Base de dados : MEDLINE
Pesquisa : D02.691.750.100 [Categoria DeCS]
Referências encontradas : 42 [refinar]
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[PMID]:26643127
[Au] Autor:Chen Y; Cheng X; Mo F; Huang L; Wu Z; Wu Y; Xu L; Fu F
[Ad] Endereço:Key Laboratory of Analysis and Detection for Food Safety of Ministry of Education, Fujian Provincial Key Lab of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian, P. R. China.
[Ti] Título:Ultra-sensitive speciation analysis of mercury by CE-ICP-MS together with field-amplified sample stacking injection and dispersive solid-phase extraction.
[So] Source:Electrophoresis;37(7-8):1055-62, 2016 Apr.
[Is] ISSN:1522-2683
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:A simple dispersive solid-phase extraction (DSPE) used to extract and preconcentrate ultra-trace MeHg, EtHg and Hg(2+) from water sample, and a sensitive method for the simultaneous analysis of MeHg, EtHg and Hg(2+) by using capillary electrophoresis-inductively coupled plasma mass spectrometry (CE-ICP-MS) with field-amplified sample stacking injection (FASI) were first reported in this study. The DSPE used thiol cotton particles as adsorbent, and is simple and effective. It can be used to extract and preconcentrate ultra-trace mercury compounds in water samples within 30 min with a satisfied recovery and no mercury species alteration during the process. The FASI enhanced the sensitivity of CE-ICP-MS with 25-fold, 29-fold and 27-fold for MeHg, EtHg and Hg(2+) , respectively. Using FASI-CE-ICP-MS together with DSPE, we have successfully determined ultra-trace MeHg, EtHg and Hg(2+) in tap water with a limits of quantification (LOQs) of 0.26-0.45 pg/mL, an RSD (n = 3) < 6% and a recovery of 92-108%. Ultra-high sensitivity, as well as much less sample and reagent consumption and low operating cost, make our method a valuable technique to the speciation analysis of ultra-trace mercury.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/análise
Eletroforese Capilar/métodos
Espectrometria de Massas/métodos
Mercúrio/análise
Extração em Fase Sólida/métodos
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Compostos de Alquilmercúrio/química
Compostos de Alquilmercúrio/isolamento & purificação
Água Potável/química
Limite de Detecção
Modelos Lineares
Mercúrio/química
Mercúrio/isolamento & purificação
Reprodutibilidade dos Testes
Poluentes Químicos da Água/química
Poluentes Químicos da Água/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Drinking Water); 0 (Water Pollutants, Chemical); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151209
[St] Status:MEDLINE
[do] DOI:10.1002/elps.201500460


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[PMID]:24397750
[Au] Autor:Zhang Q; Yang G
[Ad] Endereço:a Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, College of Chemistry and Chemical Engineering , Ocean University of China , 238 Songling Road, Laoshan District, Qingdao 266100 , China.
[Ti] Título:Anatomical mercury speciation in bay scallops by thio-bearing chelating resin concentration and GC-electron capture detector determination.
[So] Source:Food Addit Contam Part A Chem Anal Control Expo Risk Assess;31(1):54-62, 2014.
[Is] ISSN:1944-0057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The highly toxic methyl-, ethyl- and phenylmercury species that may exist in the three main anatomical parts - the adductor muscle, the mantle and the visceral mass - of bay scallops (Argopecten irradias) were quantitatively released by cupric chloride, zinc acetate, sodium chloride and hydrochloric acid (HCl) under ultrasonic extraction. After centrifugation, the mercury species in the supernatant were concentrated by thio (SH)-bearing chelating resins, eluted with HClO4 and HCl and extracted with toluene. Separation was achieved by capillary GC equipped with programmed temperatures, a constant nitrogen flow and detected by a micro-electron capture detector (µECD). Under optimised conditions, the LODs for methyl-, ethyl- and phenylmercury in bay scallop samples were 1.1, 0.65 and 0.80 ng g(-1), respectively. The maximum RSD for three replicate determinations of methyl-, ethyl- and phenylmercury in bay scallop samples were 13.7%, 14.0% and 11.2%, respectively. In the concentration range of 4-200 ng g(-1) in bay scallop samples, the calibration graphs were linear with correlation coefficients not less than 0.997. Recoveries for spiked samples were in the range of 92.7-103.5% (methylmercury), 87.5-108.3% (ethylmercury) and 91.6-106.0% (phenylmercury), respectively. The method was verified by the determination of methylmercury in a CRM GBW10029 (Total Mercury and Methyl Mercury in Fish Tissue), with results in good agreement with the certified values. Methylmercury - the only existing species in bay scallops - was successfully determined by the method.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/análise
Compostos de Alquilmercúrio/toxicidade
Contaminação de Alimentos/análise
Pectinidae/química
Frutos do Mar/análise
Frutos do Mar/toxicidade
[Mh] Termos MeSH secundário: Animais
Aquicultura
Quelantes
Cromatografia Gasosa
Inocuidade dos Alimentos
Análise de Perigos e Pontos Críticos de Controle/métodos
Seres Humanos
Limite de Detecção
Intoxicação do Sistema Nervoso por Mercúrio/etiologia
Compostos de Metilmercúrio/análise
Compostos de Metilmercúrio/toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Chelating Agents); 0 (Methylmercury Compounds)
[Em] Mês de entrada:1409
[Cu] Atualização por classe:140121
[Lr] Data última revisão:
140121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140109
[St] Status:MEDLINE
[do] DOI:10.1080/19440049.2013.856037


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[PMID]:24016576
[Au] Autor:Chen X; Han C; Cheng H; Liu J; Xu Z; Yin X
[Ad] Endereço:Institute of Analytical and Applied Chemistry, Department of Chemistry, Zhejiang University, Hangzhou, 310027, China.
[Ti] Título:Determination of mercurial species in fish by inductively coupled plasma mass spectrometry with anion exchange chromatographic separation.
[So] Source:Anal Chim Acta;796:7-13, 2013 Sep 24.
[Is] ISSN:1873-4324
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This work demonstrated the feasibility of mercury speciation analysis by anion exchange chromatographic separation with inductively coupled plasma mass spectrometry detection. For the first time, by complexing with the mobile phase containing 3-mercapto-1-propanesulfonate into negatively charged complexes, fast separation of inorganic mercury (Hg(2+)), monomethylmercury (MeHg), ethylmercury (EtHg) and phenylmercury (PhHg) was achieved within 5 min on a 12.5-mm strong anion exchange column. The detection limits for Hg(2+), MeHg, EtHg and PhHg were 0.008, 0.024, 0.029 and 0.034 µg L(-1), respectively. The relative standard deviations of peak height and peak area (5.0 µg L(-1) for each Hg species) were all below 3%. The determined contents of Hg(2+), MeHg and total Hg in a certified reference material of fish tissue by the proposed method were in good accordance with the certified values with satisfactory recoveries. The relative errors for determining MeHg and total mercury were -2.4% and -1.2%, respectively, with an acceptable range for spike recoveries of 94-101%. Mercury speciation in 11 fish samples were then analyzed after the pretreated procedure. The mercury contents in all fish samples analyzed were found compliant with the criteria of the National Standards of China.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/análise
Cromatografia por Troca Iônica/métodos
Espectrometria de Massas/métodos
Mercúrio/análise
[Mh] Termos MeSH secundário: Animais
Ânions/química
Peixes
Limite de Detecção
Compostos de Sulfidrila/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (3-mercapto-1-propanesulfonate); 0 (Alkylmercury Compounds); 0 (Anions); 0 (Sulfhydryl Compounds); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1403
[Cu] Atualização por classe:130910
[Lr] Data última revisão:
130910
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130911
[St] Status:MEDLINE


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[PMID]:20877814
[Au] Autor:Aschner M; Onishchenko N; Ceccatelli S
[Ad] Endereço:Vanderbilt University School of Medicine, Department of Pediatrics, Pharmacology, and the Kennedy Center for Research on Human Development, Nashville, TN 37232, USA. michael.aschner@vanderbilt.edu
[Ti] Título:Toxicology of alkylmercury compounds.
[So] Source:Met Ions Life Sci;7:403-34, 2010.
[Is] ISSN:1559-0836
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Methylmercury is a global pollutant and potent neurotoxin whose abundance in the food chain mandates additional studies on the consequences and mechanisms of its toxicity to the central nervous system. Formulation of our new hypotheses was predicated on our appreciation for (a) the remarkable affinity of mercurials for the anionic form of sulfhydryl (-SH) groups, and (b) the essential role of thiols in protein biochemistry. The present chapter addresses pathways to human exposure of various mercury compounds, highlighting their neurotoxicity and potential involvement in neurotoxic injury and neurodegenerative changes, both in the developing and senescent brain. Mechanisms that trigger these effects are discussed in detail.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/análise
Exposição Ambiental/análise
Compostos de Mercúrio/análise
Doenças do Sistema Nervoso/metabolismo
[Mh] Termos MeSH secundário: Compostos de Alquilmercúrio/química
Exposição Ambiental/efeitos adversos
Seres Humanos
Compostos de Mercúrio/química
Intoxicação por Mercúrio/etiologia
Intoxicação por Mercúrio/metabolismo
Estrutura Molecular
Doenças do Sistema Nervoso/etiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; REVIEW
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Mercury Compounds)
[Em] Mês de entrada:1103
[Cu] Atualização por classe:100929
[Lr] Data última revisão:
100929
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100930
[St] Status:MEDLINE
[do] DOI:10.1039/BK9781847551771-00403


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[PMID]:20149921
[Au] Autor:Dórea JG
[Ti] Título:More on low-level non-occupational mercury exposure and health concerns.
[So] Source:Sci Total Environ;408(8):2008-9; author reply 2010, 2010 Mar 15.
[Is] ISSN:1879-1026
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/análise
Exposição Ambiental/análise
Mercúrio/análise
Saúde Pública
[Mh] Termos MeSH secundário: Compostos de Alquilmercúrio/toxicidade
Animais
Exposição Ambiental/efeitos adversos
Contaminação de Alimentos
Seres Humanos
Mercúrio/toxicidade
Sistema Nervoso/efeitos dos fármacos
Sistema Nervoso/metabolismo
Sistema Nervoso/patologia
Medição de Risco
[Pt] Tipo de publicação:COMMENT; LETTER
[Nm] Nome de substância:
0 (Alkylmercury Compounds); FXS1BY2PGL (Mercury)
[Em] Mês de entrada:1008
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100213
[St] Status:MEDLINE
[do] DOI:10.1016/j.scitotenv.2010.01.048


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[PMID]:20507113
[Au] Autor:Melnick JG; Yurkerwich K; Parkin G
[Ad] Endereço:Department of Chemistry, Columbia University, New York, New York 10027, USA.
[Ti] Título:Synthesis, structure, and reactivity of two-coordinate mercury alkyl compounds with sulfur ligands: relevance to mercury detoxification.
[So] Source:Inorg Chem;48(14):6763-72, 2009 Jul 20.
[Is] ISSN:1520-510X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The susceptibility of two-coordinate mercury alkyl compounds of the type X-Hg-R (where X is a monodentate sulfur donor) towards protolytic cleavage has been investigated as part of ongoing efforts to obtain information relevant to understanding the mechanism of action of the organomercurial lyase, MerB. Specifically, the reactivity of the two-coordinate mercury alkyl compounds PhSHgR, [mim(Bu(t))]HgR and {[Hmim(Bu(t))]HgR}(+) (Hmim(Bu(t)) = 2-mercapto-1-t-butylimidazole; R = Me, Et) towards PhSH was investigated, thereby demonstrating that the ability to cleave the Hg-C bond is very dependent on the nature of the system. For example, whereas the reaction of PhSHgMe with PhSH requires heating at 145 degrees C for several weeks to liberate CH(4), the analogous reaction of PhSHgEt with PhSH leads to evolution of C(2)H(6) over the course of 2 days at 100 degrees C. Furthermore, protolytic cleavage of the Hg-C bond by PhSH is promoted by Hmim(Bu(t)). For example, whereas the reaction of {[Hmim(Bu(t))]HgEt}(+) with PhSH eliminates C(2)H(6) at elevated temperatures, the protolytic cleavage occurs over a period of 2 days at room temperature in the presence of Hmim(Bu(t)). The ability of Hmim(Bu(t)) to promote the protolytic cleavage is interpreted in terms of the formation of a higher coordinate species {[Hmim(Bu(t))](n)HgR}(+) that is more susceptible to Hg-C bond cleavage than is two-coordinate {[Hmim(Bu(t))]HgR}(+). These observations support the notion that access to a species with a coordination number greater than two is essential for efficient activity of MerB.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/química
Compostos de Sulfidrila/química
Enxofre/química
[Mh] Termos MeSH secundário: Compostos de Alquilmercúrio/síntese química
Ligantes
Modelos Moleculares
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, U.S. GOV'T, NON-P.H.S.
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Ligands); 0 (Sulfhydryl Compounds); 70FD1KFU70 (Sulfur)
[Em] Mês de entrada:1009
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:100529
[St] Status:MEDLINE
[do] DOI:10.1021/ic900721g


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[PMID]:19491004
[Au] Autor:Dórea JG
[Ad] Endereço:Faculty of Health Sciences, Universidade de Brasilia, 70919-970 Brasilia, DF, Brazil. dorea@rudah.com.br
[Ti] Título:Risks of mercury exposure related to gestational fish consumption: beyond the sea.
[So] Source:Reprod Toxicol;28(1):113-4, 2009 Jul.
[Is] ISSN:1873-1708
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/efeitos adversos
Contaminação de Alimentos
Fenômenos Fisiológicos da Nutrição Pré-Natal
Alimentos Marinhos
Poluentes Químicos da Água/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Compostos de Alquilmercúrio/análise
Feminino
Feto/efeitos dos fármacos
Óleos de Peixe/administração & dosagem
Contaminação de Alimentos/análise
Idade Gestacional
Seres Humanos
Guias de Prática Clínica como Assunto
Gravidez
Medição de Risco
Alimentos Marinhos/análise
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Fish Oils); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:0907
[Cu] Atualização por classe:090603
[Lr] Data última revisão:
090603
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090604
[St] Status:MEDLINE
[do] DOI:10.1016/j.reprotox.2009.03.008


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[PMID]:19490835
[Au] Autor:Genuis SJ
[Ad] Endereço:University of Alberta, Faculty of Medicine, 2935-66 Street, Edmonton, Alberta, Canada T6K 4C1.
[Ti] Título:Nowhere to hide: Chemical toxicants and the unborn child.
[So] Source:Reprod Toxicol;28(1):115-6, 2009 Jul.
[Is] ISSN:1873-1708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Contemporary reproductive aged women and their offspring are facing an unprecedented onslaught of toxicant exposures from myriad sources in their day-to-day life. Public health recommendations regarding optimal diet and nutrition in pregnancy must incorporate several considerations including safety of available foodstuffs, cultural practices and lifestyle issues. Gestational consumption of contaminated seafood remains a potential source of toxicant exposure, including mercury, for the developing child. Health care professionals responsible for the care of women and their developing children need to become apprised of: a) risks associated with toxicant bioaccumulation in pregnancy; b) ongoing information emerging in the important field of reproductive toxicology; and c) strategies within the clinical setting to facilitate nutritional sufficiency and precautionary avoidance of adverse exposure among young women.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/efeitos adversos
Contaminação de Alimentos
Fenômenos Fisiológicos da Nutrição Pré-Natal
Alimentos Marinhos
Poluentes Químicos da Água/efeitos adversos
[Mh] Termos MeSH secundário: Adulto
Compostos de Alquilmercúrio/análise
Feminino
Feto/efeitos dos fármacos
Óleos de Peixe/administração & dosagem
Contaminação de Alimentos/análise
Idade Gestacional
Seres Humanos
Guias de Prática Clínica como Assunto
Gravidez
Medição de Risco
Alimentos Marinhos/análise
Poluentes Químicos da Água/análise
[Pt] Tipo de publicação:COMMENT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Fish Oils); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:0907
[Cu] Atualização por classe:090603
[Lr] Data última revisão:
090603
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:090604
[St] Status:MEDLINE
[do] DOI:10.1016/j.reprotox.2009.03.009


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[PMID]:18166986
[Au] Autor:Kakuschke A; Valentine-Thon E; Fonfara S; Griesel S; Rosenberger T; Siebert U; Prange A
[Ad] Endereço:GKSS Research Center, Institute for Coastal Research, Max-Planck-Strasse 1, 21502, Geesthacht, Germany. antje.kakuschke@gkss.de
[Ti] Título:Metal-induced impairment of the cellular immunity of newborn harbor seals (Phoca vitulina).
[So] Source:Arch Environ Contam Toxicol;55(1):129-36, 2008 Jul.
[Is] ISSN:1432-0703
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The cellular immunity of newborn harbor seals and the influence of pollutants are rarely investigated. This study evaluated the lymphocyte proliferation using a lymphocyte proliferation test (LTT) to understand the dynamics of immune response in seal pups of varying ages from the moment they arrived in a seal center after active beaching until their release into wildlife 3 months later after rehabilitation. Moreover, the effect of various metals (Ag, Al, Au, Be, Cd, Co, Cr, Cu, different Hg compounds, Mo, Ni, Pb, Pd, Pt, Sn, Ti) on lymphocyte proliferation in terms of immunosuppression and hypersensitivity was investigated. First, a strong lymphocyte proliferation in newborns as a reflection of relative immunocompetence was found. Second, different metal-induced influences on lymphocyte proliferation such as specific inhibition by Be, Cd, Hg, and Sn as well as stimulation induced by Mo and Ni were determined. For seals tested repeatedly, the suppressive effect was detected in newborns but not found in the same animals when they were older and had become immunologically competent. Summarizing, the lymphocyte proliferation used as a marker in this investigation provided useful immunological information on these developing animals, and its application for toxicological studies on pollutants can be recommended.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/toxicidade
Linfócitos/efeitos dos fármacos
Metais/toxicidade
Phoca/imunologia
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Animais Recém-Nascidos
Proliferação Celular/efeitos dos fármacos
Células Cultivadas
Imunidade Celular/efeitos dos fármacos
Linfócitos/imunologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Metals); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:0808
[Cu] Atualização por classe:080515
[Lr] Data última revisão:
080515
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:080102
[St] Status:MEDLINE
[do] DOI:10.1007/s00244-007-9092-3


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[PMID]:17489621
[Au] Autor:Li Y; Yan XP; Chen C; Xia YL; Jiang Y
[Ad] Endereço:Key Laboratory of Functional Polymer Materials (Nankai University), Ministry of Education; Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin 300071, China.
[Ti] Título:Human serum albumin-mercurial species interactions.
[So] Source:J Proteome Res;6(6):2277-86, 2007 Jun.
[Is] ISSN:1535-3893
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Binding of metal ions to the heteroatomic sites of proteins is undoubtedly fundamental to their observed physiological effects. In this paper, the interactions of inorganic mercury (Hg2+), methylmercury (MeHg+), ethylmercury (EtHg+), and phenylmercury (PhHg+) with human serum albumin (HSA) were studied from the electrophoretic behaviors, stoichiometry, thermodynamics, and kinetics by using a new hybrid technique, capillary electrophoresis on-line coupled with electrothermal atomic absorption spectrometry (CE-ETAAS), together with the consequent structural information from circular dichroism and Raman spectroscopy. The stoichiometry (mercurial species to HSA) for the interactions of Hg2+, MeHg+, EtHg+, and PhHg+ with HSA was found to be 6:1, 4:1, 4:1, and 3:1, respectively. Two types of binding sites in HSA were observed for the binding of mercurial species with the orders of magnitude of binding constants of 10(7) and 10(6) L mol-1, respectively, showing strong affinity of mercurial species for HSA. The interactions of mercurial species with both types of binding sites in HSA are exothermic and thermodynamically favorable and are both enthalpically and entropically driven. The binding of mercurial species to HSA follows the first-order kinetics for mercurial species and zero-order kinetics for HSA with the apparent activation energy of 57-59 kJ mol-1. Among the four mercurial species examined, only Hg2+ induces the secondary structure transition of HSA. Mercury-HSA adducts are formed mainly through metal-sulfur binding with participation of C=O and/or C-N groups of amino acid residues in HSA molecules. The present work represents the most comprehensive study on the interactions between various mercurial species with HSA and provides new evidence for and insights into the interactions of mercurial species with HSA for further understanding of the toxicological effects of mercurial species.
[Mh] Termos MeSH primário: Compostos de Alquilmercúrio/química
Albumina Sérica/química
[Mh] Termos MeSH secundário: Dicroísmo Circular
Eletroforese Capilar
Seres Humanos
Cinética
Espectrofotometria Atômica
Análise Espectral Raman
Termodinâmica
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Alkylmercury Compounds); 0 (Serum Albumin)
[Em] Mês de entrada:0707
[Cu] Atualização por classe:070601
[Lr] Data última revisão:
070601
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:070511
[St] Status:MEDLINE



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BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde