Base de dados : MEDLINE
Pesquisa : D10.570.755.375.760.400.800.806 [Categoria DeCS]
Referências encontradas : 761 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 77 ir para página                         

  1 / 761 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28461265
[Au] Autor:Nkanga CI; Krause RW; Noundou XS; Walker RB
[Ad] Endereço:Department of Chemistry, Faculty of Science, Rhodes University, P.O. Box 94, Grahamstown 6140, Eastern Cape, South Africa.
[Ti] Título:Preparation and characterization of isoniazid-loaded crude soybean lecithin liposomes.
[So] Source:Int J Pharm;526(1-2):466-473, 2017 Jun 30.
[Is] ISSN:1873-3476
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Tuberculosis (TB) is a poverty related infectious disease that is rapidly giving rise to public health concerns. Lengthy drug administration and frequent adverse side-effects associated with TB treatment make anti-tubercular drugs (ATDs) good candidates for drug delivery studies. This work aimed to formulate and prepare liposomes as a cost-effective option for ATD delivery. Liposomes were prepared by film hydration using crude soybean lecithin (CL) and not pure phospholipids as in the normal practice. Cholesterol was also used (up to 25% mass ratio), and isoniazid (INH) was encapsulated as model drug using a freeze-thaw loading technique. Purified soybean lecithin (PL) was also used for comparative purposes, under the same conditions. INH-loaded liposomes were characterized for particle size, Zeta Potential (ZP), encapsulation efficiency (EE) and drug release. Physicochemical properties were investigated using thermogravimetric analysis, differential scanning calorimetry, X-ray diffraction and Fourier transform infrared. INH-loaded CL-based liposomes showed high EE (79±2.45%). The average particle size (813.00±9.21nm) and ZP (-42.80±4.31mV) of this formulation are promising for the treatment of TB by pulmonary delivery. These findings suggest the possibility of encapsulating ATDs in liposomes made of crude soybean lecithin that is cheap and readily available.
[Mh] Termos MeSH primário: Isoniazida/química
Lecitinas/química
Lipossomos/química
Feijão de Soja/química
[Mh] Termos MeSH secundário: Química Farmacêutica
Liberação Controlada de Fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lecithins); 0 (Liposomes); V83O1VOZ8L (Isoniazid)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180108
[Lr] Data última revisão:
180108
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170503
[St] Status:MEDLINE


  2 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28796777
[Au] Autor:Mouzouvi CRA; Umerska A; Bigot AK; Saulnier P
[Ad] Endereço:'Micro et Nanomédecines biomimétiques-MINT', INSERM U1066 Université d'Angers, CNRS 6021, Université Bretagne Loire, Angers, France.
[Ti] Título:Surface active properties of lipid nanocapsules.
[So] Source:PLoS One;12(8):e0179211, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Lipid nanocapsules (LNCs) are biomimetic nanocarriers used for the encapsulation of a broad variety of active ingredients. Similar to surface active compounds, LNCs contain both hydrophilic and hydrophobic parts in their structure. Moreover, the components of LNCs, macrogol 15 hydroxystearate (MHS) and lecithin, are known for their surface active properties. Therefore, the aim of this paper was to investigate the capability of the LNCs to decrease surface tension using two techniques: drop tensiometry and the Wilhelmy plate method. LNCs with diameters ranging from 30 to 100 nm were successfully obtained using a phase inversion technique. The LNCs' properties, such as size and zeta potential, depend on the composition. LNCs exhibit a lower limiting surface tension compared to MHS (34.8-35.0 mN/m and 37.7-38.8 mN/m, respectively), as confirmed by both drop tensiometry and the Wilhelmy plate method. LNCs have exhibited a saturated interfacial concentration (SIC) that was 10-fold higher than the critical micellar concentration (CMC) of MHS or the SIC of binary and ternary mixtures of LNC ingredients. The SIC of the LNC formulations depended on the mass mixing ratio of the MHS/triglycerides but not on the presence of lecithin. The CMC/SIC values measured by the Wilhelmy plate method were higher than those obtained using drop tensiometry because of the longer duration of the tensiometry measurement. In conclusion, the surfactant-like properties of the LNCs offer new possibilities for medical and pharmaceutical applications.
[Mh] Termos MeSH primário: Lipídeos/química
Nanocápsulas/química
[Mh] Termos MeSH secundário: Lecitinas/química
Micelas
Polietilenoglicóis/química
Feijão de Soja/química
Estearatos/química
Propriedades de Superfície
Tensão Superficial
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lecithins); 0 (Lipids); 0 (Micelles); 0 (Nanocapsules); 0 (Stearates); 30IQX730WE (Polyethylene Glycols)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171006
[Lr] Data última revisão:
171006
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170811
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0179211


  3 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28765708
[Au] Autor:Hong J; Sun Z; Li Y; Guo Y; Liao Y; Liu M; Wang X
[Ad] Endereço:Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing.
[Ti] Título:Folate-modified Annonaceous acetogenins nanosuspensions and their improved antitumor efficacy.
[So] Source:Int J Nanomedicine;12:5053-5067, 2017.
[Is] ISSN:1178-2013
[Cp] País de publicação:New Zealand
[La] Idioma:eng
[Ab] Resumo:Annonaceous acetogenins (ACGs) are a large family of fatty acid derived natural products that are exclusively isolated from the species. Many members of this diverse family have a broad spectrum of biological activities, the most impressive of which is anticancer activity. However, their poor solubility and severe toxicity restrict their clinical application, and their complicated composition hinders their formulation and drug delivery. In this study, ß-cyclodextrin was modified with folic acid (FA) and then combined with soybean lecithin to prepare FA-modified ACGs nanosuspensions (FA-ACGs-NSps). The obtained FA-ACGs-NSps had a high drug payload of 57.59% and average particle size of 199.5 nm, and they exhibited sustained drug release within 142 hours. In comparison with ACGs-NSps, FA-ACGs-NSps showed significantly enhanced cytotoxicity and higher cell uptake toward folate receptor-positive 4T1 cell lines. An in vivo study demonstrated that FA-ACGs-NSps more effectively accumulated in tumors and enhanced the antitumor therapeutic efficacy with less toxicity in 4T1 tumor bearing mice. Therefore, FA-ACGs-NSps may be a promising drug delivery system for ACGs to improve their therapeutic window and may be suitable for clinical application to treat folate-positive tumors.
[Mh] Termos MeSH primário: Acetogeninas/química
Acetogeninas/farmacologia
Antineoplásicos Fitogênicos/farmacologia
Sistemas de Liberação de Medicamentos/métodos
Ácido Fólico/química
[Mh] Termos MeSH secundário: Acetogeninas/farmacocinética
Animais
Annonaceae/química
Antineoplásicos Fitogênicos/química
Antineoplásicos Fitogênicos/farmacocinética
Peso Corporal/efeitos dos fármacos
Linhagem Celular Tumoral
Feminino
Ácido Fólico/farmacologia
Seres Humanos
Lecitinas/química
Camundongos Endogâmicos BALB C
Nanoestruturas/química
Tamanho da Partícula
Solubilidade
Suspensões/química
Suspensões/farmacologia
Distribuição Tecidual
Ensaios Antitumorais Modelo de Xenoenxerto
beta-Ciclodextrinas/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Acetogenins); 0 (Antineoplastic Agents, Phytogenic); 0 (Lecithins); 0 (Suspensions); 0 (beta-Cyclodextrins); 935E97BOY8 (Folic Acid)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE
[do] DOI:10.2147/IJN.S134284


  4 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28763965
[Au] Autor:Dai L; Sun C; Li R; Mao L; Liu F; Gao Y
[Ad] Endereço:Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food from Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
[Ti] Título:Structural characterization, formation mechanism and stability of curcumin in zein-lecithin composite nanoparticles fabricated by antisolvent co-precipitation.
[So] Source:Food Chem;237:1163-1171, 2017 Dec 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Curcumin (Cur) exhibits a range of bioactive properties, but its application is restrained due to its poor water solubility and sensitivity to environmental stresses. In this study, zein-lecithin composite nanoparticles were fabricated by antisolvent co-precipitation technique for delivery of Cur. The result showed that the encapsulation efficiency of Cur was significantly enhanced from 42.03% in zein nanoparticles to 99.83% in zein-lecithin composite nanoparticles. The Cur entrapped in the nanoparticles was in an amorphous state confirmed by differential scanning calorimetry and X-ray diffraction. Fourier transform infrared analysis revealed that hydrogen bonding, electrostatic interaction and hydrophobic attraction were the main interactions among zein, lecithin, and Cur. Compared with single zein and lecithin nanoparticles, zein-lecithin composite nanoparticles significantly improved the stability of Cur against thermal treatment, UV irradiation and high ionic strength. Therefore, zein-lecithin composite nanoparticles could be a potential delivery system for water-insoluble bioactive compounds with enhanced encapsulation efficiency and chemical stability.
[Mh] Termos MeSH primário: Nanopartículas
[Mh] Termos MeSH secundário: Curcumina
Lecitinas
Tamanho da Partícula
Zeína
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lecithins); 9010-66-6 (Zein); IT942ZTH98 (Curcumin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171030
[Lr] Data última revisão:
171030
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170803
[St] Status:MEDLINE


  5 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28534401
[Au] Autor:Liang L; Chen F; Wang X; Jin Q; Decker EA; McClements DJ
[Ad] Endereço:State Key Laboratory of Food Science and Technology, Synergetic Innovation Center of Food Safety and Nutrition, School of Food Science and Technology, Jiangnan University , Wuxi, Jiangsu 214122 China.
[Ti] Título:Physical and Oxidative Stability of Flaxseed Oil-in-Water Emulsions Fabricated from Sunflower Lecithins: Impact of Blending Lecithins with Different Phospholipid Profiles.
[So] Source:J Agric Food Chem;65(23):4755-4765, 2017 Jun 14.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:There is great interest in the formulation of plant-based foods enriched with nutrients that promote health, such as polyunsaturated fatty acids. This study evaluated the impact of sunflower phospholipid type on the formation and stability of flaxseed oil-in-water emulsions. Two sunflower lecithins (Sunlipon 50 and 90) with different phosphatidylcholine (PC) levels (59 and 90%, respectively) were used in varying ratios to form emulsions. Emulsion droplet size, charge, appearance, microstructure, and oxidation were measured during storage at 55 °C in the dark. The physical and chemical stability increased as the PC content of the lecithin blends decreased. The oxidative stability of emulsions formulated using Sunlipon 50 was better than emulsions formulated using synthetic surfactants (SDS or Tween 20). The results are interpreted in terms of the impact of emulsifier type on the colloidal interactions between oil droplets and on the molecular interactions between pro-oxidants and oil droplet surfaces.
[Mh] Termos MeSH primário: Emulsões/química
Lecitinas/química
Óleo de Semente do Linho/química
Fosfolipídeos/química
Óleos Vegetais/química
[Mh] Termos MeSH secundário: Oxirredução
Tamanho da Partícula
Óleo de Girassol
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Emulsions); 0 (Lecithins); 0 (Phospholipids); 0 (Plant Oils); 0 (Sunflower Oil); 059QF0KO0R (Water); 8001-26-1 (Linseed Oil)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170524
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b01469


  6 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28407907
[Au] Autor:Jatoi MA; Juric S; Vidrih R; Vincekovic M; Vukovic M; Jemric T
[Ad] Endereço:Department of Pomology, Faculty of Agriculture, University of Zagreb, Zagreb 10000, Croatia; Date Palm Research Institute, Shah Abdul Latif University, Khairpur 66020, Sindh, Pakistan. Electronic address: mushtaqjatoi@gmail.com.
[Ti] Título:The effects of postharvest application of lecithin to improve storage potential and quality of fresh goji (Lycium barbarum L.) berries.
[So] Source:Food Chem;230:241-249, 2017 Sep 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:To enhance storage life and post-storage quality of fresh goji berries, three treatments with lecithin (1, 5, 10g·L ) and two storage times (8, 16days) were evaluated. The significant effects on the physiological and biochemical parameters were varied. 1g·L lecithin showed its main effects after 8days of storage by reduction in total weight loss and decay, SSC/TA ratio (also at 16days), and chlorophyll content and with highest scores of sensory attributes (also at 16days). 5g·L lecithin showed its main effects after 16days of storage: highest SSC, highest TA (also at 8days), highest TPC, only significant reduction in DPPH antioxidant activity, and highest total flavonoid content. 10g·L lecithin showed its main effects after 8days of storage with highest SSC, chlorophyll content, total flavonoid, DPPH, and ABTS antioxidant activity (also at 16days), but with least scores of sensory attributes.
[Mh] Termos MeSH primário: Antioxidantes/química
Frutas/química
Lecitinas/química
Lycium/química
[Mh] Termos MeSH secundário: Antioxidantes/análise
Armazenamento de Alimentos
Lecitinas/análise
Oxirredução
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Lecithins)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170628
[Lr] Data última revisão:
170628
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170415
[St] Status:MEDLINE


  7 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28350989
[Au] Autor:Wang H; Moyano AL; Ma Z; Deng Y; Lin Y; Zhao C; Zhang L; Jiang M; He X; Ma Z; Lu F; Xin M; Zhou W; Yoon SO; Bongarzone ER; Lu QR
[Ad] Endereço:Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
[Ti] Título:miR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS.
[So] Source:Dev Cell;40(6):566-582.e5, 2017 Mar 27.
[Is] ISSN:1878-1551
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A lack of sufficient oligodendrocyte myelination contributes to remyelination failure in demyelinating disorders. miRNAs have been implicated in oligodendrogenesis; however, their functions in myelin regeneration remained elusive. Through developmentally regulated targeted mutagenesis, we demonstrate that miR-219 alleles are critical for CNS myelination and remyelination after injury. Further deletion of miR-338 exacerbates the miR-219 mutant hypomyelination phenotype. Conversely, miR-219 overexpression promotes precocious oligodendrocyte maturation and regeneration processes in transgenic mice. Integrated transcriptome profiling and biotin-affinity miRNA pull-down approaches reveal stage-specific miR-219 targets in oligodendrocytes and further uncover a novel network for miR-219 targeting of differentiation inhibitors including Lingo1 and Etv5. Inhibition of Lingo1 and Etv5 partially rescues differentiation defects of miR-219-deficient oligodendrocyte precursors. Furthermore, miR-219 mimics enhance myelin restoration following lysolecithin-induced demyelination as well as experimental autoimmune encephalomyelitis, principal animal models of multiple sclerosis. Together, our findings identify context-specific miRNA-regulated checkpoints that control myelinogenesis and a therapeutic role for miR-219 in CNS myelin repair.
[Mh] Termos MeSH primário: Sistema Nervoso Central/metabolismo
Sistema Nervoso Central/patologia
MicroRNAs/metabolismo
Bainha de Mielina/metabolismo
Bainha de Mielina/patologia
Regeneração Nervosa
Cicatrização
[Mh] Termos MeSH secundário: Animais
Diferenciação Celular/efeitos dos fármacos
Linhagem da Célula/efeitos dos fármacos
Sistema Nervoso Central/efeitos dos fármacos
Doenças Desmielinizantes/genética
Doenças Desmielinizantes/patologia
Modelos Animais de Doenças
Progressão da Doença
Encefalomielite Autoimune Experimental/genética
Encefalomielite Autoimune Experimental/patologia
Deleção de Genes
Lecitinas/farmacologia
Proteínas de Membrana/metabolismo
Camundongos Endogâmicos C57BL
Camundongos Knockout
MicroRNAs/genética
Esclerose Múltipla/genética
Esclerose Múltipla/patologia
Esclerose Múltipla/terapia
Bainha de Mielina/efeitos dos fármacos
Regeneração Nervosa/efeitos dos fármacos
Regeneração Nervosa/genética
Proteínas do Tecido Nervoso/metabolismo
Oligodendroglia/efeitos dos fármacos
Oligodendroglia/metabolismo
Nervo Óptico/patologia
Nervo Óptico/ultraestrutura
Fenótipo
Medula Espinal/efeitos dos fármacos
Medula Espinal/metabolismo
Medula Espinal/patologia
Cicatrização/efeitos dos fármacos
Cicatrização/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (LINGO1 protein, mouse); 0 (Lecithins); 0 (MIRN219 microRNA, mouse); 0 (Membrane Proteins); 0 (MicroRNAs); 0 (Mirn338 microRNA, mouse); 0 (Nerve Tissue Proteins)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170826
[Lr] Data última revisão:
170826
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170329
[St] Status:MEDLINE


  8 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28294260
[Au] Autor:Patel AR
[Ad] Endereço:Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, 9000 Gent, Belgium. ashok.2510@gmail.com ashok.patel@inl.int.
[Ti] Título:Stable 'arrested' non-aqueous edible foams based on food emulsifiers.
[So] Source:Food Funct;8(6):2115-2120, 2017 Jun 21.
[Is] ISSN:2042-650X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Stable oil foams with structured air-oil interfaces and high overrun (φ ≫ 0.5) were fabricated using edible emulsifiers (sucrose esters and lecithin). Advanced microscopy was used to understand the microstructure of these 'arrested' non-aqueous foams which displayed interesting rheological behaviour (yielding and thixotropy). Such complex colloids stabilized by edible ingredients could find important industrial applications in the development of novel textured food products.
[Mh] Termos MeSH primário: Emulsificantes/química
[Mh] Termos MeSH secundário: Coloides/química
Ésteres/química
Tecnologia de Alimentos
Lecitinas/química
Reologia
Sacarose/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Colloids); 0 (Emulsifying Agents); 0 (Esters); 0 (Lecithins); 57-50-1 (Sucrose)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170316
[St] Status:MEDLINE
[do] DOI:10.1039/c7fo00187h


  9 / 761 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28199856
[Au] Autor:Nouraei M; Acosta EJ
[Ad] Endereço:University of Toronto, Department of Chemical Engineering and Applied Chemistry, 200 College Street, Room 131, Toronto, Ontario M5S 3E5, Canada.
[Ti] Título:Predicting solubilisation features of ternary phase diagrams of fully dilutable lecithin linker microemulsions.
[So] Source:J Colloid Interface Sci;495:178-190, 2017 06 01.
[Is] ISSN:1095-7103
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fully dilutable microemulsions (µEs), used to design self-microemulsifying delivery system (SMEDS), are formulated as concentrate solutions containing oil and surfactants, without water. As water is added to dilute these systems, various µEs are produced (water-swollen reverse micelles, bicontinuous systems, and oil-swollen micelles), without the onset of phase separation. Currently, the formulation dilutable µEs follows a trial and error approach that has had a limited success. The objective of this work is to introduce the use of the hydrophilic-lipophilic-difference (HLD) and net-average-curvature (NAC) frameworks to predict the solubilisation features of ternary phase diagrams of lecithin-linker µEs and the use of these predictions to guide the formulation of dilutable µEs. To this end, the characteristic curvatures (Cc) of soybean lecithin (surfactant), glycerol monooleate (lipophilic linker) and polyglycerol caprylate (hydrophilic linker) and the equivalent alkane carbon number (EACN) of ethyl caprate (oil) were obtained via phase scans with reference surfactant-oil systems. These parameters were then used to calculate the HLD of lecithin-linkers-ethyl caprate microemulsions. The calculated HLDs were able to predict the phase transitions observed in the phase scans. The NAC was then used to fit and predict phase volumes obtained from salinity phase scans, and to predict the solubilisation features of ternary phase diagrams of the lecithin-linker formulations. The HLD-NAC predictions were reasonably accurate, and indicated that the largest region for dilutable µEs was obtained with slightly negative HLD values. The NAC framework also predicted, and explained, the changes in microemulsion properties along dilution lines.
[Mh] Termos MeSH primário: Portadores de Fármacos/química
Lecitinas/química
[Mh] Termos MeSH secundário: Composição de Medicamentos
Emulsões
Interações Hidrofóbicas e Hidrofílicas
Micelas
Tamanho da Partícula
Transição de Fase
Solubilidade
Propriedades de Superfície
Tensoativos/química
Viscosidade
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Drug Carriers); 0 (Emulsions); 0 (Lecithins); 0 (Micelles); 0 (Surface-Active Agents); 059QF0KO0R (Water)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170921
[Lr] Data última revisão:
170921
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170216
[St] Status:MEDLINE


  10 / 761 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28193410
[Au] Autor:Pires LN; Brandão GC; Teixeira LS
[Ad] Endereço:Universidade Federal da Bahia, Instituto de Química, Departamento de Química Analítica, Campus Universitário de Ondina, 40170-115 Salvador, Bahia, Brazil.
[Ti] Título:Determination of phospholipids in soybean lecithin samples via the phosphorus monoxide molecule by high-resolution continuum source graphite furnace molecular absorption spectrometry.
[So] Source:Food Chem;225:162-166, 2017 Jun 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This paper presents a method for determining phospholipids in soybean lecithin samples by phosphorus determination using high-resolution continuum source graphite furnace molecular absorption spectrometry (HR-CS GF MAS) via molecular absorption of phosphorus monoxide. Samples were diluted in methyl isobutyl ketone. The best conditions were found to be 213.561nm with a pyrolysis temperature of 1300°C, a volatilization temperature of 2300°C and Mg as a chemical modifier. To increase the analytical sensitivity, measurement of the absorbance signal was obtained by summing molecular transition lines for PO surrounding 213nm: 213.561, 213.526, 213.617 and 213.637nm. The limit of detection was 2.35mgg and the precision, evaluated as relative standard deviation (RSD), was 2.47% (n=10) for a sample containing 2.2% (w/v) phosphorus. The developed method was applied for the analysis of commercial samples of soybean lecithin. The determined concentrations of phospholipids in the samples varied between 38.1 and 45% (w/v).
[Mh] Termos MeSH primário: Lecitinas/análise
Fosfolipídeos/análise
Fósforo/análise
Feijão de Soja/química
Espectrofotometria Atômica/métodos
[Mh] Termos MeSH secundário: Grafite
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Lecithins); 0 (Phospholipids); 27YLU75U4W (Phosphorus); 7782-42-5 (Graphite)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170504
[Lr] Data última revisão:
170504
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170215
[St] Status:MEDLINE



página 1 de 77 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde