Base de dados : MEDLINE
Pesquisa : D02.092.877.096 [Categoria DeCS]
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  1 / 19 MEDLINE  
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[PMID]:26749383
[Au] Autor:Pan F; Beyeh NK; Bertella S; Rissanen K
[Ad] Endereço:University of Jyvaskyla, Finland, Department of Chemistry, Nanoscience Center, P.O. Box 35, FI-40014, Jyvaskyla, Finland.
[Ti] Título:Anion-Exchange Properties of Trifluoroacetate and Triflate Salts of N-Alkylammonium Resorcinarenes.
[So] Source:Chem Asian J;11(5):782-8, 2016 Mar 04.
[Is] ISSN:1861-471X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The synthesis of N-benzyl- and N-cyclohexylammonium resorcinarene trifluoroacetate (TFA) and triflate (OTf) salt receptors was investigated. Solid-state analysis by single-crystal X-ray diffraction revealed that the N-alkylammonium resorcinarene salts (NARSs) with different upper substituents had different cavity sizes and different affinities for anions. Anion-exchange experiments by mixing equimolar amounts of N-benzylammonium resorcinarene trifluoroacetate and N-cyclohexylammonium resorcinarene triflate, as well as N-benzylammonium resorcinarene triflate and N-cyclohexylammonium resorcinarene trifluoroacetate showed that the NARS with flexible benzyl groups preferred the larger OTf anion, whereas the rigid cyclohexyl groups preferred the smaller TFA anions. The anion-exchange processes were confirmed in the solid state by single-crystal and powder X-ray diffraction experiments and in the gas phase by electrospray ionization mass spectrometry.
[Mh] Termos MeSH primário: Ânions/química
Calixarenos/química
Mesilatos/química
Fenilalanina/análogos & derivados
Sais/química
Ácido Trifluoracético/química
[Mh] Termos MeSH secundário: Compostos de Benzilamônio/química
Cristalografia por Raios X
Dioxanos/química
Modelos Moleculares
Fenilalanina/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anions); 0 (Benzylammonium Compounds); 0 (Dioxanes); 0 (Mesylates); 0 (Salts); 0 (resorcinarene); 130036-26-9 (Calixarenes); 47E5O17Y3R (Phenylalanine); E5R8Z4G708 (Trifluoroacetic Acid); J8A3S10O7S (1,4-dioxane)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160111
[St] Status:MEDLINE
[do] DOI:10.1002/asia.201501335


  2 / 19 MEDLINE  
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[PMID]:26476203
[Au] Autor:Ndokoye P; Li X; Zhao Q; Li T; Tade MO; Liu S
[Ad] Endereço:Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), State Key Laboratory of Fine Chemicals, School of Environmental Science and Technology, Dalian University of Technology, Dalian 116024, China.
[Ti] Título:Gold nanostars: Benzyldimethylammonium chloride-assisted synthesis, plasmon tuning, SERS and catalytic activity.
[So] Source:J Colloid Interface Sci;462:341-50, 2016 Jan 15.
[Is] ISSN:1095-7103
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fabrication of Au nanostars (AuNSs) can expand the application range of Au nanoparticles because of their high electron density and localized surface plasmon resonance (LSPR) on branches. Exploiting this potential requires further refinement of length of the branches and radius of their tips. To this end, we successfully synthesized AuNSs with uniform and sharply-pointed branches by combining benzyldimethylammonium chloride (BDAC) and cetyltrimethylammonium bromide (CTAB) at low BDAC/CTAB ratios. Once mixed with CTAB, BDAC lowers the critical micelle concentration (CMC) for quick formation of the micelles, which provides favorable growth templates for AuNSs formation. Besides, BDAC increases the concentration of Cl(-), which favors Ag(+) in adsorbing on Au facets. This feature is crucial for the yield boosting and synergic shape control of AuNSs regardless of types of Au seeds used. Use of less amounts of seeds as the center of nucleation benefited sharper and longer growth of the branches. AuNSs exhibited excellent enhancement of surface-enhanced Raman scattering (SERS) intensities as the result of high electron density localized at the tips; however, the enhancement degree varied in accordance with the size of branches. In addition, AuNSs showed high catalytic performance toward the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP). Efficient catalysis over AuNSs originates from their corners, stepped surfaces and high electron density at the tips.
[Mh] Termos MeSH primário: Aminofenóis/síntese química
Compostos de Benzilamônio/química
Compostos de Cetrimônio/química
Ouro/química
Nanopartículas Metálicas/química
Nitrofenóis/química
[Mh] Termos MeSH secundário: Aminofenóis/química
Catálise
Micelas
Tamanho da Partícula
Análise Espectral Raman
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aminophenols); 0 (Benzylammonium Compounds); 0 (Cetrimonium Compounds); 0 (Micelles); 0 (Nitrophenols); 7440-57-5 (Gold); R7P8FRP05V (4-aminophenol); Y92ZL45L4R (4-nitrophenol); Z7FF1XKL7A (cetrimonium)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:151104
[Lr] Data última revisão:
151104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151018
[St] Status:MEDLINE


  3 / 19 MEDLINE  
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[PMID]:24991540
[Au] Autor:Adetunji VO; Kehinde AO; Bolatito OK; Chen J
[Ad] Endereço:Department of Veterinary Public Health and Preventive Medicine, University of Ibadan, Ibadan 2000005, Nigeria.
[Ti] Título:Biofilm formation by Mycobacterium bovis: influence of surface kind and temperatures of sanitizer treatments on biofilm control.
[So] Source:Biomed Res Int;2014:210165, 2014.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mycobacterium bovis causes classic bovine tuberculosis, a zoonosis which is still a concern in Africa. Biofilm forming ability of two Mycobacterium bovis strains was assessed on coupons of cement, ceramic, or stainless steel in three different microbiological media at 37°C with agitation for 2, 3, or 4 weeks to determine the medium that promotes biofilm. Biofilm mass accumulated on coupons was treated with 2 sanitizers (sanitizer A (5.5 mg L(-1) active iodine) and sanitizer B (170.6 g(1) alkyl dimethylbenzyl ammonium chloride, 78 g(-1) didecyldimethyl ammonium chloride, 107.25 g L(-1) glutaraldehyde, 146.25 g L(-1) isopropanol, and 20 g L(-1) pine oil) at 28 and 45°C and in hot water at 85°C for 5 min. Residual biofilms on treated coupons were quantified using crystal violet binding assay. The two strains had a similar ability to form biofilms on the three surfaces. More biofilms were developed in media containing 5% liver extract. Biofilm mass increased as incubation time increased till the 3rd week. More biofilms were formed on cement than on ceramic and stainless steel surfaces. Treatment with hot water at 85°C reduced biofilm mass, however, sanitizing treatments at 45°C removed more biofilms than at 28°C. However, neither treatment completely eliminated the biofilms. The choice of processing surface and temperatures used for sanitizing treatments had an impact on biofilm formation and its removal from solid surfaces.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Mycobacterium bovis/crescimento & desenvolvimento
Tuberculose/tratamento farmacológico
Tuberculose/microbiologia
[Mh] Termos MeSH secundário: Animais
Compostos de Benzilamônio/administração & dosagem
Biofilmes/efeitos dos fármacos
Bovinos
Contagem de Colônia Microbiana
Iodo/administração & dosagem
Mycobacterium bovis/patogenicidade
Propriedades de Superfície
Temperatura Ambiente
Tuberculose/veterinária
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Benzylammonium Compounds); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1502
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140704
[St] Status:MEDLINE
[do] DOI:10.1155/2014/210165


  4 / 19 MEDLINE  
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[PMID]:24238903
[Au] Autor:Lee H; Gold AS; Yang XF; Khanna R; Kohn H
[Ad] Endereço:Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7568, USA.
[Ti] Título:Benzyloxybenzylammonium chlorides: Simple amine salts that display anticonvulsant activity.
[So] Source:Bioorg Med Chem;21(24):7655-62, 2013 Dec 15.
[Is] ISSN:1464-3391
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Several antiepileptic drugs exert their activities by inhibiting Na(+) currents. Recent studies demonstrated that compounds containing a biaryl-linked motif (Ar-X-Ar') modulate Na(+) currents. We, and others, have reported that compounds with an embedded benzyloxyphenyl unit (ArOCH2Ar', OCH2=X) exhibit potent anticonvulsant activities. Here, we show that benzyloxybenzylammonium chlorides ((+)H3NCH2C6H4OCH2Ar' Cl(-)) displayed notable activities in animal seizure models. Electrophysiological studies of 4-(2'-trifluoromethoxybenzyloxy)benzylammonium chloride (9) using embryonic cortical neurons demonstrated that 9 promoted both fast and slow inactivation of Na(+) channels. These findings suggest that the potent anticonvulsant activities of the earlier compounds were due, in part, to the benzyloxyphenyl motif and provide support for the use of the biaryl-linked pharmacophore in future drug design efforts.
[Mh] Termos MeSH primário: Anticonvulsivantes/química
Anticonvulsivantes/farmacologia
Compostos de Benzilamônio/farmacologia
Córtex Cerebral/efeitos dos fármacos
Neurônios/efeitos dos fármacos
Éteres Fenílicos/farmacologia
Convulsões/tratamento farmacológico
[Mh] Termos MeSH secundário: Animais
Anticonvulsivantes/administração & dosagem
Compostos de Benzilamônio/administração & dosagem
Compostos de Benzilamônio/química
Relação Dose-Resposta a Droga
Camundongos
Estrutura Molecular
Éteres Fenílicos/administração & dosagem
Éteres Fenílicos/química
Ratos
Ratos Sprague-Dawley
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anticonvulsants); 0 (Benzylammonium Compounds); 0 (Phenyl Ethers)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:131203
[Lr] Data última revisão:
131203
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131119
[St] Status:MEDLINE


  5 / 19 MEDLINE  
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[PMID]:24180584
[Au] Autor:Ciao R; Talotta C; Gaeta C; Margarucci L; Casapullo A; Neri P
[Ad] Endereço:Dipartimento di Chimica e Biologia and NANO_MATES Research Center, Università di Salerno , Via Giovanni Paolo II 132, I-84084 Fisciano (Salerno), Italy, and Dipartimento di Farmacia, Università di Salerno , Via Giovanni Paolo II 132, I-84084 Fisciano (Salerno), Italy.
[Ti] Título:An oriented handcuff rotaxane.
[So] Source:Org Lett;15(22):5694-7, 2013 Nov 15.
[Is] ISSN:1523-7052
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The first example of an oriented handcuff rotaxane has been obtained by through-the-annulus threading of a double-calix[6]arene system with a bis-ammonium axle. The relative orientation of the two calix-wheels can be predefined by exploiting the "endo-alkyl rule" which controls the directionality of the threading of alkylbenzylammonium axles with calixarene macrocycles.
[Mh] Termos MeSH primário: Compostos de Benzilamônio/química
Calixarenos/química
Fenóis/química
Rotaxanos/síntese química
[Mh] Termos MeSH secundário: Estrutura Molecular
Rotaxanos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Benzylammonium Compounds); 0 (Phenols); 0 (Rotaxanes); 0 (calix(6)arene); 130036-26-9 (Calixarenes)
[Em] Mês de entrada:1404
[Cu] Atualização por classe:131115
[Lr] Data última revisão:
131115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131105
[St] Status:MEDLINE
[do] DOI:10.1021/ol4026974


  6 / 19 MEDLINE  
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[PMID]:23335629
[Au] Autor:Arges CG; Ramani V
[Ad] Endereço:Center for Electrochemical Science and Engineering, Department of Chemical and Biological Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
[Ti] Título:Two-dimensional NMR spectroscopy reveals cation-triggered backbone degradation in polysulfone-based anion exchange membranes.
[So] Source:Proc Natl Acad Sci U S A;110(7):2490-5, 2013 Feb 12.
[Is] ISSN:1091-6490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Anion exchange membranes (AEMs) find widespread applications as an electrolyte and/or electrode binder in fuel cells, electrodialysis stacks, flow and metal-air batteries, and electrolyzers. AEMs exhibit poor stability in alkaline media; their degradation is induced by the hydroxide ion, a potent nucleophile. We have used 2D NMR techniques to investigate polymer backbone stability (as opposed to cation stability) of the AEM in alkaline media. We report the mechanism behind a peculiar, often-observed phenomenon, wherein a demonstrably stable polysulfone backbone degrades rapidly in alkaline solutions upon derivatization with alkaline stable fixed cation groups. Using COSY and heteronuclear multiple quantum correlation spectroscopy (2D NMR), we unequivocally demonstrate that the added cation group triggers degradation of the polymer backbone in alkaline via quaternary carbon hydrolysis and ether hydrolysis, leading to rapid failure. This finding challenges the existing perception that having a stable cation moiety is sufficient to yield a stable AEM and emphasizes the importance of the often ignored issue of backbone stability.
[Mh] Termos MeSH primário: Antiporters/metabolismo
Cátions/metabolismo
Eletrólitos/metabolismo
Espectroscopia de Ressonância Magnética/métodos
Membranas Artificiais
Polímeros/metabolismo
Sulfonas/metabolismo
[Mh] Termos MeSH secundário: Compostos de Benzilamônio/química
Eletrólise
Eletrólitos/química
Estrutura Molecular
Polímeros/química
Sulfonas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Antiporters); 0 (Benzylammonium Compounds); 0 (Cations); 0 (Electrolytes); 0 (Membranes, Artificial); 0 (Polymers); 0 (Sulfones); 25135-51-7 (polysulfone P 1700)
[Em] Mês de entrada:1304
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130122
[St] Status:MEDLINE
[do] DOI:10.1073/pnas.1217215110


  7 / 19 MEDLINE  
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[PMID]:22612584
[Au] Autor:Yu D; Tian M; Fan Y; Ji G; Wang Y
[Ad] Endereço:Key Laboratory of Colloid and Interface Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.
[Ti] Título:Aggregate transitions in aqueous solutions of sodium dodecylsulfate with a "gemini-type" organic salt.
[So] Source:J Phys Chem B;116(22):6425-30, 2012 Jun 07.
[Is] ISSN:1520-5207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Effects of a "gemini-type" organic salt 1,2-bis(2-benzylammoniumethoxy) ethane dichloride (BEO) on the aggregation behavior of sodium dodecylsulfate (SDS) have been investigated by turbidity, surface tension, isothermal titration microcalorimetry, dynamic light scattering, cryogenic transmission electron microscopy, (1)H NMR spectroscopy, and differential scanning microcalorimetry. The aggregation behavior of the SDS/BEO mixed aqueous solution shows strong concentration and ratio dependence. For the SDS/BEO solution with a molar ratio of 5:1, large loose irregular aggregates, vesicles, and long thread-like micelles are formed in succession with the increase of the total SDS and BEO concentration. Because BEO has two positive charges, the SDS/BEO solution may consist of the (SDS)(2)-BEO gemini-type complex, the SDS-BEO complex and extra SDS. The aggregation ability and surface activity of the SDS/BEO mixture exhibit the characteristics of gemini-type surfactants. Along with the results of DSC and (1)H NMR, the (SDS)(2)-BEO gemini-type structure is confirmed to exist in the system. This work provides an approach to construct the surfactant systems with the characteristics of gemini surfactants through intermolecular interaction between a two-charged organic salt and oppositely charged single-chain surfactants.
[Mh] Termos MeSH primário: Compostos de Benzilamônio/química
Dodecilsulfato de Sódio/química
[Mh] Termos MeSH secundário: Modelos Moleculares
Estrutura Molecular
Tamanho da Partícula
Transição de Fase
Sais/química
Soluções
Propriedades de Superfície
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (1,2-bis(2-benzylammoniumethoxy)ethane dichloride); 0 (Benzylammonium Compounds); 0 (Salts); 0 (Solutions); 059QF0KO0R (Water); 368GB5141J (Sodium Dodecyl Sulfate)
[Em] Mês de entrada:1210
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120523
[St] Status:MEDLINE
[do] DOI:10.1021/jp211431g


  8 / 19 MEDLINE  
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[PMID]:22367690
[Au] Autor:Chai Y; Wang L; Sun H; Guo C; Pan Y
[Ad] Endereço:Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
[Ti] Título:Gas-phase chemistry of benzyl cations in dissociation of N-benzylammonium and N-benzyliminium ions studied by mass spectrometry.
[So] Source:J Am Soc Mass Spectrom;23(5):823-33, 2012 May.
[Is] ISSN:1879-1123
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In this study, the fragmentation reactions of various N-benzylammonium and N-benzyliminium ions were investigated by electrospray ionization mass spectrometry. In general, the dissociation of N-benzylated cations generates benzyl cations easily. Formation of ion/neutral complex intermediates consisting of the benzyl cations and the neutral fragments was observed. The intra-complex reactions included electrophilic aromatic substitution, hydride transfer, electron transfer, proton transfer, and nucleophilic aromatic substitution. These five types of reactions almost covered all the potential reactivities of benzyl cations in chemical reactions. Benzyl cations are well-known as Lewis acid and electrophile in reactions, but the present study showed that the gas-phase reactivities of some suitably ring-substituted benzyl cations were far richer. The 4-methylbenzyl cation was found to react as a Brønsted acid, benzyl cations bearing a strong electron-withdrawing group were found to react as electron acceptors, and para-halogen-substituted benzyl cations could react as substrates for nucleophilic attack at the phenyl ring. The reactions of benzyl cations were also related to the neutral counterparts. For example, in electron transfer reaction, the neutral counterpart should have low ionization energy and in nucleophilic aromatic substitution reaction, the neutral counterpart should be piperazine or analogues. This study provided a panoramic view of the reactions of benzyl cations with neutral N-containing species in the gas phase.
[Mh] Termos MeSH primário: Compostos de Benzilamônio/química
Iminas/química
Espectrometria de Massas/métodos
[Mh] Termos MeSH secundário: Cátions/química
Elétrons
Gases/química
Piperazinas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Benzylammonium Compounds); 0 (Cations); 0 (Gases); 0 (Imines); 0 (Piperazines)
[Em] Mês de entrada:1206
[Cu] Atualização por classe:171111
[Lr] Data última revisão:
171111
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120228
[St] Status:MEDLINE
[do] DOI:10.1007/s13361-012-0344-8


  9 / 19 MEDLINE  
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[PMID]:21434436
[Au] Autor:Xu WN; Gao XX; Guo XL; Chen YC; Zhang WM; Luo YS
[Ad] Endereço:Guangdong Pharmacetical University, Guangzhou 510006, China. girlweina.2008@163.com
[Ti] Título:[Study on volatile components from peel of Aquilaria sinensis and the anti-tumor activity].
[So] Source:Zhong Yao Cai;33(11):1736-40, 2010 Nov.
[Is] ISSN:1001-4454
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVE: To study the volatile constituents from peel of Aquilaria sinensis (Lour.) Gilg. and its anti-tumor activity. METHODS: The volatile components from peel of A. sinensis were extracted by chloroform and analysed by the GC-MS technique. Assay the peel extract of A. sinensis on MCF-7 cell proliferation using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) method. RESULTS: GC-MS gave 131 peaks and 28 compounds have been identified. The contents of the benzene compounds accounted 7.79% of the volatile components, the esquiterpenes accounted 5.44%, and the relative content of fatty acids accounted 3.08%. In addition, two 2-(2-phenylethyl)-color ketones and a chromone component were detected, and the total relative content accounted 12.3%. The inhibition rate of human breast cancer cells reached 99. 6% when the concentration was 500 microg/mL. CONCLUSION: The volatile components from peel of A. sinensis were analysed and a large number of characteristic elements of A. sinensis were detected for the first time. The chloroform extract from peel of A. sinensis significantly inhibited the proliferation of human breast cancer cells.
[Mh] Termos MeSH primário: Antineoplásicos Fitogênicos/farmacologia
Compostos de Benzilamônio/análise
Óleos Voláteis/análise
Sesquiterpenos/análise
Thymelaeaceae/química
[Mh] Termos MeSH secundário: Antineoplásicos Fitogênicos/isolamento & purificação
Compostos de Benzilamônio/farmacologia
Neoplasias da Mama/patologia
Linhagem Celular Tumoral
Proliferação Celular/efeitos dos fármacos
Cromonas/análise
Cromonas/farmacologia
Ácidos Graxos/análise
Ácidos Graxos/farmacologia
Feminino
Frutas/química
Cromatografia Gasosa-Espectrometria de Massas/métodos
Seres Humanos
Óleos Voláteis/química
Óleos Voláteis/farmacologia
Sesquiterpenos/farmacologia
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antineoplastic Agents, Phytogenic); 0 (Benzylammonium Compounds); 0 (Chromones); 0 (Fatty Acids); 0 (Oils, Volatile); 0 (Sesquiterpenes)
[Em] Mês de entrada:1105
[Cu] Atualização por classe:110324
[Lr] Data última revisão:
110324
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110326
[St] Status:MEDLINE


  10 / 19 MEDLINE  
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[PMID]:20879776
[Au] Autor:Xu XD; Yang HB; Zheng YR; Ghosh K; Lyndon MM; Muddiman DC; Stang PJ
[Ad] Endereço:Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai, China, 200062.
[Ti] Título:Self-assembly of dendritic tris(crown ether) hexagons and their complexation with dibenzylammonium cations.
[So] Source:J Org Chem;75(21):7373-80, 2010 Nov 05.
[Is] ISSN:1520-6904
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The construction of a new series of dendritic tris(crown ether) hexagons via coordination-driven self-assembly is described. Combining 120° crown ether-containing diplatinum(II) acceptors with 120° dendritic dipyridyl donors in a 1:1 ratio allows for the formation of a new family of dendritic triple crown ether derivatives with a hexagonal cavity in quantitative yields. The number and the position of these pendant groups can be precisely controlled on the hexagonal metallacycle. The structures of all dendritic multiple crown ether hexgaons are confirmed by multinuclear NMR ((1)H and (31)P), ESI-MS and ESI-TOF-MS, and elemental analysis. The complexation of these dendritic trivalent receptors with dibenzylammonium cations was investigated by (1)H NMR titration experiments. The thermodynamic binding constants between the receptors and guests were established by using the nonlinear least-squares fit method based on (1)H NMR titration experiments. It was found that the association constants of each assembly decrease correspondingly upon the increase of the generation of the dendrons from [G0] to [G3], which might be caused by the steric effect of the dendrons on host-guest complexation.
[Mh] Termos MeSH primário: Compostos de Benzilamônio/química
Éteres de Coroa/química
Dendrímeros/química
[Mh] Termos MeSH secundário: Espectroscopia de Ressonância Magnética
Modelos Moleculares
Conformação Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Benzylammonium Compounds); 0 (Crown Ethers); 0 (Dendrimers)
[Em] Mês de entrada:1102
[Cu] Atualização por classe:101029
[Lr] Data última revisão:
101029
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:101001
[St] Status:MEDLINE
[do] DOI:10.1021/jo101648p



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