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[PMID]:27077347
[Au] Autor:Wallace S; Nazroo J; Bécares L
[Ad] Endereço:All of the authors are with Centre on Dynamics of Ethnicity, University of Manchester, Manchester, Lancashire, UK.
[Ti] Título:Cumulative Effect of Racial Discrimination on the Mental Health of Ethnic Minorities in the United Kingdom.
[So] Source:Am J Public Health;106(7):1294-300, 2016 Jul.
[Is] ISSN:1541-0048
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: To examine the longitudinal association between cumulative exposure to racial discrimination and changes in the mental health of ethnic minority people. METHODS: We used data from 4 waves (2009-2013) of the UK Household Longitudinal Study, a longitudinal household panel survey of approximately 40 000 households, including an ethnic minority boost sample of approximately 4000 households. RESULTS: Ethnic minority people who reported exposure to racial discrimination at 1 time point had 12-Item Short Form Health Survey (SF-12) mental component scores 1.93 (95% confidence interval [CI] = -3.31, -0.56) points lower than did those who reported no exposure to racial discrimination, whereas those who had been exposed to 2 or more domains of racial discrimination, at 2 different time points, had SF-12 mental component scores 8.26 (95% CI = -13.33, -3.18) points lower than did those who reported no experiences of racial discrimination. Controlling for racial discrimination and other socioeconomic factors reduced ethnic inequalities in mental health. CONCLUSIONS: Cumulative exposure to racial discrimination has incremental negative long-term effects on the mental health of ethnic minority people in the United Kingdom. Studies that examine exposure to racial discrimination at 1 point in time may underestimate the contribution of racism to poor health.
[Mh] Termos MeSH primário: Grupos Étnicos/psicologia
Saúde Mental/etnologia
Grupos Minoritários/psicologia
Racismo/psicologia
[Mh] Termos MeSH secundário: Feminino
Nível de Saúde
Disparidades nos Níveis de Saúde
Hexitidina
Seres Humanos
Estudos Longitudinais
Masculino
Fatores Socioeconômicos
Estresse Psicológico/etnologia
Reino Unido
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
852A84Y8LS (Hexetidine)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170608
[Lr] Data última revisão:
170608
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:160415
[St] Status:MEDLINE
[do] DOI:10.2105/AJPH.2016.303121


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[PMID]:26750930
[Au] Autor:Deryabin PG; Galegov GA; Andronova VA; Botikov AG
[Ad] Endereço:D. I. Ivanovsky Research Institute of Virology, N. F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation, Moscow, Russia. pg_deryabin@mail.ru.
[Ti] Título:Analysis of Antiviral Properties of Hexoral In Vitro against Some Viruses that Cause Acute Respiratory Infections and Herpes.
[So] Source:Bull Exp Biol Med;160(3):353-6, 2016 Jan.
[Is] ISSN:1573-8221
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Antiviral properties of Hexoral (0.1% solution and 0.2% aerosol for local application) and its constituent hexetidine against viruses causing human respiratory tract infections and herpes virus were studied in vitro. It was found that non-cytotoxic concentrations of hexetidine (alone and as a component of Hexoral) attenuated infectious properties of highly virulent influenza virus A/H5N1, pandemic influenza virus A/H1N1pdm, respiratory syncytial virus, and herpes simplex virus type 1 after a short-term exposure (30 sec) by 100 or more times. It was found that hexidine mostly contributes to the virucidal effect of Hexoral.
[Mh] Termos MeSH primário: Antivirais/farmacologia
Hexitidina/farmacologia
[Mh] Termos MeSH secundário: Animais
Linhagem Celular
Cercopithecus aethiops
Cães
Seres Humanos
Vírus da Influenza A Subtipo H5N1/efeitos dos fármacos
Vírus da Influenza A Subtipo H5N1/patogenicidade
Infecções Respiratórias/prevenção & controle
Células Vero
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiviral Agents); 852A84Y8LS (Hexetidine)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160112
[St] Status:MEDLINE
[do] DOI:10.1007/s10517-016-3169-9


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[PMID]:26615573
[Au] Autor:Uygun-Can B; Kadir T; Gumru B
[Ad] Endereço:Department of Microbiology, Faculty of Dentistry, Marmara University, Istanbul, Turkey. Electronic address: drbanucan@gmail.com.
[Ti] Título:Effect of oral antiseptic agents on phospholipase and proteinase enzymes of Candida albicans.
[So] Source:Arch Oral Biol;62:20-7, 2016 Feb.
[Is] ISSN:1879-1506
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Candida-associated denture stomatitis is the most prevalent form of oral candida infections among the denture wearers. Generally, antiseptic oral rinses used in the treatment of these infections are considered as an adjunct or alternative antifungal treatment. Studies have suggested that the intraoral concentrations of antiseptics decrease substantially to the sub-therapeutic levels on account of the dynamics of the oral cavity. This condition yields the question about the minimum antiseptic concentration that effect the character or pathogenesis of Candida during treatment. The extracellular phospholipase and proteinase enzymes of Candida albicans are regarded to have a crucial role in the pathogenesis of human fungal infections. Therefore, the aim of this study was to investigate the effect of different sub-therapeutic concentrations of chlorhexidine gluconate, hexetidine and triclosan on the production of these enzymes by C. albicans strains isolated from 20 patients with denture stomatitis. METHODS: Phospholipase test was done by using Sabouraud dextrose agar with egg yolk, proteinase test was done by using bovine serum albumin agar. METHODS: Phospholipase test was done by using Sabouraud dextrose agar with egg yolk, proteinase test was done by using bovine serum albumin agar. RESULTS: Exoenzyme production of 20 strains which were brief exposured to sub-therapeutic concentrations of three antiseptic agents decreased significantly compared with the strains that were not exposured with antiseptic values (p<0.05). There was significant difference between the sub-therapeutic concentrations of each of three antiseptics (p<0.05). When the same concentrations of each antiseptic was compared, there were no significant differences between enzymatic activities (p>0.05). CONCLUSIONS: The results of this study show that sub-therapeutic levels of each antiseptic may modulate candidal exoenzyme production, consequently suppressing pathogenicity of C. albicans.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/farmacologia
Candida albicans/efeitos dos fármacos
Candida albicans/enzimologia
Peptídeo Hidrolases/biossíntese
Fosfolipases/biossíntese
[Mh] Termos MeSH secundário: Antifúngicos/farmacologia
Candida albicans/isolamento & purificação
Candidíase Bucal/microbiologia
Clorexidina/análogos & derivados
Clorexidina/farmacologia
Hexitidina/farmacologia
Seres Humanos
Testes de Sensibilidade Microbiana
Boca/microbiologia
Antissépticos Bucais/farmacologia
Estomatite sob Prótese/microbiologia
Triclosan/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Antifungal Agents); 0 (Mouthwashes); 4NM5039Y5X (Triclosan); 852A84Y8LS (Hexetidine); EC 3.1.- (Phospholipases); EC 3.4.- (Peptide Hydrolases); MOR84MUD8E (chlorhexidine gluconate); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:151130
[St] Status:MEDLINE


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[PMID]:25601200
[Au] Autor:Chevalier M; Sakarovitch C; Precheur I; Lamure J; Pouyssegur-Rougier V
[Ad] Endereço:Laboratory of Oral Health and Aging, Faculty of Dentistry, University Nice Sophia Antipolis , Nice , France.
[Ti] Título:Antiseptic mouthwashes could worsen xerostomia in patients taking polypharmacy.
[So] Source:Acta Odontol Scand;73(4):267-73, 2015 May.
[Is] ISSN:1502-3850
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS: This cross-sectional observational study included 120 hospitalized patients (60 middle-aged and 60 elderly patients), taking polypharmacy (≥4 drugs daily) and at risk of drug-induced xerostomia. Xerostomia was assessed by questioning participants. RESULTS: A total of 62.5% of patients complained of xerostomia. In the middle-aged group (mean age=44.0 (8.7) years; 35.0% women) xerostomia seemed independently associated to mouthwashes, at the limit of significance (OR=5.00, 95% CI=0.99-25.3, p=0.052). Active principles in mouthwashes were mainly quaternary ammonium compounds (91.9%). Mouthwashes may disturb the healthy balance of the biofilm moisturizing the oral mucosa. The biofilm contains mucins, salivary glycoproteins with oligosaccharides side chains able to sequester water and endogenous bacteria surrounded by a glycocalyx. Oral bacteria are fully susceptible to quaternary ammonium (chlorhexidine, hexetidine, cetylpyridinium chloride) and to other antiseptics used in mouthwashes, such as betain, resorcin, triclosan, essential oils and alcohol. However, caregivers currently recommend such dental plaque control products to patients suffering from xerostomia in order to reduce the risk of caries and periodontitis. CONCLUSION: This study is the first report that use of antiseptic mouthwashes for more than 2 weeks could worsen xerostomia in patients taking polypharmacy. Oral care protocols should avoid this iatrogenic practice, particularly when xerostomia alters the quality-of-life and worsens malnutrition.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/efeitos adversos
Antissépticos Bucais/efeitos adversos
Polimedicação
Xerostomia/induzido quimicamente
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Betaína/efeitos adversos
Biofilmes/efeitos dos fármacos
Cetilpiridínio/efeitos adversos
Clorexidina/efeitos adversos
Estudos Transversais
Cárie Dentária/prevenção & controle
Interações Medicamentosas
Etanol/efeitos adversos
Feminino
Hexitidina/efeitos adversos
Seres Humanos
Masculino
Meia-Idade
Boca/microbiologia
Óleos Voláteis/efeitos adversos
Periodontite/prevenção & controle
Resorcinóis/efeitos adversos
Triclosan/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Mouthwashes); 0 (Oils, Volatile); 0 (Resorcinols); 3K9958V90M (Ethanol); 3SCV180C9W (Betaine); 4NM5039Y5X (Triclosan); 852A84Y8LS (Hexetidine); CUB7JI0JV3 (Cetylpyridinium); R4KO0DY52L (Chlorhexidine); YUL4LO94HK (resorcinol)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150318
[Lr] Data última revisão:
150318
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:150121
[St] Status:MEDLINE
[do] DOI:10.3109/00016357.2014.923108


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[PMID]:22528675
[Au] Autor:Linke GR; Tarantino I; Bruderer T; Celeiro J; Warschkow R; Tarr PE; Müller-Stich BP; Zerz A
[Ad] Endereço:Department of General, Visceral, and Transplant Surgery, University of Heidelberg, Im Neuenheimer Feld 110, Heidelberg, Germany. gelinke@web.de
[Ti] Título:Transvaginal access for NOTES: a cohort study of microbiological colonization and contamination.
[So] Source:Endoscopy;44(7):684-9, 2012 Jul.
[Is] ISSN:1438-8812
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND STUDY AIMS: Animal data and limited clinical evidence suggest a low incidence of infection following transvaginal natural orifice transluminal endoscopic surgery (NOTES). However, a systematic microbiological evaluation has not yet been carried out. The aim of this prospective cohort study was to evaluate the extent of microbiological contamination of the peritoneal cavity caused by the transvaginal access for NOTES and the impact of preoperative vaginal disinfection on vaginal colonization. PATIENTS AND METHODS: Consecutive female patients with symptomatic cholecystolithiasis were offered either transvaginal rigid-hybrid cholecystectomy (tvCCE) or conventional laparoscopic cholecystectomy. Patients who opted for tvCCE were prospectively evaluated between February and June 2010. Disinfection in patients undergoing tvCCE included hexetidine tablets and octenidine applied vaginally. All patients received a single dose of perioperative cefuroxime. Swabs were obtained from the posterior fornix and the peritoneal cavity at different intervals. RESULTS: Of 32 patients, 27 (84 %) opted to undergo tvCCE. One patient (4 %; 95 % confidence interval [CI] 0.7 % - 18.3 %) had a positive bacterial culture in the Douglas pouch prior to transvaginal access compared with two patients (7 %; 95 %CI 2.1 % - 23.4 %) following colpotomy closure (P = 1.000). Vaginal disinfection significantly decreased vaginal bacterial load (P = 0.001) and bacterial growth in routine cultures (P < 0.001); in 16 patients (59 %; 95 %CI 40.7 % - 75.5 %) vaginal swabs were sterile after disinfection. No postoperative surgical site infections occurred (95 %CI 0 % - 12.5 %). CONCLUSIONS: In selected patients and following vaginal antisepsis, transvaginal access for NOTES is associated with microbiological contamination of the peritoneal cavity in a minority of patients, indicating a low risk of peritoneal contamination caused by the transvaginal access.
[Mh] Termos MeSH primário: Antibioticoprofilaxia/métodos
Carga Bacteriana/efeitos dos fármacos
Colecistectomia
Colpotomia/efeitos adversos
Endoscopia Gastrointestinal
Doenças Peritoneais
Complicações Pós-Operatórias
Vagina/microbiologia
[Mh] Termos MeSH secundário: Administração Intravaginal
Adulto
Antibacterianos/uso terapêutico
Anti-Infecciosos Locais/uso terapêutico
Cefuroxima/uso terapêutico
Colecistectomia/efeitos adversos
Colecistectomia/métodos
Colecistectomia Laparoscópica/métodos
Colecistolitíase/cirurgia
Colpotomia/métodos
Endoscopia Gastrointestinal/efeitos adversos
Endoscopia Gastrointestinal/métodos
Contaminação de Equipamentos/prevenção & controle
Feminino
Hexitidina/uso terapêutico
Seres Humanos
Meia-Idade
Doenças Peritoneais/etiologia
Doenças Peritoneais/microbiologia
Doenças Peritoneais/prevenção & controle
Complicações Pós-Operatórias/microbiologia
Complicações Pós-Operatórias/prevenção & controle
Estudos Prospectivos
Piridinas/uso terapêutico
Resultado do Tratamento
Vagina/cirurgia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Anti-Infective Agents, Local); 0 (Pyridines); 852A84Y8LS (Hexetidine); O1R9FJ93ED (Cefuroxime); OZE0372S5A (octenidine)
[Em] Mês de entrada:1211
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120425
[St] Status:MEDLINE
[do] DOI:10.1055/s-0032-1309390


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[PMID]:22361161
[Au] Autor:Jolivot PA; Dunyach-Remy C; Roussey A; Jalabert A; Mallié M; Hansel-Esteller S
[Ad] Endereço:Pharmacie Lapeyronie-Arnaud-de-Villeneuve, centre hospitalier régional universitaire de Montpellier, 191 avenue du Doyen-Gaston-Giraud, Montpellier, France. jolivotpa@aol.fr
[Ti] Título:[Assessment of in vitro activity and stability of antifungal suspensions for mouthrinses: to a reappraisal of empiric practices?].
[Ti] Título:Étude d'activité in vitro et de stabilité de suspensions antifongiques pour bain de bouche : vers une remise en question de pratiques empiriques ?.
[So] Source:Pathol Biol (Paris);60(6):362-8, 2012 Dec.
[Is] ISSN:1768-3114
[Cp] País de publicação:France
[La] Idioma:fre
[Ab] Resumo:Establishment of an effective prophylaxis against oral candidiasis by local treatment is essential for immunocompromised patients. The aim of the study is to assess effectiveness and stability of antifungal suspensions for mouthrinses. The assessed suspensions are compounded by one solvent among sterile water, spring water or sodium bicarbonate associated with amphotericin B (Fungizone®) or nystatine (Mycostatine®). Two others mixes are assessed: Mycostatine®-bicarbonate and Mycostatine®-Hextril®-bicarbonate as well as the two straight antifungal. In vitro activity is tested on five Candida species (C. albicans, C. glabrata, C. krusei, C. parapsilosis, C. tropicalis) after a five minutes contact between yeasts and the assessed suspension. A galenic study is realized during 3 days. Mixes associating a polyene with sodium bicarbonate have no effectiveness on Candida albicans, others mixes shows intermediate effectiveness (the percentage of yeast growth inhibition lies between 35% and 68%). Effectiveness results of Hextril®-based mixes are not explainable because of alcohol in its composition. Spring water-based mixes must be evicted due to microbiologic contaminations after 48hours. Mycostatine®-Hextril®-bicarbonate mix is not stable during 3 days. All those mouthrinses, poorly effective, excepted on C. glabrata, should be avoided. Straight Mycostatine® shows a good antifungal effectiveness excepted on C. krusei and its use should be recommended.
[Mh] Termos MeSH primário: Antifúngicos/administração & dosagem
Candidíase Bucal/tratamento farmacológico
[Mh] Termos MeSH secundário: Anfotericina B/administração & dosagem
Candida/efeitos dos fármacos
Candida albicans/efeitos dos fármacos
Candida glabrata/efeitos dos fármacos
Estabilidade de Medicamentos
Hexitidina
Seres Humanos
Antissépticos Bucais
Nistatina/administração & dosagem
Bicarbonato de Sódio/administração & dosagem
Suspensões
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antifungal Agents); 0 (Mouthwashes); 0 (Suspensions); 1400-61-9 (Nystatin); 7XU7A7DROE (Amphotericin B); 852A84Y8LS (Hexetidine); 8MDF5V39QO (Sodium Bicarbonate)
[Em] Mês de entrada:1305
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120225
[St] Status:MEDLINE


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[PMID]:22273822
[Au] Autor:Martin M; Winterfeld I; Kramme E; Ewert I; Sedemund-Adib B; Mattner F
[Ad] Endereço:Institut für Umweltmedizin und Krankenhaushygiene, Universitätsklinikum Freiburg, Breisacher Str. 115b, 79106, Freiburg, Deutschland. maria.martin@uniklinik-freiburg.de
[Ti] Título:[Outbreak of Burkholderia cepacia complex caused by contaminated alcohol-free mouthwash].
[Ti] Título:Ausbruch mit Burkholderia-cepacia-Komplex durch kontaminierte Mundspüllösung..
[So] Source:Anaesthesist;61(1):25-9, 2012 Jan.
[Is] ISSN:1432-055X
[Cp] País de publicação:Germany
[La] Idioma:ger
[Ab] Resumo:BACKGROUND: A total of three intensive care units (ICU) at a German university hospital were involved in an outbreak of Burkholderia cepacia complex (Bcc). METHODS: Patients with microbiological detection of Bcc were evaluated. Products used for mouth hygiene were microbiologically tested. The clonal identity of Bcc was proven by pulse-field gel electrophoresis (PFGE). RESULTS: On 3 ICUs 12 cases were identified whereby the first detection of Bcc was in respiratory specimens of 11 patients and 1 in a wound swab from the oral cavity. Of these patients six developed ventilator-associated pneumonia (VAP). Investigations revealed that five different batches of an alcohol-free mouthwash containing hexetidine were highly contaminated. Isolates of Bcc from patients and mouthwashes were genetically indistinguishable. A recall of the product was initiated. After elimination of the product from the ICUs no more cases were identified. CONCLUSIONS: The source of the outbreak was an intrinsically contaminated alcohol-free mouthwash. Detection of Bcc in specimens from ICU patients should lead to further investigations. Antiseptic oral care products are recommended for reducing the risk of VAP but they may be microbiologically contaminated and, in consequence, increase the risk. The safety of patient care products should be increased by stricter regulations.
[Mh] Termos MeSH primário: Infecções por Burkholderia/etiologia
Complexo Burkholderia cepacia
Infecção Hospitalar/etiologia
Contaminação de Medicamentos
Antissépticos Bucais
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Anti-Infecciosos Locais
Líquido da Lavagem Broncoalveolar/microbiologia
Infecções por Burkholderia/microbiologia
Infecção Hospitalar/microbiologia
Bases de Dados Factuais
Surtos de Doenças
Recall de Medicamento
Eletroforese em Gel de Campo Pulsado
Feminino
Hexitidina
Seres Humanos
Unidades de Terapia Intensiva
Masculino
Meia-Idade
Boca/microbiologia
Higiene Bucal
Pneumonia Associada à Ventilação Mecânica/etiologia
Pneumonia Associada à Ventilação Mecânica/microbiologia
Estudos Retrospectivos
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Mouthwashes); 852A84Y8LS (Hexetidine)
[Em] Mês de entrada:1205
[Cu] Atualização por classe:170916
[Lr] Data última revisão:
170916
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120126
[St] Status:MEDLINE
[do] DOI:10.1007/s00101-011-1954-4


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[PMID]:22433703
[Ti] Título:[Prevention of respiratory infection in patients following surgical intervention].
[So] Source:Vestn Otorinolaringol;(6):88-90, 2011.
[Is] ISSN:0042-4668
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The objective of the present study was to estimate the efficacy of therapy with hexetedine for the prevention of the respiratory infection in the patients undergoing surgical intervention. The study included 64 patients (28 adults and 36 children) ranging in the age from 3 to 55 years who were examined before and after surgery (radiosurgical tonsillectomy and radiosurgical uvulopalatoplasty). Complete clinical examination was supplemented by a microbiological study of cultivated mucosal swab samples obtained from the pharynx before and after the treatment. 41 patients of the study group received hexetedine (hexoral) for the 4 days preceding the operation and during 3 days of the postoperative period. It was shown that the patients treated with hexetedine both in the pre- and postoperative periods experienced a substantial decrease in microbial infestation of pharyngeal mucosa and accelerated elimination of the inflammatory process. Moreover, the general therapeutic effect on day 5 after surgery was more pronounced in the hexetedine-treated patients compared with controls.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/administração & dosagem
Hexitidina/administração & dosagem
Infecções Respiratórias/prevenção & controle
Tonsilectomia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Pré-Escolar
Seres Humanos
Meia-Idade
Palato Mole/cirurgia
Radiocirurgia
Infecções Respiratórias/diagnóstico
Infecções Respiratórias/cirurgia
Tonsilectomia/efeitos adversos
Resultado do Tratamento
Úvula/cirurgia
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 852A84Y8LS (Hexetidine)
[Em] Mês de entrada:1206
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:120322
[St] Status:MEDLINE


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[PMID]:21356020
[Au] Autor:Afennich F; Slot DE; Hossainian N; Van der Weijden GA
[Ad] Endereço:School of Dental Hygiene, Hogeschool Utrecht, University of Applied Sciences, Utrecht, The Netherlands.
[Ti] Título:The effect of hexetidine mouthwash on the prevention of plaque and gingival inflammation: a systematic review.
[So] Source:Int J Dent Hyg;9(3):182-90, 2011 Aug.
[Is] ISSN:1601-5037
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To review the literature concerning hexetidine-containing mouthwash as a monotherapy or as an adjunct to oral hygiene in the prevention of plaque accumulation and gingival inflammation. MATERIALS AND METHODS: PubMed-MEDLINE and the Cochrane-CENTRAL were searched through January 2010 to identify appropriate studies. The primary outcome measurements were plaque accumulation and gingivitis parameters. RESULTS: Independent screening of titles and abstracts of 168 papers resulted in six publications that met the eligibility criteria. Mean values and standard deviations were obtained by data extraction. Descriptive comparisons are presented for hexetidine mouthwash and control mouthwashes (chlorhexidine and placebo). CONCLUSIONS: Considering the potential benefits in the light of the observed side effects, hexetidine appears to be a poor alternative to chlorhexidine.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/uso terapêutico
Placa Dentária/prevenção & controle
Gengivite/prevenção & controle
Hexitidina/uso terapêutico
Antissépticos Bucais/uso terapêutico
[Mh] Termos MeSH secundário: Clorexidina/uso terapêutico
Hemorragia Gengival/prevenção & controle
Seres Humanos
Higiene Bucal
Ensaios Clínicos Controlados Aleatórios como Assunto
Projetos de Pesquisa
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Infective Agents, Local); 0 (Mouthwashes); 852A84Y8LS (Hexetidine); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1112
[Cu] Atualização por classe:131121
[Lr] Data última revisão:
131121
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:110302
[St] Status:MEDLINE
[do] DOI:10.1111/j.1601-5037.2010.00478.x


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[PMID]:21325838
[Au] Autor:Frey Tirri B
[Ad] Endereço:Women's Hospital, University Hospital Basel, Basel, Switzerland. bfrey@uhbs.ch
[Ti] Título:Antimicrobial topical agents used in the vagina.
[So] Source:Curr Probl Dermatol;40:36-47, 2011.
[Is] ISSN:1662-2944
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Vaginally applied antimicrobial agents are widely used in the vagina in women with lower genital tract infections. An 'antimicrobial' is a general term that refers to a group of drugs that are effective against bacteria, fungi, viruses and protozoa. Topical treatments can be prescribed for a wide variety of vaginal infections. Many bacterial infections, such as bacterial vaginosis, desquamative inflammatory vaginitis or, as some European authors call it, aerobic vaginitis as well as infection with Staphylococcus aureus or group A streptococci, may be treated in this way. Candida vulvovaginitis is a fungal infection that is very amenable to topical treatment. The most common viral infections which can be treated with topical medications are condylomata acuminata and herpes simplex. The most often encountered protozoal vaginitis, which is caused by Trichomonas vaginalis, may be susceptible to topical medications, although this infection is treated systemically. This chapter covers the wide variety of commonly used topical antimicrobial agents for these diseases and focuses on the individual therapeutic agents and their clinical efficacy. In addition, potential difficulties that can occur in practice, as well as the usage of these medications in the special setting of pregnancy, are described in this chapter.
[Mh] Termos MeSH primário: Anti-Infecciosos Locais/administração & dosagem
Vaginite/tratamento farmacológico
[Mh] Termos MeSH secundário: Administração Intravaginal
Aminoquinolinas/administração & dosagem
Anti-Infecciosos Locais/efeitos adversos
Antifúngicos/administração & dosagem
Antivirais/administração & dosagem
Azóis/administração & dosagem
Clindamicina/administração & dosagem
Dequalínio/administração & dosagem
Feminino
Hexitidina/administração & dosagem
Seres Humanos
Metronidazol/administração & dosagem
Nistatina/administração & dosagem
Podofilotoxina/administração & dosagem
Gravidez
Complicações Infecciosas na Gravidez/tratamento farmacológico
Ácido Tricloroacético/administração & dosagem
Vaginite/complicações
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Aminoquinolines); 0 (Anti-Infective Agents, Local); 0 (Antifungal Agents); 0 (Antiviral Agents); 0 (Azoles); 1400-61-9 (Nystatin); 140QMO216E (Metronidazole); 3U02EL437C (Clindamycin); 5V2JDO056X (Trichloroacetic Acid); 852A84Y8LS (Hexetidine); E7QC7V26B8 (Dequalinium); L36H50F353 (Podophyllotoxin); P1QW714R7M (imiquimod)
[Em] Mês de entrada:1106
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:110218
[St] Status:MEDLINE
[do] DOI:10.1159/000321047



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