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[PMID]:28752804
[Au] Autor:Khaskheli AA; Talpur FN; Cebeci Aydin A; Jawaid S; Surhio MA; Afridi HI
[Ad] Endereço:a National Center of Excellence in Analytical Chemistry , University of Sindh , Jamshoro , Pakistan.
[Ti] Título:One-pot conjugated linoleic acid production from castor oil by Rhizopus oryzae lipase and resting cells of Lactobacillus plantarum.
[So] Source:Biosci Biotechnol Biochem;81(10):2002-2008, 2017 Oct.
[Is] ISSN:1347-6947
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Conjugated linoleic acid (CLA) has attracted as novel type of fatty acids having unusual health-promoting properties such as anticarcinogenic and antiobesitic effects. The present work employed castor oil as substrate for one-pot production of CLA using washed cells of Lactobacillus plantarum (L. plantarum) and lipases as catalysts. Among the screened lipases, the lipase Rhizopus oryzae (ROL) greatly assisted resting cells to produce CLA. Mass spectral analysis of the product showed that two major isomers of CLA were produced in the reaction mixture i.e. cis-9, trans-11 56.55% and trans-10, cis-12 43.45%. Optimum factors for CLA synthesis were found as substrate concentration (8 mg/mL), pH (6.5), washed cell concentration (12% w/v), and incubation time of 20 h. Hence, the combination of ROL with L. plantarum offers one pot production of CLA selectively using castor oil as a cost-effective substrate.
[Mh] Termos MeSH primário: Biotecnologia/métodos
Óleo de Rícino/metabolismo
Lactobacillus plantarum/citologia
Lactobacillus plantarum/metabolismo
Ácidos Linoleicos Conjugados/biossíntese
Lipase/metabolismo
Rhizopus/enzimologia
[Mh] Termos MeSH secundário: Biotecnologia/economia
Análise Custo-Benefício
Concentração de Íons de Hidrogênio
Hidrólise
Cinética
Ácidos Linoleicos Conjugados/metabolismo
Probióticos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Linoleic Acids, Conjugated); 8001-79-4 (Castor Oil); EC 3.1.1.3 (Lipase)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170729
[St] Status:MEDLINE
[do] DOI:10.1080/09168451.2017.1356218


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[PMID]:28683390
[Au] Autor:Andrade TA; Errico M; Christensen KV
[Ad] Endereço:Department of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark. Electronic address: thal@kbm.sdu.dk.
[Ti] Título:Influence of the reaction conditions on the enzyme catalyzed transesterification of castor oil: A possible step in biodiesel production.
[So] Source:Bioresour Technol;243:366-374, 2017 Nov.
[Is] ISSN:1873-2976
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The identification of the influence of the reaction parameters is of paramount importance when defining a process design. In this work, non-edible castor oil was reacted with methanol to produce a possible component for biodiesel blends, using liquid enzymes as the catalyst. Temperature, alcohol-to-oil molar ratio, enzyme and added water contents were the reaction parameters evaluated in the transesterification reactions. The optimal conditions, giving the optimal final FAME yield and FFA content in the methyl ester-phase was identified. At 35°C, 6.0 methanol-to-oil molar ratio, 5wt% of enzyme and 5wt% of water contents, 94% of FAME yield and 6.1% of FFA in the final composition were obtained. The investigation was completed with the analysis of the component profiles, showing that at least 8h are necessary to reach a satisfactory FAME yield together with a minor FFA content.
[Mh] Termos MeSH primário: Biocombustíveis
Óleo de Rícino
[Mh] Termos MeSH secundário: Catálise
Esterificação
Metanol
Óleos Vegetais
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biofuels); 0 (Plant Oils); 8001-79-4 (Castor Oil); Y4S76JWI15 (Methanol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171023
[Lr] Data última revisão:
171023
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE


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[PMID]:28640614
[Au] Autor:da Cruz DF; Bortoletto-Santos R; Guimarães GGF; Polito WL; Ribeiro C
[Ad] Endereço:Instituto de Química de São Carlos (IQSC), Universidade de São Paulo (USP) , Campus de São Carlos, Avenida Trabalhador São-Carlense 400, Caixa Postal 780, Arnold Schimidt, São Carlos, São Paulo 13566-590, Brazil.
[Ti] Título:Role of Polymeric Coating on the Phosphate Availability as a Fertilizer: Insight from Phosphate Release by Castor Polyurethane Coatings.
[So] Source:J Agric Food Chem;65(29):5890-5895, 2017 Jul 26.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The coating of fertilizers with polymers is an acknowledged strategy for controlling the release of nutrients and their availability in soil. However, its effectiveness in the case of soluble phosphate fertilizers is still uncertain, and information is lacking concerning the chemical properties and structures of such coatings. Here, an oil-based hydrophobic polymer system (polyurethane) is proposed for the control of the release of phosphorus from diammonium phosphate (DAP) granules. This material was systematically characterized, with evaluation of the delivery mechanism and the availability of phosphate in an acid soil. The results indicated that thicker coatings can change the maximum nutrient availability toward longer periods, such as 4.5-7.5 wt % DAP coated, that presented the highest concentrations at 336 h, as compared to 168 h for uncoated DAP. In contrast, DAP treated with 9.0 wt % began to increase the concentration after 168 h until it results in maximum release at 672 h. These effects could be attributed to the homogeneity of the polymer and the porosity. The strategy successfully provided long-term availability of a phosphate source.
[Mh] Termos MeSH primário: Fertilizantes/análise
Fosfatos/química
Poliuretanos/química
[Mh] Termos MeSH secundário: Óleo de Rícino/química
Cinética
Porosidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fertilizers); 0 (Phosphates); 0 (Polyurethanes); 8001-79-4 (Castor Oil)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170809
[Lr] Data última revisão:
170809
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170623
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b01686


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[PMID]:28626135
[Au] Autor:Enomoto Y; Imai Y; Tajima K
[Ad] Endereço:Graduate School of Applied Chemistry, Kanagawa University.
[Ti] Título:Adsorption of the Three-phase Emulsion on Various Solid Surfaces.
[So] Source:J Oleo Sci;66(7):689-697, 2017 Jul 01.
[Is] ISSN:1347-3352
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The present study investigates the adsorption of the three-phase emulsion on various solid/water interfaces. Vesicles can be used as emulsifiers in the three-phase emulsions and act as an independent phase unlike the surfactant used in conventional emulsions; therefore, it is expected that the three-phase emulsion formed by the adhesion of vesicles to the oil/water interface will adsorb on various solid/water interfaces. The cationic three-phase emulsion was prepared to encourage emulsion adsorption on negatively charged solid substrates in water. The emulsifier polyoxyethylene-(10) hydrogenated castor oil was rendered cationic by mixing with the surfactant cetyltrimethylammonium bromide and then used to prepare the cationic three-phase emulsion of hexadecane-in-water. Three solid substrates (silicon, glass, and copper) were dipped in the cationic emulsion and the emulsion was found to adsorb on the solid substrates while maintaining its structure. The amount of hexadecane adsorbed on the various surfaces was investigated by gas chromatography and found to increase with increasing hexadecane concentration in the emulsion and eventually plateaued just like molecular adsorption. The maximum surface coverage of the emulsion on the substrates was approximately 80%. However, even the equivalent nonionic three-phase emulsion was found to adsorb on the three solid surfaces. This was attributed to a novel mechanism of irreversible adhesion via the van der Waals attractive force.
[Mh] Termos MeSH primário: Emulsões/química
[Mh] Termos MeSH secundário: Adsorção
Alcanos/química
Óleo de Rícino/análogos & derivados
Óleo de Rícino/química
Compostos de Cetrimônio/química
Cromatografia Gasosa
Cobre
Vidro
Silicones
Propriedades de Superfície
Tensoativos/química
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkanes); 0 (Cetrimonium Compounds); 0 (Emulsions); 0 (Silicones); 0 (Surface-Active Agents); 059QF0KO0R (Water); 61791-12-6 (polyethoxylated castor oil); 789U1901C5 (Copper); 8001-79-4 (Castor Oil); F8Z00SHP6Q (n-hexadecane); Z7FF1XKL7A (cetrimonium)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess16246


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[PMID]:28626133
[Au] Autor:Yu X; Wang N; Zhang R; Zhao Z
[Ad] Endereço:College of Food Science and Engineering, Northwest A&F University.
[Ti] Título:Simple Synthesis Hydrogenated Castor Oil Fatty Amide Wax and Its Coating Characterization.
[So] Source:J Oleo Sci;66(7):659-665, 2017 Jul 01.
[Is] ISSN:1347-3352
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:A simple method for incorporating amine groups in hydrogenated castor oil (HCO) to produce wax for beeswax or carnauba wax substitution in packaging and coating was developed. From the conversion rate of the products, HCO was reacted with ethanolamine at 150°C for 5 h, and the molar ratio of HCO and ethanolamine was 1:4. The hardness of the final product was seven times higher than that of beeswax, the cohesiveness of the final product was 1.3 times higher than that of beeswax and approximately one half of that of carnauba wax, and the melting point of the final product is 98°C. The Fourier transform Infrared spectroscopy showed that the amide groups were incorporated to form the amide products. In coating application, the results showed that the force of the final product coating cardboard was higher than that of beeswax and paraffin wax and less than that of carnauba wax. After 24 h soaking, the compression forces were decreased. HCO fatty acid wax can be an alternative wax for carnauba wax and beeswax in coating applications.
[Mh] Termos MeSH primário: Amidas/síntese química
Óleo de Rícino/análogos & derivados
Fenômenos Químicos
Técnicas de Química Sintética/métodos
Etanolamina/química
Ceras/síntese química
[Mh] Termos MeSH secundário: Óleo de Rícino/química
Temperatura Alta
Hidrogenação
Espectroscopia de Infravermelho com Transformada de Fourier
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amides); 0 (Waxes); 5KV86114PT (Ethanolamine); 61791-12-6 (polyethoxylated castor oil); 8001-79-4 (Castor Oil)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess16213


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[PMID]:28300879
[Au] Autor:Santos VT; Facco GG; Ortiz HC; Silva IS
[Ad] Endereço:Postgraduate Program in Health and Development, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil.
[Ti] Título:Behavior study of the doped castor bean polymer rod with bioactive glass and hidroxyapatite in mice femur medullary canal.
[So] Source:Acta Cir Bras;32(2):116-124, 2017 Feb.
[Is] ISSN:1678-2674
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Purpose To evaluate the polymer doped rods behavior with bioactive glass and hydroxyapatite for possible application as a fracture fixing method. Methods Twenty eight Rattus norvegicus Wistar underwent bone defect for access to the femoral medullary canal and distributed into three experimental groups: group A - doped castor bean polymer with bioactive glass; group B - castor bean polymer and; group C - castor bean polymer doped with bioactive glass and hydroxyapatite. After 15 and 60 evaluation days, the femurs were removed and sent for histology and scanning electron microscopy. Results Initially mild and moderate inflammatory infiltrate is observed that decreases as time goes by, and the presence of connective tissue capsule around the graft in all groups. Regarding the biomaterials resorption little was observed. The implanted rods did not favor the osteoconductive process in the femoral medullary canal which was observed only in the C15 group. Conclusions The association of castor bean polymer, bioactive glass and hydroxyapatite was biocompatible and osteointegrable. The osteoconductive only occurred in the presence of hydroxyapatite and bioactive glass (C15 Group) and little biodegradation was observed.
[Mh] Termos MeSH primário: Materiais Biocompatíveis/uso terapêutico
Regeneração Óssea
Óleo de Rícino/química
Durapatita/uso terapêutico
Fêmur
Fixação Interna de Fraturas/métodos
Vidro/química
[Mh] Termos MeSH secundário: Animais
Materiais Biocompatíveis/química
Durapatita/química
Fixadores Internos
Modelos Animais
Distribuição Aleatória
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biocompatible Materials); 8001-79-4 (Castor Oil); 91D9GV0Z28 (Durapatite)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170830
[Lr] Data última revisão:
170830
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170317
[St] Status:MEDLINE


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[PMID]:28282989
[Au] Autor:Lu M; Xiong D; Sun W; Yu T; Hu Z; Ding J; Cai Y; Yang S; Pan B
[Ad] Endereço:a The Department of Veterinary Parasitology, College of Veterinary Medicine, China Agriculture University , Hai Dian District , Beijing , China.
[Ti] Título:Sustained release ivermectin-loaded solid lipid dispersion for subcutaneous delivery: in vitro and in vivo evaluation.
[So] Source:Drug Deliv;24(1):622-631, 2017 Nov.
[Is] ISSN:1521-0464
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This work aimed to develop a sustained release solid dispersion of ivermectin (IVM-SD) in a lipid matrix (hydrogenated castor oil, HCO) for subcutaneous delivery. Solvent-melting technology was employed to prepare IVM-SDs using HCO. The physicochemical properties of the IVM-SDs were evaluated by scanning electron microscopy (SEM), X-ray powder diffraction (XRPD), and Fourier transform infrared spectroscopy (FTIR). The release of IVM from IVM-SDs was evaluated with HPLC in vitro. Pharmacokinetics of IVM was studied in rabbits following a single subcutaneous administration of IVM-SD formulations. The efficacy of IVM-SD against the ear mange mite was evaluated in rabbits. IVM was completely dispersed in HCO in an amorphous state at a drug:carrier ratio lower than 1:3. No chemical interactions between drug and carrier were found besides hydrogen bonding for the amorphous IVM-SDs. The amorphous IVM-SDs formulations exhibited a sustained release of IVM versus physical mixtures (PMs) of IVM and HCO. The drug release decreased as the drug:carrier ratios decreased, and the release kinetics of IVM were controlled via diffusion. Cytotoxicity of IVM-SD to MDCK cells was lower than native IVM. The IVM plasma concentration of SD1:3 remained above 1 ng/mL for 49 d. Higher AUC, MRT, and T values were obtained at a SD1:3 relative to the IVM group. The IVM-SD improved almost 1.1-fold bioavailability of drug compared with IVM in rabbits. IVM-SD could provide longer persistence against rabbit's ear mites than a commercial IVM injection. This study shows that these solid lipid dispersions are a promising approach for the development of subcutaneous IVM formulations.
[Mh] Termos MeSH primário: Antiparasitários/administração & dosagem
Óleo de Rícino/química
Portadores de Fármacos
Ivermectina/administração & dosagem
Infestações por Ácaros/veterinária
Psoroptidae/efeitos dos fármacos
[Mh] Termos MeSH secundário: Animais
Antiparasitários/química
Antiparasitários/farmacocinética
Antiparasitários/toxicidade
Disponibilidade Biológica
Óleo de Rícino/análogos & derivados
Óleo de Rícino/toxicidade
Sobrevivência Celular/efeitos dos fármacos
Cromatografia Líquida de Alta Pressão
Cristalografia por Raios X
Preparações de Ação Retardada
Cães
Composição de Medicamentos
Hidrogenação
Injeções Subcutâneas
Ivermectina/química
Ivermectina/farmacocinética
Ivermectina/toxicidade
Células Madin Darby de Rim Canino
Masculino
Microscopia Eletrônica de Varredura
Infestações por Ácaros/tratamento farmacológico
Infestações por Ácaros/parasitologia
Difração de Pó
Coelhos
Solubilidade
Espectroscopia de Infravermelho com Transformada de Fourier
Tecnologia Farmacêutica/métodos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antiparasitic Agents); 0 (Delayed-Action Preparations); 0 (Drug Carriers); 70288-86-7 (Ivermectin); 8001-79-4 (Castor Oil)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170321
[Lr] Data última revisão:
170321
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170312
[St] Status:MEDLINE
[do] DOI:10.1080/10717544.2017.1284945


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[PMID]:28183311
[Au] Autor:Sisay M; Engidawork E; Shibeshi W
[Ad] Endereço:School of Pharmacy, College of Health and Medical sciences, Haramaya University, Dire Dawa, Ethiopia.
[Ti] Título:Evaluation of the antidiarrheal activity of the leaf extracts of Myrtus communis Linn (Myrtaceae) in mice model.
[So] Source:BMC Complement Altern Med;17(1):103, 2017 Feb 10.
[Is] ISSN:1472-6882
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Myrtus communis L. has a folkloric repute for the management of diarrhea and dysentery in different parts of the world. However, the safety and efficacy of the leaf extract have not been scientifically validated in animal model. This study was, therefore, aimed to investigate the antidiarrheal effect of 80% methanol extract (80ME) and solvent fractions of the leaves of Myrtus communis L. in mice. METHODS: The antidiarrheal activity of the 80ME and solvent fractions was evaluated against castor oil induced diarrheal model, charcoal meal and enteropooling tests. For the 80%ME, the test groups received 100, 200 and 400 mg/kg of the extract. In case of fractions, the test groups received various doses of fractions (200, 300, 400 mg/kg and an additional dose of 800 mg/kg for the aqueous fraction (AF)), where as negative controls received the vehicle (10 ml/kg) and positive controls received loperamide (3 mg/kg). RESULTS: The 80ME at 200 mg/kg (p < 0.05) & 400 mg/kg (p < 0.01) as well as the chloroform fraction (CF) and methanol fraction (MF) at 400 mg/kg (p < 0.05) significantly delayed the onset of diarrhea. Besides, the 80ME (at all tested doses) and both of these fractions (at 300 & 400 mg/kg) significantly decreased the frequency and weight of fecal outputs. Results from the charcoal meal test revealed that the 80ME, at all doses, (p < 0.001) as well as the CF and MF at 300 mg/kg (p < 0.05) & 400 mg/kg (p < 0.001) produced a significant anti-motility effect. Similarly, in the entero-pooling test, the 80ME (at all tested doses) (p < 0.01) as well as the CF and MF (at 300 & 400 mg/kg, p < 0.05) produced a significant decline in the weight and volume of intestinal contents, whereas the AF revealed significant effect (p < 0.05) at dose of 800 mg/kg only. CONCLUSION: The study demonstrated that the 80ME and solvent fractions contain bioactive constituents that have antidiarrheal activity. Therefore, this study provides a scientific support for the acclaimed traditional use of Myrtus communis L for the treatment of diarrheal diseases.
[Mh] Termos MeSH primário: Antidiarreicos/uso terapêutico
Diarreia/tratamento farmacológico
Myrtus/química
Extratos Vegetais/uso terapêutico
Folhas de Planta/química
[Mh] Termos MeSH secundário: Animais
Antidiarreicos/química
Antidiarreicos/farmacologia
Óleo de Rícino/efeitos adversos
Diarreia/induzido quimicamente
Modelos Animais de Doenças
Feminino
Metanol
Camundongos
Extratos Vegetais/química
Extratos Vegetais/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antidiarrheals); 0 (Plant Extracts); 8001-79-4 (Castor Oil); Y4S76JWI15 (Methanol)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170211
[St] Status:MEDLINE
[do] DOI:10.1186/s12906-017-1625-3


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[PMID]:28064049
[Au] Autor:Leódido AC; Costa LE; Araújo TS; Costa DS; Sousa NA; Souza LK; Sousa FB; Filho MD; Vasconcelos DF; Silva FR; Nogueira KM; Araújo AR; Barros FC; Freitas AL; Medeiros JV
[Ad] Endereço:The Northeast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, PI 64049-550, Brazil.
[Ti] Título:Anti-diarrhoeal therapeutic potential and safety assessment of sulphated polysaccharide fraction from Gracilaria intermedia seaweed in mice.
[So] Source:Int J Biol Macromol;97:34-45, 2017 Apr.
[Is] ISSN:1879-0003
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Sulphated polysaccharides extracted from algae have been extensively studied for their diverse biological activities. Thus, the purpose of this study was to evaluate the chemical composition, the anti-diarrhoeal effect and acute toxicity of a sulphated polysaccharide fraction obtained from Gracilaria intermedia (SP-Gi). Initially, the FT-IR of SP-Gi revealed to be an agaran with sulphation at C-6 of the l-galactosyl residues. The anti-diarrhoeal activity of SP-Gi was evaluated in a castor oil-induced diarrhoea model. The effects of SP-Gi on enteropooling, Na -K -ATPase activity, gastrointestinal transit, and gastric emptying were then examined. Subsequently, the effect of SP-Gi on diarrhoea induced by cholera toxin (CT) and Escherichia coli was examined. In addition, an acute toxicity test was conducted in accordance with OECD guideline 423. Pre-treatment with SP-Gi reduces the total faeces, total diarrhoeal faeces, and enteropooling. SP-Gi (30mg/kg p.o.) increased Na /K -ATPase activity and reduced gastrointestinal transit through anticholinergic mechanisms. ELISA demonstrated that SP-Gi can interact with GM1 receptors and CT. SP-Gi reduced diarrhoea induced by E. coli and prevented weight loss in the animals. Moreover, SP-Gi did not induce any toxicity signs. These results suggest that SP-Gi is a possible candidate for the treatment of diarrhoeal illnesses.
[Mh] Termos MeSH primário: Diarreia/tratamento farmacológico
Gracilaria/química
Polissacarídeos/efeitos adversos
Polissacarídeos/farmacologia
Segurança
Sulfatos/química
[Mh] Termos MeSH secundário: Animais
Óleo de Rícino/farmacologia
Diarreia/induzido quimicamente
Diarreia/fisiopatologia
Escherichia coli/efeitos dos fármacos
Feminino
Esvaziamento Gástrico/efeitos dos fármacos
Intestinos/efeitos dos fármacos
Intestinos/fisiopatologia
Masculino
Camundongos
Polissacarídeos/química
Polissacarídeos/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Polysaccharides); 0 (Sulfates); 8001-79-4 (Castor Oil)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170410
[Lr] Data última revisão:
170410
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170109
[St] Status:MEDLINE


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[PMID]:28033095
[Au] Autor:Sanaei-Zadeh H; Marashi SM
[Ti] Título:Gastric decontamination in aluminium phosphide poisoning: a case against the use of water-based solutions.
[So] Source:Arh Hig Rada Toksikol;67(4):364-365, 2016 Dec 01.
[Is] ISSN:1848-6312
[Cp] País de publicação:Croatia
[La] Idioma:eng
[Mh] Termos MeSH primário: Compostos de Alumínio/envenenamento
Óleo de Rícino/uso terapêutico
Descontaminação/métodos
Praguicidas/envenenamento
Fosfinas/envenenamento
Óleos Vegetais/uso terapêutico
Envenenamento/terapia
[Mh] Termos MeSH secundário: Lavagem Gástrica
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Aluminum Compounds); 0 (Pesticides); 0 (Phosphines); 0 (Plant Oils); 8001-79-4 (Castor Oil)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161230
[St] Status:MEDLINE



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