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  1 / 21 MEDLINE  
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[PMID]:27776226
[Au] Autor:Zeng X; Chen J; Qu R; Pan X; Wang Z
[Ad] Endereço:State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Nanjing University, Nanjing, 210023, China; College of Chemistry and Chemical Engineering, Xinyang Normal University, Henan, Xinyang, 464000, China.
[Ti] Título:The OH-initiated atmospheric chemical reactions of polyfluorinated dibenzofurans and polychlorinated dibenzofurans: A comparative theoretical study.
[So] Source:Chemosphere;168:10-17, 2017 Feb.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The atmospheric chemical reactions of some polyfluorinated dibenzofurans (PFDFs) and polychlorinated dibenzofurans (PCDFs), initiated by OH radical, were investigated by performing theoretical calculations using density functional theory (DFT) and B3LYP/6-311++G(2df,p) method. The obtained results indicate that OH addition reactions of PFDFs and PCDFs occurring at C and C sites are thermodynamic spontaneous changes and the branching ratio of the PF(C)DF-OH adducts is decided primarily by kinetic factor. The OH addition reactions of PFDFs taking place at fluorinated C positions are kinetically comparable with those occurring at nonfluorinated C positions, while OH addition reactions of PCDFs occurring at chlorinated C sites are negligible. The total rate constants of the addition reactions of PFDFs or PCDFs become smaller with consecutive fluorination or chlorination, and substituting at C position has more adverse effects than substitution at other sites. The succedent O addition reactions of PF(C)DF-OH adducts are thermodynamic nonspontaneous processes under the atmospheric conditions, and have high Gibbs free energies of activation (Δ G ). The substituted dibenzofuranols are the primary oxidation products for PCDFs under the atmospheric conditions. However, other oxidative products may also be available for PFDFs besides substituted dibenzofuranols.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/química
Dibenzofuranos/química
Radical Hidroxila/química
[Mh] Termos MeSH secundário: Dibenzofuranos Policlorados/química
Monitoramento Ambiental
Halogenação
Cinética
Modelos Teóricos
Oxirredução
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Dibenzofurans); 0 (Dibenzofurans, Polychlorinated); 3352-57-6 (Hydroxyl Radical)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171212
[Lr] Data última revisão:
171212
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE


  2 / 21 MEDLINE  
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[PMID]:28302335
[Au] Autor:Pan W; Fu J; Zhang A
[Ad] Endereço:State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China.
[Ti] Título:Theoretical study on the formation mechanism of pre-intermediates for PXDD/Fs from 2-Bromophenol and 2-Chlorophenol precursors via radical/molecule reactions.
[So] Source:Environ Pollut;225:439-449, 2017 Jun.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This study investigates reaction pathways for the formation of pre-PXDD/F intermediates via a radical/molecule mechanism. Thermodynamic and kinetic parameters for the combination reactions of 2-bromophenol (2-BP) and 2-chlorophenol (2-CP) precursors with key radical species including the phenoxy radicals, the phenyl radicals and the phenoxyl diradicals were calculated in detail. The couplings of phenoxy radicals with 2-B(C)P tend to produce pre-PXDD intermediates of halogenated o-phenoxyphenol. The combinations of phenyl and phenoxyl diradicals with 2-B(C)P produce two types of structures, i.e., dihydroxybiphenyl and o-phenoxyphenyl, which exclusively act as prestructures of PXDFs. These condensation reactions, especially those involving the phenyl C atom sites in phenyl and phenoxyl diradicals, are proven to be both thermodynamically and kinetically favorable and are nearly comparable with the corresponding steps involved in the radical/radical reactions. Most importantly, reactions of phenyl and phenoxyl diradicals with halogenated phenols solely lead to the formation of PXDFs, which to some extent provides a plausible explanation for the high PXDF-to-PXDD ratios in the real environment. Therefore, our study reveals the pivotal role of the radical/molecule mechanism in homogeneous gas-phase PXDD/F formation, especially in PXDF formation. The present results fill in a knowledge gap that has hitherto existed regarding dioxin formation and improve our understanding of PXDD/F formation characteristics in the environment.
[Mh] Termos MeSH primário: Clorofenóis/química
Dibenzofuranos/química
Dioxinas/química
Modelos Químicos
Fenóis/química
[Mh] Termos MeSH secundário: Benzofuranos/química
Halogenação
Cinética
Modelos Teóricos
Dibenzodioxinas Policloradas
Termodinâmica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Benzofurans); 0 (Chlorophenols); 0 (Dibenzofurans); 0 (Dioxins); 0 (Phenols); 0 (Polychlorinated Dibenzodioxins); 3229-70-7 (phenoxy radical); A0UB206YF0 (2-bromophenol); K9KAV4K6BN (2-chlorophenol)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170318
[St] Status:MEDLINE


  3 / 21 MEDLINE  
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[PMID]:28079378
[Au] Autor:Carpentier C; Queiroz EF; Marcourt L; Wolfender JL; Azelmat J; Grenier D; Boudreau S; Voyer N
[Ti] Título:Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.
[So] Source:J Nat Prod;80(1):210-214, 2017 Jan 27.
[Is] ISSN:1520-6025
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Chemical investigation of the methanol extract of the lichen Stereocaulon paschale collected in Nunavik, Canada, led to the isolation and identification of two new dibenzofurans (1 and 3) and 11 known lichen metabolites. The structures of the new compounds were established by analysis of 1D and 2D NMR spectroscopic and high-resolution mass spectrometric data. Herein, the first isolation of ascomatic acid dibenzofuran derivatives (1-3) from a whole lichen organism is reported. In addition, some of the isolated metabolites showed antibacterial activity against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans.
[Mh] Termos MeSH primário: Antibacterianos/isolamento & purificação
Dibenzofuranos/isolamento & purificação
Dibenzofuranos/farmacologia
Líquens/química
Porphyromonas gingivalis/efeitos dos fármacos
[Mh] Termos MeSH secundário: Antibacterianos/química
Antibacterianos/farmacologia
Canadá
Dibenzofuranos/química
Espectroscopia de Ressonância Magnética
Testes de Sensibilidade Microbiana
Estrutura Molecular
Streptococcus mutans
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 0 (Dibenzofurans)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170808
[Lr] Data última revisão:
170808
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170113
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jnatprod.6b00831


  4 / 21 MEDLINE  
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[PMID]:28069368
[Au] Autor:Champoux L; Rail JF; Lavoie RA
[Ad] Endereço:Wildlife and Landscape Science Directorate, Science and Technology Branch, Environment and Climate Change Canada, Quebec, Quebec, G1J 0C3, Canada. Electronic address: louise.champoux@canada.ca.
[Ti] Título:Polychlorinated dibenzo-p-dioxins, dibenzofurans, and flame retardants in northern gannet (Morus bassanus) eggs from Bonaventure Island, Gulf of St. Lawrence, 1994-2014.
[So] Source:Environ Pollut;222:600-608, 2017 Mar.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Northern gannet (Morus bassanus) eggs from Bonaventure Island, Québec, Canada, were collected to monitor concentrations of contaminants. Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/Fs) and non-ortho polychlorinated biphenyls (PCBs) were measured in eggs from 2004 and 2009, and several brominated and nonbrominated flame retardants (FRs) were measured every 2-5 years in eggs from 1994 to 2014. The sum (Σ) concentrations of PCDDs/Fs were significantly lower in 2009 relative to 2004, but the total toxic equivalent concentrations for PCDDs, PCDFs, and PCBs showed no significant differences (196 ng/kg wet weight (ww) in 2004 and 220 ng/kg ww in 2009). The mean ΣFR concentrations decreased significantly between 1994 and 2014, from 58 ng/g ww to 19 ng/g ww. Hexabromocyclododecane (HBCDD) was the principal nonbrominated FR detected in gannet eggs and ranged from <1.0 ng/g ww to 6.9 ng/g ww. The PCDD/F and nonortho PCB profiles were dominated by 2,3,7,8- tetrachloro-dibenzofuran (2,3,7,8-TCDF; from 26.2 ng/g ww to 34.8 ng/kg ww) and PCB-77 (from 1580 ng/g ww to 2650 ng/kg ww), respectively. Although the values of both ecological tracer stable isotopes of carbon (δ C) and nitrogen (δ N) showed differences among the years, no temporal trends were observed, which indicates relatively stable adults' diet and foraging area over this time period. The trends over time in concentrations of the studied contaminants likely reflect a decrease in environmental contamination. The mean 2012 eggshell thickness was 10% lower than the pre-DDT value and corresponded to a year of poor reproductive success.
[Mh] Termos MeSH primário: Aves
Dibenzofuranos/análise
Poluentes Ambientais/análise
Retardadores de Chama/análise
Óvulo/química
Dibenzodioxinas Policloradas/análise
[Mh] Termos MeSH secundário: Animais
Dibenzofuranos/toxicidade
Casca de Ovo/efeitos dos fármacos
Exposição Ambiental/análise
Poluentes Ambientais/toxicidade
Retardadores de Chama/toxicidade
Ilhas
Óvulo/efeitos dos fármacos
Dibenzodioxinas Policloradas/toxicidade
Quebeque
Reprodução/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Environmental Pollutants); 0 (Flame Retardants); 0 (Polychlorinated Dibenzodioxins)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170111
[St] Status:MEDLINE


  5 / 21 MEDLINE  
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[PMID]:27939438
[Au] Autor:Li J; Lv Z; Du L; Li X; Hu X; Wang C; Niu Z; Zhang Y
[Ad] Endereço:School of Environmental Science and Engineering, Tianjin University, Tianjin 300072, China.
[Ti] Título:Emission characteristic of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) from medical waste incinerators (MWIs) in China in 2016: A comparison between higher emission levels of MWIs and lower emission levels of MWIs.
[So] Source:Environ Pollut;221:437-444, 2017 Feb.
[Is] ISSN:1873-6424
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Emission characteristic of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs) from 12 medical waste incinerators (MWIs) which have a total yearly capacity of 523 440 ton medical waste and accounted for 8.1% of total yearly capacity of 246 MWIs in China were studied. The congeners profile, emissions and toxic equivalent concentrations (TEQ) indicators of PCDD/Fs in stack gas from two groups of MWIs were researched, and the possible formation mechanisms of PCDD/Fs from MWIs were preliminarily discussed. The results of present study were summarized as follows. (1) The total concentrations and TEQ of PCDD/Fs in stack gas from MWIs were 0.516-122.803 ng Nm and 0.031-3.463 ng I-TEQ Nm , respectively. (2) 1,2,3,4,6,7,8-H7CDF, O8CDD, O8CDF and 1,2,3,4,6,7,8-H7CDD were the indicatory PCDD/Fs of MWI source, which could be used to apportion the sources of PCDD/Fs in environmental medium in China. (3) The emission factors of PCDD/Fs from MWIs ranged from 32.7 to 4900.0 ng I-TEQ ton with a mean of 1923.6 ng I-TEQ ton . (4) The gas emissions of PCDD/Fs from researched 12 MWIs and all of MWIs in China in 2016 were 37.742 and 465.951 mg I-TEQ year , respectively. (5) 1,2,3,7,8,9-H6CDF and 1,2,3,4,7,8-H6CDF were effective TEQ indicators for the real-time monitoring of the PCDD/Fs emission. (6) The congeners profile and factor composition of PCDD/Fs in stack gas from two groups of MWIs were researched based on positive matrix factorization (PMF) model, and the possible formation mechanisms of PCDD/Fs from MWIs were preliminarily discussed.
[Mh] Termos MeSH primário: Poluentes Atmosféricos/análise
Poluição do Ar/estatística & dados numéricos
Dibenzofuranos Policlorados/análise
Incineração
Eliminação de Resíduos de Serviços de Saúde
Dibenzodioxinas Policloradas/análise
[Mh] Termos MeSH secundário: Benzofuranos/análise
China
Dibenzofuranos
Monitoramento Ambiental
Resíduos de Serviços de Saúde
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Air Pollutants); 0 (Benzofurans); 0 (Dibenzofurans); 0 (Dibenzofurans, Polychlorinated); 0 (Medical Waste); 0 (Medical Waste Disposal); 0 (Polychlorinated Dibenzodioxins)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE


  6 / 21 MEDLINE  
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[PMID]:27928942
[Au] Autor:Lambiase S; Serpe FP; Cavallo S; Rosato G; Baldi L; Neri B; Esposito M
[Ad] Endereço:a Dipartimento di Chimica , Istituto Zooprofilattico Sperimentale del Mezzogiorno , Portici , Italy.
[Ti] Título:Occurrence of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in eggs from free-range hens in Campania (southern Italy) and risk evaluation.
[So] Source:Food Addit Contam Part A Chem Anal Control Expo Risk Assess;34(1):56-64, 2017 Jan.
[Is] ISSN:1944-0057
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Hens' eggs collected in home-producing farms located in different areas of the Campania region of southern Italy were analysed for six NDL-polychlorobiphenyls (PCB indicators), 17 polychlorodibenzo-p-dioxins (PCDDs) and polychlorodibenzofurans (PCDFs), and 12 congeners of dioxin-like PCBs (DL-PCBs). In the investigated area, waste from civil, industrial and hospital activities was illegally dumped and in many cases burned, so the area is called the 'Land of fire'. This illicit practice has been considered the main source of pollution in this territory and the cause of the persistent organic pollutants' (POPs) contamination in the neighbouring lands intended for agricultural use and livestock. The results, which were obtained from the analysis of 56 samples of eggs, showed levels of contamination by dioxins and PCBs that have often exceeded the action levels set by European Union Recommendation 711/2013 and sometimes even exceeded the maximum levels set by Commission Regulation (EU) 1259/2011. The median PCDD/Fs was 0.41 pg TEQ g fat (range = 0.01-6.18 pg TEQ g fat) and the median concentration of DL-PCBs was 0.70 pg TEQ g fat (range = 0.01-14.60 pg TEQ g fat), whereas NDL-PCBs median was 7.35 ng g fat (range = 0.48-67.55 ng g fat). Nevertheless, the estimated weekly intake (EWI) calculated for consumers of eggs home produced in Campania is lower than the tolerable weekly intake (TWI) established by the European Union Scientific Committee on Food (SCF).
[Mh] Termos MeSH primário: Dibenzofuranos/análise
Ovos/análise
Bifenilos Policlorados/análise
Dibenzodioxinas Policloradas/análise
[Mh] Termos MeSH secundário: Animais
Galinhas
Itália
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Polychlorinated Dibenzodioxins); DFC2HB4I0K (Polychlorinated Biphenyls)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170227
[Lr] Data última revisão:
170227
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161209
[St] Status:MEDLINE
[do] DOI:10.1080/19440049.2016.1260167


  7 / 21 MEDLINE  
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[PMID]:27662860
[Au] Autor:Iyer R; Aggarwal J; Iken B
[Ad] Endereço:Center for Life Sciences Technology, Engineering Technology, University of Houston, 300 Technology Building, Houston, TX, 77204, USA. riyer@uh.edu.
[Ti] Título:A review of the Texas, USA San Jacinto Superfund site and the deposition of polychlorinated dibenzo-p-dioxins and dibenzofurans in the San Jacinto River and Houston Ship Channel.
[So] Source:Environ Sci Pollut Res Int;23(23):23321-23338, 2016 Dec.
[Is] ISSN:1614-7499
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The San Jacinto River (SJR) waste pits that lie just under the 1-10 overpass in eastern Harris County east of Houston, Texas, USA, were created in the 1960s as dumping grounds for paper mill waste. The deposition of this waste led to accumulation of highly toxic polychlorinated dibenzo-p-dioxins and dibenzofurans (PCCDDs/PCDFs) over the course of several decades. After abandonment, the waste material eventually became submerged under the waters of the SJR, resulting in widespread environmental contamination that currently constitutes a significant health concern for eastern Harris County communities. The original waste pits were rediscovered in 2005, and the San Jacinto waste site is now a designated EPA superfund site. The objective of this review then is to discuss the history and current state of containment around the San Jacinto waste pits and analyze spatial and temporal trends in the PCDD/PCDF deposition through the SJR system from the data available. We will discuss the current exposure and health risks represented by the Superfund site and the SJR system itself, as well as the discovery of liver, kidney, brain (glioma), and retinoblastoma cancer clusters in eastern Harris County across multiple census tracts that border the Superfund site. We will also cover the two primary management options, containment versus removal of the waste from the Superfund and provide recommendations for increased monitoring of existing concentrations of polychlorinated waste in the SJR and its nearby associated communities.
[Mh] Termos MeSH primário: Dibenzofuranos/análise
Dibenzodioxinas Policloradas/análise
Poluentes do Solo/análise
Gerenciamento de Resíduos
Poluentes Químicos da Água/análise
[Mh] Termos MeSH secundário: Monitoramento Ambiental
Texas
Instalações de Eliminação de Resíduos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Polychlorinated Dibenzodioxins); 0 (Soil Pollutants); 0 (Water Pollutants, Chemical)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160925
[St] Status:MEDLINE


  8 / 21 MEDLINE  
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[PMID]:27658378
[Au] Autor:Klees M; Bogatzki C; Hiester E
[Ad] Endereço:North-Rhine Westphalian State Agency for Nature, Environment, and Consumer Protection (LANUV NRW), Wallneyer Str. 6, 45133 Essen, Germany. Electronic address: marcel.klees@lanuv.nrw.de.
[Ti] Título:Selective pressurized liquid extraction for the analysis of polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and dibenzofurans in soil.
[So] Source:J Chromatogr A;1468:10-16, 2016 Oct 14.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:During this study a high throughout selective pressurized liquid extraction (SPLE) method was developed and validated for the simultaneous extraction of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/PCDFs) and polychlorinated biphenyls (PCBs) from soil. To that end, extraction rates of PCBs from soil utilizing different extraction solvents and different extraction temperatures were investigated whereas extraction rates were comparable for toluene, n-hexane and dichloromethane (extraction conditions for all utilized solvents: 33mL PLE extraction cell, extraction temperature: 110°C, static extraction time: 5min, flush volume: 60%, purge 90s). Ratios of native PCBs and PCDD/PCDFs congener concentrations after Soxhlet and selective pressurized liquid extraction (SPLE) showed that SPLE is an alternative sample preparation step for the simultaneous determination of PCDD/PCDFs and PCBs in soil. Additional clean-up steps for the separation of PCBs and PCDD/PCDFs utilizing alumina were performed in order to avoid interferences between the component classes.
[Mh] Termos MeSH primário: Dibenzofuranos/análise
Monitoramento Ambiental/métodos
Extração Líquido-Líquido
Bifenilos Policlorados/análise
Dibenzodioxinas Policloradas/análise
Poluentes do Solo/análise
Solo/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Polychlorinated Dibenzodioxins); 0 (Soil); 0 (Soil Pollutants); DFC2HB4I0K (Polychlorinated Biphenyls)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160924
[St] Status:MEDLINE


  9 / 21 MEDLINE  
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[PMID]:27575567
[Au] Autor:Tuomisto J; Airaksinen R; Kiviranta H; Tukiainen E; Pekkanen J; Tuomisto JT
[Ad] Endereço:Department of Health Protection, National Institute for Health and Welfare, Kuopio, FI-70200, Finland. Electronic address: jouko.tuomisto@thl.fi.
[Ti] Título:A pharmacokinetic analysis and dietary information are necessary to confirm or reject the hypothesis on persistent organic pollutants causing type 2 diabetes.
[So] Source:Toxicol Lett;261:41-48, 2016 Nov 02.
[Is] ISSN:1879-3169
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A number of studies have found an association between the concentrations of persistent organic pollutants (POP) and type 2 diabetes. Causality has remained uncertain. This study describes the pharmacokinetic behavior of PCDD/Fs (polychlorinated dibenzo-p-dioxins and dibenzofurans) both in a theoretical model based on elimination rate constants, and in a group of 409 adult surgical patients with known PCDD/F concentrations and dietary information. A model assuming 10% annual decrease in past PCDD/F intake, predicted the measured profile of TEQ (toxic equivalents) in the patient population fairly well. The dominant determinant of PCDD/F level was age, and the level in patients was also associated with consumption of animal source products. Predicted daily intakes correlated with diet, but also with body mass index (BMI), indicating that high BMI was preceded by high consumption of foods containing PCDD/Fs. The results suggest that a third factor, e.g. high intake of animal source foods, could explain both higher levels of POPs in the body and higher incidence of type 2 diabetes, and BMI is not sufficient in describing the confounding caused by diet. Thus, to fully address the causality between POPs and type 2 diabetes, careful studies considering the pharmacokinetics of the studied compounds, and including the analysis of food consumption, are needed.
[Mh] Termos MeSH primário: Diabetes Mellitus Tipo 2/induzido quimicamente
Dibenzofuranos/farmacocinética
Poluentes Ambientais/farmacocinética
Poluentes Ambientais/toxicidade
Contaminação de Alimentos
Dibenzodioxinas Policloradas/toxicidade
[Mh] Termos MeSH secundário: Índice de Massa Corporal
Registros de Dieta
Seres Humanos
Dibenzodioxinas Policloradas/farmacocinética
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Environmental Pollutants); 0 (Polychlorinated Dibenzodioxins)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170207
[Lr] Data última revisão:
170207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160831
[St] Status:MEDLINE


  10 / 21 MEDLINE  
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[PMID]:27570874
[Au] Autor:Dharmarathne NK; Mackie JC; Kennedy EM; Stockenhuber M
[Ad] Endereço:Process Safety and Environmental Protection Group, School of Engineering, The University of Newcastle , Callaghan, NSW 2308, Australia.
[Ti] Título:Gas Phase Thermal Oxidation of Endosulfan and Formation of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans.
[So] Source:Environ Sci Technol;50(18):10106-13, 2016 Sep 20.
[Is] ISSN:1520-5851
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This paper investigates the thermal decomposition of technical endosulfan under oxidative conditions and the subsequent formation of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans (PCDD/F, dioxins), and their precursors. Both quantum chemical calculations and laboratory experiments were employed to investigate the pathways of oxidation of endosulfan. The laboratory scale apparatus used consists of a tubular reactor and product collection system and analysis train. The results report the effect of temperature (523-923 K) and O2 concentration on PCDD/F formation in a N2 bath gas at a residence time of 5 s. The decomposition of endosulfan produces two types of PCDD/F precursors, involving all chlorinated benzenes (CBz) and chlorinated phenols (CPh). Oxidation of endosulfan favors the formation of PCDF over PCDD. Octachlorodibenzofuran is the most abundant homologue group detected in all experiments. The maximum emission factor for PCDD/F was observed at 923 K and O2 content of 6% and corresponds to 64 ng TEQ-WHO2005 per mg of endosulfan and a total dioxin concentration of 1131 ng/mg of endosulfan.
[Mh] Termos MeSH primário: Endossulfano
Dibenzodioxinas Policloradas
[Mh] Termos MeSH secundário: Dibenzofuranos
Dioxinas
Oxirredução
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dibenzofurans); 0 (Dioxins); 0 (Polychlorinated Dibenzodioxins); OKA6A6ZD4K (Endosulfan)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170608
[Lr] Data última revisão:
170608
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160830
[St] Status:MEDLINE
[do] DOI:10.1021/acs.est.6b03280



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