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[PMID]:29188669
[Au] Autor:Huang WQ; Li LH; Li Z; Hong SJ
[Ad] Endereço:School of Forensic Medicine, Kunming Medical University, Kunming 650500, China.
[Ti] Título:[Forensic Analysis of 20 Dead Cases Related to Heroin Abuse].
[So] Source:Fa Yi Xue Za Zhi;32(4):266-268, 2016 Aug.
[Is] ISSN:1004-5619
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:OBJECTIVES: To perform retrospective analysis on 20 dead cases related to heroin abuse, and to provide references for the forensic assessment of correlative cases. METHODS: Among 20 dead cases related to heroin abuse, general situation, using method of drug, cause of death and result of forensic examination were analyzed by statistical analysis for summarizing the cause of death and pathologic changes. RESULTS: The dead were mostly young adults, with more male than female. The results of histopathological examinations showed non-specific pathological changes. There were four leading causes of death, including acute poisoning of heroin abuse or leakage (13 cases, 65%), concurrent diseases caused by heroin abuse (3 cases, 15%), inspiratory asphyxia caused by taking heroin (2 cases, 10%), and heroin withdrawal syndrome (2 cases, 10%). CONCLUSIONS: The forensic identification on dead related to heroin abuse must base on the comprehensive autopsy, and combine with the qualitative and quantitative analysis of heroin and its metabolites in death and the case information, as well as the scene investigation.
[Mh] Termos MeSH primário: Overdose de Drogas/diagnóstico
Heroína/envenenamento
[Mh] Termos MeSH secundário: Adulto
Autopsia
Causas de Morte
Feminino
Patologia Legal
Toxicologia Forense
Seres Humanos
Masculino
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
70D95007SX (Heroin)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.3969/j.issn.1004-5619.2016.04.008


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[PMID]:28448905
[Au] Autor:Bluthenthal RN; Wenger L; Chu D; Bourgois P; Kral AH
[Ad] Endereço:Department of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, 2001 N. Soto Street, Los Angeles, CA, 90033, USA. Electronic address: rbluthen@usc.edu.
[Ti] Título:Drug use generations and patterns of injection drug use: Birth cohort differences among people who inject drugs in Los Angeles and San Francisco, California.
[So] Source:Drug Alcohol Depend;175:210-218, 2017 06 01.
[Is] ISSN:1879-0046
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: A robust literature documents generational trends in drug use. We examined the implications of changing national drug use patterns on drug injection histories of diverse people who inject drugs (PWID). METHODS: Drug use histories were collected from 776 active PWID in 2011-13. Using descriptive statistics, we examine drug use initiation by year and birth cohort (BC) differences in drug first injected. A multivariate linear regression model of time to injection initiation ([TTII] (year of first injection minus year of first illicit drug use) was developed to explore BC differences. RESULTS: The first drug injected by BC changed in tandem with national drug use trends with heroin declining from 77% for the pre-1960's BC to 58% for the 1960's BC before increasing to 71% for the 1990's BC. Multivariate linear regression modeling found that shorter TTII was associated with the 1980's/1990's BC (-3.50 years; 95% Confidence Interval [CI]=-0.79, -6.21) as compared to the 1970's BC. Longer TTII was associated with being female (1.65 years; 95% CI=0.40, 2.90), African American (1.69 years; 95% CI=0.43, 2.95), any substance use treatment prior to injection (4.22 years; 95% CI=2.65, 5.79), and prior non-injection use of drug that was first injected (3.29 years; 95% CI=2.19, 4.40). CONCLUSION: National drug trends appear to influence injection drug use patterns. The prescription opiate drug era is associated with shorter TTII. Culturally competent, demographically and generationally-targeted prevention strategies to combat transitions to drug injection are needed to prevent or shorten upstream increases in risky drug use practices on a national level.
[Mh] Termos MeSH primário: Fatores Etários
Abuso de Substâncias por Via Intravenosa/epidemiologia
Transtornos Relacionados ao Uso de Substâncias/epidemiologia
[Mh] Termos MeSH secundário: Adulto
Estudos de Coortes
Feminino
Heroína
Seres Humanos
Modelos Lineares
Los Angeles/epidemiologia
Masculino
Meia-Idade
Análise Multivariada
São Francisco/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
70D95007SX (Heroin)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180123
[Lr] Data última revisão:
180123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE


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[PMID]:27776247
[Au] Autor:Karakula SL; Weiss RD; Griffin ML; Borges AM; Bailey AJ; McHugh RK
[Ad] Endereço:Division of Alcohol and Drug Abuse, McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States. Electronic address: skarakula@harvard.mclean.edu.
[Ti] Título:Delay discounting in opioid use disorder: Differences between heroin and prescription opioid users.
[So] Source:Drug Alcohol Depend;169:68-72, 2016 12 01.
[Is] ISSN:1879-0046
[Cp] País de publicação:Ireland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Among those with opioid use disorder, heroin use is associated with poorer prognosis relative to use of prescription opioids alone. However, relatively little is known about distinguishing features between those who use heroin relative to those who use prescription opioids. In the present study we evaluated differences in delay discounting in those with opioid use disorder based on primary opioid of use. Delay discounting is associated with a range of negative outcomes and is an important therapeutic target in this population. METHODS: Treatment-seeking adults with opioid dependence completed self-report measures including past-month opioid use and the Monetary Choice Questionnaire (Kirby and Marakovic, 1996; Kirby et al., 1999), a measure of delay discounting. Participants were divided into two groups based on whether they used any heroin in the past 30days or only prescription opioids, and delay discounting scores were compared between the groups. Group differences in sociodemographic or clinical variables were included in the analysis as covariates. RESULTS: Results from a forward stepwise linear regression indicated that heroin use was associated with significantly higher delay discounting (B=-0.99, SE =0.34, t=-2.88, p=0.005), even when considering covariates. CONCLUSIONS: Adults with opioid dependence who exclusively used prescription opioids had lower delay discounting relative to those who used heroin. This finding contributes further to the literature suggesting that heroin use is associated with greater clinical severity among those with opioid use disorder.
[Mh] Termos MeSH primário: Analgésicos Opioides/efeitos adversos
Desvalorização pelo Atraso
Heroína/efeitos adversos
Transtornos Relacionados ao Uso de Opioides/psicologia
Uso Indevido de Medicamentos sob Prescrição/psicologia
[Mh] Termos MeSH secundário: Adulto
Estudos Transversais
Desvalorização pelo Atraso/efeitos dos fármacos
Desvalorização pelo Atraso/fisiologia
Feminino
Dependência de Heroína/diagnóstico
Dependência de Heroína/psicologia
Seres Humanos
Masculino
Meia-Idade
Transtornos Relacionados ao Uso de Opioides/diagnóstico
Uso Indevido de Medicamentos sob Prescrição/efeitos adversos
Autorrelato
Inquéritos e Questionários
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (Analgesics, Opioid); 70D95007SX (Heroin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:180122
[Lr] Data última revisão:
180122
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


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[PMID]:29190175
[Au] Autor:Pergolizzi JV; LeQuang JA; Taylor R; Raffa RB; NEMA Research Group
[Ad] Endereço:a NEMA Research, Inc ., Naples , FL , USA.
[Ti] Título:Going beyond prescription pain relievers to understand the opioid epidemic: the role of illicit fentanyl, new psychoactive substances, and street heroin.
[So] Source:Postgrad Med;130(1):1-8, 2018 Jan.
[Is] ISSN:1941-9260
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The opioid epidemic is associated with morbidity and mortality, and it has taken a vast toll on American society. While prescription opioid abuse is part of the opioid problem, it is by no means the entirety of it. Opioid abuse appears to have entered a technology-driven new world of clandestine labs all over the globe and many new synthetic analog, counterfeit, and adulterated drugs that arrive via the internet faster than the Drug Enforcement Administration (DEA) can catalog and outlaw them. To deal with opioid abuse, it must be recognized that it is more - far more - than a subset of chronic pain patients who become addicted. Indeed, to reduce the opioid epidemic to this population is to misunderstand it. The opioid epidemic involves illicit opioids, counterfeit opioids, new psychoactive substances, diverted opioids, and prescription opioids. The objective of this narrative review is to consider the roles of all substances that contribute to the opioid epidemic in America.
[Mh] Termos MeSH primário: Analgésicos Opioides/efeitos adversos
Epidemias
Fentanila/efeitos adversos
Heroína/efeitos adversos
Transtornos Relacionados ao Uso de Opioides/epidemiologia
Psicotrópicos/efeitos adversos
[Mh] Termos MeSH secundário: Seres Humanos
Drogas Ilícitas/efeitos adversos
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Analgesics, Opioid); 0 (Psychotropic Drugs); 0 (Street Drugs); 70D95007SX (Heroin); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180103
[Lr] Data última revisão:
180103
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1080/00325481.2018.1407618


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[PMID]:28450608
[Au] Autor:O'Neil K
[Ti] Título:S&T Policy Forum examines evolving opioid epidemic.
[So] Source:Science;356(6336):390, 2017 Apr 28.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Overdose de Drogas/epidemiologia
Epidemias
Dependência de Heroína/epidemiologia
Transtornos Relacionados ao Uso de Opioides/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Overdose de Drogas/tratamento farmacológico
Heroína/administração & dosagem
Heroína/efeitos adversos
Dependência de Heroína/tratamento farmacológico
Seres Humanos
Naloxona/administração & dosagem
Naloxona/uso terapêutico
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Estados Unidos/epidemiologia
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
36B82AMQ7N (Naloxone); 70D95007SX (Heroin)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171219
[Lr] Data última revisão:
171219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE
[do] DOI:10.1126/science.356.6336.390-a


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[PMID]:28859052
[Au] Autor:O'Donnell JK; Gladden RM; Seth P
[Ad] Endereço:Division of Unintentional Injury Prevention, National Center for Injury Prevention and Control, CDC.
[Ti] Título:Trends in Deaths Involving Heroin and Synthetic Opioids Excluding Methadone, and Law Enforcement Drug Product Reports, by Census Region - United States, 2006-2015.
[So] Source:MMWR Morb Mortal Wkly Rep;66(34):897-903, 2017 Sep 01.
[Is] ISSN:1545-861X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Opioid overdose deaths quadrupled from 8,050 in 1999 to 33,091 in 2015 and accounted for 63% of drug overdose deaths in the United States in 2015. During 2010-2015, heroin overdose deaths quadrupled from 3,036 to 12,989 (1). Sharp increases in the supply of heroin and illicitly manufactured fentanyl (IMF) are likely contributing to increased deaths (2-6). CDC examined trends in unintentional and undetermined deaths involving heroin or synthetic opioids excluding methadone (i.e., synthetic opioids)* by the four U.S. Census regions during 2006-2015. Drug exhibits (i.e., drug products) obtained by law enforcement and reported to the Drug Enforcement Administration's (DEA's) National Forensic Laboratory Information System (NFLIS) that tested positive for heroin or fentanyl (i.e., drug reports) also were examined. All U.S. Census regions experienced substantial increases in deaths involving heroin from 2006 to 2015. Since 2010, the South and West experienced increases in heroin drug reports, whereas the Northeast and Midwest experienced steady increases during 2006-2015. In the Northeast, Midwest, and South, deaths involving synthetic opioids and fentanyl drug reports increased considerably after 2013. These broad changes in the U.S. illicit drug market highlight the urgent need to track illicit drugs and enhance public health interventions targeting persons using or at high risk for using heroin or IMF.
[Mh] Termos MeSH primário: Analgésicos Opioides/envenenamento
Drogas Desenhadas/envenenamento
Overdose de Drogas/mortalidade
Fentanila/envenenamento
Heroína/envenenamento
Drogas Ilícitas/legislação & jurisprudência
Drogas Ilícitas/envenenamento
[Mh] Termos MeSH secundário: Censos
Seres Humanos
Aplicação da Lei
Mortalidade/tendências
Estados Unidos/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid); 0 (Designer Drugs); 0 (Street Drugs); 70D95007SX (Heroin); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE
[do] DOI:10.15585/mmwr.mm6634a2


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[PMID]:28759635
[Au] Autor:Garami J; Haber P; Myers CE; Allen MT; Misiak B; Frydecka D; Moustafa AA
[Ad] Endereço:School of Social Sciences and Psychology, Western Sydney University, Sydney, New South Wales, Australia.
[Ti] Título:Intolerance of uncertainty in opioid dependency - Relationship with trait anxiety and impulsivity.
[So] Source:PLoS One;12(7):e0181955, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Intolerance of uncertainty (IU) is the tendency to interpret ambiguous situations as threatening and having negative consequences, resulting in feelings of distress and anxiety. IU has been linked to a number of anxiety disorders, and anxiety felt in the face of uncertainty may result in maladaptive behaviors such as impulsive decision making. Although there is strong evidence that anxiety and impulsivity are risk factors for addiction, there is a paucity of research examining the role of IU in this disorder. The rate of opioid addiction, in particular, has been rising steadily in recent years, which necessitates deeper understanding of risk factors in order to develop effective prevention and treatment methods. The current study tested for the first time whether opioid-dependent adults are less tolerant of uncertainty compared to a healthy comparison group. Opioid dependent patients undergoing methadone maintenance therapy (n = 114) and healthy comparisons (n = 69) completed the following scales: Intolerance of Uncertainty Scale, the Barrett Impulsivity Scale, and the State Trait Anxiety Inventory. Analysis revealed that these measures were positively correlated with each other and that opioid-dependent patients had significantly higher IU scores. Regression analysis revealed that anxiety mediated the relationship between IU and impulsivity. Hierarchical moderation regression found an interaction between addiction status and impulsivity on IU scores in that the relationship between these variables was only observed in the patient group. Findings suggest that IU is a feature of addiction but does not necessarily play a unique role. Further research is needed to explore the complex relationship between traits and how they may contribute to the development and maintenance of addiction.
[Mh] Termos MeSH primário: Ansiedade/psicologia
Comportamento Impulsivo
Transtornos Relacionados ao Uso de Opioides/psicologia
[Mh] Termos MeSH secundário: Adulto
Analgésicos Opioides/efeitos adversos
Ansiedade/complicações
Estudos de Casos e Controles
Tomada de Decisões
Feminino
Heroína/efeitos adversos
Seres Humanos
Masculino
Metadona/uso terapêutico
Meia-Idade
Transtornos Relacionados ao Uso de Opioides/complicações
Inventário de Personalidade
Escalas de Graduação Psiquiátrica
Análise de Regressão
Fatores de Risco
Incerteza
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Analgesics, Opioid); 70D95007SX (Heroin); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170801
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0181955


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[PMID]:28586356
[Au] Autor:Zhou K; Wang D; Li H; Wei X; Yin J; Liang P; Kou L; Hao M; You L; Li X; Zhuang G
[Ad] Endereço:Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.
[Ti] Título:Bidirectional relationships between retention and health-related quality of life in Chinese mainland patients receiving methadone maintenance treatment.
[So] Source:PLoS One;12(6):e0179009, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study aimed to explore the bidirectional relationships between retention and health-related quality of life (HRQoL) in patients from mainland China receiving methadone maintenance treatment (MMT). This prospective cohort study recruited 1,212 eligible MMT patients from the two largest MMT clinics (one privately and another publicly funded) in Xi'an. This study started in March 2012 with a 2-year follow-up until March 2014. Retention was assessed by repeated terminations, past treatment duration, premature terminations, and follow-up treatment duration. HRQoL was evaluated using the Chinese (simple) short-form 36 health survey version 2 (SF-36v2) and the quality of life scale for drug addicts (QOL-DAv2.0). Linear and Cox regression analyses were used to explore relationships between retention and HRQoL. A general linear model was used to further examine the global effect of past treatment duration on HRQoL. Multivariate analyses showed that repeated terminations had no significant impact on HRQoL scores in MMT patients; however, past treatment time (year) influenced the SF-36v2PCS (P = 0.004): treatment for ≥4 years showed a lower SF-36v2PCS score (regression coefficient: -2.39; 95% confidence interval [CI]: -3.80, -0.97; P = 0.001) than treatment for <1 year. In addition, patients with an SF-36v2PCS score > 49 (hazard ratio: 0.83; 95% CI: 0.69, 0.98; P = 0.03) were 17% less likely to terminate MMT than those with scores of ≤49. In conclusion, retention and HRQoL tended to have a bidirectional relationship, which should be considered in the development of retention and health-management programs for patients with MMT.
[Mh] Termos MeSH primário: Usuários de Drogas
Dependência de Heroína/tratamento farmacológico
Metadona/uso terapêutico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Criança
China
Feminino
Heroína/toxicidade
Dependência de Heroína/patologia
Dependência de Heroína/urina
Seres Humanos
Masculino
Metadona/efeitos adversos
Metadona/urina
Meia-Idade
Análise Multivariada
Tratamento de Substituição de Opiáceos/efeitos adversos
Modelos de Riscos Proporcionais
Qualidade de Vida
Centros de Tratamento de Abuso de Substâncias
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
70D95007SX (Heroin); UC6VBE7V1Z (Methadone)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170919
[Lr] Data última revisão:
170919
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179009


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[PMID]:28585663
[Au] Autor:Worley J
[Ti] Título:A Primer on Heroin and Fentanyl.
[So] Source:J Psychosoc Nurs Ment Health Serv;55(6):16-20, 2017 Jun 01.
[Is] ISSN:0279-3695
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Heroin and fentanyl use have reached epidemic proportions in the United States and are now blamed for the majority of drug-related overdose deaths. Both drugs are produced primarily in South America and Asia and enter the United States illegally. One result of smoking or injecting heroin or fentanyl is the development of a substance use disorder (SUD), which causes changes in brain chemistry and function. These changes result in negative behaviors and an inability to stop use. Yet, treatments are available and recovery is possible. Nurses have the potential to impact the heroin and fentanyl epidemic through developing therapeutic relationships with patients who are at risk or already have a SUD. Strategies for effective communication include maintaining a supportive, nonjudgmental attitude and incorporating motivational interviewing. All patients should be screened for opioid use and referred for treatment if indicated. It is important for nurses to be knowledgeable about heroin and fentanyl and available treatments. [Journal of Psychosocial Nursing and Mental Health Services, 55(6), 16-20.].
[Mh] Termos MeSH primário: Overdose de Drogas/epidemiologia
Fentanila/envenenamento
Heroína/envenenamento
[Mh] Termos MeSH secundário: Overdose de Drogas/história
História do Século XIX
História do Século XX
História do Século XXI
Seres Humanos
Relações Enfermeiro-Paciente
Transtornos Relacionados ao Uso de Opioides/tratamento farmacológico
Transtornos Relacionados ao Uso de Opioides/epidemiologia
Transtornos Relacionados ao Uso de Opioides/enfermagem
Transtornos Relacionados ao Uso de Substâncias/história
Estados Unidos
[Pt] Tipo de publicação:HISTORICAL ARTICLE; JOURNAL ARTICLE
[Nm] Nome de substância:
70D95007SX (Heroin); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170717
[Lr] Data última revisão:
170717
[Sb] Subgrupo de revista:IM; N
[Da] Data de entrada para processamento:170607
[St] Status:MEDLINE
[do] DOI:10.3928/02793695-20170519-02


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[PMID]:28506507
[Au] Autor:Moore PQ; Weber J; Cina S; Aks S
[Ad] Endereço:1900 W Polk St., 10th Floor, Administration Building, Chicago, IL 60612, USA. Electronic address: moore.quincy@gmail.com.
[Ti] Título:Syndrome surveillance of fentanyl-laced heroin outbreaks: Utilization of EMS, Medical Examiner and Poison Center databases.
[So] Source:Am J Emerg Med;35(11):1706-1708, 2017 Nov.
[Is] ISSN:1532-8171
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Describe surveillance data from three existing surveillance systems during an unexpected fentanyl outbreak in a large metropolitan area. METHODS: We performed a retrospective analysis of three data sets: Chicago Fire Department EMS, Cook County Medical Examiner, and Illinois Poison Center. Each included data from January 1, 2015 through December 31, 2015. EMS data included all EMS responses in Chicago, Illinois, for suspected opioid overdose in which naloxone was administered and EMS personnel documented other criteria indicative of opioid overdose. Medical Examiner data included all deaths in Cook County, Illinois, related to heroin, fentanyl or both. Illinois Poison Center data included all calls in Chicago, Illinois, related to fentanyl, heroin, and other prescription opioids. Descriptive statistics using Microsoft Excel® were used to analyze the data and create figures. RESULTS: We identified a spike in opioid-related EMS responses during an 11-day period from September 30-October 10, 2015. Medical Examiner data showed an increase in both fentanyl and mixed fentanyl/heroin related deaths during the months of September and October, 2015 (375% and 550% above the median, respectively.) Illinois Poison Center data showed no significant increase in heroin, fentanyl, or other opioid-related calls during September and October 2015. CONCLUSION: Our data suggests that EMS data is an effective real-time surveillance mechanism for changes in the rate of opioid overdoses. Medical Examiner's data was found to be valuable for confirmation of EMS surveillance data and identification of specific intoxicants. Poison Center data did not correlate with EMS or Medical Examiner data.
[Mh] Termos MeSH primário: Surtos de Doenças
Overdose de Drogas/epidemiologia
Fentanila/envenenamento
Heroína/envenenamento
Entorpecentes/envenenamento
[Mh] Termos MeSH secundário: Chicago/epidemiologia
Médicos Legistas
Estudos Transversais
Bases de Dados Factuais
Contaminação de Medicamentos
Overdose de Drogas/tratamento farmacológico
Overdose de Drogas/etiologia
Overdose de Drogas/mortalidade
Serviços Médicos de Emergência
Seres Humanos
Illinois/epidemiologia
Naloxona/uso terapêutico
Antagonistas de Entorpecentes/uso terapêutico
Centros de Controle de Intoxicações
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Narcotic Antagonists); 0 (Narcotics); 36B82AMQ7N (Naloxone); 70D95007SX (Heroin); UF599785JZ (Fentanyl)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170517
[St] Status:MEDLINE



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