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[PMID]:28470446
[Au] Autor:Sundaran PS; Bhaskaran A; Alex ST; Prasad T; Haritha VH; Anie Y; Kumary TV; Anil Kumar PR
[Ad] Endereço:Division of Tissue Culture, Department of Applied Biology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695 012, India.
[Ti] Título:Drug loaded microbeads entrapped electrospun mat for wound dressing application.
[So] Source:J Mater Sci Mater Med;28(6):88, 2017 Jun.
[Is] ISSN:1573-4838
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A new design of antibiotic loaded wound dressing and its initial in vitro evaluation is described. Chitosan microbeads loaded with ampicillin were sandwiched within polycaprolactone electrospun mat (MbAPPCL). The morphology was analyzed by scanning electron microscopy and surface chemistry was characterized by Fourier Transform Infrared Spectroscopy. In vitro cytotoxicity using L-929 fibroblast cells by direct contact test and elution assay revealed non-cytotoxic nature of MbAPPCL. The cell adhesion and viability analysis further confirmed the cytocompatibility of MbAPPCL as a wound dressing material. Percentage hemolysis and platelet adhesion on the mat exposed to blood substantiated the hemocompatibility. The antibiotic susceptibility test analyzed on Staphylococcus aureus by agar plate method confirmed the drug release and antimicrobial property. The proposed wound dressing model explained with ampicillin as a candidate drug has the potential to include microbeads with different antibiotics for multi drug treatment.
[Mh] Termos MeSH primário: Bandagens
Portadores de Fármacos
Microesferas
[Mh] Termos MeSH secundário: Animais
Antibacterianos/química
Antibacterianos/farmacologia
Materiais Biocompatíveis
Plaquetas
Linhagem Celular
Quitosana
Técnicas Eletroquímicas
Fibroblastos/fisiologia
Teste de Materiais
Camundongos
Penicilinas/química
Penicilinas/farmacologia
Staphylococcus aureus/efeitos dos fármacos
Estreptomicina/química
Estreptomicina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Biocompatible Materials); 0 (Drug Carriers); 0 (Penicillins); 9012-76-4 (Chitosan); Y45QSO73OB (Streptomycin)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1007/s10856-017-5893-8


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[PMID]:27778050
[Au] Autor:Sörgel F; Höhl R; Glaser R; Stelzer C; Munz M; Vormittag M; Kinzig M; Bulitta J; Landersdorfer C; Junger A; Christ M; Wilhelm M; Holzgrabe U
[Ad] Endereço:IBMP - Institut für Biomedizinische und Pharmazeutische Forschung, Paul-Ehrlich-Straße 19, 90562, Nürnberg-Heroldsberg, Deutschland. ibmp@osn.de.
[Ti] Título:[Pharmacokinetics and pharmacodynamics of antibiotics in intensive care].
[Ti] Título:Pharmakokinetik und Pharmakodynamik von Antibiotika in der Intensivmedizin..
[So] Source:Med Klin Intensivmed Notfmed;112(1):11-23, 2017 Feb.
[Is] ISSN:2193-6226
[Cp] País de publicação:Germany
[La] Idioma:ger
[Ab] Resumo:Optimized dosage regimens of antibiotics have remained obscure since their introduction. During the last two decades pharmacokinetic(PK)-pharmacodynamic(PD) relationships, originally established in animal experiments, have been increasingly used in patients. The action of betalactams is believed to be governed by the time the plasma concentration is above the minimum inhibitory concentration (MIC). Aminoglycosides act as planned when the peak concentration is a multiple of the MIC and vancomycin seems to work best when the area under the plasma vs. time curve (AUC) to MIC has a certain ratio. Clinicians should be aware that these relationships can only be an indication in which direction dosing should go. Larger studies with sufficiently high numbers of patients and particularly severely sick patients are needed to prove the concepts. In times where all antibiotics can be measured with new technologies, the introduction of therapeutic drug monitoring (TDM) is suggested for ICUs (Intensive Care Unit). The idea of a central lab for TDM of antibiotics such as PEAK (Paul Ehrlich Antibiotika Konzentrationsmessung) is supported.
[Mh] Termos MeSH primário: Antibacterianos/farmacocinética
Cuidados Críticos
[Mh] Termos MeSH secundário: Antibacterianos/uso terapêutico
Monitoramento de Medicamentos
Feminino
Meia-Vida
Seres Humanos
Unidades de Terapia Intensiva
Masculino
Espectrometria de Massas
Taxa de Depuração Metabólica/fisiologia
Testes de Sensibilidade Microbiana
Penicilinas/farmacocinética
Penicilinas/uso terapêutico
Ligação Proteica/fisiologia
Valores de Referência
Vancomicina/farmacocinética
Vancomicina/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins); 6Q205EH1VU (Vancomycin)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161026
[St] Status:MEDLINE
[do] DOI:10.1007/s00063-016-0185-5


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[PMID]:28454489
[Au] Autor:Ren J; Ni H; Kim M; Cooley KL; Valenzuela RM; Asche CV
[Ad] Endereço:a Center for Outcomes Research , University of Illinois College of Medicine at Peoria , Peoria , Illinois , USA.
[Ti] Título:Allergies, antibiotics use, and multiple sclerosis.
[So] Source:Curr Med Res Opin;33(8):1451-1456, 2017 Aug.
[Is] ISSN:1473-4877
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The associations between allergies, antibiotics use, and multiple sclerosis (MS) remain controversial and their mediating or moderating effects have not yet been examined. We aimed to assess the direct and indirect influences of allergies and antibiotics use on MS development, and their interactions. METHODS: A 1:3 matched case-control study was performed using the National Ambulatory Medical Care Survey database from 2006 to 2013 in the USA. Multiple sclerosis was identified based on the ICD-9 code (340.0) in any position. Cases were matched to their controls based on survey year, age, gender, race, payer type, region, and tobacco use. Allergy diseases and antibiotics prescriptions were extracted by ICD-9 code and drug classification code, respectively. Both generalized structural equation model and MacArthur approach were used to examine their intrinsic relationships. RESULTS: The weighted prevalence of MS was 133.7 per 100,000 visits. A total of 829 MS patients and 2441 controls were matched. Both respiratory tract allergies (OR = 0.29, 95% CI: 0.18, 0.49) and other allergies (OR = 0.38, 95% CI: 0.19, 0.77) were associated with a reduction of the risk of MS. Patients with respiratory tract allergies were more likely to use penicillin (OR = 8.73, 95% CI: 4.12, 18.53) and other antibiotics (OR = 3.77, 95% CI: 2.72, 5.21), and those with other allergies had a higher likelihood of penicillin use (OR = 4.15, 95% CI: 1.27, 13.54); however, the link between antibiotics use and MS was not confirmed although penicillin use might mediate the relationship between allergies and MS. CONCLUSIONS: The findings supported allergy as a protective factor for MS development. We also suggest antibiotics use might not be a suitable indicator of bacterial infection to investigate the cause of MS.
[Mh] Termos MeSH primário: Antibacterianos/administração & dosagem
Hipersensibilidade/epidemiologia
Esclerose Múltipla/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos de Casos e Controles
Bases de Dados Factuais
Feminino
Seres Humanos
Masculino
Meia-Idade
Esclerose Múltipla/etiologia
Penicilinas/administração & dosagem
Prevalência
Fatores de Proteção
Risco
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170430
[St] Status:MEDLINE
[do] DOI:10.1080/03007995.2017.1325575


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[PMID]:29381995
[Au] Autor:Yan Y; Wang J; Qu B; Zhang Y; Wei Y; Liu H; Wu C
[Ad] Endereço:Department of Neurology.
[Ti] Título:CXCL13 and TH1/Th2 cytokines in the serum and cerebrospinal fluid of neurosyphilis patients.
[So] Source:Medicine (Baltimore);96(47):e8850, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Neurosyphilis is a chronic infectious disease with involvement of central nervous system infection by Treponema pallidum. This study was to investigate the contents of B lymphocyte chemokine 1 (BLC-1/chemokine [C-X-C motif] ligand 13), Th1 cytokines (Interleukin [IL]-2, IL-12, and Interferon [IFN]-γ), and Th2 cytokines (IL-6 and IL-10) in serum and cerebrospinal fluid (CSF) of HIV-negative patients with neurosyphilis before and after treatment, aiming to elucidate roles of CXCL13 and Th1/Th2 cytokines in immune response to and pathogenesis of neurosyphilis.Enzyme-linked immunosorbent assay was employed to detect the contents of CXCL13, IL-2, IL-12, IFN-γ, IL-6, and IL-10 in serum and CSF of 47 HIV-negative patients with neurosyphilis, 36 syphilis patients without neurological involvement and 23 controls (noninfectious intracranial disease) before, 3 and 12 months after treatment with high dose penicillin.Results showed that there was no significant difference in blood CXCL13 content among 3 groups (P > .05); CSF CXCL13 content in neurosyphilis patients was significantly higher than in other 2 groups (P < .001), and positively related to leucocyte count, protein concentration, and IgG index. IL-6 and IL-10 contents of the serum and CSF in neurosyphilis patients were markedly higher than in other 2 groups (P < .05 or .01), but IL-2, IL-12, and IFN-γ of the serum and CSF were significantly lower than in other 2 groups (P < .05 or .01). The IL-6, IL-10, IL-2, IL-12, and IFN-γ contents of the serum and CSF were comparable between control group and syphilis group (P > .05). CSF CXCL13 content was positively related with IL-6 and IL-10 content, while negatively related to IL-12 content in neurosyphilis patients. CSF IL-6 content was negatively related with IL-12 content. In neurosyphilis patients, the CSF CXCL13 content reduced significantly at 3 and 12 months (P < .001), the CSF IL-2 and IL-12 contents increased significantly at 12 months, and CSF IL-6 contents reduced significantly at 12 months after treatment (P < .05 or .01).It is concluded that neurosyphilis patients did not have normal immune function. CXCL13 and Th1/Th2 cytokines are involved in the immune response of neurosyphilis patients. CSF CXCL13 and Th1/Th2 cytokines contents may be used for the diagnosis and evaluation of therapeutic efficacy of neurosyphilis.
[Mh] Termos MeSH primário: Quimiocina CXCL13/análise
Citocinas/análise
Neurossífilis/sangue
Neurossífilis/líquido cefalorraquidiano
[Mh] Termos MeSH secundário: Adulto
Idoso
Antibacterianos/uso terapêutico
Estudos de Casos e Controles
Ensaio de Imunoadsorção Enzimática
Feminino
Seres Humanos
Interferon gama/análise
Interleucina-10/análise
Interleucina-12/análise
Interleucina-2/análise
Interleucina-6/análise
Masculino
Meia-Idade
Neurossífilis/tratamento farmacológico
Penicilinas/uso terapêutico
Sífilis/sangue
Sífilis/líquido cefalorraquidiano
Sífilis/tratamento farmacológico
Equilíbrio Th1-Th2/efeitos dos fármacos
Adulto Jovem
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (CXCL13 protein, human); 0 (Chemokine CXCL13); 0 (Cytokines); 0 (IL10 protein, human); 0 (IL2 protein, human); 0 (IL6 protein, human); 0 (Interleukin-2); 0 (Interleukin-6); 0 (Penicillins); 130068-27-8 (Interleukin-10); 187348-17-0 (Interleukin-12); 82115-62-6 (Interferon-gamma)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008850


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[PMID]:29172367
[Au] Autor:Malamos D; Scully C
[Ti] Título:Clinical Challenges Q&A 30. Red Skin.
[So] Source:Dent Update;44(4):363, 2017 Apr.
[Is] ISSN:0305-5000
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Erupção por Droga/patologia
Dermatoses da Mão/patologia
[Mh] Termos MeSH secundário: Antibacterianos/efeitos adversos
Erupção por Droga/etiologia
Feminino
Dermatoses da Mão/etiologia
Seres Humanos
Meia-Idade
Penicilinas/efeitos adversos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:28747159
[Au] Autor:Spaltenstein M; Humbert F; Vu DL; Uçkay I; John G
[Ad] Endereço:Division of Internal Medicine, Hôpital Neuchâtelois, La Chaux-de-Fonds, Switzerland.
[Ti] Título:A case report of CT-diagnosed renal infarct secondary to syphilitic aortitis.
[So] Source:BMC Infect Dis;17(1):520, 2017 07 26.
[Is] ISSN:1471-2334
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Even though reported cases of syphilis have been increasing, cases of tertiary syphilis remain extremely rare. The majority of our knowledge with regard to complications of syphilis such as aortitis was acquired before the advent of relatively modern technologies such as CT, MRI and PET. This case report presents a rare case of syphilitic aortitis associated with a renal infarct caused by a peripheral arterial embolism diagnosed by CT. CASE PRESENTATION: We present a young man with sudden abdominal pain and flank tenderness without fever. Blood tests showed acute kidney failure. Computed tomography showed a right renal infarct and a non-circular thickening of the descending thoracic aortic wall with intra-luminal thrombus. Serology confirmed the diagnosis of syphilis. Treatment with anticoagulant and penicillin resulted in a good outcome. Follow-up PET-MRI showed resolution of the thrombus with a metabolically inactive atheromatous plaque. CONCLUSION: Technologies, such as CT, PET-CT and PET-MRI, that were not present during the pre-antibiotic era, can provide new insights into rare presentations of tertiary syphilis such as aortitis. These imaging modalities show promise for early radiological diagnosis of aortitis in syphilis and may be useful for determining the response to treatment in specific cases.
[Mh] Termos MeSH primário: Aortite/diagnóstico por imagem
Aortite/microbiologia
Infarto/diagnóstico por imagem
Sífilis Cardiovascular/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adulto
Antibacterianos/uso terapêutico
Aortite/tratamento farmacológico
Seres Humanos
Infarto/tratamento farmacológico
Infarto/microbiologia
Rim/irrigação sanguínea
Rim/diagnóstico por imagem
Imagem por Ressonância Magnética
Masculino
Penicilinas/uso terapêutico
Tomografia por Emissão de Pósitrons
Sífilis/diagnóstico por imagem
Sífilis/tratamento farmacológico
Sífilis Cardiovascular/tratamento farmacológico
Sífilis Cardiovascular/patologia
Tomografia Computadorizada por Raios X
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180120
[Lr] Data última revisão:
180120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1186/s12879-017-2624-1


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[PMID]:29206010
[Au] Autor:Bell V; Rui Pita J; Pereira AL
[Ti] Título:Regulation, circulation and distribution of penicillin in Portugal (1944-1954).
[So] Source:Dynamis;37(1):159-86, 2017.
[Is] ISSN:0211-9536
[Cp] País de publicação:Spain
[La] Idioma:eng
[Ab] Resumo:Portugal did not participate in World War II but was one of the first countries in the world to receive penicillin for civilian use. The Portuguese Red Cross began to import the antibiotic from the United States of America in 1944 and appointed a controlling committee to oversee its distribution, due to the small amount available. In 1945, as world production increased, penicillin began to be distributed through the normal channels. An important role in its regulation was played by the official department responsible for controlling pharmaceutical and chemical products in Portugal, the Comissão Reguladora dos Produtos Químicos e Farmacêuticos (Regulatory Committee for Chemical and Pharmaceutical Products). Penicillin was imported as a raw material from 1947 and the first medicaments containing penicillin, prepared in Portugal, were released into the commercial circuit in 1948. A laboratory had been established in 1942 by the Comissão Reguladora for the analytical verification of medicaments and medicinal products with the aim of certifying their quality and minimizing the number of products with no attested therapeutic efficacy. The number of medicaments analysed by this laboratory increased substantially from 72 in the year of its foundation (1942) to 2478 in 1954, including, after 1948, medicaments containing penicillin. The aim of the present paper was to elucidate the role of the Comissão Reguladora dos Produtos Químicos e Farmacêuticos in regulating and controlling the distribution of penicillin in Portugal during the 1940s and 1950s.
[Mh] Termos MeSH primário: Antibacterianos/história
Penicilinas/história
Saúde Pública/história
[Mh] Termos MeSH secundário: Antibacterianos/provisão & distribuição
História do Século XX
Penicilinas/provisão & distribuição
Portugal
Saúde Pública/legislação & jurisprudência
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:QIS
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


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[PMID]:29202152
[Au] Autor:Nunn A; Sturek JM; Reuss JE; Rein MF; Heysell SK
[Ad] Endereço:Department of Pediatrics, Penn State Health Children's Hospital, Hershey, PA, USA.
[Ti] Título:Subacute loss of vision in one eye · rash on hands and feet · plaques with scaling on genitals · Dx?
[So] Source:J Fam Pract;66(12):E9-E11, 2017 Dec.
[Is] ISSN:1533-7294
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A 67-year-old man presented to the hospital with subacute loss of vision in his left eye. The visual changes began 2 weeks earlier, with a central area of visual loss that had since progressed to near complete vision loss in the left eye. Physical examination revealed patchy alopecia, a scaling and hyperkeratotic rash of his hands and feet, and blanching, erythematous plaques with associated scaling on the scrotum and glans penis. Ophthalmologic examination revealed 1/200 vision in his left eye with a large plaque occupying a substantial portion of the superior quadrant, smaller perifoveal plaques in both of his eyes, and a small infiltrate above the left optic nerve head. The patient also described fatigue, loss of taste, and an unintentional weight loss of 7 to 10 kg over the previous 6 months. He had seen his primary care provider 3 months prior for a burning sensation and scaling rash on his feet and hands, and was prescribed a topical steroid.
[Mh] Termos MeSH primário: Infecções por HIV/diagnóstico
Sífilis/diagnóstico
[Mh] Termos MeSH secundário: Idoso
Antibacterianos/uso terapêutico
Fármacos Anti-HIV/uso terapêutico
Biópsia
Coinfecção
Ciclopentolato/uso terapêutico
Diagnóstico Diferencial
Exantema/diagnóstico
Exantema/tratamento farmacológico
Glucocorticoides/uso terapêutico
Infecções por HIV/tratamento farmacológico
Seres Humanos
Masculino
Midriáticos/uso terapêutico
Penicilinas/uso terapêutico
Prednisolona/uso terapêutico
Sífilis/tratamento farmacológico
Transtornos da Visão/diagnóstico
Transtornos da Visão/tratamento farmacológico
[Pt] Tipo de publicação:CASE REPORTS
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Anti-HIV Agents); 0 (Glucocorticoids); 0 (Mydriatics); 0 (Penicillins); 9PHQ9Y1OLM (Prednisolone); I76F4SHP7J (Cyclopentolate)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171208
[Lr] Data última revisão:
171208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE


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[PMID]:28743423
[Au] Autor:Geng B; Eastman JJ; Mori K; Braskett M; Riedl MA
[Ad] Endereço:Division of Rheumatology, Allergy and Immunology, University of California-San Diego, La Jolla, California. Electronic address: bgeng@ucsd.edu.
[Ti] Título:Utility of minor determinants for skin testing in inpatient penicillin allergy evaluation.
[So] Source:Ann Allergy Asthma Immunol;119(3):258-261, 2017 09.
[Is] ISSN:1534-4436
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Most patients with a history of penicillin allergy can tolerate penicillin. Skin testing can identify tolerant patients, but not all known allergenic determinants are commercially available. Protocols exist that use only available reagents, but the sensitivity and safety of these protocols, particularly for hospitalized patients, are controversial. OBJECTIVE: To determine the number of hospitalized patients referred for penicillin skin testing who showed unique positivity to the minor determinants penicilloate and penilloate. METHODS: A retrospective chart review was conducted of all inpatients who underwent penicillin skin testing at 1 institution. Patients were referred by their treating physician. All patients underwent skin prick testing to benzylpenicilloyl polylysine (major determinant), penicillin G, penicilloate, penilloate (minor determinants), amoxicillin, and positive and negative controls. If the result was negative, then intradermal testing was done with the same penicillin determinants and the negative control. A 4-mm wheal with flare was considered a positive reaction. RESULTS: Inpatient penicillin skin testing was done in 528 subjects. Any positive test reaction was found in 107 subjects (20%). Three subjects (3%) reacted to penilloate only, 25 (23%) reacted to penicilloate only, 2 (2%) reacted to penicillin G only, and 8 (8%) reacted to amoxicillin only. Sixty-eight subjects (64%) reacted to a compound other than the major determinant. CONCLUSION: This study found a high rate of exclusively positive skin test reactions to the minor determinants penicilloate and penilloate. Because patients with positive test reactions are at increased risk of reaction to drug challenge, these data support the use of these reagents for penicillin skin testing in hospitalized patients.
[Mh] Termos MeSH primário: Antibacterianos/efeitos adversos
Hipersensibilidade a Drogas/diagnóstico
Penicilinas/efeitos adversos
Testes Cutâneos/utilização
[Mh] Termos MeSH secundário: Seres Humanos
Pacientes Internados
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Penicillins)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171205
[Lr] Data última revisão:
171205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE


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[PMID]:28449020
[Au] Autor:Chatfield A; Glenie T; Fitzsimons S; Chaudhuri K; Looi KL
[Ad] Endereço:Cardiology Registrar, Green Lane Cardiovascular Service, Auckland City Hospital, Auckland.
[Ti] Título:S pneumoniae purulent pericarditis in the setting of community-acquired pneumonia.
[So] Source:N Z Med J;130(1454):80-85, 2017 04 28.
[Is] ISSN:1175-8716
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Mh] Termos MeSH primário: Pericardite/diagnóstico por imagem
Pneumonia Pneumocócica/complicações
Pneumonia Pneumocócica/diagnóstico por imagem
Streptococcus pneumoniae/isolamento & purificação
[Mh] Termos MeSH secundário: Fibrilação Atrial/diagnóstico
Infecções Comunitárias Adquiridas/microbiologia
Ecocardiografia Doppler
Eletrocardiografia
Seres Humanos
Masculino
Meia-Idade
Penicilinas/uso terapêutico
Pericardite/microbiologia
Pericardite/terapia
Pneumonia Pneumocócica/tratamento farmacológico
Radiografia Torácica
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Penicillins)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE



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