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[PMID]:28986081
[Au] Autor:Garcia-Heras MS; Arroyo B; Simmons RE; Camarero PR; Mateo R; Mougeot F
[Ad] Endereço:FitzPatrick Institute of African Ornithology, DST-NRF Centre of Excellence, University of Cape Town, Private Bag X3, Rondebosch 7701, South Africa. Electronic address: ms.garciaheras@gmail.com.
[Ti] Título:Blood concentrations of PCBs and DDTs in an avian predator endemic to southern Africa: Associations with habitat, electrical transformers and diet.
[So] Source:Environ Pollut;232:440-449, 2018 Jan.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Persistent pollutants such as organochlorine compounds (OCs) have been highlighted as a cause of population decline in avian predators. Understanding patterns of OCs contamination can be crucial for the conservation of affected species, yet little is known on these threats to African raptors. Here we report on OC concentrations in an endangered predator endemic to southern Africa, the Black Harrier Circus maurus. Blood samples were collected in 2012-2014 from wild nestlings (n = 90) and adults (n = 23) in south-western South Africa, where agriculture and urbanization have developed rapidly since the 1950s. Polychlorinated biphenyl (ΣPCB) and dichlorodiphenyltrichloroethane (ΣDDT, for p,p'-DDT + p,p'-DDE) were detected in 79% and 84% of sampled individuals, respectively, with varying concentrations among demographic groups: nestlings had significantly higher ΣPCB and p,p'-DDT concentrations than adults, while adults had higher levels of p,p'-DDE than nestlings. Levels of ΣPCB significantly increased with an index of electric transformer density, a measure of the number and power of electric transformers around active nests. We propose this index as a useful tool for assessing ΣPCB exposure risk in other wildlife. Levels of p,p'-DDE significantly increased with the proportion of wetlands within the breeding territory, and also with the proportion of bird biomass in the diet. No association was found between OC levels and the protected area status of nesting sites. Physiological effects of contaminants were also manifest in increased white blood cell counts with higher p,p'-DDT levels. Heterophil to lymphocyte ratio increased with higher ΣPCB levels, suggesting increased physiological stress and reduced immunity in contaminated individuals. Our results suggest that OCs are still a current cause of concern for endangered Black Harriers, as well as other sympatric predators.
[Mh] Termos MeSH primário: DDT/sangue
Exposição Dietética/análise
Resíduo Eletrônico
Monitoramento Ambiental
Poluentes Ambientais/sangue
Falconiformes/sangue
Bifenilos Policlorados/sangue
[Mh] Termos MeSH secundário: Adulto
África Austral
Animais
Aves
Diclorodifenil Dicloroetileno/sangue
Dieta/estatística & dados numéricos
Exposição Dietética/estatística & dados numéricos
Ecossistema
Seres Humanos
Hidrocarbonetos Clorados/sangue
África do Sul
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Hydrocarbons, Chlorinated); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); CIW5S16655 (DDT); DFC2HB4I0K (Polychlorinated Biphenyls)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171008
[St] Status:MEDLINE


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[PMID]:28934091
[Au] Autor:Cano-Sancho G; Salmon AG; La Merrill MA
[Ad] Endereço:Department of Environmental Toxicology, University of California, Davis , Davis, California, USA.
[Ti] Título:Association between Exposure to '-DDT and Its Metabolite '-DDE with Obesity: Integrated Systematic Review and Meta-Analysis.
[So] Source:Environ Health Perspect;125(9):096002, 2017 Sep 18.
[Is] ISSN:1552-9924
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The prevalence of obesity is increasing in all countries, becoming a substantial public health concern worldwide. Increasing evidence has associated obesity with persistent pollutants such as the pesticide DDT and its metabolite '-DDE. OBJECTIVES: Our objective was to systematically review the literature on the association between exposure to the pesticide DDT and its metabolites and obesity to develop hazard identification conclusions. METHODS: We applied a systematic review-based strategy to identify and integrate evidence from epidemiological, , and studies. The evidence from prospective epidemiological studies was quantitatively synthesized by meta-analysis. We rated the body of evidence and integrated the streams of evidence to systematically develop hazard identification conclusions. RESULTS: We identified seven epidemiological studies reporting prospective associations between exposure to -DDE and adiposity assessed by body mass index (BMI) -score. The results from the meta-analysis revealed positive associations between exposure to -DDE and BMI -score (ß=0.13 BMI -score (95% CI: 0.01, 0.25) per log increase of -DDE). Two studies constituted the primary evidence. Both studies reported positive associations between exposure to -DDT and increased adiposity in rodents. We identified 19 studies and 7 studies that supported the biological plausibility of the obesogenic effects of -DDT and -DDE. CONCLUSIONS: We classified -DDT and -DDE as "presumed" to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary evidence, and a moderate level of supporting evidence from and studies. https://doi.org/10.1289/EHP527.
[Mh] Termos MeSH primário: DDT/metabolismo
Diclorodifenil Dicloroetileno/metabolismo
Exposição Ambiental/estatística & dados numéricos
Poluentes Ambientais/metabolismo
Obesidade/epidemiologia
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Environmental Pollutants); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); CIW5S16655 (DDT)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE
[do] DOI:10.1289/EHP527


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[PMID]:28917205
[Au] Autor:Warner M; Ye M; Harley K; Kogut K; Bradman A; Eskenazi B
[Ad] Endereço:Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA. Electronic address: mwarner@berkeley.edu.
[Ti] Título:Prenatal DDT exposure and child adiposity at age 12: The CHAMACOS study.
[So] Source:Environ Res;159:606-612, 2017 11.
[Is] ISSN:1096-0953
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Using data from the Center for the Health Assessment of Mothers and Children of Salinas (CHAMACOS) birth cohort study, we assessed the association of in utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenylethylene (DDE) with child adiposity at age 12. METHODS: We included 240 children with o,p'-DDT, p,p'-DDT, and p,p'-DDE concentrations measured in maternal serum collected during pregnancy (ng/g lipid) and complete 12-year follow-up data. Age- and sex-specific body mass index (BMI) z-scores were calculated from CDC growth charts. Children with BMI z-scores ≥ 85th percentile were classified as overweight or obese. RESULTS: At 12 years, BMI z-score averaged 1.09 (±1.03) and 55.4% of children were overweight or obese. Prenatal DDT and DDE exposure was associated with several adiposity measures in boys but not girls. Among boys, 10-fold increases in prenatal DDT and DDE concentrations were associated with increased BMI z-score (o,p'-DDT, adj-ß=0.37, 95% CI: 0.08, 0.65; p,p'-DDT, adj-ß = 0.26, 95% CI: 0.03, 0.48; p,p'-DDE, adj-ß = 0.31, 95% CI: 0.02, 0.59). Results for girls were nonsignificant. The difference by sex persisted after considering pubertal status. CONCLUSIONS: These results support the chemical obesogen hypothesis, that in utero exposure to DDT and DDE may increase risk of obesity in males later in life.
[Mh] Termos MeSH primário: Adiposidade/efeitos dos fármacos
DDT/efeitos adversos
Diclorodifenil Dicloroetileno/efeitos adversos
Poluentes Ambientais/efeitos adversos
Exposição Materna/efeitos adversos
[Mh] Termos MeSH secundário: California
Criança
Feminino
Seres Humanos
Inseticidas/efeitos adversos
Estudos Longitudinais
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Insecticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); CIW5S16655 (DDT)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171120
[Lr] Data última revisão:
171120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170917
[St] Status:MEDLINE


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[PMID]:28841520
[Au] Autor:Cupul-Uicab LA; Terrazas-Medina EA; Hernández-Ávila M; Longnecker MP
[Ad] Endereço:Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Morelos 62100, Mexico; Hospital Regional de Alta Especialidad de la Península de Yucatán, Mérida, Yucatán 97130, Mexico.
[Ti] Título:In utero exposure to DDT and incidence of diarrhea among boys from tropical Mexico.
[So] Source:Environ Res;159:331-337, 2017 11.
[Is] ISSN:1096-0953
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: A higher incidence rate (IR) of acute gastrointestinal (GI) infections associated with prenatal exposure to p,p'-DDE was suggested by the results in two studies. Given the high mortality rate due to childhood diarrhea in some countries with ongoing use of DDT, additional data on this association is relevant for those making decisions about vector-borne disease control. OBJECTIVE: To evaluate whether higher levels of prenatal exposure to p,p'-DDE and p,p'-DDT increase the risk of having diarrhea in a birth cohort of boys from tropical Mexico. METHODS: Our analysis was based on 747 boys whose exposure was measured in maternal serum collected at delivery (2002-2003). Mothers reported the number of diarrhea episodes of their children during in-person interviews. The median age of the children at their last interview was 21.4 months. Poisson regression models were fitted to estimate adjusted incidence rate ratios (aIRR) of diarrhea by levels of p,p'-DDE and p,p'-DDT. RESULTS: Overall, there were 1.7 episodes of diarrhea per child-year. Among those in the highest category of exposure (> 9µg DDE/g serum lipid), the aIRR for diarrhea was 1.14 (95% CI: 0.94, 1.30) compared to those in the lowest category of exposure (≤ 3µg/g). Among boys living in the urban area, the corresponding aIRR was 1.39 (95% CI: 1.07-1.80). Among rural boys, no associations emerged. CONCLUSION: Although the results were consistent with a small positive association, the overall estimate was not precise. While urban boys in this study appeared to be more susceptible to DDE-associated diarrhea, a ready explanation for such increased susceptibility was not apparent.
[Mh] Termos MeSH primário: DDT/toxicidade
Diarreia/epidemiologia
Diclorodifenil Dicloroetileno/toxicidade
Poluentes Ambientais/toxicidade
Exposição Materna
Efeitos Tardios da Exposição Pré-Natal/epidemiologia
[Mh] Termos MeSH secundário: Diarreia/induzido quimicamente
Feminino
Seres Humanos
Incidência
Lactente
Recém-Nascido
Inseticidas/toxicidade
Masculino
México/epidemiologia
Gravidez
Efeitos Tardios da Exposição Pré-Natal/induzido quimicamente
Clima Tropical
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, N.I.H., INTRAMURAL
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Insecticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); CIW5S16655 (DDT)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171120
[Lr] Data última revisão:
171120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170826
[St] Status:MEDLINE


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[PMID]:28793859
[Au] Autor:Irving H; Wondji CS
[Ad] Endereço:Vector Biology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
[Ti] Título:Investigating knockdown resistance (kdr) mechanism against pyrethroids/DDT in the malaria vector Anopheles funestus across Africa.
[So] Source:BMC Genet;18(1):76, 2017 Aug 09.
[Is] ISSN:1471-2156
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Understanding the molecular basis of insecticide resistance is key to improve the surveillance and monitoring of malaria vector populations under control. In the major malaria vector Anopheles funestus, little is currently known about the role of the knockdown resistance (kdr) mechanism. Here, we investigated the presence and contribution of knockdown resistance (kdr) to pyrethroids/DDT resistance observed in Anopheles funestus across Africa. RESULTS: Pyrosequencing genotyping and sequencing of the voltage gated sodium channel (VGSC) gene did not detect the common L1014F mutation in field collected An. funestus across Africa. Amplification and cloning of the full-length of the sodium channel gene in pyrethroid resistant mosquitoes revealed evidences of alternative splicing events with three transcripts of 2092, 2061 and 2117 amino acids (93% average similarity to An. gambiae). Several amino acid changes were detected close to the domain II of the protein such as L928R, F938 W, I939S, L802S and T1008 M. However, all these mutations are found at low frequency and their role in pyrethroid resistance could not be established. The presence of the exclusive alternative splicing at exon 19 was not associated with resistance phenotype. Analysis of patterns of genetic diversity of the VGSC gene revealed a high polymorphism level of this gene across Africa with no evidence of directional selection suggesting a limited role for knockdown resistance in pyrethroid resistance in An. funestus. Patterns of genetic differentiation correlate with previous observations of the existence of barriers to gene flow Africa-wide with southern population significantly differentiated from other regions. CONCLUSION: Despite an apparent limited role of knockdown resistance in An. funestus, it is necessary to continue to monitor the contribution of the mutations detected here as increasing selection from insecticide-based interventions may change the dynamic in field populations as previously observed in other vectors.
[Mh] Termos MeSH primário: Anopheles/efeitos dos fármacos
DDT/farmacologia
Insetos Vetores/efeitos dos fármacos
Piretrinas/farmacologia
[Mh] Termos MeSH secundário: África
Processamento Alternativo
Sequência de Aminoácidos
Animais
Anopheles/classificação
Anopheles/genética
Sequência de Bases
Proteínas de Insetos/química
Proteínas de Insetos/genética
Insetos Vetores/genética
Resistência a Inseticidas
Inseticidas/farmacologia
Malária/transmissão
Mutação
Filogenia
Homologia de Sequência
Canais de Sódio Disparados por Voltagem/química
Canais de Sódio Disparados por Voltagem/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insect Proteins); 0 (Insecticides); 0 (Pyrethrins); 0 (Voltage-Gated Sodium Channels); CIW5S16655 (DDT)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1186/s12863-017-0539-x


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[PMID]:28737099
[Au] Autor:Thompson LA; Ikenaka Y; Yohannes YB; van Vuren JJ; Wepener V; Smit NJ; Darwish WS; Nakayama SMM; Mizukawa H; Ishizuka M
[Ad] Endereço:a Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine , Hokkaido University , Sapporo , Japan.
[Ti] Título:Concentrations and human health risk assessment of DDT and its metabolites in free-range and commercial chicken products from KwaZulu-Natal, South Africa.
[So] Source:Food Addit Contam Part A Chem Anal Control Expo Risk Assess;34(11):1959-1969, 2017 Nov.
[Is] ISSN:1944-0057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Organochlorine pesticides such as dichlorodiphenyltrichloroethane (DDT) have been used in agriculture and for disease control purposes over many decades. Reports suggest that DDT exposure may result in a number of adverse effects in humans. In the KwaZulu-Natal Province of South Africa, DDT is sprayed annually in homes (indoor residual spraying) to control the mosquito vector of malaria. In the northern part of the Province, samples of free-range chicken meat (n = 48) and eggs (n = 13), and commercially produced chicken meat (n = 6) and eggs (n = 11), were collected and analysed. Of the free-range chicken meat samples, 94% (45/48) contained DDTs (ΣDDTs median 6.1 ng/g wet weight [ww], maximum 79.1 ng/g ww). Chicken egg contents were also contaminated (ΣDDTs in free-range eggs median 9544 ng/g ww, maximum 96.666 ng/g ww; and in commercial eggs median 1.3 ng/g ww, maximum 4.6 ng/g ww). The predominant DDT congener detected was p,p'-DDE in both free-range meat (>63%) and eggs (>66%), followed by p,p'-DDT and then p,p'-DDD. Based on estimated daily intake values, calculated human risk ratio (carcinogenic) values were >1 for DDTs detected in both free-range chicken products. Consumption of free-range eggs poses a particularly high health risk.
[Mh] Termos MeSH primário: Galinhas
DDT/análise
DDT/metabolismo
Contaminação de Alimentos/análise
Carne/análise
Óvulo/química
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Medição de Risco
África do Sul
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
CIW5S16655 (DDT)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170725
[St] Status:MEDLINE
[do] DOI:10.1080/19440049.2017.1357209


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[PMID]:28696207
[Au] Autor:Gaspar FW; Chevrier J; Quirós-Alcalá L; Lipsitt JM; Barr DB; Holland N; Bornman R; Eskenazi B
[Ad] Endereço:Center for Environmental Research and Children's Health (CERCH), School of Public Health, University of California at Berkeley, Berkeley, California, USA
[Ti] Título:Levels and Determinants of DDT and DDE Exposure in the VHEMBE Cohort.
[So] Source:Environ Health Perspect;125(7):077006, 2017 07 07.
[Is] ISSN:1552-9924
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Although indoor residual spraying (IRS) is an effective tool for malaria control, its use contributes to high insecticide exposure in sprayed communities and raises concerns about possible unintended health effects. OBJECTIVE: The Venda Health Examination of Mothers, Babies and their Environment (VHEMBE) is a birth cohort study initiated in 2012 to characterize prenatal exposure to IRS insecticides and exposures' impacts on child health and development in rural South Africa. METHODS: In this report, we describe the VHEMBE cohort and dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) serum concentrations measured in VHEMBE mothers when they presented for delivery. In addition, we applied a causal inference framework to estimate the potential reduction in population-level , -DDT and , -DDE serum concentrations under five hypothetical interventions. A total of 751 mothers were enrolled. RESULTS: Serum concentrations of , isomers of DDT and DDE were above the limit of detection (LOD) in ≥98% of the samples, whereas the , isomers were above the LOD in at least 80% of the samples. Median (interquartile range) , -DDT and , -DDE serum concentrations for VHEMBE cohort participants were 55.3 (19.0-259.3) and 242.2 (91.8-878.7) ng/g-lipid, respectively. Mothers reporting to have lived in a home sprayed with DDT for malaria control had ~5-7 times higher , -DDT and , -DDE serum concentrations than those who never lived in a home sprayed with DDT. Of the five potential interventions tested, we found increasing access to water significantly reduced , -DDT exposure and increasing the frequency of household wet mopping significantly reduced , -DDT and , -DDE exposure. CONCLUSION: Our findings suggest that several intervention approaches may reduce DDT/DDE exposure in pregnant women living in IRS communities. https://doi.org/10.1289/EHP353.
[Mh] Termos MeSH primário: DDT/sangue
Diclorodifenil Dicloroetileno/sangue
Inseticidas/sangue
Exposição Materna
[Mh] Termos MeSH secundário: Adolescente
Adulto
Estudos de Coortes
DDT/química
Diclorodifenil Dicloroetileno/química
Feminino
Seres Humanos
Inseticidas/química
Gravidez
África do Sul
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); CIW5S16655 (DDT)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170712
[St] Status:MEDLINE
[do] DOI:10.1289/EHP353


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[PMID]:28628635
[Au] Autor:E Pereira A; Souza D; Zukoff SN; Meinke LJ; Siegfried BD
[Ad] Endereço:Division of Plant Sciences, University of Missouri, Columbia, Missouri, United States of America.
[Ti] Título:Cross-resistance and synergism bioassays suggest multiple mechanisms of pyrethroid resistance in western corn rootworm populations.
[So] Source:PLoS One;12(6):e0179311, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Recently, resistance to the pyrethroid bifenthrin was detected and confirmed in field populations of western corn rootworm, Diabrotica virgifera virgifera LeConte from southwestern areas of Nebraska and Kansas. As a first step to understand potential mechanisms of resistance, the objectives of this study were i) to assess adult mortality at diagnostic concentration-LC99 to the pyrethroids bifenthrin and tefluthrin as well as DDT, ii) estimate adult and larval susceptibility to the same compounds as well as the organophosphate methyl-parathion, and iii) perform synergism experiments with piperonyl butoxide (PBO) (P450 inhibitor) and S,S,S-tributyl-phosphorotrithioate (DEF) (esterase inhibitor) in field populations. Most of the adult field populations exhibiting some level of bifenthrin resistance exhibited significantly lower mortality to both pyrethroids and DDT than susceptible control populations at the estimated LC99 of susceptible populations. Results of adult dose-mortality bioassays also revealed elevated LC50 values for bifenthrin resistant populations compared to the susceptible control population with resistance ratios ranging from 2.5 to 5.5-fold for bifenthrin, 28 to 54.8-fold for tefluthrin, and 16.3 to 33.0 for DDT. These bioassay results collectively suggest some level of cross-resistance between the pyrethroids and DDT. In addition, both PBO and DEF reduced the resistance ratios for resistant populations although there was a higher reduction in susceptibility of adults exposed to PBO versus DEF. Susceptibility in larvae varied among insecticides and did not correlate with adult susceptibility to tefluthrin and DDT, as most resistance ratios were < 5-fold when compared to the susceptible population. These results suggest that both detoxifying enzymes and target site insensitivity might be involved as resistance mechanisms.
[Mh] Termos MeSH primário: Coleópteros
Resistência a Inseticidas/efeitos dos fármacos
Inseticidas
Piretrinas
Zea mays/parasitologia
[Mh] Termos MeSH secundário: Animais
Bioensaio
Coleópteros/crescimento & desenvolvimento
Ciclopropanos
DDT
Sinergismo Farmacológico
Hidrocarbonetos Fluorados
Larva
Dose Letal Mediana
Compostos Organotiofosforados
Butóxido de Piperonila
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cyclopropanes); 0 (Hydrocarbons, Fluorinated); 0 (Insecticides); 0 (Organothiophosphorus Compounds); 0 (Pyrethrins); 2HE8P42H2J (2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate); 6B66JED0KN (bifenthrin); CIW5S16655 (DDT); LWK91TU9AH (Piperonyl Butoxide); RN743HTX76 (merphos)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179311


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[PMID]:28540444
[Au] Autor:Al Antary TM; Alawi MA; Estityah H; Haddad N
[Ad] Endereço:Department of Plant Protection, School of Agriculture, University of Jordan, Amman, 11942, Jordan.
[Ti] Título:Organochlorine Pesticides Residues in Human Breast Milk from the Middle Governorates in Jordan in 2013/2014.
[So] Source:Bull Environ Contam Toxicol;99(1):89-92, 2017 Jul.
[Is] ISSN:1432-0800
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:One hundred samples of mother breast milk were gathered from six middle governorates and districts in Jordan in 2013/2014 to monitor Organochlorine pesticides pollutants. The results showed clearly that banned organochlorine pesticides are still detected in the monitored samples in low concentration despite banning of these persistent pollutants in Jordan since 36 years ago. However, the results indicated that 1% of the contaminated samples contained ß-HCH, 5% γ-HCH, 3% p,p'-DDD, 2% heptachlor, 45% p,p'-DDE and 3% p,p'-DDT. In addition, these monitored samples had no residues of aldrin, dieldrin, α-endosulfan, ß-endosulfan, HCB, o,p'-DD, o,p'-DDT and o,p'-DDE. In conclusion, there was a decline in the residues of Organochlorine pesticides, particularly DDT group members.
[Mh] Termos MeSH primário: Exposição Ambiental/estatística & dados numéricos
Hidrocarbonetos Clorados/metabolismo
Leite Humano/metabolismo
Resíduos de Praguicidas/metabolismo
Praguicidas/metabolismo
[Mh] Termos MeSH secundário: Aldrina/análise
Aldrina/metabolismo
DDT
Diclorodifenil Dicloroetileno/análise
Diclorodifenil Dicloroetileno/metabolismo
Dieldrin/análise
Dieldrin/metabolismo
Endossulfano/análise
Endossulfano/metabolismo
Heptacloro/análise
Heptacloro/metabolismo
Seres Humanos
Hidrocarbonetos Clorados/análise
Jordânia
Lindano/metabolismo
Leite Humano/química
Mitotano/análogos & derivados
Mitotano/metabolismo
Resíduos de Praguicidas/análise
Praguicidas/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Pesticide Residues); 0 (Pesticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); 59NEE7PCAB (Lindane); 78E4J5IB5J (Mitotane); 7GLS9ACN3L (Heptachlor); CIW5S16655 (DDT); D4K93Z1TBH (o,p'-DDT); DM084YLQ1L (2,2-(2-chlorophenyl-4'-chlorophenyl)-1,1-dichloroethene); I0246D2ZS0 (Dieldrin); OKA6A6ZD4K (Endosulfan); OZE3CLY605 (Aldrin); YM80ODM9PD (beta-hexachlorocyclohexane)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170526
[St] Status:MEDLINE
[do] DOI:10.1007/s00128-017-2117-3


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[PMID]:28525872
[Au] Autor:Campillo JA; Fernández B; García V; Benedicto J; León VM
[Ad] Endereço:Instituto Español de Oceanografía (IEO), Oceanographic Centre of Murcia, Varadero 1, 30740, San Pedro del Pinatar, Murcia, Spain. Electronic address: juan.campillo@mu.ieo.es.
[Ti] Título:Levels and temporal trends of organochlorine contaminants in mussels from Spanish Mediterranean waters.
[So] Source:Chemosphere;182:584-594, 2017 Sep.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The levels and trends of organochlorine contaminants were determined along the Spanish Mediterranean coast from 2000 to 2013 using mussel, Mytilus galloprovincialis, as bioindicator species. The highest levels of PCBs and DDTs were found at industrial and urban locations, and at areas under the influence of the mouth of major rivers. Dieldrin and t-NNC were commonly detected, while HCHs, aldrin, isodrin, endrin and HCB were at levels not detectable at many areas. Significant declines on the levels of DDTs were observed at most of the areas studied. Conversely, no trends or weak downtrends for PCBs were observed in the areas more polluted by local sources, and in most areas less polluted, where PCBs inputs may be primarily from the atmosphere. Upward trends for PCBs were found in some areas from the Alborán Sea, probably related to the inputs of PCBs through the Strait of Gibraltar. Background concentrations for PCBs and p,p'-DDE have been calculated for this Mediterranean region.
[Mh] Termos MeSH primário: Monitoramento Ambiental
Mytilus/química
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Animais
DDT/análise
Hidrocarbonetos Clorados/análise
Região do Mediterrâneo
Bifenilos Policlorados/análise
Frutos do Mar
Espanha
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Water Pollutants, Chemical); CIW5S16655 (DDT); DFC2HB4I0K (Polychlorinated Biphenyls)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170922
[Lr] Data última revisão:
170922
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE



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