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[PMID]:28314390
[Au] Autor:Schrack S; Hohl C; Schwack W
[Ad] Endereço:State Laboratory of the Canton Basel-City, CH-4056 Basel, Switzerland. Electronic address: sonja.schrack@bs.ch.
[Ti] Título:Oxysterols in cosmetics-Determination by planar solid phase extraction and gas chromatography-mass spectrometry.
[So] Source:J Chromatogr A;1473:10-18, 2016 Nov 18.
[Is] ISSN:1873-3778
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Sterol oxidation products (SOPs) are linked to several toxicological effects. Therefore, investigation of potential dietary uptake sources particularly food of animal origin has been a key issue for these compounds. For the simultaneous determination of oxysterols from cholesterol, phytosterols, dihydrolanosterol and lanosterol in complex cosmetic matrices, planar solid phase extraction (pSPE) was applied as clean-up tool. SOPs were first separated from more non-polar and polar matrix constituents by normal phase thin-layer chromatography and then focussed into one target zone. Zone extraction was performed with the TLC-MS interface, followed by gas chromatography-mass spectrometry analysis. pSPE showed to be effective for cleaning up cosmetic samples as sample extracts were free of interferences, and gas chromatographic columns did not show any signs of overloading. Recoveries were between 86 and 113% with relative standard deviations of below 10% (n=6). Results of our market survey in 2016 showed that some cosmetics with ingredients of plant origin contained phytosterol oxidation products (POPs) in the low ppm range and therefore in line with levels reported for food. In lanolin containing products, total SOPs levels (cholesterol oxidation products (COPs), lanosterol oxidation products (LOPs), dihydrolanosterol oxidation products (DOPs)) being in the low percent range exceeded reported levels for food by several orders of magnitudes.
[Mh] Termos MeSH primário: Cosméticos/química
Cromatografia Gasosa-Espectrometria de Massas/métodos
Oxisteróis/análise
Extração em Fase Sólida/métodos
[Mh] Termos MeSH secundário: Animais
Colesterol/análise
Colesterol/metabolismo
Cromatografia em Camada Delgada
Lanolina/análise
Lanolina/metabolismo
Lanosterol/análogos & derivados
Lanosterol/análise
Lanosterol/metabolismo
Oxirredução
Oxisteróis/metabolismo
Fitosteróis/análise
Fitosteróis/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cosmetics); 0 (Oxysterols); 0 (Phytosterols); 1J05Z83K3M (Lanosterol); 8006-54-0 (Lanolin); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170404
[Lr] Data última revisão:
170404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170319
[St] Status:MEDLINE


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[PMID]:27769340
[Au] Autor:Leung VC; Belovay GW; Chan CC
[Ad] Endereço:University of Toronto, Toronto, Ont.
[Ti] Título:Tegaderm dressing and Lacri-lube ointment moisture chamber to manage exposure keratopathy.
[So] Source:Can J Ophthalmol;51(5):e149-e151, 2016 Oct.
[Is] ISSN:1715-3360
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Acidentes de Trânsito
Clorobutanol/uso terapêutico
Doenças da Córnea/terapia
Edema/terapia
Traumatismos Oculares/terapia
Doenças Palpebrais/terapia
Lanolina/uso terapêutico
Óleo Mineral/uso terapêutico
Curativos Oclusivos
[Mh] Termos MeSH secundário: Terapia Combinada
Combinação de Medicamentos
Exoftalmia/terapia
Seres Humanos
Lacerações
Masculino
Pomadas
Adulto Jovem
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
0 (Drug Combinations); 0 (Ointments); 78200-24-5 (lacri-lube); 8006-54-0 (Lanolin); 8020-83-5 (Mineral Oil); HM4YQM8WRC (Chlorobutanol)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170915
[Lr] Data última revisão:
170915
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE


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[PMID]:27478491
[Au] Autor:Erdogan S; Gülhan OT
[Ad] Endereço:Department of Biostatistics and Bioinformatics, Faculty of Medicine, Mersin University, 33343 Mersin, Turkey.
[Ti] Título:Alternative Confidence Interval Methods Used in the Diagnostic Accuracy Studies.
[So] Source:Comput Math Methods Med;2016:7141050, 2016.
[Is] ISSN:1748-6718
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Background/Aim. It is necessary to decide whether the newly improved methods are better than the standard or reference test or not. To decide whether the new diagnostics test is better than the gold standard test/imperfect standard test, the differences of estimated sensitivity/specificity are calculated with the help of information obtained from samples. However, to generalize this value to the population, it should be given with the confidence intervals. The aim of this study is to evaluate the confidence interval methods developed for the differences between the two dependent sensitivity/specificity values on a clinical application. Materials and Methods. In this study, confidence interval methods like Asymptotic Intervals, Conditional Intervals, Unconditional Interval, Score Intervals, and Nonparametric Methods Based on Relative Effects Intervals are used. Besides, as clinical application, data used in diagnostics study by Dickel et al. (2010) has been taken as a sample. Results. The results belonging to the alternative confidence interval methods for Nickel Sulfate, Potassium Dichromate, and Lanolin Alcohol are given as a table. Conclusion. While preferring the confidence interval methods, the researchers have to consider whether the case to be compared is single ratio or dependent binary ratio differences, the correlation coefficient between the rates in two dependent ratios and the sample sizes.
[Mh] Termos MeSH primário: Testes Diagnósticos de Rotina/métodos
Testes Diagnósticos de Rotina/normas
[Mh] Termos MeSH secundário: Álcoois
Algoritmos
Alérgenos
Simulação por Computador
Intervalos de Confiança
Coleta de Dados
Interpretação Estatística de Dados
Seres Humanos
Lanolina
Funções Verossimilhança
Modelos Estatísticos
Níquel
Dicromato de Potássio
Reprodutibilidade dos Testes
Tamanho da Amostra
Sensibilidade e Especificidade
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alcohols); 0 (Allergens); 4FLT4T3WUN (nickel sulfate); 7OV03QG267 (Nickel); 8006-54-0 (Lanolin); T4423S18FM (Potassium Dichromate)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170310
[Lr] Data última revisão:
170310
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160802
[St] Status:MEDLINE
[do] DOI:10.1155/2016/7141050


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[PMID]:27126752
[Au] Autor:Goldman M; Lodhi I
[Ad] Endereço:Chief Medical Officer, Iatros Consulting, London.
[Ti] Título:A real-world evidence study evaluating a treatment for nappy rash.
[So] Source:Br J Nurs;25(8):432-9, 2016 Apr 28-May 11.
[Is] ISSN:0966-0461
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:This retrospective open study evaluating the efficacy of Sudocrem Antiseptic Healing Cream (SAHC) in infantile nappy rash (NR) was based on real-world evidence collected using an online questionnaire that included Likert scales. Participants who had used SAHC in the past (n=2159) were recruited via social media and email. A total of 1818 respondents who had treated NR in the previous 6 months were asked to take part in the study. Over 50% of respondents saw an improvement in NR on the same day that treatment was started, and within 3 days 94.5% of respondents reported an improvement in NR. Of 1804 subjects who answered the question, 72.5% indicated that the NR had completely healed within 3 days of starting treatment and by the fifth day, 94.7% said that the NR had completely healed. A total of 71% of 1793 respondents said that an episode of NR had either no or minimal impact disrupting their normal lives, but 29% reported a noticeable impact, even though evidence suggests that mild to moderate nappy rash can be treated quickly. Based on this real-world retrospective study, the evidence suggests SAHC is rapidly effective, reduces signs and symptoms of inflammation, and heals NR.
[Mh] Termos MeSH primário: Anestésicos Locais/uso terapêutico
Anti-Infecciosos Locais/uso terapêutico
Dermatite das Fraldas/tratamento farmacológico
Emolientes/uso terapêutico
Creme para a Pele/uso terapêutico
[Mh] Termos MeSH secundário: Benzoatos/uso terapêutico
Álcool Benzílico/uso terapêutico
Compostos de Benzil/uso terapêutico
Pré-Escolar
Cinamatos/uso terapêutico
Fármacos Dermatológicos/uso terapêutico
Edema
Eritema
Feminino
Temperatura Alta
Seres Humanos
Lactente
Recém-Nascido
Inflamação
Lanolina/uso terapêutico
Masculino
Dor
Estudos Retrospectivos
Inquéritos e Questionários
Resultado do Tratamento
Cicatrização
Óxido de Zinco/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics, Local); 0 (Anti-Infective Agents, Local); 0 (Benzoates); 0 (Benzyl Compounds); 0 (Cinnamates); 0 (Dermatologic Agents); 0 (Emollients); 8006-54-0 (Lanolin); LKG8494WBH (Benzyl Alcohol); N863NB338G (benzyl benzoate); SOI2LOH54Z (Zinc Oxide); V67O3RO97U (benzyl cinnamate)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:160429
[Lr] Data última revisão:
160429
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:160430
[St] Status:MEDLINE
[do] DOI:10.12968/bjon.2016.25.8.432


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[PMID]:26927034
[Au] Autor:Pereira TA; Guerreiro CM; Maruno M; Ferrari M; Rocha-Filho PA
[Ad] Endereço:Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Bairro Monte Alegre, Ribeirão Preto, SP 14040-903, Brazil. tatianapereira1@gmail.com.
[Ti] Título:Exotic Vegetable Oils for Cosmetic O/W Nanoemulsions: In Vivo Evaluation.
[So] Source:Molecules;21(3):248, 2016 Feb 24.
[Is] ISSN:1420-3049
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Oil-in-water nanoemulsions are stable systems with droplet sizes in the 20-200 nm range. The physicochemical properties of these systems may be influenced by the addition of additives. Thus, the influence of ethoxylated (EL) and acetylated lanolin (AL) addition on the droplet size, pH values, electrical conductivity and stability of nanoemulsions was investigated. Then, effect of nano-emulsions additives with EL (NE-EL) or AL (NE-AL) in hydration, oiliness and pH of the skin were evaluated. Nanoemulsion safety was evaluated through the observation of no undesirable effects after skin formulation application. Both additives caused changes in droplet size and electrical conductivity, but not in pH values. Nanoemulsions containing up to 6.0% ethoxylated lanolin and 2.0% acetylated lanolin remained stable after centrifugation tests. Higher concentrations of the additives made the nanoemulsions unstable. Stability tests showed that ethoxylated lanolin produced more stable nanoemulsions then acetylated lanolin and that the major instability phenomenon occurring in these systems is coalescence at elevated temperatures. Nanoemulsion-based lanolin derivatives increased skin hydration and oiliness and did not change cutaneous pH values. These formulations are non-toxic since they did not cause any irritation on the skin surface after nanoemulsion application, showing potential as carriers for pharmaceuticals and cosmetic applications.
[Mh] Termos MeSH primário: Cosméticos/química
Lanolina/química
Nanoestruturas/química
Óleos Vegetais/química
Água/metabolismo
[Mh] Termos MeSH secundário: Acetilação
Adulto
Transporte Biológico
Cosméticos/farmacocinética
Estabilidade de Medicamentos
Condutividade Elétrica
Emulsões
Feminino
Temperatura Alta
Seres Humanos
Concentração de Íons de Hidrogênio
Lanolina/farmacocinética
Tamanho da Partícula
Óleos Vegetais/farmacocinética
Polietilenoglicóis/química
Pele/efeitos dos fármacos
Absorção Cutânea/fisiologia
Viscosidade
Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Cosmetics); 0 (Emulsions); 0 (Plant Oils); 059QF0KO0R (Water); 30IQX730WE (Polyethylene Glycols); 8006-54-0 (Lanolin)
[Em] Mês de entrada:1611
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160302
[St] Status:MEDLINE


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[PMID]:26820784
[Au] Autor:Higgins CL; Nixon RL
[Ad] Endereço:Occupational Dermatology Research and Education Centre, Skin and Cancer Foundation, Melbourne, Victoria, Australia.
[Ti] Título:Periorbital Allergic Contact Dermatitis Caused by Lanolin in a Lubricating Eye Ointment.
[So] Source:Australas J Dermatol;57(1):68-9, 2016 Feb.
[Is] ISSN:1440-0960
[Cp] País de publicação:Australia
[La] Idioma:eng
[Mh] Termos MeSH primário: Clorobutanol/efeitos adversos
Dermatite Alérgica de Contato/etiologia
Emolientes/efeitos adversos
Dermatoses Faciais/induzido quimicamente
Lanolina/efeitos adversos
Óleo Mineral/efeitos adversos
[Mh] Termos MeSH secundário: Combinação de Medicamentos
Síndromes do Olho Seco/tratamento farmacológico
Olho
Seres Humanos
Masculino
Meia-Idade
Pomadas
[Pt] Tipo de publicação:CASE REPORTS; LETTER
[Nm] Nome de substância:
0 (Drug Combinations); 0 (Emollients); 0 (Ointments); 78200-24-5 (lacri-lube); 8006-54-0 (Lanolin); 8020-83-5 (Mineral Oil); HM4YQM8WRC (Chlorobutanol)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170119
[Lr] Data última revisão:
170119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160129
[St] Status:MEDLINE
[do] DOI:10.1111/ajd.12426


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[PMID]:26206071
[Au] Autor:Schrack S; Hohl C; Schwack W; Niederer M; Roux B
[Ad] Endereço:State Laboratory of the Canton Basel-City, CH-4056, Basel, Switzerland.
[Ti] Título:Determination of cholesterol oxides by gas chromatography-flame ionization detection/mass selective detection and their occurence in lanolin-containing cosmetics and ointments.
[So] Source:Int J Cosmet Sci;38(1):93-9, 2016 Feb.
[Is] ISSN:1468-2494
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Cholesterol oxides (COPs) are thought to be of toxicological relevance in cholesterol-containing foods. For cholesterol-containing cosmetics and the like, no information is available up to this date. Therefore, the first of two main aims of this study was to develop and validate a method for determining COPs in lanolin-containing cosmetics such as lipsticks and fatty creams as well as in nipple ointments. The second aim was to study the occurrence of COPs and their concentration levels in the respective product classes. METHODS: The procedure is based on a published method for food comprising some necessary modifications. Sample preparation consisted of transesterfication, solid-phase extraction and silylation of target compounds. Separation of the derivatized COPs and their quantification were performed with gas chromatography (GC) using a flame ionization detector (FID) or a mass spectrometer (MS). RESULTS: The successful validation and the trouble-free application during the market survey showed that the method was fit for purpose. Total COP levels found were in the low per cent range (up to 3%) and surprisingly high, being many orders of magnitude higher than those published for foods. CONCLUSION: To our knowledge, we present for the first time a method for the determination of COPs in non-food consumer products. Furthermore, our study demonstrates that lanolin-containing cosmetics may be an additional exogenous source of COPs. We further show evidence, that at least part of the COPs are already formed on the sheep's wool.
[Mh] Termos MeSH primário: Colesterol/análise
Cromatografia Gasosa/métodos
Cosméticos/química
Lanolina/análise
Pomadas
[Mh] Termos MeSH secundário: Padrões de Referência
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Cosmetics); 0 (Ointments); 8006-54-0 (Lanolin); 97C5T2UQ7J (Cholesterol)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150725
[St] Status:MEDLINE
[do] DOI:10.1111/ics.12264


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[PMID]:26551610
[Au] Autor:Carter ZA; Gordon K; Cruz PD
[Ad] Endereço:From the Department of Dermatology, The University of Texas Southwestern Medical Center, Dallas, TX.
[Ti] Título:Erythroderma due to Unwitting Exposure to an Unobvious Allergen Source.
[So] Source:Dermatitis;26(6):291, 2015 Nov-Dec.
[Is] ISSN:2162-5220
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Dermatite Esfoliativa/induzido quimicamente
Dermatite Ocupacional/etiologia
Dermatoses da Mão/induzido quimicamente
Lanolina/toxicidade
[Mh] Termos MeSH secundário: Feminino
Seres Humanos
Meia-Idade
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
8006-54-0 (Lanolin)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:151110
[Lr] Data última revisão:
151110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151110
[St] Status:MEDLINE
[do] DOI:10.1097/DER.0000000000000146


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[PMID]:26309970
[Ti] Título:[Safe breast nipple care in breastfeeding].
[Ti] Título:Sichere Brustwarzenpflege in der Stillzeit..
[So] Source:Kinderkrankenschwester;34(3):114, 2015 Mar.
[Is] ISSN:0723-2276
[Cp] País de publicação:Germany
[La] Idioma:ger
[Mh] Termos MeSH primário: Aleitamento Materno
Lanolina/administração & dosagem
Mamilos
Higiene da Pele/enfermagem
[Mh] Termos MeSH secundário: Feminino
Alemanha
Seres Humanos
Lactente
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
8006-54-0 (Lanolin)
[Em] Mês de entrada:1510
[Cu] Atualização por classe:161020
[Lr] Data última revisão:
161020
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:150828
[St] Status:MEDLINE


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[PMID]:25581671
[Au] Autor:Warshaw EM; Maibach HI; Taylor JS; Sasseville D; DeKoven JG; Zirwas MJ; Fransway AF; Mathias CG; Zug KA; DeLeo VA; Fowler JF; Marks JG; Pratt MD; Storrs FJ; Belsito DV
[Ad] Endereço:From the University of Minnesota and the Minneapolis VAMC; University of California, San Francisco; Cleveland Clinic, Ohio; McGill University Health Centre, Montreal; University of Toronto, Canada; Ohio State University, Columbus; Associates in Dermatology, Fort Myers, Fla; Group Health Associates, Cincinnati, Ohio; Dartmouth Medical Center, Lebanon, NH; St. Luke's Roosevelt Hospital Center, New York, NY; Dermatology Specialists, Louisville, KY; Pennsylvania State University Hershey; University of Ottawa, Canada; Oregon Health Sciences University, Portland; and Columbia University Medical Center, New York, NY.
[Ti] Título:North American contact dermatitis group patch test results: 2011-2012.
[So] Source:Dermatitis;26(1):49-59, 2015 Jan-Feb.
[Is] ISSN:2162-5220
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Patch testing is an important diagnostic tool for assessment of allergic contact dermatitis (ACD). OBJECTIVE: This study documents the North American Contact Dermatitis Group (NACDG) patch-testing results from January 1, 2011, to December 31, 2012. METHODS: At 12 centers in North America, patients were tested in a standardized manner with a series of 70 allergens. Data were manually verified and entered into a central database. Descriptive frequencies were calculated, and trends analyzed using χ statistics. RESULTS: Four thousand two hundred thirty-eight patients were tested; of these, 2705 patients (63.8%) had at least 1 positive reaction, and 2029 (48.0%) were ultimately determined to have a primary diagnosis of ACD. Four hundred eight patients (9.6%) had occupationally related skin disease. There were 7532 positive allergic reactions. As compared with previous reporting periods (2009-2010 and 2000-2010), positive reaction rates statistically increased for 6 allergens: methylchloroisothiazolinone/methylisothiazolinone (5.0%; risk ratios [RRs]: 2.01 [1.60-2.52], 1.87 [1.61-2.18]), lanolin alcohol (4.6%; RRs 1.83 [1.45-2.30], 2.10 [1.79-2.47]), cinnamic aldehyde (3.9%; 1.69 [1.32-2.15], 1.53 [1.28-1.82]), glutaral (1.5%; 1.67 [1.13-2.48], 1.31 [1.00-1.71]), paraben mix (1.4%; 1.77 [1.16-2.69], 1.44 [1.09-1.92]), and fragrance mix I (12.1%; RRs 1.42 [1.25-1.61], 1.24 [1.14-1.36]). Compared with the previous decade, positivity rates for all formaldehyde-releasing preservatives significantly decreased (formaldehyde 6.6%; RR, 0.82 [0.73, 0.93]; quaternium-15 6.4% RR 0.75 [0.66, 0.85]; diazolidinyl urea 2.1%; RR, 0.67 [0.54, 0.84]; imidazolidinyl urea 1.6%, 0.60 [0.47, 0.77]; bronopol 1.6%; RR, 0.60 [0.46, 0.77]; DMDM hydantoin 1.6%; RR, 0.59 [0.54, 0.84]). Approximately a quarter of patients had at least 1 relevant allergic reaction to a non-NACDG allergen. In addition, approximately one-fourth to one-third of reactions detected by NACDG allergens would have been hypothetically missed by T.R.U.E. TEST (SmartPractice Denmark, Hillerød, Denmark). CONCLUSIONS: These data document the beginning of the epidemic of sensitivity to methylisothiazolinones in North America, which has been well documented in Europe. Patch testing with allergens beyond a standard screening tray is necessary for complete evaluation of occupational and nonoccupational ACD.
[Mh] Termos MeSH primário: Alérgenos/efeitos adversos
Dermatite Alérgica de Contato/diagnóstico
Dermatite Alérgica de Contato/epidemiologia
Dermatite Ocupacional/epidemiologia
Testes do Emplastro
[Mh] Termos MeSH secundário: Acroleína/efeitos adversos
Acroleína/análogos & derivados
Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Criança
Pré-Escolar
Dermatite Alérgica de Contato/etiologia
Dermatite Ocupacional/etiologia
Feminino
Formaldeído/efeitos adversos
Glutaral/efeitos adversos
Seres Humanos
Hidantoínas/efeitos adversos
Lanolina/efeitos adversos
Lanolina/análogos & derivados
Masculino
Metenamina/efeitos adversos
Metenamina/análogos & derivados
Meia-Idade
América do Norte/epidemiologia
Parabenos/efeitos adversos
Perfumes/efeitos adversos
Prevalência
Propilenoglicóis/efeitos adversos
Tiazóis/efeitos adversos
Ureia/efeitos adversos
Ureia/análogos & derivados
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Allergens); 0 (Hydantoins); 0 (Parabens); 0 (Perfume); 0 (Propylene Glycols); 0 (Thiazoles); 1HG84L3525 (Formaldehyde); 63393-93-1 (isopropyl lanolin); 6PU1E16C9W (bronopol); 7864XYD3JJ (Acrolein); 8006-54-0 (Lanolin); 8W8T17847W (Urea); BYR0546TOW (1,3-dimethylol-5,5-dimethylhydantoin); DEL7T5QRPN (5-chloro-2-methyl-4-isothiazolin-3-one); E40U03LEM0 (quaternium-15); H5RIZ3MPW4 (diazolidinylurea); J50OIX95QV (Methenamine); M629807ATL (imidazolidinyl urea); SR60A3XG0F (cinnamic aldehyde); T3C89M417N (Glutaral)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150113
[St] Status:MEDLINE
[do] DOI:10.1097/DER.0000000000000097



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