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[PMID]:29311546
[Au] Autor:Yang JE; Park SJ; Kim WJ; Kim HJ; Kim BJ; Lee H; Shin J; Lee SY
[Ad] Endereço:Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering (BK21 Plus Program), Center for Systems and Synthetic Biotechnology, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Repu
[Ti] Título:One-step fermentative production of aromatic polyesters from glucose by metabolically engineered Escherichia coli strains.
[So] Source:Nat Commun;9(1):79, 2018 01 08.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Aromatic polyesters are widely used plastics currently produced from petroleum. Here we engineer Escherichia coli strains for the production of aromatic polyesters from glucose by one-step fermentation. When the Clostridium difficile isocaprenoyl-CoA:2-hydroxyisocaproate CoA-transferase (HadA) and evolved polyhydroxyalkanoate (PHA) synthase genes are overexpressed in a D-phenyllactate-producing strain, poly(52.3 mol% 3-hydroxybutyrate (3HB)-co-47.7 mol% D-phenyllactate) can be produced from glucose and sodium 3HB. Also, various poly(3HB-co-D-phenyllactate) polymers having 11.0, 15.8, 20.0, 70.8, and 84.5 mol% of D-phenyllactate are produced from glucose as a sole carbon source by additional expression of Ralstonia eutropha ß-ketothiolase (phaA) and reductase (phaB) genes. Fed-batch culture of this engineered strain produces 13.9 g l of poly(61.9 mol% 3HB-co-38.1 mol% D-phenyllactate). Furthermore, different aromatic polyesters containing D-mandelate and D-3-hydroxy-3-phenylpropionate are produced from glucose when feeding the corresponding monomers. The engineered bacterial system will be useful for one-step fermentative production of aromatic polyesters from renewable resources.
[Mh] Termos MeSH primário: Escherichia coli/metabolismo
Fermentação
Glucose/metabolismo
Engenharia Metabólica/métodos
Poliésteres/metabolismo
[Mh] Termos MeSH secundário: Ácido 3-Hidroxibutírico/metabolismo
Acetil-CoA C-Aciltransferase/genética
Acetil-CoA C-Aciltransferase/metabolismo
Aciltransferases/genética
Aciltransferases/metabolismo
Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Clostridium difficile/enzimologia
Clostridium difficile/genética
Coenzima A-Transferases/genética
Coenzima A-Transferases/metabolismo
Cupriavidus necator/enzimologia
Cupriavidus necator/genética
Escherichia coli/genética
Lactatos/metabolismo
Oxirredutases/genética
Oxirredutases/metabolismo
Polietilenotereftalatos/metabolismo
Polímeros/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Lactates); 0 (Polyesters); 0 (Polyethylene Terephthalates); 0 (Polymers); 156-05-8 (3-phenyllactic acid); EC 1.- (Oxidoreductases); EC 2.3.- (Acyltransferases); EC 2.3.1.- (poly(3-hydroxyalkanoic acid) synthase); EC 2.3.1.16 (Acetyl-CoA C-Acyltransferase); EC 2.8.3.- (Coenzyme A-Transferases); IY9XDZ35W2 (Glucose); TZP1275679 (3-Hydroxybutyric Acid)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180305
[Lr] Data última revisão:
180305
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-017-02498-w


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[PMID]:29374183
[Au] Autor:Joo S; Cho IJ; Seo H; Son HF; Sagong HY; Shin TJ; Choi SY; Lee SY; Kim KJ
[Ad] Endereço:School of Life Sciences (KNU Creative BioResearch Group), KNU Institute for Microorganisms, Kyungpook National University, Daehak-ro 80, Buk-gu, Daegu, 41566, Republic of Korea.
[Ti] Título:Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation.
[So] Source:Nat Commun;9(1):382, 2018 01 26.
[Is] ISSN:2041-1723
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Plastics, including poly(ethylene terephthalate) (PET), possess many desirable characteristics and thus are widely used in daily life. However, non-biodegradability, once thought to be an advantage offered by plastics, is causing major environmental problem. Recently, a PET-degrading bacterium, Ideonella sakaiensis, was identified and suggested for possible use in degradation and/or recycling of PET. However, the molecular mechanism of PET degradation is not known. Here we report the crystal structure of I. sakaiensis PETase (IsPETase) at 1.5 Å resolution. IsPETase has a Ser-His-Asp catalytic triad at its active site and contains an optimal substrate binding site to accommodate four monohydroxyethyl terephthalate (MHET) moieties of PET. Based on structural and site-directed mutagenesis experiments, the detailed process of PET degradation into MHET, terephthalic acid, and ethylene glycol is suggested. Moreover, other PETase candidates potentially having high PET-degrading activities are suggested based on phylogenetic tree analysis of 69 PETase-like proteins.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Burkholderiales/enzimologia
Poluentes Ambientais/química
Hidrolases/química
Polietilenotereftalatos/química
[Mh] Termos MeSH secundário: Sequência de Aminoácidos
Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Biodegradação Ambiental
Burkholderiales/química
Domínio Catalítico
Clonagem Molecular
Cristalografia por Raios X
Poluentes Ambientais/metabolismo
Escherichia coli/genética
Escherichia coli/metabolismo
Etilenoglicol/química
Etilenoglicol/metabolismo
Expressão Gênica
Hidrolases/genética
Hidrolases/metabolismo
Cinética
Simulação de Acoplamento Molecular
Ácidos Ftálicos/química
Ácidos Ftálicos/metabolismo
Polietilenotereftalatos/metabolismo
Ligação Proteica
Domínios e Motivos de Interação entre Proteínas
Estrutura Secundária de Proteína
Proteínas Recombinantes/química
Proteínas Recombinantes/genética
Proteínas Recombinantes/metabolismo
Alinhamento de Sequência
Homologia de Sequência de Aminoácidos
Especificidade por Substrato
Termodinâmica
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Environmental Pollutants); 0 (Phthalic Acids); 0 (Polyethylene Terephthalates); 0 (Recombinant Proteins); 6S7NKZ40BQ (terephthalic acid); EC 3.- (Hydrolases); FC72KVT52F (Ethylene Glycol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180128
[St] Status:MEDLINE
[do] DOI:10.1038/s41467-018-02881-1


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[PMID]:29350897
[Au] Autor:Tomic A; Milovic N; Marjanovic I; Lekovic; Bjelanovic Z; Sarac M; Vavic N; Ignjatovic L; Stamenkovic D; Mickovic S
[Ti] Título:Aortobifemoral reconstruction and renal transplantation in a patient with abdominal aortic aneurysm and occlusion of iliac arteries: A case report.
[So] Source:Vojnosanit Pregl;74(1):81-4, 2017 Jan.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Ab] Resumo:Introduction: Aortoiliac occlusive disease and abdominal aortic aneurysm in patients with renal insufficiency on hemodialysis can significantly influence the success of renal transplantation. In the recent past, advanced atherosclerosis was considered as contraindication for renal transplantation. Complicated creation of vascular anastomoses and progression of occlusive or aneurysmal disease were the main reasons. Case report: We presented a 52-year-old man with a 5-year history of end-stage renal disease on haemodialysis. The patient was previously excluded from renal transplantation program because of severe aortoiliac atherosclerosis and abdominal aortic aneurysm. Resection of abdominal aortic aneurysm with occlusion of the iliac arteries and reconstruction with aortobifemoral synthetic grafts was performed and followed by cadaveric renal transplantation. Conclusion: Advanced atherosclerotic disease in aortoiliac segment requires elective vascular surgical reconstruction, as part of preparation for renal transplantation in patients with end-stage renal disease.
[Mh] Termos MeSH primário: Aneurisma da Aorta Abdominal/cirurgia
Arteriopatias Oclusivas/cirurgia
Implante de Prótese Vascular/métodos
Artéria Femoral/cirurgia
Artéria Ilíaca/cirurgia
Falência Renal Crônica/cirurgia
Transplante de Rim
[Mh] Termos MeSH secundário: Aneurisma da Aorta Abdominal/complicações
Aneurisma da Aorta Abdominal/diagnóstico por imagem
Aortografia/métodos
Arteriopatias Oclusivas/complicações
Arteriopatias Oclusivas/diagnóstico por imagem
Prótese Vascular
Implante de Prótese Vascular/instrumentação
Angiografia por Tomografia Computadorizada
Artéria Femoral/diagnóstico por imagem
Seres Humanos
Artéria Ilíaca/diagnóstico por imagem
Falência Renal Crônica/complicações
Falência Renal Crônica/diagnóstico
Masculino
Meia-Idade
Polietilenotereftalatos
Desenho de Prótese
Resultado do Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180120
[St] Status:MEDLINE
[do] DOI:10.2298/VSP140609139T


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[PMID]:28740857
[Au] Autor:Eusebio L; Capelli L; Sironi S
[Ad] Endereço:Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milano, Italy.
[Ti] Título:H S Loss through Nalophan™ Bags: Contributions of Adsorption and Diffusion.
[So] Source:ScientificWorldJournal;2017:9690704, 2017.
[Is] ISSN:1537-744X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hydrogen-sulfide (H S) is a molecule of small dimensions typically present in the odor emissions from different plants. The European Standard EN 13725:2003 set a maximum storage time allowed of 30 hours, during which the sampling bag has to maintain the mixture of odorants with minimal changes. This study investigates the H S losses through Nalophan bags and it shows that nonnegligible losses of H S can be observed. The percent H S loss after 30 hrs with respect to the initial concentration is equal to 33% ± 3% at a relative humidity of 20% and equal to 22% ± 1% at a relative humidity of 60%. The average quantity of adsorbed H S at 30 h is equal to 2.17 10 g /g at a storage humidity of 20% and equal to 1.79 10 g /g at a storage humidity of 60%. The diffusion coefficients of H S through Nalophan, for these two humidity conditions tested, are comparable (i.e., 7.5 10 m /sec at 20% humidity and 6.6 10 m /sec at 60% humidity).
[Mh] Termos MeSH primário: Umidade
Sulfeto de Hidrogênio/análise
Polietilenotereftalatos
[Mh] Termos MeSH secundário: Adsorção
Difusão
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates); YY9FVM7NSN (Hydrogen Sulfide)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180102
[Lr] Data última revisão:
180102
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170726
[St] Status:MEDLINE
[do] DOI:10.1155/2017/9690704


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[PMID]:28470326
[Au] Autor:Puslecki M; Perek B; Stefaniak S; Siniawski A; Oszkinis G; Jemielity M
[Ad] Endereço:Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, Poznan, Poland.
[Ti] Título:Successful surgical treatment of a subtotal descending aortic occlusion.
[So] Source:Cardiovasc J Afr;28(2):e1-e3, 2017 Apr 23.
[Is] ISSN:1680-0745
[Cp] País de publicação:South Africa
[La] Idioma:eng
[Ab] Resumo:We present the case of a 33-year-old man with middle aortic syndrome. The final diagnosis was established with magnetic resonance imaging. He underwent a successful aorto-aortic bypass. Two-year follow-up imaging showed the new graft was patent, with no abnormalities at the anastomosis sites. At the last follow-up examination he was asymptomatic with no neurological dysfunction.
[Mh] Termos MeSH primário: Aorta Torácica/cirurgia
Doenças da Aorta/cirurgia
Arteriopatias Oclusivas/cirurgia
Implante de Prótese Vascular
[Mh] Termos MeSH secundário: Adulto
Aorta Torácica/diagnóstico por imagem
Aorta Torácica/fisiopatologia
Doenças da Aorta/diagnóstico por imagem
Doenças da Aorta/fisiopatologia
Arteriopatias Oclusivas/diagnóstico por imagem
Arteriopatias Oclusivas/fisiopatologia
Prótese Vascular
Implante de Prótese Vascular/instrumentação
Seres Humanos
Angiografia por Ressonância Magnética
Masculino
Polietilenotereftalatos
Desenho de Prótese
Fatores de Tempo
Resultado do Tratamento
Grau de Desobstrução Vascular
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171218
[Lr] Data última revisão:
171218
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.5830/CVJA-2016-012


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[PMID]:28763573
[Au] Autor:Holden MT; Carter MCD; Ting SK; Lynn DM; Smith LM
[Ad] Endereço:Department of Chemistry, University of Wisconsin at Madison, 1101 University Avenue, Madison, WI, 53706, USA.
[Ti] Título:Parallel DNA Synthesis on Poly(ethylene terephthalate).
[So] Source:Chembiochem;18(19):1914-1916, 2017 Oct 05.
[Is] ISSN:1439-7633
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:The fabrication of DNA arrays directly on aminolyzed sheets of poly(ethylene terephthalate) (PET) is described. Array surfaces typically employ bifunctional linkers or layers of covalently attached polymers to provide substrate hydroxy groups as synthesis attachment points. An amine treatment is used here to expose hydroxy groups on films of PET. These hydroxy groups can then be used to couple phosphoramidites and initiate the array synthesis without further functionalization steps. Arrays fabricated on these substrates with a maskless array synthesizer are tolerant of the high number of chemical exposure steps required to synthesize relatively long oligonucleotides. The results might be of the greatest use to the synthetic biology community, for whom a flexible and robust substrate could enable new strategies to enhance the throughput of oligonucleotide synthesis.
[Mh] Termos MeSH primário: DNA/síntese química
Polietilenotereftalatos/química
[Mh] Termos MeSH secundário: DNA/química
Estrutura Molecular
Análise de Sequência com Séries de Oligonucleotídeos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates); 9007-49-2 (DNA)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170802
[St] Status:MEDLINE
[do] DOI:10.1002/cbic.201700321


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[PMID]:28683998
[Au] Autor:Kitahara M; Miyagawa S; Fukushima S; Saito A; Shintani A; Akita T; Sawa Y
[Ad] Endereço:Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
[Ti] Título:Biodegradable vs Nonbiodegradable Cardiac Support Device for Treating Ischemic Cardiomyopathy in a Canine Heart.
[So] Source:Semin Thorac Cardiovasc Surg;29(1):51-61, 2017 Spring.
[Is] ISSN:1532-9488
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Clinical studies of the efficacy of the nonbiodegradable CorCap device have shown inconsistent findings, at least in part, because of device-related impairment of diastolic cardiac function. We hypothesized that use of biodegradable material for the cardiac support device could contribute to an improvement in the diastolic function of the failing heart. Polyglycolic acid and polyethylene terephthalate were used to prepare biodegradable and nonbiodegradable cardiac support devices, respectively. Twelve-month-old beagles underwent anterior coronary artery ligation. One week after, the beagles were randomly assigned for implantation of a biodegradable cardiac support device (n = 7), nonbiodegradable cardiac support device (n = 8), or sham operation (n = 8). Twelve weeks after coronary artery ligation, the biodegradable group showed a significantly greater recovery of echocardiographical ejection fraction than the nonbiodegradable and the sham groups (40% ± 3.3%, 32% ± 2.5%, and 29 ± 2.6%, respectively). Of note, diastolic function, as assessed by Tau, -dp/dt min, and end-diastolic pressure-volume relationship in the cardiac catheter, was significantly better in both left and right ventricles in the biodegradable group than in the nonbiodegradable group. Moreover, global end-systolic wall stress was significantly lower in the 2 device groups than in the sham group (P < 0.03). Furthermore, global end-diastolic wall stress was significantly less in the biodegradable device group than in the nonbiodegradable group (P < 0.02). The cardiac support devices made of biodegradable material were more effective in improving systolic function, with preservation of diastolic function in the canine infarct heart, than devices made of nonbiodegradable material.
[Mh] Termos MeSH primário: Implantes Absorvíveis
Procedimentos Cirúrgicos Cardíacos/instrumentação
Cardiomiopatias/cirurgia
Isquemia Miocárdica/complicações
Implante de Prótese/instrumentação
[Mh] Termos MeSH secundário: Animais
Fenômenos Biomecânicos
Procedimentos Cirúrgicos Cardíacos/efeitos adversos
Cardiomiopatias/etiologia
Cardiomiopatias/patologia
Cardiomiopatias/fisiopatologia
Modelos Animais de Doenças
Cães
Contração Miocárdica
Isquemia Miocárdica/fisiopatologia
Miocárdio/patologia
Polietilenotereftalatos/química
Ácido Poliglicólico/química
Desenho de Prótese
Implante de Prótese/efeitos adversos
Recuperação de Função Fisiológica
Estresse Mecânico
Volume Sistólico
Fatores de Tempo
Função Ventricular Esquerda
Função Ventricular Direita
Pressão Ventricular
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates); 26009-03-0 (Polyglycolic Acid)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170708
[St] Status:MEDLINE


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[PMID]:28647251
[Au] Autor:do Prado NT; Heitmann AP; Mansur HS; Mansur AA; Oliveira LCA; de Castro CS
[Ad] Endereço:Department of Chemistry, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Campus Pampulha, 31270-901, BH-MG, Brazil.
[Ti] Título:PET-modified red mud as catalysts for oxidative desulfurization reactions.
[So] Source:J Environ Sci (China);57:312-320, 2017 Jul.
[Is] ISSN:1001-0742
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This work describes the synthesis of catalysts based on red mud/polyethylene terephthalate (PET) composites and their subsequent heat treatment under N atmosphere. The materials were characterized by scanning electron microscopy (SEM), temperature programmed reduction (TPR), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric (TG) analysis and N adsorption/desorption. The catalysts were evaluated in the oxidative desulfurization reaction of dibenzothiophene (DBT) in a biphasic system. The results indicated that the PET impregnation on red mud increased the affinity of the catalyst with the nonpolar phase (fuel), in which the contaminant was dissolved, allowing a higher conversion (up to 80%) and selectivity to the corresponding dibenzothiophene sulfone. The sulfone compound is more polar than DBT and diffused into the polar solvent as indicated by the data obtained via gas chromatography-mass spectrometry (GC-MS).
[Mh] Termos MeSH primário: Modelos Químicos
Polietilenotereftalatos/química
[Mh] Termos MeSH secundário: Adsorção
Catálise
Oxirredução
Espectroscopia de Infravermelho com Transformada de Fourier
Tiofenos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polyethylene Terephthalates); 0 (Thiophenes); 1013-23-6 (dibenzothiophene 5-oxide); Z3D4AJ1R48 (dibenzothiophene)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170626
[St] Status:MEDLINE


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[PMID]:28557788
[Au] Autor:McHenry AR; Wempe MF; Rice PJ
[Ad] Endereço:University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, Colorado.
[Ti] Título:Stability of Extemporaneously Prepared Hydroxychloroquine Sulfate 25-mg/mL Suspensions in Plastic Bottles and Syringes.
[So] Source:Int J Pharm Compd;21(3):251-254, 2017 May-Jun.
[Is] ISSN:1092-4221
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study evaluated the stability of the antimalarial and anti-rheumatic drug hydroxychloroquine sulfate in two commercially available suspension vehicles, Oral Mix and Oral Mix SF (Medisca Pharmaceutique Inc.). Hydroxychloroquine sulfate (25 mg/mL) suspension was prepared, packaged in amber 50-mL polyethylene terephthalate bottles and amber 3-mL syringes, and stored at room temperature or at 4°C. Samples were collected and analyzed over a 16-week period by high-performance liquid chromatography with ultraviolet detection at 340 nm. Approximately 99.8% of the hydroxychloroquine remained at the conclusion of the study, with no observable difference between room temperature and refrigerated storage. Hydroxychloroquine sulfate is stable for at least 90 days in Medisca Oral Mix or Oral Mix SF suspension media at 25°C and 4°C.
[Mh] Termos MeSH primário: Hidroxicloroquina/química
Suspensões/química
[Mh] Termos MeSH secundário: Química Farmacêutica/métodos
Composição de Medicamentos/métodos
Estabilidade de Medicamentos
Armazenamento de Medicamentos/métodos
Plásticos/química
Polietilenotereftalatos/química
Seringas
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plastics); 0 (Polyethylene Terephthalates); 0 (Suspensions); 4QWG6N8QKH (Hydroxychloroquine)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE


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[PMID]:28498875
[Au] Autor:Gok A; Ngendahimana DK; Fagerholm CL; French RH; Sun J; Bruckman LS
[Ad] Endereço:Department of Materials Science and Engineering, Gebze Technical University, Gebze, Kocaeli, Turkey.
[Ti] Título:Predictive models of poly(ethylene-terephthalate) film degradation under multi-factor accelerated weathering exposures.
[So] Source:PLoS One;12(5):e0177614, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Accelerated weathering exposures were performed on poly(ethylene-terephthalate) (PET) films. Longitudinal multi-level predictive models as a function of PET grades and exposure types were developed for the change in yellowness index (YI) and haze (%). Exposures with similar change in YI were modeled using a linear fixed-effects modeling approach. Due to the complex nature of haze formation, measurement uncertainty, and the differences in the samples' responses, the change in haze (%) depended on individual samples' responses and a linear mixed-effects modeling approach was used. When compared to fixed-effects models, the addition of random effects in the haze formation models significantly increased the variance explained. For both modeling approaches, diagnostic plots confirmed independence and homogeneity with normally distributed residual errors. Predictive R2 values for true prediction error and predictive power of the models demonstrated that the models were not subject to over-fitting. These models enable prediction under pre-defined exposure conditions for a given exposure time (or photo-dosage in case of UV light exposure). PET degradation under cyclic exposures combining UV light and condensing humidity is caused by photolytic and hydrolytic mechanisms causing yellowing and haze formation. Quantitative knowledge of these degradation pathways enable cross-correlation of these lab-based exposures with real-world conditions for service life prediction.
[Mh] Termos MeSH primário: Membranas Artificiais
Polietilenotereftalatos/química
[Mh] Termos MeSH secundário: Luz
Modelos Teóricos
Raios Ultravioleta
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Membranes, Artificial); 0 (Polyethylene Terephthalates)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170513
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0177614



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