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[PMID]:28854803
[Au] Autor:Flores-Ramírez G; Kmetová M; Danchenko M; Spitalská E; Havlícek V; Skultéty L
[Ti] Título:Protein composition of the phase I Coxiella burnetii soluble antigen prepared by extraction with trichloroacetic acid.
[So] Source:Acta Virol;61(3):361-368, 2017.
[Is] ISSN:0001-723X
[Cp] País de publicação:Slovakia
[La] Idioma:eng
[Ab] Resumo:Q fever is a highly infectious, widespread airborne zoonosis caused by Coxiella burnetii bacterium. Humans usually acquire the disease by inhalation of contaminated aerosol produced by infected livestock. Vaccination is the most practical way for prevention and control of the disease in the exposed population. In this work, we reviewed the most important Q-fever outbreaks in Slovakia as well as the progress in vaccine development. One of them represents a soluble antigen complex produced by extraction with trichloroacetic acid from a highly purified C. burnetii phase I strain Nine Mile. It was developed at the Institute of Virology in Bratislava. The protein content of this vaccine was separated by gel electrophoresis and analyzed by mass spectrometry. The study has resulted in the identification of 39 bacterial proteins from which 12 were recognized as immunoreactive. Most of the proteins were involved in bacterium pathogenicity (41.6%) and cell wall maintenance (25%). Four of the immunoreactive proteins may possess the moonlighting activity. Definition of the vaccine components represents a prerequisite for vaccine standardization and approval by governmental authorities.
[Mh] Termos MeSH primário: Antígenos de Bactérias/química
Antígenos de Bactérias/imunologia
Proteínas de Bactérias/química
Proteínas de Bactérias/imunologia
Coxiella burnetii/imunologia
Ácido Tricloroacético/química
[Mh] Termos MeSH secundário: Animais
Surtos de Doenças
Seres Humanos
Febre Q/epidemiologia
Febre Q/imunologia
Febre Q/microbiologia
Eslováquia/epidemiologia
Vacinação/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antigens, Bacterial); 0 (Bacterial Proteins); 5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.4149/av_2017_317


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[PMID]:28732800
[Au] Autor:Gonser P; Kaestner S; Jaminet P; Kaye K
[Ad] Endereço:Center for Plastic and Aesthetic Surgery, Ocean Clinic Marbella, Spain; Department for Plastic, Reconstructive, Hand and Burns Surgery, BG-Trauma Center, Eberhard Karls University Tuebingen, Germany. Electronic address: gophi@web.de.
[Ti] Título:Histological case-control study of peeling-induced skin changes by different peeling agents in surgically subcutaneous undermined skin flaps in facelift patients.
[So] Source:J Plast Reconstr Aesthet Surg;70(11):1660-1665, 2017 Nov.
[Is] ISSN:1878-0539
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A histological evaluation of peeling-induced skin changes in subcutaneous undermined preauricular facial skin flaps of nine patients was performed. There were three treatment groups: Trichloroacetic acid (TCA) 25%, TCA 40% and phenol/croton oil; one group served as control. Two independent evaluators determined the epidermal and dermal thickness and the depth of necrosis (micrometre). The percentual tissue damage due to the peeling was calculated, and a one-sample t-test for statistical significance was performed. On the basis of the histomorphological changes, peeling depth was classified as superficial, superficial-partial, deep-partial and full thickness chemical burn. The histological results revealed a progression of wound depth for different peeling agents without full thickness necrosis. TCA peels of up to 40% can be safely applied on subcutaneous undermined facial skin flaps without impairing the vascular patency, producing a predictable chemical burn, whereas deep peels such as phenol/croton oil peels should not be applied on subcutaneous undermined skin so as to not produce skin slough or necrosis by impairing vascular patency.
[Mh] Termos MeSH primário: Óleo de Cróton/efeitos adversos
Ritidoplastia/métodos
Dermatopatias/induzido quimicamente
Transplante de Pele/métodos
Pele/patologia
Retalhos Cirúrgicos
Ácido Tricloroacético/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Cáusticos/efeitos adversos
Fármacos Dermatológicos/efeitos adversos
Feminino
Seres Humanos
Meia-Idade
Pele/efeitos dos fármacos
Envelhecimento da Pele
Dermatopatias/patologia
Dermatopatias/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Caustics); 0 (Dermatologic Agents); 5V2JDO056X (Trichloroacetic Acid); 8001-28-3 (Croton Oil)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170723
[St] Status:MEDLINE


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[PMID]:28690305
[Au] Autor:Handa A; Kawanabe H; Ibe A
[Ad] Endereço:Jissen Women's University.
[Ti] Título:Determination of Nonvolatile Amines in Foods by Improved Dansyl Derivatization Reaction.
[So] Source:Shokuhin Eiseigaku Zasshi;58(3):149-154, 2017.
[Is] ISSN:1882-1006
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:An analytical method for the determination of nonvolatile amines (putrescine, cadaverine, histamine, tyramine, and spermidine) in foods was developed, using an improved dansyl derivatization technique. The five amines were extracted from food with 1% trichloroacetic acid. Three milliliter of extract was applied to a polymer-based strong cation exchange resin mini-column, which was washed with 5 mL of water, and eluted with 5 mL of 1 mol/L potassium carbonate solution. The eluate was dansylated, then 5 mL of toluene was added with shaking. The toluene layer was evaporated. The residue was taken up in 1 mL of acetonitrile and shaken with 1 mL of 5% proline in 1 mol/L potassium carbonate solution. The upper acetonitrile layer was collected, filtered, and subjected to HPLC. The limits of quantitation for putrescine and cadaverine in the samples were both 0.2 µg/g; those of spermidine, tyramine, and histamine were 0.8, 2.0, and 5.0 µg/g, respectively. The average recoveries of the five amines from nine foods exceeded 80%.
[Mh] Termos MeSH primário: Cromatografia Líquida de Alta Pressão/métodos
Compostos de Dansil
Análise de Alimentos/métodos
Histamina/análise
Tiramina/análise
[Mh] Termos MeSH secundário: Acetonitrilos
Cadaverina/análise
Cadaverina/isolamento & purificação
Histamina/isolamento & purificação
Putrescina/análise
Putrescina/isolamento & purificação
Extração em Fase Sólida/métodos
Soluções
Espermidina/análise
Espermidina/isolamento & purificação
Tolueno
Ácido Tricloroacético
Tiramina/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acetonitriles); 0 (Dansyl Compounds); 0 (Solutions); 3FPU23BG52 (Toluene); 5V2JDO056X (Trichloroacetic Acid); 820484N8I3 (Histamine); L90BEN6OLL (Cadaverine); QMU9166TJ4 (dansyl chloride); U87FK77H25 (Spermidine); V10TVZ52E4 (Putrescine); X8ZC7V0OX3 (Tyramine); Z072SB282N (acetonitrile)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.3358/shokueishi.58.149


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[PMID]:28572074
[Au] Autor:Cichocki JA; Furuya S; Venkatratnam A; McDonald TJ; Knap AH; Wade T; Sweet S; Chiu WA; Threadgill DW; Rusyn I
[Ad] Endereço:Department of Veterinary Integrative Biosciences.
[Ti] Título:Characterization of Variability in Toxicokinetics and Toxicodynamics of Tetrachloroethylene Using the Collaborative Cross Mouse Population.
[So] Source:Environ Health Perspect;125(5):057006, 2017 05 30.
[Is] ISSN:1552-9924
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evaluation of interindividual variability is a challenging step in risk assessment. For most environmental pollutants, including perchloroethylene (PERC), experimental data are lacking, resulting in default assumptions being used to account for variability in toxicokinetics and toxicodynamics. OBJECTIVE: We quantitatively examined the relationship between PERC toxicokinetics and toxicodynamics at the population level to test whether individuals with increased oxidative metabolism are be more sensitive to hepatotoxicity following PERC exposure. METHODS: Male mice from 45 strains of the Collaborative Cross (CC) were orally administered a single dose of PERC (1,000 mg/kg) or vehicle (Alkamuls-EL620) and euthanized at various time points (n = 1/strain/time). Concentration­time profiles were generated for PERC and its primary oxidative metabolite trichloroacetate (TCA) in multiple tissues. Toxicodynamic phenotyping was also performed. RESULTS: Significant variability among strains was observed in toxicokinetics of PERC and TCA in every tissue examined. Based on area under the curve (AUC), the range of liver TCA levels spanned nearly an order of magnitude (~8-fold). Expression of liver cytochrome P4502E1 did not correlate with TCA levels. Toxicodynamic phenotyping revealed an effect of PERC on bodyweight loss, induction of peroxisome proliferator activated receptor-alpha (PPARα)-regulated genes, and dysregulation of hepatic lipid homeostasis. Clustering was observed among ) liver levels of PERC, TCA, and triglycerides; ) TCA levels in liver and kidney; and ) TCA levels in serum, brain, fat, and lung. CONCLUSIONS: Using the CC mouse population model, we have demonstrated a complex and highly variable relationship between PERC and TCA toxicokinetics and toxicodynamics at the population level. https://doi.org/10.1289/EHP788.
[Mh] Termos MeSH primário: Tetracloroetileno/toxicidade
[Mh] Termos MeSH secundário: Animais
Peso Corporal/efeitos dos fármacos
Rim/química
Rim/efeitos dos fármacos
Fígado/química
Fígado/efeitos dos fármacos
Masculino
Camundongos
Oxirredução
PPAR alfa/metabolismo
Tetracloroetileno/administração & dosagem
Tetracloroetileno/farmacocinética
Toxicocinética
Ácido Tricloroacético/análise
Triglicerídeos/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (PPAR alpha); 0 (Triglycerides); 5V2JDO056X (Trichloroacetic Acid); TJ904HH8SN (Tetrachloroethylene)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170603
[St] Status:MEDLINE
[do] DOI:10.1289/EHP788


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[PMID]:28328702
[Au] Autor:Brody HJ
[Ad] Endereço:Department of Dermatology, Emory University, Atlanta, Georgia.
[Ti] Título:Commentary on Combined Jessner Solution and Trichloroacetic Acid Versus Trichloroacetic Acid Alone in the Treatment of Melasma in Dark-Skinned Patients.
[So] Source:Dermatol Surg;43(5):657, 2017 05.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Melanose
Ácido Tricloroacético
[Mh] Termos MeSH secundário: Abrasão Química
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Nm] Nome de substância:
5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170323
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000001122


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[PMID]:28178004
[Au] Autor:Abdel-Meguid AM; Taha EA; Ismail SA
[Ad] Endereço:*All authors are affiliated with the Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt.
[Ti] Título:Combined Jessner Solution and Trichloroacetic Acid Versus Trichloroacetic Acid Alone in the Treatment of Melasma in Dark-Skinned Patients.
[So] Source:Dermatol Surg;43(5):651-656, 2017 May.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Melasma is a common challenging pigmentary skin disorder especially in dark-skinned females urging them to seek medical help. Many modalities of treatment are available, but none is satisfactory. OBJECTIVE: To compare safety and efficacy of combined trichloroacetic acid (TCA) (20%-25%) and Jessner's solution versus TCA (20%-25%) alone in dark patients with melasma. MATERIALS AND METHODS: The study design was a split face, right-left, assessor-blinded, randomized controlled study. Twenty-four adult female patients (skin phototypes IV-V) with bilateral melasma were treated for 6 sessions at 2 weeks intervals. Clinical assessment of the 2 sides of the face with Melasma Area and Severity Index (MASI) score was performed, and photographs were taken before and after the peeling course. RESULTS: Both therapeutic modalities showed significant decrease in MASI score, which was significantly lower on the side treated with both Jessner solution and TCA. There were significant negative correlations between the percentage of improvement of MASI score and both age of the patients and duration of the melasma. CONCLUSION: Dark skin melasma can be treated with both regimens safely and effectively; however, combined Jessner solution and TCA is more effective.
[Mh] Termos MeSH primário: Abrasão Química/métodos
Etanol/uso terapêutico
Ácido Láctico/uso terapêutico
Melanose/terapia
Resorcinóis/uso terapêutico
Salicilatos/uso terapêutico
Ácido Tricloroacético/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Abrasão Química/efeitos adversos
Combinação de Medicamentos
Quimioterapia Combinada
Etanol/efeitos adversos
Feminino
Seres Humanos
Ácido Láctico/efeitos adversos
Meia-Idade
Resorcinóis/efeitos adversos
Salicilatos/efeitos adversos
Fatores de Tempo
Resultado do Tratamento
Ácido Tricloroacético/efeitos adversos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Drug Combinations); 0 (Jessner's solution); 0 (Resorcinols); 0 (Salicylates); 33X04XA5AT (Lactic Acid); 3K9958V90M (Ethanol); 5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170209
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000001036


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[PMID]:28148853
[Au] Autor:Grallert A; Hagan IM
[Ad] Endereço:CRUK Cell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester M20 4BX, United Kingdom Agnes.Grallert@cruk.manchester.ac.uk Iain.Hagan@cruk.manchester.ac.uk.
[Ti] Título:Large-Scale Immunoprecipitation from Fission Yeast Cell Extracts.
[So] Source:Cold Spring Harb Protoc;2017(2):pdb.prot091595, 2017 Feb 01.
[Is] ISSN:1559-6095
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:We outline immunoprecipitation (IP) procedures to isolate the large quantities of a molecule of interest that are required to identify posttranslational modifications (PTMs) in subsequent targeted mass spectrometry analysis. In situ denaturation by trichloroacetic acid precipitation inhibits the activities of modifying enzymes that could alter the PTM profile to preserve the PTMs on a target of interest throughout the precipitation step. In contrast, isolation of the same molecule with the nondenaturing variation on this IP procedure can maintain associations with partner molecules whose PTMs can also be mapped, albeit with the caveat that modifications could have occurred during the extended IP period.
[Mh] Termos MeSH primário: Misturas Complexas/química
Proteínas Fúngicas/isolamento & purificação
Imunoprecipitação/métodos
Schizosaccharomyces/química
[Mh] Termos MeSH secundário: Precipitação Química
Espectrometria de Massas
Desnaturação Proteica
Processamento de Proteína Pós-Traducional
Ácido Tricloroacético/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Complex Mixtures); 0 (Fungal Proteins); 5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1101/pdb.prot091595


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[PMID]:28148851
[Au] Autor:Grallert A; Hagan IM
[Ad] Endereço:CRUK Cell Division Group, Cancer Research UK Manchester Institute, University of Manchester, Manchester M20 4BX, United Kingdom Agnes.Grallert@cruk.manchester.ac.uk Iain.Hagan@cruk.manchester.ac.uk.
[Ti] Título:Preparation of Protein Extracts from Schizosaccharomyces pombe Using Trichloroacetic Acid Precipitation.
[So] Source:Cold Spring Harb Protoc;2017(2):pdb.prot091579, 2017 Feb 01.
[Is] ISSN:1559-6095
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Schizosaccharomyces pombe is an attractive model organism with which to study core principles of conserved molecular cell biology processes. The ability to monitor protein behavior following separation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) underpins much of this activity. Here we describe a robust protocol for the preparation of protein samples for analysis by SDS-PAGE.
[Mh] Termos MeSH primário: Precipitação Química
Proteínas Fúngicas/isolamento & purificação
Schizosaccharomyces/química
Ácido Tricloroacético/metabolismo
[Mh] Termos MeSH secundário: Cáusticos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Caustics); 0 (Fungal Proteins); 5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1101/pdb.prot091579


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[PMID]:28097306
[Au] Autor:Fanous N; Zari S
[Ad] Endereço:Division of Facial Plastic, Reconstructive and Esthetic Surgery, Department of Otolaryngology-Head and Neck Surgery, McGill University, Montreal, Quebec, Canada.
[Ti] Título:Universal Trichloroacetic Acid Peel Technique for Light and Dark Skin.
[So] Source:JAMA Facial Plast Surg;19(3):212-219, 2017 May 01.
[Is] ISSN:2168-6092
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Despite their great potential, medium and deep trichloroacetic acid peels are underused in light-skinned patients and are rarely used in darker-skinned patients because of the widespread fear of pigmentary complications and scarring. This concern has led many physicians to opt for the use of lighter types of peels (glycolic acid peel, Jessner peel, etc) and different lasers and intense light technologies. Trichloroacetic acid peels have been described in numerous publications. However, no study to date has described the precise technique and the practical pearls of a successful trichloroacetic acid peel approach in a clear, detailed, and reproducible manner. Objectives: To clarify a practical approach to a universal trichloroacetic acid peel and to offer novice and experienced facial plastic surgeons an organized, easy, and safe technique for medium and deep trichloroacetic acid peels. Design, Setting, and Participants: This study was a case series of universal trichloroacetic acid peels in an academic setting. The study dates were January 1, 1996, to November 1, 2015. Main Outcomes and Methods: This article discusses the preoperative evaluation for a chemical peel, a previously published genetico-racial skin classification, and the trichloroacetic acid peel technique, which aims at standardizing and controlling the application of the acid to improve results and lessen complications. The "strip" technique is described, which increases the physician's control over the peel depth. Results: A total of 923 trichloroacetic acid peels in 803 female patients (87.0%) and 120 male patients (13.0%) were reviewed (mean age, 41.59 years). The follow-up period ranged from 6 months to 13 years (mean, 13 months). This case series revealed a low incidence of complications, including 54 patients (5.9%) with persistent hyperpigmentation, 3 patients (0.3%) with mild telangiectasia, 2 patients (0.2%) with acute herpesvirus infection, 2 patients (0.2%) with bacterial Staphylococcus infection, and 1 patient (0.1%) with hypopigmentation. Conclusions and Relevance: When properly applied, trichloroacetic acid peels are efficient and safe for light and dark skin. The technique can be an easily implementable addition to a physician's cosmetic practice. Level of Evidence: 4.
[Mh] Termos MeSH primário: Abrasão Química/métodos
Dermatopatias/tratamento farmacológico
Pigmentação da Pele
Ácido Tricloroacético/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Abrasão Química/efeitos adversos
Feminino
Seres Humanos
Masculino
Dermatopatias/etnologia
Dermatopatias/etiologia
Resultado do Tratamento
Ácido Tricloroacético/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
5V2JDO056X (Trichloroacetic Acid)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170119
[St] Status:MEDLINE
[do] DOI:10.1001/jamafacial.2016.1666


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[PMID]:27998025
[Au] Autor:El Mofty M; Esmat S; Hunter N; Mashaly HM; Dorgham D; Shaker O; Ibrahim S
[Ad] Endereço:Dermatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
[Ti] Título:Effect of different types of therapeutic trauma on vitiligo lesions.
[So] Source:Dermatol Ther;30(2), 2017 Mar.
[Is] ISSN:1529-8019
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:New treatment modalities for vitiligo acting by changing certain cytokines and metalloproteinases are newly emerging. The aim of this work is to To assess the efficacy of trichloroacetic acid (TCA) chemical peel, dermapen, and fractional CO laser in treatment of stable non-segmental vitiligo and to detect their effects on IL-17 and MMP-9 levels. Thirty patients with stable vitiligo were recruited in a randomized controlled study. They were randomly categorized into three equal groups. Group 1: TCA peel, Group 2: dermapen machine, and Group 3: Fractional CO laser. Skin biopsies were taken from treated areas and from control areas for which MMP-9 and IL-17 tissue levels were measured using ELISA. The 30 vitiligo patients had low basal tissue MMP-9 levels and high baseline IL-17 tissue levels. As regards the three different used modalities, all of them caused rise in MMP-9 as well as IL-17 levels and almost their levels were much more elevated with repetition of the previously mentioned traumatic procedures. TCA 25% peel proved to be the most effective modality both clinically and laboratory and it can be used prior or with other conventional therapies in the treatment of vitiligo.
[Mh] Termos MeSH primário: Cáusticos/administração & dosagem
Abrasão Química
Técnicas Cosméticas
Lasers de Gás/uso terapêutico
Terapia com Luz de Baixa Intensidade/instrumentação
Pigmentação da Pele
Pele
Ácido Tricloroacético/administração & dosagem
Vitiligo/terapia
[Mh] Termos MeSH secundário: Administração Cutânea
Adolescente
Adulto
Biópsia
Cáusticos/efeitos adversos
Abrasão Química/efeitos adversos
Técnicas Cosméticas/efeitos adversos
Técnicas Cosméticas/instrumentação
Egito
Feminino
Seres Humanos
Interleucina-17/metabolismo
Lasers de Gás/efeitos adversos
Terapia com Luz de Baixa Intensidade/efeitos adversos
Masculino
Metaloproteinase 9 da Matriz/metabolismo
Meia-Idade
Miniaturização
Agulhas
Pele/efeitos dos fármacos
Pele/enzimologia
Pele/imunologia
Pele/efeitos da radiação
Pigmentação da Pele/efeitos dos fármacos
Pigmentação da Pele/efeitos da radiação
Fatores de Tempo
Resultado do Tratamento
Ácido Tricloroacético/efeitos adversos
Vitiligo/diagnóstico
Vitiligo/enzimologia
Vitiligo/imunologia
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Caustics); 0 (Interleukin-17); 5V2JDO056X (Trichloroacetic Acid); EC 3.4.24.35 (MMP9 protein, human); EC 3.4.24.35 (Matrix Metalloproteinase 9)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161221
[St] Status:MEDLINE
[do] DOI:10.1111/dth.12447



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