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[PMID]:29408856
[Au] Autor:Kimura-Suda H; Takahata M; Ito T; Shimizu T; Kanazawa K; Ota M; Iwasaki N
[Ad] Endereço:Graduate School of Photonics Science, Chitose Institute of Science and Technology, Chitose, Hokkaido, Japan.
[Ti] Título:Quick and easy sample preparation without resin embedding for the bone quality assessment of fresh calcified bone using fourier transform infrared imaging.
[So] Source:PLoS One;13(2):e0189650, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fourier transform infrared (FTIR) imaging is a powerful tool for the assessment of bone quality; however, it requires the preparation of thin bone sections. Conventional poly(methyl methacrylate) (PMMA) embedding for the preparation of sections takes more than two weeks and causes denaturation of the bone. Development of a quick and easy sample preparation technique without denaturation is needed for accurate clinical evaluation of fresh calcified bone using FTIR imaging. Frozen sectioning allows the quick and easy preparation of thin sections without denaturation, but it requires a substrate with good chemical resistance and improved heat shock resistance. Polypropylene (PP) film afforded both good chemical resistance and greater heat shock resistance, and the 4-µm-thick PP film coated with glue was thin enough for the IR beam to pass through it, while the optical anisotropy of infrared bands overlapping with PO43- band was negligible. The bone quality of femoral thin sections prepared by the conventional PMMA embedding and sectioning procedure (RESIN-S) or the newly developed frozen sectioning procedure (FROZEN-S) was evaluated by FTIR imaging. The mineral-to-matrix ratio and crystallinity in the RESIN-S sections were higher than those in the FROZEN-S sections, whereas the carbonate-to-phosphate ratio in the RESIN-S sections was lower than that in the FROZEN-S sections. In RESIN-S, the increased mineral-to-matrix ratio could be caused by dehydration, and the increased crystallinity and decreased carbonate-to-phosphate ratio might be consequence of dissolution of bone mineral during PMMA embedding. Therefore, the combined use of PP film coated with glue and the frozen sectioning procedure without denaturation appears well suited to the assessment of the bone quality of fresh calcified bone using FTIR imaging.
[Mh] Termos MeSH primário: Osso e Ossos/diagnóstico por imagem
Calcificação Fisiológica
Espectroscopia de Infravermelho com Transformada de Fourier/métodos
[Mh] Termos MeSH secundário: Alcenos
Animais
Camundongos
Camundongos Endogâmicos BALB C
Polimetil Metacrilato
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alkenes); 9011-14-7 (Polymethyl Methacrylate); AUG1H506LY (propylene)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180309
[Lr] Data última revisão:
180309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180207
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0189650


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[PMID]:29458673
[Au] Autor:Morse DJ; Wilson MJ; Wei X; Lewis MAO; Bradshaw DJ; Murdoch C; Williams DW
[Ad] Endereço:1​Oral and Biomedical Sciences, School of Dentistry, Cardiff University, Cardiff, UK.
[Ti] Título:Denture-associated biofilm infection in three-dimensional oral mucosal tissue models.
[So] Source:J Med Microbiol;67(3):364-375, 2018 Mar.
[Is] ISSN:1473-5644
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: In vitro analyses of virulence, pathogenicity and associated host cell responses are important components in the study of biofilm infections. The Candida-related infection, denture-associated oral candidosis, affects up to 60 % of denture wearers and manifests as inflammation of palatal tissues contacting the denture-fitting surface. Commercially available three-dimensional tissue models can be used to study infection, but their use is limited for many academic research institutions, primarily because of the substantial purchase costs. The aim of this study was to develop and evaluate the use of in vitro tissue models to assess infections by biofilms on acrylic surfaces through tissue damage and Candida albicans virulence gene expression. METHODOLOGY: In vitro models were compared against commercially available tissue equivalents (keratinocyte-only, SkinEthic; full-thickness, MatTek Corporation). An in vitro keratinocyte-only tissue was produced using a cancer-derived cell line, TR146, and a full-thickness model incorporating primary fibroblasts and immortalised normal oral keratinocytes was also generated. The in vitro full-thickness tissues incorporated keratinocytes and fibroblasts, and have potential for future further development and analysis. RESULTS: Following polymicrobial infection with biofilms on acrylic surfaces, both in-house developed models were shown to provide equivalent results to the SkinEthic and MatTek models in terms of tissue damage: a significant (P<0.05) increase in LDH activity for mixed species biofilms compared to uninfected control, and no significant difference (P>0.05) in the expression of most C. albicans virulence genes when comparing tissue models of the same type. CONCLUSION: Our results confirm the feasibility and suitability of using these alternative in vitro tissue models for such analyses.
[Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento
Candidíase Bucal/microbiologia
Dentaduras/microbiologia
Interações Hospedeiro-Patógeno
Mucosa Bucal/microbiologia
[Mh] Termos MeSH secundário: Candida albicans/genética
Candida albicans/patogenicidade
Candida albicans/fisiologia
Linhagem Celular
Coinfecção/microbiologia
Fibroblastos/microbiologia
Seres Humanos
Queratinócitos/microbiologia
Polimetil Metacrilato
Estomatite sob Prótese
Virulência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180221
[St] Status:MEDLINE
[do] DOI:10.1099/jmm.0.000677


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[PMID]:29182217
[Au] Autor:Pispili M; Pissiotis A; Michalakis K
[Ad] Endereço:Aristotle University of Thessaloniki.
[Ti] Título:The Effect of Surface Preparation of Acrylic Teeth.
[So] Source:Eur J Prosthodont Restor Dent;25(4):209-218, 2017 Dec 01.
[Is] ISSN:0965-7452
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To investigate whether the chemical bond between acrylic teeth and heat polymerized PMMA can be altered by chemical and/or mechanical treatment. MATERIALS AND METHODS: One hundred fifty acrylic teeth were divided in groups of 10. Their ridge lap surface underwent mechanical and/or chemical treatments: 1) no treatment, 2) air-abrasion with Al2O3 particles, 3) acid etching with phosphoric acid, 4) application of composite resin bonding agent, 5) application of MMA and ethylmethylketone bonding agent, 6) PMMA monomer application. The teeth were then placed in heat polymerized acrylic resin. Each specimen was compressed with a universal testing machine. Descriptive statistics, one-way ANOVA (α=0.05) and Tukey's HSD test were used. A scanning electron microscope (SEM) was also used to study the fracture areas. RESULTS: Statistically significant differences (p⟨0.001) in the bond strength were found. The strongest bond (239.41 N), was noted in the group treated with sandblasting followed by PMMA monomer application. CONCLUSIONS: Mechanical and/or chemical preparations affect significantly the bond strength between the acrylic resin denture teeth and the PMMA denture base. Air abrasion was the most effective treatment, either alone or combined with other treatments.
[Mh] Termos MeSH primário: Resinas Acrílicas
Colagem Dentária
Materiais Dentários
Polimetil Metacrilato
Preparo Prostodôntico do Dente
[Mh] Termos MeSH secundário: Teste de Materiais
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylic Resins); 0 (Dental Materials); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:171129
[St] Status:MEDLINE
[do] DOI:10.1922/EJPRD_01713Pispili10


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[PMID]:29382020
[Au] Autor:Zhang C; Wang G; Liu X; Li Y; Sun J
[Ad] Endereço:Department of Spine, Shandong Provincial Hospital Affiliated to Shandong University,Shandong Province.
[Ti] Título:Failed percutaneous kyphoplasty in treatment of stage 3 Kummell disease: A case report and literature review.
[So] Source:Medicine (Baltimore);96(47):e8895, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Albeit it is rare, the authors report a stage 3 Kummell disease case. It is diagnosed by dynamic thoracic magnetic resonance imaging (MRI). Because there is no established strategy on stage 3 Kummell disease, we performed percutaneous kyphoplasty at first, but unfortunately made a revision surgery to remove the polymethylmethacrylate (PMMA) cement after the failure of percutaneous kyphoplasty. PATIENT CONCERNS: A 73-year-old lady with severe back pain due to osteoporosis vertebral fracture was admitted to our hospital on June 23, 2016. She underwent percutaneous kyphoplasty with the back pain improved shortly. Unfortunately, she went back to our hospital due to aggravated back pain and partial paralysis on July 25, 2016. DIAGNOSES: Kummell disease, lumbar stenosis, lacunar infarction. OUTCOMES: Specially, the compression of spinal cord was obvious in the hyperflexion position on dynamic MRI. Even though there was no improvement in muscle strength, the patient was satisfied with the back pain relief after percutaneous kyphoplasty. But, the same back pain reappeared after about 1 month. Then, we took out the PMMA cement and performed posterior vertebral column resection. At last, the back pain was relieved again but the muscle strength was improved not obviously after operation. At the same time, the kyphosis was corrected and the intravertebral stability was achieved. LESSONS: Dynamic MRI is helpful in Kummell disease with neurologic symptoms, even if there is no obvious compression in the neutral position. Furthermore, the intravertebral instability is probably the main reason of the neurologic symptoms in this case. Percutaneous kyphoplasty could not reconstruct the intravertebral stability. Stage 3 Kummell disease with obvious intravertebral instability should be treated by open surgery.
[Mh] Termos MeSH primário: Cifoplastia/efeitos adversos
Cifose/cirurgia
Reoperação/métodos
Fraturas da Coluna Vertebral/complicações
[Mh] Termos MeSH secundário: Idoso
Cimentos para Ossos
Feminino
Seres Humanos
Cifoplastia/métodos
Cifose/etiologia
Fraturas por Osteoporose/complicações
Polimetil Metacrilato
Falha de Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Bone Cements); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008895


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[PMID]:27774773
[Au] Autor:Mallinson D; Cheung DL; Simionesie D; Mullen AB; Zhang ZJ; Lamprou DA
[Ad] Endereço:Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, 161 Cathedral Street, Glasgow, United Kingdom.
[Ti] Título:Experimental and computational examination of anastellin (FnIII1c)-polymer interactions.
[So] Source:J Biomed Mater Res A;105(3):737-745, 2017 03.
[Is] ISSN:1552-4965
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Using a combination of experimental and computational approaches, the interaction between anastellin, a recombinant fragment of fibronectin, and representative biomaterial surfaces has been examined. Anastellin and superfibronectin have been seen to exhibit antiangiogenic properties and other properties that may make it suitable for consideration for incorporation into biomaterials. The molecular interaction was directly quantified by atomic force microscope (AFM)-based force spectroscopy, complemented by adsorption measurements using quartz crystal microbalance (QCM). Using AFM, it was found that the anastellin molecule facilitates a stronger adhesion on polyurethane films (72.0 pN nm ) than on poly (methyl methacrylate) films (68.6 pN nm ). However, this is not consistent with the QCM adsorption measurements, which show no significant difference. Molecular dynamics simulations of the behavior of anastellin on polyurethane in aqueous solution were performed to rationalize the experimental data, and show that anastellin is capable of rapid adsorption to PU while its secondary structure is stable upon adsorption in water. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 737-745, 2017.
[Mh] Termos MeSH primário: Fibronectinas/química
Membranas Artificiais
Fragmentos de Peptídeos/química
Polimetil Metacrilato/química
Poliuretanos/química
[Mh] Termos MeSH secundário: Seres Humanos
Microscopia de Força Atômica
Técnicas de Microbalança de Cristal de Quartzo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Fibronectins); 0 (Membranes, Artificial); 0 (Peptide Fragments); 0 (Polyurethanes); 0 (anastellin); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171225
[Lr] Data última revisão:
171225
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1002/jbm.a.35949


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[PMID]:27770338
[Au] Autor:Wilairatana V; Sinlapavilawan P; Honsawek S; Limpaphayom N
[Ad] Endereço:Department of Orthopaedics, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.
[Ti] Título:Alteration of inflammatory cytokine production in primary total knee arthroplasty using antibiotic-loaded bone cement.
[So] Source:J Orthop Traumatol;18(1):51-57, 2017 Mar.
[Is] ISSN:1590-9999
[Cp] País de publicação:Italy
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The aim was to compare serum levels of interleukin-6 (SIL6), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and joint fluid IL-6 (JIL-6) level between total knee arthroplasty (TKA) that used bone cement (BC group) and antibiotic-loaded bone cement (ALBC group). MATERIALS AND METHODS: Thirty-nine patients (40 TKAs) with a mean age of 69.6 years were non-randomly assigned to the BC or ALBC groups. Samples of SIL6, ESR, and CRP were collected at baseline and at 24 h, 72 h, and 4 weeks after surgery. JIL-6 levels were collected intraoperatively before joint arthrotomy, before finishing the procedure and 24 h after surgery. Postoperative mediator levels were compared with baseline levels within the same group and between groups at each time point. Knee Society Score-knee (KSSK) and Knee Society Score-function (KSSF) scores were evaluated. RESULTS: SIL-6, ESR, and CRP levels were significantly elevated at 24 and 72 h, compared to baseline. Only SIL-6 levels at 72 h in the ALBC group showed a significantly lower level than those in the BC group. JIL-6 levels were not different between groups. There were no significant differences in KSSK or KSSF scores between groups at 4 weeks and the most recent follow-up (1.4 ± 0.6 years) evaluation. No correlations were identified among SIL-6 and JIL-6 levels at 24 and 72 h, and KSSK and KSSF scores at 4 weeks and at the most recent evaluation. CONCLUSIONS: ALBC showed a favorable immunomodulatory effect and lower SIL-6 level at 72 h following TKA compared to BC, although functional benefits require further investigation. LEVEL OF EVIDENCE: OCEBM, Level 3.
[Mh] Termos MeSH primário: Antibacterianos/uso terapêutico
Artroplastia do Joelho
Cimentos para Ossos/uso terapêutico
Interleucina-6/metabolismo
Osteoartrite do Joelho/metabolismo
Osteoartrite do Joelho/cirurgia
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Sedimentação Sanguínea
Proteína C-Reativa/metabolismo
Feminino
Seres Humanos
Masculino
Meia-Idade
Polimetil Metacrilato/uso terapêutico
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Bone Cements); 0 (IL6 protein, human); 0 (Interleukin-6); 0 (Palacos R+G); 9007-41-4 (C-Reactive Protein); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171211
[Lr] Data última revisão:
171211
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE
[do] DOI:10.1007/s10195-016-0432-9


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[PMID]:28832713
[Au] Autor:Rodrigues JA; Tenorio IP; Mello GBR; Reis AF; Shen C; Roulet JF
[Ad] Endereço:Universidade Guarulhos - UNG, Department of Restorative Dentistry, Dental Research and Graduate Studies Division, Guarulhos, SP, Brazil.
[Ti] Título:Comparing depth-dependent curing radiant exposure and time of curing of regular and flow bulk-fill composites.
[So] Source:Braz Oral Res;31:e65, 2017 Aug 21.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The effect of restoration depth on the curing time of a conventional and two bulk-fill composite resins by measuring microhardness and the respective radiosity of the bottom surface of the specimen was investigated. 1-, 3- and 5-mm thick washers were filled with Surefil SDR Flow-U (SDR), Tetric EvoCeram Bulk Fill-IVA (TEC) or Esthet-X HD-B1 (EHD), and cured with Bluephase® G2 for 40s. Additional 1-mm washers were filled with SDR, TEC or EHD, placed above the light sensor of MARC®, stacked with pre-cured 1-, 3- or 5-mm washer of respective material, and cured for 2.5~60s to mimic 2-, 4- and 6-mm thick composite curing. The sensor measured the radiosity (EB) at the bottom of specimen stacks. Vickers hardness (VH) was measured immediately at 5 locations with triplicate specimens. Nonlinear regression of VH vs EB by VH=α[1-exp(-EB/ß)] with all thickness shows that the values of α, maximum hardness, are 21.6±1.0 kg/mm2 for SDR, 38.3±0.6 kg/mm2 for TEC and 45.3±2.6 kg/mm2 for EHD, and the values of ß, rate parameter, are 0.40±0.06 J/cm2 for SDR, 0.77±0.04 J/cm2 for TEC and 0.58±0.09 J/cm2 for EHD. The radiosity of the bottom surface was calculated when the bottom surface of each material attained 80% of α of each material. The curing times for each material are in agreement with manufacturer recommendation for thickness. It is possible to estimate time needed to cure composite resin of known depth adequately by the radiosity and microhardness of the bottom surface.
[Mh] Termos MeSH primário: Resinas Compostas/química
Resinas Compostas/efeitos da radiação
Luzes de Cura Dentária
Cura Luminosa de Adesivos Dentários/métodos
[Mh] Termos MeSH secundário: Análise de Variância
Testes de Dureza
Modelos Lineares
Teste de Materiais
Polimerização
Polimetil Metacrilato/química
Polimetil Metacrilato/efeitos da radiação
Dose de Radiação
Valores de Referência
Cimentos de Resina/química
Cimentos de Resina/efeitos da radiação
Propriedades de Superfície/efeitos da radiação
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Composite Resins); 0 (Esthet-X); 0 (Ivoclar Universal Cement); 0 (Resin Cements); 0 (Surefil SDR Flow); 0 (Tetric EvoCeram); 52051-37-3 (CMW cement); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE


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[PMID]:28753275
[Au] Autor:Sharma R; Kapusetti G; Bhong SY; Roy P; Singh SK; Singh S; Balavigneswaran CK; Mahato KK; Ray B; Maiti P; Misra N
[Ti] Título:Osteoconductive Amine-Functionalized Graphene-Poly(methyl methacrylate) Bone Cement Composite with Controlled Exothermic Polymerization.
[So] Source:Bioconjug Chem;28(9):2254-2265, 2017 Sep 20.
[Is] ISSN:1520-4812
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Bone cement has found extensive usage in joint arthroplasty over the last 50 years; still, the development of bone cement with essential properties such as high fatigue resistance, lower exothermic temperature, and bioactivity has been an unsolved problem. In our present work, we have addressed all of the mentioned shortcomings of bone cement by reinforcing it with graphene (GR), graphene oxide (GO), and surface-modified amino graphene (AG) fillers. These nanocomposites have shown hypsochromic shifts, suggesting strong interactions between the filler material and the polymer matrix. AG-based nanohybrids have shown greater osteointegration and lower cytotoxicity compared to other nanohybrids as well as pristine bone cement. They have also reduced oxidative stress on cells, resulting in calcification within 20 days of the implantation of nanohybrids into the rabbits. They have significantly reduced the exothermic curing temperature to body temperature and increased the setting time to facilitate practitioners, suggesting that reaction temperature and settling time can be dynamically controlled by varying the concentration of the filler. Thermal stability and enhanced mechanical properties have been achieved in nanohybrids vis-à-vis pure bone cement. Thus, this newly developed nanocomposite can create natural bonding with bone tissues for improved bioactivity, longer sustainability, and better strength in the prosthesis.
[Mh] Termos MeSH primário: Cimentos para Ossos/química
Grafite/química
Nanocompostos/química
Polimetil Metacrilato/química
[Mh] Termos MeSH secundário: Aminação
Animais
Substitutos Ósseos/química
Linhagem Celular
Seres Humanos
Teste de Materiais
Nanocompostos/ultraestrutura
Osseointegração
Osteogênese
Polimerização
Coelhos
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bone Cements); 0 (Bone Substitutes); 7782-42-5 (Graphite); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171009
[Lr] Data última revisão:
171009
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170729
[St] Status:MEDLINE
[do] DOI:10.1021/acs.bioconjchem.7b00241


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[PMID]:28690739
[Au] Autor:Hemama M; El Fatemi N; Gana R
[Ad] Endereço:UFR d''Epidémiologie Clinique et Sciences Médico-Chirurgicale, Ertna-Mohammed V University- Souissi (UM5S)-Faculty of Medicine and Pharmacy, Rabat, Morocco.
[Ti] Título:Percutaneous vertebroplasty in Moroccan patients with vertebral compression fractures.
[So] Source:Pan Afr Med J;26:225, 2017.
[Is] ISSN:1937-8688
[Cp] País de publicação:Uganda
[La] Idioma:eng
[Ab] Resumo:Incidence of vertebral compression fractures (VCFs) is increasing due to the increase in human life expectancy and prevalence of osteoporosis. Percutaneous vertebroplasty (PVP) has become a widely used alternative treatment for symptomatic VCFs refractory to medical therapy. It is a minimally invasive technique involving injection most frequently of polymethylmethacrylate (PMMA) directly into the vertebral body through the pedicles. Percutaneous vertebroplasty yields good results in terms of early vertebral stabilization and prompt pain relief. This study describes the experience of the Department of Neurosurgery at Ibn Sina University Hospital (Rabat, Morocco) and assesses short and long term clinical and radiological outcomes and complications of vertebroplasty in a retrospective assessment of 36 vertebral compression fractures in 35 patients (16 men and 19 women subjects) who had been treated with vertebroplasty from November 2006 to December 2014.
[Mh] Termos MeSH primário: Fraturas por Compressão/cirurgia
Fraturas da Coluna Vertebral/cirurgia
Vertebroplastia/métodos
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seguimentos
Fraturas por Compressão/diagnóstico por imagem
Hospitais Universitários
Seres Humanos
Masculino
Meia-Idade
Marrocos
Polimetil Metacrilato/administração & dosagem
Complicações Pós-Operatórias/epidemiologia
Estudos Retrospectivos
Fraturas da Coluna Vertebral/diagnóstico por imagem
Resultado do Tratamento
Vertebroplastia/efeitos adversos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170719
[Lr] Data última revisão:
170719
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170711
[St] Status:MEDLINE
[do] DOI:10.11604/pamj.2017.26.225.9872


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[PMID]:28658059
[Au] Autor:Frank SJ; Kearfott KJ
[Ad] Endereço:*University of Michigan, Department of Nuclear Engineering and Radiological Sciences, Ann Arbor, MI 48109-2104.
[Ti] Título:Imaging of Gamma-ray Scatter from a Polymethyl-methacrylate Phantom Using a Compton Imaging Spectrometer.
[So] Source:Health Phys;113(2):135-142, 2017 Aug.
[Is] ISSN:1538-5159
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Commercially available gamma-ray imaging spectrometers have been introduced recently and are currently undergoing investigations for various applications in nuclear power plants, environmental management, and medical environments. A Compton imaging gamma-ray spectrometer uses an array of detectors or a single position-sensitive crystal to create planar images of radionuclide distributions. The typical software included with these devices creates images of specific radionuclides using only the counts under their known gamma emission photopeaks. This approach prevents the direct imaging of scattered radiation, which is of interest for many radiation protection applications. In this paper, a technique for imaging radiation scatter or portions of the scatter spectrum is implemented. This involves the creation of a virtual radionuclide in software with peaks placed throughout the backscatter continuum of interest and then imaging that virtual radionuclide in the post-processing software. This technique is used to image the Compton scatter successfully from a polymethyl-methacrylate (PMMA) phantom placed in a Cs irradiator beam. Measured scatter energies were found to be within 15% of the expected values, sufficient to predict scatter behavior and individually measure separate sources of scatter at different angles.
[Mh] Termos MeSH primário: Materiais Biomiméticos/química
Césio/análise
Raios gama
Imagens de Fantasmas
Polimetil Metacrilato/química
Espectrometria gama/instrumentação
[Mh] Termos MeSH secundário: Desenho de Equipamento
Análise de Falha de Equipamento
Seres Humanos
Dose de Radiação
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
1KSV9V4Y4I (Cesium); 9011-14-7 (Polymethyl Methacrylate)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1097/HP.0000000000000681



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