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[PMID]: 29287121 [Au] Autor: Meyers AM; Mourra D; Beeler JA [Ad] Endereço: Department of Psychology, Queens College, City University New York, Flushing, New York, United States of America. [Ti] Título: High fructose corn syrup induces metabolic dysregulation and altered dopamine signaling in the absence of obesity. [So] Source: PLoS One;12(12):e0190206, 2017. [Is] ISSN: 1932-6203 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity, independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely accepted as a rodent model of diet-induced obesity (DIO) and metabolic disorder, the value of HFCS alone as a rodent model of DIO is unclear. Impaired dopamine function is associated with obesity and high fat diet, but the effect of HFCS on the dopamine system has not been investigated. The objective of this study was to test the effect of HFCS on weight gain, glucose regulation, and evoked dopamine release using fast-scan cyclic voltammetry. Mice (C57BL/6) received either water or 10% HFCS solution in combination with ad libitum chow for 15 weeks. HFCS consumption with chow diet did not induce weight gain compared to water, chow-only controls but did induce glucose dysregulation and reduced evoked dopamine release in the dorsolateral striatum. These data show that HFCS can contribute to metabolic disorder and altered dopamine function independent of weight gain and high-fat diets. [Mh] Termos MeSH primário: Dopamina/metabolismo Xarope de Milho Rico em Frutose/efeitos adversos Doenças Metabólicas/etiologia Transdução de Sinais [Mh] Termos MeSH secundário: Animais Peso Corporal/efeitos dos fármacos Corpo Estriado/metabolismo Feminino Glucose/metabolismo Masculino Camundongos Camundongos Endogâmicos C57BL Obesidade/metabolismo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (High Fructose Corn Syrup); IY9XDZ35W2 (Glucose); VTD58H1Z2X (Dopamine) [Em] Mês de entrada: 1802 [Cu] Atualização por classe: 180207 [Lr] Data última revisão: 180207 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 171230 [St] Status: MEDLINE [do] DOI: 10.1371/journal.pone.0190206

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[PMID]: 28676578 [Au] Autor: Barlow P; McKee M; Basu S; Stuckler D [Ad] Endereço: Department of Sociology (Barlow), University of Oxford, Oxford, UK; Department of Public Health and Policy (McKee), London School of Hygiene and Tropical Medicine, London, UK; Stanford Prevention Research Center (Basu), Stanford University, Palo Alto, Calif; Department of Policy Analysis and Public [Ti] Título: Impact of the North American Free Trade Agreement on high-fructose corn syrup supply in Canada: a natural experiment using synthetic control methods. [So] Source: CMAJ;189(26):E881-E887, 2017 Jul 04. [Is] ISSN: 1488-2329 [Cp] País de publicação: Canada [La] Idioma: eng [Ab] Resumo: BACKGROUND: Critics of free trade agreements have argued that they threaten public health, as they eliminate barriers to trade in potentially harmful products, such as sugar. Here we analyze the North American Free Trade Agreement (NAFTA), testing the hypothesis that lowering tariffs on food and beverage syrups that contain high-fructose corn syrup (HFCS) increased its use in foods consumed in Canada. METHODS: We used supply data from the Food and Agriculture Organization of the United Nations to assess changes in supply of caloric sweeteners including HFCS after NAFTA. We estimate the impact of NAFTA on supply of HFCS in Canada using an innovative, quasi-experimental methodology - synthetic control methods - that creates a control group with which to compare Canada's outcomes. Additional robustness tests were performed for sample, control groups and model specification. RESULTS: Tariff reductions in NAFTA coincided with a 41.6 (95% confidence interval 25.1 to 58.2) kilocalorie per capita daily increase in the supply of caloric sweeteners including HFCS. This change was not observed in the control groups, including Australia and the United Kingdom, as well as a composite control of 16 countries. Results were robust to placebo tests and additional sensitivity analyses. INTERPRETATION: NAFTA was strongly associated with a marked rise in HFCS supply and likely consumption in Canada. Our study provides evidence that even a seemingly modest change to product tariffs in free trade agreements can substantially alter population-wide dietary behaviour and exposure to risk factors. [Mh] Termos MeSH primário: Bebidas/análise Comércio/legislação & jurisprudência Ingestão de Energia Xarope de Milho Rico em Frutose/provisão & distribuição [Mh] Termos MeSH secundário: Canadá Análise de Alimentos Xarope de Milho Rico em Frutose/economia Seres Humanos Armazenamento e Recuperação da Informação Obesidade/epidemiologia Saúde Pública Nações Unidas Estados Unidos [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: 0 (High Fructose Corn Syrup) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 171012 [Lr] Data última revisão: 171012 [Sb] Subgrupo de revista: AIM; IM [Da] Data de entrada para processamento: 170706 [St] Status: MEDLINE [do] DOI: 10.1503/cmaj.161152

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[PMID]: 28650789 [Au] Autor: Dotsey RP; Moser EAS; Eckert GJ; Gregory RL [Ti] Título: Effects of Cola-Flavored Beverages and Caffeine on Streptococcus mutans Biofilm Formation and Metabolic Activity. [So] Source: J Clin Pediatr Dent;41(4):294-299, 2017. [Is] ISSN: 1053-4628 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To examine the effects of cola-flavored beverages and caffeine on growth and metabolism of Streptococcus mutans biofilm. This study was designed to determine if carbonated beverages or caffeine can increase S. mutans growth and biofilm formation and metabolic activity in vitro, potentially leading to increased S. mutans-associated cariogenicity in children that consume them. STUDY DESIGN: Six different cola-flavored products, plus pure caffeine, and pure high fructose corn syrup (HFCS), at different concentrations similar to those in the beverages were tested. A 16-hour culture of S. mutans was treated with different dilutions in bacteriological media. To test for the effect on biofilm formation, the biofilm was stained with crystal violet. The absorbance was determined to evaluate biofilm growth. Biofilm metabolic activity was measured based on biofilm having the ability to reduce XTT to a water-soluble orange compound. RESULTS: The inclusion of HFCS in the beverages, as well as pure HFCS, significantly enhanced bacterial biofilm formation and metabolic activity. Pure caffeine and the presence of caffeine in beverages did not significantly increase biofilm formation, but pure caffeine significantly increased metabolism, and Diet Coke had significantly greater metabolic activity than Caffeine-Free Diet Coke. CONCLUSIONS: HFCS increases both the biofilm formation and metabolism of S. mutans, and caffeine in some cases increases metabolism of S. mutans. [Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento Cafeína/farmacologia Bebidas Gaseificadas/efeitos adversos Cariogênicos/efeitos adversos Cola/efeitos adversos Xarope de Milho Rico em Frutose/farmacologia Streptococcus mutans/crescimento & desenvolvimento Streptococcus mutans/metabolismo [Mh] Termos MeSH secundário: Relação Dose-Resposta a Droga Seres Humanos Oxirredução/efeitos dos fármacos [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (High Fructose Corn Syrup); 3G6A5W338E (Caffeine) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170914 [Lr] Data última revisão: 170914 [Sb] Subgrupo de revista: D [Da] Data de entrada para processamento: 170627 [St] Status: MEDLINE [do] DOI: 10.17796/1053-4628-41.4.294

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[PMID]: 28317713 [Au] Autor: de Andrade JK; de Andrade CK; Komatsu E; Perreault H; Torres YR; da Rosa MR; Felsner ML [Ad] Endereço: Departamento de Química, Universidade Estadual do Centro-Oeste - UNICENTRO, 85040-080 Guarapuava, PR, Brazil. Electronic address: jucimarakulekdeandrade@gmail.com. [Ti] Título: A validated fast difference spectrophotometric method for 5-hydroxymethyl-2-furfural (HMF) determination in corn syrups. [So] Source: Food Chem;228:197-203, 2017 Aug 01. [Is] ISSN: 0308-8146 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Corn syrups, important ingredients used in food and beverage industries, often contain high levels of 5-hydroxymethyl-2-furfural (HMF), a toxic contaminant. In this work, an in house validation of a difference spectrophotometric method for HMF analysis in corn syrups was developed using sophisticated statistical tools by the first time. The methodology showed excellent analytical performance with good selectivity, linearity (R =99.9%, r>0.99), accuracy and low limits (LOD=0.10mgL and LOQ=0.34mgL ). An excellent precision was confirmed by repeatability (RSD (%)=0.30) and intermediate precision (RSD (%)=0.36) estimates and by Horrat value (0.07). A detailed study of method precision using a nested design demonstrated that variation sources such as instruments, operators and time did not interfere in the variability of results within laboratory and consequently in its intermediate precision. The developed method is environmentally friendly, fast, cheap and easy to implement resulting in an attractive alternative for corn syrups quality control in industries and official laboratories. [Mh] Termos MeSH primário: Óleo de Milho/análise Furaldeído/análogos & derivados Xarope de Milho Rico em Frutose/química Espectrofotometria/métodos [Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão/métodos Furaldeído/química [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (High Fructose Corn Syrup); 70ETD81LF0 (5-hydroxymethylfurfural); 8001-30-7 (Corn Oil); DJ1HGI319P (Furaldehyde) [Em] Mês de entrada: 1705 [Cu] Atualização por classe: 170501 [Lr] Data última revisão: 170501 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170321 [St] Status: MEDLINE

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[PMID]: 28243908 [Au] Autor: Kozlov VA; Sapozhnikov SP; Karyshev PB; Sheptukhina AI; Nikolaeva OV [Ad] Endereço: Department of Medical Biology with a Course of Microbiology and Virology, Cheboksary, Russia. pooh12@yandex.ru. [Ti] Título: Systemic Amyloidosis Model on Young Mice. [So] Source: Bull Exp Biol Med;162(4):520-523, 2017 Feb. [Is] ISSN: 1573-8221 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis. [Mh] Termos MeSH primário: Amiloide/ultraestrutura Amiloidose/patologia Modelos Animais de Doenças Nanopartículas/toxicidade Creme para a Pele/toxicidade [Mh] Termos MeSH secundário: Idade de Início Amiloidose/induzido quimicamente Amiloidose/metabolismo Animais Carotenoides/química Emulsificantes/química Xarope de Milho Rico em Frutose/química Injeções Subcutâneas Rim/metabolismo Rim/patologia Rim/ultraestrutura Fígado/metabolismo Fígado/patologia Fígado/ultraestrutura Masculino Camundongos Nanopartículas/administração & dosagem Dióxido de Silício/química Creme para a Pele/administração & dosagem Óleo de Soja/química Baço/metabolismo Baço/patologia Baço/ultraestrutura [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Amyloid); 0 (Emulsifying Agents); 0 (High Fructose Corn Syrup); 36-88-4 (Carotenoids); 7631-86-9 (Silicon Dioxide); 8001-22-7 (Soybean Oil) [Em] Mês de entrada: 1703 [Cu] Atualização por classe: 170315 [Lr] Data última revisão: 170315 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170301 [St] Status: MEDLINE [do] DOI: 10.1007/s10517-017-3652-y

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[PMID]: 28209058 [Au] Autor: Shintani T; Yamada T; Hayashi N; Iida T; Nagata Y; Ozaki N; Toyoda Y [Ad] Endereço: Research and Development, Matsutani Chemical Industry Company, Limited , 5-3 Kita-Itami, Itami, Hyogo 664-8508, Japan. [Ti] Título: Rare Sugar Syrup Containing d-Allulose but Not High-Fructose Corn Syrup Maintains Glucose Tolerance and Insulin Sensitivity Partly via Hepatic Glucokinase Translocation in Wistar Rats. [So] Source: J Agric Food Chem;65(13):2888-2894, 2017 Apr 05. [Is] ISSN: 1520-5118 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Ingestion of high-fructose corn syrup (HFCS) is associated with the risk of both diabetes and obesity. Rare sugar syrup (RSS) has been developed by alkaline isomerization of HFCS and has anti-obesity and anti-diabetic effects. However, the influence of RSS on glucose metabolism has not been explored. We investigated whether long-term administration of RSS maintains glucose tolerance and whether the underlying mechanism involves hepatic glucokinase translocation. Wistar rats were administered water, RSS, or HFCS in drinking water for 10 weeks and then evaluated for glucose tolerance, insulin tolerance, liver glycogen content, and subcellular distribution of liver glucokinase. RSS significantly suppressed body weight gain and abdominal fat mass (p < 0.05). The glucose tolerance test revealed significantly higher blood glucose levels in the HFCS group compared to the water group, whereas the RSS group had significantly lower blood glucose levels from 90 to 180 min (p < 0.05). At 30, 60, and 90 min, the levels of insulin in the RSS group were significantly lower than those in the water group (p < 0.05). The amount of hepatic glycogen was more than 3 times higher in the RSS group than that in the other groups. After glucose loading, the nuclear export of glucokinase was significantly increased in the RSS group compared to the water group. These results imply that RSS maintains glucose tolerance and insulin sensitivity, at least partly, by enhancing nuclear export of hepatic glucokinase. [Mh] Termos MeSH primário: Glicemia/metabolismo Frutose/análise Glucoquinase/metabolismo Xarope de Milho Rico em Frutose/análise Resistência à Insulina Fígado/enzimologia [Mh] Termos MeSH secundário: Animais Transporte Biológico Frutose/metabolismo Teste de Tolerância a Glucose Xarope de Milho Rico em Frutose/metabolismo Insulina/metabolismo Fígado/metabolismo Masculino Ratos Ratos Wistar [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Blood Glucose); 0 (High Fructose Corn Syrup); 0 (Insulin); 23140-52-5 (psicose); 30237-26-4 (Fructose); EC 2.7.1.2 (Glucokinase) [Em] Mês de entrada: 1706 [Cu] Atualização por classe: 170605 [Lr] Data última revisão: 170605 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170218 [St] Status: MEDLINE [do] DOI: 10.1021/acs.jafc.6b05627

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[PMID]: 28193326 [Au] Autor: Jia DX; Zhou L; Zheng YG [Ad] Endereço: Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, PR China; Engineering Research Center of Bioconversion and Biopurification of the Ministry of Education, Zhejiang University of Technology, Hangzhou 310014, PR China. [Ti] Título: Properties of a novel thermostable glucose isomerase mined from Thermus oshimai and its application to preparation of high fructose corn syrup. [So] Source: Enzyme Microb Technol;99:1-8, 2017 Apr. [Is] ISSN: 1879-0909 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Glucose isomerase (GI) is used in vitro to convert d-glucose to d-fructose, which is capable of commercial producing high fructose corn syrup (HFCS). To manufacture HFCS at elevated temperature and reduce the cost of enriching syrups, novel refractory GIs from Thermoanaerobacterium xylanolyticum (TxGI), Thermus oshimai (ToGI), Geobacillus thermocatenulatus (GtGI) and Thermoanaerobacter siderophilus (TsGI) were screened via genome mining approach. The enzymatic characteristics research showed that ToGI had higher catalytic efficiency and superior thermostability toward d-glucose among the screened GIs. Its optimum temperature reached 95°C and could retain more than 80% of initial activity in the presence of 20mM Mn at 85°C for 48h. The K and k /K values for ToGI were 81.46mM and 21.77min mM , respectively. Furthermore, the maximum conversion yield of 400g/L d-glucose to d-fructose at 85°C was 52.16%. Considering its excellent high thermostability and ameliorable application performance, ToGI might be promising for realization of future industrial production of HFCS at elevated temperature. [Mh] Termos MeSH primário: Aldose-Cetose Isomerases/metabolismo Proteínas de Bactérias/metabolismo Xarope de Milho Rico em Frutose/isolamento & purificação Thermus/enzimologia [Mh] Termos MeSH secundário: Aldose-Cetose Isomerases/genética Sequência de Aminoácidos Proteínas de Bactérias/genética Biotecnologia Estabilidade Enzimática Tecnologia de Alimentos Frutose/biossíntese Geobacillus/enzimologia Geobacillus/genética Glucose/metabolismo Temperatura Alta Concentração de Íons de Hidrogênio Microbiologia Industrial Cinética Proteínas Recombinantes/genética Proteínas Recombinantes/metabolismo Homologia de Sequência de Aminoácidos Thermoanaerobacter/enzimologia Thermoanaerobacter/genética Thermoanaerobacterium/enzimologia Thermoanaerobacterium/genética Thermus/genética [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Bacterial Proteins); 0 (High Fructose Corn Syrup); 0 (Recombinant Proteins); 30237-26-4 (Fructose); EC 5.3.1.- (Aldose-Ketose Isomerases); EC 5.3.1.5 (xylose isomerase); IY9XDZ35W2 (Glucose) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170724 [Lr] Data última revisão: 170724 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 170215 [St] Status: MEDLINE

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[PMID]: 27824430 [Au] Autor: Pektas MB; Yücel G; Koca HB; Sadi G; Yildirim OG; Öztürk G; Akar F [Ad] Endereço: Faculty of Medicine, Department of Medical Pharmacology, Afyon Kocatepe University, Afyonkarahisar, Turkey. [Ti] Título: Dietary Fructose-Induced Hepatic Injury in Male and Female Rats: Influence of Resveratrol. [So] Source: Drug Res (Stuttg);67(2):103-110, 2017 Feb. [Is] ISSN: 2194-9387 [Cp] País de publicação: Germany [La] Idioma: eng [Ab] Resumo: Relatively little is known about gender-dependent susceptibility to hepatic injury induced by nutritional factors. In the current study, we investigated dietary fructose-induced hepatic degeneration and roles of endothelial nitric oxide synthase (eNOS), insulin receptor (IRß) and substrate-1 (IRS-1) expressions in association with inflammatory markers in male and female rats. Moreover, we examined potential effect of resveratrol on fructose-induced changes. Male and female rats were divided into 4 groups as control, resveratrol, fructose and resveratrol plus fructose. All rats were fed with a standard diet with or without resveratrol (500 mg/kg). Fructose was given as 10% in drinking waterfor 24 weeks. Long-term dietary fructose caused parenchymal degeneration and hyperemia in association with impaired eNOS mRNA/protein expressions in liver of male and female rats. This dietary intervention also led to increases in hepatic triglyceride content, TNFα and IL-1ß levels in both genders. Gender-related differences to consequence of fructose consumption were not obvious. Resveratrol supplementation markedly attenuated hepatic degeneration, hyperemia and triglyceride content in association with reduced TNFα and IL-1ß levels, but enhanced IRß mRNA and IRS-1 protein, in male and female rats upon fructose feeding. Long-term dietary fructose causes hepatic degeneration possibly via a decrease in eNOS, but increase in TNFα and IL-1ß, in both genders. Resveratrol supplementation improved fructose-induced hepatic injury. [Mh] Termos MeSH primário: Antioxidantes/farmacologia Dieta da Carga de Carboidratos/efeitos adversos Frutose/efeitos adversos Fígado/efeitos dos fármacos Óxido Nítrico Sintase Tipo III/metabolismo Hepatopatia Gordurosa não Alcoólica/induzido quimicamente Hepatopatia Gordurosa não Alcoólica/enzimologia Estilbenos/farmacologia [Mh] Termos MeSH secundário: Animais Antioxidantes/administração & dosagem Biomarcadores/sangue Peso Corporal/efeitos dos fármacos Feminino Frutose/administração & dosagem Xarope de Milho Rico em Frutose/administração & dosagem Xarope de Milho Rico em Frutose/efeitos adversos Insulina/metabolismo Proteínas Substratos do Receptor de Insulina/metabolismo Interleucina-1beta/metabolismo Fígado/enzimologia Fígado/patologia Masculino Hepatopatia Gordurosa não Alcoólica/patologia Ratos Ratos Wistar Receptor de Insulina/metabolismo Transdução de Sinais Estilbenos/administração & dosagem Triglicerídeos/metabolismo Fator de Necrose Tumoral alfa/metabolismo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Antioxidants); 0 (Biomarkers); 0 (High Fructose Corn Syrup); 0 (IL1B protein, rat); 0 (Insulin); 0 (Insulin Receptor Substrate Proteins); 0 (Interleukin-1beta); 0 (Irs1 protein, rat); 0 (Stilbenes); 0 (Triglycerides); 0 (Tumor Necrosis Factor-alpha); 30237-26-4 (Fructose); EC 1.14.13.39 (Nitric Oxide Synthase Type III); EC 1.14.13.39 (Nos3 protein, rat); EC 2.7.10.1 (Receptor, Insulin); Q369O8926L (resveratrol) [Em] Mês de entrada: 1703 [Cu] Atualização por classe: 170308 [Lr] Data última revisão: 170308 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161109 [St] Status: MEDLINE [do] DOI: 10.1055/s-0042-118386

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[PMID]: 27719903 [Au] Autor: Li S; Zhang X; Shan Y; Su D; Ma Q; Wen R; Li J [Ad] Endereço: College of Science, Central South University of Forestry and Technology, Changsha 410004, China. [Ti] Título: Qualitative and quantitative detection of honey adulterated with high-fructose corn syrup and maltose syrup by using near-infrared spectroscopy. [So] Source: Food Chem;218:231-236, 2017 Mar 01. [Is] ISSN: 0308-8146 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Near-infrared spectroscopy (NIR) was used for qualitative and quantitative detection of honey adulterated with high-fructose corn syrup (HFCS) or maltose syrup (MS). Competitive adaptive reweighted sampling (CARS) was employed to select key variables. Partial least squares linear discriminant analysis (PLS-LDA) was adopted to classify the adulterated honey samples. The CARS-PLS-LDA models showed an accuracy of 86.3% (honey vs. adulterated honey with HFCS) and 96.1% (honey vs. adulterated honey with MS), respectively. PLS regression (PLSR) was used to predict the extent of adulteration in the honeys. The results showed that NIR combined with PLSR could not be used to quantify adulteration with HFCS, but could be used to quantify adulteration with MS: coefficient (R ) and root mean square of prediction (RMSEP) were 0.901 and 4.041 for MS-adulterated samples from different floral origins, and 0.981 and 1.786 for MS-adulterated samples from the same floral origin (Brassica spp.), respectively. [Mh] Termos MeSH primário: Contaminação de Alimentos/análise Xarope de Milho Rico em Frutose/análise Mel/análise Maltose/análise Espectroscopia de Luz Próxima ao Infravermelho/métodos [Mh] Termos MeSH secundário: Análise Discriminante Xarope de Milho Rico em Frutose/química Análise dos Mínimos Quadrados Modelos Lineares Maltose/química [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (High Fructose Corn Syrup); 69-79-4 (Maltose) [Em] Mês de entrada: 1701 [Cu] Atualização por classe: 171008 [Lr] Data última revisão: 171008 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161011 [St] Status: MEDLINE

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[PMID]: 27892935 [Au] Autor: DeChristopher LR; Uribarri J; Tucker KL [Ad] Endereço: NY Medical College, Valhalla, NY, USA. [Ti] Título: The link between soda intake and asthma: science points to the high-fructose corn syrup, not the preservatives: a commentary. [So] Source: Nutr Diabetes;6(11):e234, 2016 Nov 28. [Is] ISSN: 2044-4052 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: Recent research conducted by investigators at the National Center for Chronic Disease Prevention and Health Promotion-a division of the US Centers for Disease Control and Prevention (CDC)-found that 'Regular-Soda Intake, Independent of Weight Status, is Associated with Asthma among US High School Students.' On the basis of their review of prior studies, researchers hypothesized that the association may be due to high intake of sodium benzoate, a commonly used preservative in US soft drinks. But a closer look at these prior research studies suggests that there is no strong scientific evidence that the preservatives in US soft drinks are associated with asthma. Importantly, other recent research suggests that the association may be with the unpaired (excess free) fructose in high fructose corn syrup. [Mh] Termos MeSH primário: Asma/etiologia Bebidas Gaseificadas/efeitos adversos Xarope de Milho Rico em Frutose/efeitos adversos [Mh] Termos MeSH secundário: Medicina Baseada em Evidências Conservantes de Alimentos/efeitos adversos Seres Humanos [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Food Preservatives); 0 (High Fructose Corn Syrup) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170915 [Lr] Data última revisão: 170915 [Sb] Subgrupo de revista: IM [Da] Data de entrada para processamento: 161129 [St] Status: MEDLINE [do] DOI: 10.1038/nutd.2016.46

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1			PalavrasDescritor de assuntoDescritor de assunto primárioLimitesAutorPalavras do títuloPalavras do resumoIdiomaPaís de publicaçãoNome de substânciaNome de pessoa como assuntoRevistaAssunto de RevistaISSNTipo de publicaçãoIdentificador únicoMês de entradaAno de publicaçãoTexto completoAtualização por classeCategoria DeCSCategoria DeCS explodidaCategoria CID-10SubSetsPais de AfiliaçãoAfiliaçãoAfiliação 2
2	and or and not		PalavrasDescritor de assuntoDescritor de assunto primárioLimitesAutorPalavras do títuloPalavras do resumoIdiomaPaís de publicaçãoNome de substânciaNome de pessoa como assuntoRevistaAssunto de RevistaISSNTipo de publicaçãoIdentificador únicoMês de entradaAno de publicaçãoTexto completoAtualização por classeCategoria DeCSCategoria DeCS explodidaCategoria CID-10SubSetsPais de AfiliaçãoAfiliaçãoAfiliação 2
3	and or and not		PalavrasDescritor de assuntoDescritor de assunto primárioLimitesAutorPalavras do títuloPalavras do resumoIdiomaPaís de publicaçãoNome de substânciaNome de pessoa como assuntoRevistaAssunto de RevistaISSNTipo de publicaçãoIdentificador únicoMês de entradaAno de publicaçãoTexto completoAtualização por classeCategoria DeCSCategoria DeCS explodidaCategoria CID-10SubSetsPais de AfiliaçãoAfiliaçãoAfiliação 2

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