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[PMID]: | 29237526 |
[Au] Autor: | Sun LF; Li YY; Huang BX; Fu XY; Yang FH; Ma DL; Zhang Q |
[Ad] Endereço: | Department of Clinical Laboratory, Children's Hospital of Shenzhen, Shenzhen, Guangdong 518038, China. 771369652@qq.com. |
[Ti] Título: | [Establishment of reference ranges of sex hormones for healthy children in Shenzhen, China based on chemiluminescence]. |
[So] Source: | Zhongguo Dang Dai Er Ke Za Zhi;19(12):1257-1262, 2017 Dec. | [Is] ISSN: | 1008-8830 |
[Cp] País de publicação: | China |
[La] Idioma: | chi |
[Ab] Resumo: | OBJECTIVE: To study the reference ranges of six sex hormones, i.e., luteinizing hormone, follicle-stimulating hormone, progesterone, prolactin, estradiol, and testosterone, for healthy children aged 0-18 years in Shenzhen, China. METHODS: Stratified cluster sampling was performed to select 2 178 healthy children aged 0-18 years in the districts of Futian, Luohu, Nanshan, Bao'an, and Longgang in Shenzhen between September 2015 and September 2016. There were 1 219 boys and 959 girls, including 81 neonates, 335 infants, 346 young children, 469 preschool children, 419 school-aged children, and 528 adolescents. The American Beckman DXI800 chemiluminescence meter was used to measure the levels of luteinizing hormone, follicle-stimulating hormone, progesterone, prolactin, estradiol, and testosterone. RESULTS: There were significant differences in the levels of luteinizing hormone, follicle-stimulating hormone, progesterone, prolactin, estradiol, and testosterone between different age groups (P<0.05). There were also significant differences in the levels of these sex hormones between boys and girls in the same age group (P<0.05). The reference ranges of six sex hormones were established for healthy children aged 0-18 years in Shenzhen based on the levels of these hormones in different age groups. CONCLUSIONS: There are significant differences in sex hormones between different age groups or sex groups. The reference ranges of six sex hormones established for different sexes or ages have great significance in the diagnosis and treatment of endocrine diseases in children. |
[Mh] Termos MeSH primário: |
Hormônios Esteroides Gonadais/sangue
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[Mh] Termos MeSH secundário: |
Adolescente Fatores Etários Criança Pré-Escolar Estradiol/sangue Feminino Hormônio Foliculoestimulante/sangue Seres Humanos Lactente Recém-Nascido Medições Luminescentes Hormônio Luteinizante/sangue Masculino Progesterona/sangue Valores de Referência Testosterona/sangue
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[Pt] Tipo de publicação: | JOURNAL ARTICLE |
[Nm] Nome de substância:
| 0 (Gonadal Steroid Hormones); 3XMK78S47O (Testosterone); 4G7DS2Q64Y (Progesterone); 4TI98Z838E (Estradiol); 9002-67-9 (Luteinizing Hormone); 9002-68-0 (Follicle Stimulating Hormone) |
[Em] Mês de entrada: | 1803 |
[Cu] Atualização por classe: | 180306 |
[Lr] Data última revisão:
| 180306 |
[Sb] Subgrupo de revista: | IM |
[Da] Data de entrada para processamento: | 171215 |
[St] Status: | MEDLINE |
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