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[PMID]:28985540
[Au] Autor:Wang YS; Dai JG; Wang L; Tsang DCW; Poon CS
[Ad] Endereço:Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
[Ti] Título:Influence of lead on stabilization/solidification by ordinary Portland cement and magnesium phosphate cement.
[So] Source:Chemosphere;190:90-96, 2018 Jan.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Inorganic binder-based stabilization/solidification (S/S) of Pb-contaminated soil is a commonly used remediation approach. This paper investigates the influences of soluble Pb species on the hydration process of two types of inorganic binders: ordinary Portland cement (OPC) and magnesium potassium phosphate cement (MKPC). The environmental leachability, compressive strength, and setting time of the cement products are assessed as the primary performance indicators. The mechanisms of Pb involved in the hydration process are analyzed through X-ray diffraction (XRD), hydration heat evolution, and thermogravimetric analyses. Results show that the presence of Pb imposes adverse impact on the compressive strength (decreased by 30.4%) and the final setting time (prolonged by 334.7%) of OPC, but it exerts much less influence on those of MKPC. The reduced strength and delayed setting are attributed to the retarded hydration reaction rate of OPC during the induction period. These results suggest that the OPC-based S/S of soluble Pb mainly depends on physical encapsulation by calcium-silicate-hydrate (CSH) gels. In contrast, in case of MKPC-based S/S process, chemical stabilization with residual phosphate (pyromorphite and lead phosphate precipitation) and physical fixation of cementitious struvite-K are the major mechanisms. Therefore, MKPC is a more efficient and chemically stable inorganic binder for the Pb S/S process.
[Mh] Termos MeSH primário: Materiais de Construção
Chumbo/química
Compostos de Magnésio/química
Fosfatos/química
Poluentes do Solo/química
[Mh] Termos MeSH secundário: Compostos de Cálcio
Géis/química
Minerais/química
Compostos de Potássio/química
Silicatos
Poluentes Químicos da Água/química
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Calcium Compounds); 0 (Gels); 0 (Magnesium Compounds); 0 (Minerals); 0 (Phosphates); 0 (Potassium Compounds); 0 (Silicates); 0 (Soil Pollutants); 0 (Water Pollutants, Chemical); 12190-77-1 (pyromorphite); 2P299V784P (Lead); 453COF7817 (magnesium phosphate); 62I1T06190 (lead phosphate); B7862WZ632 (potassium phosphate); S4255P4G5M (calcium silicate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171007
[St] Status:MEDLINE


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[PMID]:29028600
[Au] Autor:H Valido I; Padoan E; Moreno T; Querol X; Font O; Amato F
[Ad] Endereço:Institute of Environmental Assessment and Water Research (IDÆA), Spanish National Research Council (CSIC), Barcelona, Spain. Electronic address: iris.henriquez@uab.cat.
[Ti] Título:Physico-chemical characterization of playground sand dust, inhalable and bioaccessible fractions.
[So] Source:Chemosphere;190:454-462, 2018 Jan.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dust is a mixture of natural and anthropogenic particles originated from multiple sources, which can represent an hazard for human health. Playgrounds are a site of particularly concern, due to sand dust ingestion by toddlers and inhalation. In this study, 37 sands used in public playgrounds in the city of Barcelona were physico-chemically characterized also in relation to routine maintenance activities such as disinfection and sand renewal. The analyzed sands show a felsic mineralogy dominated by Na-feldspar, quartz, and, to a lesser extent, K-feldspar, with minor amounts of clay minerals, carbonates and hematite. Particle fractions below 10, 2.5 and 1 µm represent, on average, 0.65%, 0.17% and 0.07% of bulk volume, respectively, although, due to the human grinding, these initial fractions increased every year by a 18%, 5% and 2% respectively. Disinfection of sands effectively reduced only the NH concentration, among inorganic species. The average metal content was anthropogenically enriched, with respect to the upper continental crust, only for Sb and As. Both elements show high spatial variation indicating local sources such as road traffic for Sb (contributing mostly to the total concentration), and industry for As (also contributing with highly bioaccessible Sb, Cu and Zn). A clear inverse relationship between total concentrations of some elements and their leachable (Sb) and bioaccessible (Sb and Cr) fractions is observed. The most bioaccessible elements were Ca > Ni > Cu > Sr > Cd > Pb, all above the 25% of the total concentration. Bioaccessibility was higher for the carbonate-bearing particles and for the anthropic emitted metals (>50% of Ba, Cu, K, Pb and Zn).
[Mh] Termos MeSH primário: Cidades
Poeira/análise
Monitoramento Ambiental/métodos
Parques Recreativos
Material Particulado/análise
[Mh] Termos MeSH secundário: Silicatos de Alumínio/análise
Exposição Ambiental/análise
Seres Humanos
Exposição por Inalação/análise
Metais/análise
Minerais/análise
Compostos de Potássio/análise
Dióxido de Silício/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Silicates); 0 (Dust); 0 (Metals); 0 (Minerals); 0 (Particulate Matter); 0 (Potassium Compounds); 12168-80-8 (feldspar); 7631-86-9 (Silicon Dioxide)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171014
[St] Status:MEDLINE


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[PMID]:29324770
[Au] Autor:Teng W; Kang Y; Hou W; Hu H; Luo W; Wei J; Wang L; Zhang B
[Ad] Endereço:Forestry College, Guangxi University, Nanning, Guangxi, China.
[Ti] Título:Phosphorus application reduces aluminum toxicity in two Eucalyptus clones by increasing its accumulation in roots and decreasing its content in leaves.
[So] Source:PLoS One;13(1):e0190900, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Under acidic conditions, aluminum (Al) toxicity is an important factor limiting plant productivity; however, the application of phosphorus (P) might alleviate the toxic effects of Al. In this study, seedlings of two vegetatively propagated Eucalyptus clones, E. grandis × E. urophylla 'G9' and E. grandis × E. urophylla 'DH32-29'were subjected to six treatments (two levels of Al stress and three levels of P). Under excessive Al stress, root Al content was higher, whereas shoot and leaf Al contents were lower with P application than those without P application. Further, Al accumulation was higher in the roots, but lower in the shoots and leaves of G9 than in those of DH32-29. The secretion of organic acids was higher under Al stress than under no Al stress. Further, under Al stress, the roots of G9 secreted more organic acids than those of DH32-29. With an increase in P supply, Al-induced secretion of organic acids from roots decreased. Under Al stress, some enzymes, including PEPC, CS, and IDH, played important roles in organic acid biosynthesis and degradation. Thus, our results indicate that P can reduce Al toxicity via the fixation of elemental Al in roots and restriction of its transport to stems and leaves, although P application cannot promote the secretion of organic acid anions. Further, the higher Al-resistance of G9 might be attributed to the higher Al accumulation in and organic acid anion secretion from roots and the lower levels of Al in leaves.
[Mh] Termos MeSH primário: Alumínio/toxicidade
Eucalyptus/efeitos dos fármacos
Eucalyptus/metabolismo
Fósforo/farmacologia
Folhas de Planta/metabolismo
Raízes de Plantas/metabolismo
Substâncias Protetoras/farmacologia
[Mh] Termos MeSH secundário: Compostos de Alumínio/farmacologia
Biomassa
Cloretos/farmacologia
Enzimas/metabolismo
Eucalyptus/genética
Fosfatos/administração & dosagem
Fosfatos/farmacologia
Fósforo/administração & dosagem
Folhas de Planta/efeitos dos fármacos
Proteínas de Plantas/metabolismo
Raízes de Plantas/efeitos dos fármacos
Caules de Planta/efeitos dos fármacos
Caules de Planta/metabolismo
Compostos de Potássio/administração & dosagem
Compostos de Potássio/farmacologia
Substâncias Protetoras/administração & dosagem
Distribuição Aleatória
Plântulas/efeitos dos fármacos
Plântulas/metabolismo
Estresse Fisiológico/efeitos dos fármacos
Estresse Fisiológico/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aluminum Compounds); 0 (Chlorides); 0 (Enzymes); 0 (Phosphates); 0 (Plant Proteins); 0 (Potassium Compounds); 0 (Protective Agents); 27YLU75U4W (Phosphorus); 3CYT62D3GA (aluminum chloride); B7862WZ632 (potassium phosphate); CPD4NFA903 (Aluminum)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180206
[Lr] Data última revisão:
180206
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190900


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[PMID]:28448750
[Au] Autor:Garkusheva N; Matafonova G; Tsenter I; Beck S; Batoev V; Linden K
[Ad] Endereço:a Laboratory of Engineering Ecology , Baikal Institute of Nature Management, Siberian Branch of Russian Academy of Sciences , Ulan-Ude , Russia.
[Ti] Título:Simultaneous atrazine degradation and E. coli inactivation by simulated solar photo-Fenton-like process using persulfate.
[So] Source:J Environ Sci Health A Tox Hazard Subst Environ Eng;52(9):849-855, 2017 Jul 29.
[Is] ISSN:1532-4117
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This work evaluated the feasibility of a photo-Fenton-like process using persulfate (PS) and ferrous iron (Fe ) under simulated solar radiation for degrading the herbicide atrazine (ATZ, 6-Chloro-N-ethyl-N'-isopropyl-1,3,5-triazine-2,4-diamine) and inactivating E. coli. Milli Q water, lake water, and diluted wastewater effluents were spiked both simultaneously and separately with ATZ (4 mg/L) and E. coli (10 CFU/mL), and exposed to treatment. A method for determining the average irradiance throughout the water media in the UV(A+B) range of the Xe lamp emission was developed for bench-scale experiments. These values were used to calculate the UV(A+B) fluences and the solar UV(A+B) energy doses per unit of volume (Q , kJ/L). The obtained kinetic data were presented versus energy dose. Treatment of lake water at near-neutral pH was ineffective via the photo-Fenton-like process, attaining only 20% ATZ removal and 1-log reduction of E. coli. In Milli Q water and wastewater, the complete degradation of ATZ in the absence of bacteria was observed at an average energy dose of 1.5 kJ/L (60 min), while in the presence of cells the degradation efficiency was ∼60%. When ATZ was present, E. coli inactivation was also affected in Milli Q water, with 1.4-log reduction (93%) at a dose of 1.6 kJ/L (60 min), whereas in wastewater complete inactivation was achieved at a lower dose of 1.3 kJ/L (45 min). The energy requirements on a Q basis for simultaneous 90% ATZ removal and 99.99% E. coli inactivation in Milli Q water and wastewater were shown to be less than 10 kJ/L. This suggests the solar/PS/Fe system is promising for simultaneous treatment and disinfection of wastewater effluents.
[Mh] Termos MeSH primário: Atrazina/análise
Escherichia coli/efeitos dos fármacos
Peróxido de Hidrogênio/química
Ferro/química
Compostos de Potássio/química
Sulfatos/química
Luz Solar
Poluentes Químicos da Água/análise
Purificação da Água/métodos
[Mh] Termos MeSH secundário: Atrazina/efeitos da radiação
Desinfecção/métodos
Escherichia coli/efeitos da radiação
Estudos de Viabilidade
Concentração de Íons de Hidrogênio
Águas Residuais/química
Águas Residuais/microbiologia
Poluentes Químicos da Água/efeitos da radiação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fenton's reagent); 0 (Potassium Compounds); 0 (Sulfates); 0 (Waste Water); 0 (Water Pollutants, Chemical); 6B86K0MCZC (potassium persulfate); BBX060AN9V (Hydrogen Peroxide); E1UOL152H7 (Iron); QJA9M5H4IM (Atrazine)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1080/10934529.2017.1312188


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Laus, José Luiz
Texto completo SciELO Brasil
[PMID]:28902936
[Au] Autor:Claros-Chacaltana FDY; Kobashigawa KK; Padua IRM; Valdetaro GP; Aldrovani M; Laus JL
[Ad] Endereço:MSc, Fellow PhD degree, Ophthalmology Unit, Department of Veterinary Clinical Medicine and Surgery, Faculty of Agrarian and Veterinary Sciences, Universidade Esatdual de São Paulo, FCAV-UNESP, Jaboticabal-SP, Brazil. Conception and design of the study; acquisition, analysis and interpretation of dat
[Ti] Título:Corneal angiogenesis based on different protocols of alkaline cauterization in murine models.
[So] Source:Acta Cir Bras;32(8):607-616, 2017 Aug.
[Is] ISSN:1678-2674
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Purpose: : To establish and compare protocols of alkaline cauterization for inducing corneal angiogenesis in murine models. Methods: : Twenty-four adult Wistar rats were distributed into four groups (G1, G2, G3, and G4). The right eye cornea from each rat was cauterized using filter paper (3 mm), soaked in a solution of silver and potassium nitrates (3:1). Cauterization times were 10 (G1 and G4), or 20 seconds (G2 and G3). Cauterized corneas were washed with Ringer's lactate solution. The filter paper was either removed before washing (G1 and G2), or kept on the corneas (G3 and G4). Corneas were photographed at multiple time points (2, 4, 6, 8, 11, 13, and 15 days after the procedure), and neovascularization parameters were assayed. Results: : Neovascularization was observed in 66% of G1 corneas, and 100% of G2, G3, and G4 corneas. On day 15, G1 corneas showed smaller vascularized areas (12.63 ± 12.59%) compared to those in the G3 (41.95 ± 17.32%) and G4 (33 ± 11.74%) (P < 0.05) groups. Conclusions:: The silver and potassium nitrate solution effectively induced corneal angiogenesis. The G2, G3, and G4 protocols showed excellent reproducibility, and induced vascularization in 100% of corneas.
[Mh] Termos MeSH primário: Cauterização/métodos
Neovascularização da Córnea/etiologia
Modelos Animais de Doenças
Neovascularização Patológica/etiologia
Nitratos
Compostos de Potássio
Prata
[Mh] Termos MeSH secundário: Animais
Córnea/irrigação sanguínea
Córnea/cirurgia
Masculino
Ratos Wistar
Valores de Referência
Reprodutibilidade dos Testes
Fatores de Tempo
[Pt] Tipo de publicação:COMPARATIVE STUDY; EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Nitrates); 0 (Potassium Compounds); 3M4G523W1G (Silver); RU45X2JN0Z (potassium nitrate)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170914
[St] Status:MEDLINE


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[PMID]:28873450
[Au] Autor:Yokota T; Omachi K; Suico MA; Kojima H; Kamura M; Teramoto K; Kaseda S; Kuwazuru J; Shuto T; Kai H
[Ad] Endereço:Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto City, Kumamoto, Japan.
[Ti] Título:Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome.
[So] Source:PLoS One;12(9):e0183959, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A seminal study recently demonstrated that bromide (Br-) has a critical function in the assembly of type IV collagen in basement membrane (BM), and suggested that Br- supplementation has therapeutic potential for BM diseases. Because salts of bromide (KBr and NaBr) have been used as antiepileptic drugs for several decades, repositioning of Br- for BM diseases is probable. However, the effects of Br- on glomerular basement membrane (GBM) disease such as Alport syndrome (AS) and its impact on the kidney are still unknown. In this study, we administered daily for 16 weeks 75 mg/kg or 250 mg/kg (within clinical dosage) NaBr or NaCl (control) via drinking water to 6-week-old AS mice (mouse model of X-linked AS). Treatment with 75 mg/kg NaBr had no effect on AS progression. Surprisingly, compared with 250 mg/kg NaCl, 250 mg/kg NaBr exacerbated the progressive proteinuria and increased the serum creatinine and blood urea nitrogen in AS mice. Histological analysis revealed that glomerular injury, renal inflammation and fibrosis were exacerbated in mice treated with 250 mg/kg NaBr compared with NaCl. The expressions of renal injury markers (Lcn2, Lysozyme), matrix metalloproteinase (Mmp-12), pro-inflammatory cytokines (Il-6, Il-8, Tnf-α, Il-1ß) and pro-fibrotic genes (Tgf-ß, Col1a1, α-Sma) were also exacerbated by 250 mg/kg NaBr treatment. Notably, the exacerbating effects of Br- were not observed in wild-type mice. These findings suggest that Br- supplementation needs to be carefully evaluated for real positive health benefits and for the absence of adverse side effects especially in GBM diseases such as AS.
[Mh] Termos MeSH primário: Brometos/efeitos adversos
Nefropatias/metabolismo
Cirrose Hepática
Nefrite Hereditária/metabolismo
[Mh] Termos MeSH secundário: Animais
Nitrogênio da Ureia Sanguínea
Brometos/farmacologia
Creatinina/sangue
Modelos Animais de Doenças
Membrana Basal Glomerular/patologia
Rim/metabolismo
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Nefrite/patologia
Nitrogênio/sangue
Compostos de Potássio/efeitos adversos
Compostos de Potássio/farmacologia
Proteinúria/metabolismo
Compostos de Sódio/efeitos adversos
Compostos de Sódio/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bromides); 0 (Potassium Compounds); 0 (Sodium Compounds); AYI8EX34EU (Creatinine); LC1V549NOM (sodium bromide); N762921K75 (Nitrogen); OSD78555ZM (potassium bromide)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171025
[Lr] Data última revisão:
171025
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170906
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0183959


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[PMID]:28710281
[Au] Autor:Chouchani ET; James AM; Methner C; Pell VR; Prime TA; Erickson BK; Forkink M; Lau GY; Bright TP; Menger KE; Fearnley IM; Krieg T; Murphy MP
[Ad] Endereço:From the Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02284-9168, EdwardT_Chouchani@dfci.harvard.edu.
[Ti] Título:Identification and quantification of protein -nitrosation by nitrite in the mouse heart during ischemia.
[So] Source:J Biol Chem;292(35):14486-14495, 2017 Sep 01.
[Is] ISSN:1083-351X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Nitrate (NO ) and nitrite (NO ) are known to be cardioprotective and to alter energy metabolism NO action results from its conversion to NO by salivary bacteria, but the mechanism(s) by which NO affects metabolism remains obscure. NO may act by -nitrosating protein thiols, thereby altering protein activity. But how this occurs, and the functional importance of -nitrosation sites across the mammalian proteome, remain largely uncharacterized. Here we analyzed protein thiols within mouse hearts using quantitative proteomics to determine -nitrosation site occupancy. We extended the thiol-redox proteomic technique, isotope-coded affinity tag labeling, to quantify the extent of NO -dependent -nitrosation of proteins thiols Using this approach, called SNOxICAT ( -nitrosothiol redox isotope-coded affinity tag), we found that exposure to NO under normoxic conditions or exposure to ischemia alone results in minimal -nitrosation of protein thiols. However, exposure to NO in conjunction with ischemia led to extensive -nitrosation of protein thiols across all cellular compartments. Several mitochondrial protein thiols exposed to the mitochondrial matrix were selectively -nitrosated under these conditions, potentially contributing to the beneficial effects of NO on mitochondrial metabolism. The permeability of the mitochondrial inner membrane to HNO , but not to NO , combined with the lack of -nitrosation during anoxia alone or by NO during normoxia places constraints on how -nitrosation occurs and on its mechanisms of cardioprotection and modulation of energy metabolism. Quantifying -nitrosated protein thiols now allows determination of modified cysteines across the proteome and identification of those most likely responsible for the functional consequences of NO exposure.
[Mh] Termos MeSH primário: Modelos Animais de Doenças
Mitocôndrias Cardíacas/metabolismo
Isquemia Miocárdica/metabolismo
Miocárdio/metabolismo
Nitritos/metabolismo
Processamento de Proteína Pós-Traducional
Regulação para Cima
[Mh] Termos MeSH secundário: Marcadores de Afinidade/metabolismo
Animais
Cardiotônicos/farmacologia
Permeabilidade da Membrana Celular/efeitos dos fármacos
Cisteína/metabolismo
Feminino
Coração/efeitos dos fármacos
Camundongos
Camundongos Endogâmicos C57BL
Mitocôndrias Cardíacas/efeitos dos fármacos
Mitocôndrias Hepáticas/efeitos dos fármacos
Mitocôndrias Hepáticas/metabolismo
Dilatação Mitocondrial/efeitos dos fármacos
Isquemia Miocárdica/tratamento farmacológico
Nitratos/farmacologia
Nitritos/farmacologia
Nitrosação/efeitos dos fármacos
Compostos de Potássio/farmacologia
Proteômica/métodos
Ratos Wistar
Regulação para Cima/efeitos dos fármacos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Affinity Labels); 0 (Cardiotonic Agents); 0 (Nitrates); 0 (Nitrites); 0 (Potassium Compounds); 794654G42L (potassium nitrite); K848JZ4886 (Cysteine); RU45X2JN0Z (potassium nitrate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170926
[Lr] Data última revisão:
170926
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170716
[St] Status:MEDLINE
[do] DOI:10.1074/jbc.M117.798744


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[PMID]:28686735
[Au] Autor:Gong X; Shi Z; Wang Y; Tian Y; Li W; Liu L
[Ad] Endereço:College of Energy Resources, Chengdu University of Technology, Chengdu, China.
[Ti] Título:Characteristics and origin of the relatively high-quality tight reservoir in the Silurian Xiaoheba Formation in the southeastern Sichuan Basin.
[So] Source:PLoS One;12(7):e0180980, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A mature understanding of the sandstone gas reservoir in the Xiaoheba Formation in the southeastern Sichuan Basin remains lacking. To assess the reservoir characteristics and the origin of the high-quality reservoir in the Xiaoheba Formation, this paper uses systematic field investigations, physical property analysis, thin section identification, scanning electron microscopy and electron microprobe methods. The results indicate that the Xiaoheba sandstone is an ultra-tight and ultra-low permeability reservoir, with an average porosity of 2.97% and an average permeability of 0.56×10-3 µm2. This promising reservoir is mainly distributed in the Lengshuixi and Shuangliuba regions and the latter has a relatively high-quality reservoir with an average porosity of 5.28% and average permeability of 0.53×10-3 µm2. The reservoir space comprises secondary intergranular dissolved pores, moldic pores and fractures. Microfacies, feldspar dissolution and fracture connectivity control the quality of this reservoir. The relatively weak compaction and cementation in the interbedded delta front distal bar and interdistributary bay microfacies indirectly protected the primary intergranular pores and enhanced late-stage dissolution. Late-stage potassium feldspar dissolution was controlled by the early-stage organic acid dissolution intensity and the distance from the hydrocarbon generation center. Early-stage fractures acted as pathways for organic acid migration and were therefore important factors in the formation of the reservoir. Based on these observations, the area to the west of the Shuangliuba and Lengshuixi regions has potential for gas exploration.
[Mh] Termos MeSH primário: Silicatos de Alumínio/química
Sedimentos Geológicos/análise
Campos de Petróleo e Gás
Compostos de Potássio/química
[Mh] Termos MeSH secundário: China
Permeabilidade
Porosidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Silicates); 0 (Potassium Compounds); 12168-80-8 (feldspar)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170708
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0180980


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[PMID]:28683458
[Au] Autor:Kolb L; Orbegozo D; Creteur J; Preiser JC; Vincent JL; De Backer D
[Ad] Endereço:Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
[Ti] Título:Oral Nitrate Increases Microvascular Reactivity and the Number of Visible Perfused Microvessels in Healthy Volunteers.
[So] Source:J Vasc Res;54(4):209-216, 2017.
[Is] ISSN:1423-0135
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Nitric oxide (NO) plays an important role in controlling microcirculatory function, but the effects of exogenous administration of nitrate (NO3-) on the microcirculation have not been well studied. We evaluated whether NO3- could influence the microvascular response to hypoxia in 17 healthy volunteers. We used a vascular occlusion test (VOT) to assess the response of near-infrared spectroscopy-derived indexes to hypoxic stress before and 2 h 15 min after oral administration of 800 mg potassium nitrate. We also monitored changes in the sublingual microcirculation using side-stream dark-field (SDF) video microscopy. The descending (7.3 [6.8-8.1] to 8.2 [7.9-9.8] %/min, p = 0.01) and ascending (201 [180-233] to 240 [197-285] %/min, p = 0.01) thenar oxygen saturation (StO2) slopes were significantly greater during VOT after nitrate administration than before. Sublingual SDF measurements showed increases in the total number of visible perfused vessels (i.e., from 14.1 [13.2-15.5] to 16.3 [15.4-16.7] vessels/mm, p < 0.01) and in the number of visible perfused small vessels (i.e., from 12.2 [11.5-13.7] to 14.2 [13.5-15.3] vessels/mm, p < 0.01) after nitrate administration but no changes in the microvascular flow index or in the proportion of visible perfused vessels, which were already maximal at baseline. Oral administration of nitrate therefore significantly influenced the response to a hypoxic challenge, increasing the number of visible perfused vessels and thus possibly limiting the O2 diffusion distance.
[Mh] Termos MeSH primário: Hipóxia/fisiopatologia
Isquemia/fisiopatologia
Microcirculação/efeitos dos fármacos
Microvasos/efeitos dos fármacos
Boca/irrigação sanguínea
Nitratos/administração & dosagem
Oxigênio/sangue
Compostos de Potássio/administração & dosagem
Extremidade Superior/irrigação sanguínea
[Mh] Termos MeSH secundário: Administração Oral
Adulto
Biomarcadores/sangue
Velocidade do Fluxo Sanguíneo
Difusão
Feminino
Voluntários Saudáveis
Seres Humanos
Hipóxia/sangue
Isquemia/sangue
Masculino
Microscopia de Vídeo
Microvasos/fisiopatologia
Estudos Prospectivos
Fluxo Sanguíneo Regional
Espectroscopia de Luz Próxima ao Infravermelho
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Nitrates); 0 (Potassium Compounds); RU45X2JN0Z (potassium nitrate); S88TT14065 (Oxygen)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1159/000468541


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[PMID]:28583179
[Au] Autor:Ramezani M; Rahmani F; Dehestani A
[Ad] Endereço:Department of Biology, Faculty of Sciences, Urmia University, Urmia, Iran.
[Ti] Título:Comparison between the effects of potassium phosphite and chitosan on changes in the concentration of Cucurbitacin E and on antibacterial property of Cucumis sativus.
[So] Source:BMC Complement Altern Med;17(1):295, 2017 Jun 05.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Cucurbitacins are mostly found in the members of the family Cucurbitaceae and are responsible for the bitter taste of cucumber. Pharmacological activities such as anti-bacterial and anti-tumor effects have been attributed to these structurally divers triterpens. The aim of this study was to investigate the effect of potassium phosphite (KPhi) and chitosan on Cucurbitacin E (CuE) concentration in different tissues of Cucumis sativus. The antibacterial effect of plant ethanolic extracts was also examined against E.coli PTCC 1399 and Pseudomonas aeruginosa PTCC 1430 bacterial strains. METHODS: After emergence of secondary leaves, cucumber plants were divided into 4 groups (each group consisted of 6 pots and each pot contained one plant) and different treatments performed as follows: group1. Leaves were sprayed with distilled water (Control), group 2. The leaves were solely treated with potassium phosphite (KPhi), group 3. Leaves were solely sprayed with chitosan (Chitosan), group 4. Leaves were treated with KPhi and chitosan (KPhi + chitosan). The KPhi (2 g L ) and chitosan (0.2 g L ) were applied twice every 12 h for one day. Fruits, roots and leaves were harvested 24 h later. The ethanolic extract of plant organs was used for determination of CuE concentration using HPLC approach. The antimicrobial activity was evaluated by the agar well diffusion method. The experiments were arranged in a completely randomized design (CRD) and performed in six biological replications for each treatment. Analysis of variance was performed by one-way ANOVA and Dunnette multiple comparison using SPSS. RESULTS: The highest level of CuE was recorded in fruit (2.2 g L ) of plants under concomitant applications of KPhi and chitosan. Result of antibacterial activity evaluation showed that under concomitant treatments of KPhi and chitosan, fruit extract exhibited the highest potential for activity against E. coli PTCC 1399 (with mean zone of inhibition equal to 36 mm) and Pseudomonas aeruginosa PTCC 1430 (with mean zone of inhibition equal to 33 mm). CONCLUSIONS: KPhi and chitosan can induce production of CuE compound and increase antibacterial potential of cucumber plant extract. The application of KPhi and chitosan may be considered as promising prospect in the biotechnological production of CuE.
[Mh] Termos MeSH primário: Quitosana/farmacologia
Cucumis sativus/química
Cucumis sativus/efeitos dos fármacos
Fosfitos/farmacologia
Extratos Vegetais/análise
Extratos Vegetais/farmacologia
Compostos de Potássio/farmacologia
Triterpenos/análise
Triterpenos/farmacologia
[Mh] Termos MeSH secundário: Escherichia coli/efeitos dos fármacos
Escherichia coli/crescimento & desenvolvimento
Frutas/química
Frutas/efeitos dos fármacos
Frutas/crescimento & desenvolvimento
Pseudomonas aeruginosa/efeitos dos fármacos
Pseudomonas aeruginosa/crescimento & desenvolvimento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phosphites); 0 (Plant Extracts); 0 (Potassium Compounds); 0 (Triterpenes); 13492-26-7 (potassium phosphite); 9012-76-4 (Chitosan); V8A45XYI21 (cucurbitacin E)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1808-y



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