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Pesquisa : D08.811.682.690.416.583 [Categoria DeCS]
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  1 / 134 MEDLINE  
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[PMID]:29236385
[Au] Autor:Babenko LM; Shcherbatiuk MM; Skaterna TD; Kosakivska IV
[Ti] Título:Lipoxygenases and their metabolites in formation of plant stress tolerance.
[So] Source:Ukr Biochem J;89(1):5-21, 2017 Jan-Feb.
[Is] ISSN:2409-4943
[Cp] País de publicação:Ukraine
[La] Idioma:eng
[Ab] Resumo:The review focuses on the analysis of new information concerning molecular enzymology of lipoxygenases ­ proteins involved in lipid peroxidation and found in animals and plants. Modern concept of structural features, catalytic characteristics and functions of lipoxygenase family enzymes as well as products of their catalytic activity in plants have been discussed and summarized. Issues of enzyme localization in plant cells and tissues, evolution and distribution of lipoxygenases, involvement in production of signaling substances involved in formation of adaptation response to abiotic and biotic stress factors and in regulation of lipoxygenase signal system activity are highlighted. Participants of the elements signaling of LOX-pathway reception and transduction into genome are considered. Special attention is given to jasmonates, metabolites of the allene oxide synthase branch of the lipoxygenase cascade, because these metabolites have high biological activity, are ubiquitously present in all plant organisms, and are involved in regulation of vitally important processes. Data concerning lipoxygenase phylogeny, possible occurrence of a common predecessor for modern isoforms of the enzyme in pro- and eukaryote have been examined. Some results of our studies that open up possibilities of using the lipoxygenase catalytic activity characteristics as biological markers in plant stress tolerance researches are given.
[Mh] Termos MeSH primário: Adaptação Fisiológica/genética
Regulação da Expressão Gênica de Plantas
Genoma de Planta
Lipoxigenases/genética
Proteínas de Plantas/genética
Plantas/genética
[Mh] Termos MeSH secundário: Evolução Biológica
Ciclopentanos/metabolismo
Oxirredutases Intramoleculares/genética
Oxirredutases Intramoleculares/metabolismo
Lipoxigenases/metabolismo
Redes e Vias Metabólicas/genética
Oxilipinas/metabolismo
Filogenia
Proteínas de Plantas/metabolismo
Plantas/classificação
Plantas/enzimologia
Transdução de Sinais
Estresse Fisiológico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Cyclopentanes); 0 (Oxylipins); 0 (Plant Proteins); 6RI5N05OWW (jasmonic acid); EC 1.13.11.- (Lipoxygenases); EC 5.3.- (Intramolecular Oxidoreductases); EC 5.3.99.6 (hydroperoxide isomerase)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180116
[Lr] Data última revisão:
180116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171214
[St] Status:MEDLINE
[do] DOI:10.15407/ubj89.01.005


  2 / 134 MEDLINE  
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[PMID]:28726099
[Au] Autor:Krutetskaya ZI; Melnitskaya AV; Antonov VG; Nozdrachev AD
[Ad] Endereço:St. Petersburg State University, St. Petersburg, 199034, Russia. z.krutetskaya@spbu.ru.
[Ti] Título:Lipoxygenases modulate the effect of glutoxim on Na transport in the frog skin epithelium.
[So] Source:Dokl Biochem Biophys;474(1):193-195, 2017 May.
[Is] ISSN:1608-3091
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:Using voltage-clamp technique, the involvement of lipoxygenases in the effect of immunomodulatory drug glutoxim on Na transport in frog skin was investigated. It was shown for the first time that preincubation of the skin with lipoxygenase inhibitors caffeic acid, baicalein, and nordihydroguaiaretic acid significantly decreases the stimulatory effect of glutoxim on Na transport. The data suggest the involvement of lipoxygenase oxidation pathway of arachidonic acid metabolism in the glutoxim effect on Na transport in frog skin epithelium.
[Mh] Termos MeSH primário: Lipoxigenases/metabolismo
Oligopeptídeos/farmacologia
Pele/efeitos dos fármacos
Pele/metabolismo
Sódio/metabolismo
[Mh] Termos MeSH secundário: Animais
Anuros
Transporte Biológico/efeitos dos fármacos
Epitélio/efeitos dos fármacos
Epitélio/metabolismo
Cinética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Oligopeptides); 0 (glutoxim); 9NEZ333N27 (Sodium); EC 1.13.11.- (Lipoxygenases)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170721
[St] Status:MEDLINE
[do] DOI:10.1134/S1607672917030073


  3 / 134 MEDLINE  
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[PMID]:28515072
[Au] Autor:Gong Y; Fu Z; Liegl R; Chen J; Hellström A; Smith LE
[Ad] Endereço:Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA; and.
[Ti] Título:ω-3 and ω-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases.
[So] Source:Am J Clin Nutr;106(1):16-26, 2017 Jul.
[Is] ISSN:1938-3207
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Neovascular eye diseases, including retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration, threaten the visual health of children and adults. Current treatment options, including anti-vascular endothelial growth factor therapy and laser retinal photocoagulation, have limitations and are associated with adverse effects; therefore, the identification of additional therapies is highly desirable. Both clinical and experimental studies show that dietary ω-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFAs) reduce retinal and choroidal angiogenesis. The ω-3 LC-PUFA metabolites from 2 groups of enzymes, cyclooxygenases and lipoxygenases, inhibit [and the ω-6 (n-6) LC-PUFA metabolites promote] inflammation and angiogenesis. However, both of the ω-3 and the ω-6 lipid products of cytochrome P450 oxidase 2C promote neovascularization in both the retina and choroid, which suggests that inhibition of this pathway might be beneficial. This review summarizes our current understanding of the roles of ω-3 and ω-6 LC-PUFAs and their enzymatic metabolites in neovascular eye diseases.
[Mh] Termos MeSH primário: Retinopatia Diabética/metabolismo
Ácidos Graxos Ômega-3/metabolismo
Ácidos Graxos Ômega-6/metabolismo
Degeneração Macular/metabolismo
Retina/metabolismo
Neovascularização Retiniana/metabolismo
Retinopatia da Prematuridade/metabolismo
[Mh] Termos MeSH secundário: Sistema Enzimático do Citocromo P-450/metabolismo
Retinopatia Diabética/tratamento farmacológico
Ácidos Graxos Ômega-3/uso terapêutico
Ácidos Graxos Ômega-6/uso terapêutico
Seres Humanos
Lipoxigenases/metabolismo
Degeneração Macular/tratamento farmacológico
Prostaglandina-Endoperóxido Sintases/metabolismo
Retina/patologia
Doenças Retinianas/tratamento farmacológico
Doenças Retinianas/metabolismo
Neovascularização Retiniana/tratamento farmacológico
Retinopatia da Prematuridade/tratamento farmacológico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Fatty Acids, Omega-3); 0 (Fatty Acids, Omega-6); 0 (cytochrome P-450 CYP2C subfamily); 9035-51-2 (Cytochrome P-450 Enzyme System); EC 1.13.11.- (Lipoxygenases); EC 1.14.99.1 (Prostaglandin-Endoperoxide Synthases)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170804
[Lr] Data última revisão:
170804
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170519
[St] Status:MEDLINE
[do] DOI:10.3945/ajcn.117.153825


  4 / 134 MEDLINE  
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[PMID]:28189640
[Au] Autor:Xie Q; Xie J; Tian T; Ma Q; Zhang Q; Zhu B; Cai X
[Ad] Endereço:State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, PR China.
[Ti] Título:Hypoxia triggers angiogenesis by increasing expression of LOX genes in 3-D culture of ASCs and ECs.
[So] Source:Exp Cell Res;352(1):157-163, 2017 Mar 01.
[Is] ISSN:1090-2422
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: This study aimed to investigate the expression changes of LOX (lysyl oxidase) family genes, VEGFA, and VEGFB under hypoxic conditions in a co-culture system of ASCs (adipose-derived stromal cells) and ECs (endothelial cells). MATERIALS AND METHODS: ASCs and ECs were co-cultured under hypoxic and normal oxygen conditions in a 1:1 ratio, and the formation of vessel-like was detected at 7 days. The transwell co-culture system was used and cell lysates were collected at 7 days after co-culture in hypoxic and normal oxygen condition. Semi-quantitative PCR was performed to quantify the mRNA expression of VEGFA, VEGFB, and the LOX genes (LOX, LOXL-1, LOXL-2, LOXL-3, and LOXL-4). Expression changes were determined by densitomery. RESULTS: Enhanced angiogenesis was detected in the co-culture of ASCs and ECs under hypoxic conditions. Among the genes screened, VEGFA, VEGFB, LOXL-1, and LOXL-3 in ECs, both mono-cultured and co-cultured, were significantly enhanced after culturing under hypoxic conditions. In ASCs, VEGFB, LOXL-1, and LOXL-3 were upregulated. CONCLUSIONS: Contact co-culture between ASCs and ECs promotes angiogenesis under hypoxia. LOXL-1 and LOXL-3 expressions were increased in both ASCs and ECs and might play important roles in the enhanced angiogenesis promoted by hypoxia.
[Mh] Termos MeSH primário: Tecido Adiposo/metabolismo
Endotélio Vascular/metabolismo
Hipóxia
Lipoxigenases/genética
Neovascularização Fisiológica/fisiologia
Células Estromais/metabolismo
[Mh] Termos MeSH secundário: Tecido Adiposo/citologia
Técnicas de Cultura de Células
Células Cultivadas
Técnicas de Cocultura
Endotélio Vascular/citologia
Imunofluorescência
Seres Humanos
Lipoxigenases/metabolismo
RNA Mensageiro/genética
Reação em Cadeia da Polimerase em Tempo Real
Reação em Cadeia da Polimerase Via Transcriptase Reversa
Células Estromais/citologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (RNA, Messenger); EC 1.13.11.- (Lipoxygenases)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170530
[Lr] Data última revisão:
170530
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170213
[St] Status:MEDLINE


  5 / 134 MEDLINE  
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[PMID]:28049535
[Au] Autor:Alam F; Saqib QN; Ashraf M
[Ad] Endereço:Department of Pharmacy, COMSATS Institute of Information Technology, 22060, Abbottabad, Pakistan. alamfiaz@ciit.net.pk.
[Ti] Título:Gaultheria trichophylla (Royle): a source of minerals and biologically active molecules, its antioxidant and anti-lipoxygenase activities.
[So] Source:BMC Complement Altern Med;17(1):3, 2017 Jan 03.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Gaultheria trichophylla (Royle) is used as food and for treating many ailments in folk medicine especially against inflammation. The purpose of this in vitro study was to evaluate the ability of extracts of G. trichophylla as anti-oxidant and anti-inflammatory agent and for its mineral contents. METHODS: Powdered plant material (100 g) was extracted with 100 ml each of methanol, chloroform, and n-hexane using soxhlet extractor. Antioxidant activity of methanol extract was assessed by DPPH radical scavenging and FRAP assays. Determination of enzyme inhibition activity was determined using 5-LOX inhibitory activity. Total phenolic and flavonoids contents were measured by Folin-Chicalteu and colorimeteric methods respectively. Minerals and heavy metals contents were determined using Atomic absorption spectrophotometer. Qualitative HPLC analysis were performed using some standard phenolic compounds. RESULTS: The highest phenolic (17.5 ± 2.5 mg GA equivalent/g) and flavonoids (41.3 ± 0.1 mg QE equivalent/g) concentrations were found in methanol extract, which also showed more scavenging activity of 1, 1-diphenyl-2-picrylhydrazyl and ferrous reducing power with IC = 81.2 ± 0.2 and IC = 11.2 ± 0.1 µg/ml, respectively. The methanol and chloroform extracts showed best inhibition of 5-lipoxygenase enzyme with 90.5 ± 0.7% and 66.9 ± 0.1% at 0.5 mg/ml, respectively. G. trichophylla extract was also evaluated for mineral contents (K, Na, Ca, Mg, Fe, and Cu), and for chemical profiling of heavy metals (Cr, Pb, Cd, Co, Zn, Ni and Hg). CONCLUSION: Our current findings suggest that this plant is good source of minerals and concentration of all heavy metals were within permissible limits. The results revealed that this ignored plant has great pharmaceutical and nutraceutical potential.
[Mh] Termos MeSH primário: Antioxidantes/análise
Gaultheria/química
Inibidores de Lipoxigenase/análise
Minerais/análise
[Mh] Termos MeSH secundário: Flavonoides/análise
Lipoxigenases/análise
Metais Pesados/análise
Oxirredução
Fenóis/análise
Proteínas de Plantas/análise
Feijão de Soja/enzimologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 0 (Lipoxygenase Inhibitors); 0 (Metals, Heavy); 0 (Minerals); 0 (Phenols); 0 (Plant Proteins); EC 1.13.11.- (Lipoxygenases)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170105
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-016-1511-4


  6 / 134 MEDLINE  
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[PMID]:27696021
[Au] Autor:Raya-González J; Velázquez-Becerra C; Barrera-Ortiz S; López-Bucio J; Valencia-Cantero E
[Ad] Endereço:Instituto de Investigaciones Químico-Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio B3, Ciudad Universitaria, C. P. 58030, Morelia, Michoacán, Mexico.
[Ti] Título:N,N-dimethyl hexadecylamine and related amines regulate root morphogenesis via jasmonic acid signaling in Arabidopsis thaliana.
[So] Source:Protoplasma;254(3):1399-1410, 2017 May.
[Is] ISSN:1615-6102
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:Plant growth-promoting rhizobacteria are natural inhabitants of roots, colonize diverse monocot and dicot species, and affect several functional traits such as root architecture, adaptation to adverse environments, and protect plants from pathogens. N,N-dimethyl-hexadecylamine (C16-DMA) is a rhizobacterial amino lipid that modulates the postembryonic development of several plants, likely as part of volatile blends. In this work, we evaluated the bioactivity of C16-DMA and other related N,N-dimethyl-amines with varied length and found that inhibition of primary root growth was related to the length of the acyl chain. C16-DMA inhibited primary root growth affecting cell division and elongation, while promoting lateral root formation and root hair growth and density in Arabidopsis thaliana (Arabidopsis) wild-type (WT) seedlings. Interestingly, C16-DMA induced the expression of the jasmonic acid (JA)-responsive gene marker pLOX2:uidA, while JA-related mutants jar1, coi1-1, and myc2 affected on JA biosynthesis and perception, respectively, are compromised in C16-DMA responses. Comparison of auxin-regulated gene expression, root architectural changes in WT, and auxin-related mutants aux1-7, tir1/afb2/afb3, and arf7-1/arf19-1 to C16-DMA shows that the C16-DMA effects occur independently of auxin signaling. Together, these results reveal a novel class of aminolipids modulating root organogenesis via crosstalk with the JA signaling pathway.
[Mh] Termos MeSH primário: Arabidopsis/metabolismo
Ciclopentanos/metabolismo
Metilaminas/farmacologia
Morfogênese/efeitos dos fármacos
Oxilipinas/metabolismo
Raízes de Plantas/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Arabidopsis/crescimento & desenvolvimento
Proteínas de Arabidopsis/biossíntese
Proteínas de Arabidopsis/metabolismo
Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos/metabolismo
Divisão Celular/efeitos dos fármacos
Ácidos Indolacéticos/metabolismo
Lipoxigenases/biossíntese
Metilaminas/química
Metilaminas/metabolismo
Nucleotidiltransferases/metabolismo
Raízes de Plantas/citologia
Raízes de Plantas/microbiologia
Plântulas/metabolismo
Transdução de Sinais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Arabidopsis Proteins); 0 (Basic Helix-Loop-Helix Leucine Zipper Transcription Factors); 0 (COI1 protein, Arabidopsis); 0 (Cyclopentanes); 0 (Indoleacetic Acids); 0 (MYC2 protein, Arabidopsis); 0 (Methylamines); 0 (Oxylipins); 0 (hexadecyldimethylamine); 6RI5N05OWW (jasmonic acid); EC 1.13.11.- (Lipoxygenases); EC 1.13.11.- (lipoxygenase 2, Arabidopsis); EC 2.7.7.- (JAR1 protein, Arabidopsis); EC 2.7.7.- (Nucleotidyltransferases)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE
[do] DOI:10.1007/s00709-016-1031-6


  7 / 134 MEDLINE  
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[PMID]:27631339
[Au] Autor:Deng Z; Wang ZY; Kutschera U
[Ad] Endereço:State Key Laboratory Breeding Base for Zhejiang Sustainable Pest and Disease Control, Institute of Virology and Biotechnology, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, China.
[Ti] Título:Seedling development in maize cv. B73 and blue light-mediated proteomic changes in the tip vs. stem of the coleoptile.
[So] Source:Protoplasma;254(3):1317-1322, 2017 May.
[Is] ISSN:1615-6102
[Cp] País de publicação:Austria
[La] Idioma:eng
[Ab] Resumo:In 2009, the draft genome of the reference inbred line of maize (Zea mays L. spp. mays cv. B73) was published so that, using this specific corn variety, molecular analyses of physiological processes became possible. However, the morphology and developmental patterns of B73 maize, compared with that of the more frequently used hybrid varieties, have not yet been analyzed. Here, we describe organ development in seedlings of B73 maize and in those of six other hybrid cultivars, and document significant morphological as well as quantitative differences between these varieties of Z. mays. In a second set of experiments, we used etiolated seedlings of B73 maize to analyze the effect of blue light (BL) on the patterns of proteins in the tip vs. growing region of this sheath-like organ. By using two-dimensional difference gel electrophoresis (2D DIGE), coupled with tandem mass spectrometry, we detected, in the microsomal fraction of maize coleoptile tips, rapid changes in the abundance of protein spots of maize phototropin 1 and several metabolic enzymes. In the sub-apical (growing) region of the coleoptile, proteomic changes were less pronounced. These results suggest that the tip of the coleoptile of B73 maize may serve as a unique model system for dissecting BL responses in a light-sensitive plant organ of known function.
[Mh] Termos MeSH primário: Cotilédone/metabolismo
Luz
Proteínas de Plantas/metabolismo
Caules de Planta/metabolismo
Plântulas/crescimento & desenvolvimento
Zea mays/embriologia
[Mh] Termos MeSH secundário: Quimera/crescimento & desenvolvimento
Glucosiltransferases/metabolismo
Lipoxigenases/metabolismo
Fototropinas/metabolismo
Proteoma/metabolismo
Proteômica
Plântulas/embriologia
Zea mays/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Phototropins); 0 (Plant Proteins); 0 (Proteome); EC 1.13.11.- (Lipoxygenases); EC 2.4.1.- (Glucosyltransferases); EC 2.4.1.13 (sucrose synthase)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160916
[St] Status:MEDLINE
[do] DOI:10.1007/s00709-016-1023-6


  8 / 134 MEDLINE  
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[PMID]:27827841
[Au] Autor:Deng J; Yu HJ; Li YY; Zhang XM; Liu P; Li Q; Jiang WJ
[Ad] Endereço:Key Laboratory of Horticultural Crops Genetic Improvement (Ministry of Agriculture), Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China. 115425193@163.com.
[Ti] Título:Leaf Volatile Compounds and Associated Gene Expression during Short-Term Nitrogen Deficient Treatments in Cucumis Seedlings.
[So] Source:Int J Mol Sci;17(11), 2016 Nov 02.
[Is] ISSN:1422-0067
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Nitrogen (N) is an important macronutrient for plant growth and development, but the regulatory mechanism of volatile compounds in response to N deficiency is not well understood, especially in cucumber, which consumes excessive N during growth. In this study, the major volatile compounds from cucumber leaves subjected to N deficiency were analyzed by GC-MS. A total of 24 volatile components were identified including 15 aldehydes, two ketones, two alkenes, and five other volatile compounds in 9930 leaves. Principal component analysis using volatile compounds from cucumber leaves provided good separation between N-sufficient and N-deficient treatments. The main volatiles in cucumber leaves were found to be C6 and C9 aldehydes, especially ( )-2-hexanal and ( , )-2,6-nonadienal. ( )-2-hexanal belonged to the C6 aldehyde and was the most abundant compound, whereas ( , )-2,6-nonadienal was the chief component of C9 aldehydes. During N-deficient treatment, short-chain volatile content was significantly improved at 5 day, other volatiles displayed significant reduction or no significantly changes in all sampling points. Improvement of short-chain volatiles was confirmed in the six other inbred lines at 5 day after N-deficient treatments. The expression analysis of 12 cucumber genes and two genes revealed that , , and had common up-regulated expression patterns in response to N-deficient stress in most inbred lines; meanwhile, most sample points of also had significant up-regulated expression patterns. This research focused on the relationship between volatiles in cucumber and different nitrogen environments to provide valuable insight into the effect of cultivation and management of the quality of cucumber and contributes to further research on volatile metabolism in cucumber.
[Mh] Termos MeSH primário: Cucumis sativus/efeitos dos fármacos
Regulação da Expressão Gênica de Plantas
Nitrogênio/farmacologia
Folhas de Planta/efeitos dos fármacos
Plântulas/efeitos dos fármacos
Compostos Orgânicos Voláteis/isolamento & purificação
[Mh] Termos MeSH secundário: Aldeídos/isolamento & purificação
Aldeídos/metabolismo
Alcenos/isolamento & purificação
Alcenos/metabolismo
Cucumis sativus/genética
Cucumis sativus/metabolismo
Cromatografia Gasosa-Espectrometria de Massas
Hidroliases/genética
Hidroliases/metabolismo
Cetonas/isolamento & purificação
Cetonas/metabolismo
Lipoxigenases/genética
Lipoxigenases/metabolismo
Nitrogênio/deficiência
Folhas de Planta/genética
Folhas de Planta/metabolismo
Proteínas de Plantas/genética
Proteínas de Plantas/metabolismo
Análise de Componente Principal
Plântulas/genética
Plântulas/metabolismo
Fatores de Tempo
Compostos Orgânicos Voláteis/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aldehydes); 0 (Alkenes); 0 (Ketones); 0 (Plant Proteins); 0 (Volatile Organic Compounds); EC 1.13.11.- (Lipoxygenases); EC 4.2.1.- (9-hydroperoxide lyase); EC 4.2.1.- (Hydro-Lyases); N762921K75 (Nitrogen)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170403
[Lr] Data última revisão:
170403
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161110
[St] Status:MEDLINE


  9 / 134 MEDLINE  
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[PMID]:27566837
[Au] Autor:Djouahri A; Saka B; Boudarene L; Baaliouamer A
[Ad] Endereço:Laboratory of Functional Organic Analysis, Department of Chemistry, Faculty of Chemistry, Houari Boumediene University of Sciences and Technology (USTHB), El Alia, BP 32, Bab Ezzouar, 16111, Algiers, Algeria.
[Ti] Título:Essential Oil Variability and Biological Activities of Tetraclinis articulata (Vahl) Mast. Wood According to the Extraction Time.
[So] Source:Chem Biodivers;13(12):1691-1706, 2016 Dec.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:In the present work, the hydrodistillation (HD) and microwave-assisted hydrodistillation (MAHD) kinetics of essential oil (EO) extracted from Tetraclinis articulata (Vahl) Mast. wood was conducted, in order to assess the impact of extraction time and technique on chemical composition and biological activities. Gas chromatography (GC) and GC/mass spectrometry analyses showed significant differences between the extracted EOs, where each family class or component presents a specific kinetic according to extraction time, technique and especially for the major components: camphene, linalool, cedrol, carvacrol and α-acorenol. Furthermore, our findings showed a high variability for both antioxidant and anti-inflammatory activities, where each activity has a specific effect according to extraction time and technique. The highlighted variability reflects the high impact of extraction time and technique on chemical composition and biological activities, which led to conclude that we should select EOs to be investigated carefully depending on extraction time and technique, in order to isolate the bioactive components or to have the best quality of EO in terms of biological activities and preventive effects in food.
[Mh] Termos MeSH primário: Anti-Inflamatórios/farmacologia
Antioxidantes/farmacologia
Cupressaceae/química
Inibidores Enzimáticos/farmacologia
Óleos Voláteis/isolamento & purificação
Óleos Voláteis/farmacologia
[Mh] Termos MeSH secundário: Anti-Inflamatórios/química
Anti-Inflamatórios/isolamento & purificação
Antioxidantes/química
Antioxidantes/isolamento & purificação
Relação Dose-Resposta a Droga
Inibidores Enzimáticos/química
Inibidores Enzimáticos/isolamento & purificação
Lipoxigenases/metabolismo
Óleos Voláteis/química
Relação Estrutura-Atividade
Fatores de Tempo
Xantina Oxidase/antagonistas & inibidores
Xantina Oxidase/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antioxidants); 0 (Enzyme Inhibitors); 0 (Oils, Volatile); EC 1.13.11.- (Lipoxygenases); EC 1.17.3.2 (Xanthine Oxidase)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170120
[Lr] Data última revisão:
170120
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160828
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201600124


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[PMID]:27530535
[Au] Autor:Li Y; Dicke M; Kroes A; Liu W; Gols R
[Ad] Endereço:Laboratory of Entomology, Wageningen University, P.O. Box 16, 6700 AA, Wageningen, The Netherlands.
[Ti] Título:Interactive Effects of Cabbage Aphid and Caterpillar Herbivory on Transcription of Plant Genes Associated with Phytohormonal Signalling in Wild Cabbage.
[So] Source:J Chem Ecol;42(8):793-805, 2016 Aug.
[Is] ISSN:1573-1561
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Plants are commonly attacked by a variety of insect herbivores and have developed specific defenses against different types of attackers. At the molecular level, herbivore-specific signalling pathways are activated by plants in response to attackers with different feeding strategies. Feeding by leaf-chewing herbivores predominantly activates jasmonic acid (JA)-regulated defenses, whereas feeding by phloem-sucking herbivores generally activates salicylic acid (SA)-regulated defenses. When challenged sequentially by both phloem-sucking and leaf-chewing herbivores, SA-JA antagonism may constrain the plant's ability to timely and adequately divert defense to the second herbivore that requires activation of a different defensive pathway. We investigated the effect of the temporal sequence of infestation by the aphid Brevicoryne brassicae and three caterpillar species, Plutella xylostella, Pieris brassicae, and Mamestra brassicae, on the interaction between JA and SA signal-transduction pathways in three wild cabbage populations. We found no support for SA-JA antagonism, irrespective of the temporal sequence of herbivore introduction or the identity of the caterpillar species based on the transcript levels of the JA- and SA-regulated marker genes LOX and PR-1, respectively, at the examined time points, 6, 24, and 48 h. In general, infestation with aphids alone had little effect on the transcript levels of the two marker genes, whereas the three caterpillar species upregulated not only LOX but also PR-1. Transcriptional changes were different for plants from the three different natural cabbage populations.
[Mh] Termos MeSH primário: Afídeos/fisiologia
Brassica/citologia
Genes de Plantas/genética
Herbivoria
Lepidópteros/fisiologia
Reguladores de Crescimento de Planta/metabolismo
Transcrição Genética
[Mh] Termos MeSH secundário: Animais
Brassica/genética
Regulação Enzimológica da Expressão Gênica
Regulação da Expressão Gênica de Plantas
Larva/fisiologia
Lipoxigenases/genética
Transdução de Sinais/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Growth Regulators); EC 1.13.11.- (Lipoxygenases)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160818
[St] Status:MEDLINE



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