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[PMID]:29251978
[Au] Autor:Moore BA; Buono FD; Printz DMB; Lloyd DP; Fiellin DA; Cutter CJ; Schottenfeld RS; Barry DT
[Ad] Endereço:Department of Psychiatry, Yale University School of Medicine.
[Ti] Título:Customized recommendations and reminder text messages for automated, computer-based treatment during methadone.
[So] Source:Exp Clin Psychopharmacol;25(6):485-495, 2017 12.
[Is] ISSN:1936-2293
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Recovery Line is an automated, computer-based intervention based on cognitive behavioral therapy (CBT) designed to provide real-time assistance by phone for patients in methadone maintenance. Preliminary efficacy findings were promising, however, as with other computer-based systems for substance use disorder, patient system use was less than recommended. Development and evaluation of system functions to increase patient engagement and use is needed. Thus, we conducted two randomized trials to evaluate system functions designed to increase patient use of the Recovery Line among methadone-maintained patients with continued illicit drug use. In Trial 1 (n = 60), patients received customized, system use recommendations or no recommendations on each Recovery Line call. Ratings of system usability were higher for customized recommendations (CR), but number of calls and total call time did not differ by condition. Trial 2 evaluated characteristics of reminder messages (message frame and reminder latency). Participants (N = 67) received gain- and loss-frame reminder messages, and were randomly assigned to immediate, short, or long term message latency. Although message framing had no effect, gender interacted with latency condition such that females did not differ by message latency, while males had significantly greater total contact time in the short latency conditions. Number of calls differed by condition over time such that the shorter latencies led to greater calls initially, but dissipated over time. Overall the study indicates that computer-based self-management systems can be adapted to increase patient engagement and use. (PsycINFO Database Record
[Mh] Termos MeSH primário: Analgésicos Opioides/uso terapêutico
Metadona/uso terapêutico
Tratamento de Substituição de Opiáceos
Transtornos Relacionados ao Uso de Opioides/terapia
Mensagem de Texto/utilização
Terapia Assistida por Computador/métodos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Transtornos Relacionados ao Uso de Opioides/psicologia
Tempo de Reação
Sistemas de Alerta
Estudos Retrospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Analgesics, Opioid); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180224
[Lr] Data última revisão:
180224
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171219
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1037/pha0000149


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[PMID]:29346444
[Au] Autor:Tran BX; Nguyen LH; Tran TT; Latkin CA
[Ad] Endereço:Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
[Ti] Título:Social and structural barriers for adherence to methadone maintenance treatment among Vietnamese opioid dependence patients.
[So] Source:PLoS One;13(1):e0190941, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Methadone maintenance treatment (MMT) services may reduce the risk of HIV transmission if patients completely adhere to the treatment. Identifying adherence patterns and potential related factors is vital for the sustainability of MMT program in Vietnam. This study examined social and structural factors associated with adherence to MMT among patients in different service delivery models. MATERIALS AND METHODS: A total of 510 patients at three MMT clinics in Hanoi were interviewed. Measures of self-reported adherence included the number of missed doses in the past 7 days and the level of adherence in the past 30 days using a visual analog scale (VAS) scoring from 0 (non-adherence) to 100 (perfect adherence). Multivariate regressions were employed to identify factors associated with non-adherence to MMT. RESULTS: A total of 17.7% of participants reported incomplete MMT adherence in the last 30 days and 8.3% reported missing a dose in the last seven days, respectively. Living with HIV/AIDS, poor self-care and usual activities, and disclosure of health issues to spouses or intimate partners were associated with non-adherence. Those patients with pain or depression were more likely to report better adherence. Disclosing health status to spouse/partner increased the risk of incomplete adherence, while disclosing to friends reduced the number of missed dose in the last seven days. Patients attending clinics with comprehensive services had a lower VAS score of adherence compared to those enrolling in clinics with only MMT and general health care. CONCLUSIONS: Sustaining the compliance of patients to MMT is principal in the rapid expansion of this service in Vietnam. It is necessary to address the complexity of health care demands of drug users, their difficulties to be rehabilitated into workforce and society, and the stigmatization to maximize the outcomes of MMT program.
[Mh] Termos MeSH primário: Metadona/administração & dosagem
Tratamento de Substituição de Opiáceos
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Cooperação do Paciente
Comportamento Social
[Mh] Termos MeSH secundário: Adulto
Estudos Transversais
Feminino
Seres Humanos
Masculino
Transtornos Relacionados ao Uso de Opioides/psicologia
Estigma Social
Vietnã
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180119
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190941


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[PMID]:27770695
[Au] Autor:Carrieri P; Vilotitch A; Nordmann S; Lions C; Michel L; Mora M; Morel A; Maradan G; Spire B; Roux P; Methaville Study Group
[Ad] Endereço:INSERM U912 (SESSTIM), Marseille, France; Université Aix Marseille, IRD, UMR-S912, Marseille, France; ORS PACA, Observatoire Régional de la Santé Provence Alpes Côte d'Azur, Marseille, France.
[Ti] Título:Decrease in self-reported offences and incarceration rates during methadone treatment: A comparison between patients switching from buprenorphine to methadone and maintenance treatment incident users (ANRS-Methaville trial).
[So] Source:Int J Drug Policy;39:86-91, 2017 01.
[Is] ISSN:1873-4758
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Patients receiving buprenorphine who are poor responders can continue to commit drug-related offences. Switching them from buprenorphine to methadone may result in reduced criminal behaviour. We compared self-reported offences and incarceration before and after starting methadone treatment of patients switching from buprenorphine (PSB) and maintenance treatment incident users (MIU). METHODS: Data on offences, incarceration and other information, were obtained via a telephone interview. Mixed models were used to assess the impact of methadone initiation and being PSB or MIU on (1) the number of days when offences were committed (drug sale, drug purchase, other offences) and (2) experiencing incarceration during the previous 6 months. RESULTS: Among the 176 patients with at least one assessment for self-reported offences, 51.7% were PSB. Receiving methadone was significantly associated with a reduction in the number of days when drug sale or drug purchase offences were committed, but not other offences. PSB and MIU groups were different only for drug purchase, as PSB were more likely to have a higher number of days of drug purchase from month 3 onwards. A reduction of 77% in the likelihood of experiencing incarceration was observed and this was comparable in PSB and MIU. CONCLUSION: Switching non-responding buprenorphine patients to methadone can result in a major reduction in offences and incarceration rates. Increasing access to methadone, using more flexible models of care is urgent for clinical and public health reasons.
[Mh] Termos MeSH primário: Buprenorfina/efeitos adversos
Crime/estatística & dados numéricos
Metadona/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Tráfico de Drogas/estatística & dados numéricos
Feminino
França
Seres Humanos
Masculino
Tratamento de Substituição de Opiáceos/estatística & dados numéricos
Ensaios Clínicos Controlados Aleatórios como Assunto/estatística & dados numéricos
Autorrelato
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
40D3SCR4GZ (Buprenorphine); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE


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[PMID]:28450464
[Au] Autor:Luo X; Gong X; Zhao P; Zou X; Chen W; Ling L
[Ad] Endereço:Faculty of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen Center for Migrant Health Policy, Sun Yat-Sen University, Guangzhou, China.
[Ti] Título:Positive percentages of urine morphine tests among methadone maintenance treatment clients with HIV/AIDS: a 12-month follow-up study in Guangdong Province, China.
[So] Source:BMJ Open;7(4):e014237, 2017 04 27.
[Is] ISSN:2044-6055
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: We aimed to assess the positive percentages of urine morphine tests and correlates among methadone maintenance treatment (MMT) clients with HIV/AIDS in Guangdong, China. SETTING: Fourteen MMT clinics located in nine cities of Guangdong were chosen as study sites. PARTICIPANTS: In this study, we reviewed 293 clients with opioid dependence, who were HIV seropositive, 18 years or older, provided informed consent and had at least 10 records of urine morphine tests during the study period. PRIMARY AND SECONDARY OUTCOME MEASURES: The positive percentages of urine morphine tests were calculated and underlying predictors were estimated. RESULTS: The highest positive percentage (95.9%) was observed in the first month. After excluding the highest percentage in the first month, the average positive percentage was 40.9% for month 2 to month 12. Positive percentages of urine morphine tests that were <20%, 20-60% and >80% were 25.4%, 36.1% and 38.5% respectively. Lower percentages of continued heroin use were associated with being young (OR =0.31, 95% CI 0.12 to 0.78; OR =0.44, 95% CI 0.20 to 1.00), and financial sources depending on family or friends (OR=0.55, 95% CI 0.32 to 0.93). Higher percentages of continued heroin use were associated with being unemployed (OR=1.99, 95% CI 1.13 to 3.49) and poor MMT attendance (OR =3.60, 95% CI 1.55 to 8.33; OR =2.80, 95% CI 1.48 to 5.33). CONCLUSIONS: High positive percentages of urine morphine tests remain prevalent among MMT clients with HIV/AIDS in Guangdong. The present findings have implications for taking effective measures to facilitate attendance in order to decrease heroin use and ultimately improve the effectiveness among these sub-group MMT clients.
[Mh] Termos MeSH primário: Síndrome de Imunodeficiência Adquirida/tratamento farmacológico
Metadona/uso terapêutico
Derivados da Morfina/urina
Transtornos Relacionados ao Uso de Opioides/diagnóstico
[Mh] Termos MeSH secundário: Adulto
China/epidemiologia
Feminino
Seguimentos
Seres Humanos
Masculino
Transtornos Relacionados ao Uso de Opioides/epidemiologia
Prevalência
Assunção de Riscos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Morphine Derivatives); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180201
[Lr] Data última revisão:
180201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1136/bmjopen-2016-014237


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[PMID]:28458076
[Au] Autor:Ding Z; Chen Y; Wang X; Zhou X; Xu Y; Ma Z; Sun Y; Jiang M
[Ad] Endereço:Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui, PR China; Department of Automation, University of Science and Technology of China, Hefei, Anhui, PR China.
[Ti] Título:A comparison of bone quality and its determinants in young opioid-dependent women with healthy control group.
[So] Source:Drug Alcohol Depend;175:232-236, 2017 06 01.
[Is] ISSN:1879-0046
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Little is known about bone quality and its determinants in patients with opioid addiction. The goal of this study was to compare bone quality and its determinants in young opioid addicted women with a local group of young healthy women. METHOD: Using cross-sectional design, 104 women (mean age 29.9 yrs, range: 20-40 yrs, SD=7.8) with previous opioid addiction and current methadone substitution (3-30mg, daily) for 1-16 weeks were compared to 117 healthy women (mean age 31.0 yrs, range: 20-40 yrs, SD=5.9). Bone quality was examined with quantitative ultrasound. Anthropometric characteristics (body weight, fat free mass (FFM), fat mass) were obtained by bioelectrical impedance analysis. Substance use and other risk factors for low bone quality were assessed by questionnaire-based interviews. RESULTS: More than one-quarter (34%) of patients had osteopenia (n=31) or osteoporosis (n=4), compared to 16% of the healthy control group having osteopenia (n=18). Bivariate correlation analysis demonstrated that age, body weight, and FFM correlated with bone quality (p<0.05) in healthy women, which were not found in patients. Multivariate analyses showed that in healthy controls, the determinants of bone quality were age, body height, physical activity, and BMI, but in patients, the determinant of bone quality was duration of drug intake. CONCLUSIONS: Long-term opioid dependence in young women may lead to low bone quality. Efforts to increase awareness of low bone quality in young opioid addicted women should be considered so that effective treatment may be employed to lower future fracture risk.
[Mh] Termos MeSH primário: Doenças Ósseas Metabólicas/induzido quimicamente
Osso e Ossos/efeitos dos fármacos
Transtornos Relacionados ao Uso de Opioides/fisiopatologia
Osteoporose/induzido quimicamente
[Mh] Termos MeSH secundário: Adulto
Analgésicos Opioides/uso terapêutico
Composição Corporal/efeitos dos fármacos
Estatura/efeitos dos fármacos
Índice de Massa Corporal
Peso Corporal/efeitos dos fármacos
Estudos de Casos e Controles
Estudos Transversais
Exercício
Feminino
Seres Humanos
Metadona/uso terapêutico
Transtornos Relacionados ao Uso de Opioides/complicações
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Analgesics, Opioid); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


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[PMID]:29190831
[Au] Autor:Lugoboni F; Zamboni L; Federico A; Tamburin S; Gruppo InterSERT di Collaborazione Scientifica (GICS)
[Ad] Endereço:Department of Medicine, Addiction Medicine Unit, Verona University Hospital, Verona, Italy.
[Ti] Título:Erectile dysfunction and quality of life in men receiving methadone or buprenorphine maintenance treatment. A cross-sectional multicentre study.
[So] Source:PLoS One;12(11):e0188994, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Erectile dysfunction (ED) is common among men on opioid replacement therapy (ORT), but most previous studies exploring its prevalence and determinants yielded contrasting findings. Moreover, the impact of ED on patients' quality of life (QoL) has been seldom explored. OBJECTIVE: To explore the prevalence and determinants of ED in men on ORT, and the impact on QoL. METHODS: In a multicentre cross-sectional study, we recruited 797 consecutive male patients on methadone and buprenorphine treatment, collected data on demographic, clinical, and psychopathological factors, and explored their role as predictors of ED and QoL through univariate and multivariate analysis. ED severity was assessed with a self-assessment questionnaire. RESULTS: Nearly half of patients in our sample were sexually inactive or reported some degree of ED. Some demographic, clinical and psychopathological variables significantly differed according to the presence or absence of ED. Multivariate regression analysis indicated that age, employment, smoke, psychoactive drugs, opioid maintenance dosage, and severity of psychopathological factors significantly influenced the risk and severity of ED. QoL was worse in patients with ED and significantly correlated with ED severity. Age, education, employment, opioid maintenance dosage, ED score, and severity of psychopathology significantly influenced QoL in the multivariate analysis. CONCLUSIONS: ED complaints can be explored in male opioid users on ORT through a simple and quick self-assessment tool. ED may have important effects on emotional and social well-being, and may affect outcome.
[Mh] Termos MeSH primário: Buprenorfina/administração & dosagem
Disfunção Erétil
Metadona/administração & dosagem
Tratamento de Substituição de Opiáceos/efeitos adversos
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Qualidade de Vida
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos Transversais
Seres Humanos
Masculino
Meia-Idade
Transtornos Relacionados ao Uso de Opioides/fisiopatologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY
[Nm] Nome de substância:
40D3SCR4GZ (Buprenorphine); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180101
[Lr] Data última revisão:
180101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188994


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[PMID]:27773585
[Au] Autor:Ruan X; Luo JJ; Kaye AD
[Ad] Endereço:Dept. of Anesthesiology, Louisiana State University Health Science Center, 1542 Tulane Ave, New Orleans, LA, 70112, USA. Electronic address: drxruan88@gmail.com.
[Ti] Título:Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
[So] Source:Eur J Cancer;68:199-200, 2016 11.
[Is] ISSN:1879-0852
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Fentanila
Metadona
[Mh] Termos MeSH secundário: Analgésicos Opioides
Neoplasias de Cabeça e Pescoço
Seres Humanos
Neoplasias
Neuralgia
Dor
Medição da Dor
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Analgesics, Opioid); UC6VBE7V1Z (Methadone); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180101
[Lr] Data última revisão:
180101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:27771240
[Au] Autor:Haumann J; Geurts JW; van Kuijk SM; Kremer B; Joosten EA; van den Beuken-van Everdingen MH
[Ad] Endereço:University Pain Centre Maastricht (UPCM), Department of Anesthesiology and Pain Management, Maastricht University Medical Centre, Maastricht, The Netherlands; Department of Anaesthesiology and Pain Management, OLVG, Amsterdam, The Netherlands.
[Ti] Título:Letter response: Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
[So] Source:Eur J Cancer;68:201-202, 2016 11.
[Is] ISSN:1879-0852
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Fentanila
Metadona
[Mh] Termos MeSH secundário: Analgésicos Opioides
Neoplasias de Cabeça e Pescoço
Seres Humanos
Neuralgia
Dor
Medição da Dor
[Pt] Tipo de publicação:LETTER; COMMENT
[Nm] Nome de substância:
0 (Analgesics, Opioid); UC6VBE7V1Z (Methadone); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180101
[Lr] Data última revisão:
180101
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29040331
[Au] Autor:Lagisetty P; Klasa K; Bush C; Heisler M; Chopra V; Bohnert A
[Ad] Endereço:Division of General Internal Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America.
[Ti] Título:Primary care models for treating opioid use disorders: What actually works? A systematic review.
[So] Source:PLoS One;12(10):e0186315, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Primary care-based models for Medication-Assisted Treatment (MAT) have been shown to reduce mortality for Opioid Use Disorder (OUD) and have equivalent efficacy to MAT in specialty substance treatment facilities. OBJECTIVE: The objective of this study is to systematically analyze current evidence-based, primary care OUD MAT interventions and identify program structures and processes associated with improved patient outcomes in order to guide future policy and implementation in primary care settings. DATA SOURCES: PubMed, EMBASE, CINAHL, and PsychInfo. METHODS: We included randomized controlled or quasi experimental trials and observational studies evaluating OUD treatment in primary care settings treating adult patient populations and assessed structural domains using an established systems engineering framework. RESULTS: We included 35 interventions (10 RCTs and 25 quasi-experimental interventions) that all tested MAT, buprenorphine or methadone, in primary care settings across 8 countries. Most included interventions used joint multi-disciplinary (specialty addiction services combined with primary care) and coordinated care by physician and non-physician provider delivery models to provide MAT. Despite large variability in reported patient outcomes, processes, and tasks/tools used, similar key design factors arose among successful programs including integrated clinical teams with support staff who were often advanced practice clinicians (nurses and pharmacists) as clinical care managers, incorporating patient "agreements," and using home inductions to make treatment more convenient for patients and providers. CONCLUSIONS: The findings suggest that multidisciplinary and coordinated care delivery models are an effective strategy to implement OUD treatment and increase MAT access in primary care, but research directly comparing specific structures and processes of care models is still needed.
[Mh] Termos MeSH primário: Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Atenção Primária à Saúde
[Mh] Termos MeSH secundário: Adulto
Buprenorfina/uso terapêutico
Assistência à Saúde
Seres Humanos
Metadona/uso terapêutico
Transtornos Relacionados ao Uso de Opioides/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
40D3SCR4GZ (Buprenorphine); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171018
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186315


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[PMID]:28953686
[Au] Autor:Zhang HS; Xu YM; Zhu JH; Zhong BL
[Ad] Endereço:Department of Psychiatry, Affiliated Wuhan Mental Health Center (The Ninth Clinical School), Tongji Medical College of Huazhong University of Science & Technology, Wuhan, Hubei Province, China.
[Ti] Título:Poor sleep quality is significantly associated with low sexual satisfaction in Chinese methadone-maintained patients.
[So] Source:Medicine (Baltimore);96(39):e8214, 2017 Sep.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sleep disturbance negatively affects sexual function. Sleep problem and sexual dysfunction are common in methadone-maintained patients; however, their association is understudied in this patient population.This study examined the association between sleep quality and sexual satisfaction in Chinese patients receiving methadone maintenance treatment (MMT).This was a cross-sectional study. A total of 480 MMT patients who had sex with their sex partners within 1 month before the survey were recruited from 3 MMT clinics in Wuhan, China. Sexual satisfaction was assessed with a single question, and sociodemographic and clinical data were collected with a standardized questionnaire. Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Multiple ordinary logistic regression was used to control for potential confounders that may bias the sleep-sexual satisfaction relationship.Sexual satisfaction scores were significantly higher in poor sleepers than normal sleepers (3.2 ±â€Š0.9 vs. 2.8 ±â€Š1.0, t = 4.297, P < .001). After controlling for potential confounders, results of the multiple regression analysis reveal that poor sleep quality was still significantly and independently associated with low sexual satisfaction (odd ratio = 1.58, P = .009).Poor sleep quality is significantly associated with low sexual satisfaction of methadone-maintained patients. Improving sleep quality might improve sexual satisfaction of patients receiving MMT.
[Mh] Termos MeSH primário: Metadona/uso terapêutico
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Orgasmo/fisiologia
Qualidade de Vida
Distúrbios do Início e da Manutenção do Sono
[Mh] Termos MeSH secundário: Adulto
China
Feminino
Seres Humanos
Masculino
Meia-Idade
Entorpecentes/uso terapêutico
Tratamento de Substituição de Opiáceos/efeitos adversos
Tratamento de Substituição de Opiáceos/métodos
Tratamento de Substituição de Opiáceos/psicologia
Transtornos Relacionados ao Uso de Opioides/psicologia
Distúrbios do Início e da Manutenção do Sono/complicações
Distúrbios do Início e da Manutenção do Sono/psicologia
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Narcotics); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008214



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