Base de dados : MEDLINE
Pesquisa : D02.455.326.146.432 [Categoria DeCS]
Referências encontradas : 1803 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 181 ir para página                         

  1 / 1803 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29291460
[Au] Autor:Choi JH; Lee S; Nah JY; Kim HK; Paek JS; Lee S; Ham H; Hong SK; Yun SH; Lee T
[Ad] Endereço:Microbial Safety Team, National Institute of Agricultural Science, Rural Development Administration, Wanju 55365, Republic of Korea.
[Ti] Título:Species composition of and fumonisin production by the Fusarium fujikuroi species complex isolated from Korean cereals.
[So] Source:Int J Food Microbiol;267:62-69, 2018 Feb 21.
[Is] ISSN:1879-3460
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:To assess the risk of fumonisin contamination in Korean cereals, we isolated colonies of the Fusarium fujikuroi species complex (FFSC) from barley, maize, rice and soybean samples from 2011 to 2015. A total of 878 FFSC strains were isolated mostly from maize and rice, and species identity of the isolates were determined using the DNA sequence of the translation elongation factor 1-α (TEF-1α) and RNA polymerase II (RPB2) genes. Fusaria recovered from Korean cereals included F. fujikuroi (317 isolates and a frequency of 36%), F. proliferatum (212 isolates and 24.1%), F. verticillioides (170 isolates and 19.4%), F. concentricum (86 strains and 9.8%), F. andiyazi (56 isolates and 6.4%), F. subglutinans (28 isolates and 3.2%), F. thapsinum (5 isolates and 0.6%), and F. circinatum (2 isolates and 0.2%). The rice samples were dominated by F. fujikuroi (47.4%), F. proliferatum (27.3%), and F. concentricum (15.1%), whereas maize samples were dominated by F. verticillioides (33.9%), F. fujikuroi (25.3%), and F. proliferatum (21.1%). A phylogenetic analysis of 70 representative isolates demonstrated that each species was resolved as genealogically exclusive in the ML tree. Fumonisin production potential was evaluated using a PCR assay for the fumonisin biosynthesis gene, FUM1 in all of the isolates. Most of the isolates tested (94%) were positive for FUM1. All of the isolates assigned to F. fujikuroi, F. proliferatum, F. verticillioides and F. thapsinum were positive for FUM1 irrespective of their host origin. Seventy-seven representative isolates positive for FUM1 were examined for fumonisin production in rice medium. The majority of F. proliferatum (26/27, 96.3%), F. verticillioides (16/17, 94.1%) and F. fujikuroi (19/25, 76.0%) produced both FB and FB . Notably, 16 of 19 fumonisin-producing F. fujikuroi produced >1000µg/g of fumonisins (FB +FB ) in rice medium, which is higher than that in previous reports. These results suggest that F. fujikuroi can produce high levels of fumonisins similar to F. verticillioides and F. proliferatum.
[Mh] Termos MeSH primário: Grãos Comestíveis/química
Grãos Comestíveis/microbiologia
Fumonisinas/química
Fusarium/isolamento & purificação
[Mh] Termos MeSH secundário: Biodiversidade
Fumonisinas/análise
Fumonisinas/metabolismo
Fusarium/classificação
Fusarium/genética
Fator 1 de Elongação de Peptídeos/genética
Filogenia
RNA Polimerase II/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins); 0 (Peptide Elongation Factor 1); EC 2.7.7.- (RNA Polymerase II)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180102
[St] Status:MEDLINE


  2 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28830150
[Au] Autor:Kamala A; Kimanya M; Lachat C; Jacxsens L; Haesaert G; Kolsteren P; Ortiz J; Tiisekwa B; De Meulenaer B
[Ad] Endereço:nutriFOODchem unit, Department of Food Safety and Food Quality, partner in Food2Know, Faculty of Bioscience Engineering, Ghent University , Coupure Links 653, 9000 Ghent, Belgium.
[Ti] Título:Risk of Exposure to Multiple Mycotoxins from Maize-Based Complementary Foods in Tanzania.
[So] Source:J Agric Food Chem;65(33):7106-7114, 2017 Aug 23.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study estimated exposure to multiple mycotoxins in 249 infants aged between 6 and 12 months in three agro-ecological zones of Tanzania. Maize-based complementary food intakes were estimated using two 24 h dietary recalls. Using @Risk software, probabilistic exposure assessment was conducted by modeling maize intake data (kg/kg body weight/day) with previously determined multiple mycotoxin (except for ochratoxin A (OTA) and zearalenone (ZEA), present in only a few samples) contamination data (µg/kg) in maize. Maize intakes ranged from 0.13 to 185 g/child/day (average = 59 ± 36 g/child/day). The estimated mean exposures were higher for aflatoxins (6-fold), fumonisins (3-fold), and deoxynivalenol (2-fold) than health-based guidance values of 0.017 ng/kg body weight/day, 2 µg/kg body weight/day, and 1 µg/kg body weight/day, respectively. The population at risk of exposures above the limits of health concern ranged from 12% for HT-2 toxin through 35% for deoxynivalenol to 100% for aflatoxins. The exposure varied among the agro-ecological zones. Strategies targeting multiple mycotoxins in maize are urgently needed to minimize exposures in Tanzania.
[Mh] Termos MeSH primário: Contaminação de Alimentos/análise
Micotoxinas/análise
Zea mays/química
[Mh] Termos MeSH secundário: Fumonisinas/análise
Fumonisinas/metabolismo
Fungos/metabolismo
Seres Humanos
Micotoxinas/metabolismo
Ocratoxinas/análise
Ocratoxinas/metabolismo
Tanzânia
Tricotecenos/análise
Tricotecenos/metabolismo
Zea mays/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins); 0 (Mycotoxins); 0 (Ochratoxins); 0 (Trichothecenes); 1779SX6LUY (ochratoxin A); JT37HYP23V (deoxynivalenol)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170914
[Lr] Data última revisão:
170914
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.6b03429


  3 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28719747
[Au] Autor:Tonti S; Mandrioli M; Nipoti P; Pisi A; Toschi TG; Prodi A
[Ad] Endereço:Department of Agricultural Sciences (DipSA) and §Department of Agricultural and Food Sciences (DiSTAL), University of Bologna , Viale Giuseppe Fanin 40, 40127 Bologna, Italy.
[Ti] Título:Detection of Fumonisins in Fresh and Dehydrated Commercial Garlic.
[So] Source:J Agric Food Chem;65(32):7000-7005, 2017 Aug 16.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:An epidemic fungal disease caused by Fusarium proliferatum, responsible for fumonisin production (FB1, FB2, and FB3), has been reported in the main garlic-producing countries in recent years. Fumonisins are a group of structurally related toxic metabolites produced by this pathogen. The aim of this work was to establish an enzyme-linked immunosorbent assay (ELISA) procedure, mostly applied to cereals, that is suitable for fumonisin detection in garlic and compare these results to those obtained by high-performance liquid chromatography (HPLC) and screening of fresh and dehydrated garlic for toxicological risk. The results show good correlation between the two analytical methods. In fresh symptomatic garlic, fumonisin levels were higher in the basal plates than those in the portions with necrotic spots. Among the 56 commercially dehydrated garlic samples screened, three were positive by ELISA test and only one was above the limit of quantitation. The same samples analyzed by HPLC showed the presence of FB1 in trace amounts that was below the limit of quantitation; FB2 and FB3 were absent. The results are reassuring, because no substantial contamination by fumonisins was found in commercial garlic.
[Mh] Termos MeSH primário: Contaminação de Alimentos/análise
Fumonisinas/análise
Alho/química
Micotoxinas/análise
[Mh] Termos MeSH secundário: Contaminação de Alimentos/economia
Manipulação de Alimentos
Fumonisinas/metabolismo
Fusarium/metabolismo
Alho/microbiologia
Micotoxinas/metabolismo
Doenças das Plantas/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins); 0 (Mycotoxins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b02758


  4 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28712299
[Au] Autor:Yuan CW; Huang JT; Chen CC; Tang PC; Huang JW; Lin JJ; Huang SY; Chen SE
[Ti] Título:Evaluation of Efficacy and Toxicity of Exfoliated Silicate Nanoclays as a Feed Additive for Fumonisin Detoxification.
[So] Source:J Agric Food Chem;65(31):6564-6571, 2017 Aug 09.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The efficacy of nanosilicate clay platelets (NSCP), exfoliated silicates from natural montmorillonites, as a feed additive for ameliorating fumonisin B1 (FB1) toxicosis was evaluated. Toxicological mechanisms by NSCP were examined through proteomic and biochemical analyses. Dietary supplementation with NSCP at a low level of 40 mg/kg of feed improved growth performances in chickens with respect to FB1 toxicosis. Other issues of ameliorated symptoms including serum and/or hepatic aspartate aminotransferase activity, oxidative stress indicators, and sphinganine/sphingosine ratio, a hallmark of FB1 toxicosis, were considered. Chickens with NSCP inclusion alone at 1000 mg/kg of feed exhibited no changes in hepatic histology, oxidative status, and serum parameters and even had a higher feed intake. Proteomic analysis with liver tissues identified 45 distinct proteins differentially affected by FB1 and/or NSCP, in which proteins involved in thiol metabolism and redox regulation, glycolysis, carcinogenesis, and detoxification by glutathione S-transferase were promoted by FB1, whereas NSCP caused differential changes of protein abundances related to methionine/cysteine and choline/glycine interconversion for glutathione synthesis, redox regulation by peroxiredoxin, toxin/metabolite delivery by albumin, glycolysis, tricarboxylic acid cycle, adenosine triphosphate (ATP) synthesis, and chaperon escort for endoplasmic reticulum stress relief. Functional analyses confirmed the enhancement of hepatic metabolic processes for ATP and NAD(P)H production to meet the need for detoxification, antioxidative defense, and toxin/metabolite clearance by FB1 or NSCP ingestion. On the basis of the amelioration of FB1 toxicosis, global profile of hepatic protein expressions, and validated toxicological mechanisms, NSCP were concluded as a safe and effective agent for FB1 detoxification.
[Mh] Termos MeSH primário: Silicatos de Alumínio/metabolismo
Ração Animal/análise
Galinhas/metabolismo
Aditivos Alimentares/metabolismo
Fumonisinas/toxicidade
Micotoxinas/toxicidade
Silicatos/metabolismo
[Mh] Termos MeSH secundário: Silicatos de Alumínio/efeitos adversos
Animais
Galinhas/crescimento & desenvolvimento
Fumonisinas/metabolismo
Inativação Metabólica
Fígado/metabolismo
Micotoxinas/metabolismo
Estresse Oxidativo
Silicatos/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Silicates); 0 (Food Additives); 0 (Fumonisins); 0 (Mycotoxins); 0 (Silicates); 1302-87-0 (clay); 3ZZM97XZ32 (fumonisin B1)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170818
[Lr] Data última revisão:
170818
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170718
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b02224


  5 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28636450
[Au] Autor:Robert H; Payros D; Pinton P; Théodorou V; Mercier-Bonin M; Oswald IP
[Ad] Endereço:a Toxalim (Research Centre in Food Toxicology) , Université de Toulouse, INRA, ENVT, INP-Purpan, UPS , Toulouse , France.
[Ti] Título:Impact of mycotoxins on the intestine: are mucus and microbiota new targets?
[So] Source:J Toxicol Environ Health B Crit Rev;20(5):249-275, 2017.
[Is] ISSN:1521-6950
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:There is an increasing awareness of the deleterious effects attributed to mycotoxins during their fate within the gut, particularly for deoxynivalenol (DON), zearalenone (ZEN), ochratoxin A (OTA), fumonisin B1 (FB1), aflatoxin B1 (AFB1), and patulin (PAT). Evidence indicates that disruption of the epithelial barrier is well established. However, intestinal barrier function on its luminal side involves two other partners, mucus and microbiota, which have rarely been considered in the context of mycotoxin exposure. The current review aimed at providing a summary of DON, ZEN, OTA, FB1, AFB1, and PAT effects on intestinal barrier function, with special focus on mucus and microbiota. DON, ZEN, OTA, FB1, AFB1, and PAT are known to markedly affect epithelial cell integrity and functions. Regarding mucus, DON is the most documentated mycotoxin. In vivo, toxicological impact of DON generally has only been assessed through goblet cell number. Evaluation of the mycotoxins/mucus interplay considering other indicators such as composition, thickness, and penetrability of mucus, mucin O-glycosylation thus warrants further attention. With respect to microbiota, few short-term studies to date have been reported indicating deleterious effects. However, long-term exposure to mycotoxins may also produce significant changes in microbiota composition and metabolic activity, which requires further experimentation. In conclusion, mucus and microbiota are key targets for dietary mycotoxins although assessment of induced effects is preliminary. A significant research effort is now underway to determine the adverse consequences of mycotoxins on mucus and microbiota considered as individual but also as tightly connected gut players.
[Mh] Termos MeSH primário: Microbioma Gastrointestinal/efeitos dos fármacos
Mucosa Intestinal/efeitos dos fármacos
Intestinos/efeitos dos fármacos
Micotoxinas/efeitos adversos
[Mh] Termos MeSH secundário: Aflatoxina B1/efeitos adversos
Animais
Fumonisinas/efeitos adversos
Seres Humanos
Mucosa Intestinal/microbiologia
Intestinos/microbiologia
Ocratoxinas/efeitos adversos
Patulina/efeitos adversos
Tricotecenos/efeitos adversos
Zearalenona/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Fumonisins); 0 (Mycotoxins); 0 (Ochratoxins); 0 (Trichothecenes); 1779SX6LUY (ochratoxin A); 3ZZM97XZ32 (fumonisin B1); 5W827M159J (Zearalenone); 95X2BV4W8R (Patulin); 9N2N2Y55MH (Aflatoxin B1); JT37HYP23V (deoxynivalenol)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170920
[Lr] Data última revisão:
170920
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170622
[St] Status:MEDLINE
[do] DOI:10.1080/10937404.2017.1326071


  6 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28551222
[Au] Autor:Smith LL; Francis KA; Johnson JT; Gaskill CL
[Ad] Endereço:University of Kentucky Veterinary Diagnostic Laboratory, Department of Veterinary Science, University of Kentucky, 1490 Bull Lea Road, Lexington, KY 40511, USA. Electronic address: lori.smith@uky.edu.
[Ti] Título:Quantitation of fumonisin B and B in feed using FMOC pre-column derivatization with HPLC and fluorescence detection.
[So] Source:Food Chem;234:174-179, 2017 Nov 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Pre-column derivatization with 9-fluorenylmethyl chloroformate (FMOC-Cl) was determined to be effective for quantitation of fumonisins B and B in feed. Liquid-solid extraction, clean-up using immunoaffinity solid phase extraction chromatography, and FMOC-derivatization preceded analysis by reverse phase HPLC with fluorescence. Instrument response was unchanged in the presence of matrix, indicating no need to use matrix-matched calibrants. Furthermore, high method recoveries indicated calibrants do not need to undergo clean-up to account for analyte loss. Established method features include linear instrument response from 0.04-2.5µg/mL and stable derivatized calibrants over 7days. Fortified cornmeal method recoveries from 0.1-30.0µg/g were determined for FB (75.1%-109%) and FB (96.0%-115.2%). Inter-assay precision ranged from 1.0%-16.7%. Method accuracy was further confirmed using certified reference material. Inter-laboratory comparison with naturally-contaminated field corn demonstrated equivalent results with conventional derivatization. These results indicate FMOC derivatization is a suitable alternative for fumonisins B and B quantitation in corn-based feeds.
[Mh] Termos MeSH primário: Ração Animal/análise
Cromatografia Líquida de Alta Pressão
Contaminação de Alimentos/análise
Fumonisinas/análise
[Mh] Termos MeSH secundário: Cromatografia de Afinidade
Fluorescência
Zea mays
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170529
[St] Status:MEDLINE


  7 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28530554
[Au] Autor:de Oliveira GB; de Castro Gomes Vieira CM; Orlando RM; Faria AF
[Ad] Endereço:Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Brazil.
[Ti] Título:Simultaneous determination of fumonisins B1 and B2 in different types of maize by matrix solid phase dispersion and HPLC-MS/MS.
[So] Source:Food Chem;233:11-19, 2017 Oct 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This work involved the optimization and validation of a method, according to Directive 2002/657/EC and the Analytical Quality Assurance Manual of Ministério da Agricultura, Pecuária e Abastecimento, Brazil, for simultaneous extraction and determination of fumonisins B1 and B2 in maize. The extraction procedure was based on a matrix solid phase dispersion approach, the optimization of which employed a sequence of different factorial designs. A liquid chromatography-tandem mass spectrometry method was developed for determining these analytes using the selected reaction monitoring mode. The optimized method employed only 1g of silica gel for dispersion and elution with 70% ammonium formate aqueous buffer (50mmolL , pH 9), representing a simple, cheap and chemically friendly sample preparation method. Trueness (recoveries: 86-106%), precision (RSD ≤19%), decision limits, detection capabilities and measurement uncertainties were calculated for the validated method. The method scope was expanded to popcorn kernels, white maize kernels and yellow maize grits.
[Mh] Termos MeSH primário: Zea mays
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão
Fumonisinas
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE


  8 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28447535
[Au] Autor:Silva BA; Rosa R; Silva JR; Savi GD; Scussel VM
[Ad] Endereço:a Laboratory of Mycotoxicology and Food Contaminants, Food Science and Technology Department, Center of Agricultural Sciences , Federal University of Santa Catarina , Florianopolis , Brazil.
[Ti] Título:Natural occurrence of fumonisins and characteristics of pamonhas sweet type from Southern Brazil.
[So] Source:Food Addit Contam Part B Surveill;10(3):222-227, 2017 Sep.
[Is] ISSN:1939-3229
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Fresh and frozen pamonhas, a native Brazilian food made with sweet corn (Zea mays L.), similar to the Mexican tamal, which has been incorporated into the country's diet, were investigated for fumonisins (FBs: FB and FB ) contamination and product characteristics. The laboratory conditions of the applied fumonisins method with liquid chromatography and fluorescence detection were validated. Five out of the total samples showed FBs contamination above the national maximum level of 1000-1500 µg/kg. Despite this, in 59.6% (31) of the samples FB and in 23.1% (12) FB could be detected. The pamonhas characteristics did not show uniformity among the brands surveyed. The moisture content of 59.4% and water activity of 0.97 for both (fresh and frozen) samples showed to be suitable conditions for fungal growth. One sample had a quite high pH. It is essential to establish guidance criteria for pamonha production by the regulatory agencies.
[Mh] Termos MeSH primário: Culinária
Contaminação de Alimentos
Fumonisinas/química
Zea mays/química
[Mh] Termos MeSH secundário: Brasil
Seres Humanos
Zea mays/microbiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170829
[Lr] Data última revisão:
170829
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE
[do] DOI:10.1080/19393210.2017.1323802


  9 / 1803 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28303405
[Au] Autor:Yanagawa D; Ishikawa T; Imai H
[Ad] Endereço:Department of Biology, Graduate School of Natural Science, Konan University, Kobe, 658-8501, Japan.
[Ti] Título:Synthesis and degradation of long-chain base phosphates affect fumonisin B -induced cell death in Arabidopsis thaliana.
[So] Source:J Plant Res;130(3):571-585, 2017 May.
[Is] ISSN:1618-0860
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Fumonisin B (FB ), an inducer of cell death, disrupts sphingolipid metabolism; large accumulations of de novo synthesized free long-chain bases (LCBs) are observed. However, it remains unclear whether tolerance to FB toxicity in plants is connected with preventing the accumulation of free LCBs through their phosphorylation. Here a workflow for the extraction, detection and quantification of LCB phosphates (LCBPs) in Arabidopsis thaliana was developed. We studied the effect of expression of genes for three enzymes involved in the synthesis and degradation of LCBPs, LCB kinase (LCBK1), LCBP phosphatase (SPP1) and lyase (DPL1) on FB -induced cell death. As expected, large accumulations of saturated free LCBs, dihydrosphingosine and phytosphingosine, were observed in the FB -treated leaves. On the other hand, a high level of sphingenine phosphate was found in the FB -treated leaves even though free sphingenine was found in low amounts in these leaves. In comparison of WT and spp1 plants, the LCBP/LCB ratio is likely to be correlated with the degree of FB -induced cell death determined by trypan blue staining. The FB -treated leaves in dpl1 plants showed severe cell death and the elevation of free LCBs and LCBPs. LCBK1-OX and -KD plants showed resistance and sensitivity to FB , respectively, whereas free LCB and LCBP levels in FB -treated LCBK1-OX and -KD plants were moderately different to those in FB -treated WT plants. Overall, the findings described here suggest that LCBP/LCB homeostasis is an important topic that participates in the tolerance of plant cells to FB .
[Mh] Termos MeSH primário: Arabidopsis/metabolismo
Morte Celular/efeitos dos fármacos
Fumonisinas/farmacologia
Fosfatos/química
Fosfatos/metabolismo
[Mh] Termos MeSH secundário: Arabidopsis/enzimologia
Proteínas de Arabidopsis/metabolismo
Sequência de Bases
DNA de Plantas
Tolerância a Medicamentos
Regulação da Expressão Gênica de Plantas
Genes de Plantas/genética
Metabolismo/fisiologia
Modelos Biológicos
Monoéster Fosfórico Hidrolases/metabolismo
Fosforilação
Folhas de Planta/química
Folhas de Planta/citologia
Folhas de Planta/efeitos dos fármacos
Folhas de Planta/metabolismo
Esfingolipídeos/metabolismo
Esfingosina/análogos & derivados
Esfingosina/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Arabidopsis Proteins); 0 (DNA, Plant); 0 (Fumonisins); 0 (Phosphates); 0 (Sphingolipids); 3ZZM97XZ32 (fumonisin B1); EC 3.1.3.2 (Phosphoric Monoester Hydrolases); GIN46U9Q2Q (phytosphingosine); NGZ37HRE42 (Sphingosine); OWA98U788S (safingol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE
[do] DOI:10.1007/s10265-017-0923-7


  10 / 1803 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Corrêa, Benedito
Texto completo
[PMID]:28265970
[Au] Autor:Barroso VM; Rocha LO; Reis TA; Reis GM; Duarte AP; Michelotto MD; Correa B
[Ad] Endereço:Microbiology Department, Institute of Biomedical Sciences, University of Sao Paulo, Avenue Prof. Lineu Prestes, 1374, Laboratory 249, Sao Paulo, SP, 05508-000, Brazil.
[Ti] Título:Fusarium verticillioides and fumonisin contamination in Bt and non-Bt maize cultivated in Brazil.
[So] Source:Mycotoxin Res;33(2):121-127, 2017 May.
[Is] ISSN:1867-1632
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Fusarium verticillioides is one of the main pathogens of maize, causing ear and stalk rots. This fungus is also able to produce high levels of fumonisins, which have been linked to various illnesses in humans and animals. Previous studies have shown that maize hybrids genetically modified with the cry genes from the bacterium Bacillus thuringiensis (Bt) presented lower incidence of F. verticillioides and fumonisin levels, presumably through the reduction of insects, which could act as vectors of fungi. The aim of this study was to assess the incidence of F. verticillioides and the concentration of fumonisins in Bt and isogenic non-Bt hybrids (2B710Hx, 30F35YG, 2B710, and 30F35, respectively). The samples of 2B710Hx and 30F35YG presented lower F. verticillioides frequency than 2B710 and 30F35 samples. However, there was no statistical difference between fumonisin contamination when Bt and non-Bt samples were compared (P > 0.05). The results suggest that other environmental parameters could possibly trigger fumonisin production during plant development in the field; consequently, other management strategies should be applied to aid controlling fumonisin contamination in maize.
[Mh] Termos MeSH primário: Fumonisinas/análise
Fusarium/isolamento & purificação
Micotoxinas/análise
Zea mays/química
Zea mays/microbiologia
[Mh] Termos MeSH secundário: Brasil
Plantas Geneticamente Modificadas/química
Plantas Geneticamente Modificadas/microbiologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fumonisins); 0 (Mycotoxins)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170308
[St] Status:MEDLINE
[do] DOI:10.1007/s12550-017-0271-4



página 1 de 181 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde