpentine soils are rich in heavy metal ions, which may significantly affect ecological communities. Exposure to metal pollutants results, for instance, in a reduction of population genetic diversity and a diffused higher tolerance towards heavy metals. In this study, we investigated whether chronic exposure to metals in serpentine soils affect accumulation patterns, tolerance towards metal pollutants, and genetic diversity in ants. In particular, we studied colonies of the common Mediterranean ant, Crematogaster scutellaris, along a contamination gradient consisting of two differently contaminated forests and a reference soil with no geogenic contamination. We first evaluated the metal content in both soil and ants' body. Then, we tested for tolerance towards metal pollutants by evaluating the mortality of ants fed with nickel (Ni) solutions of increasing concentrations. Finally, differences in genetic diversity among ants from different areas were assessed using eight microsatellite loci. Interestingly, a higher tolerance to nickel solutions was found in ants sampled in sites with intermediate levels of heavy metals. This may occur, because ants inhabiting strongly contaminated areas tend to accumulate higher amounts of contaminants. Additional ingestion of toxicants beyond the saturation threshold would lead to death. There was no difference in the genetic diversity among ant colonies sampled in different sites. This was probably the result of queen mediated gene flow during nuptial flights across uncontaminated and contaminated areas of limited geographical extent.
[Mh] Termos MeSH primário: Formigas/fisiologia
Metais Pesados/toxicidade
Poluentes do Solo/toxicidade
Solo/química
[Mh] Termos MeSH secundário: Animais
Asbestos Serpentinas
Tolerância a Medicamentos
Ecossistema
Variação Genética
Metais Pesados/análise
Níquel
Alcaloides de Triptamina e Secologanina
Microbiologia do Solo
Poluentes do Solo/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Asbestos, Serpentine); 0 (Metals, Heavy); 0 (Secologanin Tryptamine Alkaloids); 0 (Soil); 0 (Soil Pollutants); 7OV03QG267 (Nickel); B503RKE34F (serpentine (alkaloid))
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170417
[St] Status:MEDLINE


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[PMID]:28345684
[Au] Autor:Cwynar E; Swiatkowska B; Tomczyk J
[Ad] Endereço:Dolnoslaski Wojewódzki Osrodek Medycyny Pracy we Wroclawiu, Oddzial Jelenia Góra / Regional Centre of Occupational Medicine, Jelenia Góra Department, Wroclaw, Poland (Dyrektor Oddzialu / Head of the Department). womp.jg@womp.wroc.pl.
[Ti] Título:[Analysis of changes in radiographic lung image and lung ventilation disorders in workers occupationally exposed to chrysotile in the past].
[Ti] Título:Analiza zmian w obrazie radiologicznym pluc i zaburzen czynnosci wentylacyjnej pluc u pracowników zawodowo narazonych na azbest chryzotylowy w przeszlosci..
[So] Source:Med Pr;68(2):247-258, 2017 Mar 24.
[Is] ISSN:0465-5893
[Cp] País de publicação:Poland
[La] Idioma:pol
[Ab] Resumo:BACKGROUND: The adverse health effects of occupational exposure to asbestos dust may occur several years after first exposure. The objective of the study was to assess the relationship between lesions in the respiratory system and the factors contributing to occupational exposure to asbestos described in the first medical examination as well as to analyze the factors responsible for the progression of these changes in further medical tests. MATERIAL AND METHODS: The study group comprised 591 former workers of asbestos processing plant "Gambit" in Lubawka. The results of medical examinations carried out in 2001-2012 were assessed. Statistical inference was performed based on bilateral significance tests at the 0.05 level of significance. RESULTS: A higher risk of interstitial lung changes along with an increase in the cumulative concentration of asbestos was indicated; for the employees with the highest exposure, the adjusted odds ratio (OR) was 1.63 (95% confidence interval (CI): 0.99-2.71), while for changes with the severity degree qualifying for asbestosis diagnosis, the risk was significantly increased, over fivefold higher, compared to subjects employed in the lowest exposure. The analysis of the relationship between the progression of interstitial changes and the exposure to asbestos dust showed a fourfold higher risk of the progression in workers employed in the highest exposure. Mean values of FEV1 (forced expiratory volume in 1 s), FVC (forced vital capacity), FEV1/FVC (forced expiratory volume in 1 s to forced vital capacity) were significantly lower in the subjects working in a higher asbestos exposure. The effect of tobacco smoking on the occurrence of interstitial lung changes and their progression was also confirmed. CONCLUSIONS: The results of prophylactic medical examinations of the health status of workers formerly employed in the plants using chrysotile indicate the importance andthe need for a long-term clinical follow-up and the promotion of anti-smoking prevention in this group of former employees. Med Pr 2017;68(2):247-258.
[Mh] Termos MeSH primário: Asbestos Serpentinas/efeitos adversos
Asbestose/patologia
Pulmão/patologia
Exposição Ocupacional/efeitos adversos
Ventilação Pulmonar
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Asbestose/diagnóstico por imagem
Asbestose/epidemiologia
Asbestose/fisiopatologia
Poeira
Feminino
Seres Humanos
Pulmão/diagnóstico por imagem
Pulmão/fisiopatologia
Masculino
Meia-Idade
Polônia
Radiografia Torácica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Asbestos, Serpentine); 0 (Dust)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170328
[St] Status:MEDLINE


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[PMID]:27680005
[Au] Autor:Godoi RHM; Gonçalves SJ; Sayama C; Polezer G; Reis Neto JM; Alföldy B; Van Grieken R; Riedi CA; Yamamoto CI; Godoi AFL; Bencs L
[Ad] Endereço:Department of Environmental Engineering, Federal University of Paraná/UFPR, Curitiba, Paraná, Brazil.
[Ti] Título:Health implications of atmospheric aerosols from asbestos-bearing road pavements traditionally used in Southern Brazil.
[So] Source:Environ Sci Pollut Res Int;23(24):25180-25190, 2016 Dec.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Serpentine and amphibole asbestos occur naturally in certain geologic settings worldwide, most commonly in association with ultramafic rocks, along associated faults. Ultramafic rocks have been used in Piên County, Southern Brazil for decades for the purpose of road paving in rural and urban areas, but without the awareness of their adverse environmental and health impact. The aim of this study was the chemical characterization of aerosols re-suspended in two rural roads of Piên, paved with ultramafic rocks and to estimate the pulmonary deposition of asbestos aerosols. Bulk aerosol samples were analyzed by means of X-ray fluorescence spectrometry and X-ray diffraction analysis, in order to characterize elemental composition and crystallinity. Single-particle compositions of aerosols were analyzed by computer-controlled electron-probe microanalysis, indicating the presence of a few percentages of serpentine and amphibole. Given the chemical composition and size distribution of aerosol particles, the deposition efficiency of chrysotile, a sub-group of serpentine, in two principal segments of the human respiratory system was estimated using a lung deposition model. As an important finding, almost half of the inhaled particles were calculated to be deposited in the respiratory system. Asbestos depositions were significant (∼25 %) in the lower airways, even though the selected breathing conditions (rest situation, nose breathing) implied the lowest rate of respiratory deposition. Considering the fraction of inhalable suspended chrysotile near local roads, and the long-term exposure of humans to these aerosols, chrysotile may represent a hazard, regarding more frequent development of lung cancer in the population of the exposed region.
[Mh] Termos MeSH primário: Amiantos Anfibólicos/análise
Asbestos Serpentinas/análise
[Mh] Termos MeSH secundário: Aerossóis
Amiantos Anfibólicos/farmacocinética
Amiantos Anfibólicos/toxicidade
Asbestos Serpentinas/farmacocinética
Asbestos Serpentinas/toxicidade
Brasil
Seres Humanos
Exposição por Inalação
Neoplasias Pulmonares
Modelos Biológicos
Sistema Respiratório/metabolismo
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aerosols); 0 (Asbestos, Amphibole); 0 (Asbestos, Serpentine)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160930
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-016-7586-0



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