[PMID]: | 3425657 |
[Au] Autor: | Samaan NA; Schultz PN; Johnston DA; Creasy RW; Gonik B |
[Ad] Endereço: | Section of Endocrinology, University of Texas M.D. Anderson Hospital and Tumor Institute, Houston 77030. |
[Ti] Título: | Growth hormone, somatomedin C, and nonsuppressible insulin-like activity levels compared in premature, small, average birth weight, and large infants. |
[So] Source: | Am J Obstet Gynecol;157(6):1524-8, 1987 Dec. |
[Is] ISSN: | 0002-9378 |
[Cp] País de publicação: | United States |
[La] Idioma: | eng |
[Ab] Resumo: | We have investigated the relationship between growth hormone, somatomedin C, nonsuppressible insulin-like activity, weight, gestational age, and 1-minute Apgar score in newborn infants. The 153 infants were categorized as small for gestational age (n = 19), average for gestational age (n = 59), large for gestational age (n = 60), and premature (gestational age at birth, 36 weeks or less (n = 15). Our study showed that (1) growth hormone levels were elevated in premature infants and correlated with Apgar scores and birth weights; (2) somatomedin C and nonsuppressible insulin-like activity levels were significantly lower in premature than in term infants; and (3) the birth weight of all infants studied had a significant overall effect on both somatomedin C and nonsuppressible insulin-like activity levels, suggesting that these factors may be involved in fetal growth. However, because in small for gestational age infants somatomedin C and nonsuppressible insulin-like activity were similar to levels in average for gestational age infants, it is suggested that other factors may inhibit fetal growth. |
[Mh] Termos MeSH primário: |
Hormônio do Crescimento/sangue Recém-Nascido/sangue Recém-Nascido Prematuro/sangue Recém-Nascido Pequeno para a Idade Gestacional/sangue Fator de Crescimento Insulin-Like I/sangue Atividade Insulin-Like não Suprimível/análise Somatomedinas/sangue
|
[Mh] Termos MeSH secundário: |
Índice de Apgar Peso ao Nascer Sangue Fetal/análise Seres Humanos
|
[Pt] Tipo de publicação: | COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T; RESEARCH SUPPORT, U.S. GOV'T, P.H.S. |
[Nm] Nome de substância:
| 0 (Nonsuppressible Insulin-Like Activity); 0 (Somatomedins); 67763-96-6 (Insulin-Like Growth Factor I); 9002-72-6 (Growth Hormone) |
[Em] Mês de entrada: | 8802 |
[Cu] Atualização por classe: | 170908 |
[Lr] Data última revisão:
| 170908 |
[Sb] Subgrupo de revista: | AIM; IM |
[Da] Data de entrada para processamento: | 871201 |
[St] Status: | MEDLINE |
|
|