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[PMID]:28494651
[Au] Autor:Liu F; Chen G; Zhang LH; Liu B; Chen S; Hua H; Bai J; Wang HF; Pei YH
[Ad] Endereço:a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang , China.
[Ti] Título:Isolation and structure elucidation of a new compound from the fungus Aspergillus flavipes PJ03-11.
[So] Source:Nat Prod Res;32(1):30-35, 2018 Jan.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A new diphenyl ether 3-methylpentyl-2, 4-dichloroasterrate (2), along with a known diphenyl ether butyl 2, 4-dichloroasterrate (1) were isolated from the metabolites of a wetland fungus Aspergillus flavipes. PJ03-11. The structures of 1 and 2 were determined by extensive NMR and HR-ESI-MS experiments. Compounds 1 and 2 showed weak cytotoxic activity, but both of them showed no antimicrobial activity.
[Mh] Termos MeSH primário: Anti-Infecciosos/farmacologia
Aspergillus/química
Hidroxibenzoatos/farmacologia
Éteres Fenílicos/farmacologia
[Mh] Termos MeSH secundário: Anti-Infecciosos/química
Antineoplásicos/química
Antineoplásicos/farmacologia
Cristalografia por Raios X
Avaliação Pré-Clínica de Medicamentos/métodos
Células HL-60
Seres Humanos
Hidroxibenzoatos/química
Espectroscopia de Ressonância Magnética
Estrutura Molecular
Éteres Fenílicos/química
Espectrometria de Massas por Ionização por Electrospray
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antineoplastic Agents); 0 (Hydroxybenzoates); 0 (Phenyl Ethers)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1326490


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[PMID]:28468259
[Au] Autor:Han Z; Li YX; Liu LL; Lu L; Guo XR; Zhang XX; Zhang XY; Qi SH; Xu Y; Qian PY
[Ad] Endereço:Institute of Deep-sea Science and Engineering, Chinese Academy of Sciences, 28 Luhuitou Road, Sanya 572000, China. zhuanghan@idsse.ac.cn.
[Ti] Título:Thielavins W-Z7, New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp. UST030930-004.
[So] Source:Mar Drugs;15(5), 2017 Apr 29.
[Is] ISSN:1660-3397
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Eleven new depsides-thielavins W-Z ( - ) and thielavins Z1-Z7 ( - )-and also four known thielavins-A, H, J, and K ( - )-were isolated from the ethyl acetate extract of a marine-derived fungal strain sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle (= ) . The results showed that compounds 1-3 and 6-13 were active, with EC values ranging from 2.95 ± 0.59 to 69.19 ± 9.51 µM, respectively. The inhibitive effect of compounds - and was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.
[Mh] Termos MeSH primário: Organismos Aquáticos/química
Incrustação Biológica/prevenção & controle
Depsídeos/química
Depsídeos/farmacologia
Fungos/química
Hidroxibenzoatos/química
Hidroxibenzoatos/farmacologia
Sordariales/química
[Mh] Termos MeSH secundário: Animais
Thoracica/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Depsides); 0 (Hydroxybenzoates)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE


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[PMID]:29351879
[Au] Autor:Szopa A; Starzec A; Ekiert H
[Ad] Endereço:Chair and Department of Pharmaceutical Botany, Jagiellonian University, Collegium Medicum, ul. Medyczna 9, 30-688 Kraków, Poland. Electronic address: a.szopa@uj.edu.pl.
[Ti] Título:The importance of monochromatic lights in the production of phenolic acids and flavonoids in shoot cultures of Aronia melanocarpa, Aronia arbutifolia and Aronia נprunifolia.
[So] Source:J Photochem Photobiol B;179:91-97, 2018 Feb.
[Is] ISSN:1873-2682
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Shoot cultures of Aronia melanocarpa, A. arbutifolia and A. × prunifolia were maintained on Murashige and Skoog medium with 1 mg/l each of BA and NAA under monochromatic lights (far-red, red, blue lights, UV-A-irradiation), in darkness, and under white light (control). HPLC-DAD analyses of 19 phenolic acids and 11 flavonoids in methanolic extracts from the shoots revealed in all of them the presence of three depsides (chlorogenic, neochlorogenic and rosmarinic acids), protocatechuic acid, four flavonoid glycosides (cynaroside, quercitrin, hyperoside and rutoside), and additionally, in A. arbutifolia, 3,4-dihydroxyphenylacetic acid. Depending on light quality, the total amounts of these metabolites increased 1.8-5.9 times, reaching maximum values under blue light: 527.40 and 144.61 mg 100 g DW (A. melanocarpa), 543.27 and 85.82 mg 100 g DW (A. arbutifolia) and 1615.18 and 220.65 mg 100 g DW (A. × prunifolia), respectively. The maximum total amounts were 1.3-3.6 times higher than under white light. The quantities of individual metabolites changed from 1.2 to 11.0 times, with high amounts of neochlorogenic acid and quercitrin in A. melanocarpa (243.35 and 75.64 mg 100 g DW), and of chlorogenic and rosmarinic acids and quercitrin in A. arbutifolia (236.52, 219.35 and 51.01 mg 100 g DW). Extremely high amounts of depsides (418.83, 644.68, 548.86 mg 100 g DW) and quercitrin (165.88 mg 100 g DW) were produced in cultures of the hybrid - A. × prunifolia. The results are potentially useful for practical applications. This is the first report documented the importance of light quality on the production of phenolic acids and flavonoids in three aronia in vitro cultures.
[Mh] Termos MeSH primário: Flavonoides/metabolismo
Hidroxibenzoatos/metabolismo
Luz
Photinia/efeitos da radiação
[Mh] Termos MeSH secundário: Biomassa
Ácido Clorogênico/análise
Ácido Clorogênico/metabolismo
Cromatografia Líquida de Alta Pressão
Cinamatos/análise
Cinamatos/metabolismo
Depsídeos/análise
Depsídeos/metabolismo
Flavonoides/análise
Hidroxibenzoatos/análise
Photinia/química
Photinia/metabolismo
Brotos de Planta/química
Brotos de Planta/metabolismo
Brotos de Planta/efeitos da radiação
Quercetina/análogos & derivados
Quercetina/análise
Quercetina/metabolismo
Raios Ultravioleta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cinnamates); 0 (Depsides); 0 (Flavonoids); 0 (Hydroxybenzoates); 29656-58-4 (phenolic acid); 2Y8906LC5P (quercitrin); 318ADP12RI (Chlorogenic Acid); 9IKM0I5T1E (Quercetin); MQE6XG29YI (rosmarinic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180121
[St] Status:MEDLINE


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[PMID]:29179063
[Au] Autor:Gao X; Mu J; Guan S; Li Q; Du Y; Zhang H; Bi K
[Ad] Endereço:School of Chinese Traditional Medicine, Shenyang Pharmaceutical University, 103Wenhua Road, Shenyang 110016, China.
[Ti] Título:Simultaneous determination of phenolic acids and diterpenoids and their comparative pharmacokinetic study in normal and acute blood stasis rats by UFLC-MS/MS after oral administration of Guan-Xin-Shu-Tong capsules.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1072:221-228, 2018 Jan 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Guan-Xin-Shu-Tong capsules are one of the well-known and first-line Chinese traditional herbal formula for treating coronary heart disease. A validated and sensitive method via ultra fast liquid chromatography-tandem mass spectrometry (UFLC-MS/MS) was established to simultaneously determinate five phenolic acids and four diterpenoids in rats in order to investigate their pharmacokinetic profiles firstly. Analytes were extracted by ethyl acetate and determined via multiple reaction monitoring mode in both positive and negative ion modes. The values for limit of quantification were in range of 0.025-1.250ng/ml. Inter- and intra-day precisions were no more than 10.9% with accuracy of -11.0%-10.6%, meanwhile the stable and suitable extraction recoveries were also obtained. And finally such excellent method was used to compare the pharmacokinetics of nine compounds in normal and acute blood stasis rats after oral administration of Guan-Xin-Shu-Tong capsules.
[Mh] Termos MeSH primário: Cromatografia Líquida de Alta Pressão/métodos
Diterpenos/sangue
Medicamentos de Ervas Chinesas/administração & dosagem
Hidroxibenzoatos/sangue
Espectrometria de Massas em Tandem/métodos
[Mh] Termos MeSH secundário: Animais
Diterpenos/química
Diterpenos/farmacocinética
Medicamentos de Ervas Chinesas/farmacocinética
Hidroxibenzoatos/química
Hidroxibenzoatos/farmacocinética
Modelos Lineares
Ratos
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Diterpenes); 0 (Drugs, Chinese Herbal); 0 (Hydroxybenzoates); 29656-58-4 (phenolic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


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[PMID]:28749671
[Au] Autor:Xu L; Wu P; Xue J; Molnar I; Wei X
[Ad] Endereço:Key Laboratory of Plant Resources Conservation and Sustainable Utilization/Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences , Guangzhou 510650, People's Republic of China.
[Ti] Título:Antifungal and Cytotoxic ß-Resorcylic Acid Lactones from a Paecilomyces Species.
[So] Source:J Nat Prod;80(8):2215-2223, 2017 Aug 25.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Eight new ß-resorcylic acid lactones (RALs), including the hypothemycin-type compounds paecilomycins N-P (1-3) and the radicicol-type metabolites dechloropochonin I (4), monocillins VI (5) and VII (6), 4'-hydroxymonocillin IV (7), and 4'-methoxymonocillin IV (8), along with nine known RALs (9-17), were isolated from the cultures of Paecilomyces sp. SC0924. Compounds 1 and 2 feature a novel 6/11/5 ring system, and 3 is the first 5'-keto RAL. The structures of 1-8 were elucidated on the basis of extensive spectroscopic analysis, X-ray diffraction analysis, and theoretical calculations of ECD spectra. Compounds 3, 5, and 6 exhibit cytotoxicity against MCF-7, A549, and HeLa cells, and compounds 5 and 7 display antifungal activity against Peronophythora litchii.
[Mh] Termos MeSH primário: Éteres de Hidroxibenzoatos/isolamento & purificação
Éteres de Hidroxibenzoatos/farmacologia
Hidroxibenzoatos/isolamento & purificação
Hidroxibenzoatos/farmacologia
Lactonas/isolamento & purificação
Lactonas/farmacologia
Macrolídeos/farmacologia
Paecilomyces/química
Phytophthora/química
Zearalenona/análogos & derivados
[Mh] Termos MeSH secundário: Antifúngicos
Células HeLa
Seres Humanos
Éteres de Hidroxibenzoatos/química
Hidroxibenzoatos/química
Lactonas/química
Macrolídeos/química
Estrutura Molecular
Difração de Raios X
Zearalenona/química
Zearalenona/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Hydroxybenzoate Ethers); 0 (Hydroxybenzoates); 0 (Lactones); 0 (Macrolides); 0 (hypothemycin); 0 (paecilomycin-N); 0 (paecilomycin-O); 0 (paecilomycin-P); 5W827M159J (Zearalenone); I60EH8GECX (monorden); LU39SC9JYL (beta-resorcylic acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170728
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00066


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[PMID]:28467350
[Au] Autor:Santos HFD; Campos JF; Santos CMD; Balestieri JBP; Silva DB; Carollo CA; de Picoli Souza K; Estevinho LM; Dos Santos EL
[Ad] Endereço:Research group on Biotechnology and Bioprospecting Applied to Metabolism (GEBBAM), Federal University of Grande Dourados, Rodovia Dourados Itahum, Km 12, 79804-970 Dourados, MS, Brazil. helderspk@gmail.com.
[Ti] Título:Chemical Profile and Antioxidant, Anti-Inflammatory, Antimutagenic and Antimicrobial Activities of Geopropolis from the Stingless Bee Melipona orbignyi.
[So] Source:Int J Mol Sci;18(5), 2017 May 03.
[Is] ISSN:1422-0067
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Geopropolis is a resin mixed with mud, produced only by stingless bees. Despite being popularly known for its medicinal properties, few scientific studies have proven its biological activities. In this context, the objective of this study was to determine the chemical composition and antioxidant, anti-inflammatory, antimutagenic and antimicrobial activities of the geopropolis. The hydroalcoholic extract of geopropolis (HEGP) was prepared and its chemical composition determined by high performance liquid chromatography coupled to diode array detector and mass spectrometry (HPLC-DAD-MS). The antioxidant activity was determined by the capture of free radicals and inhibition of lipid peroxidation in human erythrocytes. The anti-inflammatory activity was evaluated by the inhibition of the hyaluronidase enzyme and the antimutagenic action was investigated in colonies. The antimicrobial activities were determined against bacteria and yeasts, isolated from reference strains and hospital origin. The chemical composition of HEGP included flavonoids, derivatives of glycosylated phenolic acids and terpenoids. HEGP showed high antioxidant activity, it inhibited the activity of the inflammatory enzyme hyaluronidase and reduced the mutagenic effects in . In relation to the antimicrobial activity, it promoted the death of all microorganisms evaluated. In conclusion, this study reveals for the first time the chemical composition of the HEGP of and demonstrates its pharmacological properties.
[Mh] Termos MeSH primário: Anti-Infecciosos
Anti-Inflamatórios
Antioxidantes
Abelhas/química
Própole
[Mh] Termos MeSH secundário: Animais
Anti-Infecciosos/química
Anti-Infecciosos/farmacologia
Anti-Inflamatórios/química
Anti-Inflamatórios/farmacologia
Antioxidantes/química
Antioxidantes/farmacologia
Bactérias/efeitos dos fármacos
Cromatografia Líquida de Alta Pressão
Eritrócitos/efeitos dos fármacos
Metanossulfonato de Etila/farmacologia
Flavonoides/análise
Radicais Livres/análise
Seres Humanos
Hialuronoglucosaminidase/efeitos dos fármacos
Hidroxibenzoatos/análise
Peroxidação de Lipídeos/efeitos dos fármacos
Espectrometria de Massas
Mutagênicos
Própole/química
Própole/farmacologia
Saccharomyces cerevisiae/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Anti-Inflammatory Agents); 0 (Antioxidants); 0 (Flavonoids); 0 (Free Radicals); 0 (Hydroxybenzoates); 0 (Mutagens); 29656-58-4 (phenolic acid); 9009-62-5 (Propolis); 9H154DI0UP (Ethyl Methanesulfonate); EC 3.2.1.35 (Hyaluronoglucosaminidase)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE


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[PMID]:29257652
[Au] Autor:Ganie AH; Yousuf PY; Ahad A; Pandey R; Ahmad S; Aref IM; Noor JJ; Iqbal M
[Ti] Título:Quantification of phenolic acids and antioxidant potential of inbred, hybrid and composite cultivars of maize under different nitrogen regimes.
[So] Source:J Environ Biol;37(6):1273-79, 2016 Nov.
[Is] ISSN:0254-8704
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:Maize (Zea mays L.) is a multipurpose crop, which is immensely used worldwide for its nutritional as well as medicinal properties. This study evaluates the effect of varying concentrations of nitrogen (N) on accumulation of phenolic acids and antioxidant activity in different maize cultivars, including inbreds, hybrids and a composite, which were grown in natural light under controlled temperature (30°C/20°C D/N) and humidity (80%), with sufficient (4.5mM) and low (0.05mM) nitrogen supply. Seeds of different cultivars were powdered and extracted in a methanol:water (80:20) mixture through reflux at 60-75°C, and the extracts obtained were subjected to high performance thin layer chromatography (HPTLC), using ethyl acetate: acetic acid: formic acid: water (109:16:12:31) solvent system for the separation of phenolic acids. Antioxidant activity of the extracts was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and H2O2-scavenging activity assays. At sufficient nitrogen condition, the contents of different phenolic acids were higher in the composite cultivar (8.7 mg g-1 d.wt. in gallic acid to 39.3 mg g-1 d.wt. in cinnamic and salicylic acids) than in inbreds and hybrids. Under low nitrogen condition, the phenolic acids contents declined significantly in inbreds and hybrids, but remained almost unaffected in the composite. The antioxidant activity was also the maximum in the composite, and declined similarly as phenolic acids under low nitrogen supply, showing a significant reduction in inbreds and hybrids only. Therefore, the maize composite has a potential for being used as a nutraceutical in human-health sector.
[Mh] Termos MeSH primário: Antioxidantes/metabolismo
Hidroxibenzoatos/metabolismo
Nitrogênio/farmacologia
Zea mays/genética
Zea mays/fisiologia
[Mh] Termos MeSH secundário: Antioxidantes/química
Cruzamentos Genéticos
Hidroxibenzoatos/química
Endogamia
Zea mays/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antioxidants); 0 (Hydroxybenzoates); 29656-58-4 (phenolic acid); N762921K75 (Nitrogen)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171220
[St] Status:MEDLINE


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[PMID]:29381315
[Au] Autor:Bazamova YG; Ivanchenko OB
[Ti] Título:[Investigation of the composition of biologically active substances in extracts of wild plants].
[So] Source:Vopr Pitan;85(5):100-7, 2016.
[Is] ISSN:0042-8833
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article presents the research materials of composition and the properties of biologically active compounds of aqueous ethanolic extracts of wild plants. To obtain extracts, we used raw plants containing phenolic compounds and aromatic wild plants: the herb St. John's wort (Hypericum), thyme herba (Thymus vulgaris), yarrow (Achillea millefolium), oregano (Origanum vulgaris); leaves of sage (Salviae folium); rose hips (Rosae), hawthorn fructus (Crataegus) and fruits of mountain ash (Sorbus). The optimum composition of the mixtures used and time of extraction has been established: the ratio of alcohol and water in extracting mixtures 1:1 by volume; ratio raw material:extractant - 1:7 by weight. The total content of fenolic substances in extracts of herbaceous plants varied from to 15.5 to 24.4 mg/g, and in fruit extracts from 24.2 to 29.7 mg/g. Substances of phenolic nature, including gallic and ferulic acid, rutin, hesperidin, quercetin and apigenin were identified in the studied extracts using the HPLC. The analysis of flavonoid composition showed that rutin content in the investigated extracts varied from 0.56 mg/g up to 13,80 mg/g, of quercetin - from 0.52 to 1.36 mg/g; apigenin - from 0.44 to 1.44 mg/g; hesperidin from 2.44 to 32,72 mg/g. The content of phenolic acids varied from 0.16 to 1.44 mg/g (ferulic acid) and from 0.16 to 3.12 mg/g (chlorogenic acid). Total antioxidant activity of the studied phytoextracts (dilution 1:10) ranged from 142 to 230 µg/ml (in terms of ascorbic acid), which is consistent with the results of the quantitative analysis of flavonoids. The results of the studies of antimicrobial properties of phytoextracts showed that for E. coli the most active extracts were from thyme and yarrow, and against S. aureus - from St. John's wort. Extracts of St. John's wort and yarrow were effective against Rhizopus stolonifer.
[Mh] Termos MeSH primário: Anti-Infecciosos/análise
Antioxidantes/análise
Flavonoides/análise
Hidroxibenzoatos/análise
Extratos Vegetais/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Antioxidants); 0 (Flavonoids); 0 (Hydroxybenzoates); 0 (Plant Extracts); 29656-58-4 (phenolic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180131
[St] Status:MEDLINE


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[PMID]:29262714
[Au] Autor:Karadag B; Yücel NC
[Ad] Endereço:Department of Chemistry, Faculty of Science, Dokuz Eylul University , Buca, 35390, Izmir , Turkey.
[Ti] Título:Cinnamic acid and fish flour affect wheat phenolic acids and flavonoid compounds, lipid peroxidation, proline levels under salt stress.
[So] Source:Acta Biol Hung;68(4):388-397, 2017 Dec.
[Is] ISSN:0236-5383
[Cp] País de publicação:Hungary
[La] Idioma:eng
[Ab] Resumo:To elucidate the physiological mechanism of salt stress mitigated by cinnamic acid (CA) and fish flour (FF) pretreatment, wheat was pretreated with 20, 50 and 100 ppm CA and 1 g/10 mL FF for 2 d and was then cultivated. We investigated whether exogenous CA + FF could protect wheat from salt stress and examined whether the protective effect was associated with the regulation of seed vigor, antioxidant defense systems, phenolic biosynthesis and lipid peroxidation. At 2 days exogenous CA did not influence seed vigor. Salt stress increased the phenolic biosynthesis, but the CA + FF-combined pretreatment enhanced the phenolic biosynthesis even more under salt stress and decreased lipid peroxidation to some extent, enhancing the tolerance of wheat to salt stress.
[Mh] Termos MeSH primário: Cinamatos/metabolismo
Farinha de Peixe
Flavonoides/metabolismo
Hidroxibenzoatos/metabolismo
Peroxidação de Lipídeos
Pressão Osmótica
Triticum/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cinnamates); 0 (Flavonoids); 0 (Hydroxybenzoates); 29656-58-4 (phenolic acid); U14A832J8D (cinnamic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180216
[Lr] Data última revisão:
180216
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171222
[St] Status:MEDLINE
[do] DOI:10.1556/018.68.2017.4.5


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[PMID]:29364608
[Ti] Título:[Not Available.]
[So] Source:Mikrobiologiia;85(5):609-612, 2016 Sep.
[Is] ISSN:0026-3656
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Mh] Termos MeSH primário: Proteínas de Bactérias/metabolismo
Catecol 1,2-Dioxigenase/metabolismo
Catecóis/metabolismo
Hidroxibenzoatos/farmacologia
Rhodococcus/efeitos dos fármacos
[Mh] Termos MeSH secundário: Proteínas de Bactérias/genética
Proteínas de Bactérias/isolamento & purificação
Catecol 1,2-Dioxigenase/genética
Catecol 1,2-Dioxigenase/isolamento & purificação
Catecóis/química
Ativação Enzimática/efeitos dos fármacos
Ensaios Enzimáticos
Expressão Gênica
Cinética
Rhodococcus/enzimologia
Rhodococcus/genética
Frações Subcelulares/química
Frações Subcelulares/metabolismo
Especificidade por Substrato
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Catechols); 0 (Hydroxybenzoates); 2ZFW40OJ7U (3-hydroxybenzoic acid); EC 1.13.11.1 (Catechol 1,2-Dioxygenase)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE



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