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Pesquisa : D02.455.326.146.100.050 [Categoria DeCS]
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[PMID]:28743395
[Au] Autor:Munoz G; Labadie P; Geneste E; Pardon P; Tartu S; Chastel O; Budzinski H
[Ad] Endereço:University of Bordeaux, EPOC, UMR 5805, LPTC Research Group, Talence F-33400, France.
[Ti] Título:Biomonitoring of fluoroalkylated substances in Antarctica seabird plasma: Development and validation of a fast and rugged method using on-line concentration liquid chromatography tandem mass spectrometry.
[So] Source:J Chromatogr A;1513:107-117, 2017 Sep 01.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We report on a fast, accurate and rugged analytical procedure to determine a wide span of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in seabird plasma. The 26 investigated compounds included perfluoroalkyl carboxylates (C -C PFCAs), perfluoroalkyl sulfonates (C , C , C , C , C PFSAs), perfluorooctane sulfonamide (FOSA) and N-alkyl derivatives (MeFOSA, EtFOSA), N-alkyl perfluorooctane sulfonamido acetic acids (MeFOSAA, EtFOSAA), fluorotelomer sulfonates (4:2 FTSA, 6:2 FTSA, 8:2 FTSA), polyfluoroalkyl phosphate diesters (diPAPs) and perfluorooctane sulfonamide phosphate diester (diSAmPAP). The method described herein requires a reduced sample amount (25µL) and involves rapid and simple sample preparation (protein precipitation with acetonitrile but without acidification) prior to analysis by on-line solid phase extraction (Oasis HLB sorbent) coupled to high performance liquid chromatography negative electrospray ionization tandem mass spectrometry. The optimization was conducted using experimental designs to account for potential interactions between variables. Out of the 26 target analytes, 23 compounds showed excellent accuracy (±25% of the expected values). Intermediate precision and matrix effects remained acceptable for most analytes thanks to efficient internal standardization. A human serum standard reference material (NIST SRM 1957) was included in the validation scheme to evaluate method trueness, which proved satisfactory (│Z-scores│<2 for most compounds). Notwithstanding the small initial sample intake, limits of detection as low as 0.003-0.1ngg plasma were obtained. This allowed the determination of 11 target PFASs in Antarctic seabird plasma samples. ΣPFASs in Antarctic seabird plasma ranged from 0.37 to 19ngg , with a predominance of PFOS (>54% of ΣPFASs on average). The reduced plasma amount required implies that the present method could also be applied to the analysis of PFASs in the plasma of smaller biological models.
[Mh] Termos MeSH primário: Alcanossulfonatos/sangue
Charadriiformes/sangue
Monitoramento Ambiental/métodos
Sistemas On-Line
Espectrometria de Massas em Tandem/métodos
[Mh] Termos MeSH secundário: Alcanossulfonatos/análise
Animais
Regiões Antárticas
Calibragem
Cromatografia Líquida de Alta Pressão/métodos
Fluorcarbonetos/sangue
Limite de Detecção
Oceanos e Mares
Extração em Fase Sólida
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Fluorocarbons); 6P60ZBK0QL (perfluorooctane)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171204
[Lr] Data última revisão:
171204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE


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[PMID]:28626132
[Au] Autor:Maurad ZA; Idris Z; Ghazali R
[Ad] Endereço:Advanced Oleochemical Technology Division.
[Ti] Título:Performance of Palm-Based C Methyl Ester Sulphonate (MES) in Liquid Detergent Formulation.
[So] Source:J Oleo Sci;66(7):677-687, 2017 Jul 01.
[Is] ISSN:1347-3352
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Liquid detergents are more convenient than powdered detergents as they dissolve readily in water, generate less dust and dosing is easy. However, the stability of liquid detergents is an issue of concern. Therefore, the objective of this research is to study the formulation requirement to produce heavy-duty liquid detergents based on palm-based methyl esters sulphonate (MES) with desirable properties and performance. MES is produced from renewable and sustainable feedstock suitable to replace the conventional fossil-based surfactant, linear alkyl benzene sulphonates (LAS). Five palm-based liquid detergents (PBLDs) were formulated using C MES as the primary surfactant. The physical properties, washing performance, stability and biodegradability of PBLDs were evaluated. Performance of the PBLDs was evaluated against two commercial liquid detergents which use LAS and alcohol glucoside as surfactant (benchmark product) and it was found that the PBLDs exhibited excellent performance. PBLDs can be formulated with or without phosphates and still demonstrate good detergency. The stability study of PBLDs indicated that no appreciable hydrolysis occurred. PBLDs exhibited better biodegradability profiles compared to commercial detergent containing LAS. PBLDs passed the 60% biodegradability level within 3 to 8 d, while commercial detergent took 24 d. It was shown that palm-based C MES could be potentially formulated into liquid detergents and gave better performance than LAS based liquid detergent. Attributes of C MES should not be overlooked, which include an abundant and naturally derived palm stearin as raw material and environmental safety profiles that are superior to most synthetic surfactants.
[Mh] Termos MeSH primário: Alcanossulfonatos/química
Detergentes/química
Ésteres/química
Óleos Vegetais/química
[Mh] Termos MeSH secundário: Biodegradação Ambiental
Fenômenos Químicos
Química Farmacêutica
Estabilidade de Medicamentos
Óleo de Palmeira
Pós
Tensoativos
Fatores de Tempo
Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Detergents); 0 (Esters); 0 (Plant Oils); 0 (Powders); 0 (Surface-Active Agents); 059QF0KO0R (Water); 5QUO05548Z (Palm Oil)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess16190


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[PMID]:28479068
[Au] Autor:Bergmann ML; Sadjadi S; Schmedes A
[Ad] Endereço:Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark. Electronic address: marianne.bergmann@rsyd.dk.
[Ti] Título:Analysis of catecholamines in urine by unique LC/MS suitable ion-pairing chromatography.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;1057:118-123, 2017 Jul 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The catecholamines, epinephrine (E) and norepinephrine (NE) are small polar, hydrophilic molecules, posing significant challenges to liquid chromatography - tandem mass spectrometry (LC-MS/MS) method development. Specifically, these compounds show little retention on conventional reversed-phase liquid chromatography columns. This work presents development and validation of an LC-MS/MS method for determining catecholamines in urine, based on a new approach to ion-pairing chromatography (IPC), in which the ion-pairing reagent (IPR), 1-Heptane Sulfonic Acid (HSA), is added to the extracted samples instead of the mobile phases. A Hamilton STARlet workstation carried out the solid phase extraction of urine samples. The extracted samples were diluted with 60mmol/L HSA and injected on a Kinetex core-shell biphenyl column with conventional LC-MS/MS suitable mobile phases. Chromatographic separation of E and NE was achieved successfully with very stable retention times (RT). In 484 injections, the RTs were steady with a CV of less than ±4%. Furthermore, HSA was separated from E and NE, allowing HSA to be diverted to waste instead of entering the mass spectrometer ion chamber. The method was validated with good analytical performance, and even though the analysis for urinary catecholamines is increasingly being replaced by plasma free metanephrines in diagnosing pheochromocytomas, this work represents the application of a new analytical technique that can be transferred to other small polar molecules, that are difficult to chromatograph on traditional reversed phase columns.
[Mh] Termos MeSH primário: Cromatografia Líquida de Alta Pressão/métodos
Epinefrina/urina
Norepinefrina/urina
Espectrometria de Massas em Tandem/métodos
[Mh] Termos MeSH secundário: Alcanossulfonatos
Calibragem
Cromatografia de Fase Reversa
Seres Humanos
Interações Hidrofóbicas e Hidrofílicas
Extração Líquido-Líquido
Propriedades de Superfície
[Pt] Tipo de publicação:JOURNAL ARTICLE; VALIDATION STUDIES
[Nm] Nome de substância:
0 (1-heptanesulfonic acid); 0 (Alkanesulfonates); X4W3ENH1CV (Norepinephrine); YKH834O4BH (Epinephrine)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170718
[Lr] Data última revisão:
170718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170509
[St] Status:MEDLINE


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[PMID]:28187362
[Au] Autor:Shi G; Cui Q; Pan Y; Sheng N; Sun S; Guo Y; Dai J
[Ad] Endereço:Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, PR China.
[Ti] Título:6:2 Chlorinated polyfluorinated ether sulfonate, a PFOS alternative, induces embryotoxicity and disrupts cardiac development in zebrafish embryos.
[So] Source:Aquat Toxicol;185:67-75, 2017 Apr.
[Is] ISSN:1879-1514
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:As an alternative to perfluorooctanesulfonate (PFOS), 6:2 chlorinated polyfluorinated ether sulfonate (commercial name: F-53B) has been used as a mist suppressant in Chinese electroplating industries for over 30 years. It has been found in the environment and fish, and one acute assay indicated F-53B was moderately toxic. However, the toxicological information on this compound was incomplete and insufficient for assessment of their environment impact. The object of this study was to examine the developmental toxicity of F-53B using zebrafish embryos. Zebrafish embryos were incubated in 6-well plates with various concentrations of F-53B (1.5, 3, 6, and 12mg/L) from 6 to 132h post fertilization (hpf). Results showed that F-53B exposure induced developmental toxicity, including delayed hatching, increased occurrence of malformations, and reduced survival. Malformations, including pericardial and yolk sac edemas, abnormal spines, bent tails, and uninflated swim bladders, appeared at 84 hpf, and increased with time course and dose. A decrease in survival percentages was noted in the 6 and 12mg/L F-53B-treated groups at 132 hpf. Continuous exposure to 3mg/L F-53B resulted in high accumulation levels in zebrafish embryos, suggesting an inability for embryos to eliminate this compound and a high cumulative risk to fish. We also examined the cardiac function of embryos at specific developmental stages following exposure to different concentrations, and found that F-53B induced cardiac toxicity and reduced heart rate. Even under low F-53B concentration, o-dianisidine staining results showed significant decrease of relative erythrocyte number at 72 hpf before the appearance of observed effects of F-53B on the heart. To elucidate the underlying molecular changes, genes involved in normal cardiac development were analyzed using real-time qPCR in the whole-body of zebrafish embryos. F-53B inhibited the mRNA expression of ß-catenin (ctnnb2) and wnt3a. The mRNA levels of ß-catenin targeted genes (nkx2.5 and sox9b), which play critical roles in cardiogenesis, were also reduced after exposure. Thus, exposure to F-53B impaired the development of zebrafish embryos and disrupted cardiac development, which might be mediated by effects on the Wnt signaling pathway and decrease of erythrocyte numbers.
[Mh] Termos MeSH primário: Alcanossulfonatos/toxicidade
Ácidos Alcanossulfônicos/toxicidade
Embrião não Mamífero/efeitos dos fármacos
Fluorcarbonetos/toxicidade
Coração/embriologia
Peixe-Zebra/embriologia
[Mh] Termos MeSH secundário: Alcanossulfonatos/química
Ácidos Alcanossulfônicos/química
Animais
Embrião não Mamífero/metabolismo
Eritrócitos/efeitos dos fármacos
Fluorcarbonetos/química
Regulação da Expressão Gênica no Desenvolvimento/efeitos dos fármacos
Coração/efeitos dos fármacos
Larva/efeitos dos fármacos
RNA Mensageiro/genética
RNA Mensageiro/metabolismo
Poluentes Químicos da Água/toxicidade
Peixe-Zebra/genética
Proteínas de Peixe-Zebra/genética
Proteínas de Peixe-Zebra/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (2-((6-chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)oxy)-1,1,2,2-tetrafluoroethanesulfonic acid); 0 (Alkanesulfonates); 0 (Alkanesulfonic Acids); 0 (Fluorocarbons); 0 (RNA, Messenger); 0 (Water Pollutants, Chemical); 0 (Zebrafish Proteins); 9H2MAI21CL (perfluorooctane sulfonic acid)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE


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[PMID]:28082224
[Au] Autor:Zhang H; Bai Y; Zhou W; Chen F
[Ad] Endereço:State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, Guangdong, China.
[Ti] Título:Color reduction of sulfonated eucalyptus kraft lignin.
[So] Source:Int J Biol Macromol;97:201-208, 2017 Apr.
[Is] ISSN:1879-0003
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Several eucalyptus lignins named as HSL, SML and BSL were prepared by high temperature sulfonation, sulfomethylation, butane sultone sulfonation respectively. The color properties of samples were investigated. Under optimized conditions the sulfonic group (SO H) content of HSL, SML and BSL reached 1.52, 1.60 and 1.58mmol/g, respectively. Samples were characterized by UV-vis spectroscopy, FTIR spectroscopy, H NMR spectroscopy, GPC and brightness test, respectively. The results revealed that BSL performed a higher molecular weight and lighter color due to the phenolic hydroxyl blocking by 1,4-butane sultone (1,4-BS). The color reduction of sodium borohydride treated BSL (labeled as SBSL) was further enhanced and the brightness value was improved by 76.1% compared with the darkest HSL. SBSL process was much better than HSL and SML process. Hydroxyl blocking effect of 1,4-BS and reducibility of sodium borohydride played important roles in the color reduction of sulfonated eucalyptus kraft lignin.
[Mh] Termos MeSH primário: Alcanossulfonatos/química
Eucalyptus/química
Lignina/química
[Mh] Termos MeSH secundário: Boroidretos/química
Cor
Peso Molecular
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Borohydrides); 1633-83-6 (butanesultone); 8068-05-1 (Kraft lignin); 87L0B9CPPA (sodium borohydride); 9005-53-2 (Lignin)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170410
[Lr] Data última revisão:
170410
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170114
[St] Status:MEDLINE


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[PMID]:28055215
[Au] Autor:Qi X; Wei W; Li J; Zuo G; Pan X; Su T; Zhang J; Dong W
[Ad] Endereço:Center for Molecular Metabolism, Nanjing University of Science & Technology , Nanjing 210094, China.
[Ti] Título:Salecan-Based pH-Sensitive Hydrogels for Insulin Delivery.
[So] Source:Mol Pharm;14(2):431-440, 2017 Feb 06.
[Is] ISSN:1543-8392
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Stimuli-responsive polymeric hydrogels are promising and appealing delivery vehicles for protein/peptide drugs and have made protein/peptide delivery with both dosage- and spatiotemporal-controlled manners possible. Here a series of new Salecan-based pH-sensitive hydrogels were fabricated for controlled insulin delivery via the graft copolymerization reaction between Salecan and 2-acrylamido-2-methyl-1-propanesulfonic acid. In this study, on one hand, Salecan played a key role in modifying the structure and the pore size of the developing hydrogel. On the other hand, Salecan tuned the water content and the water release rate of the obtained hydrogel, leading to a controllable release rate of the insulin. More importantly, in vitro release experiments validated that the release of insulin from this intelligent system could be also tailored by the environmental pH of the release medium. For SGA2, the amount of encapsulated insulin released at gastric conditions (pH 1.2) was relatively low (about 26.1 wt % in 24 h), while that released at intestinal conditions (pH 7.4) increased significantly (over 50 wt % in 6 h). Furthermore, toxicity assays demonstrated that the designed hydrogel carriers were biocompatible. These characteristics make the Salecan-based hydrogel a promising candidate for protein/peptide drug delivery device.
[Mh] Termos MeSH primário: Hidrogéis/química
Insulina/química
beta-Glucanas/química
[Mh] Termos MeSH secundário: Acrilamidas/química
Alcanossulfonatos/química
Animais
Células COS
Linhagem Celular
Portadores de Fármacos/química
Sistemas de Liberação de Medicamentos/métodos
Excipientes/química
Células HEK293
Seres Humanos
Concentração de Íons de Hidrogênio
Polímeros/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acrylamides); 0 (Alkanesulfonates); 0 (Drug Carriers); 0 (Excipients); 0 (Hydrogels); 0 (Insulin); 0 (Polymers); 0 (beta-Glucans); 0 (salecan); 490HQE5KI5 (2-acrylamido-2-methylpropanesulfonate)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170106
[St] Status:MEDLINE
[do] DOI:10.1021/acs.molpharmaceut.6b00875


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[PMID]:28006759
[Au] Autor:Beskoski VP; Yamamoto K; Yamamoto A; Okamura H; Hayashi M; Nakano T; Matsumura C; Fukushi K; Wada S; Inui H
[Ad] Endereço:University of Belgrade, Faculty of Chemistry, P.O. Box 51, Belgrade, Serbia; Research Center for Environmental Genomics, Kobe University, 1-1 Rokkodaicho, Nada-ku, Kobe, Hyogo 657-8501, Japan. Electronic address: vbeskoski@chem.bg.ac.rs.
[Ti] Título:Distribution of perfluoroalkyl compounds in Osaka Bay and coastal waters of Western Japan.
[So] Source:Chemosphere;170:260-265, 2017 Mar.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Perfluoroalkyl acids (PFAAs) including perfluoroalkyl sulfonates (PFSAs) and perfluoroalkyl carboxylates (PFCAs) were analyzed in sediment samples taken from Ajifu Waterway in Osaka city, from Osaka Bay, and from Kagoshima Bay, as well as in fifteen seawater samples collected from Osaka Bay and coastal waters of Western Japan. In all sediment samples, only PFCAs were detected, and the highest concentration was determined in Ajifu Waterway, where ΣPFAA was 58990 ng kg dry weight. The total concentrations of PFAAs in sea water samples ranged between the limit of quantification and 53.4 ng L , and perfluorohexanoic acid was the most prevalent and had the highest concentration of 37 ng L . The changes in the patterns and concentrations of PFAAs in Osaka Bay and coastal waters of Western Japan indicate that the PFAAs in surface waters are influenced by sources from Keihanshin Metropolitan Area, mainly the Yodo River basin, and the dilution effect which naturally occurs during their transport to the Pacific Ocean.
[Mh] Termos MeSH primário: Alcanossulfonatos/análise
Caproatos/análise
Monitoramento Ambiental/métodos
Fluorcarbonetos/análise
Rios/química
Água do Mar/química
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Baías
Cidades
Japão
Oceano Pacífico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Caproates); 0 (Fluorocarbons); 0 (Water Pollutants, Chemical); ZP34Q2220R (perfluorohexanoic acid)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161223
[St] Status:MEDLINE


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[PMID]:28000448
[Au] Autor:Buchanan MK; Needham CN; Neill NE; White MC; Kelly CB; Mastro-Kishton K; Chauvigne-Hines LM; Goodwin TJ; McIver AL; Bartolotti LJ; Frampton AR; Bourdelais AJ; Varadarajan S
[Ad] Endereço:Department of Chemistry and Biochemistry, University of North Carolina Wilmington , Wilmington, North Carolina 28403, United States.
[Ti] Título:Glycoconjugated Site-Selective DNA-Methylating Agent Targeting Glucose Transporters on Glioma Cells.
[So] Source:Biochemistry;56(2):421-440, 2017 Jan 17.
[Is] ISSN:1520-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:DNA-alkylating drugs continue to remain an important weapon in the arsenal against cancers. However, they typically suffer from several shortcomings because of the indiscriminate DNA damage that they cause and their inability to specifically target cancer cells. We have developed a strategy for overcoming the deficiencies in current DNA-alkylating chemotherapy drugs by designing a site-specific DNA-methylating agent that can target cancer cells because of its selective uptake via glucose transporters, which are overexpressed in most cancers. The design features of the molecule, its synthesis, its reactivity with DNA, and its toxicity in human glioblastoma cells are reported here. In this molecule, a glucosamine unit, which can facilitate uptake via glucose transporters, is conjugated to one end of a bispyrrole triamide unit, which is known to bind to the minor groove of DNA at A/T-rich regions. A methyl sulfonate moiety is tethered to the other end of the bispyrrole unit to serve as a DNA-methylating agent. This molecule produces exclusively N3-methyladenine adducts upon reaction with DNA and is an order of magnitude more toxic to treatment resistant human glioblastoma cells than streptozotocin is, a Food and Drug Administration-approved, glycoconjugated DNA-methylating drug. Cellular uptake studies using a fluorescent analogue of our molecule provide evidence of uptake via glucose transporters and localization within the nucleus of cells. These results demonstrate the feasibility of our strategy for developing more potent anticancer chemotherapeutics, while minimizing common side effects resulting from off-target damage.
[Mh] Termos MeSH primário: Antineoplásicos Alquilantes/síntese química
Adutos de DNA/biossíntese
DNA de Neoplasias/antagonistas & inibidores
Proteínas Facilitadoras de Transporte de Glucose/metabolismo
Glicoconjugados/síntese química
Neuroglia/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adenina/análogos & derivados
Adenina/química
Adenina/metabolismo
Alcanossulfonatos/química
Antineoplásicos Alquilantes/metabolismo
Antineoplásicos Alquilantes/farmacologia
Transporte Biológico
Linhagem Celular Tumoral
Sobrevivência Celular/efeitos dos fármacos
Adutos de DNA/química
Dano ao DNA
Metilação de DNA
DNA de Neoplasias/química
DNA de Neoplasias/metabolismo
Expressão Gênica
Glucosamina/química
Proteínas Facilitadoras de Transporte de Glucose/genética
Glicoconjugados/metabolismo
Glicoconjugados/farmacologia
Seres Humanos
Simulação de Dinâmica Molecular
Terapia de Alvo Molecular
Neuroglia/metabolismo
Neuroglia/patologia
Conformação de Ácido Nucleico
Pirróis/química
Estreptozocina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Antineoplastic Agents, Alkylating); 0 (DNA Adducts); 0 (DNA, Neoplasm); 0 (Glucose Transport Proteins, Facilitative); 0 (Glycoconjugates); 0 (N3-methyladenine); 0 (Pyrroles); 5W494URQ81 (Streptozocin); JAC85A2161 (Adenine); N08U5BOQ1K (Glucosamine)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170515
[Lr] Data última revisão:
170515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161222
[St] Status:MEDLINE
[do] DOI:10.1021/acs.biochem.6b01075


  9 / 989 MEDLINE  
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[PMID]:27816868
[Au] Autor:Liley JR; Penfold J; Thomas RK; Tucker IM; Petkov JT; Stevenson PS; Banat IM; Marchant R; Rudden M; Terry A; Grillo I
[Ad] Endereço:Physical and Theoretical Chemistry Laboratory, Oxford University, South Parks Road, Oxford, UK.
[Ti] Título:Self-assembly in dilute mixtures of non-ionic and anionic surfactants and rhamnolipd biosurfactants.
[So] Source:J Colloid Interface Sci;487:493-503, 2017 Feb 01.
[Is] ISSN:1095-7103
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The self-assembly of dilute aqueous solutions of a ternary surfactant mixture and rhamnolipid biosurfactant/surfactant mixtures has been studied by small angle neutron scattering. In the ternary surfactant mixture of octaethylene glycol monododecyl ether, C E , sodium dodecyl 6-benzene sulfonate, LAS, and sodium dioxyethylene monododecyl sulfate, SLES, small globular interacting micelles are observed over the entire composition and concentration range studied. The modelling of the scattering data strongly supports the assumption that the micelle compositions are close to the solution compositions. In the 5-component rhamnolipid/surfactant mixture of the mono-rhamnose, R1, di-rhamnose, R2, rhamnolipids with C E /LAS/SLES, globular micelles are observed over much of the concentration and composition range studied. However, for solutions relatively rich in rhamnolipid and LAS, lamellar/micellar coexistence is observed. The transition from globular to more planar structures arises from a synergistic packing in the 5 component mixture. It is not observed in the individual components nor in the ternary C E /LAS/SLES mixture at these relatively low concentrations. The results provide an insight into how synergistic packing effects can occur in the solution self-assembly of complex multi-component surfactant mixtures, and give rise to an unexpected evolution in the phase behaviour.
[Mh] Termos MeSH primário: Alcanossulfonatos/química
Glicolipídeos/química
Tensoativos/química
Água/química
[Mh] Termos MeSH secundário: Benzenossulfonatos/química
Micelas
Difração de Nêutrons
Polietilenoglicóis/química
Ramnose/química
Espalhamento a Baixo Ângulo
Dodecilsulfato de Sódio/análogos & derivados
Dodecilsulfato de Sódio/química
Soluções
Tensão Superficial
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Benzenesulfonates); 0 (Glycolipids); 0 (Micelles); 0 (Solutions); 0 (Surface-Active Agents); 0 (rhamnolipid); 059QF0KO0R (Water); 3055-98-9 (dodecyloctaethyleneglycol monoether); 30IQX730WE (Polyethylene Glycols); 368GB5141J (Sodium Dodecyl Sulfate); 60NSK897G9 (dodecylbenzenesulfonic acid); BPV390UAP0 (sodium laureth sulfate); QN34XC755A (Rhamnose)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170917
[Lr] Data última revisão:
170917
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE


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[PMID]:27692882
[Au] Autor:Kwon HO; Kim HY; Park YM; Seok KS; Oh JE; Choi SD
[Ad] Endereço:School of Urban and Environmental Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
[Ti] Título:Updated national emission of perfluoroalkyl substances (PFASs) from wastewater treatment plants in South Korea.
[So] Source:Environ Pollut;220(Pt A):298-306, 2017 Jan.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A nationwide emission estimate of perfluoroalkyl substances (PFASs) from wastewater treatment plants (WWTPs) is required to understand the source-receptor relationship of PFASs and to manage major types of WWTPs. In this study, the concentrations of 13 PFASs (8 perfluorocarboxylic acids, 3 perfluoroalkane sulfonates, and 2 intermediates) in wastewater and sludge from 81 WWTPs in South Korea were collected. The emission pathways of PFASs were redefined, and then the national emission of PFASs from WWTPs was rigorously updated. In addition to the direct calculations, Monte Carlo simulations were also used to calculate the likely range of PFAS emissions. The total (Σ PFAS) emission (wastewater + sludge) calculated from the direct calculation with mean concentrations was 4.03 ton/y. The emissions of perfluorooctanoic acid (PFOA, 1.19 ton/y) and perfluorooctane sulfonate (PFOS, 1.01 ton/y) were dominant. The Monte Carlo simulations suggested that the realistic national emission of Σ PFASs is between 2 ton/y and 20 ton/y. Combined WWTPs treating municipal wastewater from residential and commercial areas were identified as a major emission source, contributing 65% to the total PFAS emissions. The Han and Nakdong Rivers were the primary contaminated rivers, receiving 89% of the total PFAS discharge from WWTPs. The results and methodologies in this study can be useful to establish a management policy for PFASs.
[Mh] Termos MeSH primário: Fluorcarbonetos/análise
Águas Residuais/química
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Alcanossulfonatos/análise
Ácidos Alcanossulfônicos/análise
Caprilatos/análise
Monitoramento Ambiental
Fluorcarbonetos/química
República da Coreia
Rios
Esgotos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanesulfonates); 0 (Alkanesulfonic Acids); 0 (Caprylates); 0 (Fluorocarbons); 0 (Sewage); 0 (Waste Water); 0 (Water Pollutants, Chemical); 947VD76D3L (perfluorooctanoic acid); 9H2MAI21CL (perfluorooctane sulfonic acid)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE



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