Base de dados : MEDLINE
Pesquisa : D13.444.735.544.355 [Categoria DeCS]
Referências encontradas : 19723 [refinar]
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  1 / 19723 MEDLINE  
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[PMID]:29441965
[Au] Autor:Cai Z; Liu J; Bian H; Cai J; Guo X
[Ti] Título:MiR-455 enhances adipogenic differentiation of 3T3-L1 cells through targeting uncoupling protein-1.
[So] Source:Pharmazie;71(11):625-628, 2016 Nov 02.
[Is] ISSN:0031-7144
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:Accumulating evidence suggests that microRNAs (miRNAs) play an important role in regulating the pathways in adipose tissue that control processes such as adipogenesis, insulin resistance, and inflammation. Adipogenic differentiation of preadipocytes is a complex process regulated by various factors including miRNAs and cytokines. MiR-455 is a well-known miRNA that enhances adipogenesis. Uncoupling protein-1 (UCP-1), a heparinbinding growth factor, plays a negative role in adipogenesis. In this investigation, we demonstrate that UCP-1 is a target gene of miR-455 during adipogenic differentiation in 3T3-L1 preadipocytes. MiR-455 downregulates UCP-1 expression through interaction with a target site of miR-455 in the coding region of mouse UCP-1. The rare codons upstream of the target site regulate miR-455-induced translational knockdown of UCP-1, which provides more insight into the mechanism of adipogenic differentiation. Thus, these results suggest that the acceerative adipogenic effect of miR-455 in 3T3-L1 cells is due, at least in part, to suppression of UCP-1.
[Mh] Termos MeSH primário: Adipogenia/efeitos dos fármacos
Diferenciação Celular/efeitos dos fármacos
MicroRNAs/farmacologia
Proteína Desacopladora 1/efeitos dos fármacos
[Mh] Termos MeSH secundário: Células 3T3-L1
Tecido Adiposo/citologia
Tecido Adiposo/efeitos dos fármacos
Animais
Códon
Regulação para Baixo/efeitos dos fármacos
Técnicas de Silenciamento de Genes
Genes Reporter/genética
Masculino
Camundongos
Camundongos Endogâmicos C57BL
Proteína Desacopladora 1/biossíntese
Proteína Desacopladora 1/genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon); 0 (MIRN455 microRNA, mouse); 0 (MicroRNAs); 0 (Ucp1 protein, mouse); 0 (Uncoupling Protein 1)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180215
[St] Status:MEDLINE
[do] DOI:10.1691/ph.2016.6734


  2 / 19723 MEDLINE  
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[PMID]:29385205
[Au] Autor:Di Paola N; Freire CCM; Zanotto PMA
[Ad] Endereço:Laboratory of Molecular Evolution and Bioinformatics, Department of Microbiology, Biomedical Sciences Institute, University of Sao Paulo, Sao Paulo, Brazil.
[Ti] Título:Does adaptation to vertebrate codon usage relate to flavivirus emergence potential?
[So] Source:PLoS One;13(1):e0191652, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Codon adaptation index (CAI) is a measure of synonymous codon usage biases given a usage reference. Through mutation, selection, and drift, viruses can optimize their replication efficiency and produce more offspring, which could increase the chance of secondary transmission. To evaluate how higher CAI towards the host has been associated with higher viral titers, we explored temporal trends of several historic and extensively sequenced zoonotic flaviviruses and relationships within the genus itself. To showcase evolutionary and epidemiological relationships associated with silent, adaptive synonymous changes of viruses, we used codon usage tables from human housekeeping and antiviral immune genes, as well as tables from arthropod vectors and vertebrate species involved in the flavivirus maintenance cycle. We argue that temporal trends of CAI changes could lead to a better understanding of zoonotic emergences, evolutionary dynamics, and host adaptation. CAI appears to help illustrate historically relevant trends of well-characterized viruses, in different viral species and genetic diversity within a single species. CAI can be a useful tool together with in vivo and in vitro kinetics, phylodynamics, and additional functional genomics studies to better understand species trafficking and viral emergence in a new host.
[Mh] Termos MeSH primário: Códon/genética
Flavivirus/genética
Flavivirus/patogenicidade
[Mh] Termos MeSH secundário: Adaptação Fisiológica
Aedes/genética
Aedes/virologia
Animais
Culex/genética
Culex/virologia
Vírus da Dengue/genética
Vírus da Dengue/patogenicidade
Vírus da Dengue/fisiologia
Evolução Molecular
Flavivirus/fisiologia
Genes Essenciais
Genoma Viral
Interações Hospedeiro-Patógeno/genética
Seres Humanos
Mosquitos Vetores/genética
Mosquitos Vetores/virologia
Filogenia
Vírus do Mosaico do Tabaco/genética
Vírus do Mosaico do Tabaco/patogenicidade
Vírus do Mosaico do Tabaco/fisiologia
Vertebrados/genética
Vertebrados/virologia
Vírus do Nilo Ocidental/genética
Vírus do Nilo Ocidental/patogenicidade
Vírus do Nilo Ocidental/fisiologia
Vírus da Febre Amarela/genética
Vírus da Febre Amarela/patogenicidade
Vírus da Febre Amarela/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Codon)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180302
[Lr] Data última revisão:
180302
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191652


  3 / 19723 MEDLINE  
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[PMID]:28448468
[Au] Autor:Williams E; Place A; Bachvaroff T
[Ad] Endereço:Institute of Marine and Environmental Technology, University of Maryland Center for Environmental Science, 701 East Pratt St., Baltimore, MD 21202, USA. williamse@umces.edu.
[Ti] Título:Transcriptome Analysis of Core Dinoflagellates Reveals a Universal Bias towards "GC" Rich Codons.
[So] Source:Mar Drugs;15(5), 2017 Apr 27.
[Is] ISSN:1660-3397
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Although dinoflagellates are a potential source of pharmaceuticals and natural products, the mechanisms for regulating and producing these compounds are largely unknown because of extensive post-transcriptional control of gene expression. One well-documented mechanism for controlling gene expression during translation is codon bias, whereby specific codons slow or even terminate protein synthesis. Approximately 10,000 annotatable genes from fifteen "core" dinoflagellate transcriptomes along a range of overall guanine and cytosine (GC) content were used for codonW analysis to determine the relative synonymous codon usage (RSCU) and the GC content at each codon position. GC bias in the analyzed dataset and at the third codon position varied from 51% and 54% to 66% and 88%, respectively. Codons poor in GC were observed to be universally absent, but bias was most pronounced for codons ending in uracil followed by adenine (UA). GC bias at the third codon position was able to explain low abundance codons as well as the low effective number of codons. Thus, we propose that a bias towards codons rich in GC bases is a universal feature of core dinoflagellates, possibly relating to their unique chromosome structure, and not likely a major mechanism for controlling gene expression.
[Mh] Termos MeSH primário: Composição de Bases/genética
Códon/genética
Dinoflagelados/genética
Sequência Rica em GC/genética
Transcriptoma/genética
[Mh] Termos MeSH secundário: Viés
Perfilação da Expressão Gênica/métodos
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170428
[St] Status:MEDLINE


  4 / 19723 MEDLINE  
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[PMID]:28966124
[Au] Autor:Gan HM; Tan MH; Lee YP; Schultz MB; Horwitz P; Burnham Q; Austin CM
[Ad] Endereço:Centre for Integrative Ecology, School of Life and Environmental Sciences, Deakin University, Geelong, Victoria 3220, Australia; Genomics Facility, Tropical and Medicine Biology Platform, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500 Petaling Jaya, Selangor, Malaysia; School
[Ti] Título:More evolution underground: Accelerated mitochondrial substitution rate in Australian burrowing freshwater crayfishes (Decapoda: Parastacidae).
[So] Source:Mol Phylogenet Evol;118:88-98, 2018 Jan.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:To further understand the evolutionary history and mitogenomic features of Australia's highly distinctive freshwater crayfish fauna, we utilized a recently described rapid mitogenome sequencing pipeline to generate 24 new crayfish mitogenomes including a diversity of burrowing crayfish species and the first for Astacopsis gouldi, the world's largest freshwater invertebrate. Whole mitogenome-based phylogeny estimates using both Bayesian and Maximum Likelihood methods substantially strengthen existing hypotheses for systematic relationships among Australian freshwater crayfish with evidence of pervasive diversifying selection and accelerated mitochondrial substitution rate among the members of the clade representing strongly burrowing crayfish that may reflect selection pressures for increased energy requirement for adaptation to terrestrial environment and a burrowing lifestyle. Further, gene rearrangements are prevalent in the burrowing crayfish mitogenomes involving both tRNA and protein coding genes. In addition, duplicated control regions were observed in two closely related Engaeus species, together with evidence for concerted evolution. This study significantly adds to the understanding of Australian freshwater crayfish evolutionary relationships and suggests a link between mitogenome evolution and adaptation to terrestrial environments and a burrowing lifestyle in freshwater crayfish.
[Mh] Termos MeSH primário: Astacoidea/classificação
DNA Mitocondrial/genética
Evolução Molecular
[Mh] Termos MeSH secundário: Animais
Astacoidea/genética
Austrália
Teorema de Bayes
Códon
DNA/química
DNA/isolamento & purificação
DNA/metabolismo
DNA Mitocondrial/química
DNA Mitocondrial/classificação
DNA Mitocondrial/metabolismo
Água Doce
Ordem dos Genes
Funções Verossimilhança
Filogenia
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon); 0 (DNA, Mitochondrial); 9007-49-2 (DNA)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171003
[St] Status:MEDLINE


  5 / 19723 MEDLINE  
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[PMID]:29038046
[Au] Autor:Sun S; Li Q; Kong L; Yu H
[Ad] Endereço:Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China.
[Ti] Título:Multiple reversals of strand asymmetry in molluscs mitochondrial genomes, and consequences for phylogenetic inferences.
[So] Source:Mol Phylogenet Evol;118:222-231, 2018 Jan.
[Is] ISSN:1095-9513
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Strand asymmetry in nucleotide composition is a remarkable feature of animal mitochondrial genomes. The strand-specific bias in the nucleotide composition of the mtDNA has been known to be highly problematic for phylogenetic analyses. Here, the strand asymmetry was compared across 140 mollusc species and analyzed for a mtDNA fragment including twelve protein-coding genes. The analyses show that almost all species in Gastropoda (except Heterobranchia) and all species in Bivalvia present reversals of strand bias. The skew values on individual genes for all codon positions (P ), third codon positions (P ), and fourfold redundant third codon positions (P ) indicated that CG skews are the best indicators of strand asymmetry. The differences in the patterns of strand asymmetry significantly influenced the amino acid composition of the encoded proteins. These biases are most striking for the amino acids Valine, Cysteine, Asparagine and Threonines, which appear to have evolved asymmetrical exchanges in response to shifts in nucleotide composition. Molluscs with strong variability of genome architectures (ARs) are usually characterized by a reversal of the usual strand bias. Phylogenetic analyses show that reversals of asymmetric mutational constraints have consequences on the phylogenetic inferences, as taxa characterized by reverse strand bias (Heterobranchia and Bivalvia) tend to group together due to long-branch attraction (LBA) artifacts. Neutral Transitions Excluded (NTE) model did not overcome the problem of heterogeneous biases present in molluscs mt genomes, suggested it may not be appropriate for molluscs mt genome data. Further refinement phylogenetic models may help us better understand internal relationships among these diverse organisms.
[Mh] Termos MeSH primário: Genoma Mitocondrial
Moluscos/classificação
[Mh] Termos MeSH secundário: Aminoácidos/química
Aminoácidos/metabolismo
Animais
Composição de Bases
Bivalves/classificação
Bivalves/genética
Códon
Gastrópodes/classificação
Gastrópodes/genética
Moluscos/genética
Filogenia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Amino Acids); 0 (Codon)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171018
[St] Status:MEDLINE


  6 / 19723 MEDLINE  
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[PMID]:29342181
[Au] Autor:Tanida-Miyake E; Koike M; Uchiyama Y; Tanida I
[Ad] Endereço:Department of Cell Biology and Neuroscience, Juntendo University School of Medicine, Tokyo, Japan.
[Ti] Título:Optimization of mNeonGreen for Homo sapiens increases its fluorescent intensity in mammalian cells.
[So] Source:PLoS One;13(1):e0191108, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Green fluorescent protein (GFP) is tremendously useful for investigating many cellular and intracellular events. The monomeric GFP mNeonGreen is about 3- to 5-times brighter than GFP and monomeric enhanced GFP and shows high photostability. The maturation half-time of mNeonGreen is about 3-fold faster than that of monomeric enhanced GFP. However, the cDNA sequence encoding mNeonGreen contains some codons that are rarely used in Homo sapiens. For better expression of mNeonGreen in human cells, we synthesized a human-optimized cDNA encoding mNeonGreen and generated an expression plasmid for humanized mNeonGreen under the control of the cytomegalovirus promoter. The resultant plasmid was introduced into HEK293 cells. The fluorescent intensity of humanized mNeonGreen was about 1.4-fold higher than that of the original mNeonGreen. The humanized mNeonGreen with a mitochondria-targeting signal showed mitochondrial distribution of mNeonGreen. We further generated an expression vector of humanized mNeonGreen with 3xFLAG tags at its carboxyl terminus as these tags are useful for immunological analyses. The 3xFLAG-tagged mNeonGreen was recognized well with an anti-FLAG-M2 antibody. These plasmids for the expression of humanized mNeonGreen and mNeonGreen-3xFLAG are useful tools for biological studies in mammalian cells using mNeonGreen.
[Mh] Termos MeSH primário: Corantes/metabolismo
Proteínas de Fluorescência Verde/metabolismo
[Mh] Termos MeSH secundário: Animais
Células COS
Cercopithecus aethiops
Códon
DNA/biossíntese
Células HEK293
Seres Humanos
Mitocôndrias/metabolismo
Plasmídeos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Codon); 0 (Coloring Agents); 147336-22-9 (Green Fluorescent Proteins); 9007-49-2 (DNA)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180118
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0191108


  7 / 19723 MEDLINE  
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[PMID]:29323855
[Au] Autor:Lebedev AV; Kazennova EV; Zverev SY; Nistratova YI; Laga VY; Tumanov AS; Glushchenko NV; Yarygina EI; Bobkova MR
[Ti] Título:Analysis of the env gene variability of the IDU-A HIV-1 variant in the outbreak of the HIV infection epidemic in Perm region of Russia (1996-2011).
[So] Source:Vopr Virusol;61(5):222-9, 2016.
[Is] ISSN:0507-4088
[Cp] País de publicação:Russia (Federation)
[La] Idioma:eng
[Ab] Resumo:In the present work, a total of 132 HIV-1 env gene C2-V3-C3 sequences belonging to the IDU-A genetic variant were analyzed. The variants were obtained from the viruses circulating among IDUs and heterosexuals in the Perm region at different periods. It was shown that the rate of the divergence of the IDU-A HIV-1 viruses from a common ancestor increased 4.3 times (p < 0.001) in 2011 as compared with the onset of the epidemics. The rate of the HIV-1 evolution was different in the two risk groups of the infection. The mean genetic distance of HIV-1 variants circulating among heterosexuals was 1.3 times longer (p = 0.008) than that among IDUs. The accumulation rate of the nucleotide (including nonsynonymous) substitutions in the C2-V3-C3 HIV-1 env gene region among individuals infected by heterosexual contacts was 1.7 times higher than that among IDUs. The differences in the positions of the codons subjected to positive selection were demonstrated depending on the infection risk group tested.
[Mh] Termos MeSH primário: Surtos de Doenças
Variação Genética
Infecções por HIV/epidemiologia
HIV-1/genética
Abuso de Substâncias por Via Intravenosa/epidemiologia
Produtos do Gene env do Vírus da Imunodeficiência Humana/genética
[Mh] Termos MeSH secundário: Adulto
Códon
Feminino
Expressão Gênica
Infecções por HIV/transmissão
Infecções por HIV/virologia
HIV-1/classificação
Heterossexualidade
Seres Humanos
Masculino
Taxa de Mutação
Filogenia
Federação Russa/epidemiologia
Seleção Genética
Abuso de Substâncias por Via Intravenosa/virologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon); 0 (env Gene Products, Human Immunodeficiency Virus)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180112
[St] Status:MEDLINE


  8 / 19723 MEDLINE  
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[PMID]:29229516
[Au] Autor:Halder B; Malakar AK; Chakraborty S
[Ad] Endereço:Department of Biotechnology, Assam University, Silchar 788011, Assam, India.
[Ti] Título:Dissimilar substitution rates between two strands of DNA influence codon usage pattern in some human genes.
[So] Source:Gene;645:179-187, 2018 Mar 01.
[Is] ISSN:1879-0038
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:We illustrated the descriptive aspects of codon usage of some important human genes and their expression potential in E. coli. By comparing the results of various codon usage parameters, effects that are due to selection and mutational pressures have been deciphered. The variation in GC3s explains a significant proportion of the variation in codon usage patterns. The codons CGC, CGG, CTG and GCG showed strong positive correlation with GC3, which suggested that codon usage had been influenced by GC bias. We also found that ACC (Thr, RSCU-1.77), GCC (Ala, RSCU-1.67), CCC (Pro, RSCU-1.54), TCC (Ser, RSCU-1.47) were frequently used which signified that C was common at 2nd and 3rd codon positions. Correspondence analysis revealed that F1 axis had significant correlation with various GC contents suggesting that compositional properties under mutation pressure might affect codon usage bias. Nc-GC3 plot analysis suggested that both mutation pressure and natural selection might affect the codon usage bias which is also supported by neutrality plot analysis. The dinucleotide CT, TG and AG were significantly over-represented and CG, TA, AT, TT, and GT were underrepresented due to high rate of spontaneous mutation resulting from cytosine deamination.
[Mh] Termos MeSH primário: Substituição de Aminoácidos
DNA/genética
[Mh] Termos MeSH secundário: Composição de Bases
Códon
Biologia Computacional/métodos
Evolução Molecular
Seres Humanos
Taxa de Mutação
Seleção Genética
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon); 9007-49-2 (DNA)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180129
[Lr] Data última revisão:
180129
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171213
[St] Status:MEDLINE


  9 / 19723 MEDLINE  
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[PMID]:27775231
[Au] Autor:Wang SX; Xu YP
[Ad] Endereço:Key Laboratory of Shenzhen for Histocompatibility and Immunogenetics, Shenzhen Blood Center, Shenzhen, P. R. China.
[Ti] Título:Genomic full-length sequence of two HLA-A alleles, A*24:08 and A*24:10, identified by cloning and sequencing.
[So] Source:HLA;88(6):300-302, 2016 12.
[Is] ISSN:2059-2310
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Genomic full-length sequences of HLA-A*24:08 and A*24:10, were identified by cloning and sequencing.
[Mh] Termos MeSH primário: Alelos
Éxons
Antígeno HLA-A24/genética
Polimorfismo de Nucleotídeo Único
Doadores de Tecidos
Regiões não Traduzidas
[Mh] Termos MeSH secundário: Sequência de Bases
Clonagem Molecular
Códon/química
Expressão Gênica
Genótipo
Antígeno HLA-A24/imunologia
Transplante de Células-Tronco Hematopoéticas
Teste de Histocompatibilidade
Seres Humanos
Íntrons
Reação em Cadeia da Polimerase
Alinhamento de Sequência
Análise de Sequência de DNA
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Codon); 0 (HLA-A24 Antigen); 0 (Untranslated Regions)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180127
[Lr] Data última revisão:
180127
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161025
[St] Status:MEDLINE
[do] DOI:10.1111/tan.12916


  10 / 19723 MEDLINE  
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[PMID]:29199828
[Au] Autor:Sun X; Xue X; Li M; Gao F; Hao Z; Huang H; Luo H; Qin L; Yao B; Su X
[Ad] Endereço:Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences , Beijing 100081, China.
[Ti] Título:Efficient Coproduction of Mannanase and Cellulase by the Transformation of a Codon-Optimized Endomannanase Gene from Aspergillus niger into Trichoderma reesei.
[So] Source:J Agric Food Chem;65(50):11046-11053, 2017 Dec 20.
[Is] ISSN:1520-5118
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cellulase and mannanase are both important enzyme additives in animal feeds. Expressing the two enzymes simultaneously within one microbial host could potentially lead to cost reductions in the feeding of animals. For this purpose, we codon-optimized the Aspergillus niger Man5A gene to the codon-usage bias of Trichoderma reesei. By comparing the free energies and the local structures of the nucleotide sequences, one optimized sequence was finally selected and transformed into the T. reesei pyridine-auxotrophic strain TU-6. The codon-optimized gene was expressed to a higher level than the original one. Further expressing the codon-optimized gene in a mutated T. reesei strain through fed-batch cultivation resulted in coproduction of cellulase and mannanase up to 1376 U·mL and 1204 U·mL , respectively.
[Mh] Termos MeSH primário: Aspergillus niger/enzimologia
Celulase/genética
Códon/genética
Proteínas Fúngicas/genética
Trichoderma/genética
beta-Manosidase/genética
[Mh] Termos MeSH secundário: Aspergillus niger/genética
Celulase/química
Celulase/metabolismo
Celulose/metabolismo
Códon/metabolismo
Proteínas Fúngicas/metabolismo
Cinética
Engenharia de Proteínas
Trichoderma/metabolismo
beta-Manosidase/química
beta-Manosidase/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Codon); 0 (Fungal Proteins); 9004-34-6 (Cellulose); EC 3.2.1.25 (beta-Mannosidase); EC 3.2.1.4 (Cellulase)
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180110
[Lr] Data última revisão:
180110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171205
[St] Status:MEDLINE
[do] DOI:10.1021/acs.jafc.7b05114



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