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Referências encontradas : 129 [refinar]
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[PMID]:28657331
[Au] Autor:Li Y; Yue Q; Jayanetti DR; Swenson DC; Bartholomeusz GA; An Z; Gloer JB; Bills GF
[Ad] Endereço:Texas Therapeutic Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston , Houston, Texas 77054, United States.
[Ti] Título:Anti-Cryptococcus Phenalenones and Cyclic Tetrapeptides from Auxarthron pseudauxarthron.
[So] Source:J Nat Prod;80(7):2101-2109, 2017 Jul 28.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Auxarthrones A-E (1-5), five new phenalenones, and two new naturally occurring cyclic tetrapeptides, auxarthrides A (7) and B (8), were obtained from three different solvent extracts of cultures of the coprophilous fungus Auxarthron pseudauxarthron. Auxarthrones C (3) and E (5) possess an unusual 7a,8-dihydrocyclopenta[a]phenalene-7,9-dione ring system that has not been previously observed in natural products. Formation of 1-5 was found to be dependent on the solvent used for culture extraction. The structures of these new compounds were elucidated primarily by analysis of NMR and MS data. Auxarthrone A (1) was obtained as a mixture of chromatographically inseparable racemic diastereomers (1a and 1b) that cocrystallized, enabling confirmation of their structures by X-ray crystallography. The absolute configurations of 7 and 8 were assigned by analysis of their acid hydrolysates using Marfey's method. Compound 1 displayed moderate antifungal activity against Cryptococcus neoformans and Candida albicans, but did not affect human cancer cell lines.
[Mh] Termos MeSH primário: Antifúngicos/isolamento & purificação
Antifúngicos/farmacologia
Ascomicetos/química
Cryptococcus neoformans/efeitos dos fármacos
Peptídeos Cíclicos/isolamento & purificação
Peptídeos Cíclicos/farmacologia
Fenalenos/isolamento & purificação
Fenalenos/farmacologia
[Mh] Termos MeSH secundário: Antifúngicos/química
Neoplasias da Mama/tratamento farmacológico
Candida albicans/efeitos dos fármacos
Cristalografia por Raios X
Feminino
Seres Humanos
Testes de Sensibilidade Microbiana
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Peptídeos Cíclicos/química
Fenalenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Peptides, Cyclic); 0 (Phenalenes); 548-39-0 (phenalen-1-one)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171008
[Lr] Data última revisão:
171008
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.7b00341


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[PMID]:28577908
[Au] Autor:Gombodorj S; Yang MH; Shang ZC; Liu RH; Li TX; Yin GP; Kong LY
[Ad] Endereço:State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, People's Republic of China.
[Ti] Título:New phenalenone derivatives from Pinellia ternata tubers derived Aspergillus sp.
[So] Source:Fitoterapia;120:72-78, 2017 Jul.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Nine new phenalenone derivatives (1-9), along with two known analogues (10-11) have been isolated from the solid cultures of an endophytic fungus Aspergillus sp. which was obtained from Pinellia ternate. Their structures were established through interpretations of spectroscopic evidence, and some of their absolute configurations were determined by electronic circular dichroism (ECD) and Mo (OCOCH ) induced ECD. All of the phenalenones are unusual acyclic diterpenoid adducts, which are diversely oxidized and partly epoxidized to form different heterocycles. In addition, compound 10 exhibited significant antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis with MIC values of 1.87, 2.77, and 4.80µg/mL, respectively.
[Mh] Termos MeSH primário: Antibacterianos/química
Aspergillus/química
Fenalenos/química
Pinellia/microbiologia
Tubérculos/química
[Mh] Termos MeSH secundário: Antibacterianos/isolamento & purificação
Bacillus subtilis/efeitos dos fármacos
Endófitos/química
Fenalenos/isolamento & purificação
Pseudomonas aeruginosa/efeitos dos fármacos
Staphylococcus aureus/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Phenalenes); 548-39-0 (phenalen-1-one)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170605
[St] Status:MEDLINE


  3 / 129 MEDLINE  
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[PMID]:28146104
[Au] Autor:Brkljaca R; Schneider B; Hidalgo W; Otálvaro F; Ospina F; Lee S; Hoshino M; Fujita M; Urban S
[Ad] Endereço:School of Science (Applied Chemistry and Environmental Science), RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia. robert.brkljaca@rmit.edu.au.
[Ti] Título:Application of the Crystalline Sponge Method to Revise the Structure of the Phenalenone Fuliginone.
[So] Source:Molecules;22(2), 2017 Jan 30.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The structure of fuliginone was revised from a phenyl substituted phenalenone to a hydroxyl substituted phenalenone as a result of its re-purification via HPLC with subsequent NMR analysis together with an independent synthesis and analysis of the crystal structure, which was secured via the crystalline sponge method. On-flow High Performance Liquid Chromatography coupled to Nuclear Magnetic Resonance spectroscopy (HPLC-NMR) was employed to confirm the presence of the natural product in the plant extract and to monitor for any possible degradation or conversion of the compound.
[Mh] Termos MeSH primário: Fenalenos/química
Fenalenos/isolamento & purificação
[Mh] Termos MeSH secundário: Produtos Biológicos/química
Produtos Biológicos/isolamento & purificação
Cromatografia Líquida de Alta Pressão
Cromatografia Gasosa-Espectrometria de Massas
Espectroscopia de Ressonância Magnética
Estrutura Molecular
Extratos Vegetais/química
Extratos Vegetais/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biological Products); 0 (Phenalenes); 0 (Plant Extracts); 548-39-0 (phenalen-1-one)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170509
[Lr] Data última revisão:
170509
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170202
[St] Status:MEDLINE


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[PMID]:27839785
[Au] Autor:Hölscher D; Vollrath A; Kai M; Dhakshinamoorthy S; Menezes RC; Svatos A; Schubert US; Buerkert A; Schneider B
[Ad] Endereço:Research Group Biosynthesis/NMR, Max Planck Institute for Chemical Ecology, Hans-Knöll-Str. 8, 07745 Jena, Germany; Organic Plant Production and Agroecosystems Research in the Tropics and Subtropics (OPATS), University of Kassel, Steinstr. 19, 37213 Witzenhausen, Germany. Electronic address: hoelsch
[Ti] Título:Local phytochemical response of Musa acuminata × balbisiana Colla cv. 'Bluggoe' (ABB) to colonization by Sternorrhyncha.
[So] Source:Phytochemistry;133:26-32, 2017 Jan.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The interaction of two Sternorrhyncha species, the banana aphid (Pentalonia nigronervosa Coquerel (Hemiptera: Aphididae, Aphidinae)), vector of the banana bunchy top virus (BBTV), and the latania scale (Hemiberlesia lataniae Signoret (Hemiptera: Diaspididae, Diaspidinae)) with Musa acuminata × balbisiana Colla (ABB Group) 'Bluggoe' (Musaceae) was investigated by a combination of conventional and spatially resolved analytical techniques, H NMR, UHPLC-MS, and matrix-free UV-laser desorption/ionization MS imaging. After infestation, the feeding sites of P. nigronervosa on the pseudostem and the exocarp of banana fruit developed a red tinge, in which tissue-specific accumulations of phenylphenalenones were discovered. Phenylphenalenones were also detected in the black mats of sooty molds growing on the banana aphid exudates and in the dorsal scales of H. lataniae. This suggests that although these secondary metabolites play a role in the reaction of banana plants towards attack by sucking insects, an aphid and an armored scale have established mechanisms to exude these metabolites before they deploy their deleterious effect.
[Mh] Termos MeSH primário: Afídeos/fisiologia
Musa/química
[Mh] Termos MeSH secundário: Animais
Afídeos/patogenicidade
Babuvirus
Lepidópteros/patogenicidade
Lepidópteros/fisiologia
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Fenalenos/química
Fenalenos/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phenalenes)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170303
[Lr] Data última revisão:
170303
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161115
[St] Status:MEDLINE


  5 / 129 MEDLINE  
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[PMID]:27816177
[Au] Autor:Chen Y; Paetz C; Menezes RC; Schneider B
[Ad] Endereço:Max-Planck Institut für Chemische Ökologie, Beutenberg Campus, Hans-Knöll-Strasse 8, 07745, Jena, Germany; Jiangsu Key Laboratory for Research and Utilization of Plant Resources, Institute of Botany, Jiangsu Province and Chinese Academy of Sciences, Qianhu Houcun 1, 210014, Nanjing, China.
[Ti] Título:Cultured roots of Xiphidium caeruleum: Phenylphenalenones and their biosynthetic and extractant-dependent conversion.
[So] Source:Phytochemistry;133:15-25, 2017 Jan.
[Is] ISSN:1873-3700
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Phytochemical investigation of root cultures of Xiphidium caeruleum (Haemodoraceae) resulted in the structure elucidation of five previously undescribed phenylphenalenone-type compounds, structure revision of a phenylphenalenone glucoside, and identification of nine additional constituents previously reported from other Haemodoraceae and Musaceae plants. The observed extractant-dependent metabolic profiles indicated that phenylphenalenones had been converted hydrolytically and oxidatively. Stable isotope labeling experiments extended the understanding of the phenylphenalenone pathway in plants and provided evidence for a network of biosynthetic and spontaneous conversions linking phenylphenalenones and their derivatives detected in extracts of cultured roots of this plant.
[Mh] Termos MeSH primário: Magnoliopsida/química
Fenalenos/química
Raízes de Plantas/química
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão
Glucosídeos/química
Estrutura Molecular
Fenalenos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucosides); 0 (Phenalenes)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE


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[PMID]:27966935
[Au] Autor:Zang Y; Genta-Jouve G; Escargueil AE; Larsen AK; Guedon L; Nay B; Prado S
[Ad] Endereço:Unité Molécules de Communication et Adaptation des Micro-organismes (UMR 7245), Sorbonne Université, Muséum National d'Histoire Naturelle , CNRS, CP 54, 57 Rue Cuvier, 75005 Paris, France.
[Ti] Título:Antimicrobial Oligophenalenone Dimers from the Soil Fungus Talaromyces stipitatus.
[So] Source:J Nat Prod;79(12):2991-2996, 2016 Dec 23.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:New polyketide-derived oligophenalenone dimers, 9a-epi-bacillisporin E (1) and bacillisporins F-H (2-5), along with the known bacillisporin A (6), were isolated from the fungus Talaromyces stipitatus. Their structures and absolute configurations were determined on the basis of spectroscopic analyses, electronic circular dichroism, and GIAO NMR shift calculation followed by DP4 analysis. The antimicrobial activity of these compounds was evaluated against a panel of human pathogenic bacteria. Among them, bacillisporin H (5) exhibited antimicrobial activity together with modest cytotoxicity against HeLa cells.
[Mh] Termos MeSH primário: Anti-Infecciosos/isolamento & purificação
Anti-Infecciosos/farmacologia
Fenalenos/isolamento & purificação
Fenalenos/farmacologia
Talaromyces/química
[Mh] Termos MeSH secundário: Anti-Infecciosos/química
Bactérias/efeitos dos fármacos
Enterococcus faecalis/efeitos dos fármacos
Escherichia coli/efeitos dos fármacos
Células HeLa
Seres Humanos
Testes de Sensibilidade Microbiana
Estrutura Molecular
Ressonância Magnética Nuclear Biomolecular
Fenalenos/química
Microbiologia do Solo
Staphylococcus aureus/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Phenalenes); 0 (bacillisporin E); 548-39-0 (phenalen-1-one)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170503
[Lr] Data última revisão:
170503
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161215
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.6b00458


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[PMID]:26978228
[Au] Autor:Gao SS; Duan A; Xu W; Yu P; Hang L; Houk KN; Tang Y
[Ad] Endereço:Department of Chemical and Biomolecular Engineering and ‡Department of Chemistry and Biochemistry, University of California , Los Angeles, California 90095, United States.
[Ti] Título:Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase.
[So] Source:J Am Chem Soc;138(12):4249-59, 2016 Mar 30.
[Is] ISSN:1520-5126
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Phenalenones are polyketide natural products that display diverse structures and biological activities. The core of phenalenones is a peri-fused tricyclic ring system cyclized from a linear polyketide precursor via an unresolved mechanism. Toward understanding the unusual cyclization steps, the phn biosynthetic gene cluster responsible for herqueinone biosynthesis was identified from the genome of Penicillium herquei. A nonreducing polyketide synthase (NR-PKS) PhnA was shown to synthesize the heptaketide backbone and cyclize it into the angular, hemiketal-containing naphtho-γ-pyrone prephenalenone. The product template (PT) domain of PhnA catalyzes only the C4-C9 aldol condensation, which is unprecedented among known PT domains. The transformation of prephenalenone to phenalenone requires an FAD-dependent monooxygenase (FMO) PhnB, which catalyzes the C2 aromatic hydroxylation of prephenalenone and ring opening of the γ-pyrone ring simultaneously. Density functional theory calculations provide insights into why the hydroxylated intermediate undergoes an aldol-like phenoxide-ketone cyclization to yield the phenalenone core. This study therefore unveiled new routes and biocatalysts for polyketide cyclization.
[Mh] Termos MeSH primário: Flavinas/metabolismo
Oxigenases/metabolismo
Fenalenos/química
Policetídeo Sintases/metabolismo
[Mh] Termos MeSH secundário: Catálise
Cromatografia Líquida
Ciclização
Fungos/enzimologia
Fungos/genética
Estrutura Molecular
Família Multigênica
Policetídeo Sintases/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Flavins); 0 (Phenalenes); 548-39-0 (phenalen-1-one); 79956-01-7 (Polyketide Synthases); EC 1.13.- (Oxygenases); EC 1.14.13.8 (dimethylaniline monooxygenase (N-oxide forming))
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170403
[Lr] Data última revisão:
170403
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160316
[St] Status:MEDLINE
[do] DOI:10.1021/jacs.6b01528


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[PMID]:26840293
[Au] Autor:Elsebai MF; Ghabbour HA; Mehiri M
[Ad] Endereço:Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. elsebai72@yahoo.com.
[Ti] Título:Unusual Nitrogenous Phenalenone Derivatives from the Marine-Derived Fungus Coniothyrium cereale.
[So] Source:Molecules;21(2):178, 2016 Feb 01.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The new phenalenone metabolites 1, 2, 4, and 6 were isolated from the marine-derived endophytic fungus Coniothyrium cereale, in addition to the ergostane-type sterol (3) and entatrovenetinone (5). Compounds 1 and 2 represent two unusual nitrogen-containing compounds, which are composed of a sterol portion condensed via two bonds to phenalenone derivatives. Compound 6, which contains unprecedented imine functionality between two carbonyl groups to form a oxepane -imine-dione ring, exhibited a moderate cytotoxicity against K562, U266, and SKM1 cancer cell lines. Moreover, molecular docking studies were done on estrogen receptor α-ligand binding domain (ERα-LBD) to compounds 1 and 2 to correlate with binding energies and affinities calculated from molecular docking to the anti-proliferative activity.
[Mh] Termos MeSH primário: Ascomicetos/química
Nitrogênio/química
Fenalenos/síntese química
Fenalenos/farmacologia
[Mh] Termos MeSH secundário: Linhagem Celular Tumoral
Citostáticos/síntese química
Citostáticos/química
Citostáticos/farmacologia
Receptor alfa de Estrogênio/metabolismo
Seres Humanos
Células K562
Modelos Moleculares
Simulação de Acoplamento Molecular
Fenalenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Cytostatic Agents); 0 (Estrogen Receptor alpha); 0 (Phenalenes); 548-39-0 (phenalen-1-one); N762921K75 (Nitrogen)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160204
[St] Status:MEDLINE


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[PMID]:26630185
[Au] Autor:Tabenski I; Cieplik F; Tabenski L; Regensburger J; Hiller KA; Buchalla W; Maisch T; Späth A
[Ad] Endereço:Department of Conservative Dentistry and Periodontology, University Medical Center Regensburg, Regensburg, Germany.
[Ti] Título:The impact of cationic substituents in phenalen-1-one photosensitizers on antimicrobial photodynamic efficacy.
[So] Source:Photochem Photobiol Sci;15(1):57-68, 2016 Jan.
[Is] ISSN:1474-9092
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Light-mediated killing of pathogens by cationic photosensitizers (PS) is a promising antimicrobial approach avoiding resistance as being present upon the use of antibiotics. In this study we focused on the impact of the substituents in phenalen-1-one PS. Photodynamic efficacy depending on positively charged moieties including a primary aliphatic, quaternary aliphatic, aromatic ammonium and a guanidinium cation was investigated against Gram-positive and Gram-negative pathogens. Considering the altered steric demand and lipophilicity of these functional groups we deduced a structure-activity relationship. SAGUA was the most potent PS in this series reaching a maximum efficacy of ≥6log10 steps of bacteria killing at a concentration of 10 µM upon irradiation with blue light (20 mW cm(-2)) for 60 s (1.2 J cm(-2)) without exhibiting inherent dark toxicity. Its guanidinium moiety may be able to form strong bidentate and directional hydrogen bonds to carboxylate groups of bacterial surfaces in addition to ionic charge attraction. This may supplement fast and effective antimicrobial activity.
[Mh] Termos MeSH primário: Antibacterianos/química
Antibacterianos/farmacologia
Fenalenos/química
Fotoquimioterapia
Fármacos Fotossensibilizantes/química
Fármacos Fotossensibilizantes/farmacologia
[Mh] Termos MeSH secundário: Actinomyces/efeitos dos fármacos
Antibacterianos/síntese química
Cátions/química
Relação Dose-Resposta a Droga
Enterococcus faecalis/efeitos dos fármacos
Escherichia coli/efeitos dos fármacos
Testes de Sensibilidade Microbiana
Estrutura Molecular
Fármacos Fotossensibilizantes/síntese química
Staphylococcus aureus/efeitos dos fármacos
Streptococcus mutans/efeitos dos fármacos
Relação Estrutura-Atividade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Cations); 0 (Phenalenes); 0 (Photosensitizing Agents); 548-39-0 (phenalen-1-one)
[Em] Mês de entrada:1609
[Cu] Atualização por classe:160107
[Lr] Data última revisão:
160107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151203
[St] Status:MEDLINE
[do] DOI:10.1039/c5pp00262a


  10 / 129 MEDLINE  
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[PMID]:26290378
[Au] Autor:Hidalgo W; Chandran JN; Menezes RC; Otálvaro F; Schneider B
[Ad] Endereço:Max-Planck Institut für Chemische Ökologie, Beutenberg Campus, Hans-Knöll-Strasse 8, Jena, 07745, Germany.
[Ti] Título:Phenylphenalenones protect banana plants from infection by Mycosphaerella fijiensis and are deactivated by metabolic conversion.
[So] Source:Plant Cell Environ;39(3):492-513, 2016 Mar.
[Is] ISSN:1365-3040
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Phenylphenalenones, polycyclic aromatic natural products from some monocotyledonous plants, are known as phytoalexins in banana (Musa spp.). In this study, (1) H nuclear magnetic resonance (NMR)-based metabolomics along with liquid chromatography and mass spectrometry were used to explore the chemical responses of the susceptible 'Williams' and the resistant 'Khai Thong Ruang' Musa varieties to the ascomycete fungus Mycosphaerella fijiensis, the agent of the black leaf Sigatoka disease. Principal component analysis discriminated strongly between infected and non-infected plant tissue, mainly because of specialized metabolism induced in response to the fungus. Phenylphenalenones are among the major induced compounds, and the resistance level of the plants was correlated with the progress of the disease. However, a virulent strain of M. fijiensis was able to overcome plant resistance by converting phenylphenalenones to sulfate conjugates. Here, we report the first metabolic detoxification of fungitoxic phenylphenalenones to evade the chemical defence of Musa plants.
[Mh] Termos MeSH primário: Ascomicetos/fisiologia
Musa/metabolismo
Musa/microbiologia
Fenalenos/farmacologia
Doenças das Plantas/microbiologia
[Mh] Termos MeSH secundário: Antifúngicos/farmacologia
Ascomicetos/efeitos dos fármacos
Bioensaio
Biomassa
Cromatografia Líquida de Alta Pressão
Interações Hospedeiro-Patógeno/efeitos dos fármacos
Metaboloma/efeitos dos fármacos
Testes de Sensibilidade Microbiana
Musa/efeitos dos fármacos
Fenalenos/química
Análise de Componente Principal
Espectroscopia de Prótons por Ressonância Magnética
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Phenalenes)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150821
[St] Status:MEDLINE
[do] DOI:10.1111/pce.12630



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde