[PMID]: | 28422869 |
[Au] Autor: | Dai YC; Zheng L; Zhang YL; Chen X; Chen DL; Tang ZP |
[Ad] Endereço: | Institute of Digestive Disease, China-Canada Center of Research for Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. |
[Ti] Título: | Effects of Jianpi Qingchang decoction on the quality of life of patients with ulcerative colitis: A randomized controlled trial. |
[So] Source: | Medicine (Baltimore);96(16):e6651, 2017 Apr. |
[Is] ISSN: | 1536-5964 |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | This study aims to determine the effects of the Jianpi Qingchang decoction (JQD) on the quality of life (QOL) of patients with spleen deficiency and dampness-heat syndrome ulcerative colitis (UC).A total of 120 active UC patients with spleen deficiency and dampness-heat syndrome were enrolled into this study. These patients were randomly divided into 2 groups: test group and control group (n = 60, each group). Patients in the test group were treated with JQD, while patients in control group were treated with 5-amino salicylic acid. After treatment for 8 weeks, differences in inflammatory bowel disease questionnaire (IBDQ) scores, short form-36 health survey questionnaire (SF-36) scores, and Sutherland Disease Activity Index (DAI) values were compared between these 2 groups to assess the QOL of patients.Sutherland DAI scores decreased in both groups after the treatment, but the difference was not statistically significant (P < .05). However, the difference in bowel symptoms, systemic symptoms, total scores of the 4 IBDQ dimensions (physical function, bodily pain, vitality, and mental health), and total scores of the SF-36 questionnaires between these 2 groups were statistically significant (P < .05).JQD can be used as supplementary and alternative therapy to relieve clinical symptoms in patients with mild to moderate active UC, and consequently improve their QOL. |
[Mh] Termos MeSH primário: |
Colite Ulcerativa/complicações Colite Ulcerativa/tratamento farmacológico Medicamentos de Ervas Chinesas/uso terapêutico Fármacos Gastrointestinais/uso terapêutico Qualidade de Vida Esplenopatias/complicações
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[Mh] Termos MeSH secundário: |
Adulto Feminino Nível de Saúde Seres Humanos Masculino Saúde Mental Mesalamina/uso terapêutico Meia-Idade Dor/tratamento farmacológico
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[Pt] Tipo de publicação: | JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL |
[Nm] Nome de substância:
| 0 (Drugs, Chinese Herbal); 0 (Gastrointestinal Agents); 0 (jianpi qingre huayu); 4Q81I59GXC (Mesalamine) |
[Em] Mês de entrada: | 1705 |
[Cu] Atualização por classe: | 170509 |
[Lr] Data última revisão:
| 170509 |
[Sb] Subgrupo de revista: | AIM; IM |
[Da] Data de entrada para processamento: | 170420 |
[St] Status: | MEDLINE |
[do] DOI: | 10.1097/MD.0000000000006651 |
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