Base de dados : MEDLINE
Pesquisa : D02.522.352.110 [Categoria DeCS]
Referências encontradas : 153 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 16 ir para página                         

  1 / 153 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28281770
[Au] Autor:De Lange SS; Fuller A; Haw A; Hofmeyr M; Buss P; Miller M; Meyer LC
[Ti] Título:Tremors in white rhinoceroses (Ceratotherium simum) during etorphine-azaperone immobilisation.
[So] Source:J S Afr Vet Assoc;88(0):e1-e10, 2017 Feb 24.
[Is] ISSN:2224-9435
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:Little is known about the mechanisms causing tremors during immobilisation of rhinoceros and whether cardiorespiratory supportive interventions alter their intensity. Therefore, we set out to determine the possible mechanisms that lead to muscle tremors and ascertain whether cardiorespiratory supportive interventions affect tremor intensity. We studied tremors and physiological responses during etorphine-azaperone immobilisation in eight boma-held and 14 free-living white rhinoceroses. Repeated measures analysis of variance and a Friedman test were used to determine differences in variables over time and between interventions. Spearman and Pearson correlations were used to test for associations between variables. Tremor intensity measured objectively by activity loggers correlated well (p < 0.0001; r2 = 0.9) with visual observations. Tremor intensity was greatest when animals were severely hypoxaemic and acidaemic. Tremor intensity correlated strongly and negatively with partial pressure of oxygen (PaO2 ) (p = 0.0003; r2 = 0.9995) and potential of hydrogen (pH) (p = 0.02, r2 = 0.97). It correlated strongly and positively with adrenaline concentrations (p = 0.003; r2 = 0.96), and adrenaline correlated strongly and negatively with PaO2 (p = 0.03; r2 = 0.95) and pH (p = 0.03; r2 = 0.94). Therefore, hypoxaemia and acidaemia were likely associated with the intensity of tremors through their activation of the release of tremorgenic levels of adrenaline. Tremors can be reduced if circulating adrenaline is reduced, and this can be achieved by the administration of butorphanol plus oxygen insufflation. Furthermore, to assist with reducing the risks associated with rhinoceros immobilisation, tremor intensity could be used as a clinical indicator of respiratory and metabolic compromise.
[Mh] Termos MeSH primário: Azaperona/efeitos adversos
Etorfina/efeitos adversos
Hipnóticos e Sedativos/efeitos adversos
Hipóxia/veterinária
Perissodáctilos
Tremor/veterinária
[Mh] Termos MeSH secundário: Análise de Variância
Animais
Butorfanol/uso terapêutico
Epinefrina/sangue
Hipóxia/induzido quimicamente
Hipóxia/fisiopatologia
Imobilização/métodos
Imobilização/veterinária
Masculino
Monitorização Fisiológica
Antagonistas de Entorpecentes/uso terapêutico
Perissodáctilos/sangue
Perissodáctilos/fisiologia
Distribuição Aleatória
África do Sul
Tremor/induzido quimicamente
Tremor/tratamento farmacológico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Hypnotics and Sedatives); 0 (Narcotic Antagonists); 19BV78AK7W (Azaperone); 42M2Y6NU9O (Etorphine); QV897JC36D (Butorphanol); YKH834O4BH (Epinephrine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170311
[St] Status:MEDLINE
[do] DOI:10.4102/jsava.v88i0.1466


  2 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28155294
[Au] Autor:Fahlman Å; Edner A; Wenger S; Foggin C; Nyman G
[Ad] Endereço:Department of Clinical Sciences, Swedish University of Agricultural Sciences. asa_fahlman@hotmail.com.
[Ti] Título:Pulmonary gas exchange and acid-base status during immobilisation of black rhinoceroses (Diceros bicornis) in Zimbabwe.
[So] Source:J S Afr Vet Assoc;87(1):e1-e9, 2016 Dec 02.
[Is] ISSN:2224-9435
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:When immobilising wildlife, adverse side effects can include hypoxaemia, acidosis and hypertension. Pulmonary gas exchange and acid-base status were evaluated during immobilisation of 25 free-ranging and one boma-held black rhinoceros (Diceros bicornis) in Zimbabwe. The effect of different body positions on arterial oxygenation was evaluated. A combination of the following drugs was used: an opioid (etorphine or thiafentanil), azaperone and an a2 -adrenoceptor agonist (detomidine or xylazine). Respiratory and heart rates, rectal temperature and pulse oximetry-derived haemoglobin oxygen saturation were recorded. Serial arterial blood samples were analysed immediately in the field. Marked hypoxaemia and hypercapnia were recorded in immobilised free-ranging black rhinoceroses. Arterial oxygenation was higher during sternal compared to lateral recumbency. Most rhinoceroses developed acidaemia of respiratory and metabolic origin. Initially high lactate concentrations in free-ranging rhinoceroses decreased during immobilisation. Pulse oximetry was unreliable in the detection of hypoxaemia. Positioning in sternal recumbency and routine use of oxygen supplementation are recommended in the management of immobilised rhinoceroses as measures to improve arterial oxygenation.
[Mh] Termos MeSH primário: Equilíbrio Ácido-Base
Imobilização/veterinária
Perissodáctilos/fisiologia
Troca Gasosa Pulmonar
[Mh] Termos MeSH secundário: Agonistas de Receptores Adrenérgicos alfa 2/administração & dosagem
Analgésicos Opioides/administração & dosagem
Animais
Animais Selvagens
Azaperona/administração & dosagem
Antagonistas de Dopamina/administração & dosagem
Etorfina/administração & dosagem
Feminino
Fentanila/administração & dosagem
Fentanila/análogos & derivados
Imidazóis/administração & dosagem
Imobilização/métodos
Masculino
Xilazina/administração & dosagem
Zimbábue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (A3080); 0 (Adrenergic alpha-2 Receptor Agonists); 0 (Analgesics, Opioid); 0 (Dopamine Antagonists); 0 (Imidazoles); 19BV78AK7W (Azaperone); 2KFG9TP5V8 (Xylazine); 42M2Y6NU9O (Etorphine); 7N8K34P2XH (detomidine); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170224
[Lr] Data última revisão:
170224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170204
[St] Status:MEDLINE
[do] DOI:10.4102/jsava.v87i1.1328


  3 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28080912
[Au] Autor:Watson MK; Thurber M; Chinnadurai SK
[Ti] Título:COMPARISON OF MEDETOMIDINE-KETAMINE AND BUTORPHANOL-AZAPERONE-MEDETOMIDINE IN CAPTIVE BENNETT'S WALLABIES (MACROPUS RUFOGRISEUS).
[So] Source:J Zoo Wildl Med;47(4):1019-1024, 2016 Dec.
[Is] ISSN:1042-7260
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The objective of this study was to compare a traditional partially reversible medetomidine-ketamine sedation with a more reversible butorphanol-azaperone-medetomidine combination in Bennett's wallabies ( Macropus rufogriseus ) maintained in a zoological collection. Fourteen animals were divided into two treatment groups. Individuals in group 1 received an intramuscular (i.m.) injection of butorphanol (0.54 ± 0.05 mg/kg), azaperone (0.22 ± 0.02 mg/kg), and medetomidine (0.16 ± 0.02 mg/kg). Individuals in group 2 received an i.m. injection of ketamine (5.43 ±1.16 mg/kg) with medetomidine (0.05 ± 0.014 mg/kg). For group 1, sedation was reversed with atipamezole (0.81 ± 0.069 mg/kg i.m.) and naltrexone (1.08 ± 0.09 mg/kg i.m.). For group 2, sedation was reversed with atipamezole (0.27 ± 0.056 mg/kg i.m.). There were no significant differences between the groups in mean time to induction, time spent on gas anesthesia, or time to standing after reversal was administered. Animals in both groups required supplemental gas anesthesia to facilitate intubation. No adverse reactions or effects were noted with either protocol; however, the BAM protocol did not provide sufficient sedation for handling in all animals and may not be suitable for use in this species.
[Mh] Termos MeSH primário: Azaperona/farmacologia
Butorfanol/farmacologia
Ketamina/farmacologia
Marsupiais
Medetomidina/farmacologia
[Mh] Termos MeSH secundário: Antagonistas de Receptores Adrenérgicos alfa 2/administração & dosagem
Antagonistas de Receptores Adrenérgicos alfa 2/farmacologia
Analgésicos Opioides/administração & dosagem
Analgésicos Opioides/farmacologia
Anestésicos Dissociativos/administração & dosagem
Anestésicos Dissociativos/farmacologia
Animais
Animais de Zoológico
Azaperona/administração & dosagem
Butorfanol/administração & dosagem
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/farmacologia
Imidazóis/administração & dosagem
Imidazóis/farmacologia
Ketamina/administração & dosagem
Medetomidina/administração & dosagem
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adrenergic alpha-2 Receptor Antagonists); 0 (Analgesics, Opioid); 0 (Anesthetics, Dissociative); 0 (Hypnotics and Sedatives); 0 (Imidazoles); 03N9U5JAF6 (atipamezole); 19BV78AK7W (Azaperone); 690G0D6V8H (Ketamine); MR15E85MQM (Medetomidine); QV897JC36D (Butorphanol)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170309
[Lr] Data última revisão:
170309
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170113
[St] Status:MEDLINE
[do] DOI:10.1638/2015-0190.1


  4 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28046175
[Au] Autor:Das G; Vernunft A; Görs S; Kanitz E; Weitzel JM; Brüssow KP; Metges CC
[Ti] Título:Acute effects of general anesthesia with propofol, pentobarbital or isoflurane plus propofol on plasma metabolites and hormones in adult pigs.
[So] Source:J Anim Sci;94(12):5182-5191, 2016 Dec.
[Is] ISSN:1525-3163
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Experimental setups for physiological research, in which acute operative interventions need to be performed, can require inclusion of general anesthesia (GA), which may interfere or confound with the effects of the experimental factors of interest on measured variables. It was recently shown that the most commonly used sedatives/anesthetics in pigs (e.g., ketamine, xylazine, azaperone) affect physiological responses and thus the primary metabolic readouts have the potential to be confounded. To extend the search for a physiologically-friendly anesthesia regime for such studies, we investigated effects of GA induced by propofol (Prop) or pentobarbital (Pent) or propofol plus isoflurane (Prop + Isof) on plasma concentrations of commonly measured metabolites and hormones. In 2 experimental runs, 6 female pigs fitted with jugular vein catheters were used. Fasted pigs received either no drug (CON) or anesthetized rotationally either with Prop, Pent or Prop + Isof on different days, separated with washout periods of sufficient length (2 to 3 d). Six-h profiles of glucose, lactate, non-esterified fatty acids (NEFA), triglycerides (TG), cholesterol, urea as well as hormones including glucagon, insulin and cortisol were determined. Concentrations of cholesterol, urea and glucagon remained unaffected by any of the treatments ( > 0.05). Pent tended to increase cortisol from 30 to 90 min after drug administration. Glucose and lactate concentrations were increased ( < 0.05) by Prop and Pent within the first hour of GA ( < 0.05). Propofol and Pent reduced NEFA concentrations, which were more pronounced during the last 2 h of the studied period. Triglyceride concentrations were increased by all 3 agents within the first 45 min with Prop containing treatments exerting a stronger effect than Pent. Our data suggest that GA with Prop and particularly with Pent adulterate plasma metabolite and hormone profiles of pigs acutely, and thus has the potential to confound the effects of experimental factors of interest. Although Prop + Isof anesthesia did not differ from the controls, providing a physiologically-friendly GA, both single and the isoflurane-combined treatment of Prop induced hypertriglyceridemia due to the lipid adjuvant of the Prop drugs. It is concluded that readouts obtained under GA may be influenced both by physiological adulterations as response to anesthesia as well as by artifacts due to accompanying ingredients of the drug formulations.
[Mh] Termos MeSH primário: Anestesia Geral/veterinária
Anestésicos/farmacologia
Hipnóticos e Sedativos/farmacologia
Suínos/metabolismo
[Mh] Termos MeSH secundário: Animais
Azaperona/farmacologia
Glicemia/análise
Glicemia/efeitos dos fármacos
Feminino
Hidrocortisona/sangue
Insulina/sangue
Isoflurano/farmacologia
Ketamina/farmacologia
Pentobarbital/farmacologia
Propofol/farmacologia
Suínos/sangue
Xilazina/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics); 0 (Blood Glucose); 0 (Hypnotics and Sedatives); 0 (Insulin); 19BV78AK7W (Azaperone); 2KFG9TP5V8 (Xylazine); 690G0D6V8H (Ketamine); CYS9AKD70P (Isoflurane); I4744080IR (Pentobarbital); WI4X0X7BPJ (Hydrocortisone); YI7VU623SF (Propofol)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170104
[St] Status:MEDLINE
[do] DOI:10.2527/jas.2016-1018


  5 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27695801
[Au] Autor:Das G; Vernunft A; Görs S; Kanitz E; Weitzel JM; Brüssow KP; Metges CC
[Ti] Título:Effects of general anesthesia with ketamine in combination with the neuroleptic sedatives xylazine or azaperone on plasma metabolites and hormones in pigs.
[So] Source:J Anim Sci;94(8):3229-3239, 2016 Aug.
[Is] ISSN:1525-3163
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Physiological research with swine often includes sedation or general anesthesia (GA), which may influence the basal physiological responses of experimental animals and may have the potential to confound or interfere with the effects of experimental factors of interest. Using 6 adult female pigs, we investigated whether selected plasma metabolites and hormones are influenced by GA induced with ketamine (K) and 2 neuroleptic sedatives, namely azaperone (A) and xylazine (X). Fasted pigs rotationally received either no drug, a single intravenous administration of A or X, or A or X combined with ketamine (AK or XK, respectively), and plasma concentrations of glucose, lactate, non-esterified fatty acids (NEFA), triglycerides (TG), glucagon, insulin, and cortisol were determined for a 5-h period following administration. Azaperone and X induced deep sedation, whereas AK and XK induced GA. Overall, the average plasma glucose concentrations were increased by A and X, with the latter exerting a stronger effect that was also associated with hypoinsulinemia ( < 0.05). Time-dependent effects indicated a more rapid increase in glucose concentration due to X or XK than AK. Plasma NEFA concentrations were elevated by A and AK and to a lesser extent by X and XK ( < 0.05). Plasma lactate and TG levels were elevated by A and AK and remained unaffected by X or XK. Plasma cortisol concentrations were elevated ( < 0.05) by X and XK and even more so with a single administration of A ( < 0.05), while the combined effect of A with ketamine resulted in the highest cortisol concentrations ( < 0.05). Our data suggest that the effects of azaperone are mediated by cortisol but less so for xylazine, which also indicates that azaperone elicits a stronger stress response in pigs. Xylazine probably induces long-lasting, fasting-state hyperglycemia through the stimulation of hepatic glucose production associated with hypoinsulinemia. A discriminant analysis based on the variation in all of the measured metabolites and hormones, collectively, indicated that ketamine induced no additional effect on the overall physiological response patterns than that of the individual sedatives. In conclusion, the neuroleptic sedatives azaperone, and to a lesser extent, xylazine, acutely affect the metabolism of pigs, so primary metabolic readouts obtained under these drugs may be confounded.
[Mh] Termos MeSH primário: Azaperona/farmacologia
Ketamina/farmacologia
Suínos
Xilazina/farmacologia
[Mh] Termos MeSH secundário: Anestesia Geral/veterinária
Anestésicos Dissociativos/administração & dosagem
Anestésicos Dissociativos/farmacologia
Animais
Azaperona/administração & dosagem
Estudos Cross-Over
Quimioterapia Combinada
Feminino
Hidrocortisona/sangue
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/farmacologia
Insulina/sangue
Ketamina/administração & dosagem
Xilazina/administração & dosagem
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics, Dissociative); 0 (Hypnotics and Sedatives); 0 (Insulin); 19BV78AK7W (Azaperone); 2KFG9TP5V8 (Xylazine); 690G0D6V8H (Ketamine); WI4X0X7BPJ (Hydrocortisone)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE


  6 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:27691950
[Au] Autor:Buss P; Miller M; Fuller A; Haw A; Wanty R; Olea-Popelka F; Meyer L
[Ti] Título:CARDIOVASCULAR EFFECTS OF ETORPHINE, AZAPERONE, AND BUTORPHANOL COMBINATIONS IN CHEMICALLY IMMOBILIZED CAPTIVE WHITE RHINOCEROS (CERATOTHERIUM SIMUM).
[So] Source:J Zoo Wildl Med;47(3):834-843, 2016 Sep.
[Is] ISSN:1042-7260
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chemical capture is an essential tool in the management and conservation of white rhinoceros ( Ceratotherium simum ); however, cardiovascular responses in immobilized megaherbivores are poorly understood. Blood pressure and heart rate responses in rhinoceros immobilized with etorphine or etorphine plus azaperone, and the effects of subsequent i.v. butorphanol administration were investigated. Six white rhinoceros were used in a randomized crossover study design with four interventions: 1) etorphine i.m.; 2) etorphine plus azaperone i.m.; 3) etorphine i.m. and butorphanol i.v.; and 4) etorphine plus azaperone i.m., and butorphanol i.v. Etorphine resulted in hypertension and tachycardia in immobilized rhinoceros on initial measurements. Over the 25-min study period, blood pressures and heart rate declined. Heart rates were slower, although the rhinoceros were still tachycardic, and blood pressures lower during the whole study period in animals immobilized with etorphine and azaperone compared with those that received only etorphine. Butorphanol administration resulted in lower arterial blood pressures and heart rates in etorphine-immobilized rhinoceros. In rhinoceros immobilized with etorphine and azaperone, heart rate slowed following administration of butorphanol i.v., although blood pressures remained unchanged. Azaperone reduced hypertension associated with etorphine immobilization, but animals remained tachycardic. Administration of butorphanol to etorphine/azaperone-immoblized rhinoceros lowered heart rate to values approaching normal resting levels without altering blood pressure.
[Mh] Termos MeSH primário: Azaperona/farmacologia
Pressão Sanguínea/efeitos dos fármacos
Butorfanol/farmacologia
Etorfina/farmacologia
Frequência Cardíaca/efeitos dos fármacos
Perissodáctilos
[Mh] Termos MeSH secundário: Analgésicos Opioides/administração & dosagem
Analgésicos Opioides/farmacologia
Animais
Azaperona/administração & dosagem
Butorfanol/administração & dosagem
Estudos Cross-Over
Quimioterapia Combinada
Etorfina/administração & dosagem
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/farmacologia
Masculino
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Analgesics, Opioid); 0 (Hypnotics and Sedatives); 19BV78AK7W (Azaperone); 42M2Y6NU9O (Etorphine); QV897JC36D (Butorphanol)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170107
[Lr] Data última revisão:
170107
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE


  7 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27010262
[Au] Autor:Pon K; Caulkett N; Woodbury M
[Ti] Título:EFFICACY AND SAFETY OF A MEDETOMIDINE-AZAPERONE-ALFAXALONE COMBINATION IN CAPTIVE WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS).
[So] Source:J Zoo Wildl Med;47(1):29-37, 2016 Mar.
[Is] ISSN:1042-7260
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Alfaxalone is a neurosteroid that interacts with gamma-aminobutyric type A receptors to produce central nervous system depression and muscle relaxation. The effects of alfaxalone vary from sedation to general anesthesia. Alfaxalone is synergistic with other tranquilizers and sedatives and therefore has the potential to improve existing alpha-2 adrenergic agonist-based combinations used for wildlife immobilization. The objective of this study was to determine the efficacy and cardiopulmonary effects of a medetomidine-azaperone-alfaxalone (MAA) combination in captive white-tailed deer (Odocoileus virginianus). Eight captive white-tailed deer were restrained in a drop-floor chute; hand injected i.m. with 0.15 mg/kg medetomidine, 0.2 mg/kg azaperone, and 0.5 mg/kg alfaxalone; and released into a small enclosure for observation. The deer were maintained in lateral recumbency for a total time from postinjection (PI) of the drug of 60 min. At 60 min PI, atipamezole was administered i.m. at five times the medetomidine dose. Heart rate, respiratory rate, rectal temperature, and direct systolic, mean, and diastolic arterial blood pressures were recorded every 5 min. Arterial blood samples were taken every 15 min for blood gas analysis. Level of sedation and quality of recovery were scored. Statistical analysis was performed using analysis of variance and descriptive statistics with a significance level of P < 0.05. Induction (time to lateral recumbency, 7.1 ± 2.4 min (mean ± SD) and recovery times (time to standing, 9.1 ± 3.1 min) were comparable to currently used medetomidine-based combinations in white-tailed deer. Major cardiopulmonary effects observed (values reported are 15 min PI of immobilizing drugs) were hypoxemia (PaO2, 54 ± 9 mm Hg), hypoventilation (PaCO2, 55 ± 3 mm Hg), and mixed acid-base disturbances (pH, 7.22 ± 0.04). No adverse effects were observed after recovery from anesthesia. MAA produced a satisfactory level of deep sedation for safe handling and minor procedures in captive white-tailed deer.
[Mh] Termos MeSH primário: Azaperona/farmacologia
Cervos
Medetomidina/farmacologia
Pregnanodionas/farmacologia
[Mh] Termos MeSH secundário: Anestésicos/administração & dosagem
Anestésicos/farmacologia
Criação de Animais Domésticos
Animais
Azaperona/administração & dosagem
Pressão Sanguínea/efeitos dos fármacos
Temperatura Corporal/efeitos dos fármacos
Combinação de Medicamentos
Feminino
Frequência Cardíaca/efeitos dos fármacos
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/farmacologia
Medetomidina/administração & dosagem
Pregnanodionas/administração & dosagem
Respiração/efeitos dos fármacos
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anesthetics); 0 (Drug Combinations); 0 (Hypnotics and Sedatives); 0 (Pregnanediones); 19BV78AK7W (Azaperone); BD07M97B2A (alphaxalone); MR15E85MQM (Medetomidine)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:160325
[Lr] Data última revisão:
160325
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160325
[St] Status:MEDLINE
[do] DOI:10.1638/2015-0121.1


  8 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26967141
[Au] Autor:Lian M; Beckmen KB; Bentzen TW; Demma DJ; Arnemo JM
[Ad] Endereço:1 Department of Forestry and Wildlife Management, Faculty of Applied Ecology and Agricultural Sciences, Hedmark University College, Campus Evenstad, NO-2480 Elverum, Norway.
[Ti] Título:THIAFENTANIL-AZAPERONE-XYLAZINE AND CARFENTANIL-XYLAZINE IMMOBILIZATIONS OF FREE-RANGING CARIBOU (RANGIFER TARANDUS GRANTI) IN ALASKA, USA.
[So] Source:J Wildl Dis;52(2):327-34, 2016 04 28.
[Is] ISSN:1943-3700
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Carfentanil-xylazine (CX) has been the primary drug combination used for immobilizing free-ranging ungulates in Alaska, US since 1986. We investigated the efficacy of a potential new drug of choice, thiafentanil (Investigational New Animal Drug A-3080). Captive trials indicated that thiafentanil-azaperone-medetomidine could provide good levels of immobilization. However, field trials conducted in October 2013 on free-ranging caribou ( Rangifer tarandus granti) calves showed the combination too potent, causing three respiratory arrests and one mortality. The protocol was revised to thiafentanil-azaperone-xylazine (TAX), with good results. The induction time was not significantly different between the two combinations. However, the recovery time was significantly shorter for the TAX group than for the CX group. A physiologic evaluation was performed on 12 animals immobilized on CX and 15 animals on TAX. Arterial blood was collected after induction and again after 10 min of intranasal oxygen supplements (1 L/min). Both groups had significant increases in partial pressure of arterial oxygen after oxygen treatment. There was a concurrent significant increase in partial pressure of arterial carbon dioxide in both groups. Rectal temperature increased significantly in both groups during the downtime, which is consistent with other studies of potent opioids in ungulates. On the basis of our results, we found TAX to be a potential alternative for the current CX protocol for immobilizing free-ranging caribou calves via helicopter darting.
[Mh] Termos MeSH primário: Azaperona/farmacologia
Fentanila/análogos & derivados
Imobilização/veterinária
Rena
Xilazina/farmacologia
[Mh] Termos MeSH secundário: Alaska
Analgésicos Opioides/administração & dosagem
Analgésicos Opioides/farmacologia
Animais
Azaperona/administração & dosagem
Quimioterapia Combinada
Feminino
Fentanila/administração & dosagem
Fentanila/farmacologia
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/farmacologia
Xilazina/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (A3080); 0 (Analgesics, Opioid); 0 (Hypnotics and Sedatives); 19BV78AK7W (Azaperone); 2KFG9TP5V8 (Xylazine); LA9DTA2L8F (carfentanil); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160312
[St] Status:MEDLINE
[do] DOI:10.7589/2015-04-101


  9 / 153 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26845295
[Au] Autor:Wolfe LL; Miller MW
[Ad] Endereço:1 Colorado Division of Parks and Wildlife, Wildlife Health Program, 4330 Laporte Avenue, Fort Collins, Colorado 80521-2153, USA.
[Ti] Título:USING TAILORED TRANQUILIZER COMBINATIONS TO REDUCE STRESS ASSOCIATED WITH LARGE UNGULATE CAPTURE AND TRANSLOCATION.
[So] Source:J Wildl Dis;52(2 Suppl):S118-24, 2016 Apr.
[Is] ISSN:1943-3700
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Capture and translocation are important tools for managing and studying large ungulates. Although widely used, many established field practices cause fear and stress in subject animals that can hamper overall effectiveness and safety. Over the last 10 years we have been exploring uses of tranquilizer combinations as adjuncts to wild ungulate capture and translocation work in Colorado, USA. Our approaches have been tailored to various field applications to reduce fear and stress, facilitate handling, and improve the overall success of capture and translocation for research or management purposes. For physical capture (drop net or helicopter-net gunning) with local release, combinations of midazolam and azaperone administered immediately upon capture provide transient tranquilization and muscle relaxation during manual restraint and handling to prevent hyperthermia and capture myopathy. For extended tranquilization (during transport and overnight holding), adding a sustained-release haloperidol formulation provides calming effects for at least 24-48 h. In our assessment, appropriate and adaptive use of these tranquilizer combinations benefits captured animals without impeding management or research goals.
[Mh] Termos MeSH primário: Cervos
Doenças dos Ovinos/prevenção & controle
Carneiro da Montanha
Estresse Fisiológico/efeitos dos fármacos
Estresse Psicológico/prevenção & controle
Tranquilizantes/administração & dosagem
[Mh] Termos MeSH secundário: Animais
Azaperona/administração & dosagem
Colorado
Preparações de Ação Retardada
Combinação de Medicamentos
Feminino
Haloperidol/administração & dosagem
Masculino
Midazolam/administração & dosagem
Ovinos
Estresse Psicológico/etiologia
Transportes
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Delayed-Action Preparations); 0 (Drug Combinations); 0 (Tranquilizing Agents); 19BV78AK7W (Azaperone); J6292F8L3D (Haloperidol); R60L0SM5BC (Midazolam)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160205
[St] Status:MEDLINE
[do] DOI:10.7589/52.2S.S118


  10 / 153 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:26304140
[Au] Autor:Haw A; Hofmeyr M; Fuller A; Buss P; Miller M; Fleming G; Meyer L
[Ad] Endereço:School of Physiology, Faculty of Health Sciences, University of the Witwatersrand. Anna.Haw@wits.ac.za.
[Ti] Título:Butorphanol with oxygen insufflation improves cardiorespiratory function in field-immobilised white rhinoceros (Ceratotherium simum).
[So] Source:J S Afr Vet Assoc;86(1):E1-E10, 2015 Aug 12.
[Is] ISSN:2224-9435
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:Opioid-induced immobilisation results in severe respiratory compromise in the white rhinoceros (Ceratotherium simum). The effectiveness of oxygen insufflation combined with butorphanol in alleviating respiratory depression in free-ranging chemically immobilised white rhinoceroses was investigated. In this prospective intervention study 14 free-ranging white rhinoceroses were immobilised with a combination of etorphine, azaperone and hyaluronidase. Six minutes (min) after the animals became recumbent, intravenous butorphanol was administered and oxygen insufflation was initiated. Previous boma trial results were used for comparison, using repeated measures two-way analysis of variance. The initial immobilisation-induced hypoxaemia in free-ranging rhinoceroses (arterial partial pressure of oxygen [PaO2] 35.4 mmHg ± 6.6 mmHg) was similar to that observed in boma-confined rhinoceroses (PaO2 31 mmHg ± 6 mmHg, n = 8). Although the initial hypercapnia (PaCO2 63.0 mmHg ± 7.5 mmHg) was not as severe as that in animals in the boma trial (79 mmHg ± 7 mmHg), the field-immobilised rhinoceroses were more acidaemic (pH 7.10 ± 0.14) at the beginning of the immobilisation compared with boma-immobilised rhinoceroses (pH 7.28 ± 0.04). Compared with pre-intervention values, butorphanol with oxygen insufflation improved the PaO2 (81.2 mmHg ± 23.7 mmHg, p < 0.001, 5 min vs 20 min), arterial partial pressure of carbon dioxide (55.3 mmHg ± 5.2 mmHg, p < 0.01, 5 min vs 20 min), pH (7.17 ± 0.11, p < 0.001, 5 min vs 20 min), heart rate (78 breaths/min ± 20 breaths/min, p < 0.001, 5 min vs 20 min) and mean arterial blood pressure (105 mmHg ± 14 mmHg, p < 0.01, 5 min vs 20 min). Oxygen insufflation combined with a single intravenous dose of butorphanol improved oxygenation and reduced hypercapnia and acidaemia in immobilised free-ranging white rhinoceroses.
[Mh] Termos MeSH primário: Butorfanol/uso terapêutico
Hipóxia/veterinária
Insuflação/veterinária
Oxigênio/farmacologia
Perissodáctilos/fisiologia
Testes de Função Respiratória/veterinária
[Mh] Termos MeSH secundário: Animais
Azaperona/administração & dosagem
Azaperona/efeitos adversos
Butorfanol/administração & dosagem
Dióxido de Carbono/sangue
Etorfina/administração & dosagem
Etorfina/efeitos adversos
Hialuronoglucosaminidase/administração & dosagem
Hialuronoglucosaminidase/efeitos adversos
Hipnóticos e Sedativos/administração & dosagem
Hipnóticos e Sedativos/efeitos adversos
Hipóxia/induzido quimicamente
Hipóxia/tratamento farmacológico
Imobilização/veterinária
Masculino
Oxigênio/administração & dosagem
Oxigênio/sangue
Estudos Prospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Hypnotics and Sedatives); 142M471B3J (Carbon Dioxide); 19BV78AK7W (Azaperone); 42M2Y6NU9O (Etorphine); EC 3.2.1.35 (Hyaluronoglucosaminidase); QV897JC36D (Butorphanol); S88TT14065 (Oxygen)
[Em] Mês de entrada:1604
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150826
[St] Status:MEDLINE
[do] DOI:10.4102/jsava.v86i1.1276



página 1 de 16 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde