Base de dados : MEDLINE
Pesquisa : D02.455.526.439.659 [Categoria DeCS]
Referências encontradas : 354 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 36 ir para página                         

  1 / 354 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27888061
[Au] Autor:Wrobel MH; Mlynarczuk J
[Ad] Endereço:Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima Street 10, 10-748 Olsztyn, Poland. Electronic address: m.wrobel@pan.olsztyn.pl.
[Ti] Título:Secretory function of ovarian cells and myometrial contractions in cow are affected by chlorinated insecticides (chlordane, heptachlor, mirex) in vitro.
[So] Source:Toxicol Appl Pharmacol;314:63-71, 2017 Jan 01.
[Is] ISSN:1096-0333
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The aim of the study was to investigate the effect of chlordane, heptachlor and mirex, on hormonal regulation of the force of myometrial contractions. Myometrial, endometrial, granulosa and luteal cells as well as strips of myometrium from non-pregnant cows were incubated with three insecticides at environmentally relevant doses (0.1, 1 or 10ng/ml). None of the insecticides affected the viability of studied cells. Chlordane stimulated, while heptachlor and mirex inhibited, secretion of testosterone and estradiol from granulosa cells as well as secretion of progesterone from luteal cells, respectively. Secretion of oxytocin (OT) from granulosa cells was increased after incubation with all studied insecticides. Only mirex stimulated OT secretion from luteal cells, while heptachlor inhibited this effect. None of them affected synthesis of OT in luteal cells and prostaglandins (PGF2 and PGE2) secretion from uterine cells, except PGE2 secretion from endometrial cells was decreased when the cells were incubated with 0.1ng/ml of chlordane. Basal and OT-stimulated myometrial contractions were increased by mirex and decreased by heptachlor. The data show that the insecticides altered secretory function of ovarian cells. Heptachlor and mirex affected also myometrial contractions in vitro, but uterine secretion of prostaglandins were not involved in the mechanism of that adverse effect of insecticides. The data indicate on potential of these insecticides to disturb fertilisation, blastocyst implantation or even the length of gestation.
[Mh] Termos MeSH primário: Clordano/toxicidade
Heptacloro/toxicidade
Inseticidas/toxicidade
Mirex/toxicidade
Ovário/efeitos dos fármacos
Contração Uterina/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Bovinos
Feminino
Técnicas In Vitro
Ovário/secreção
Gravidez
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 12789-03-6 (Chlordan); 7GLS9ACN3L (Heptachlor); Z917AN264P (Mirex)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170523
[Lr] Data última revisão:
170523
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161127
[St] Status:MEDLINE


  2 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26943594
[Au] Autor:Aminov Z; Haase R; Carpenter DO
[Ti] Título:Diabetes in Native Americans: elevated risk as a result of exposure to polychlorinated biphenyls (PCBs).
[So] Source:Rev Environ Health;31(1):115-9, 2016 Mar.
[Is] ISSN:2191-0308
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:We have studied rates of diabetes in 601 members of the Mohawk Nation at Akwesasne, ages 18-84 years, in relation to serum concentrations of 101 polychlorinated biphenyl (PCB) congeners and three chlorinated pesticides [dichlorodiphenyldichloroethylene (DDE), hexachlorobenzene (HCB) and mirex]. Diabetes was determined from either a diagnosis by a physician or by having a fasting glucose concentration of >125 mg/dL. Rates of diabetes are high in this community. Three models were used. In the first model rate ratios (RR) were determined for quartiles of total PCBs after adjustment for age, sex, body mass index (BMI) and total serum lipids. For total PCBs RR=2.21 (1.2-4.2), while for total pesticides RR=3.75 (1.3-10.7). When the total PCB results were also adjusted for total pesticides and the total pesticide results were also adjusted for total PCBs (Model 2) the RRs were somewhat reduced. In Model 3 we considered subgroups of PCBs based on numbers of chlorines on the molecule (tri-/tetra, penta-/hexa, hepta plus) and numbers of ortho chlorines (non-/mono; di-, tri-/tetra-), and considered each of the pesticides individually after adjustment for all other contaminants as well as age, sex, BMI and serum lipids. We found a highly significant association between diabetes and PCBs with only three or four chlorines (RR=5.02), but no significant association with those with greater chlorination. When evaluating PCBs based on numbers of ortho chlorines only, those with no or one ortho chlorine showed significant associations. As mono-ortho PCBs include some with dioxin-like activity, we compared those with and without a TEF, and found that the association with diabetes was exclusively with the non-dioxin-like congeners. Of the pesticides only hexachlorobenzene showed a small but significant association with diabetes. Because lower chlorinated PCBs are more volatile and do not greatly accumulate in fish, these results suggest that inhalation is the major route of exposure to those PCBs that increase risk of diabetes.
[Mh] Termos MeSH primário: Diabetes Mellitus/epidemiologia
Exposição Ambiental
Poluentes Ambientais/sangue
Fungicidas Industriais/sangue
Inseticidas/sangue
Bifenilos Policlorados/sangue
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Diabetes Mellitus/etiologia
Diclorodifenil Dicloroetileno/sangue
Feminino
Hexaclorobenzeno/sangue
Seres Humanos
Índios Norte-Americanos
Masculino
Meia-Idade
Mirex/sangue
Modelos Teóricos
New York/epidemiologia
Obesidade/epidemiologia
Obesidade/etiologia
Sobrepeso/epidemiologia
Sobrepeso/etiologia
Prevalência
Fatores de Risco
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Fungicides, Industrial); 0 (Insecticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); 4Z87H0LKUY (Hexachlorobenzene); DFC2HB4I0K (Polychlorinated Biphenyls); Z917AN264P (Mirex)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160305
[St] Status:MEDLINE


  3 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25410309
[Au] Autor:Yu D; Yang J; Li T; Feng J; Xian Q; Zhu J
[Ad] Endereço:State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, 210023, People's Republic of China.
[Ti] Título:Levels and distribution of dechloranes in sediments of Lake Taihu, China.
[So] Source:Environ Sci Pollut Res Int;22(9):6601-9, 2015 May.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The occurrence and spatial distribution of dechloranes including mirex, dechlorane plus (DP), dechlorane (Dec) 602, Dec 603, and Dec 604 in surficial sediments of Lake Taihu were investigated in this study. The concentrations of mirex and DP ranged from below detection limit (BDL) to 1.29 ng g(-1) dw and 0.051 to 2.10 ng g(-1) dw, respectively. Dec 602, Dec 603, and Dec 604 on the other hand, were BDL in any of the samples. The contamination levels of DP were higher than that of Mirex at 21 of all 22 sampling sites. Levels of mirex and DP in the lake sediments were correlated when an extremely high mirex value was removed. Both mirex and DP levels were correlated with the amount of organic matters in the sediment samples. Spatial distribution of mirex and DP suggested that these two chemicals in the lake had similar input sources except for one site. Comparison to previously reported flame retardants' levels in the sediments shows that DP levels were similar with the levels of tetrabromobisphenol A, hexabromocyclododecane but lower than PBDEs and organophosphates levels in Lake Taihu. The higher levels in the north-east part of Lake Taihu adjacent to two major cities: Wuxi and Suzhou, indicated that city effluent might be a major source for DP contamination in the lake.
[Mh] Termos MeSH primário: Monitoramento Ambiental/métodos
Sedimentos Geológicos/química
Hidrocarbonetos Clorados/análise
Lagos/química
Mirex/análise
Compostos Policíclicos/análise
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: China
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Polycyclic Compounds); 0 (Water Pollutants, Chemical); 0 (dechlorane plus); Z917AN264P (Mirex)
[Em] Mês de entrada:1508
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141121
[St] Status:MEDLINE
[do] DOI:10.1007/s11356-014-3794-7


  4 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25184555
[Au] Autor:Shen L; Jobst KJ; Reiner EJ; Helm PA; McCrindle R; Taguchi VY; Marvin CH; Backus S; MacPherson KA; Brindle ID
[Ad] Endereço:Department of Chemistry, Brock University , 500 Glenridge Avenue, St. Catharines, Ontario Canada L2S 3A1.
[Ti] Título:Identification and occurrence of analogues of dechlorane 604 in Lake Ontario sediment and their accumulation in fish.
[So] Source:Environ Sci Technol;48(19):11170-7, 2014 Oct 07.
[Is] ISSN:1520-5851
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The dechlorane family of flame retardants, which includes Mirex (also known as Dechlorane), Dechlorane Plus (DP), and Dechloranes (Dec) 602, 603, and 604, were manufactured at a facility along the Niagara River, upstream of Lake Ontario. Some of these compounds remain in use. In a previous study, we found Mirex and Dec602 to have greater bioaccumulation potentials than Dec604 and DP based on calculated biota-sediment accumulation factors (BSAFs). In this study, analogues of Dec604, containing fewer bromines and mixed substitutions of bromine and chlorine, were identified in Lake Ontario sediment and fish using high and ultrahigh resolution mass spectrometric techniques. The tribromo-Dec604 (Br3Dec604) analogue, known as Dechlorane 604 Component B (Dec604 CB), was present in lake trout and whitefish at concentrations of 10-60 ng/g lipid weight, approximately 50-200 times greater than concentrations measured for Dec604. In addition, BrDec604 and Br2Dec604 analogues, and mixed Br2Cl2Dec604, Br3ClDec604, Br2ClDec604, and BrCl2Dec604 analogues were also present. We have shown that solutions of Dec604 and Dec604 CB exposed to UV-light undergo photodebromination and give rise to the analogues found in sediment and fish. Dec604 CB and other lesser halogenated analogues of Dec604 show greater bioaccumulation potentials than Dec604, Dec602 and DP, based on BSAFs, which highlight the need to consider likely impurities and degradation products in the assessment of persistent, bioaccumulative, and toxic compounds.
[Mh] Termos MeSH primário: Peixes/metabolismo
Retardadores de Chama/metabolismo
Hidrocarbonetos Clorados/análise
Hidrocarbonetos Clorados/metabolismo
Poluentes Químicos da Água/metabolismo
[Mh] Termos MeSH secundário: Animais
Monitoramento Ambiental
Retardadores de Chama/análise
Sedimentos Geológicos/química
Hidrocarbonetos Clorados/química
Hidrocarbonetos Clorados/efeitos da radiação
Lagos
Mirex/análise
Mirex/metabolismo
Ontário
Compostos Policíclicos/análise
Compostos Policíclicos/metabolismo
Salmonidae
Truta
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Flame Retardants); 0 (Hydrocarbons, Chlorinated); 0 (Polycyclic Compounds); 0 (Water Pollutants, Chemical); 0 (dechlorane 602); 0 (dechlorane 604); Z917AN264P (Mirex)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:141007
[Lr] Data última revisão:
141007
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140904
[St] Status:MEDLINE
[do] DOI:10.1021/es503089c


  5 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:25066456
[Au] Autor:Gui D; Yu R; He X; Tu Q; Wu Y
[Ad] Endereço:Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, School of Marine Sciences, Sun Yat-Sen University, Guangzhou 510275, China.
[Ti] Título:Tissue distribution and fate of persistent organic pollutants in Indo-Pacific humpback dolphins from the Pearl River Estuary, China.
[So] Source:Mar Pollut Bull;86(1-2):266-273, 2014 Sep 15.
[Is] ISSN:1879-3363
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Eleven persistent organic pollutant (POP) compounds including ∑PCBs, ∑DDTs, ∑HCHs, aldrin, mirex, endrin, ∑CHLs, dieldrin, HCB, heptachlor and pentachlorobenzene were measured in the kidney, liver, muscle, melon and other tissues of Sousa chinensis stranded on the western coast of the Pearl River Estuary in China during 2007-2013. For most parameters of POPs measured, melon tissues contained the highest mean concentrations with the exception of aldrin, which was higher in the kidney and liver tissues. The concentrations of PCBs, DDTs, heptachlor and endrin in the melon tissue exhibited significant correlations with body length, whereas PCBs and heptachlor also displayed significant regression with age. Our studies showed hepatic concentrations of ∑DDTs, ∑HCHs and mirex in S. chinensis were generally higher than those found in cetaceans from other geographic locations. The high levels of POP residues in the testis of one male dolphin suggested an increasing risk of infertility in the species.
[Mh] Termos MeSH primário: Golfinhos/metabolismo
Estuários
Hidrocarbonetos Clorados/metabolismo
Hidrocarbonetos Clorados/farmacocinética
Poluentes Químicos da Água/metabolismo
Poluentes Químicos da Água/farmacocinética
[Mh] Termos MeSH secundário: Fatores Etários
Aldrina/farmacocinética
Animais
China
Clorobenzenos/farmacocinética
Dieldrin/farmacocinética
Endrin/farmacocinética
Geografia
Heptacloro/farmacocinética
Rim/metabolismo
Fígado/metabolismo
Masculino
Mirex/farmacocinética
Músculo Esquelético/metabolismo
Bifenilos Policlorados/farmacocinética
Testículo/metabolismo
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Chlorobenzenes); 0 (Hydrocarbons, Chlorinated); 0 (Water Pollutants, Chemical); 7GLS9ACN3L (Heptachlor); D62GWO6832 (pentachlorobenzene); DFC2HB4I0K (Polychlorinated Biphenyls); I0246D2ZS0 (Dieldrin); OB9NVE7YCL (Endrin); OZE3CLY605 (Aldrin); Z917AN264P (Mirex)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140729
[St] Status:MEDLINE


  6 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:24880592
[Au] Autor:Guo H; Jin Y; Cheng Y; Leaderer B; Lin S; Holford TR; Qiu J; Zhang Y; Shi K; Zhu Y; Niu J; Bassig BA; Xu S; Zhang B; Li Y; Hu X; Chen Q; Zheng T
[Ad] Endereço:Yale School of Public Health, New Haven, CT 06510, USA; School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China.
[Ti] Título:Prenatal exposure to organochlorine pesticides and infant birth weight in China.
[So] Source:Chemosphere;110:1-7, 2014 Sep.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In utero exposure to organochlorine pesticides (OCPs) is thought to be potentially harmful to fetal development. We aimed to investigate the associations of maternal and cord serum OCPs levels with infant birth weight in China. In this study, we measured serum levels of 18 OCPs in 81 mother-infant pairs, including DDT, hexachlorocyclohexanes (BHC), hexachlorobenzene (HCB), heptachlors, chlordanes, endosulfan-I, and mirex using a high-resolution-gas-chromatography with high-resolution-mass-spectrometry method. We found that p,p'-DDE and ß-BHC had the highest detection rate in both maternal and cord blood serum (97.2% and 96.7%, respectively), followed by HCB (93.0%, 51.7%), p,p'-DDT (88.7%, 36.7%), and p,p'-DDD (83.1%, 60.0%). Among all OCPs, the concentration of p,p'-DDE was the highest (mothers geometric mean (GM): 203.54ngg(-1), newborns GM: 116.14ngg(-1)), followed by HCB (70.62ngg(-1), 65.16ngg(-1)), and ß-BHC (67.67ngg(-1), 33.39ngg(-1)). Multiple linear regression analyses showed that each 1ngg(-1) increment of cord serum p,p'-DDE, total DDT, and ß-BHC was associated with a 0.10g, 0.10g, and 0.92g decrease in infant birth weight, respectively, and as the cord serum concentrations of p,p'-DDT, p,p'-DDD, HCB and mirex increased, the infant birth weight was also decreased, although the associations were not statistically significant due to the relatively small sample size. These results suggest that p,p'-DDE, ß-BHC, and HCB were the predominant OCPs in the serum of Chinese pregnant women and cord blood of their newborns. Prenatal exposure to DDT, ß-BHC, HCB, and mirex were associated with a decrease in birth weight, but these results need validation in larger sample-sized studies.
[Mh] Termos MeSH primário: Peso ao Nascer/efeitos dos fármacos
Hidrocarbonetos Clorados/sangue
Praguicidas/sangue
Efeitos Tardios da Exposição Pré-Natal/induzido quimicamente
[Mh] Termos MeSH secundário: Adolescente
Adulto
China
DDT/sangue
Diclorodifenil Dicloroetileno/sangue
Endossulfano/sangue
Feminino
Sangue Fetal/química
Hexaclorobenzeno/sangue
Seres Humanos
Recém-Nascido
Lindano/sangue
Masculino
Exposição Materna
Troca Materno-Fetal
Mirex/sangue
Gravidez
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Pesticides); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); 4Z87H0LKUY (Hexachlorobenzene); 59NEE7PCAB (Lindane); CIW5S16655 (DDT); OKA6A6ZD4K (Endosulfan); Z917AN264P (Mirex)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140602
[St] Status:MEDLINE


  7 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24835686
[Au] Autor:Kim J; Son MH; Kim J; Suh J; Kang Y; Chang YS
[Ad] Endereço:School of Environmental Science and Engineering, Pohang University of Science and Technology (POSTECH), San 31, Hyoja-dong, Nam-gu, Pohang 790-784, Republic of Korea.
[Ti] Título:Assessment of Dechlorane compounds in foodstuffs obtained from retail markets and estimates of dietary intake in Korean population.
[So] Source:J Hazard Mater;275:19-25, 2014 Jun 30.
[Is] ISSN:1873-3336
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A total of 175 samples, composed of 35 different foodstuffs, were obtained from retail markets in Korea and analyzed to investigate the contamination status and dietary intake of Dechlorane compounds. The concentrations of Dechlorane Plus (DP), mirex, Dechlorane (Dec) 602 and 603 ranged from ND to 169.85 pg/g wet weight (ww), 107.30 pg/g ww, 20.81 pg/g ww, 0.41 pg/g ww, respectively, while Dechlorane (Dec) 604 was not detected in any samples. Strong correlations between anti- and syn-DP and between mirex and Dec 602 were observed. The average anti-isomer fractional abundance (fanti) was 0.78±0.11 which was larger than the technical DP value (fanti=0.75). The estimated dietary daily intake of DP, 11.2×10(3) pg/day, was one to three orders of magnitude higher than other Dechloranes. Grain was the most contributed food group to dietary daily intake of DP for Korean population.
[Mh] Termos MeSH primário: Poluentes Ambientais/análise
Retardadores de Chama/análise
Contaminação de Alimentos/análise
[Mh] Termos MeSH secundário: Dieta
Monitoramento Ambiental
Seres Humanos
Hidrocarbonetos Clorados/análise
Mirex/análise
Compostos Policíclicos/análise
República da Coreia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Flame Retardants); 0 (Hydrocarbons, Chlorinated); 0 (Polycyclic Compounds); 0 (dechlorane 602); 0 (dechlorane 603); 0 (dechlorane 604); 0 (dechlorane plus); Z917AN264P (Mirex)
[Em] Mês de entrada:1501
[Cu] Atualização por classe:140610
[Lr] Data última revisão:
140610
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140520
[St] Status:MEDLINE


  8 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24291562
[Au] Autor:Santos-Neto EB; Azevedo-Silva CE; Bisi TL; Santos J; Meirelles AC; Carvalho VL; Azevedo AF; Guimarães JE; Lailson-Brito J
[Ad] Endereço:Laboratório de Mamíferos Aquáticos e Bioindicadores Professora Izabel Gurgel (MAQUA), Faculdade de Oceanografia, Universidade do Estado do Rio de Janeiro, Brazil; Programa de Pós-graduação em Saúde Animal nos Trópicos, Escola de Medicina Veterinária e Zootecnia, Universidade Federal da Bahia, Brazil
[Ti] Título:Organochlorine concentrations (PCBs, DDTs, HCHs, HCB and MIREX) in delphinids stranded at the northeastern Brazil.
[So] Source:Sci Total Environ;472:194-203, 2014 Feb 15.
[Is] ISSN:1879-1026
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Organochlorine compounds are highly persistent in the environment, causing bioaccumulation and biomagnification through the marine food chain. To verify the bioaccumulation pattern of DDT and its metabolites, as well as PCBs, Mirex, HCHs and HCB, samples of subcutaneous adipose tissue from 25 Guiana dolphins (Sotalia guianensis), two Fraser's dolphins (Lagenodelphis hosei), two spinner dolphins (Stenella longirostris), one spotted dolphin (Stenella frontalis), and one striped dolphin (Stenella coeruleoalba) were analyzed. The collected specimens were found stranded in northeastern Brazil between 2005 and 2011. The concentrations were reported in µg·g(-1) lip, varying from 0.02 to 17.3 for ΣPCB, from 0.003 to 5.19 for ΣDDT, from 0.005 to 0.16 for ΣHCH, from 0.002 to 0.16 for HCB, and from 0.02 to 2.38 for Mirex. The PCBs dominated the bioaccumulation pattern for both the Guiana and spinner dolphins; for the other species, DDT was the major compound. A discriminant function analysis revealed the differences in the organochlorine accumulation patterns between the Guiana dolphin (S. guianensis) and the continental shelf/oceanic dolphins (S. frontalis and S. longirostris). The results also show that the concentrations of organochlorine compounds found in the delphinids in northeastern Brazil were lower than the delphinids found in other regions of Brazil, as well as other locations worldwide with intense agroindustrial development and/or a larger population.
[Mh] Termos MeSH primário: Golfinhos/metabolismo
Monitoramento Ambiental
Hidrocarbonetos Clorados/metabolismo
Poluentes Químicos da Água/metabolismo
[Mh] Termos MeSH secundário: Animais
Brasil
DDT/metabolismo
Feminino
Hexaclorobenzeno/metabolismo
Lindano/metabolismo
Masculino
Mirex/metabolismo
Bifenilos Policlorados/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Hydrocarbons, Chlorinated); 0 (Water Pollutants, Chemical); 4Z87H0LKUY (Hexachlorobenzene); 59NEE7PCAB (Lindane); CIW5S16655 (DDT); DFC2HB4I0K (Polychlorinated Biphenyls); Z917AN264P (Mirex)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:140127
[Lr] Data última revisão:
140127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131203
[St] Status:MEDLINE


  9 / 354 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:24080003
[Au] Autor:Ochiai S; Shimojo N; Yuka I; Watanabe M; Matsuno Y; Suzuki S; Kohno Y; Mori C
[Ad] Endereço:Department of Bioenvironmental Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan; Centre for Preventive Medical Science, Chiba University, Chiba 260-8670, Japan.
[Ti] Título:A pilot study for foetal exposure to multiple persistent organic pollutants and the development of infant atopic dermatitis in modern Japanese society.
[So] Source:Chemosphere;94:48-52, 2014 Jan.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Increasing evidence supports that harmful chemicals accumulating in the human body may pose a significant threat to infant health through foetal exposure. Persistent organic pollutants (POPs) are thought to enhance the risk for later development of allergic disease like atopic dermatitis (AD). However, few studies have evaluated the effect of foetal exposure to various POPs on the development of AD in early infancy. Here, we describe the impact of foetal exposure to a number of POPs on the occurrence of AD in 7-month-old infants. The participants were 81 infants with or without AD who participated in a birth cohort study, where the concentrations of 15 polychlorinated biphenyl (PCBs) congeners, dichlorodiphenyltrichloroethane (p,p'-DDT), dichlorodiphenyldichloroethylene (p,p'-DDE), ß-hexachlorocyclohexane (ß-HCH), hexachlorobenzene (HCB), cis-nonachlor, trans-nonachlor, mirex, oxychlordane, and 27 polybrominated diphenyl ether (PBDEs) congeners were measured in the umbilical cord tissues collected immediately after birth. At 7 months, 27 of the 81 infants (33.8%) were diagnosed with AD. Of all POPs examined, total concentrations of 27 PBDE congeners were associated with a significantly decreased incidence of AD. Notably, the concentration of 27 PBDEs was significantly lower in AD infants than in non-AD infants (P<0.01), and the risk of AD development decreased with increasing PBDE levels. These results suggest that foetal exposure to PBDEs is a possible contributing factor to reducing AD in early infancy.
[Mh] Termos MeSH primário: Dermatite Atópica/epidemiologia
Exposição Ambiental/análise
Poluentes Ambientais/metabolismo
[Mh] Termos MeSH secundário: Clordano/análogos & derivados
Clordano/metabolismo
DDT/metabolismo
Dermatite Atópica/induzido quimicamente
Dermatite Atópica/metabolismo
Diclorodifenil Dicloroetileno/metabolismo
Exposição Ambiental/estatística & dados numéricos
Poluentes Ambientais/análise
Feminino
Hexaclorobenzeno/metabolismo
Seres Humanos
Hidrocarbonetos Clorados/metabolismo
Lactente
Recém-Nascido
Japão
Lindano/metabolismo
Masculino
Exposição Materna/estatística & dados numéricos
Mirex/metabolismo
Projetos Piloto
Bifenilos Policlorados/metabolismo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Hydrocarbons, Chlorinated); 12789-03-6 (Chlordan); 27304-13-8 (oxychlordane); 3734-49-4 (nonachlor); 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene); 4Z87H0LKUY (Hexachlorobenzene); 59NEE7PCAB (Lindane); CIW5S16655 (DDT); DFC2HB4I0K (Polychlorinated Biphenyls); YM80ODM9PD (beta-hexachlorocyclohexane); Z917AN264P (Mirex)
[Em] Mês de entrada:1408
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131002
[St] Status:MEDLINE


  10 / 354 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
PubMed Central Texto completo
Texto completo
[PMID]:24192044
[Au] Autor:Upson K; De Roos AJ; Thompson ML; Sathyanarayana S; Scholes D; Barr DB; Holt VL
[Ad] Endereço:Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA.
[Ti] Título:Organochlorine pesticides and risk of endometriosis: findings from a population-based case-control study.
[So] Source:Environ Health Perspect;121(11-12):1319-24, 2013 Nov-Dec.
[Is] ISSN:1552-9924
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Endometriosis is considered an estrogen-dependent disease. Persistent environmental chemicals that exhibit hormonal properties, such as organochlorine pesticides (OCPs), may affect endometriosis risk. OBJECTIVE: We investigated endometriosis risk in relation to environmental exposure to OCPs. METHODS: We conducted the present analyses using data from the Women's Risk of Endometriosis (WREN) study, a population-based case-control study of endometriosis conducted among 18- to 49-year-old female enrollees of a large health care system in western Washington State. OCP concentrations were measured in sera from surgically confirmed endometriosis cases (n = 248) first diagnosed between 1996 and 2001 and from population-based controls (n = 538). We estimated odds ratios (OR) and 95% CIs using unconditional logistic regression, adjusting for age, reference date year, serum lipids, education, race/ethnicity, smoking, and alcohol intake. RESULTS: Our data suggested increased endometriosis risk associated with serum concentrations of ß-hexachlorocyclohexane (HCH) (third vs. lowest quartile: OR = 1.7; 95% CI: 1.0, 2.8; highest vs. lowest quartile OR = 1.3; 95% CI: 0.8, 2.4) and mirex (highest vs. lowest category: OR = 1.5; 95% CI: 1.0, 2.2). The association between serum ß-HCH concentrations and endometriosis was stronger in analyses restricting cases to those with ovarian endometriosis (third vs. lowest quartile: OR = 2.5; 95% CI: 1.5, 5.2; highest vs. lowest quartile: OR = 2.5; 95% CI: 1.1, 5.3). CONCLUSIONS: In our case-control study of women enrolled in a large health care system in the U.S. Pacific Northwest, serum concentrations of ß-HCH and mirex were positively associated with endometriosis. Extensive past use of environmentally persistent OCPs in the United States or present use in other countries may affect the health of reproductive-age women.
[Mh] Termos MeSH primário: Disruptores Endócrinos/toxicidade
Endometriose/induzido quimicamente
Endometriose/epidemiologia
Exposição Ambiental/análise
Hidrocarbonetos Clorados/toxicidade
Praguicidas/toxicidade
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Estudos de Casos e Controles
Disruptores Endócrinos/sangue
Feminino
Cromatografia Gasosa-Espectrometria de Massas
Seres Humanos
Hidrocarbonetos Clorados/sangue
Lindano/sangue
Lindano/toxicidade
Lipídeos/sangue
Modelos Logísticos
Meia-Idade
Mirex/sangue
Mirex/toxicidade
Razão de Chances
Praguicidas/sangue
Fatores de Risco
Washington/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Endocrine Disruptors); 0 (Hydrocarbons, Chlorinated); 0 (Lipids); 0 (Pesticides); 59NEE7PCAB (Lindane); YM80ODM9PD (beta-hexachlorocyclohexane); Z917AN264P (Mirex)
[Em] Mês de entrada:1407
[Cu] Atualização por classe:161128
[Lr] Data última revisão:
161128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131107
[St] Status:MEDLINE
[do] DOI:10.1289/ehp.1306648



página 1 de 36 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde