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[PMID]:28554628
[Au] Autor:Nieva-Echevarría B; Goicoechea E; Guillén MD
[Ad] Endereço:Food Technology, Faculty of Pharmacy, Lascaray Research Center, University of the Basque Country (UPV/EHU), Paseo de la Universidad n° 7, 01006 Vitoria-Gasteiz, Spain.
[Ti] Título:Effect of the presence of protein on lipolysis and lipid oxidation occurring during in vitro digestion of highly unsaturated oils.
[So] Source:Food Chem;235:21-33, 2017 Nov 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The effect of the presence of ovalbumin and soy protein isolate on lipolysis and oxidation taking place during in vitro gastrointestinal digestion of slightly oxidized sunflower and flaxseed oils was addressed. The extent of lipolysis, the molar proportions of acyl groups/fatty acids after digestion, and the oxidation products formed were studied by Proton Nuclear Magnetic Resonance. The presence of proteins provoked a higher hydrolysis in triglycerides, a lower decrease of polyunsaturated chains, and a lower generation of oxidation compounds (conjugated dienes in chains having also hydroperoxy/hydroxy groups, epoxides and aldehydes); the formation of hydroxides was clearly favoured over that of hydroperoxides. Study of headspace composition by Solid Phase Microextraction-Gas Chromatography/Mass Spectrometry confirmed that oxidation advanced to a lesser extent in the presence of protein. Thus, amino acids/peptides released during digestion may show antioxidant properties, affecting not only the extent of lipid oxidation, but also reactions pathways.
[Mh] Termos MeSH primário: Digestão/fisiologia
Lipólise
Ovalbumina/farmacologia
Proteínas de Soja/farmacologia
[Mh] Termos MeSH secundário: Gorduras Insaturadas
Cromatografia Gasosa-Espectrometria de Massas
Oxirredução
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fats, Unsaturated); 0 (Soybean Proteins); 9006-59-1 (Ovalbumin)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE


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[PMID]:28515160
[Au] Autor:Maki KC; Palacios OM; Lindner E; Nieman KM; Bell M; Sorce J
[Ad] Endereço:Midwest Biomedical Research/Center for Metabolic and Cardiovascular Health, Glen Ellyn, IL; and kmaki@mbclinicalresearch.com.
[Ti] Título:Replacement of Refined Starches and Added Sugars with Egg Protein and Unsaturated Fats Increases Insulin Sensitivity and Lowers Triglycerides in Overweight or Obese Adults with Elevated Triglycerides.
[So] Source:J Nutr;147(7):1267-1274, 2017 Jul.
[Is] ISSN:1541-6100
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hypertriglyceridemia is a common condition in the United States and is often associated with other metabolic disturbances, including insulin resistance, metabolic syndrome, and a predominance of small dense LDL particles. The objective of this trial was to evaluate the effects of a combination of egg protein (Epro) and unsaturated fatty acids (UFAs) substituted for refined starches and added sugars on insulin sensitivity (primary outcome) and other cardiometabolic health markers in overweight or obese adults with elevated triglyceride (TG) concentrations. Subjects with elevated TG concentrations were given test foods prepared by using Epro powder (∼8% of energy) and vegetable oil (∼8% of energy; Epro and UFA condition) or test foods prepared by using refined starch and sugar (∼16% of energy; carbohydrate condition) in a randomized, double-blind, controlled-feeding, crossover trial (3 wk/condition, 2-wk washout). The Matsuda insulin sensitivity index (MISI), fasting lipids, and other cardiometabolic health markers were assessed at baseline and the end of each diet condition. Responses were compared by using repeated-measures ANCOVA. Twenty-five participants [11 men, 14 women; mean ± SEM: age, 46.3 ± 2.4 y; body mass index (in kg/m ), 31.8 ± 1.0] with a median (interquartile range limits) fasting serum TG concentration of 173 mg/dL (159, 228 mg/dL) completed the trial. The MISI value increased 18.1% ± 8.7% from baseline during the Epro and UFA condition and decreased 5.7% ± 6.2% from baseline during the carbohydrate condition ( < 0.001). The disposition index increased 23.8% ± 20.8% during the Epro and UFA condition compared with a decrease of 16.3% ± 18.8% during carbohydrate ( = 0.042) and LDL peak particle size increased 0.12 nm (-0.12, 0.28 nm) with Epro and UFA compared with a decrease of 0.15 nm (-0.33, 0.12 nm) with carbohydrate ( = 0.019). TG and VLDL cholesterol concentrations were lowered by 18.5% (-35.7%, -6.9%) and 18.6% (-34.8%, -7.4%), respectively, after the Epro and UFA condition and by 2.5% (-13.4%, 17.0%) and 3.6% (-12.5%, 16.2%), respectively, after the carbohydrate diet condition ( < 0.002). The replacement of refined carbohydrates with a combination of Epro and UFA increased the MISI value and altered several markers of cardiometabolic health in overweight or obese adults with elevated TG concentrations. This trial was registered at clinicaltrials.gov as NCT02924558.
[Mh] Termos MeSH primário: Carboidratos/química
Proteínas do Ovo/farmacologia
Gorduras Insaturadas/farmacologia
Resistência à Insulina/fisiologia
Sobrepeso/sangue
Triglicerídeos/sangue
[Mh] Termos MeSH secundário: Adulto
Idoso
Dieta
Carboidratos da Dieta/administração & dosagem
Gorduras na Dieta/administração & dosagem
Proteínas na Dieta/administração & dosagem
Método Duplo-Cego
Proteínas do Ovo/química
Gorduras Insaturadas/química
Feminino
Análise de Alimentos
Seres Humanos
Hipertrigliceridemia/sangue
Hipertrigliceridemia/dietoterapia
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Carbohydrates); 0 (Dietary Carbohydrates); 0 (Dietary Fats); 0 (Dietary Proteins); 0 (Egg Proteins); 0 (Fats, Unsaturated); 0 (Triglycerides)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170519
[St] Status:MEDLINE
[do] DOI:10.3945/jn.117.248641


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[PMID]:28858456
[Au] Autor:Dinicolantonio JJ; Harcombe Z; O'Keefe JH
[Ti] Título:Problems with the 2015 Dietary Guidelines for Americans. An Alternative.
[So] Source:Minn Med;99(6):40-3, 2016 Sep-Oct.
[Is] ISSN:0026-556X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The updated 2015 Dietary Guidelines for Americans, published in January 2016, have stirred much controversy since the advisory report first appeared. Several important changes have been made, with some recommendations having greater scientific evidence for their support than others. The focus of this review is to discuss specific recommendations from the 2015 Dietary Guidelines for Americans that lack sound scientific evidence; these include: 1) Allowing approximately half of all grains to be refined; 2) The continued recommendations for fat-free or low-fat dairy and limitation of saturated fat intake to <10% of calories; 3) Sodium intake < 2,300 mg/day; and 4) Consumption of up to 27 g/day of "oils" (high in polyunsaturated fat or monounsaturated fat). Based on our review, the aforementioned recommendations found in the updated 2015 Dietary Guidelines for Americans may increase the incidence of cardiometabolic disease, diabetes, obesity, dyslipidemia, cardiovascular disease and possibly cancer.
[Mh] Termos MeSH primário: Política Nutricional
[Mh] Termos MeSH secundário: Gorduras na Dieta/administração & dosagem
Grãos Comestíveis
Gorduras Insaturadas/administração & dosagem
Seres Humanos
Necessidades Nutricionais
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Dietary Fats); 0 (Fats, Unsaturated)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171103
[Lr] Data última revisão:
171103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170901
[St] Status:MEDLINE


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[PMID]:27537847
[Au] Autor:Martinez-Hervas S; Navarro I; Real JT; Artero A; Peiro M; Gonzalez-Navarro H; Carmena R; Ascaso JF
[Ad] Endereço:Service of Endocrinology and Nutrition, Hospital Clínico Universitario Valencia, Valencia, Spain.
[Ti] Título:Unsaturated Oral Fat Load Test Improves Glycemia, Insulinemia and Oxidative Stress Status in Nondiabetic Subjects with Abdominal Obesity.
[So] Source:PLoS One;11(8):e0161400, 2016.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:AIMS: To evaluate the changes in glycemia, insulinemia, and oxidative stress markers during an oral fat load test in nondiabetic subjects with abdominal obesity and to analyze the association between postprandial oxidative stress markers and postprandial glucose and insulin responses. METHODS: We included 20 subjects with abdominal obesity (waist circumference > 102 cm for men and > 88 cm for women) and 20 healthy lean controls (waist circumference < 102 cm for men and < 88 cm for women). After 12 hours of fasting we performed a standardized fat load test (0-8 hours) with supracal® (50 g/m2). We determined metabolic parameters, oxidized and reduced glutathione, and malondialdehyde. RESULTS: In both groups, insulin, HOMA, oxidized/reduced glutathione ratio, and malondialdehyde significantly decreased in the postprandial state after the OFLT. All these parameters were significantly higher in the abdominal obesity group at baseline and during all the postprandial points, but the reduction from the baseline levels was significantly higher in the abdominal obesity group. CONCLUSION: Unsaturated fat improves insulin resistance and oxidative stress status. It is possible that a consumption of unsaturated fat could be beneficial even in subjects with abdominal obesity in postprandial state.
[Mh] Termos MeSH primário: Glicemia/efeitos dos fármacos
Gorduras Insaturadas/farmacologia
Insulina/sangue
Estresse Oxidativo/efeitos dos fármacos
Período Pós-Prandial/efeitos dos fármacos
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Estudos de Casos e Controles
Feminino
Glutationa/sangue
Glutationa/metabolismo
Seres Humanos
Resistência à Insulina
Masculino
Malondialdeído/sangue
Malondialdeído/metabolismo
Meia-Idade
Obesidade Abdominal
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Fats, Unsaturated); 0 (Insulin); 4Y8F71G49Q (Malondialdehyde); GAN16C9B8O (Glutathione)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170726
[Lr] Data última revisão:
170726
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160819
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0161400


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[PMID]:27434027
[Au] Autor:Imamura F; Micha R; Wu JH; de Oliveira Otto MC; Otite FO; Abioye AI; Mozaffarian D
[Ad] Endereço:Medical Research Council Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, Cambridge, United Kingdom.
[Ti] Título:Effects of Saturated Fat, Polyunsaturated Fat, Monounsaturated Fat, and Carbohydrate on Glucose-Insulin Homeostasis: A Systematic Review and Meta-analysis of Randomised Controlled Feeding Trials.
[So] Source:PLoS Med;13(7):e1002087, 2016 Jul.
[Is] ISSN:1549-1676
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Effects of major dietary macronutrients on glucose-insulin homeostasis remain controversial and may vary by the clinical measures examined. We aimed to assess how saturated fat (SFA), monounsaturated fat (MUFA), polyunsaturated fat (PUFA), and carbohydrate affect key metrics of glucose-insulin homeostasis. METHODS AND FINDINGS: We systematically searched multiple databases (PubMed, EMBASE, OVID, BIOSIS, Web-of-Knowledge, CAB, CINAHL, Cochrane Library, SIGLE, Faculty1000) for randomised controlled feeding trials published by 26 Nov 2015 that tested effects of macronutrient intake on blood glucose, insulin, HbA1c, insulin sensitivity, and insulin secretion in adults aged ≥18 years. We excluded trials with non-isocaloric comparisons and trials providing dietary advice or supplements rather than meals. Studies were reviewed and data extracted independently in duplicate. Among 6,124 abstracts, 102 trials, including 239 diet arms and 4,220 adults, met eligibility requirements. Using multiple-treatment meta-regression, we estimated dose-response effects of isocaloric replacements between SFA, MUFA, PUFA, and carbohydrate, adjusted for protein, trans fat, and dietary fibre. Replacing 5% energy from carbohydrate with SFA had no significant effect on fasting glucose (+0.02 mmol/L, 95% CI = -0.01, +0.04; n trials = 99), but lowered fasting insulin (-1.1 pmol/L; -1.7, -0.5; n = 90). Replacing carbohydrate with MUFA lowered HbA1c (-0.09%; -0.12, -0.05; n = 23), 2 h post-challenge insulin (-20.3 pmol/L; -32.2, -8.4; n = 11), and homeostasis model assessment for insulin resistance (HOMA-IR) (-2.4%; -4.6, -0.3; n = 30). Replacing carbohydrate with PUFA significantly lowered HbA1c (-0.11%; -0.17, -0.05) and fasting insulin (-1.6 pmol/L; -2.8, -0.4). Replacing SFA with PUFA significantly lowered glucose, HbA1c, C-peptide, and HOMA. Based on gold-standard acute insulin response in ten trials, PUFA significantly improved insulin secretion capacity (+0.5 pmol/L/min; 0.2, 0.8) whether replacing carbohydrate, SFA, or even MUFA. No significant effects of any macronutrient replacements were observed for 2 h post-challenge glucose or insulin sensitivity (minimal-model index). Limitations included a small number of trials for some outcomes and potential issues of blinding, compliance, generalisability, heterogeneity due to unmeasured factors, and publication bias. CONCLUSIONS: This meta-analysis of randomised controlled feeding trials provides evidence that dietary macronutrients have diverse effects on glucose-insulin homeostasis. In comparison to carbohydrate, SFA, or MUFA, most consistent favourable effects were seen with PUFA, which was linked to improved glycaemia, insulin resistance, and insulin secretion capacity.
[Mh] Termos MeSH primário: Glicemia/análise
Carboidratos da Dieta/efeitos adversos
Gorduras Insaturadas/efeitos adversos
Ácidos Graxos Monoinsaturados/efeitos adversos
Ácidos Graxos Insaturados/efeitos adversos
Homeostase
Insulina/sangue
[Mh] Termos MeSH secundário: Adulto
Glicemia/fisiologia
Hemoglobina A Glicada/análise
Seres Humanos
Insulina/fisiologia
Ensaios Clínicos Controlados Aleatórios como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE; META-ANALYSIS; REVIEW
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Dietary Carbohydrates); 0 (Fats, Unsaturated); 0 (Fatty Acids, Monounsaturated); 0 (Fatty Acids, Unsaturated); 0 (Glycated Hemoglobin A); 0 (Insulin); 0 (hemoglobin A1c protein, human)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160720
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pmed.1002087


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[PMID]:27419127
[Au] Autor:Hamid MF; Idroas MY; Ishak MZ; Zainal Alauddin ZA; Miskam MA; Abdullah MK
[Ad] Endereço:School of Mechanical Engineering, Universiti Sains Malaysia, Engineering Campus, Seri Ampangan, 14300 Nibong Tebal, Pulau Pinang, Malaysia.
[Ti] Título:An Experimental Study of Briquetting Process of Torrefied Rubber Seed Kernel and Palm Oil Shell.
[So] Source:Biomed Res Int;2016:1679734, 2016.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Torrefaction process of biomass material is essential in converting them into biofuel with improved calorific value and physical strength. However, the production of torrefied biomass is loose, powdery, and nonuniform. One method of upgrading this material to improve their handling and combustion properties is by densification into briquettes of higher density than the original bulk density of the material. The effects of critical parameters of briquetting process that includes the type of biomass material used for torrefaction and briquetting, densification temperature, and composition of binder for torrefied biomass are studied and characterized. Starch is used as a binder in the study. The results showed that the briquette of torrefied rubber seed kernel (RSK) is better than torrefied palm oil shell (POS) in both calorific value and compressive strength. The best quality of briquettes is yielded from torrefied RSK at the ambient temperature of briquetting process with the composition of 60% water and 5% binder. The maximum compressive load for the briquettes of torrefied RSK is 141 N and the calorific value is 16 MJ/kg. Based on the economic evaluation analysis, the return of investment (ROI) for the mass production of both RSK and POS briquettes is estimated in 2-year period and the annual profit after payback was approximately 107,428.6 USD.
[Mh] Termos MeSH primário: Gorduras Insaturadas/química
Óleos Vegetais/química
[Mh] Termos MeSH secundário: Biocombustíveis
Biomassa
Força Compressiva
Óleo de Palmeira
Temperatura Ambiente
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biofuels); 0 (Fats, Unsaturated); 0 (Plant Oils); 0 (rubber seed oil); 059QF0KO0R (Water); 5QUO05548Z (Palm Oil)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160716
[St] Status:MEDLINE
[do] DOI:10.1155/2016/1679734


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[PMID]:26795690
[Au] Autor:Sánchez DA; Tonetto GM; Ferreira ML
[Ad] Endereço:Planta Piloto de Ingeniería Química (PLAPIQUI), Universidad Nacional del Sur, CONICET, Camino La Carrindanga Km 7, CC 717, 8000 Bahía Blanca, Argentina.
[Ti] Título:An insight on acyl migration in solvent-free ethanolysis of model triglycerides using Novozym 435.
[So] Source:J Biotechnol;220:92-9, 2016 Feb 20.
[Is] ISSN:1873-4863
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:In this work, the ethanolysis of triglycerides catalyzed by immobilized lipase was studied, focusing on the secondary reaction of acyl migration. The catalytic tests were performed in a solvent-free reaction medium using Novozym 435 as biocatalyst. The selected experimental variables were biocatalyst loading (5-20mg), reaction time (30-90min), and chain length of the fatty acids in triglycerides with and without unsaturation (short (triacetin), medium (tricaprylin) and long (tripalmitin/triolein)). The formation of 2-monoglyceride by ethanolysis of triglycerides was favored by long reaction times and large biocatalyst loading with saturated short- to medium-chain triglycerides. In the case of long-chain triglycerides, the formation of this monoglyceride was widely limited by acyl migration. In turn, acyl migration increased the yield of ethyl esters and minimized the content of monoglycerides and diglycerides. Thus, the enzymatic synthesis of biodiesel was favored by long-chain triglycerides (which favor the acyl migration), long reaction times and large biocatalyst loading. The conversion of acylglycerides made from long-chain fatty acids with unsaturation was relatively low due to limitations in their access to the active site of the lipase.
[Mh] Termos MeSH primário: Lipase/química
Lipase/metabolismo
Modelos Químicos
Triglicerídeos/síntese química
[Mh] Termos MeSH secundário: Biocombustíveis
Cromatografia Gasosa/métodos
Diglicerídeos/síntese química
Diglicerídeos/química
Enzimas/química
Enzimas Imobilizadas/química
Ésteres/síntese química
Etil-Éteres/síntese química
Etil-Éteres/química
Gorduras Insaturadas/síntese química
Gorduras Insaturadas/química
Ácidos Graxos/química
Ácidos Graxos/metabolismo
Glicerol/síntese química
Glicerol/química
Cinética
Monoglicerídeos/síntese química
Monoglicerídeos/química
Solventes/química
Triglicerídeos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biofuels); 0 (Diglycerides); 0 (Enzymes); 0 (Enzymes, Immobilized); 0 (Esters); 0 (Ethyl Ethers); 0 (Fats, Unsaturated); 0 (Fatty Acids); 0 (Monoglycerides); 0 (Solvents); 0 (Triglycerides); EC 3.1.1.- (Novozyme 435); EC 3.1.1.3 (Lipase); PDC6A3C0OX (Glycerol)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160123
[St] Status:MEDLINE


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[PMID]:25753506
[Au] Autor:Ruschke S; Kienberger H; Baum T; Kooijman H; Settles M; Haase A; Rychlik M; Rummeny EJ; Karampinos DC
[Ad] Endereço:Department of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany.
[Ti] Título:Diffusion-weighted stimulated echo acquisition mode (DW-STEAM) MR spectroscopy to measure fat unsaturation in regions with low proton-density fat fraction.
[So] Source:Magn Reson Med;75(1):32-41, 2016 Jan.
[Is] ISSN:1522-2594
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To propose and optimize diffusion-weighted stimulated echo acquisition mode (DW-STEAM) for measuring fat unsaturation in the presence of a strong water signal by suppressing the water signal based on a shorter T2 and higher diffusivity of water relative to fat. METHODS: A parameter study for point-resolved spectroscopy (PRESS) and STEAM using oil phantoms was performed and correlated with gas chromatography (GC). Simulations of muscle tissue signal behavior using DW-STEAM and long-echo time (TE) PRESS and a parameter optimization for DW-STEAM were conducted. DW-STEAM and long-TE PRESS were applied in the gastrocnemius muscles of nine healthy subjects. RESULTS: STEAM with TE and mixing time (TM) up to 45 ms exhibited R(2) correlations above 0.98 with GC and little T2 -weighting and J-modulation for the quantified olefinic/methylene peak ratio. The optimal parameters for muscle tissue using DW-STEAM were b-value = 1800 s/mm(2), TE = 33 ms, TM = 30 ms, and repetition time = 2300 ms. In vivo measured mean olefinic signal-to-noise ratios were 72 and 40, mean apparent olefinic water fractions were 0.19 and 0.11 for DW-STEAM and long-TE PRESS, respectively. CONCLUSION: Optimized DW-STEAM MR spectroscopy is superior to long-TE PRESS for measuring fat unsaturation, if a strong water peak prevents the olefinic fat signal's quantification at shorter TEs and water's tissue specific ADC is substantially higher than fat.
[Mh] Termos MeSH primário: Algoritmos
Imagem de Difusão por Ressonância Magnética/métodos
Gorduras Insaturadas/metabolismo
Músculo Esquelético/anatomia & histologia
Músculo Esquelético/metabolismo
Espectroscopia de Prótons por Ressonância Magnética/métodos
[Mh] Termos MeSH secundário: Adulto
Feminino
Seres Humanos
Aumento da Imagem/métodos
Interpretação de Imagem Assistida por Computador/métodos
Masculino
Reprodutibilidade dos Testes
Sensibilidade e Especificidade
Distribuição Tecidual
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Fats, Unsaturated)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150311
[St] Status:MEDLINE
[do] DOI:10.1002/mrm.25578


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[PMID]:26685358
[Ti] Título:Higher blood levels of unsaturated fats linked to longer life.
[So] Source:Harv Heart Lett;26(1):8, 2015 Sep.
[Is] ISSN:1051-5313
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Gorduras Insaturadas na Dieta/sangue
Gorduras Insaturadas
Expectativa de Vida
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Seres Humanos
Meia-Idade
[Pt] Tipo de publicação:NEWS
[Nm] Nome de substância:
0 (Dietary Fats, Unsaturated); 0 (Fats, Unsaturated)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:K
[Da] Data de entrada para processamento:151222
[St] Status:MEDLINE


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[PMID]:26018773
[Au] Autor:Cert R; Madrona A; Espartero JL; Pérez-Camino MC
[Ad] Endereço:Instituto de la Grasa, CSIC, Campus Universidad Pablo de Olavide, E41013 Seville, Spain.
[Ti] Título:Antioxidant activity of alkyl hydroxytyrosyl ethers in unsaturated lipids.
[So] Source:Food Funct;6(6):1999-2007, 2015 Jun.
[Is] ISSN:2042-650X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The antioxidant activity of ethyl and octyl hydroxytyrosyl ethers toward lipids was determined using the Rancimat and open cup methods at high temperatures and 50 °C, respectively. The effect of the unsaturation of the matrix was evaluated using sunflower, soya, and fish refined oils. The antioxidant activities of alkyl hydroxytyrosyl ethers (HTy ethers), hydroxytyrosyl esters, and free hydroxytyrosol are similar, and are much higher than that of α-tocopherol at the same millimolar concentration. The relationship between the induction period and the concentration of the HTy ethers is a sigmoidal curve; an accurate concentration of HTy ethers is necessary to achieve maximum activity, as it increases with the level of matrix unsaturation. The presence of tocopherols in commercial oils affects the antioxidant effect of HTy ethers. Thus, the addition of a low concentration of HTy ethers results in a positive effect, whereas the effect of the addition of high amounts of ethers is slightly less than that of the phenol alone. The addition of HTy ethers to commercial refined oils increases the stability of the oils and preserves tocopherols and polyunsaturated fatty acids from oxidation, enabling the oils to maintain their nutritional properties for longer periods of time.
[Mh] Termos MeSH primário: Antioxidantes/química
Gorduras Insaturadas na Dieta/análise
Gorduras Insaturadas/química
Conservantes de Alimentos/química
Álcool Feniletílico/análogos & derivados
[Mh] Termos MeSH secundário: Alquilação
Éteres/química
Gorduras Insaturadas/análise
Óleos de Peixe/química
Qualidade dos Alimentos
Armazenamento de Alimentos
Temperatura Alta/efeitos adversos
Cinética
Peróxidos Lipídicos/análise
Oxirredução
Álcool Feniletílico/química
Óleos Vegetais/química
Óleo de Soja/química
Óleo de Girassol
Tocoferóis/análise
Tocoferóis/química
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Antioxidants); 0 (Dietary Fats, Unsaturated); 0 (Ethers); 0 (Fats, Unsaturated); 0 (Fish Oils); 0 (Food Preservatives); 0 (Lipid Peroxides); 0 (Plant Oils); 0 (Sunflower Oil); 0 (ethyl hydroxytyrosyl ether); 0 (octyl hydroxytyrosyl ether); 10597-60-1 (3,4-dihydroxyphenylethanol); 8001-22-7 (Soybean Oil); ML9LGA7468 (Phenylethyl Alcohol); R0ZB2556P8 (Tocopherols)
[Em] Mês de entrada:1603
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150529
[St] Status:MEDLINE
[do] DOI:10.1039/c5fo00300h



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