Base de dados : MEDLINE
Pesquisa : D09.947.875.465.200 [Categoria DeCS]
Referências encontradas : 417 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 42 ir para página                         

  1 / 417 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28780271
[Au] Autor:Dikshit PK; Padhi SK; Moholkar VS
[Ad] Endereço:Department of Chemical Engineering, Indian Institute of Technology Guwahati, Guwahati 781 039, Assam, India.
[Ti] Título:Process optimization and analysis of product inhibition kinetics of crude glycerol fermentation for 1,3-Dihydroxyacetone production.
[So] Source:Bioresour Technol;244(Pt 1):362-370, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In present study, statistical optimization of biodiesel-derived crude glycerol fermentation to DHA by immobilized G. oxydans cells over polyurethane foam is reported. Effect of DHA (product) inhibition on crude glycerol fermentation was analyzed using conventional biokinetic models and new model that accounts for both substrate and product inhibition. Optimum values of fermentation parameters were: pH=4.7, temperature=31°C, initial substrate concentration=20g/L. At optimum conditions, DHA yield was 89% (17.83g/L). Effect of product inhibition on fermentation was trivial for DHA concentrations ≤30g/L. At higher concentrations (≥50g/L), kinetics and yield of fermentation showed marked reduction with sharp drop in V and K values. Inhibition effect was more pronounced for immobilized cells due to restricted transport of fermentation mixture across polyurethane foam. Retention of fermentation mixture in immobilized matrix resulted in higher localized DHA concentration that possibly enhanced inhibition effect.
[Mh] Termos MeSH primário: Di-Hidroxiacetona
Fermentação
Glicerol
[Mh] Termos MeSH secundário: Gluconobacter oxydans
Cinética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
O10DDW6JOO (Dihydroxyacetone); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171106
[Lr] Data última revisão:
171106
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170807
[St] Status:MEDLINE


  2 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28490123
[Au] Autor:Grainger MNC; Owens A; Manley-Harris M; Lane JR; Field RJ
[Ad] Endereço:Chemistry, School of Science University of Waikato, Private Bag 3105, Hamilton, New Zealand.
[Ti] Título:Kinetics of conversion of dihydroxyacetone to methylglyoxal in New Zealand manuka honey: Part IV - Formation of HMF.
[So] Source:Food Chem;232:648-655, 2017 Oct 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:During a study of the conversion of dihydroxyacetone (DHA) to methylglyoxal (MGO) in maturing New Zealand manuka honey, the kinetics of formation of 5-(hydroxymethyl)furfural (HMF) was studied at temperatures from 4 to 37°C. Formation of HMF was first-order during an induction period and zero-order thereafter indicating that the mechanism includes the formation of certain critical intermediates and that these require time to build up; the duration of the induction period depended primarily upon temperature. The zero-order rate constant at 37°C was the same for manuka honey and clover honey doped with 2000 or 10,000mg/kg DHA and for artificial honey with 2000mg/kg of DHA and either alanine or proline and alanine added. Zero-order rate constants for artificial honey with added amino acids were less than for a control without amino acids. A simulation was created to predict the formation of HMF over time at 37°C in manuka honey.
[Mh] Termos MeSH primário: Di-Hidroxiacetona
Mel
Aldeído Pirúvico
[Mh] Termos MeSH secundário: Cinética
Leptospermum
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
722KLD7415 (Pyruvaldehyde); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170731
[Lr] Data última revisão:
170731
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170512
[St] Status:MEDLINE


  3 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28415841
[Au] Autor:Hellwig M; Rückriemen J; Sandner D; Henle T
[Ad] Endereço:Chair of Food Chemistry, Technische Universität Dresden , D-01062 Dresden, Germany.
[Ti] Título:Unique Pattern of Protein-Bound Maillard Reaction Products in Manuka (Leptospermum scoparium) Honey.
[So] Source:J Agric Food Chem;65(17):3532-3540, 2017 May 03.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:As a unique feature, honey from the New Zealand manuka tree (Leptospermum scoparium) contains substantial amounts of dihydroxyacetone (DHA) and methylglyoxal (MGO). Although MGO is a reactive intermediate in the Maillard reaction, very little is known about reactions of MGO with honey proteins. We hypothesized that the abundance of MGO should result in a particular pattern of protein-bound Maillard reaction products (MRPs) in manuka honey. A protein-rich high-molecular-weight fraction was isolated from 12 manuka and 8 non-manuka honeys and hydrolyzed enzymatically. By HPLC-MS/MS, 8 MRPs, namely, N-ε-fructosyllysine, N-ε-maltulosyllysine, carboxymethyllysine, carboxyethyllysine (CEL), pyrraline, formyline, maltosine, and methylglyoxal-derived hydroimidazolone 1 (MG-H1), were quantitated. Compared to non-manuka honeys, the manuka honeys were characterized by high concentrations of CEL and MG-H1, whereas the formation of N-ε-fructosyllysine was suppressed, indicating concurrence reactions of glucose and MGO at the ε-amino group of protein-bound lysine. Up to 31% of the lysine and 8% of the arginine residues, respectively, in the manuka honey protein can be modified to CEL and MG-H1, respectively. CEL and MG-H1 concentrations correlated strongly with the MGO concentration of the honeys. Manuka honey possesses a special pattern of protein-bound MRPs, which might be used to prove the reliability of labeled MGO levels in honeys and possibly enable the detection of fraudulent MGO or DHA addition to honey.
[Mh] Termos MeSH primário: Di-Hidroxiacetona/química
Mel/análise
Leptospermum/química
Proteínas de Plantas/química
Aldeído Pirúvico/química
[Mh] Termos MeSH secundário: Flores/química
Reação de Maillard
Ligação Proteica
Espectrometria de Massas em Tandem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Proteins); 722KLD7415 (Pyruvaldehyde); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170608
[Lr] Data última revisão:
170608
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b00797


  4 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28407946
[Au] Autor:Rückriemen J; Klemm O; Henle T
[Ad] Endereço:Institute of Food Chemistry, Technische Universität Dresden, D-01062 Dresden, Germany.
[Ti] Título:Manuka honey (Leptospermum scoparium) inhibits jack bean urease activity due to methylglyoxal and dihydroxyacetone.
[So] Source:Food Chem;230:540-546, 2017 Sep 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Manuka honey (Leptospermum scoparium) exerts a strong antibacterial effect. Bacterial enzymes are an important target for antibacterial compounds. The enzyme urease produces ammonia and enables bacteria to adapt to an acidic environment. A new enzymatic assay, based on photometric detection of ammonia with ninhydrin, was developed to study urease activity. Methylglyoxal (MGO) and its precursor dihydroxyacetone (DHA), which are naturally present in manuka honey, were identified as jack bean urease inhibitors with IC values of 2.8 and 5.0mM, respectively. Urease inhibition of manuka honey correlates with its MGO and DHA content. Non-manuka honeys, which lack MGO and DHA, showed significantly less urease inhibition. MGO depletion from manuka honey with glyoxalase reduced urease inhibition. Therefore, urease inhibition by manuka honey is mainly due to MGO and DHA. The results obtained with jack bean urease as a model urease, may contribute to the understanding of bacterial inhibition by manuka honey.
[Mh] Termos MeSH primário: Di-Hidroxiacetona/química
Mel/análise
Aldeído Pirúvico/química
Urease/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
722KLD7415 (Pyruvaldehyde); EC 3.5.1.5 (Urease); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170630
[Lr] Data última revisão:
170630
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170415
[St] Status:MEDLINE


  5 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28279907
[Au] Autor:Hu ZC; Tian SY; Ruan LJ; Zheng YG
[Ad] Endereço:Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, PR China.
[Ti] Título:Repeated biotransformation of glycerol to 1,3-dihydroxyacetone by immobilized cells of Gluconobacter oxydans with glycerol- and urea-feeding strategy in a bubble column bioreactor.
[So] Source:Bioresour Technol;233:144-149, 2017 Jun.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Some inorganic nitrogen sources and amino acids instead of yeast extract, which resulted in trouble of product purification, were introduced for 1,3-dihydroxyacetone (DHA) production by biotransformation with Gluconobacter oxydans. The results showed that urea is an optimal nitrogen source. Furthermore, the effects of glycerol- and urea-feeding strategies for DHA production by immobilized cells in a home-made bubble column bioreactor were optimized. Cells immobilization was prepared by cultivation in the bioreactor packed with porous ceramics, and then the broth was removed. Then, repeated biotransformation by continuous-feeding of glycerol and urea was developed. Up to 96.4±4.1g/L of average DHA concentration with 94.8±2.2% of average conversion rate of glycerol to DHA was achieved after 12 cycles of run. Near colorless DHA solution with few impurities was obtained and the production cost could be decreased.
[Mh] Termos MeSH primário: Di-Hidroxiacetona/biossíntese
Gluconobacter oxydans/metabolismo
[Mh] Termos MeSH secundário: Reatores Biológicos
Biotransformação
Células Imobilizadas/metabolismo
Glicerol/metabolismo
Ureia/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
8W8T17847W (Urea); O10DDW6JOO (Dihydroxyacetone); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170605
[Lr] Data última revisão:
170605
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170311
[St] Status:MEDLINE


  6 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27664696
[Au] Autor:Spiteri M; Rogers KM; Jamin E; Thomas F; Guyader S; Lees M; Rutledge DN
[Ad] Endereço:Eurofins Analytics France, Rue Pierre Adolphe Bobierre, B.P. 42301, F-44323 NANTES Cedex 3, France.
[Ti] Título:Combination of 1H NMR and chemometrics to discriminate manuka honey from other floral honey types from Oceania.
[So] Source:Food Chem;217:766-772, 2017 Feb 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Manuka honey is a product produced essentially in New Zealand, and has been widely recognised for its antibacterial properties and specific taste. In this study, 264 honeys from New Zealand and Australia were analysed using proton NMR spectroscopy coupled with chemometrics. Known manuka markers, methylglyoxal and dihydroxyacetone, have been characterised and quantified, together with a new NMR marker, identified as being leptosperin. Manuka honey profiling using 1H NMR is shown to be a possible alternative to chromatography with the added advantage that it can measure methylglyoxal (MGO), dihydroxyacetone (DHA) and leptosperin simultaneously. By combining the information from these three markers, we established a model to estimate the proportion of manuka in a given honey. Markers of other botanical origins were also identified, which makes 1H NMR a convenient and efficient tool, complementary to pollen analysis, to control the botanical origin of Oceania honeys.
[Mh] Termos MeSH primário: Flores/química
Mel/análise
Espectroscopia de Prótons por Ressonância Magnética/métodos
[Mh] Termos MeSH secundário: Austrália
Di-Hidroxiacetona/química
Análise Discriminante
Flores/classificação
Modelos Teóricos
Nova Zelândia
Oceania
Aldeído Pirúvico/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
722KLD7415 (Pyruvaldehyde); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170902
[Lr] Data última revisão:
170902
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160925
[St] Status:MEDLINE


  7 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28256464
[Au] Autor:Rashedinia M; Jamshidzadeh A; Mehrabadi AR; Niknahad H
[Ad] Endereço:Department of Pharmacology & Toxicology, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
[Ti] Título:Prevention of phosphine-induced cytotoxicity by nutrients in HepG2 cells.
[So] Source:Indian J Med Res;144(4):560-565, 2016 Oct.
[Is] ISSN:0971-5916
[Cp] País de publicação:India
[La] Idioma:eng
[Ab] Resumo:BACKGROUND & OBJECTIVES: Phosphides used as an insecticide and rodenticide, produce phosphine (PH3) which causes accidental and intentional poisoning cases and deaths. There is no specific treatment or antidote available for PH3poisoning. It is suggested that PH3-induced toxicity is associated with adenosine triphosphate (ATP) depletion; therefore, in this study the effect of some nutrients was evaluated on PH3cytotoxicity in a cell culture model. METHODS: PH3was generated from reaction of zinc phosphide (10 mM) with water in the closed culture medium of HepG2 cells, and cytotoxicity was measured after one and three hours of incubation. ATP, glutathione (GSH) and lipid peroxidation were also assessed at one or three hours post-incubation. ATP suppliers including dihydroxyacetone, glyceraldehyde and fructose were added to the culture medium 10 min before PH3generation to prevent or reduce phosphine-induced cytotoxicity. RESULTS: Phosphine caused about 30 and 66 per cent cell death at one and three hours of incubation, respectively. ATP content of the cells was depleted to 14.7 per cent of control at one hour of incubation. ATP suppliers were able to prevent cytotoxicity and ATP depletion induced by PH3. Dihydroxyacetone, α-ketoglutarate, fructose and mannitol restored the ATP content of the cells from 14.7 per cent to about 40 , 34 , 32 and 30 per cent, respectively. Lipid peroxidation and GSH depletion were not significantly induced by zinc phosphide in this study. INTERPRETATION & CONCLUSIONS: The results supported the hypothesis that phosphine-induced cytotoxicity was due to decrease of ATP levels. ATP suppliers could prevent its toxicity by generating ATP through glycolysis. α-keto compounds such as dihydroxyacetone and α-ketoglutarate may bind to phosphine and restore mitochondrial respiration.
[Mh] Termos MeSH primário: Trifosfato de Adenosina/metabolismo
Morte Celular/efeitos dos fármacos
Células Hep G2/efeitos dos fármacos
Fosfinas/toxicidade
[Mh] Termos MeSH secundário: Sobrevivência Celular/efeitos dos fármacos
Di-Hidroxiacetona/farmacologia
Frutose/farmacologia
Glutationa/metabolismo
Seres Humanos
Ácidos Cetoglutáricos/farmacologia
Peroxidação de Lipídeos/efeitos dos fármacos
Fígado/efeitos dos fármacos
Fígado/metabolismo
Manitol/farmacologia
Mitocôndrias/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Ketoglutaric Acids); 0 (Phosphines); 30237-26-4 (Fructose); 3OWL53L36A (Mannitol); 8ID597Z82X (alpha-ketoglutaric acid); 8L70Q75FXE (Adenosine Triphosphate); FW6947296I (phosphine); GAN16C9B8O (Glutathione); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170623
[Lr] Data última revisão:
170623
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.4103/0971-5916.200896


  8 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:28095563
[Au] Autor:Graves MS; Lloyd AA; Ross EV
[Ti] Título:Defining the Absorption Spectrum of the Skin After Application of a Popular Sunless Tanner, Dihydroxyacetone, Using Re ectance Photospectrometry.
[So] Source:J Drugs Dermatol;15(11):1459-1460, 2016 Nov 01.
[Is] ISSN:1545-9616
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Dihydroxyacetone (DHA) is a popular ingredient in sunless tanner and lotions. We sought to measure the absorption spectrum of hu- man skin after application of DHA. A male in his 30's applied DHA to one underarm once daily for seven days. Re ectance spectropho- tometry was performed on the treated and untreated side. The area treated with DHA revealed increased absorption in the 400-700 nm range. Compared to normal skin, the absorption spectrum of human skin after application of DHA is altered from 400-700 nm. Care should be taking with using lasers in these wavelengths on skin treated with DHA. J Drugs Dermatol. 2016;15(11):1459-1460..
[Mh] Termos MeSH primário: Di-Hidroxiacetona/administração & dosagem
Absorção Cutânea/efeitos dos fármacos
Creme para a Pele/administração & dosagem
Pigmentação da Pele/efeitos dos fármacos
Espectrofotometria/métodos
[Mh] Termos MeSH secundário: Administração Tópica
Adulto
Cosméticos/administração & dosagem
Seres Humanos
Masculino
Pele/efeitos dos fármacos
Absorção Cutânea/fisiologia
Pigmentação da Pele/fisiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cosmetics); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170524
[Lr] Data última revisão:
170524
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE


  9 / 417 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28030589
[Au] Autor:Cokcetin NN; Pappalardo M; Campbell LT; Brooks P; Carter DA; Blair SE; Harry EJ
[Ad] Endereço:The ithree institute, University of Technology Sydney, Sydney, NSW, Australia.
[Ti] Título:The Antibacterial Activity of Australian Leptospermum Honey Correlates with Methylglyoxal Levels.
[So] Source:PLoS One;11(12):e0167780, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Most commercially available therapeutic honey is derived from flowering Leptospermum scoparium (manuka) plants from New Zealand. Australia has more than 80 Leptospermum species, and limited research to date has found at least some produce honey with high non-peroxide antibacterial activity (NPA) similar to New Zealand manuka, suggesting Australia may have a ready supply of medical-grade honey. The activity of manuka honey is largely due to the presence of methylglyoxal (MGO), which is produced non-enzymatically from dihydroxyacetone (DHA) present in manuka nectar. The aims of the current study were to chemically quantify the compounds contributing to antibacterial activity in a collection of Australian Leptospermum honeys, to assess the relationship between MGO and NPA in these samples, and to determine whether NPA changes during honey storage. Eighty different Leptospermum honey samples were analysed, and therapeutically useful NPA was seen in samples derived from species including L. liversidgei and L. polygalifolium. Exceptionally high levels of up to 1100 mg/kg MGO were present in L. polygalifolium honey samples sourced from the Northern Rivers region in NSW and Byfield, QLD, with considerable diversity among samples. There was a strong positive relationship between NPA and MGO concentration, and DHA was present in all of the active honey samples, indicating a potential for ongoing conversion to MGO. NPA was stable, with most samples showing little change following seven years of storage in the dark at 4°C. This study demonstrates the potential for Australian Leptospermum honey as a wound care product, and argues for an extension of this analysis to other Leptospermum species.
[Mh] Termos MeSH primário: Antibacterianos/química
Antibacterianos/farmacologia
Mel/análise
Leptospermum/química
Aldeído Pirúvico/análise
[Mh] Termos MeSH secundário: Di-Hidroxiacetona/análise
Relação Estrutura-Atividade
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Bacterial Agents); 722KLD7415 (Pyruvaldehyde); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170706
[Lr] Data última revisão:
170706
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161229
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0167780


  10 / 417 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:27876710
[Au] Autor:Lin X; Liu S; Xie G; Chen J; Li P; Chen J
[Ad] Endereço:School of Life Science and Technology, China Pharmaceutical University, Nanjing 210009, China.
[Ti] Título:Enhancement of 1,3-Dihydroxyacetone Production from by Combined Mutagenesis.
[So] Source:J Microbiol Biotechnol;26(11):1908-1917, 2016 Nov 28.
[Is] ISSN:1738-8872
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:Wild strain L-6 was subjected to combined mutagenesis, including UV irradiation, atmospheric and room temperature plasma, and ion beam implantation, to increase the yield of 1,3-dihydroxyacetone (DHA). With application of a high-throughput screening method, mutant I-2-239 with a DHA productivity of 103.5 g/l in flask-shake fermentation was finally obtained with the starting glycerol concentration of 120 g/l, which was 115.7% higher than the wild strain. The cultivation time also decreased from 54 h to 36 h. Compared with the wild strain, a dramatic increase in enzyme activity was observed for the mutant strain, although the increase in biomass was limited. DNA and amino acid sequence alignment revealed 11 nucleotide substitutions and 10 amino acid substitutions between the of strains L-6 and I-2-239. Simulation of the 3-D structure and prediction of active site residues and PQQ binding site residues suggested that these mutations were mainly related to PQQ binding, which was speculated to be favorable for the catalyzing capacity of glycerol dehydrogenase. RT-qPCR assay indicated that the transcription levels of and in the mutant strain were respectively 4.8-fold and 5.4-fold higher than that in the wild strain, suggesting another possible reason for the increased DHA productivity of the mutant strain.
[Mh] Termos MeSH primário: Di-Hidroxiacetona/biossíntese
Gluconobacter oxydans/genética
Gluconobacter oxydans/metabolismo
[Mh] Termos MeSH secundário: Proteínas de Bactérias/genética
Proteínas de Bactérias/metabolismo
Fermentação
Gluconobacter oxydans/enzimologia
Mutagênese
Mutação
Desidrogenase do Álcool de Açúcar/genética
Desidrogenase do Álcool de Açúcar/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Bacterial Proteins); EC 1.1.- (Sugar Alcohol Dehydrogenases); EC 1.1.1.6 (glycerol dehydrogenase); O10DDW6JOO (Dihydroxyacetone)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170308
[Lr] Data última revisão:
170308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161124
[St] Status:MEDLINE
[do] DOI:10.4014/jmb.1604.04019



página 1 de 42 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde