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  1 / 1066 MEDLINE  
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[PMID]:28407573
[Au] Autor:Janowska B; Szymanski K; Sidelko R; Siebielska I; Walendzik B
[Ad] Endereço:Koszalin University of Technology, Faculty of Civil Engineering, Environmental and Geodetic Sciences, Department of Waste Management, ul. Sniadeckich, 75-453 Koszalin, Poland. Electronic address: beata.janowska@tu.koszalin.pl.
[Ti] Título:Assessment of mobility and bioavailability of mercury compounds in sewage sludge and composts.
[So] Source:Environ Res;156:394-403, 2017 07.
[Is] ISSN:1096-0953
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Content of heavy metals, including mercury, determines the method of management and disposal of sewage sludge. Excessive concentration of mercury in composts used as organic fertilizer may lead to accumulation of this element in soil and plant material. Fractionation of mercury in sewage sludge and composts provides a better understanding of the extent of mobility and bioavailability of the different mercury species and helps in more informed decision making on the application of sludge for agricultural purposes. The experimental setup comprises the composing process of the sewage sludge containing 13.1mgkg of the total mercury, performed in static reactors with forced aeration. In order to evaluate the bioavailability of mercury, its fractionation was performed in sewage sludge and composts during the process. An analytical procedure based on four-stage sequential extraction was applied to determine the mercury content in the ion exchange (water soluble and exchangeable Hg), base soluble (Hg bound to humic and fulvic acid), acid soluble (Hg bound to Fe/Mn oxides and carbonates) and oxidizable (Hg bound to organic matter and sulphide) fractions. The results showed that from 50.09% to 64.55% of the total mercury was strongly bound to organo-sulphur and inorganic sulphide; that during composting, increase of concentrations of mercury compounds strongly bound with organic matter and sulphides; and that mercury content in the base soluble and oxidizable fractions was strongly correlated with concentration of dissolved organic carbon in those fractions.
[Mh] Termos MeSH primário: Compostos Organomercúricos/análise
Compostos Organomercúricos/metabolismo
Esgotos/química
Poluentes do Solo/análise
Poluentes do Solo/metabolismo
Solo/química
[Mh] Termos MeSH secundário: Disponibilidade Biológica
Madeira/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Organomercury Compounds); 0 (Sewage); 0 (Soil); 0 (Soil Pollutants)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171119
[Lr] Data última revisão:
171119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170414
[St] Status:MEDLINE


  2 / 1066 MEDLINE  
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[PMID]:28339347
[Au] Autor:Bridges CC; Zalups RK
[Ad] Endereço:a Mercer University School of Medicine , Division of Basic Medical Sciences , Macon , Georgia , USA.
[Ti] Título:The aging kidney and the nephrotoxic effects of mercury.
[So] Source:J Toxicol Environ Health B Crit Rev;20(2):55-80, 2017.
[Is] ISSN:1521-6950
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Owing to advances in modern medicine, life expectancies are lengthening and leading to an increase in the population of older individuals. The aging process leads to significant alterations in many organ systems, with the kidney being particularly susceptible to age-related changes. Within the kidney, aging leads to ultrastructural changes such as glomerular and tubular hypertrophy, glomerulosclerosis, and tubulointerstitial fibrosis, which may compromise renal plasma flow (RPF) and glomerular filtration rate (GFR). These alterations may reduce the functional reserve of the kidneys, making them more susceptible to pathological events when challenged or stressed, such as following exposure to nephrotoxicants. An important and prevalent environmental toxicant that induces nephrotoxic effects is mercury (Hg). Since exposure of normal kidneys to mercuric ions might induce glomerular and tubular injury, aged kidneys, which may not be functioning at full capacity, may be more sensitive to the effects of Hg than normal kidneys. Age-related renal changes and the effects of Hg in the kidney have been characterized separately. However, little is known regarding the influence of nephrotoxicants, such as Hg, on aged kidneys. The purpose of this review was to summarize known findings related to exposure of aged and diseased kidneys to the environmentally relevant nephrotoxicant Hg.
[Mh] Termos MeSH primário: Envelhecimento
Poluentes Ambientais/toxicidade
Rim/efeitos dos fármacos
Compostos de Mercúrio/toxicidade
Mercúrio/toxicidade
Compostos Organomercúricos/toxicidade
[Mh] Termos MeSH secundário: Animais
Seres Humanos
Rim/fisiologia
Rim/fisiopatologia
Nefropatias/induzido quimicamente
Camundongos
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Mercury Compounds); 0 (Organomercury Compounds); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170325
[St] Status:MEDLINE
[do] DOI:10.1080/10937404.2016.1243501


  3 / 1066 MEDLINE  
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[PMID]:27422290
[Au] Autor:Bridges CC; Zalups RK
[Ad] Endereço:Division of Basic Medical Sciences, Mercer University School of Medicine, 1550 College Street, Macon, GA, 31207, USA. bridges_cc@mercer.edu.
[Ti] Título:Mechanisms involved in the transport of mercuric ions in target tissues.
[So] Source:Arch Toxicol;91(1):63-81, 2017 Jan.
[Is] ISSN:1432-0738
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Mercury exists in the environment in various forms, all of which pose a risk to human health. Despite guidelines regulating the industrial release of mercury into the environment, humans continue to be exposed regularly to various forms of this metal via inhalation or ingestion. Following exposure, mercuric ions are taken up by and accumulate in numerous organs, including brain, intestine, kidney, liver, and placenta. In order to understand the toxicological effects of exposure to mercury, a thorough understanding of the mechanisms that facilitate entry of mercuric ions into target cells must first be obtained. A number of mechanisms for the transport of mercuric ions into target cells and organs have been proposed in recent years. However, the ability of these mechanisms to transport mercuric ions and the regulatory features of these carriers have not been characterized completely. The purpose of this review is to summarize the current findings related to the mechanisms that may be involved in the transport of inorganic and organic forms of mercury in target tissues and organs. This review will describe mechanisms known to be involved in the transport of mercury and will also propose additional mechanisms that may potentially be involved in the transport of mercuric ions into target cells.
[Mh] Termos MeSH primário: Poluentes Ambientais/toxicidade
Compostos de Mercúrio/toxicidade
Modelos Biológicos
Compostos Organomercúricos/toxicidade
[Mh] Termos MeSH secundário: Absorção Fisiológica
Animais
Transporte Biológico
Barreira Hematoencefálica
Poluentes Ambientais/metabolismo
Feminino
Seres Humanos
Masculino
Troca Materno-Fetal
Compostos de Mercúrio/metabolismo
Intoxicação por Mercúrio/embriologia
Intoxicação por Mercúrio/metabolismo
Compostos de Metilmercúrio/metabolismo
Compostos de Metilmercúrio/toxicidade
Compostos Organomercúricos/metabolismo
Gravidez
Distribuição Tecidual
Toxicocinética
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Mercury Compounds); 0 (Methylmercury Compounds); 0 (Organomercury Compounds)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160717
[St] Status:MEDLINE
[do] DOI:10.1007/s00204-016-1803-y


  4 / 1066 MEDLINE  
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[PMID]:26820485
[Au] Autor:Wahba HM; Lecoq L; Stevenson M; Mansour A; Cappadocia L; Lafrance-Vanasse J; Wilkinson KJ; Sygusch J; Wilcox DE; Omichinski JG
[Ad] Endereço:Faculty of Pharmacy, Beni-suef University , Beni-suef, Egypt.
[Ti] Título:Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
[So] Source:Biochemistry;55(7):1070-81, 2016 Feb 23.
[Is] ISSN:1520-4995
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In bacterial resistance to mercury, the organomercurial lyase (MerB) plays a key role in the detoxification pathway through its ability to cleave Hg-carbon bonds. Two cysteines (C96 and C159; Escherichia coli MerB numbering) and an aspartic acid (D99) have been identified as the key catalytic residues, and these three residues are conserved in all but four known MerB variants, where the aspartic acid is replaced with a serine. To understand the role of the active site serine, we characterized the structure and metal binding properties of an E. coli MerB mutant with a serine substituted for D99 (MerB D99S) as well as one of the native MerB variants containing a serine residue in the active site (Bacillus megaterium MerB2). Surprisingly, the MerB D99S protein copurified with a bound metal that was determined to be Cu(II) from UV-vis absorption, inductively coupled plasma mass spectrometry, nuclear magnetic resonance, and electron paramagnetic resonance studies. X-ray structural studies revealed that the Cu(II) is bound to the active site cysteine residues of MerB D99S, but that it is displaced following the addition of either an organomercurial substrate or an ionic mercury product. In contrast, the B. megaterium MerB2 protein does not copurify with copper, but the structure of the B. megaterium MerB2-Hg complex is highly similar to the structure of the MerB D99S-Hg complexes. These results demonstrate that the active site aspartic acid is crucial for both the enzymatic activity and metal binding specificity of MerB proteins and suggest a possible functional relationship between MerB and its only known structural homologue, the copper-binding protein NosL.
[Mh] Termos MeSH primário: Ácido Aspártico/metabolismo
Cobre/metabolismo
Proteínas de Escherichia coli/química
Liases/química
Modelos Moleculares
Proteínas Mutantes/química
Compostos Organomercúricos/metabolismo
[Mh] Termos MeSH secundário: Substituição de Aminoácidos
Ácido Aspártico/química
Bacillus megaterium/enzimologia
Proteínas de Bactérias/química
Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Biocatálise
Domínio Catalítico
Cobre/química
Cristalografia por Raios X
Escherichia coli/enzimologia
Proteínas de Escherichia coli/genética
Proteínas de Escherichia coli/metabolismo
Liases/genética
Liases/metabolismo
Mercúrio/química
Mercúrio/metabolismo
Mutagênese Sítio-Dirigida
Proteínas Mutantes/genética
Proteínas Mutantes/metabolismo
Compostos Organomercúricos/química
Conformação Proteica
Proteínas Recombinantes/química
Proteínas Recombinantes/metabolismo
Serina/química
Serina/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Escherichia coli Proteins); 0 (Mutant Proteins); 0 (Organomercury Compounds); 0 (Recombinant Proteins); 30KYC7MIAI (Aspartic Acid); 452VLY9402 (Serine); 789U1901C5 (Copper); EC 4.- (Lyases); EC 4.99.1.2 (MerB protein, Bacteria); EC 4.99.1.2 (alkylmercury lyase); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160223
[Lr] Data última revisão:
160223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160129
[St] Status:MEDLINE
[do] DOI:10.1021/acs.biochem.5b01298


  5 / 1066 MEDLINE  
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[PMID]:26498643
[Au] Autor:LaVoie SP; Mapolelo DT; Cowart DM; Polacco BJ; Johnson MK; Scott RA; Miller SM; Summers AO
[Ad] Endereço:Department of Microbiology, University of Georgia, Athens, GA, 30602, USA.
[Ti] Título:Organic and inorganic mercurials have distinct effects on cellular thiols, metal homeostasis, and Fe-binding proteins in Escherichia coli.
[So] Source:J Biol Inorg Chem;20(8):1239-51, 2015 Dec.
[Is] ISSN:1432-1327
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The protean chemical properties of the toxic metal mercury (Hg) have made it attractive in diverse applications since antiquity. However, growing public concern has led to an international agreement to decrease its impact on health and the environment. During a recent proteomics study of acute Hg exposure in E. coli, we also examined the effects of inorganic and organic Hg compounds on thiol and metal homeostases. On brief exposure, lower concentrations of divalent inorganic mercury Hg(II) blocked bulk cellular thiols and protein-associated thiols more completely than higher concentrations of monovalent organomercurials, phenylmercuric acetate (PMA) and merthiolate (MT). Cells bound Hg(II) and PMA in excess of their available thiol ligands; X-ray absorption spectroscopy indicated nitrogens as likely additional ligands. The mercurials released protein-bound iron (Fe) more effectively than common organic oxidants and all disturbed the Na(+)/K(+) electrolyte balance, but none provoked efflux of six essential transition metals including Fe. PMA and MT made stable cysteine monothiol adducts in many Fe-binding proteins, but stable Hg(II) adducts were only seen in CysXxx(n)Cys peptides. We conclude that on acute exposure: (a) the distinct effects of mercurials on thiol and Fe homeostases reflected their different uptake and valences; (b) their similar effects on essential metal and electrolyte homeostases reflected the energy dependence of these processes; and (c) peptide phenylmercury-adducts were more stable or detectable in mass spectrometry than Hg(II)-adducts. These first in vivo observations in a well-defined model organism reveal differences upon acute exposure to inorganic and organic mercurials that may underlie their distinct toxicology.
[Mh] Termos MeSH primário: Escherichia coli/efeitos dos fármacos
Homeostase/efeitos dos fármacos
Proteínas de Ligação ao Ferro/metabolismo
Mercúrio/farmacologia
Mercúrio/toxicidade
[Mh] Termos MeSH secundário: Espectroscopia de Ressonância de Spin Eletrônica
Poluentes Ambientais/toxicidade
Compostos Organomercúricos/toxicidade
Compostos de Sulfidrila
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Iron-Binding Proteins); 0 (Organomercury Compounds); 0 (Sulfhydryl Compounds); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151027
[St] Status:MEDLINE
[do] DOI:10.1007/s00775-015-1303-1


  6 / 1066 MEDLINE  
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[PMID]:26432029
[Au] Autor:Teraoka H; Okamoto E; Kudo M; Nakayama SM; Ikenaka Y; Ishizuka M; Endo T; Kitazawa T; Hiraga T
[Ad] Endereço:School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu 069-8501, Japan. Electronic address: hteraoka@rakuno.ac.jp.
[Ti] Título:Accumulation properties of inorganic mercury and organic mercury in the red-crowned crane Grus japonensis in east Hokkaido, Japan.
[So] Source:Ecotoxicol Environ Saf;122:557-64, 2015 Dec.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The red-crowned (Japanese) crane Grus japonensis is native to east Hokkaido, Japan, in contrast to the East Asia mainland. Previously, we reported that red-crowned cranes in Hokkaido were highly contaminated with mercury in the 1990s and that the contamination rapidly decreased to a moderate level in the 2000s. In the present study, we determined levels of organic mercury (O-Hg) in the liver and kidney of cranes in east Hokkaido in comparison with levels of total mercury (T-Hg). T-Hg levels in the kidneys were higher than those in the livers in adults but not in subadults and juveniles; however, the reverse was the case for O-Hg even for adults. The ratio of O-Hg to T-Hg in both the liver and kidney decreased as T-Hg increased in the three developmental stages. While the ratios of O-Hg to T-Hg in the liver and kidney of adults were significantly lower than those of juveniles, the ratios were similar for adults and juveniles in a lower range of T-Hg. The ratio of selenium (Se) to T-Hg decreased as T-Hg increased in both the liver and kidney, irrespective of stages. Mercury burdens in feathers were about 59% and 67% of the total body burdens for juveniles and adults, respectively. Furthermore, ratios of carbon and nitrogen stable isotopes to T-Hg varied greatly, with no relation to mercury level in the liver. The results suggest slow accumulation of inorganic mercury in the kidney of red-crowned cranes in east Hokkaido, Japan.
[Mh] Termos MeSH primário: Envelhecimento/metabolismo
Aves/metabolismo
Poluentes Ambientais/farmacocinética
Mercúrio/farmacocinética
Compostos Organomercúricos/farmacocinética
[Mh] Termos MeSH secundário: Animais
Aves/crescimento & desenvolvimento
Carga Corporal (Radioterapia)
Poluentes Ambientais/análise
Plumas/química
Japão
Rim/química
Fígado/química
Mercúrio/análise
Compostos Organomercúricos/análise
Selênio/análise
Selênio/farmacocinética
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Organomercury Compounds); FXS1BY2PGL (Mercury); H6241UJ22B (Selenium)
[Em] Mês de entrada:1606
[Cu] Atualização por classe:151021
[Lr] Data última revisão:
151021
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151004
[St] Status:MEDLINE


  7 / 1066 MEDLINE  
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[PMID]:26363947
[Au] Autor:Li P; He M; Chen B; Hu B
[Ad] Endereço:Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
[Ti] Título:Automated dynamic hollow fiber liquid-liquid-liquid microextraction combined with capillary electrophoresis for speciation of mercury in biological and environmental samples.
[So] Source:J Chromatogr A;1415:48-56, 2015 Oct 09.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A simple home-made automatic dynamic hollow fiber based liquid-liquid-liquid microextraction (AD-HF-LLLME) device was designed and constructed for the simultaneous extraction of organomercury and inorganic mercury species with the assistant of a programmable flow injection analyzer. With 18-crown-6 as the complexing reagent, mercury species including methyl-, ethyl-, phenyl- and inorganic mercury were extracted into the organic phase (chlorobenzene), and then back-extracted into the acceptor phase of 0.1% (m/v) 3-mercapto-1-propanesulfonic acid (MPS) aqueous solution. Compared with automatic static (AS)-HF-LLLME system, the extraction equilibrium of target mercury species was obtained in shorter time with higher extraction efficiency in AD-HF-LLLME system. Based on it, a new method of AD-HF-LLLME coupled with large volume sample stacking (LVSS)-capillary electrophoresis (CE)/UV detection was developed for the simultaneous analysis of methyl-, phenyl- and inorganic mercury species in biological samples and environmental water. Under the optimized conditions, AD-HF-LLLME provided high enrichment factors (EFs) of 149-253-fold within relatively short extraction equilibrium time (25min) and good precision with RSD between 3.8 and 8.1%. By combining AD-HF-LLLME with LVSS-CE/UV, EFs were magnified up to 2195-fold and the limits of detection (at S/N=3) for target mercury species were improved to be sub ppb level.
[Mh] Termos MeSH primário: Compostos de Mercúrio/análise
Compostos Organomercúricos/análise
[Mh] Termos MeSH secundário: Animais
Quelantes/química
Éteres de Coroa/química
Cação (Peixe)
Eletroforese Capilar/métodos
Água Doce/análise
Cabelo/química
Seres Humanos
Microextração em Fase Líquida/métodos
Músculo Esquelético/química
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Chelating Agents); 0 (Crown Ethers); 0 (Mercury Compounds); 0 (Organomercury Compounds); 0 (Water Pollutants, Chemical); 63J177NC5B (18-crown-6)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:150924
[Lr] Data última revisão:
150924
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150914
[St] Status:MEDLINE


  8 / 1066 MEDLINE  
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[PMID]:25798600
[Au] Autor:Cheng B; Annamalai T; Sandhaus S; Bansod P; Tse-Dinh YC
[Ad] Endereço:Department of Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York, United States of America.
[Ti] Título:Inhibition of Zn(II) binding type IA topoisomerases by organomercury compounds and Hg(II).
[So] Source:PLoS One;10(3):e0120022, 2015.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Type IA topoisomerase activities are essential for resolving DNA topological barriers via an enzyme-mediated transient single strand DNA break. Accumulation of topoisomerase DNA cleavage product can lead to cell death or genomic rearrangement. Many antibacterial and anticancer drugs act as topoisomerase poison inhibitors that form stabilized ternary complexes with the topoisomerase covalent intermediate, so it is desirable to identify such inhibitors for type IA topoisomerases. Here we report that organomercury compounds were identified during a fluorescence based screening of the NIH diversity set of small molecules for topoisomerase inhibitors that can increase the DNA cleavage product of Yersinia pestis topoisomerase I. Inhibition of relaxation activity and accumulation of DNA cleavage product were confirmed for these organomercury compounds in gel based assays of Escherichia coli topoisomerase I. Hg(II), but not As(III), could also target the cysteines that form the multiple Zn(II) binding tetra-cysteine motifs found in the C-terminal domains of these bacterial topoisomerase I for relaxation activity inhibition. Mycobacterium tuberculosis topoisomerase I activity is not sensitive to Hg(II) or the organomercury compounds due to the absence of the Zn(II) binding cysteines. It is significant that the type IA topoisomerases with Zn(II) binding domains can still cleave DNA when interfered by Hg(II) or organomercury compounds. The Zn(II) binding domains found in human Top3α and Top3ß may be potential targets of toxic metals and organometallic complexes, with potential consequence on genomic stability and development.
[Mh] Termos MeSH primário: DNA Topoisomerases Tipo I/metabolismo
Mercúrio/farmacologia
Compostos Organomercúricos/farmacologia
Inibidores da Topoisomerase I/farmacologia
Zinco/metabolismo
[Mh] Termos MeSH secundário: Cisteína/metabolismo
DNA Topoisomerases Tipo I/química
Bases de Dados de Produtos Farmacêuticos
Avaliação Pré-Clínica de Medicamentos
Seres Humanos
Ligação Proteica
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Organomercury Compounds); 0 (Topoisomerase I Inhibitors); EC 5.99.1.2 (DNA Topoisomerases, Type I); FXS1BY2PGL (Mercury); J41CSQ7QDS (Zinc); K848JZ4886 (Cysteine)
[Em] Mês de entrada:1602
[Cu] Atualização por classe:161019
[Lr] Data última revisão:
161019
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150324
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0120022


  9 / 1066 MEDLINE  
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[PMID]:25629187
[Au] Autor:Nelson R
[Ti] Título:To eat fish or not to eat fish.
[So] Source:Am J Nurs;115(2):18-9, 2015 Feb.
[Is] ISSN:1538-7488
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Contaminação de Alimentos/estatística & dados numéricos
Preferências Alimentares
Compostos Organomercúricos/toxicidade
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Segurança de Produtos ao Consumidor
Dieta/estatística & dados numéricos
Peixes
Política de Saúde
Seres Humanos
Atum
Estados Unidos
United States Food and Drug Administration
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Organomercury Compounds); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1504
[Cu] Atualização por classe:150129
[Lr] Data última revisão:
150129
[Sb] Subgrupo de revista:AIM; IM; N
[Da] Data de entrada para processamento:150129
[St] Status:MEDLINE
[do] DOI:10.1097/01.NAJ.0000460681.97318.ad


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[PMID]:25577695
[Au] Autor:Deonarine A; Hsu-Kim H; Zhang T; Cai Y; Richardson CJ
[Ad] Endereço:Duke University, Department of Civil and Environmental Engineering, Box 90287, Durham, NC 27708, USA. Electronic address: amrikadeonarine@gmail.com.
[Ti] Título:Legacy source of mercury in an urban stream-wetland ecosystem in central North Carolina, USA.
[So] Source:Chemosphere;138:960-5, 2015 Nov.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In the United States, aquatic mercury contamination originates from point and non-point sources to watersheds. Here, we studied the contribution of mercury in urban runoff derived from historically contaminated soils and the subsequent production of methylmercury in a stream-wetland complex (Durham, North Carolina), the receiving water of this runoff. Our results demonstrated that the mercury originated from the leachate of grass-covered athletic fields. A fraction of mercury in this soil existed as phenylmercury, suggesting that mercurial anti-fungal compounds were historically applied to this soil. Further downstream in the anaerobic sediments of the stream-wetland complex, a fraction (up to 9%) of mercury was converted to methylmercury, the bioaccumulative form of the metal. Importantly, the concentrations of total mercury and methylmercury were reduced to background levels within the stream-wetland complex. Overall, this work provides an example of a legacy source of mercury that should be considered in urban watershed models and watershed management.
[Mh] Termos MeSH primário: Mercúrio/análise
Compostos Organomercúricos/análise
Rios/química
Poluentes do Solo/análise
Poluentes Químicos da Água/análise
Zonas Úmidas
[Mh] Termos MeSH secundário: Ecossistema
Modelos Teóricos
North Carolina
Solo/química
Urbanização
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Organomercury Compounds); 0 (Soil); 0 (Soil Pollutants); 0 (Water Pollutants, Chemical); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1605
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150112
[St] Status:MEDLINE



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