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Pesquisa : D02.455.326.146.800 [Categoria DeCS]
Referências encontradas : 1740 [refinar]
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  1 / 1740 MEDLINE  
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[PMID]:28641463
[Au] Autor:Du SZ; Kuang F; Liu Y; Chen YG; Zhan R
[Ad] Endereço:a School of Chemistry and Chemical Engineering , Yunnan Normal University , Kunming , China.
[Ti] Título:A new dimeric diarylpropane from Horsfieldia tetratepala.
[So] Source:Nat Prod Res;32(2):162-166, 2018 Jan.
[Is] ISSN:1478-6427
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Five compounds, including a new dimeric diarylpropane, were isolated from the petroleum ether extract of the twigs and leaves of Horsfieldia tetratepala. The structures of these compounds were elucidated by spectroscopic analysis. Moreover, the antiproliferative activities of these compounds were tested on cancer cell lines, but none is active.
[Mh] Termos MeSH primário: Myristicaceae/química
Extratos Vegetais/química
Folhas de Planta/química
[Mh] Termos MeSH secundário: Antineoplásicos/isolamento & purificação
Antineoplásicos/farmacologia
Linhagem Celular Tumoral
Dimerização
Seres Humanos
Estrutura Molecular
Propano
Análise Espectral
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 0 (Plant Extracts); T75W9911L6 (Propane)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170624
[St] Status:MEDLINE
[do] DOI:10.1080/14786419.2017.1342087


  2 / 1740 MEDLINE  
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[PMID]:28745634
[Au] Autor:Ma Z; Wu Z; Miller JT
[Ad] Endereço:Davidson School of Chemical Engineering, Purdue University.
[Ti] Título:Synthesis and Testing of Supported Pt-Cu Solid Solution Nanoparticle Catalysts for Propane Dehydrogenation.
[So] Source:J Vis Exp;(125), 2017 Jul 18.
[Is] ISSN:1940-087X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A convenient method for the synthesis of bimetallic Pt-Cu catalysts and performance tests for propane dehydrogenation and characterization are demonstrated here. The catalyst forms a substitutional solid solution structure, with a small and uniform particle size around 2 nm. This is realized by careful control over the impregnation, calcination, and reduction steps during catalyst preparation and is identified by advanced in situ synchrotron techniques. The catalyst propane dehydrogenation performance continuously improves with increasing Cu:Pt atomic ratio.
[Mh] Termos MeSH primário: Cobre/química
Nanopartículas Metálicas/química
Platina/química
Propano/química
[Mh] Termos MeSH secundário: Catálise
Hidrogênio/química
Tamanho da Partícula
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
49DFR088MY (Platinum); 789U1901C5 (Copper); 7YNJ3PO35Z (Hydrogen); T75W9911L6 (Propane)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180130
[Lr] Data última revisão:
180130
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.3791/56040


  3 / 1740 MEDLINE  
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[PMID]:28799209
[Au] Autor:Yang L; Dolan EM; Tan SK; Lin T; Sontag ED; Khare SD
[Ad] Endereço:Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.
[Ti] Título:Computation-Guided Design of a Stimulus-Responsive Multienzyme Supramolecular Assembly.
[So] Source:Chembiochem;18(20):2000-2006, 2017 Oct 18.
[Is] ISSN:1439-7633
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The construction of stimulus-responsive supramolecular complexes of metabolic pathway enzymes, inspired by natural multienzyme assemblies (metabolons), provides an attractive avenue for efficient and spatiotemporally controllable one-pot biotransformations. We have constructed a phosphorylation- and optically responsive metabolon for the biodegradation of the environmental pollutant 1,2,3-trichloropropane.
[Mh] Termos MeSH primário: Projeto Auxiliado por Computador
Complexos Multienzimáticos/química
[Mh] Termos MeSH secundário: Modelos Moleculares
Propano/análogos & derivados
Propano/química
Domínios Proteicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Multienzyme Complexes); 3MJ7QCK0Z0 (1,2,3-trichloropropane); T75W9911L6 (Propane)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170812
[St] Status:MEDLINE
[do] DOI:10.1002/cbic.201700425


  4 / 1740 MEDLINE  
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[PMID]:28760934
[Au] Autor:Spinler JK; Auchtung J; Brown A; Boonma P; Oezguen N; Ross CL; Luna RA; Runge J; Versalovic J; Peniche A; Dann SM; Britton RA; Haag A; Savidge TC
[Ad] Endereço:Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, USA spinler@bcm.edu.
[Ti] Título:Next-Generation Probiotics Targeting Clostridium difficile through Precursor-Directed Antimicrobial Biosynthesis.
[So] Source:Infect Immun;85(10), 2017 Oct.
[Is] ISSN:1098-5522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Integration of antibiotic and probiotic therapy has the potential to lessen the public health burden of antimicrobial-associated diseases. infection (CDI) represents an important example where the rational design of next-generation probiotics is being actively pursued to prevent disease recurrence. Because intrinsic resistance to clinically relevant antibiotics used to treat CDI (vancomycin, metronidazole, and fidaxomicin) is a desired trait in such probiotic species, we screened several bacteria and identified to be a promising candidate for adjunct therapy. Human-derived bacteria convert glycerol to the broad-spectrum antimicrobial compound reuterin. When supplemented with glycerol, strains carrying the gene locus were potent reuterin producers, with 17938 inhibiting growth at a level on par with the level of growth inhibition by vancomycin. Targeted mutations and complementation studies identified reuterin to be the precursor-induced antimicrobial agent. Pathophysiological relevance was demonstrated when the codelivery of with glycerol was effective against colonization in complex human fecal microbial communities, whereas treatment with either glycerol or alone was ineffective. A global unbiased microbiome and metabolomics analysis independently confirmed that glycerol precursor delivery with elicited changes in the composition and function of the human microbial community that preferentially targets outgrowth and toxicity, a finding consistent with glycerol fermentation and reuterin production. Antimicrobial resistance has thus been successfully exploited in the natural design of human microbiome evasion of , and this method may provide a prototypic precursor-directed probiotic approach. Antibiotic resistance and substrate bioavailability may therefore represent critical new determinants of probiotic efficacy in clinical trials.
[Mh] Termos MeSH primário: Antibacterianos/biossíntese
Infecções por Clostridium/prevenção & controle
Clostridium difficile/crescimento & desenvolvimento
Gliceraldeído/análogos & derivados
Glicerol/administração & dosagem
Lactobacillus reuteri/metabolismo
Probióticos
Propano/metabolismo
[Mh] Termos MeSH secundário: Antibacterianos/farmacologia
Antibacterianos/uso terapêutico
Proteínas de Bactérias/genética
Infecções por Clostridium/imunologia
Infecções por Clostridium/terapia
Clostridium difficile/efeitos dos fármacos
Descoberta de Drogas/métodos
Farmacorresistência Bacteriana
Fezes/microbiologia
Fermentação
Microbioma Gastrointestinal
Gliceraldeído/metabolismo
Gliceraldeído/farmacologia
Gliceraldeído/uso terapêutico
Glicerol/imunologia
Glicerol/metabolismo
Seres Humanos
Metabolômica
Propano/farmacologia
Propano/uso terapêutico
Vancomicina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Bacterial Proteins); 2134-29-4 (3-hydroxypropionaldehyde); 367-47-5 (Glyceraldehyde); 6Q205EH1VU (Vancomycin); PDC6A3C0OX (Glycerol); T75W9911L6 (Propane)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE


  5 / 1740 MEDLINE  
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[PMID]:28737916
[Au] Autor:Choi SK; Mun GI; Choi E; Kim SY; Kwon Y; Na Y; Lee YS
[Ad] Endereço:Graduate School of Pharmaceutical Sciences, Ewha Womans University , Seoul 120-750, Korea.
[Ti] Título:The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection.
[So] Source:J Nat Prod;80(8):2379-2383, 2017 Aug 25.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Coniferyl aldehyde (1) is previously reported as a potent inducer of heat shock factor 1 (HSF1). Here, we further examined the active pharmacophore of 1 for activation of HSF1 using the derivatives coniferyl alcohol (2), 4-hydroxy-3-methoxyphenylpropanal (3), and 4-hydroxy-3-methoxyphenylpropanol (4). Both 1 and 2 resulted in increased survival days after a lethal radiation (IR) dose. The decrease in bone marrow (BM) cellularity and Ki67-positive BM cells by IR was also significantly restored by 1 or 2 in mice. These results suggested that the vinyl moiety of 1 and 2 is necessary for inducing HSF1, which may be useful for developing small molecules for cytoprotection of normal cells against damage by cytotoxic drugs and radiation.
[Mh] Termos MeSH primário: Acroleína/análogos & derivados
Células da Medula Óssea/citologia
Proteínas de Ligação a DNA/metabolismo
Propano/análogos & derivados
Propanóis/farmacologia
Fatores de Transcrição/metabolismo
[Mh] Termos MeSH secundário: Acroleína/química
Acroleína/farmacologia
Animais
Células da Medula Óssea/química
Proteínas de Ligação a DNA/química
Fatores de Transcrição de Choque Térmico
Camundongos
Estrutura Molecular
Propano/química
Propano/farmacologia
Propanóis/química
Fatores de Transcrição/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (4-hydroxy-3-methoxyphenylpropanal); 0 (4-hydroxy-3-methoxyphenylpropanol); 0 (DNA-Binding Proteins); 0 (Heat Shock Transcription Factors); 0 (Propanols); 0 (Transcription Factors); 06TPT01AD5 (coniferaldehyde); 7864XYD3JJ (Acrolein); T75W9911L6 (Propane)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170725
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00126


  6 / 1740 MEDLINE  
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[PMID]:28527381
[Au] Autor:Tang X; Zhang R; Li Y; Zhang Q; Wang W
[Ad] Endereço:Environment Research Institute, Shandong University, Jinan 250100, PR China.
[Ti] Título:Enantioselectivity of haloalkane dehalogenase LinB on the degradation of 1,2-dichloropropane: A QM/MM study.
[So] Source:Bioorg Chem;73:16-23, 2017 Aug.
[Is] ISSN:1090-2120
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The hydrolysis dechlorination mechanism of a chiral organochlorinepollutant, 1,2-dichloropropane (DCP), catalyzed by haloalkane dehalogenase LinB has been investigated by using a combined quantum mechanics/molecular mechanics method. LinB was confirmed to be enantioselective towards the catabolism of the racemic mixture. Based on the S 2 nucleophilic substitution mechanism, the dechlorination process was identified as the rate-determining step in LinB-catalyzed degradation of 1,2-dichloropropane, the Boltzmann-weighted average potential barrier of which is 18.8kcal/mol for the (R)-isomer and 24.0kcal/mol for the (S)-isomer. A particular water molecule near (S)-DCP in the reaction system can strongly disturb the dechlorination process, which can account for the enantioselectivity of LinB. Further electrostatic influence analysis indicates that proper mutation of Gly37 may improve the catalytic efficiency of LinB towards DCP.
[Mh] Termos MeSH primário: Hidrolases/metabolismo
Propano/análogos & derivados
Teoria Quântica
[Mh] Termos MeSH secundário: Hidrolases/química
Hidrólise
Estrutura Molecular
Propano/química
Propano/metabolismo
Estereoisomerismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
EC 3.- (Hydrolases); EC 3.8.1.5 (haloalkane dehalogenase); RRZ023OFWL (propylene dichloride); T75W9911L6 (Propane)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170521
[St] Status:MEDLINE


  7 / 1740 MEDLINE  
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[PMID]:28407924
[Au] Autor:Badertscher R; Freiburghaus C; Wechsler D; Irmler S
[Ad] Endereço:Agroscope, Schwarzenburgstrasse 161, CH-3003 Bern, Switzerland. Electronic address: rene.badertscher@agroscope.admin.ch.
[Ti] Título:Validated method for the determination of propane-1,2-diol, butane-2,3-diol, and propane-1,3-diol in cheese and bacterial cultures using phenylboronic esterification and GC-MS.
[So] Source:Food Chem;230:372-377, 2017 Sep 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A simple, fast, sensitive, and robust gas chromatography-mass spectrometry (GC-MS) method for the simultaneous determination of propane-1,2-diol, butane-2,3-diol, and propane-1,3-diol in cheese and bacterial cultures was developed. Target analytes were extracted and transformed into their phenylboronic esters prior to analysis. The method showed good sensitivity, without carryover between the samples. The detection limits for propane-1,2-diol, butane-2,3-diol, and propane-1,3-diol in cheese samples were 0.26, 0.02, and 0.11mgkg , respectively, and for bacterial culture samples were 1.32, 0.09, and 0.54mgkg , respectively. The Horwitz ratio showed good precision for all analytes (<0.45). The calibrated range in cheese for all analytes was very broad, from 0 to 1000mgkg , and in bacterial cultures was from 0 to 5000mgkg with R >0.9991. The results confirm excellent applicability of the proposed method for the determination of the target metabolites in cheese and bacterial culture samples.
[Mh] Termos MeSH primário: Ácidos Borônicos/química
Butanos/química
Queijo/análise
Ésteres/química
Cromatografia Gasosa-Espectrometria de Massas/métodos
Propano/química
[Mh] Termos MeSH secundário: Esterificação
Ésteres/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Boronic Acids); 0 (Butanes); 0 (Esters); 6LV4FOR43R (butane); L12H7B02G5 (benzeneboronic acid); T75W9911L6 (Propane)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170629
[Lr] Data última revisão:
170629
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170415
[St] Status:MEDLINE


  8 / 1740 MEDLINE  
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[PMID]:28323102
[Au] Autor:Zhou Z; Forbes RT; D'Emanuele A
[Ad] Endereço:School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK. Electronic address: ZZhou2@uclan.ac.uk.
[Ti] Título:Preparation of core-crosslinked linear-dendritic copolymer micelles with enhanced stability and their application for drug solubilisation.
[So] Source:Int J Pharm;523(1):260-269, 2017 May 15.
[Is] ISSN:1873-3476
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:In this study we explore the preparation of core-crosslinked micelles of linear-dendritic methoxy-poly(ethylene glycol) (MPEG)-co-poly(ester-sulfide) (PES) polymers to improve the stability of such polymeric micelle systems against premature disintegration and drug release. A series of MPEG-PES copolymers were synthesised via stepwise reactions of acetylation and thiol-ene photoreaction. Surface tension measurement showed that the copolymers with ethenyl surface groups could self-associate in dilute aqueous solutions to form micelles. Crosslinking within the micelle cores in the presence of dithioerythritol (DTT) linker was initiated under UV radiation. The formation of core-crosslinked micelles was confirmed by HPLC in combination with charged aerosol detection (CAD). The copolymers were found to readily hydrolyse under acidic conditions due to the ester-containing dendrons. Drug solubilisation capacities of the micellar solutions were determined using griseofulvin as a poorly water-soluble model drug. The solubility of griseofulvin showed a 10-fold enhancement in 1% w/v micelle solution and increased with the concentration of the copolymers. Drug release studies indicated that a more sustained release of griseofulvin was achieved for the core-crosslinked micelles compared to the non-crosslinked micelles, attributable to greater stability of the crosslinked core structure. The findings of this study present a new pathway towards developing biodegradable polymeric nanocarriers.
[Mh] Termos MeSH primário: Dendrímeros/química
Micelas
Poliésteres/química
Polietilenoglicóis/química
[Mh] Termos MeSH secundário: Reagentes para Ligações Cruzadas/química
Reagentes para Ligações Cruzadas/efeitos da radiação
Dendrímeros/efeitos da radiação
Ditioeritritol/química
Ditioeritritol/efeitos da radiação
Liberação Controlada de Fármacos
Griseofulvina/química
Poliésteres/efeitos da radiação
Polietilenoglicóis/efeitos da radiação
Propano/análogos & derivados
Propano/química
Propano/efeitos da radiação
Solubilidade
Raios Ultravioleta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (2-hydroxy-1-(4-(hydroxyethoxy)phenyl)-2-methyl-1-propanone); 0 (Cross-Linking Reagents); 0 (Dendrimers); 0 (Micelles); 0 (Polyesters); 30IQX730WE (Polyethylene Glycols); 32HRV3E3D5 (Griseofulvin); 6892-68-8 (Dithioerythritol); 9004-74-4 (monomethoxypolyethylene glycol); T75W9911L6 (Propane)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170322
[St] Status:MEDLINE


  9 / 1740 MEDLINE  
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[PMID]:28321038
[Au] Autor:Take M; Takeuchi T; Hirai S; Takanobu K; Matsumoto M; Fukushima S; Kanno J
[Ad] Endereço:Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety.
[Ti] Título:Distribution of 1,2-dichloropropane in blood and other tissues of rats after oral administration.
[So] Source:J Toxicol Sci;42(2):121-128, 2017.
[Is] ISSN:1880-3989
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The present investigation was undertaken to determine the distribution of 1,2-dichloropropane (DCP) in the blood, liver, kidney, lung, and abdominal fat of rats after oral administration. Male rats were orally administered 62 or 125 mg/kg body weight doses of DCP dissolved in corn oil by gavage, and the concentrations in the blood and tissues were measured. The DCP concentration in the abdominal fat was much greater than in the blood and other tissues. Twenty-four-hr after oral administration, DCP could still be detected in the blood and abdominal fat in the 62-mg/kg group, and in the blood, liver, kidney, lung, and abdominal fat in the 125-mg/kg group. Our results are valuable data pertaining to the pharmacokinetics of DCP and to human health risk assessment of oral exposure to DCP.
[Mh] Termos MeSH primário: Poluentes Ambientais/farmacocinética
Propano/análogos & derivados
Solventes/farmacocinética
[Mh] Termos MeSH secundário: Gordura Abdominal/metabolismo
Administração Oral
Animais
Poluentes Ambientais/sangue
Rim/metabolismo
Fígado/metabolismo
Pulmão/metabolismo
Masculino
Propano/sangue
Propano/farmacocinética
Ratos Endogâmicos F344
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Solvents); RRZ023OFWL (propylene dichloride); T75W9911L6 (Propane)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170801
[Lr] Data última revisão:
170801
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170322
[St] Status:MEDLINE
[do] DOI:10.2131/jts.42.121


  10 / 1740 MEDLINE  
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[PMID]:28300663
[Au] Autor:Toyooka T; Yanagiba Y; Suda M; Ibuki Y; Wang RS
[Ad] Endereço:Industrial Toxicology and Health Effects Research Group, National Institute of Occupational Safety and Health, Japan. Electronic address: toyooka@h.jniosh.go.jp.
[Ti] Título:1,2-Dichloropropane generates phosphorylated histone H2AX via cytochrome P450 2E1-mediated metabolism.
[So] Source:Toxicol Lett;272:60-67, 2017 Apr 15.
[Is] ISSN:1879-3169
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:1,2-Dichloropropane (1,2-DCP), a synthetic chlorinated solvent, was recently classified as carcinogenic. Genotoxic events are known as a crucial step in the initiation of cancer. However, studies on the genotoxicity of 1,2-DCP are very limited, particularly studies investigating the mechanism behind DNA damage by 1,2-DCP. In this study, we examined the genotoxicity of 1,2-DCP using phosphorylated histone H2AX (γ-H2AX), a sensitive DNA damage marker. 1,2-DCP showed dose- (1-10mM: 4h) and time-dependent (1-24h: 5mM) γ-H2AX generation in cultured human hepatocytes (WRL-68) and cholangiocytes (MMNK-1). Additionally, γ-H2AX generation was observed in the livers of mice inhalationally exposed to 1,2-DCP at concentrations of 100, 200, and 400 ppm. During an in vitro mechanistic investigation, we found that γ-H2AX generation by 1,2-DCP was clearly attenuated in the presence of disulfiram and 4-methylpyrazole, a specific cytochrome P450 2E1 (CYP2E1) inhibitor. Furthermore, we showed that 1,2-DCP increased the levels of intracellular reactive oxygen species (ROS), with the increase significantly inhibited by CYP2E1 inhibitors. These results suggested that ROS produced via the cytochrome P450 2E1 metabolic process of 1,2-DCP was a major causal factor for γ-H2AX generation by treatment with 1,2-DCP.
[Mh] Termos MeSH primário: Citocromo P-450 CYP2E1/metabolismo
Histonas/biossíntese
Mutagênicos/toxicidade
Propano/análogos & derivados
[Mh] Termos MeSH secundário: Animais
Ciclo Celular/efeitos dos fármacos
Linhagem Celular
Inibidores do Citocromo P-450 CYP2E1/farmacologia
Dano ao DNA
Relação Dose-Resposta a Droga
Hepatócitos/efeitos dos fármacos
Hepatócitos/metabolismo
Seres Humanos
Exposição por Inalação
Fígado/efeitos dos fármacos
Fígado/metabolismo
Masculino
Camundongos Endogâmicos C57BL
Fosforilação
Propano/toxicidade
Espécies Reativas de Oxigênio/metabolismo
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cytochrome P-450 CYP2E1 Inhibitors); 0 (H2AFX protein, human); 0 (H2AFX protein, mouse); 0 (Histones); 0 (Mutagens); 0 (Reactive Oxygen Species); EC 1.14.13.- (Cytochrome P-450 CYP2E1); RRZ023OFWL (propylene dichloride); T75W9911L6 (Propane)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170317
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde