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[PMID]: 28462719 [Au] Autor: Hung TJ; Burrage J; Bourke A; Taylor D [Ad] Endereço: Department of Nuclear Medicine, Royal Perth Hospital, Perth. Australia. [Ti] Título: Intraoperative Localisation of Impalpable Breast Lesions Utilising the ROLLIS Technique Following Peritumoral 99mTc-colloid Sentinel Node Lymphoscintigraphy. [So] Source: Curr Radiopharm;10(2):111-114, 2017 Aug 24. [Is] ISSN: 1874-4729 [Cp] País de publicação: United Arab Emirates [La] Idioma: eng [Ab] Resumo: BACKGROUND: Ultrasound or stereotactic guided hook-wire localisation has been the standard-of-care for the pre-surgical localisation of impalpable breast lesions, which account for approximately a third of all breast cancer. Radioguided occult lesion localisation using I-125 seeds (ROLLIS) is a relatively new technique for guiding surgical excision of impalpable breast lesions, and is a promising alternative to the traditional hook-wire method. When combined with Tc-99m labelled colloid for sentinel node mapping in clinically indicated cases, there has been uncertainty regarding whether the downscatter of Tc-99m into the I-125 energy spectrum could adversely affect the intra-operative detection of the I-125 seed, especially pertaining to a peritumoral injection. OBJECTIVE: To evaluate the percentage contribution of downscattered activity from Tc-99m into the I-125 energy spectrum in simulated intra-operative resections of an I-125 seed following different sentinel node injection techniques. METHOD: Two scenarios were simulated using breast phantoms with lean chicken breast. The first scenario, with a 2cm distance between the Tc-99m injection site and the I-125 seed, simulated a periareolar ipsiquadrant injection with the subdermal or intradermal technique. The second scenario simulated a peritumoral injection technique with the Tc-99m bolus and an I-125 seed at the same site. Count rates were acquired with a hand-held gamma probe, and the percentage contribution of downscattered Tc-99m gamma photons to the I-125 energy window was calculated. RESULTS: In scenarios one and two, downscattered Tc-99m activity contributed 0.5% and 33% respectively to the detected count rate in the I-125 energy window. In both scenarios, the I-125 seed was successfully localised and removed using the gamma probe. CONCLUSION: There is no significant contribution of downscattered activity associated with a peritumoral injection of Tc-99m to adversely affect the accurate intra-operative localisation of an I- 125 seed. [Mh] Termos MeSH primário: Neoplasias da Mama/diagnóstico por imagem Neoplasias da Mama/cirurgia Linfocintigrafia Cintilografia/métodos [Mh] Termos MeSH secundário: Neoplasias da Mama/patologia Marcadores Fiduciais Período Intraoperatório Radioisótopos do Iodo Metástase Linfática/diagnóstico por imagem Imagens de Fantasmas Compostos Radiofarmacêuticos Espalhamento de Radiação Sensibilidade e Especificidade Pertecnetato Tc 99m de Sódio Agregado de Albumina Marcado com Tecnécio Tc 99m Resultado do Tratamento [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Iodine Radioisotopes); 0 (Iodine-125); 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin); 0 (technetium Tc 99m nanocolloid); A0730CX801 (Sodium Pertechnetate Tc 99m) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180215 [Lr] Data última revisão: 180215 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170503 [St] Status: MEDLINE [do] DOI: 10.2174/1874471010666170428113052

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[PMID]: 28982888 [Au] Autor: Morine Y; Enkhbold C; Imura S; Ikemoto T; Iwahashi S; Saito YU; Yamada S; Utsunomiya T; Shimada M [Ad] Endereço: Department of Surgery, Institute of Biochemical Sciences, Tokushima University Graduate School, Tokushima, Japan ymorine@tokushima-u.ac.jp. [Ti] Título: Accurate Estimation of Functional Liver Volume Using Gd-EOB-DTPA MRI Compared to MDCT/ Tc-SPECT Fusion Imaging. [So] Source: Anticancer Res;37(10):5693-5700, 2017 10. [Is] ISSN: 1791-7530 [Cp] País de publicação: Greece [La] Idioma: eng [Ab] Resumo: BACKGROUND/AIM: We assessed the utility of dynamic magnetic resonance imaging (MRI) with gadoxetate-ethoxybenzyl-diethylenetriamine penta-aceticpenta-acetic acid (Gd-EOB-DTPA) (EOB-MRI) for estimating functional liver volume compared to Tc-galactosyl albumin single-photon-emission computed tomography ( Tc-GSA SPECT). PATIENTS AND METHODS: Regional functional liver volume (left lateral, medial, right anterior, right posterior) of 58 hepatectomized patients was assessed using EOB-MRI and Tc-GSA SPECT, and compared to the actual liver volume with MDCT-3D volumetry. RESULTS: Tc-GSA SPECT found a significantly lower functional volume of the left lateral section than the actual volume found by MDCT-3D volumetry (p=0.003) and EOB-MRI (p<0.001). Functional liver volume of right anterior section found with Tc-GSA SPECT was significantly higher than that found by MDCT-3D volumetry (p=0.04), despite no differences in asialoglycoprotein receptor 1 (ASGR1) or ATP-dependent organic anion transporting polypeptide 1 (OATP) expression between the left lateral and right anterior sections. CONCLUSION: Tc-GSA SPECT might underestimate the function of the left lobe and overestimate that of the right lobe. Therefore, EOB-MRI could be better for estimating the true regional functional liver reserve. [Mh] Termos MeSH primário: Meios de Contraste/administração & dosagem Gadolínio DTPA/administração & dosagem Fígado/diagnóstico por imagem Imagem por Ressonância Magnética/métodos Tomografia Computadorizada Multidetectores Compostos Radiofarmacêuticos/administração & dosagem Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/métodos Agregado de Albumina Marcado com Tecnécio Tc 99m/administração & dosagem Pentetato de Tecnécio Tc 99m/administração & dosagem [Mh] Termos MeSH secundário: Adulto Idoso Idoso de 80 Anos ou mais Receptor de Asialoglicoproteína/análise Biomarcadores/análise Biópsia Feminino Hepatectomia Seres Humanos Imuno-Histoquímica Fígado/química Fígado/cirurgia Masculino Meia-Idade Tamanho do Órgão Transportadores de Ânions Orgânicos/análise Valor Preditivo dos Testes Reprodutibilidade dos Testes [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: 0 (ASGR1 protein, human); 0 (Asialoglycoprotein Receptor); 0 (Biomarkers); 0 (Contrast Media); 0 (Organic Anion Transporters); 0 (Radiopharmaceuticals); 0 (SLCO1A2 protein, human); 0 (Technetium Tc 99m Aggregated Albumin); 0 (gadolinium ethoxybenzyl DTPA); 0 (technetium Tc 99m DTPA-galactosyl-human serum albumin); K2I13DR72L (Gadolinium DTPA); VW78417PU1 (Technetium Tc 99m Pentetate) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171016 [Lr] Data última revisão: 171016 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171007 [St] Status: MEDLINE

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[PMID]: 28877348 [Au] Autor: Karakatsanis A; Daskalakis K; Stålberg P; Olofsson H; Andersson Y; Eriksson S; Bergkvist L; Wärnberg F [Ad] Endereço: Department of Surgical Sciences, Uppsala University Hospital, Uppsala Academic Hospital, Uppsala, Sweden. [Ti] Título: Superparamagnetic iron oxide nanoparticles as the sole method for sentinel node biopsy detection in patients with breast cancer. [So] Source: Br J Surg;104(12):1675-1685, 2017 Nov. [Is] ISSN: 1365-2168 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: BACKGROUND: Sentinel node biopsy (SNB) using superparamagnetic iron oxide (SPIO) nanoparticles is a novel method in breast cancer. Several studies have verified the non-inferiority of SPIO compared with the standard use of radioisotope Tc with or without blue dye. The aim of the MONOS study presented here was to evaluate the use of SPIO as a sole tracer and the efficacy of tracer injection in the preoperative setting. METHODS: This prospective cohort study was carried out in two hospitals, one using Tc and the other SPIO. Tc was injected in the morning of the day of surgery or the day before. SPIO was either injected before surgery in the outpatient clinic or 1 h before the operation. RESULTS: A total of 338 consecutive patients with breast cancer underwent 343 procedures; SPIO nanoparticles were used in 184 procedures and Tc-labelled tracer in 159. Detection rates for SPIO and Tc were 95·6 and 96·9 per cent respectively (P = 0·537). All nodes with SPIO uptake were coloured brown. Fewer nodes were retrieved with SPIO (mean 1·35 versus 1·89), regardless of whether blue dye was used (P < 0·001). Preoperative SPIO injection (58·7 per cent of procedures), a median of 16 (range 2-27) days before the procedure, was associated with a better tracer-specific detection rate (95·3 versus 86 per cent; P = 0·031) and retrieval of more nodes (mean 1·43 versus 1·03; P < 0·001) than perioperative administration. Skin staining was present in 39·9 per cent of patients, and was related to breast-conserving surgery and periareolar injection. CONCLUSION: The use of SPIO alone is a safe alternative, with results comparable to those of the standard dual technique using Tc and blue dye. The efficacy of injection in the preoperative setting simplifies logistics and improves performance. Skin staining can be prevented by a deeper peritumoral injection. [Mh] Termos MeSH primário: Neoplasias da Mama/patologia Neoplasias da Mama/cirurgia Compostos Férricos Linfonodos/patologia Nanopartículas de Magnetita Biópsia de Linfonodo Sentinela/métodos [Mh] Termos MeSH secundário: Idoso Corantes Custos e Análise de Custo Feminino Compostos Férricos/efeitos adversos Seres Humanos Metástase Linfática Nanopartículas de Magnetita/efeitos adversos Mastectomia Segmentar Meia-Idade Satisfação do Paciente Transtornos da Pigmentação/etiologia Estudos Prospectivos Cintilografia Biópsia de Linfonodo Sentinela/economia Agregado de Albumina Marcado com Tecnécio Tc 99m [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Coloring Agents); 0 (Ferric Compounds); 0 (Magnetite Nanoparticles); 0 (Technetium Tc 99m Aggregated Albumin); 1K09F3G675 (ferric oxide) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171025 [Lr] Data última revisão: 171025 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170907 [St] Status: MEDLINE [do] DOI: 10.1002/bjs.10606

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[PMID]: 28537788 [Au] Autor: Dunphy M; Pandit-Taskar N; Fox JJ; Kemeny N [Ad] Endereço: 1 Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065. [Ti] Título: The Precision of Hepatic Arterial Infusion Scintigraphy as a Quantitative Biomarker of Tumor Microvasculature. [So] Source: AJR Am J Roentgenol;209(1):182-186, 2017 Jul. [Is] ISSN: 1546-3141 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: Optimal clinical development of new cancer therapies targeting tumor vasculature requires new target-specific response assays. This clinical study examined the test-retest repeatability of SPECT as an in vivo assay of angiogenic hepatic tumor microvasculature using an intraarterial infusion of Tc-macroaggregated albumin (MAA) delivered via a hepatic artery infusion (HAI) pump. MATERIALS AND METHODS: Patients with primary or secondary cancerous liver tumors with HAI pump-catheter implants placed for HAI chemotherapy underwent hepatic SPECT after separate arterial infusions of 37 and 185 MBq of Tc-MAA via an HAI pump. Quantitative measures of hepatic tumor MAA uptake were obtained from paired test-retest SPECT datasets. Repeatability was defined by quotients of paired measurands with 95% CIs and coefficients of repeatability (CRs). RESULTS: Test-retest HAI pump SPECT yielded highly repeatable measurements in quantitative indexes of tumor microvasculature. Variability in repeat test-retest measurements was small relative to the range of observed measurements between different tumors. The total hepatic tumor microvascular MAA accumulation (percentage injected dose) proved most repeatable, with test-retest value quotients near unity (quotients: median, 1.10 ± 0.09 [SD]; range, 1.03-1.32; 95% CI, 1.07-1.19) and 1.6% CR. Tumor MAA uptake values ranged from 5% to 18% injected dose. CONCLUSION: This article describes the precision of HAI SPECT as a quantitative biomarker of tumor microvasculature under conditions of repeatability. The results support clinical testing of HAI SPECT as a radiologic response biomarker for angiotropic tumor therapy. [Mh] Termos MeSH primário: Inibidores da Angiogênese/administração & dosagem Artéria Hepática Neoplasias Hepáticas/diagnóstico por imagem Neoplasias Hepáticas/tratamento farmacológico Neovascularização Patológica/diagnóstico por imagem Neovascularização Patológica/tratamento farmacológico Compostos Radiofarmacêuticos/administração & dosagem Agregado de Albumina Marcado com Tecnécio Tc 99m/administração & dosagem Tomografia Computadorizada de Emissão de Fóton Único/métodos [Mh] Termos MeSH secundário: Idoso Feminino Seres Humanos Masculino Microesferas Meia-Idade Reprodutibilidade dos Testes [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Angiogenesis Inhibitors); 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin) [Em] Mês de entrada: 1708 [Cu] Atualização por classe: 170902 [Lr] Data última revisão: 170902 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170525 [St] Status: MEDLINE [do] DOI: 10.2214/AJR.16.17560

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[PMID]: 28315911 [Au] Autor: El-Barhoun EN; Chew G; Crouch B; Chatterton B [Ad] Endereço: Department of Nuclear Medicine, Royal Adelaide Hospital, North Tce, Adelaide, South Australia, Australia. Esber.El-Barhoun@sa.gov.au. [Ti] Título: Reproducibility of a semi-quantitative lobar pulmonary ventilation and perfusion technique using SPET and CT. [So] Source: Hell J Nucl Med;20(1):71-75, 2017 Jan-Apr. [Is] ISSN: 1790-5427 [Cp] País de publicação: Greece [La] Idioma: eng [Ab] Resumo: OBJECTIVE: Evaluation of regional lung function is valuable prior to lung surgery in patients with chronic lung disease. Our aim was to evaluate the reproducibility of a locally developed single photon emission tomography/computed tomography (SPET/CT) programme between and within three observers in assessing lobar pulmonary volumes, perfusion and ventilation. SUBJECTS AND METHODS: Twelve lung transplantation candidates had VQ SPET and diagnostic CT to determine lobar pulmonary function and plan surgery. Their data were used retrospectively in an in-house developed programme which delineates the lung fissures on the diagnostic CT as an anatomical template used to estimate the volume of each of 5 lung lobes. These anatomical volumes were then applied to the corresponding ventilation ( Tc technegas) and perfusion ( Tc MAA) SPET studies. The data were anonymised, duplicated and then processed in random order blindly by 3 readers several weeks apart. Nine studies could be adequately processed. The programme failed in delineating lung volumes in 2 subjects and there was data corruption in the third. The results were evaluated for inter- and intra- observer variability using an intra-class Correlation Coefficient (ICC). An ICC score was calculated for each lobe for volume, ventilation and perfusion. RESULTS: Inter- and intra- observer ICC scores for ventilation, and perfusion scans were all very high. Similar very strong ICC concordance scores were noted for volume except intra-observer ICC scores for left upper lobe (0.76) and right mid lobe (0.66) where scores showed strong concordance by standard statistical descriptors. The method was sensitive enough to demonstrate the expected gradient of ventilation/perfusion even in these patients with substantial pathology. CONCLUSION: Our method of lobar VQ SPET with CT quantitation has high inter- and intra- observer concordance and in this preliminary data set seems to be a reliable and reproducible test for semi-quantitation of differential volume, ventilation and perfusion of the lobes of the lungs. [Mh] Termos MeSH primário: Pulmão/diagnóstico por imagem Pulmão/fisiopatologia Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/métodos Pertecnetato Tc 99m de Sódio Agregado de Albumina Marcado com Tecnécio Tc 99m Relação Ventilação-Perfusão [Mh] Termos MeSH secundário: Algoritmos Seres Humanos Aumento da Imagem/métodos Interpretação de Imagem Assistida por Computador/métodos Variações Dependentes do Observador Reconhecimento Automatizado de Padrão/métodos Compostos Radiofarmacêuticos Reprodutibilidade dos Testes Sensibilidade e Especificidade Software [Pt] Tipo de publicação: EVALUATION STUDIES; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin); 112263-77-1 (Technegas); A0730CX801 (Sodium Pertechnetate Tc 99m) [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170619 [Lr] Data última revisão: 170619 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170320 [St] Status: MEDLINE [do] DOI: 10.1967/s002449910509

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[PMID]: 28238581 [Au] Autor: Haste P; Tann M; Persohn S; LaRoche T; Aaron V; Mauxion T; Chauhan N; Dreher MR; Johnson MS [Ad] Endereço: Department of Radiology, Indiana University School of Medicine, 550 N. University Boulevard, Room 0663, Indianapolis, IN 46202. Electronic address: pmhaste@gmail.com. [Ti] Título: Correlation of Technetium-99m Macroaggregated Albumin and Yttrium-90 Glass Microsphere Biodistribution in Hepatocellular Carcinoma: A Retrospective Review of Pretreatment Single Photon Emission CT and Posttreatment Positron Emission Tomography/CT. [So] Source: J Vasc Interv Radiol;28(5):722-730.e1, 2017 May. [Is] ISSN: 1535-7732 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: PURPOSE: To evaluate whether technetium-99 ( Tc)-labeled macroaggregated albumin (MAA) can predict subsequent yttrium-90 ( Y) distribution and imaging response in patients with hepatocellular carcinoma (HCC). MATERIALS: Retrospective review was performed of records of 83 patients with HCC who underwent Y glass microsphere radioembolization with Tc-MAA single photon emission computed tomography (SPECT) and Y positron emission tomography (PET)/CT between January 2013 and December 2014. Images were fused to segment the whole liver normal tissue (WLNT) and the largest tumors. Fused images were reviewed and analyzed for comparison of absorbed dose (AD) to tumors and WLNT as calculated from Tc-MAA SPECT and from Y PET/CT, subjective imaging comparison of Tc-MAA SPECT and Y PET for tumors and WLNT, and correlation of tumoral AD with response on follow-up CT. RESULTS: Final analysis included 73 and 63 patients for WLNT and tumor Tc-MAA/ Y correlation, respectively, and 62 patients for AD vs response. Tc-MAA/ Y limit of agreement for each reviewer was viewed as clinically acceptable only for WLNT (-15 to 15 Gy). AD interreviewer variability was clinically acceptable for WLNT but was too broad for tumor. Mean tumor AD for objective response (78%) was 313 Gy vs 234 Gy for nonresponders. No threshold was found between tumor AD and response (P > .1). Catheter mismatch between Tc-MAA and Y had a direct impact on AD mismatch between the 2 image sets. CONCLUSIONS: Tc-MAA was found to be a poor surrogate to quantitatively predict subsequent Y AD to hepatocellular tumors. Tc-MAA distribution correlated with Y distribution in the normal hepatic parenchyma. [Mh] Termos MeSH primário: Carcinoma Hepatocelular/diagnóstico por imagem Neoplasias Hepáticas/diagnóstico por imagem Tomografia Computadorizada com Tomografia por Emissão de Pósitrons Compostos Radiofarmacêuticos/farmacocinética Agregado de Albumina Marcado com Tecnécio Tc 99m/farmacocinética Tomografia Computadorizada de Emissão de Fóton Único Radioisótopos de Ítrio/farmacocinética [Mh] Termos MeSH secundário: Idoso Idoso de 80 Anos ou mais Feminino Seres Humanos Masculino Microesferas Meia-Idade Estudos Retrospectivos Distribuição Tecidual [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin); 0 (Yttrium Radioisotopes) [Em] Mês de entrada: 1710 [Cu] Atualização por classe: 171024 [Lr] Data última revisão: 171024 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170228 [St] Status: MEDLINE

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[PMID]: 28120090 [Au] Autor: Stevanato G; Monteleone G; Sgubin D; Sicolo M; Pastorello G; Vazzana L; Guida F [Ad] Endereço: Neurosurgery Unit, Dell'Angelo Hospital, Via Paccagnella 11, Mestre-Venezia, 30172, Italy. giorgio.stevanato@ulss12.ve.it. [Ti] Título: Radioguided Occult Lesion Localization in Deep Schwannomas of the Peripheral Nerves: Results of a Preliminary Case Series. [So] Source: Acta Neurochir Suppl;124:315-318, 2017. [Is] ISSN: 0065-1419 [Cp] País de publicação: Austria [La] Idioma: eng [Ab] Resumo: BACKGROUND: The detection of small deep schwannomas of the peripheral nerves has been increasing since the the use of precise neuroimaging techniques has become more widespread; however, although nonpalpable lesions can be well defined by images, it is often difficult to identify them during the surgical procedure. The authors report seven cases of nonpalpable small deep schwannomas surgically treated after their identification using the radioguided occult lesion localization (ROLL) technique. METHODS: Seven men, whose ages ranged from 34 to 70 years (mean 52 years), presented with symptomatic nonpalpable peripheral nerve lesions; two cases involved the sciatic nerve, two the femoral nerve, two the radial nerve, and one the tibial nerve. Before the operation, all the patients were studied by ultrasonography and magnetic resonance imaging (MRI); 1 h before the surgery 3-5 MBq of Tc labeled with human albumin macroaggregates was injected into the lesion. A gamma detection probe permitted the preoperative and intraoperative detection of the nonpalpable schwannomas. CONCLUSIONS: The ROLL technique provides good support for identifying small lesions of the peripheral nerves both preoperatively and intraoperatively. This technique permits the use of minimally invasive approaches performed with local anesthesia, with good cosmetic results and acceptance by the patients. [Mh] Termos MeSH primário: Neuropatia Femoral/cirurgia Neurilemoma/cirurgia Neoplasias do Sistema Nervoso Periférico/cirurgia Neuropatia Radial/cirurgia Neuropatia Ciática/cirurgia Neuropatia Tibial/cirurgia [Mh] Termos MeSH secundário: Adulto Idoso Feminino Neuropatia Femoral/diagnóstico por imagem Seres Humanos Masculino Meia-Idade Neurilemoma/diagnóstico por imagem Procedimentos Neurocirúrgicos Neoplasias do Sistema Nervoso Periférico/diagnóstico por imagem Neuropatia Radial/diagnóstico por imagem Compostos Radiofarmacêuticos Neuropatia Ciática/diagnóstico por imagem Agregado de Albumina Marcado com Tecnécio Tc 99m Neuropatia Tibial/diagnóstico por imagem Ultrassonografia [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin) [Em] Mês de entrada: 1711 [Cu] Atualização por classe: 171102 [Lr] Data última revisão: 171102 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170126 [St] Status: MEDLINE [do] DOI: 10.1007/978-3-319-39546-3_46

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[PMID]: 28102814 [Au] Autor: Uchida T; Yamada Y; Imakiire T; Oshima N; Kumagai H [Ti] Título: Successful induction of peritoneal dialysis in a patient with massive hydrothorax due to pleuroperitoneal communication
. [So] Source: Clin Nephrol;87 (2017)(4):202-206, 2017 Apr. [Is] ISSN: 0301-0430 [Cp] País de publicação: Germany [La] Idioma: eng [Ab] Resumo: A 74-year-old woman with liver cirrhosis and chronic kidney disease (CKD) who had complained of chronic abdominal distension due to prominent ascites presented with sudden dyspnea. Chest radiography showed massive right pleural effusion that shifted the mediastinum. Peritoneal scintigraphy using 99mTc-macroaggregated albumin revealed pleuroperitoneal communication (PPC). As her hydrothorax was refractory and frequent thoracentesis did not improve her respiratory distress, thoracoscopic surgery was performed for repair of the diaphragm defect. Continuous ambulatory peritoneal dialysis (CAPD) was started soon after surgery because her renal function was progressively worsening, and there was no recurrence of hydrothorax. The chronic abdominal distension resolved as her ascites decreased. In addition, peritoneal protein loss decreased after initiation of peritoneal dialysis (PD). PPC is an uncommon but serious complication of PD, and PD patients with PPC are often forced to discontinue PD. To our knowledge, no report has presented successful PD induction in a patient with evident PPC. We believe that further accumulation of such cases will expand the treatment options for CKD.
. [Mh] Termos MeSH primário: Ascite/terapia Diafragma/cirurgia Hidrotórax/terapia Falência Renal Crônica/terapia Cirrose Hepática Diálise Peritoneal Ambulatorial Contínua/métodos [Mh] Termos MeSH secundário: Idoso Ascite/diagnóstico por imagem Ascite/etiologia Progressão da Doença Feminino Seres Humanos Hidrotórax/diagnóstico por imagem Hidrotórax/etiologia Falência Renal Crônica/complicações Cirrose Hepática/complicações Recidiva Insuficiência Renal Crônica/complicações Insuficiência Renal Crônica/terapia Albumina Sérica Agregado de Albumina Marcado com Tecnécio Tc 99m Toracoscopia Compostos de Estanho [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Serum Albumin); 0 (Technetium Tc 99m Aggregated Albumin); 0 (Tin Compounds); 0 (technetium Tc 99m-Sn aggregated albumin) [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170602 [Lr] Data última revisão: 170602 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170120 [St] Status: MEDLINE [do] DOI: 10.5414/CN108887

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[PMID]: 28095020 [Au] Autor: Metter D; Tulchinsky M; Freeman LM [Ad] Endereço: 1 Department of Radiology, University of Texas Health Science Center San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229. [Ti] Título: Current Status of Ventilation-Perfusion Scintigraphy for Suspected Pulmonary Embolism. [So] Source: AJR Am J Roentgenol;208(3):489-494, 2017 Mar. [Is] ISSN: 1546-3141 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: The purpose of this article is to outline recent progress made in ventilation-perfusion (V/Q) scintigraphy imaging techniques and the interpretation systems used for the diagnosis of pulmonary embolism (PE). Various state-of-the-art approaches that can be selected according to the needs dictated by the medical practice environment and specific patient groups are presented. CONCLUSION: Although advances in tomographic imaging have certainly improved the sensitivity of V/Q scans for the diagnosis of PE, they may lead to overdiagnosis by revealing small and clinically insignificant PEs. [Mh] Termos MeSH primário: Aumento da Imagem/métodos Interpretação de Imagem Assistida por Computador/métodos Embolia Pulmonar/diagnóstico por imagem Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/métodos Agregado de Albumina Marcado com Tecnécio Tc 99m Relação Ventilação-Perfusão [Mh] Termos MeSH secundário: Medicina Baseada em Evidências Seres Humanos Compostos Radiofarmacêuticos Reprodutibilidade dos Testes Sensibilidade e Especificidade [Pt] Tipo de publicação: JOURNAL ARTICLE; REVIEW [Nm] Nome de substância: 0 (Radiopharmaceuticals); 0 (Technetium Tc 99m Aggregated Albumin) [Em] Mês de entrada: 1704 [Cu] Atualização por classe: 170403 [Lr] Data última revisão: 170403 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170118 [St] Status: MEDLINE [do] DOI: 10.2214/AJR.16.17195

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MEDLINE

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[PMID]: 28002156 [Au] Autor: Nishino A; Hanaoka M; Katsumata Y; Kawaguchi Y; Yamanaka H [Ad] Endereço: From the Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan. [Ti] Título: Technetium-99m Albumin Scintigraphy in Protein-Losing Gastroenteropathy With Systemic Lupus Erythematosus: Typical Diagnostic Pattern of Radiotracer Leakage and Chronological Improvement by Treatment. [So] Source: J Clin Rheumatol;23(1):41-42, 2017 Jan. [Is] ISSN: 1536-7355 [Cp] País de publicação: United States [La] Idioma: eng [Mh] Termos MeSH primário: Trato Gastrointestinal Glucocorticoides/administração & dosagem Hipoalbuminemia Lúpus Eritematoso Sistêmico Enteropatias Perdedoras de Proteínas Cintilografia/métodos [Mh] Termos MeSH secundário: Adulto Diagnóstico Diferencial Trato Gastrointestinal/diagnóstico por imagem Trato Gastrointestinal/patologia Seres Humanos Hipoalbuminemia/diagnóstico Hipoalbuminemia/etiologia Lúpus Eritematoso Sistêmico/complicações Lúpus Eritematoso Sistêmico/diagnóstico Masculino Enteropatias Perdedoras de Proteínas/complicações Enteropatias Perdedoras de Proteínas/diagnóstico Agregado de Albumina Marcado com Tecnécio Tc 99m [Pt] Tipo de publicação: CASE REPORTS; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Glucocorticoids); 0 (Technetium Tc 99m Aggregated Albumin) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170724 [Lr] Data última revisão: 170724 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161222 [St] Status: MEDLINE [do] DOI: 10.1097/RHU.0000000000000482

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