Base de dados : MEDLINE
Pesquisa : D02.033 [Categoria DeCS]
Referências encontradas : 12275 [refinar]
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  1 / 12275 MEDLINE  
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[PMID]:29367483
[Au] Autor:Matsuura T; Ogawa A; Ohara Y; Nishina S; Nakanishi M; Gohtani S
[Ad] Endereço:Department of Applied Biological Science, Kagawa University.
[Ti] Título:Effect of Alcohols on the Phase Behavior and Emulsification of a Sucrose Fatty Acid Ester/Water/Edible Oil System.
[So] Source:J Oleo Sci;67(2):167-176, 2018 Feb 01.
[Is] ISSN:1347-3352
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The effect of alcohols (ethanol, 1-propanol, propylene glycol, glycerin, sucrose) on the phase behavior and emulsification of sucrose stearic acid ester (SSE)/water/edible vegetable oil (EVO) systems was investigated. Adding sucrose, propylene glycol, and glycerin narrowed the oil-separated two-phase region in the phase diagram of the SSE/water/EVO systems, whereas adding ethanol and 1-propanol expanded the oil-separated two-phase region. Changing the course of emulsification in the phase diagram showed that the size of the oil-droplet particle typically decreased in a system with a narrowed oil-separated region. The emulsification properties of the systems varied with respect to changes in the phase diagram. The microstructure of the systems was examined using small-angle X-ray scattering, and the ability to retain the oil in the lamellar structure of the SSEs was suggested as an important role in emulsification, because the mechanism of the systems was the same as that for the liquid crystal emulsification method.
[Mh] Termos MeSH primário: Álcoois/química
Ésteres/química
Ácidos Graxos/química
Transição de Fase
Óleos Vegetais/química
Ácidos Esteáricos/química
Sacarose/química
Água/química
[Mh] Termos MeSH secundário: Emulsões
Glicerol/química
Propilenoglicol/química
Espalhamento a Baixo Ângulo
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Emulsions); 0 (Esters); 0 (Fatty Acids); 0 (Plant Oils); 0 (Stearic Acids); 059QF0KO0R (Water); 4ELV7Z65AP (stearic acid); 57-50-1 (Sucrose); 6DC9Q167V3 (Propylene Glycol); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180126
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess17146


  2 / 12275 MEDLINE  
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[PMID]:28741644
[Au] Autor:Bieszczad B; Gilheany DG
[Ad] Endereço:Centre for Synthesis and Chemical Biology, School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland. declan.gilheany@ucd.ie.
[Ti] Título:Highly stereoselective construction of the C2 stereocentre of α-tocopherol (vitamin E) by asymmetric addition of Grignard reagents to ketones.
[So] Source:Org Biomol Chem;15(31):6483-6492, 2017 Aug 09.
[Is] ISSN:1477-0539
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Tertiary alcohol precursors of both C2 diastereoisomers of α-tocopherol were prepared in three ways by our recently reported asymmetric Grignard synthesis. The versatility of Grignard chemistry inherent in its three-way disconnection was exploited to allow the synthesis of three product grades: 77 : 23 dr (5 steps), 81 : 19 dr (5 steps) and 96 : 4 dr (7 steps, one gram scale) from readily available and abundant starting materials. The products were converted to their respective α-tocopherols in 3 steps, which allowed a definitive re-assignment of their absolute configurations.
[Mh] Termos MeSH primário: Cetonas/química
Vitaminas/síntese química
alfa-Tocoferol/síntese química
[Mh] Termos MeSH secundário: Álcoois/síntese química
Álcoois/química
Técnicas de Química Sintética
Indicadores e Reagentes
Cetonas/síntese química
Conformação Molecular
Estereoisomerismo
Vitaminas/química
alfa-Tocoferol/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Indicators and Reagents); 0 (Ketones); 0 (Vitamins); H4N855PNZ1 (alpha-Tocopherol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1039/c7ob00751e


  3 / 12275 MEDLINE  
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[PMID]:29311508
[Au] Autor:Sawama Y; Park K; Yamada T; Sajiki H
[Ad] Endereço:Laboratory of Organic Chemistry, Gifu Pharmaceutical University.
[Ti] Título:New Gateways to the Platinum Group Metal-Catalyzed Direct Deuterium-Labeling Method Utilizing Hydrogen as a Catalyst Activator.
[So] Source:Chem Pharm Bull (Tokyo);66(1):21-28, 2018.
[Is] ISSN:1347-5223
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Deuterium-labeled compounds are widely utilized in various scientific fields. We summarize the recent advances in the direct deuteration of sugar, saturated fatty acid, and arene derivatives using heterogeneous platinum group metal on carbon catalysts by our research group. Hydrogen gas is a key catalyst-activator to facilitate the present H-D exchange reactions. In this review, the direct activation method of catalysts using in situ-generated hydrogen based on the dehydrogenation of alcohols is introduced. The obtained multiple deuterium-labeled products, including bioactive compounds, are expected to contribute to the development of many scientific investigations.
[Mh] Termos MeSH primário: Deutério/química
Hidrogênio/química
Metais Pesados/química
Compostos Organometálicos/química
[Mh] Termos MeSH secundário: Álcoois/química
Catálise
Estrutura Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Alcohols); 0 (Metals, Heavy); 0 (Organometallic Compounds); 7YNJ3PO35Z (Hydrogen); AR09D82C7G (Deuterium)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1248/cpb.c17-00222


  4 / 12275 MEDLINE  
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[PMID]:29292194
[Au] Autor:Singh H; Samani D; Nambiar N; Ghate MV; Gangakhedkar RR
[Ad] Endereço:Department of Molecular Biology, National AIDS Research Institute, Pune 411026, India. Electronic address: hsingh@nariindia.org.
[Ti] Título:Prevalence of MMP-8 gene polymorphisms in HIV-infected individuals and its association with HIV-associated neurocognitive disorder.
[So] Source:Gene;646:83-90, 2018 Mar 10.
[Is] ISSN:1879-0038
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Matrix metalloproteinases (MMPs) are well-known as mediators of neuroinflammation in HIV-associated neurocognitive disorder (HAND). Increased levels of MMP-8 have been observed in the HIV-infected patients. Thus, the aim of this study was to evaluate the association of MMP-8 gene polymorphisms with modulation of HAND severity and its prevalence in HIV-infected and healthy individuals. We enrolled a total of 150 HIV-infected individuals, 50 HAND patients, 100 HIV-infected and 150 healthy individuals. MMP-8 (-799C/T, +17C/G) polymorphisms were genotyped by PCR-RFLP. MMP-8 -799TT genotype and +17G allele showed the higher risk for modulation of HAND severity (OR=2.20, P=0.19; OR=1.97, P=0.23). MMP-8 -799TT genotype differed significantly in HIV-infected individuals compared to healthy controls (20.0% vs. 11.3%, OR=2.36, P=0.048). Haplotype TG increased the risk for modulation of HAND severity (OR=2.29, P=0.29). MMP-8 -799TT and +17CG genotypes were overrepresented in the intermediate HIV disease stage compared with healthy controls (25.9% vs. 11.3%, OR=4.34, P=0.021, 14.8% vs. 9.3%, OR=2.88, P=0.11). MMP-8 +17CG genotype enhanced the risk for modulation of HAND severity in tobacco using HAND patients (OR=5.01, P=0.17). MMP-8 -799TT genotype was more frequent in tobacco using HIV-infected individuals compared with nonusers (26.3% vs. 16.7%, OR=2.08, P=0.32). MMP-8 +17CG genotype increased the risk for modulation of HAND severity in alcohol using HAND patients (OR=4.99, P=0.18). In conclusion, MMP-8 polymorphisms independently and with alcohol and tobacco usage revealed a trend of higher risk for the modulation of HAND severity. MMP-8 -799TT genotype was associated with the advancement of HIV disease.
[Mh] Termos MeSH primário: Complexo AIDS Demência/genética
Infecções por HIV/genética
Metaloproteinase 8 da Matriz/genética
Polimorfismo de Nucleotídeo Único
Regulação para Cima
[Mh] Termos MeSH secundário: Adulto
Álcoois/efeitos adversos
Estudos de Casos e Controles
Feminino
Estudos de Associação Genética
Predisposição Genética para Doença
Genótipo
Infecções por HIV/complicações
Haplótipos
Seres Humanos
Masculino
Prevalência
Regiões Promotoras Genéticas
Fatores de Risco
Índice de Gravidade de Doença
Fumar/efeitos adversos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); EC 3.4.24.34 (MMP8 protein, human); EC 3.4.24.34 (Matrix Metalloproteinase 8)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE


  5 / 12275 MEDLINE  
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[PMID]:28464284
[Au] Autor:Su H; Lin J; Wang Y; Chen Q; Wang G; Tan F
[Ad] Endereço:Chongqing Institute of Green and Interligent Technology, Chinese Academy of Science, 266, Fangzheng Avenue, Shuitu High-Tech Park, Beibei, Chongqing 400714, P. R. China.
[Ti] Título:Engineering Brevibacterium flavum for the production of renewable bioenergy: C4-C5 advanced alcohols.
[So] Source:Biotechnol Bioeng;114(9):1946-1958, 2017 09.
[Is] ISSN:1097-0290
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Biosynthesis of advanced biofuels by engineered non-natural microorganisms has been proposed to be the most promising approach for the replacement of dwindling fossil fuel resources. Brevibacterium flavum (Bf) is a model brevibacterium aerobe which lacks basic and applied research that could enable this species to produce biofuels. There are no reports regarding engineering this microorganism to produce advanced alcohols before. Here, for the first time, we developed the bacterium as a novel biosynthetic platform for advanced alcohols production via the mutagenesis and engineering to produce 2-ketoacids derived alcohols. In order to enhance the strain's capability of producing advanced alcohols, we preferentially improved intrinsic metabolism ability of the strain to obtain improved expression host (IEH) via generating mutagenesis libraries by whole cell mutagenesis (WCM). The IEH was determined via screening out the mutant strain with the highest production of branched-chain organic acids (BCOA) using high throughput screening method.. Subsequently, a novel vector system for Bf was established, and the corresponding biosynthetic pathway of directing carbon flux into the target advanced alcohols was recruited to make the bacterium possess the capability of producing advanced alcohols and further enhance the production using the IEH. Specifically, we generated bioengineered strains that were able to synthesize up to the highest 5362 and 4976 mg/L isobutanol, 1945 and 1747 mg/L 2-methyl-1-butanol (2 MB), and 785.34 and 781 mg/L 3-methyl-1-butanol (3 MB) from pure glucose and duckweed substrates, respectively. Our findings confirmed the feasibility and potential of using Bf as a novel biosynthetic platform to generate advanced biofuels with glucose and inexpensive renewable feedstock-duckweed as a fermentation substrate. Biotechnol. Bioeng. 2017;114: 1946-1958. © 2017 Wiley Periodicals, Inc.
[Mh] Termos MeSH primário: Álcoois/metabolismo
Biocombustíveis/microbiologia
Vias Biossintéticas/fisiologia
Brevibacterium flavum/fisiologia
Cetoácidos/metabolismo
Engenharia Metabólica/métodos
Energia Renovável
[Mh] Termos MeSH secundário: Álcoois/isolamento & purificação
Melhoramento Genético/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alcohols); 0 (Biofuels); 0 (Keto Acids)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE
[do] DOI:10.1002/bit.26324


  6 / 12275 MEDLINE  
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[PMID]:27770460
[Au] Autor:De Schryver E; Derycke L; Campo P; Gabriels E; Joos GF; Van Zele T; Bachert C; Hellings PW; Gevaert P
[Ad] Endereço:Upper Airways Research Laboratory, Department Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium.
[Ti] Título:Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps.
[So] Source:Clin Exp Allergy;47(2):245-253, 2017 Feb.
[Is] ISSN:1365-2222
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: An important percentage of subjects diagnosed with chronic upper airway disease report alcohol-induced worsening of their symptoms. The prevalence and characteristics of respiratory reactions provoked by alcohol-containing drinks have not been fully investigated yet. OBJECTIVE: The aim of this study was to estimate the prevalence and characteristics of alcohol hyper-responsiveness in patients with chronic airway disease and healthy controls. Furthermore, nasal inflammation was evaluated in nasal polyp patients with and without hyper-responsiveness. METHODS: We evaluated the prevalence and characteristics of alcohol-induced respiratory complaints in 1281 subjects. Chronic rhinosinusitis with nasal polyps (CRSwNP) patients with and without NSAID exacerbated respiratory disease (NERD), chronic rhinosinusitis patients without nasal polyps (CRSsNP), allergic rhinitis (AR) patients and healthy controls were approached by means of a questionnaire. Inflammatory markers (eosinophilic cationic protein (ECP), IL-5, IgE, SAE-specific IgE, IL-17, TNFα and IFNγ) in tissue were then compared between alcohol hyper-responsive and non-hyper-responsive CRSwNP patients. RESULTS: The highest prevalence of nasal and bronchial alcohol hyper-responsiveness was observed in patients with NERD, followed by CRSwNP, and less frequent in CRSsNP, AR and healthy controls. Alcohol hyper-responsiveness is significantly more prevalent in CRSwNP patients suffering from recurrent disease and in patients with severe symptomatology. In nasal tissue of the hyper-responsive CRSwNP group, we observed significantly higher nasal levels of the eosinophilic biomarker ECP. CONCLUSION AND CLINICAL RELEVANCE: Nasal hyper-responsiveness to alcohol is significantly more prevalent in severe eosinophilic upper airway disease.
[Mh] Termos MeSH primário: Álcoois/efeitos adversos
Pólipos Nasais/patologia
Rinite/etiologia
Rinite/patologia
Sinusite/etiologia
Sinusite/patologia
[Mh] Termos MeSH secundário: Adulto
Biomarcadores
Doença Crônica
Citocinas/metabolismo
Comportamento de Ingestão de Líquido
Feminino
Seres Humanos
Mediadores da Inflamação/metabolismo
Masculino
Meia-Idade
Pólipos Nasais/diagnóstico
Pólipos Nasais/imunologia
Pólipos Nasais/metabolismo
Prevalência
Rinite/diagnóstico
Rinite/metabolismo
Fatores de Risco
Sinusite/diagnóstico
Sinusite/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Biomarkers); 0 (Cytokines); 0 (Inflammation Mediators)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171222
[Lr] Data última revisão:
171222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE
[do] DOI:10.1111/cea.12836


  7 / 12275 MEDLINE  
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[PMID]:28873578
[Au] Autor:Sánchez AH; López-López A; Cortés-Delgado A; Beato VM; Medina E; de Castro A; Montaño A
[Ad] Endereço:Food Biotechnology Department, Instituto de la Grasa-CSIC, Pablo Olavide University Campus, Building 46, Utrera Road, km 1, 41013 Seville, Spain. Electronic address: ahiginio@ig.csic.es.
[Ti] Título:Effect of post-fermentation and packing stages on the volatile composition of Spanish-style green table olives.
[So] Source:Food Chem;239:343-353, 2018 Jan 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The volatile profile of Spanish-style green table olives after fermentation and the changes in volatile compounds that occurred as a result of the post-fermentation and subsequent packing stage were explored by solid phase micro-extraction (SPME) and gas chromatography coupled to mass spectrometry (GC-MS). Three olive cultivars (Manzanilla, Gordal, and Hojiblanca) were processed and olive samples were taken at three different times throughout the elaboration: after fermentation, after post-fermentation, and after packing. A total of 132 volatile compounds were identified, including 10 phenols, 25 alcohols, 11 acids, 39 esters, 8 hydrocarbons, 14 carbonyl compounds, 17 terpenes, and 6 other compounds. A varying number of compounds from each chemical family underwent significant changes because of the post-fermentation and packing stages. Among them, some typical reaction products of lipid oxidation (e.g. (E)-2-decenal and (E,E)-2,4-decadienal) increased with the post-fermentation in Manzanilla cultivar, and also as a result of packing in all three cultivars.
[Mh] Termos MeSH primário: Olea
[Mh] Termos MeSH secundário: Álcoois
Aldeídos
Fermentação
Cromatografia Gasosa-Espectrometria de Massas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Aldehydes); 2363-88-4 (2,4-decadienal)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE


  8 / 12275 MEDLINE  
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[PMID]:29036196
[Au] Autor:Aboualizadeh E; Bumah VV; Masson-Meyers DS; Eells JT; Hirschmugl CJ; Enwemeka CS
[Ad] Endereço:Physics Department, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America.
[Ti] Título:Understanding the antimicrobial activity of selected disinfectants against methicillin-resistant Staphylococcus aureus (MRSA).
[So] Source:PLoS One;12(10):e0186375, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Disinfectants and biocidal products have been widely used to combat Methicillin-resistant Staphylococcus aureus (MRSA) infections in homes and healthcare environments. Although disruption of cytoplasmic membrane integrity has been documented as the main bactericidal effect of biocides, little is known about the biochemical alterations induced by these chemical agents. In this study, we used Fourier transform infrared (FT-IR) spectroscopy and chemometric tools as an alternative non-destructive technique to determine the bactericidal effects of commonly used disinfectants against MRSA USA-300. FTIR spectroscopy permits a detailed characterization of bacterial reactivity, allowing an understanding of the fundamental mechanism of action involved in the interaction between bacteria and disinfectants. The disinfectants studied were ethanol 70% (N = 5), isopropanol (N = 5), sodium hypochlorite (N = 5), triclosan (N = 5) and triclocarban (N = 5). Results showed less than 5% colony forming units growth of MRSA treated with triclocarban and no growth in the other groups. Nearly 70,000 mid-infrared spectra from the five treatments and the two control (untreated; N = 4) groups of MRSA (bacteria grown in TSB and incubated at 37°C (Control I) / at ambient temperature (Control II), for 24h) were pre-processed and analyzed using principal component analysis followed by linear discriminant analysis (PCA-LDA). Clustering of strains of MRSA belonging to five treatments and the discrimination between each treatment and two control groups in MRSA (untreated) were investigated. PCA-LDA discriminatory frequencies suggested that ethanol-treated spectra are the most similar to isopropanol-treated spectra biochemically. Also reported here are the biochemical alterations in the structure of proteins, lipid membranes, and phosphate groups of MRSA produced by sodium hypochlorite, triclosan, and triclocarban treatments. These findings provide mechanistic information involved in the interaction between MRSA strains and hygiene products; thereby demonstrating the potential of spectroscopic analysis as an objective, robust, and label-free tool for evaluating the macromolecular changes involved in disinfectant-treated MRSA.
[Mh] Termos MeSH primário: Antibacterianos/farmacologia
Desinfetantes/farmacologia
Staphylococcus aureus Resistente à Meticilina/efeitos dos fármacos
[Mh] Termos MeSH secundário: Álcoois/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Anti-Bacterial Agents); 0 (Disinfectants)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171017
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186375


  9 / 12275 MEDLINE  
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[PMID]:28985817
[Au] Autor:Grzybowski A; Brona P
[Ad] Endereço:Poznan City Hospital, Poznan, Poland; University of Warmia and Mazury, Olsztyn, Poland. Electronic address: ae.grzybowski@gmail.com.
[Ti] Título:Nutritional optic neuropathy instead of tobacco-alcohol amblyopia.
[So] Source:Can J Ophthalmol;52(5):533, 2017 10.
[Is] ISSN:1715-3360
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Ambliopia
Tabaco
[Mh] Termos MeSH secundário: Alcoolismo
Álcoois
Seres Humanos
Doenças do Nervo Óptico
Fumar
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Alcohols)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171008
[St] Status:MEDLINE


  10 / 12275 MEDLINE  
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[PMID]:28957342
[Au] Autor:Hazarika M; Borah D; Bora P; Silva AR; Das P
[Ad] Endereço:Department of Chemistry, Dibrugarh University, Dibrugarh, India.
[Ti] Título:Biogenic synthesis of palladium nanoparticles and their applications as catalyst and antimicrobial agent.
[So] Source:PLoS One;12(9):e0184936, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This paper describes a simple in-situ process of synthesizing highly dispersed palladium nanoparticles (PdNPs) using aqueous leaf extract of GarciniapedunculataRoxb as bio-reductant and starch (0.3%) as bio-stabilizer. The PdNPs are characterized by techniques like FTIR, TEM, SEM-EDX, XRD and XPS analysis. It is worthnoting thatwhen the synthesis of nanoparticles was carried out in absence of starch, agglomeration of particles has been noticed.The starch-assisted PdNPs showed excellent aqueous-phase catalytic activities for three important reactions: the Suzuki-Miyaura cross-coupling reactions of aryl halides (aryl bromides and iodides) with arylboronic acids; selective oxidations of alcohols to corresponding carbonyl compounds; and reduction of toxic Cr(VI) to nontoxic Cr(III). Our catalyst could be reused up to four cycles without much compromising with its activity. Furthermore, the material also demonstrated excellent antimicrobial and anti-biofilm activities against a novel multidrug resistant clinical bacterial isolate Cronobactersakazakii strain AMD04. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of PdNPswere found to be 0.06 and 0.12 mM respectively.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Garcinia/química
Nanopartículas Metálicas/química
Paládio/farmacologia
[Mh] Termos MeSH secundário: Álcoois/metabolismo
Bactérias/efeitos dos fármacos
Bactérias/isolamento & purificação
Biofilmes/efeitos dos fármacos
Catálise
Cromo/metabolismo
Farmacorresistência Bacteriana Múltipla/efeitos dos fármacos
Nanopartículas Metálicas/ultraestrutura
Testes de Sensibilidade Microbiana
Oxirredução
Difração de Raios X
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Anti-Infective Agents); 0R0008Q3JB (Chromium); 5TWQ1V240M (Palladium)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171018
[Lr] Data última revisão:
171018
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170929
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0184936



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