Base de dados : MEDLINE
Pesquisa : D02.033.415.110 [Categoria DeCS]
Referências encontradas : 2753 [refinar]
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  1 / 2753 MEDLINE  
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[PMID]:29329665
[Au] Autor:Wang Y; Yu YX; Luan Y; An J; Yin DG; Zhang XY
[Ad] Endereço:School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.
[Ti] Título:Bioactivation of 1-chloro-2-hydroxy-3-butene, an in vitro metabolite of 1,3-butadiene, by rat liver microsomes.
[So] Source:Chem Biol Interact;282:36-44, 2018 Feb 25.
[Is] ISSN:1872-7786
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:1-Chloro-2-hydroxy-3-butene (CHB) is an in vitro metabolite of 1,3-butadiene, a rodent/human carcinogen. To search for an approach detecting CHB in vivo, it is vital to obtain a full understanding of CHB metabolism. Previously, we demonstrated that CHB was bioactivated to 1-chloro-3-buten-2-one (CBO) by alcohol dehydrogenase. However, CHB metabolism by cytochrome P450s has not been reported. Thus, in the present study, CHB metabolism by rat liver microsomes was investigated. The results showed that CHB was converted to 1-chloro-3,4-epoxy-2-butanol (CEB) and CBO. 4-Methylpyrazole, a cytochrome P450 2E1-specific inhibitor, inhibited the formation of both CEB and CBO, while 1-benzylimidazole, a generic cytochrome P450 inhibitor, completely abolished the formation of CEB and CBO, suggesting that CHB metabolism was mediated by cytochrome P450s. Because the molecules have two chiral centers, CEB was detected as two stereoisomers, which were designated D-CEB and M-CEB, and were characterized as (2S,3R)-/(2R,3S)-CEB and (2R,3R)-/(2S,3S)-CEB, respectively. The amounts of M-CEB were more than those of D-CEB by 50-80%. The amounts of CEB and CBO increased linearly over time from 10 (or 20 min for CBO) to 50 min. CHB metabolism followed Michaelis-Menten kinetics; the K and V values were determined to be 6.4 ±â€¯0.7 mM and 0.10 ±â€¯0.01 nmol/min/mg protein for D-CEB, 4.2 ±â€¯0.5 mM and 0.16 ±â€¯0.01 nmol/min/mg protein for M-CEB, and 4.0 ±â€¯0.5 mM and 4.6 ±â€¯0.5 nmol/min/mg protein for CBO, respectively. Thus, CBO was the dominant product of CHB metabolism. Moreover, CEB was genotoxic at ≥ 50 µM as evaluated by the comet assay. Collectively, the data showed that CHB could be bioactivated to CEB and CBO by cytochrome P450s with CBO being the predominant product. Thus, the formation of CEB and CBO can be used as evidence of CHB production. The products may also play a role in toxicity of CHB.
[Mh] Termos MeSH primário: Butadienos/metabolismo
Butanóis/metabolismo
Microssomos Hepáticos/metabolismo
[Mh] Termos MeSH secundário: Animais
Carcinógenos/metabolismo
Ensaio Cometa/métodos
Sistema Enzimático do Citocromo P-450/metabolismo
Ratos
Ratos Sprague-Dawley
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butadienes); 0 (Butanols); 0 (Carcinogens); 671-56-7 (1-chloro-2-hydroxy-3-butene); 9035-51-2 (Cytochrome P-450 Enzyme System); JSD5FGP5VD (1,3-butadiene)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180114
[St] Status:MEDLINE


  2 / 2753 MEDLINE  
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[PMID]:28853155
[Au] Autor:Zhao X; Kasbi M; Chen J; Peres S; Jolicoeur M
[Ad] Endereço:Research Laboratory in Applied Metabolic Engineering, Department of Chemical Engineering, École Polytechnique de Montréal, Montréal, Québec, Canada.
[Ti] Título:A dynamic metabolic flux analysis of ABE (acetone-butanol-ethanol) fermentation by Clostridium acetobutylicum ATCC 824, with riboflavin as a by-product.
[So] Source:Biotechnol Bioeng;114(12):2907-2919, 2017 Dec.
[Is] ISSN:1097-0290
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The present study reveals that supplementing sodium acetate (NaAc) strongly stimulates riboflavin production in acetone-butanol-ethanol (ABE) fermentation by Clostridium acetobutylicum ATCC 824 with xylose as carbon source. Riboflavin production increased from undetectable concentrations to ∼0.2 g L (0.53 mM) when supplementing 60 mM NaAc. Of interest, solvents production and biomass yield were also promoted with fivefold acetone, 2.6-fold butanol, and 2.4-fold biomass adding NaAc. A kinetic metabolic model, developed to simulate ABE biosystem, with riboflavin production, revealed from a dynamic metabolic flux analysis (dMFA) simultaneous increase of riboflavin (ribA) and GTP (precursor of riboflavin) (PurM) synthesis flux rates under NaAc supplementation. The model includes 23 fluxes, 24 metabolites, and 72 kinetic parameters. It also suggested that NaAc condition has first stimulated the accumulation of intracellular metabolite intermediates during the acidogenic phase, which have then fed the solventogenic phase leading to increased ABE production. In addition, NaAc resulted in higher intracellular levels of NADH during the whole culture. Moreover, lower GTP-to-adenosine phosphates (ATP, ADP, AMP) ratio under NaAc supplemented condition suggests that GTP may have a minor role in the cell energetic metabolism compared to its contribution to riboflavin synthesis.
[Mh] Termos MeSH primário: Acetona/metabolismo
Butanóis/metabolismo
Clostridium acetobutylicum/metabolismo
Etanol/metabolismo
Análise do Fluxo Metabólico/métodos
Riboflavina/biossíntese
Acetato de Sódio/metabolismo
[Mh] Termos MeSH secundário: Acetona/isolamento & purificação
Reatores Biológicos/microbiologia
Butanóis/isolamento & purificação
Clostridium acetobutylicum/crescimento & desenvolvimento
Simulação por Computador
Meios de Cultura/metabolismo
Etanol/isolamento & purificação
Fermentação
Modelos Biológicos
Riboflavina/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 0 (Culture Media); 1364PS73AF (Acetone); 3K9958V90M (Ethanol); 4550K0SC9B (Sodium Acetate); TLM2976OFR (Riboflavin)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170831
[St] Status:MEDLINE
[do] DOI:10.1002/bit.26393


  3 / 2753 MEDLINE  
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[PMID]:28803108
[Au] Autor:Xin F; Chen T; Jiang Y; Lu J; Dong W; Zhang W; Ma J; Zhang M; Jiang M
[Ad] Endereço:State Key Laboratory of Materials-Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, PR China; Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing 211816, PR China
[Ti] Título:Enhanced biobutanol production with high yield from crude glycerol by acetone uncoupled Clostridium sp. strain CT7.
[So] Source:Bioresour Technol;244(Pt 1):575-581, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study reports a unique acetone uncoupled Clostridium species strain CT7, which shows efficient capability of glycerol utilization with high butanol ratio. Medium compositions, such as substrate concentration, micronutrients and pH show significant effects on butanol production from glycerol by strain CT7. To further maximize butanol production, fermentation conditions were optimized by using response surface methodology (RSM). Final butanol production of 16.6g/L with yield of 0.43g/g consumed glycerol was obtained, representing the highest butanol production and yield from glycerol in the batch fermentation mode. Furthermore, strain CT7 could directly convert crude glycerol to 11.8g/L of butanol without any pretreatment. Hence, strain CT7 shows immense potential for biofuels production using waste glycerol as cheap substrate.
[Mh] Termos MeSH primário: Acetona
Clostridium/metabolismo
Glicerol
[Mh] Termos MeSH secundário: 1-Butanol
Butanóis
Fermentação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 1364PS73AF (Acetone); 8PJ61P6TS3 (1-Butanol); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170814
[St] Status:MEDLINE


  4 / 2753 MEDLINE  
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[PMID]:28803105
[Au] Autor:Fernández-Naveira Á; Veiga MC; Kennes C
[Ad] Endereço:Chemical Engineering Laboratory, Faculty of Sciences and Center for Advanced Scientific Research (CICA), University of La Coruña, Rúa da Fraga 10, E-15008 La Coruña, Spain.
[Ti] Título:Glucose bioconversion profile in the syngas-metabolizing species Clostridium carboxidivorans.
[So] Source:Bioresour Technol;244(Pt 1):552-559, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Some clostridia produce alcohols (ethanol, butanol, hexanol) from gases (CO, CO , H ) and others from carbohydrates (e.g., glucose). C. carboxidivorans can metabolize both gases as well as glucose. However, its bioconversion profile on glucose had not been reported. It was observed that C. carboxidivorans does not follow a typical solventogenic stage when grown on glucose. Indeed, at pH 6.2, it produced first a broad range of acids (acetic, butyric, hexanoic, formic, and lactic acids), several of which are generally not found, under similar conditions, during gas fermentation. Medium acidification did not allow the conversion of fatty acids into solvents. Production of some alcohols from glucose was observed in C. carboxidivorans but at high pH rather than under acidic conditions, and the total concentration of those solvents was low. At high pH, formic acid was produced first and later converted to acetic acid, but organic acids were not metabolized at low pH.
[Mh] Termos MeSH primário: Clostridium
Glucose/metabolismo
[Mh] Termos MeSH secundário: 1-Butanol
Butanóis
Etanol
Fermentação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 3K9958V90M (Ethanol); 8PJ61P6TS3 (1-Butanol); IY9XDZ35W2 (Glucose)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170814
[St] Status:MEDLINE


  5 / 2753 MEDLINE  
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[PMID]:28779668
[Au] Autor:Plaza PE; Gallego-Morales LJ; Peñuela-Vásquez M; Lucas S; García-Cubero MT; Coca M
[Ad] Endereço:Departamento de Ingeniería Química y Tecnología del Medio Ambiente, Universidad de Valladolid, c/Dr. Mergelina s/n, 47011 Valladolid, Spain.
[Ti] Título:Biobutanol production from brewer's spent grain hydrolysates by Clostridium beijerinckii.
[So] Source:Bioresour Technol;244(Pt 1):166-174, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Brewer's spent grain (BSG) is a promising feedstock for ABE fermentation. Sulfuric acid pretreatment of BSG at pH 1, 121°C and different solid loadings (5-15% w/w) was investigated. Enzymatic hydrolysis and ABE fermentation by Clostridium beijerinckii DSM 6422 of non-washed and washed pretreated BSG were performed to compare monosaccharide release and butanol production. Pretreatment at 15% w/w BSG resulted in higher availability of sugars in both the enzymatic hydrolysates and pretreatment liquid, and overall yields of 75gbutanol/kg BSG and 95gABE/kg BSG were obtained. When the enzymatic hydrolysate from the washed pretreated BSG was fermented, butanol (6.0±0.5g/L) and ABE (7.4±1.0g/L) concentrations were lower compared with 7.5±0.6g/L butanol and 10.0±0.8g/L ABE from a control. The fermentation of the liquid released in the pretreatment at 15% w/w resulted in a butanol production of 6.6±0.8g/L with a total ABE of 8.6±1.3g/L after overliming.
[Mh] Termos MeSH primário: Butanóis
Clostridium beijerinckii
[Mh] Termos MeSH secundário: 1-Butanol
Fermentação
Hidrólise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 8PJ61P6TS3 (1-Butanol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170806
[St] Status:MEDLINE


  6 / 2753 MEDLINE  
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[PMID]:28734161
[Au] Autor:Shawky E; Selim DA
[Ad] Endereço:Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Egypt. Electronic address: eman.m.shawky@alexu.edu.eg.
[Ti] Título:Evaluation of the effect of extraction solvent and organ selection on the chemical profile of Astragalus spinosus using HPTLC- multivariate image analysis.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1061-1062:134-138, 2017 Sep 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The evaluation of extraction protocols for untargeted and targeted metabolomics was implemented for root and aerial organs of Astragalus spinosus in this work. The efficiency and complementarity of commonly used extraction solvents, namely petroleum ether, methylene chloride, ethyl acetate and n-butanol were considered for method evaluation using chemometric techniques in conjunction with new, simple, and fast high performance thin layer chromatography (HPTLC) method for fingerprint analysis by extracting information from a digitalized HPTLC plate using ImageJ software. A targeted approach was furtherly implemented by developing and validating an HPTLC method allowing the quantification of three saponin glycosides. The results of untargeted and targeted principle component analysis (PCA) and hierarchical cluster analysis (HCA) revealed that the apparent saponins profile seems to depend on a combined effect of matrix composition and the properties of the selected solvent for extraction, where both the biological matrix of the investigated plant organs, as well as the extraction solvent can influence the precision of metabolite abundances. Although, the aerial part is frequently discarded as waste, it is shown hereby that it has similar chemical profile compared to the medicinal part, roots, yet a different extraction solvents pattern is recognized between the two organs which can be attributed to the differences in the composition, permeability or accessibility of the sample matrix/organ tissues, rather than the chemical structures of the detected metabolites.
[Mh] Termos MeSH primário: Astrágalo (Planta)
Cromatografia Líquida de Alta Pressão/métodos
Cromatografia em Camada Delgada/métodos
Processamento de Imagem Assistida por Computador/métodos
Extratos Vegetais/química
Estruturas Vegetais/química
[Mh] Termos MeSH secundário: Astrágalo (Planta)/química
Astrágalo (Planta)/metabolismo
Butanóis
Metabolômica/métodos
Cloreto de Metileno
Petróleo
Extratos Vegetais/análise
Estruturas Vegetais/metabolismo
Análise de Componente Principal
Saponinas/análise
Saponinas/química
Solventes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 0 (Petroleum); 0 (Plant Extracts); 0 (Saponins); 0 (Solvents); 588X2YUY0A (Methylene Chloride)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170723
[St] Status:MEDLINE


  7 / 2753 MEDLINE  
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[PMID]:28708375
[Au] Autor:Silvaroli JA; Pleshinger MJ; Banerjee S; Kiser PD; Golczak M
[Ad] Endereço:Department of Pharmacology, School of Medicine, Case Western Reserve University , Cleveland, Ohio, United States.
[Ti] Título:Enzyme That Makes You Cry-Crystal Structure of Lachrymatory Factor Synthase from Allium cepa.
[So] Source:ACS Chem Biol;12(9):2296-2304, 2017 Sep 15.
[Is] ISSN:1554-8937
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The biochemical pathway that gives onions their savor is part of the chemical warfare against microbes and animals. This defense mechanism involves formation of a volatile lachrymatory factor (LF) ((Z)-propanethial S-oxide) that causes familiar eye irritation associated with onion chopping. LF is produced in a reaction catalyzed by lachrymatory factor synthase (LFS). The principles by which LFS facilitates conversion of a sulfenic acid substrate into LF have been difficult to experimentally examine owing to the inherent substrate reactivity and lability of LF. To shed light on the mechanism of LF production in the onion, we solved crystal structures of LFS in an apo-form and in complex with a substrate analogue, crotyl alcohol. The enzyme closely resembles the helix-grip fold characteristic for plant representatives of the START (star-related lipid transfer) domain-containing protein superfamily. By comparing the structures of LFS to that of the abscisic acid receptor, PYL10, a representative of the START protein superfamily, we elucidated structural adaptations underlying the catalytic activity of LFS. We also delineated the architecture of the active site, and based on the orientation of the ligand, we propose a mechanism of catalysis that involves sequential proton transfer accompanied by formation of a carbanion intermediate. These findings reconcile chemical and biochemical information regarding thioaldehyde S-oxide formation and close a long-lasting gap in understanding of the mechanism responsible for LF production in the onion.
[Mh] Termos MeSH primário: Oxirredutases Intramoleculares/química
Cebolas/enzimologia
[Mh] Termos MeSH secundário: Butanóis/metabolismo
Cristalografia por Raios X
Oxirredutases Intramoleculares/metabolismo
Simulação de Acoplamento Molecular
Cebolas/química
Cebolas/metabolismo
Conformação Proteica
Sulfóxidos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 0 (Sulfoxides); 94Z73U61UH (thiopropanal S-oxide); D7F26UNN0B (crotonyl alcohol); EC 5.3.- (Intramolecular Oxidoreductases); EC 5.3.- (lachrymatory factor synthase, Allium cepa)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171119
[Lr] Data última revisão:
171119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170715
[St] Status:MEDLINE
[do] DOI:10.1021/acschembio.7b00336


  8 / 2753 MEDLINE  
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[PMID]:28688330
[Au] Autor:Procentese A; Raganati F; Olivieri G; Russo ME; Rehmann L; Marzocchella A
[Ad] Endereço:Istituto di Ricerche sulla Combustione - Consiglio Nazionale delle Ricerche, P.le V. Tecchio 80, 80125 Napoli, Italy. Electronic address: alessandra.procentese@unina.it.
[Ti] Título:Low-energy biomass pretreatment with deep eutectic solvents for bio-butanol production.
[So] Source:Bioresour Technol;243:464-473, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Waste lettuce leaves - from the "fresh cut vegetable" industry - were pretreated with the deep eutectic solvent (DES) made of choline chloride - glycerol. Reaction time (3-16h) and the operation temperature (80-150°C) were investigated. Enzymatic glucose and xylose yields of 94.9% and 75.0%, respectively were obtained when the biomass was pretreated at 150°C for 16h. Sugars contained in the biomass hydrolysate were fermented in batch cultures of Clostridium acetobutylicum DSMZ 792. The energy consumption and the energy efficiency related to the DES pretreatment were calculated and compared to the most common lignocellulosic pretreatment processes reported in the literature. The DES pretreatment process was characterized by lower energy required (about 28% decrease and 72% decrease) than the NAOH pretreatment and steam explosion process respectively. The Net Energy Ratio (NER) value related to butanol production via DES biomass pretreatment was assessed.
[Mh] Termos MeSH primário: Butanóis
Clostridium acetobutylicum
[Mh] Termos MeSH secundário: Biomassa
Hidrólise
Solventes
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 0 (Solvents)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170709
[St] Status:MEDLINE


  9 / 2753 MEDLINE  
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[PMID]:28671683
[Au] Autor:Opgenorth PH; Korman TP; Iancu L; Bowie JU
[Ad] Endereço:Department of Chemistry and Biochemistry, UCLA-DOE Institute for Genomics and Proteomics, Molecular Biology Institute, University of California, Los Angeles, Los Angeles, California, USA.
[Ti] Título:A molecular rheostat maintains ATP levels to drive a synthetic biochemistry system.
[So] Source:Nat Chem Biol;13(9):938-942, 2017 Sep.
[Is] ISSN:1552-4469
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Synthetic biochemistry seeks to engineer complex metabolic pathways for chemical conversions outside the constraints of the cell. Establishment of effective and flexible cell-free systems requires the development of simple systems to replace the intricate regulatory mechanisms that exist in cells for maintaining high-energy cofactor balance. Here we describe a simple rheostat that regulates ATP levels by controlling the flow down either an ATP-generating or non-ATP-generating pathway according to the free-phosphate concentration. We implemented this concept for the production of isobutanol from glucose. The rheostat maintains adequate ATP concentrations even in the presence of ATPase contamination. The final system including the rheostat produced 24.1 ± 1.8 g/L of isobutanol from glucose in 91% theoretical yield with an initial productivity of 1.3 g/L/h. The molecular rheostat concept can be used in the design of continuously operating, self-sustaining synthetic biochemistry systems.
[Mh] Termos MeSH primário: Trifosfato de Adenosina/metabolismo
Butanóis/metabolismo
Engenharia Metabólica
[Mh] Termos MeSH secundário: Sistema Livre de Células
Modelos Moleculares
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 56F9Z98TEM (isobutyl alcohol); 8L70Q75FXE (Adenosine Triphosphate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170908
[Lr] Data última revisão:
170908
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170704
[St] Status:MEDLINE
[do] DOI:10.1038/nchembio.2418


  10 / 2753 MEDLINE  
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[PMID]:28651132
[Au] Autor:Yang M; Kuittinen S; Vepsäläinen J; Zhang J; Pappinen A
[Ad] Endereço:College of Forestry, Northwest A&F University, 3 Taicheng Road, 712100 Yangling, China; School of Forest Sciences, University of Eastern Finland, P.O. Box 111, FI80101 Joensuu, Finland.
[Ti] Título:Enhanced acetone-butanol-ethanol production from lignocellulosic hydrolysates by using starchy slurry as supplement.
[So] Source:Bioresour Technol;243:126-134, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study aims to improve acetone-butanol-ethanol production from the hydrolysates of lignocellulosic material by supplementing starchy slurry as nutrients. In the fermentations of glucose, xylose and the hydrolysates of Salix schwerinii, the normal supplements such as buffer, minerals, and vitamins solutions were replaced with the barley starchy slurry. The ABE production was increased from 0.86 to 14.7g/L by supplementation of starchy slurry in the fermentation of xylose and the utilization of xylose increased from 29% to 81%. In the fermentations of hemicellulosic and enzymatic hydrolysates from S. schwerinii, the ABE yields were increased from 0 and 0.26 to 0.35 and 0.33g/g sugars, respectively. The results suggested that the starchy slurry supplied the essential nutrients for ABE fermentation. The starchy slurry as supplement could improve the ABE production from both hemicellulosic and cellulosic hydrolysate of lignocelluloses, and it is particularly helpful for enhancing the utilization of xylose from hemicelluloses.
[Mh] Termos MeSH primário: Acetona
Butanóis
Etanol
[Mh] Termos MeSH secundário: 1-Butanol
Fermentação
Lignina
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butanols); 11132-73-3 (lignocellulose); 1364PS73AF (Acetone); 3K9958V90M (Ethanol); 8PJ61P6TS3 (1-Butanol); 9005-53-2 (Lignin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170627
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde