Base de dados : MEDLINE
Pesquisa : D02.705.400.625.220 [Categoria DeCS]
Referências encontradas : 682 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 69 ir para página                         

  1 / 682 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28764001
[Au] Autor:Hou R; Tong M; Gao W; Wang L; Yang T; He L
[Ad] Endereço:China State Key Laboratory of Tea Plant Biology and Utilization, School of Tea and Food Science & Technology, Anhui Agricultural University, Hefei 230036, PR China; Department of Food Science, University of Massachusetts, Amherst, MA, USA. Electronic address: hry@ahau.edu.cn.
[Ti] Título:Investigation of degradation and penetration behaviors of dimethoate on and in spinach leaves using in situ SERS and LC-MS.
[So] Source:Food Chem;237:305-311, 2017 Dec 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:To investigate the degradation and penetration behaviors of the organophosphate insecticide dimethoate applied on spinach leaves, in situ SERS and LC-MS methods were used to detect dimethoate residue on&in spinach leaves picked on different days after treatment (DAT). The SERS and LC-MS methods determined that the dimethoate degradation rate followed first-order kinetics, with a half-life of 3.56 or 4.13days, depending on the respective method. The correlation coefficient of quantification value of these two methods was 0.9562. With the SERS method, we detected most of the penetrated dimethoate in the depth of 60-110µm. With the LC-MS method, we detected dimethoate up to 0.17ng in leaves and that the dimethoate on:in ratio of spinach leaves ranged from 562.25 on 0 DAT to 5.23 on 14 DAT. The combination of these two methods facilitated a better understanding of the behavior and biological fate of pesticides in a complex biological system.
[Mh] Termos MeSH primário: Spinacia oleracea/química
[Mh] Termos MeSH secundário: Cromatografia Líquida
Dimetoato
Espectrometria de Massas
Praguicidas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Pesticides); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171102
[Lr] Data última revisão:
171102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE


  2 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28718371
[Au] Autor:Duan X; Yang Y; Wang S; Feng X; Wang T; Wang P; Liu S; Li L; Yao W; Cui L; Wang W
[Ad] Endereço:1 Department of Occupational and Environmental Health, College of Public Health, Zhengzhou University, Zhengzhou, China.
[Ti] Título:Changes in the expression of genes involved in cell cycle regulation and the relative telomere length in the process of canceration induced by omethoate.
[So] Source:Tumour Biol;39(7):1010428317719782, 2017 Jul.
[Is] ISSN:1423-0380
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Organophosphorous pesticides (OPs), with high efficiency, broad-spectrum and low residue, are widely used in China. Omethoate is a broad category of organophosphorous pesticides and is more domestically utilized which has chronic toxic effect on human health caused by long-term, low-dose exposure to Ops, recently its potential genotoxicity has attracted wide attention which can cause chromosomal DNA damage. Thus, the aim of this study is screen susceptible biomarkers and explore the mechanism of canceration induced by omethoate. 180 long-term organophosphorus pesticide-exposed workers and 115 healthy controls were recruited. Quantitative polymerase chain reaction method was applied to determine the relative telomere length in peripheral lymphocyte DNA as well as p53 and p21 gene expression levels. Genetic polymorphisms were determined by the polymerase chain reaction-restriction fragment length polymorphism method. Multiple linear regression was conducted to explore the effects of exposure, expression levels, and polymorphisms in genes on the telomere length. The results showed the relative telomere lengths in the exposure group were significantly longer than that in the control group. The messenger RNA expression levels of p53 and p21 in exposure group were significantly lower than that in the control group; telomere lengths of the CA genotype individuals of p21 rs1801270 polymorphism locus were significantly longer than that of the CC genotype in the control group that were estimated using the Bonferroni method; and bivariate correlation analysis showed that the messenger RNA expression level of gene p53 was negatively correlated with telomere length, and the messenger RNA expression level of gene p21 was positively correlated with telomere length. Multivariate analysis found that p53 messenger RNA and p21 messenger RNA had an impact on telomere length. These results demonstrated that the messenger RNA expression levels of p53 and p21 may have a relationship with the changes in telomere length induced by omethoate and provided strong evidence for the mechanism of canceration induced by poison.
[Mh] Termos MeSH primário: Carcinogênese/efeitos dos fármacos
Inibidor de Quinase Dependente de Ciclina p21/genética
Neoplasias/genética
Proteína Supressora de Tumor p53/genética
[Mh] Termos MeSH secundário: Adulto
Ciclo Celular/efeitos dos fármacos
China
Inibidor de Quinase Dependente de Ciclina p21/biossíntese
Dano ao DNA/efeitos dos fármacos
Dimetoato/análogos & derivados
Dimetoato/toxicidade
Feminino
Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos
Genótipo
Seres Humanos
Linfócitos/efeitos dos fármacos
Linfócitos/patologia
Masculino
Meia-Idade
Neoplasias/induzido quimicamente
Neoplasias/patologia
Exposição Ocupacional
Polimorfismo de Nucleotídeo Único
RNA Mensageiro/biossíntese
RNA Mensageiro/genética
Homeostase do Telômero/efeitos dos fármacos
Proteína Supressora de Tumor p53/biossíntese
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (CDKN1A protein, human); 0 (Cyclin-Dependent Kinase Inhibitor p21); 0 (RNA, Messenger); 0 (TP53 protein, human); 0 (Tumor Suppressor Protein p53); 28U28EWE79 (dimethoxon); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170719
[St] Status:MEDLINE
[do] DOI:10.1177/1010428317719782


  3 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28334350
[Au] Autor:George A; Rao CN; Ghike S; Dhengre V
[Ad] Endereço:Scientist, Entomology, ICAR-Central Citrus Research Institute, Nagpur 440033, Maharashtra, India (anjithakitty@gmail.com).
[Ti] Título:Relative Susceptibility of Phyllocnistis citrella (Lepidoptera: Gracillariidae) to Commonly Used Insecticides in Maharashtra, India.
[So] Source:J Econ Entomol;110(2):525-529, 2017 Apr 01.
[Is] ISSN:1938-291X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Foliar application of insecticides has been the most commonly followed practice to manage Phyllocnistis citrella Stainton in nurseries and flush leaves in citrus groves. Leaf dip bioassays were conducted against insecticides, viz., acephate 75SP, dimethoate 30EC, abamectin 1.9EC, fenvalerate 20EC, imidacloprid 17.8SL, and thiamethoxam 25WG, and were tested against P. citrella larvae for their susceptibility. Among six insecticides tested on second-instar P. citrella larvae collected from Nagpur mandarin/acid lime cultivars during 2013-2016, abamectin was the most toxic insecticide for the initial year (LC50 values ranged from 20.99 to 49.00 ppm), while dimethoate (LC50 of 36.57-160.95 ppm) and thiamethoxam (39.90-71.96 ppm) were consistently effective against P. citrella larvae for the rest of the period. Resistance ratio (RR) values calculated based on the baseline susceptible culture, viz., abamectin (1.24-2.33), acephate (1.03-2.31), fenvalerate (1.54-3.45), dimethoate(1.28-5.63), imidacloprid (1.29-8.64), and thiamethoxam (1.05-1.80), indicated that the current RR values were in low levels (RR < 10).
[Mh] Termos MeSH primário: Proteção de Cultivos/métodos
Inseticidas/farmacologia
Mariposas/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Dimetoato/farmacologia
Imidazóis/farmacologia
Índia
Ivermectina/análogos & derivados
Ivermectina/farmacologia
Larva/efeitos dos fármacos
Neonicotinoides
Nitrilos/farmacologia
Nitrocompostos/farmacologia
Oxazinas/farmacologia
Piretrinas/farmacologia
Tiazóis/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Imidazoles); 0 (Insecticides); 0 (Neonicotinoids); 0 (Nitriles); 0 (Nitro Compounds); 0 (Oxazines); 0 (Pyrethrins); 0 (Thiazoles); 3BN7M937V8 (imidacloprid); 5U8924T11H (abamectin); 70288-86-7 (Ivermectin); 747IC8B487 (thiamethoxam); W6U08B045O (Dimethoate); Z6MXZ39302 (fenvalerate)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1093/jee/tow311


  4 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28334254
[Au] Autor:Alam M; Waqas Sumra M; Ahmad D; Shah RM; Binyameen M; Ali Shad S
[Ad] Endereço:Department of Entomology, Faculty of Agriculture Sciences & Technology, Bahauddin Zakariya University, Multan 60800, Pakistan (mehboob61ento@gmail.com; waqassumra33@gmail.com; enchanticboy@yahoo.com; rizwanmustafa20@gmail.com; mbinyameen@bzu.edu.pk; sarfrazshad@bzu.edu.pk).
[Ti] Título:Selection, Realized Heritability, and Fitness Cost Associated With Dimethoate Resistance in a Field Population of Culex quinquefasciatus (Diptera: Culicidae).
[So] Source:J Econ Entomol;110(3):1252-1258, 2017 Jun 01.
[Is] ISSN:1938-291X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Mosquitoes are known to be vectors of numerous diseases leading to human morbidity and mortality at large scale in the world. Insecticide resistance has become a serious concern in controlling the insect vectors of public health importance. Dimethoate is an organophosphate insecticide used to control different insect pests including mosquitoes. Biological parameters of susceptible, unselected, and dimethoate-selected strains of Culex quinquefasciatus Say were studied in the laboratory to recognize resistance development potential and associated fitness cost. The dimethoate-selected strain showed 66.48-fold resistance to dimethoate compared with the susceptible strain after three continuous selections of generations. Realized heritability estimates of dimethoate resistance in Cx. quinquefasciatus yielded a value of 0.19. In dimethoate-selected strain, the biological traits including larval weight, survival from first instar to pupae, fecundity, number of next-generation larvae, relative fitness, net reproductive rate, intrinsic rate of natural increase, and biotic potential were significantly reduced as compared with the unselected strain. However, adult longevity, mean relative growth rate, weight of egg raft, female ratio, pupal duration, and emergence rate of the dimethoate-selected strain did not differ significantly compared with that of the unselected strain. This study provides useful information to devise retrospective management strategy for dimethoate resistance in Cx. quinquefasciatus.
[Mh] Termos MeSH primário: Culex/genética
Dimetoato/farmacologia
Aptidão Genética
Hereditariedade
Resistência a Inseticidas
Inseticidas/farmacologia
Seleção Genética
[Mh] Termos MeSH secundário: Animais
Culex/efeitos dos fármacos
Culex/crescimento & desenvolvimento
Feminino
Larva/efeitos dos fármacos
Larva/genética
Larva/crescimento & desenvolvimento
Masculino
Pupa/efeitos dos fármacos
Pupa/genética
Pupa/crescimento & desenvolvimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170324
[St] Status:MEDLINE
[do] DOI:10.1093/jee/tox049


  5 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28260687
[Au] Autor:Jegede OO; Owojori OJ; Römbke J
[Ad] Endereço:Department of Zoology, Obafemi Awolowo University, Ile-Ife, Nigeria; Toxicology Centre/Department of Soil Science, University of Saskatchewan, Saskatoon, SK, Canada. Electronic address: ooj692@mail.usask.ca.
[Ti] Título:Temperature influences the toxicity of deltamethrin, chlorpyrifos and dimethoate to the predatory mite Hypoaspis aculeifer (Acari) and the springtail Folsomia candida (Collembola).
[So] Source:Ecotoxicol Environ Saf;140:214-221, 2017 Jun.
[Is] ISSN:1090-2414
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:In order to assess the influence of temperature on pesticide toxicity to soil fauna, specimens of the predatory mite Hypoaspis aculeifer and the springtail Folsomia candida were exposed in artificial soil spiked with different concentrations of three pesticides (dimethoate, chlorpyrifos and deltamethrin) at 20°C vs 28°C for the mites and 20°C vs 26°C for the springtails. All tests were carried out according to OECD guidelines. In the mite tests, the toxic effects of dimethoate and chlorpyrifos on survival was about two orders of magnitude more at 28°C than at 20°C. Mite reproduction decreased in the tests with chlorpyrifos and deltamethrin by about four to five orders of magnitude at 28°C than at 20°C. (EC50 ° =1.42 and 2.52mg/kg vs EC50 ° =6.18 and 10.09mg/kg) In the collembolan tests, the toxicity of dimethoate on survival was higher at 26°C than at 20°C (LC50 ° =0.17mg/kg vs LC50 ° =0.36mg/kg), while the opposite was detected for deltamethrin (LC50 ° =11.27mg/kg vs LC50 ° =6.84mg/kg). No difference was found in the test with chlorpyrifos. Effects of dimethoate and chlorpyrifos on reproduction were higher at 26°C than at 20°C (EC50 ° =0.11 and 0.018mg/kg vs EC50 ° =0.29 and 0.031mg/kg respectively), but in the case of deltamethrin the opposite was observed (EC50 ° =12.85mg/kg vs EC50 ° =2.77mg/kg). A preliminary risk assessment of the three pesticides at the two temperature regimes based on the Toxicity Exposure Ratio (TER) approach of the European Union, shows that in general there are few different outcomes when comparing data gained at different temperatures. However, in the light of the few comparisons made data gained in temperate regions should be used with caution in the tropics.
[Mh] Termos MeSH primário: Artrópodes/efeitos dos fármacos
Clorpirifos/toxicidade
Dimetoato/toxicidade
Inseticidas/toxicidade
Nitrilos/toxicidade
Piretrinas/toxicidade
[Mh] Termos MeSH secundário: Animais
Ácaros/efeitos dos fármacos
Reprodução/efeitos dos fármacos
Medição de Risco
Solo/química
Poluentes do Solo/toxicidade
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Insecticides); 0 (Nitriles); 0 (Pyrethrins); 0 (Soil); 0 (Soil Pollutants); 2JTS8R821G (decamethrin); JCS58I644W (Chlorpyrifos); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170307
[St] Status:MEDLINE


  6 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28211333
[Au] Autor:Kiljanek T; Niewiadowska A; Gawel M; Semeniuk S; Borzecka M; Posyniak A; Pohorecka K
[Ad] Endereço:Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland. Electronic address: tomasz.kiljanek@piwet.pulawy.pl.
[Ti] Título:Multiple pesticide residues in live and poisoned honeybees - Preliminary exposure assessment.
[So] Source:Chemosphere;175:36-44, 2017 May.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Study combines data about the exposure of honeybees to pesticides from plant protection products and veterinary medicinal products. Residues of 200 pesticide and pesticide metabolites in 343 live and 74 poisoned honeybee samples, obtained during the years of 2014-2015, were determined by LC-MS/MS and GC-MS/MS. In 44% of live honeybee 48 different pesticide residues were found, mainly amitraz metabolites (DMF, DMPF) and chlorpyrifos. In 98% of poisoned honeybee 57 pesticides and metabolites were detected, mainly chlorpyrifos, dimethoate and clothianidin. In total 84 different pesticides were detected both in live and poisoned honeybees, they indicate 30 various modes of action. Differences between mean number of pesticide residues detected in live and poisoned honeybees clearly indicate the impact of multiple pesticides on honeybee health. Possible impact of systemic fungicides on the health of honeybees was studied. Applicability of hazard quotient counted as ratio between concentration of pesticides in honeybees and lethal dose in the interpretation whether detected concentration indicates acute toxic effects was shown.
[Mh] Termos MeSH primário: Abelhas/química
Abelhas/efeitos dos fármacos
Exposição Ambiental/análise
Resíduos de Praguicidas/análise
[Mh] Termos MeSH secundário: Animais
Clorpirifos/análise
Cromatografia Líquida
Dimetoato/análise
Guanidinas/análise
Neonicotinoides
Resíduos de Praguicidas/toxicidade
Praguicidas/análise
Praguicidas/toxicidade
Espectrometria de Massas em Tandem
Tiazóis/análise
Toluidinas/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Guanidines); 0 (Neonicotinoids); 0 (Pesticide Residues); 0 (Pesticides); 0 (Thiazoles); 0 (Toluidines); 2V9906ABKQ (clothianidin); 33IAH5017S (amitraz); JCS58I644W (Chlorpyrifos); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170218
[St] Status:MEDLINE


  7 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28159279
[Au] Autor:Hsu CW; Lin ZY; Chan TY; Chiu TC; Hu CC
[Ad] Endereço:Department of Applied Science, National Taitung University, Taitung, Taiwan, ROC. Electronic address: chunweihsu77@gmail.com.
[Ti] Título:Oxidized multiwalled carbon nanotubes decorated with silver nanoparticles for fluorometric detection of dimethoate.
[So] Source:Food Chem;224:353-358, 2017 Jun 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A novel method for the detection of dimethoate based on the peroxidase-like activity of silver-nanoparticles-modified oxidized multiwalled carbon nanotubes (AgNPs/oxMWCNTs) has been developed. The synthesized AgNPs/oxMWCNTs showed excellent peroxidease-like catalytic activity in hydrogen peroxide-Amplex red (AR) system (AR is oxidized to resorufinat, with the resorufin fluorescence at 584nm being used to monitor the catalytic activity). After dimethoate was added to AgNPs/oxMWCNTs, the interaction between dimethoate and the AgNPs inhibited the catalytic activity of AgNPs/oxMWCNTs. The decrease in fluorescence was used for the detection of dimethoate in the range of 0.01-0.35µgmL (R =0.998) with a detection limit of 0.003µgmL (signal/noise=3). This method exhibited good selectivity for the detection of dimethoate even in the presence of high concentration of other pesticides. Consequently, the method was applied to measure the concentration of dimethoate residue in lake water and fruit, thus obtaining satisfactory results.
[Mh] Termos MeSH primário: Dimetoato/análise
Nanopartículas Metálicas/química
Nanotubos de Carbono/química
Prata/química
[Mh] Termos MeSH secundário: Fluorometria
Análise de Alimentos
Frutas/química
Peróxido de Hidrogênio/metabolismo
Lagos/química
Limite de Detecção
Praguicidas/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Nanotubes, Carbon); 0 (Pesticides); 3M4G523W1G (Silver); BBX060AN9V (Hydrogen Peroxide); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170205
[St] Status:MEDLINE


  8 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28116643
[Au] Autor:Chen XD; Gill TA; Pelz-Stelinski KS; Stelinski LL
[Ad] Endereço:Entomology and Nematology Department, University of Florida, Citrus Research and Education Center, 700 Experiment Station Rd, Lake Alfred, FL, 33850, USA. xuedongchen@ymail.com.
[Ti] Título:Risk assessment of various insecticides used for management of Asian citrus psyllid, Diaphorina citri in Florida citrus, against honey bee, Apis mellifera.
[So] Source:Ecotoxicology;26(3):351-359, 2017 Apr.
[Is] ISSN:1573-3017
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae), is a major pest of citrus trees worldwide. A wide variety of insecticides are used to manage D. citri populations within citrus groves in Florida. However, in areas shared by citrus growers and beekeepers the use of insecticides may increase the risks of Apis mellifera  L. (Hymenoptera: Apidae) loss and contaminated honey. The objective of this research was to determine the environmental toxicity of insecticides, spanning five different modes of action used to control D. citri, to A. mellifera. The insecticides investigated were imidacloprid, fenpropathrin, dimethoate, spinetoram and diflubenzuron. In laboratory experiments, LD values were determined and ranged from 0.10 to 0.53 ng/µl for imidacloprid, fenpropathrin, dimethoate and spinetoram. LD values for diflubenzuron were >1000 ng/µl. Also, a hazard quotient was determined and ranged from 1130.43 to 10893.27 for imidacloprid, fenpropathrin, dimethoate, and spinetoram. This quotient was <0.447 for diflubenzuron. In field experiments, residual activity of fenpropathrin and dimethoate applied to citrus caused significant mortality of A. mellifera 3 and 7 days after application. Spinetoram and imidacloprid were moderately toxic to A. mellifera at the recommended rates for D. citri. Diflubenzuron was not toxic to A. mellifera in the field as compared with untreated control plots. Phenoloxidase (PO) activity of A. mellifera was higher than in untreated controls when A. mellifera were exposed to 14 days old residues. The results indicate that diflubenzuron may be safe to apply in citrus when A. mellifera are foraging, while most insecticides used for management of D. citri in citrus are likely hazardous under various exposure scenarios.
[Mh] Termos MeSH primário: Abelhas/fisiologia
Hemípteros/fisiologia
Controle de Insetos/métodos
Inseticidas/toxicidade
[Mh] Termos MeSH secundário: Animais
Citrus
Diflubenzuron/toxicidade
Dimetoato/toxicidade
Ecotoxicologia
Imidazóis/toxicidade
Macrolídeos/toxicidade
Neonicotinoides
Nitrocompostos/toxicidade
Piretrinas/toxicidade
Medição de Risco
Testes de Toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Imidazoles); 0 (Insecticides); 0 (Macrolides); 0 (Neonicotinoids); 0 (Nitro Compounds); 0 (Pyrethrins); 3BN7M937V8 (imidacloprid); 87BH96P0MX (fenpropathrin); J76U6ZSI8D (Diflubenzuron); W6U08B045O (Dimethoate); YGZ1037ELN (spinetoram)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170125
[St] Status:MEDLINE
[do] DOI:10.1007/s10646-017-1768-5


  9 / 682 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27816289
[Au] Autor:Narra MR
[Ad] Endereço:Department of Zoology, Osmania University, Hyderabad, Telangana, 500 007, India. Electronic address: narramadhusudan@gmail.com.
[Ti] Título:Haematological and immune upshots in Clarias batrachus exposed to dimethoate and defying response of dietary ascorbic acid.
[So] Source:Chemosphere;168:988-995, 2017 Feb.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Dimethoate (DM) is an organophosphate insecticide used worldwide in agriculture, household practices. It has resulted in a series of environmental and toxicological impacts on non-target aquatic organisms. The present study investigated the potential ameliorative effects of dietary ascorbic acid (AA) against dimethoate toxicity in the haematological and immune parameters in Clarias batrachus. The experiment included group A (basal diet), group B (basal diet with 1.245 mg L DM) and group C (200 mg kg AA with 1.245 mg L DM) were fed for 8 weeks. Samples were collected at the end of every week in each group and estimated haematological profile (red blood cell count, haemoglobin concentration, haematocrit %, albumin and globulin levels), erythrocyte indices (mean corpuscular volume, mean corpuscular haemoglobin, and mean corpuscular haemoglobin concentration), biochemical parameters (AA levels in blood and liver, total proteins, glucose, serum triglycerides, creatinine levels and glutamic oxaloacetate, glutamic pyruvate transaminase (GOT, GPT)) and immune responses (white blood cell count, serum IgM levels and activities of nitroblue tetrazolium, lysozyme and peroxidase) of the fish. Fish fed with ascorbic acid, showed red blood cell, haemoglobin, haematocrit, erythrocyte indices, albumin, globulin and serum triglycerides, creatinine, plasma total proteins, glucose levels are not differed (≤10%) from control. Likewise, ascorbic acid maintains optimal levels in activities of GOT, GPT, nitroblue tetrazolium, lysozyme and peroxidase, white blood cells and serum IgM levels. Further studies are needed to ascertain how ascorbic acid improves the innate and humoral immune system of the fish and the mechanisms involved.
[Mh] Termos MeSH primário: Ácido Ascórbico/farmacologia
Dimetoato/toxicidade
Inseticidas/toxicidade
[Mh] Termos MeSH secundário: Animais
Peixes-Gato/sangue
Peixes-Gato/metabolismo
Dieta/veterinária
Testes Hematológicos
Imunoglobulina M/sangue
Fígado/metabolismo
Muramidase/sangue
Peroxidase/sangue
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Immunoglobulin M); 0 (Insecticides); EC 1.11.1.7 (Peroxidase); EC 3.2.1.17 (Muramidase); PQ6CK8PD0R (Ascorbic Acid); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161107
[St] Status:MEDLINE


  10 / 682 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27714546
[Au] Autor:Albendín G; Arellano JM; Mánuel-Vez MP; Sarasquete C; Arufe MI
[Ad] Endereço:Toxicology Laboratory, Faculty of Marine and Environmental Sciences, University of Cádiz, Polígono Río San Pedro s/n, 11510, Puerto Real, Cádiz, Spain. gemma.albendin@uca.es.
[Ti] Título:Characterization and in vitro sensitivity of cholinesterases of gilthead seabream (Sparus aurata) to organophosphate pesticides.
[So] Source:Fish Physiol Biochem;43(2):455-464, 2017 Apr.
[Is] ISSN:1573-5168
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The characterization of cholinesterase activity in brain and muscle of gilthead seabream was carried out using four specific substrates and three selective inhibitors. In addition, K and V were calculated from the Michaelis-Menten equation for ASCh and BSCh substrates. Finally, the in vitro sensitivity of brain and muscle cholinesterases to three organophosphates (OPs) was also investigated by estimating inhibition kinetics. The results indicate that AChE is the enzyme present in the brain, whereas in muscle, a typical AChE form is present along with an atypical form of BChE. Very low ChE activity was found in plasma with all substrates used. The inhibitory potency of the studied OPs on brain and muscle AChEs based on bimolecular inhibition constants (k ) was: omethoate < dichlorvos < azinphosmethyl-oxon. Furthermore, muscle BChE was found to be several orders of magnitude (from 2 to 4) more sensitive than brain and muscle AChE inhibition by dichlorvos and omethoate.
[Mh] Termos MeSH primário: Azinfos-Metil/análogos & derivados
Inibidores da Colinesterase/toxicidade
Colinesterases/metabolismo
Diclorvós/toxicidade
Dimetoato/análogos & derivados
Proteínas de Peixes/metabolismo
Inseticidas/toxicidade
[Mh] Termos MeSH secundário: Animais
Azinfos-Metil/toxicidade
Biomarcadores/sangue
Biomarcadores/metabolismo
Encéfalo/efeitos dos fármacos
Encéfalo/metabolismo
Colinesterases/sangue
Dimetoato/toxicidade
Proteínas de Peixes/antagonistas & inibidores
Proteínas de Peixes/sangue
Músculos/efeitos dos fármacos
Músculos/metabolismo
Dourada/sangue
Dourada/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomarkers); 0 (Cholinesterase Inhibitors); 0 (Fish Proteins); 0 (Insecticides); 265842EWUV (Azinphosmethyl); 28U28EWE79 (dimethoxon); 7U370BPS14 (Dichlorvos); 961-22-8 (azinphosmethyl oxon); EC 3.1.1.8 (Cholinesterases); W6U08B045O (Dimethoate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171020
[Lr] Data última revisão:
171020
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161008
[St] Status:MEDLINE
[do] DOI:10.1007/s10695-016-0299-y



página 1 de 69 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde