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[PMID]:29327928
[Au] Autor:Zhu ZJ; Chen HM; Chen JJ; Yang R; Yan XJ
[Ad] Endereço:Key Laboratory of Marine Biotechnology of Zhejiang Province, Ningbo University , Ningbo, Zhejiang 315211, China.
[Ti] Título:One-Step Bioconversion of Fatty Acids into C8-C9 Volatile Aroma Compounds by a Multifunctional Lipoxygenase Cloned from Pyropia haitanensis.
[So] Source:J Agric Food Chem;66(5):1233-1241, 2018 Feb 07.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The multifunctional lipoxygenase PhLOX cloned from Pyropia haitanensis was expressed in Escherichia coli with 24.4 mg·L yield. PhLOX could catalyze the one-step bioconversion of C18-C22 fatty acids into C8-C9 volatile organic compounds (VOCs), displaying higher catalytic efficiency for eicosenoic and docosenoic acids than for octadecenoic acids. C20:5 was the most suitable substrate among the tested fatty acids. The C8-C9 VOCs were generated in good yields from fatty acids, e.g., 2E-nonenal from C20:4, and 2E,6Z-nonadienal from C20:5. Hydrolyzed oils were also tested as substrates. The reactions mainly generated 2E,4E-pentadienal, 2E-octenal, and 2E,4E-octadienal from hydrolyzed sunflower seed oil, corn oil, and fish oil, respectively. PhLOX showed good stability after storage at 4 °C for 2 weeks and broad tolerance to pH and temperature. These desirable properties of PhLOX make it a promising novel biocatalyst for the industrial production of volatile aroma compounds.
[Mh] Termos MeSH primário: Ácidos Graxos/metabolismo
Lipoxigenase/genética
Lipoxigenase/metabolismo
Proteínas Recombinantes/metabolismo
Rodófitas/enzimologia
Compostos Orgânicos Voláteis/metabolismo
[Mh] Termos MeSH secundário: Clonagem Molecular
Óleo de Milho/metabolismo
Estabilidade Enzimática
Ácidos Erúcicos/metabolismo
Escherichia coli/genética
Ácidos Graxos Monoinsaturados/metabolismo
Óleos de Peixe/metabolismo
Expressão Gênica
Concentração de Íons de Hidrogênio
Rodófitas/genética
Especificidade por Substrato
Óleo de Girassol/metabolismo
Temperatura Ambiente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Erucic Acids); 0 (Fatty Acids); 0 (Fatty Acids, Monounsaturated); 0 (Fish Oils); 0 (Recombinant Proteins); 0 (Sunflower Oil); 0 (Volatile Organic Compounds); 8001-30-7 (Corn Oil); EC 1.13.11.12 (Lipoxygenase); UDX6WPL94T (eicosenoic acid)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b05341


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[PMID]:29364913
[Au] Autor:Mellouk N; Ramé C; Marchand M; Staub C; Touzé JL; Venturi É; Mercerand F; Travel A; Chartrin P; Lecompte F; Ma L; Froment P; Dupont J
[Ad] Endereço:INRA UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France.
[Ti] Título:Effect of different levels of feed restriction and fish oil fatty acid supplementation on fat deposition by using different techniques, plasma levels and mRNA expression of several adipokines in broiler breeder hens.
[So] Source:PLoS One;13(1):e0191121, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Reproductive hens are subjected to a restricted diet to limit the decline in fertility associated with change in body mass. However, endocrine and tissue responses to diet restriction need to be documented. OBJECTIVE: We evaluated the effect of different levels of feed restriction, with or without fish oil supplementation, on metabolic parameters and adipokine levels in plasma and metabolic tissues of reproductive hens. METHODS: We designed an in vivo protocol involving 4 groups of hens; RNS: restricted (Rt) unsupplemented, ANS: ad libitum (Ad, receiving an amount of feed 1.7 times greater than animals on the restricted diet) unsupplemented, RS: Rt supplemented, and AS: Ad supplemented. The fish oil supplement was used at 1% of the total diet composition. RESULTS: Hens fed with the Rt diet had a significantly (P < 0.0001) lower growth than Ad hens, while the fish oil supplementation had no effect on these parameters. Furthermore, the bioelectrical impedance analysis (BIA) and the fat ultrasonographic examinations produced similar results to the other methods that required animals to be killed (carcass analysis and weight of adipose tissue). In addition, the Rt diet significantly (P < 0.05) decreased plasma levels of triglycerides, phospholipids, glucose and ADIPOQ, and fish oil supplementation decreased plasma levels of RARRES2. We also showed a positive correlation between insulin values and ADIPOQ or NAMPT or RARRES2 values, and a negative correlation of fat percentage to RARRES2 values. Moreover, the effects of the Rt diet and fish oil supplementation on the mRNA expression depended on the factors tested and the hen age. CONCLUSIONS: Rt diet and fish oil supplementation are able to modulate metabolic parameters and the expression of adipokines and their receptors in metabolic tissue.
[Mh] Termos MeSH primário: Adipocinas/sangue
Ração Animal
Restrição Calórica
Ácidos Graxos/administração & dosagem
Óleos de Peixe/administração & dosagem
RNA Mensageiro/genética
[Mh] Termos MeSH secundário: Adipocinas/genética
Animais
Galinhas
Gema de Ovo/metabolismo
Ácidos Graxos/metabolismo
Feminino
Fígado/metabolismo
Músculos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Adipokines); 0 (Fatty Acids); 0 (Fish Oils); 0 (RNA, Messenger)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180223
[Lr] Data última revisão:
180223
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191121


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[PMID]:29364933
[Au] Autor:Lazzarotto V; Médale F; Larroquet L; Corraze G
[Ad] Endereço:INRA - UMR 1419 "Nutrition Métabolisme Aquaculture", Aquapôle, Saint Pée-sur-Nivelle, France.
[Ti] Título:Long-term dietary replacement of fishmeal and fish oil in diets for rainbow trout (Oncorhynchus mykiss): Effects on growth, whole body fatty acids and intestinal and hepatic gene expression.
[So] Source:PLoS One;13(1):e0190730, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The effects of replacing fishmeal and fish oil with a plant-based diet were studied in juvenile (10g) and ongrowing (250-350g) rainbow trout from first-feeding. Feed-related differences in the intestinal and hepatic transcriptome were examined in juveniles after 7 months of feeding at 7°C. Based on microarray results obtained for juveniles, the expression of selected genes related to lipid, cholesterol and energy metabolisms, was assessed by RT-qPCR in ongrowing trout after 6 additional months of feeding at 17°C. Plasma glucose and cholesterol, lipid content and fatty acid profile of whole body were analyzed at both stages. After 7 months at 7°C, all juveniles reached the same body weight (10g), while at 13 months ongrowing fish fed the totally plant-based diet exhibited lower body weight (234 vs 330-337g). Body lipid content was higher in juveniles fed the totally plant-based diet (13.2 vs 9.4-9.9%), and plasma cholesterol was about 2-times lower in trout fed the plant-based diets at both stages. Fatty acid profile mirrored that of the respective diet, with low proportions of long-chain n-3 polyunsaturated fatty acids in fish fed plant-based diets. Genes involved in protein catabolism, carbohydrate metabolism and trafficking were down-regulated in the intestines of juveniles fed the plant-based diets. This was not true for ongrowing fish. Genes involved in lipid and cholesterol metabolisms were up-regulated in the livers of fish fed plant-based diets for both stages. In this study, feeding trout a totally plant-based diet from first-feeding affect a relatively low proportion of metabolism-related genes. In the longer term, when fish were reared at a higher temperature, only some of these changes were maintained (i.e. up-regulation of lipid/cholesterol metabolism). Although the plant-based diets tested in this study had no major deficiencies, small adjustments in the feed-formula are needed to further optimize growth performance while sparing marine resources.
[Mh] Termos MeSH primário: Ração Animal
Óleos de Peixe/administração & dosagem
Intestinos/metabolismo
Fígado/metabolismo
Oncorhynchus mykiss/metabolismo
[Mh] Termos MeSH secundário: Animais
Colesterol/sangue
Metabolismo Energético
Expressão Gênica
Metabolismo dos Lipídeos
Análise de Sequência com Séries de Oligonucleotídeos
Oncorhynchus mykiss/genética
Oncorhynchus mykiss/crescimento & desenvolvimento
Reação em Cadeia da Polimerase em Tempo Real
Transcriptoma
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Fish Oils); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190730


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[PMID]:29232116
[Au] Autor:Zhang Z; Liu F; Ma X; Huang H; Wang Y
[Ad] Endereço:School of Food Science and Engineering, South China University of Technology , Guangzhou 510641, China.
[Ti] Título:Two-Stage Enzymatic Preparation of Eicosapentaenoic Acid (EPA) And Docosahexaenoic Acid (DHA) Enriched Fish Oil Triacylglycerols.
[So] Source:J Agric Food Chem;66(1):218-227, 2018 Jan 10.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Fish oil products in the form of triacylglycerols generally have relatively low contents of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and so it is of potential research and industrial interest to enrich the related contents in commercial products. Thereby an economical and efficient two-stage preparation of EPA and DHA enriched fish oil triacylglycerols is proposed in this study. The first stage was the partial hydrolysis of fish oil by only 0.2 wt.‰ AY "Amano" 400SD which led to increases of EPA and DHA contents in acylglycerols from 19.30 and 13.09 wt % to 25.95 and 22.06 wt %, respectively. Subsequently, products of the first stage were subjected to transesterification with EPA and DHA enriched fatty acid ethyl esters (EDEE) as the second stage to afford EPA and DHA enriched fish oil triacylglycerols by using as low as 2 wt % Novozyme 435. EDEEs prepared from fish oil ethyl ester, and recycled DHA and EPA, respectively, were applied in this stage. Final products prepared with two different sources of EDEEs were composed of 97.62 and 95.92 wt % of triacylglycerols, respectively, with EPA and DHA contents of 28.20 and 21.41 wt % for the former and 25.61 and 17.40 wt % for the latter. Results not only demonstrate this two-stage process's capability and industrial value for enriching EPA and DHA in fish oil products, but also offer new opportunities for the development of fortified fish oil products.
[Mh] Termos MeSH primário: Ácidos Docosa-Hexaenoicos/química
Ácido Eicosapentaenoico/química
Óleos de Peixe/química
Tecnologia de Alimentos/métodos
Lipase/química
Triglicerídeos/química
[Mh] Termos MeSH secundário: Animais
Biocatálise
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fish Oils); 0 (Triglycerides); 25167-62-8 (Docosahexaenoic Acids); AAN7QOV9EA (Eicosapentaenoic Acid); EC 3.1.1.- (Novozyme 435); EC 3.1.1.3 (Lipase)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180205
[Lr] Data última revisão:
180205
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b04101


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[PMID]:28946274
[Au] Autor:Morales-Medina R; Munio M; Guadix A; Guadix EM; Camacho F
[Ad] Endereço:Department of Chemical Engineering, University of Granada, 18071 Granada, Spain. Electronic address: rocio_morales@ugr.es.
[Ti] Título:A lumped model of the lipase catalyzed hydrolysis of sardine oil to maximize polyunsaturated fatty acids content in acylglycerols.
[So] Source:Food Chem;240:286-294, 2018 Feb 01.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The aim of this work was to produce diacylglycerols (DAG) and monoacylglycerols (MAG) with a high content of polyunsaturated fatty acids (PUFA). Rhizomucor miehei lipase mediated-hydrolysis of sardine oil was conducted at several water activities. The system was mechanistically modeled to predict the time evolution of the concentration of triacylglycerols, DAG, MAG and free fatty acids (FFA) and the concentration of saturated, mono- and polyunsaturated fatty acids. The release of the first fatty acid from the triacylglycerol was independent on the unsaturation degree. Contrary, the hydrolysis of the second one was highly affected by the degree of unsaturation, PUFA being the fatty acids that showed the highest resistance to hydrolysis. MAG percentage was maximum (7mol%) at lower water activities, while DAG content was favored at higher water activities (35mol%), achieving a 2-fold concentration of DHA.
[Mh] Termos MeSH primário: Óleos de Peixe/metabolismo
Lipase/metabolismo
[Mh] Termos MeSH secundário: Animais
Ácidos Graxos
Ácidos Graxos Insaturados
Peixes
Glicerídeos
Hidrólise
Rhizomucor
Triglicerídeos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Fatty Acids, Unsaturated); 0 (Fish Oils); 0 (Glycerides); 0 (Triglycerides); EC 3.1.1.3 (Lipase)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170927
[St] Status:MEDLINE


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[PMID]:28873646
[Au] Autor:Cascant MM; Breil C; Fabiano-Tixier AS; Chemat F; Garrigues S; de la Guardia M
[Ad] Endereço:Department of Analytical Chemistry, University of Valencia, 50 Dr. Moliner Street, Research Building, 46100 Burjassot, Valencia, Spain; Université d'Avignon et des Pays de Vaucluse, INRA, UMR408, GREEN Team Extraction, 84000 Avignon Cedex, France.
[Ti] Título:Determination of fatty acids and lipid classes in salmon oil by near infrared spectroscopy.
[So] Source:Food Chem;239:865-871, 2018 Jan 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Near-infrared (NIR) spectroscopy was evaluated as a rapid method for the determination of oleic, palmitic, linoleic and linolenic acids as well as omega-3, omega-6, and to predict polyunsaturated, monounsaturated and saturated fatty acids, together with triacylglycerides, diglycerides, free fatty acids and ergosterol in salmon oil. To do it, Partial Least Squares (PLS) regression models were applied to correlate NIR spectra with aforementioned fatty acids and lipid classes. Results obtained were validated in front of reference procedures based on high performance thin layer and gas chromatography. PLS-NIR has a good predictive capability with relative root mean square error of prediction (RRMSEP) values below or equal to 1.8% and provides rapid analysis without the use of any chemicals making it an environmentally friendly methodology.
[Mh] Termos MeSH primário: Óleos de Peixe/química
[Mh] Termos MeSH secundário: Ácidos Graxos
Análise dos Mínimos Quadrados
Espectroscopia de Luz Próxima ao Infravermelho
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Fish Oils); 68991-43-5 (salmon oil)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE


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[PMID]:28873574
[Au] Autor:Owens C; Griffin K; Khouryieh H; Williams K
[Ad] Endereço:Department of Chemistry, Western Kentucky University, Bowling Green, KY, USA.
[Ti] Título:Creaming and oxidative stability of fish oil-in-water emulsions stabilized by whey protein-xanthan-locust bean complexes: Impact of pH.
[So] Source:Food Chem;239:314-322, 2018 Jan 15.
[Is] ISSN:0308-8146
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The impact of pH on the physicochemical properties of 10% menhaden oil-in-water (O/W) emulsions containing 2% whey protein isolate (WPI) and 0.1% xanthan (XG)-locust bean gum (LBG) mixtures was investigated. The O/W emulsions containing 0.1% XG-LBG mixtures were compared to emulsions with 0.1% XG and 0.1% LBG. The results indicated that stability is dependent on pH and biopolymer type. At both pH 3 and 5, emulsions containing either XG or XG-LBG mixtures had large particle sizes, viscosity, droplet aggregation, and creaming index, resulting in poor physical stability which can be related to the adsorbed protein-polysaccharide interactions. At pH7, the XG-LBG emulsions showed the greatest resistance to phase separation and resulted in stable emulsions. Lipid oxidation measurements also indicated that XG-LBG mixtures can be used to form stable emulsions at pH 3 and pH 7. These results have significant implications for the development of novel structures containing lipid phases susceptible to lipid oxidation.
[Mh] Termos MeSH primário: Óleos de Peixe/química
[Mh] Termos MeSH secundário: Animais
Emulsões
Galactanos
Gafanhotos
Concentração de Íons de Hidrogênio
Mananas
Gomas Vegetais
Polissacarídeos Bacterianos
Água
Proteínas do Soro do Leite
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Emulsions); 0 (Fish Oils); 0 (Galactans); 0 (Mannans); 0 (Plant Gums); 0 (Polysaccharides, Bacterial); 0 (Whey Proteins); 059QF0KO0R (Water); TTV12P4NEE (xanthan gum); V4716MY704 (locust bean gum)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170907
[St] Status:MEDLINE


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[PMID]:29059226
[Au] Autor:Callet T; Médale F; Larroquet L; Surget A; Aguirre P; Kerneis T; Labbé L; Quillet E; Geurden I; Skiba-Cassy S; Dupont-Nivet M
[Ad] Endereço:UMR GABI, INRA, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.
[Ti] Título:Successful selection of rainbow trout (Oncorhynchus mykiss) on their ability to grow with a diet completely devoid of fishmeal and fish oil, and correlated changes in nutritional traits.
[So] Source:PLoS One;12(10):e0186705, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:In the context of limited marine resources, the exponential growth of aquaculture requires the substitution of fish oil and fishmeal, the traditional components of fish feeds by terrestrial plant ingredients. High levels of such substitution are known to negatively impact fish performance such as growth and survival in rainbow trout (Oncorhynchus mykiss) as in other salmonids. In this respect, genetic selection is a key enabler for improving those performances and hence for the further sustainable development of aquaculture. We selected a rainbow trout line over three generations for its ability to survive and grow on a 100% plant-based diet devoid of both fish oil and fishmeal (V diet) from the very first meal. In the present study, we compared the control line and the selected line after 3 generations of selection, both fed either the V diet or a marine resources-based diet (M diet). The objective of the study was to assess the efficiency of selection and the consequences on various correlated nutritional traits: feed intake, feed efficiency, digestibility, composition of whole fish, nutrient retention and fatty acid (FA) profile. We demonstrated that the genetic variability present in our rainbow trout population can be selected to improve survival and growth. The major result of the study is that after only three generations of selection, selected fish fed the V diet grew at the same rate as the control line fed the M diet, whilst the relative reduction of body weight was 36.8% before the selection. This enhanced performance on the V diet seems to be mostly linked to a higher feed intake for the selected fish.
[Mh] Termos MeSH primário: Ração Animal
Óleos de Peixe
Peixes
Oncorhynchus mykiss/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fish Oils)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171113
[Lr] Data última revisão:
171113
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171024
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186705


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[PMID]:29016689
[Au] Autor:Cui C; Li Y; Gao H; Zhang H; Han J; Zhang D; Li Y; Zhou J; Lu C; Su X
[Ad] Endereço:School of Marine Science, Ningbo University, Ningbo, Zhejiang, China.
[Ti] Título:Modulation of the gut microbiota by the mixture of fish oil and krill oil in high-fat diet-induced obesity mice.
[So] Source:PLoS One;12(10):e0186216, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Previous studies confirmed that dietary supplements of fish oil and krill oil can alleviate obesity in mice, but the underlying mechanism remains unclear. This study aims to discern whether oil treatment change the structure of the gut microbiota during the obesity alleviation. The ICR mice received high-fat diet (HFD) continuously for 12 weeks after two weeks of acclimatization with a standard chow diet, and the mice fed with a standard chow diet were used as the control. In the groups that received HFD with oil supplementation, the weight gains were attenuated and the liver index, total cholesterol, triglyceride and low-density lipoprotein cholesterol were reduced stepwise compared with the HFD group, and the overall structure of the gut microbiota, which was modulated in the HFD group, was shifted toward the structure found in the control group. Moreover, eighty-two altered operational taxonomic units responsive to oil treatment were identified and nineteen of them differing in one or more parameters associated with obesity. In conclusion, this study confirmed the effect of oil treatment on obesity alleviation, as well as on the microbiota structure alterations. We proposed that further researches are needed to elucidate the causal relationship between obesity alleviation and gut microbiota modulation.
[Mh] Termos MeSH primário: Microbioma Gastrointestinal/genética
Fígado/efeitos dos fármacos
Obesidade/dietoterapia
[Mh] Termos MeSH secundário: Animais
Colesterol/metabolismo
Dieta Hiperlipídica/efeitos adversos
Euphausiacea/química
Óleos de Peixe/administração & dosagem
Microbioma Gastrointestinal/efeitos dos fármacos
Seres Humanos
Lipoproteínas LDL/metabolismo
Fígado/metabolismo
Fígado/patologia
Camundongos
Camundongos Obesos
Obesidade/microbiologia
Obesidade/patologia
Triglicerídeos/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fish Oils); 0 (Lipoproteins, LDL); 0 (Triglycerides); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171031
[Lr] Data última revisão:
171031
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171011
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0186216


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[PMID]:28965514
[Au] Autor:Turkmen S; Zamorano MJ; Fernández-Palacios H; Hernández-Cruz CM; Montero D; Robaina L; Izquierdo M
[Ad] Endereço:Aquaculture Research Group (GIA),Research Institute in Sustainable Aquaculture and Marine Conservation (IU-ECOAQUA),Universidad de Las Palmas de Gran Canaria,Crta. Taliarte s/n,35214 Telde,Spain.
[Ti] Título:Parental nutritional programming and a reminder during juvenile stage affect growth, lipid metabolism and utilisation in later developmental stages of a marine teleost, the gilthead sea bream (Sparus aurata).
[So] Source:Br J Nutr;118(7):500-512, 2017 Oct.
[Is] ISSN:1475-2662
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Nutrition during periconception and early development can modulate metabolic routes to prepare the offspring for adverse conditions through a process known as nutritional programming. In gilthead sea bream, replacement of fish oil (FO) with linseed oil (LO) in broodstock diets improves growth in the 4-month-old offspring challenged with low-FO and low-fishmeal (FM) diets for 1 month. The present study further investigated the effects of broodstock feeding on the same offspring when they were 16 months old and were challenged for a second time with the low-FM and low-FO diet for 2 months. The results showed that replacement of parental moderate-FO feeding with LO, combined with juvenile feeding at 4 months old with low-FM and low-FO diets, significantly (P<0·05) improved offspring growth and feed utilisation of low-FM/FO diets even when they were 16 months old: that is, when they were on the verge of their first reproductive season. Liver fatty acid composition was significantly affected by broodstock or reminder diets as well as by their interaction. Moreover, the reduction of long-chain PUFA and increase in α-linolenic acid and linoleic acid in broodstock diets lead to a significant down-regulation of hepatic lipoprotein lipase (P<0·001) and elongation of very long-chain fatty acids protein 6 (P<0·01). Besides, fatty acid desaturase 2 values were positively correlated to hepatic levels of 18 : 4n-3, 18 : 3n-6, 20 : 5n-3, 22 : 6n-3 and 22 : 5n-6. Thus, this study demonstrated the long-term nutritional programming of gilthead sea bream through broodstock feeding, the effect of feeding a 'reminder' diet during juvenile stages to improve utilisation of low-FM/FO diets and fish growth as well as the regulation of gene expression along the fish's life-cycle.
[Mh] Termos MeSH primário: Ração Animal/análise
Dieta/veterinária
Metabolismo dos Lipídeos
Dourada/crescimento & desenvolvimento
[Mh] Termos MeSH secundário: Animais
Regulação para Baixo
Ácidos Graxos Dessaturases/genética
Ácidos Graxos Dessaturases/metabolismo
Ácidos Graxos/administração & dosagem
Ácidos Graxos Insaturados/administração & dosagem
Óleos de Peixe/administração & dosagem
Ácido Linoleico/administração & dosagem
Óleo de Semente do Linho/administração & dosagem
Lipase Lipoproteica/genética
Lipase Lipoproteica/metabolismo
Fígado/metabolismo
Ácido alfa-Linolênico/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fatty Acids); 0 (Fatty Acids, Unsaturated); 0 (Fish Oils); 0RBV727H71 (alpha-Linolenic Acid); 8001-26-1 (Linseed Oil); 9KJL21T0QJ (Linoleic Acid); EC 1.14.19.- (Fatty Acid Desaturases); EC 3.1.1.34 (Lipoprotein Lipase)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171017
[Lr] Data última revisão:
171017
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171003
[St] Status:MEDLINE
[do] DOI:10.1017/S0007114517002434



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