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[PMID]:28683004
[Au] Autor:Ryder M; Duley C
[Ad] Endereço:Ryder Science, Inc, Brentwood, Tennessee (Dr Ryder); and BioScience Laboratories, Inc, Bozeman, Montana (Ms Duley). Marcia Ryder, PhD, MS, RN, of Ryder Science, is an independent collaborative researcher and consultant in medical biofilm-related infections. Her nursing practice includes critical care and nutrition support. She is a nationally and internationally recognized expert in the use and management of vascular access devices. Collette Duley, BS, has worked in the clinical laboratory for BioScience Laboratories for 10 years and as a principal investigator for more than 6 years. She has been an author on manuscripts and posters for various studies at numerous conferences.
[Ti] Título:Evaluation of Compatibility of a Gum Mastic Liquid Adhesive and Liquid Adhesive Remover With an Alcoholic Chlorhexidine Gluconate Skin Preparation.
[So] Source:J Infus Nurs;40(4):245-252, 2017 Jul/Aug.
[Is] ISSN:1539-0667
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The compatibility of a 2% chlorhexidine gluconate/70% isopropyl alcohol (CHG/IPA) skin preparation with a gum mastic liquid adhesive (GMLA) and liquid adhesive remover (LAR) was assessed in healthy volunteers. Twenty subjects completed test material combination with microbial sampling at 3- and 7-day time points. Mean log10 reductions from baseline for normal flora were assessed. There was no significant difference in reduction of normal flora on skin prepped with CHG/IPA versus skin prepped with CHG/IPA followed by GMLA or LAR. The conclusion of the study was that the use of GMLA or LAR with CHG/IPA does not affect the antiseptic effectiveness of CHG/IPA.
[Mh] Termos MeSH primário: Adesivos
Antibacterianos/farmacologia
Clorexidina/análogos & derivados
Resina Mástique
Pele/microbiologia
[Mh] Termos MeSH secundário: Adesivos/farmacologia
Bandagens/microbiologia
Clorexidina/farmacologia
Contagem de Colônia Microbiana/métodos
Voluntários Saudáveis
Seres Humanos
Controle de Infecções
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Adhesives); 0 (Anti-Bacterial Agents); 0 (Mastic Resin); MOR84MUD8E (chlorhexidine gluconate); R4KO0DY52L (Chlorhexidine)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170912
[Lr] Data última revisão:
170912
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE
[do] DOI:10.1097/NAN.0000000000000230


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[PMID]:28151818
[Au] Autor:Auyong DB; Cantor DA; Green C; Hanson NA
[Ad] Endereço:From the *Department of Anesthesiology, Virginia Mason Medical Center, Seattle, Washington; and †Duke University School of Medicine, Department of Biostatistics and Bioinformatics, Durham, North Carolina.
[Ti] Título:The Effect of Fixation Technique on Continuous Interscalene Nerve Block Catheter Success: A Randomized, Double-Blind Trial.
[So] Source:Anesth Analg;124(3):959-965, 2017 Mar.
[Is] ISSN:1526-7598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Continuous peripheral nerve blocks offer advantages over single-injection blocks, including extended analgesia and reduction in opioid consumption. These benefits require that the perineural catheter remain intact for the duration of the planned local anesthetic infusion. Mechanical displacement of catheters, leaking, and consequent failure are known complications. The aim of this study was to evaluate continuous perineural catheter tip-to-nerve apposition in vivo over 48 hours comparing 2 different simple fixation strategies. METHODS: Subjects presenting for a continuous interscalene nerve block were randomized to perineural catheter fixation with 1 of 2 types of adhesive: Dermabond (2-octylcyanoacrylate) or Mastisol (alcohol 23A, gum mastic, storax, and methyl salicylate), covered with a simple transparent dressing. The primary outcome was the evaluation of catheter-to-nerve apposition maintenance over 48 hours via both a blinded ultrasound evaluation of local anesthetic distribution and a blinded clinical assessment. Secondary outcomes included leakage at the catheter site, pain scores, opioid consumption, catheter-to-skin migration at the insertion site, and patient satisfaction. RESULTS: Sixty-six subjects were recruited and randomized to compare adhesive group catheter tip-to-nerve apposition on postoperative day 2 (POD 2). Within the intention-to-treat cohort, a statistically significant decrease of perineural catheter tip-to-nerve apposition in the Mastisol group (64.7%) compared with the Dermabond group (90.6%) on POD 2 (odds ratios [OR] 0.19; 95% confidence interval [CI] 0.05-0.75; P = .012) was observed. Similar results were observed on POD 1 (OR 0.19; 95% CI 0.03-1.38; P = NS) and POD 2 (OR 0.14; 95% CI 0.02-0.97; P = .008) within the as-treated cohort. Catheter leakage (OR 67; 95% CI 7.3-589) and median catheter migration difference at the skin insertion site (2.0 cm; 95% CI 0.5-2.5) were also significantly greater in the Mastisol group than in the Dermabond group from POD 0 to POD 2 (P < .001). Median postoperative opioid consumption difference in morphine equivalents (3.2 mg; 95% CI - 9.0 to 14.2) was not significantly different between the Dermabond and the Mastisol groups through POD 2 (P = .542). CONCLUSIONS: Perineural catheter fixation with Dermabond in continuous interscalene nerve block improves maintenance of catheter-to-nerve apposition when compared with Mastisol.
[Mh] Termos MeSH primário: Bloqueio Nervoso Autônomo/instrumentação
Bloqueio Nervoso Autônomo/métodos
Cateteres de Demora
Cianoacrilatos/administração & dosagem
Resina Mástique/administração & dosagem
Adesivos Teciduais/administração & dosagem
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Método Duplo-Cego
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Cyanoacrylates); 0 (Mastic Resin); 0 (Tissue Adhesives); 6C655P1XVG (octyl 2-cyanoacrylate)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170714
[Lr] Data última revisão:
170714
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170203
[St] Status:MEDLINE
[do] DOI:10.1213/ANE.0000000000001811


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[PMID]:27858280
[Au] Autor:Jin Y; Zhao J; Jeong KM; Yoo DE; Han SY; Choi SY; Ko DH; Kim HJ; Sung NH; Lee J
[Ad] Endereço:School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi, 16419, Republic of Korea.
[Ti] Título:A simple and reliable analytical method based on HPLC-UV to determine oleanonic acid content in Chios gum mastic for quality control.
[So] Source:Arch Pharm Res;40(1):49-56, 2017 Jan.
[Is] ISSN:0253-6269
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:A reliable analytical method based on high-performance liquid chromatography-ultraviolet detection was established for the determination of oleanonic acid (OA) content in Chios gum mastic (CGM). A simple method involving methanol extraction of CGM powder followed by basification and ether extraction was developed to isolate the triterpenic fraction including OA. The triterpenic fraction was chromatographed on a Phenomenex Gemini C column (150 × 4.6 mm, 5 µm) under a simple gradient elution of a mobile phase containing acetonitrile and water at a flow rate of 1.0 mL min . The detection wavelength was set at 210 nm. Good linearity was achieved in the range of 100.0-1000.0 µg mL with r > 0.9993, and the limit of quantification was 32.22 µg mL . Accuracy measured at three concentration levels was in the range of 93.72-99.56%, while intra-day and inter-day precisions estimated using both OA standard and CGM samples were no more than 2.83 and 4.57% RSD, respectively. Finally, this method was applied to real CGM samples from various batches, revealing that the OA contents were between 88.13 and 100.83 µg mg . These results suggest that the current method can be applied as an efficient analytical method for quality control of CGM.
[Mh] Termos MeSH primário: Química Farmacêutica/métodos
Química Farmacêutica/normas
Resina Mástique/análise
Controle de Qualidade
Triterpenos/análise
[Mh] Termos MeSH secundário: Cromatografia Líquida de Alta Pressão/métodos
Cromatografia Líquida de Alta Pressão/normas
Resina Mástique/química
Reprodutibilidade dos Testes
Triterpenos/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Mastic Resin); 0 (Triterpenes); 0 (oleanonic acid)
[Em] Mês de entrada:1702
[Cu] Atualização por classe:170201
[Lr] Data última revisão:
170201
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161119
[St] Status:MEDLINE
[do] DOI:10.1007/s12272-016-0853-2


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[PMID]:27514656
[Au] Autor:Paraschos S; Magiatis P; Gikas E; Smyrnioudis I; Skaltsounis AL
[Ad] Endereço:Laboratory of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, University of Athens, Panepistimiopolis Zografou, GR 15771 Athens, Greece.
[Ti] Título:Quality profile determination of Chios mastic gum essential oil and detection of adulteration in mastic oil products with the application of chiral and non-chiral GC-MS analysis.
[So] Source:Fitoterapia;114:12-17, 2016 Oct.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The determination of mastic oil profile, with emphasis on its chiral characteristics, could serve as a method for detecting adulteration in products found in the market with a claim of mastic oil content aiming towards protecting it from counterfeiting. Furthermore the evaluation of the raw material is crucial, as the profile is potentially affected by factors as mastic origin and storage time. Thus 45 authentic mastic oil samples were analyzed by GC-MS employing a chiral column and content limits for all major constituents were determined. The chiral GC-MS analysis proved that selected concentration ratios between these constituents, namely those of (-)/(+)-α-pinene (≤1:100) and (-)-α-pinene/myrcene (1.9:100-11:100) could serve as markers for the determination of mastic oil authenticity. Employing this methodology, the analysis of 25 mastic oils contained in cosmetic and dietary products, as well as an artificial mastic oil sample, exhibited several differentiations that could indicate adulteration either with artificial essential oils or volatile compounds, or the use of aged mastic oil.
[Mh] Termos MeSH primário: Contaminação de Medicamentos
Resina Mástique/análise
Resina Mástique/normas
Óleos Voláteis/análise
Óleos Voláteis/normas
[Mh] Termos MeSH secundário: Alcenos/análise
Goma de Mascar/análise
Cosméticos/análise
Cromatografia Gasosa-Espectrometria de Massas
Monoterpenos/análise
Pistacia/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Alkenes); 0 (Chewing Gum); 0 (Cosmetics); 0 (Mastic Resin); 0 (Monoterpenes); 0 (Oils, Volatile); 3M39CZS25B (myrcene); JPF3YI7O34 (alpha-pinene)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170123
[Lr] Data última revisão:
170123
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160813
[St] Status:MEDLINE


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[PMID]:27316396
[Au] Autor:Andreadou I; Mitakou S; Paraschos S; Efentakis P; Magiatis P; Kaklamanis L; Halabalaki M; Skaltsounis L; Iliodromitis EK
[Ad] Endereço:Department of Pharmaceutical Chemistry, School of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, 15771, Athens, Greece. Electronic address: jandread@pharm.uoa.gr.
[Ti] Título:"Pistacia lentiscus L." reduces the infarct size in normal fed anesthetized rabbits and possess antiatheromatic and hypolipidemic activity in cholesterol fed rabbits.
[So] Source:Phytomedicine;23(11):1220-6, 2016 Oct 15.
[Is] ISSN:1618-095X
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:HYPOTHESIS/PURPOSE: The aim of the present study was to evaluate in vivo the potential anti-ischemic and antiatheromatic activity of Chios Mastic gum, the resin of the trunk and branches of "Pistacia lentiscus var. chia", used since antiquity in traditional Greek medicine. The main compounds of mastic are triterpenes, possessing phytosterol-like structures. This led to the hypothesis that mastic and particularly its neutral fraction, enriched in phytosterol-like compounds, possess antiatheromatic activities. METHODS: Total Mastic Extract without Polymer (TMEWP) and the neutral mastic fraction (NMF) were administered orally for 6 weeks to normal fed and to cholesterol fed rabbits in the form of sunflower oil solution. All the animals were randomly divided into 6 groups, anesthetized and subjected to 30min ischemia of the heart, followed by 3h reperfusion: At the end of the experiment the area at risk and the infarct zone were determined with the aid of fluorescent particles and triphenyl tetrazolium chloride staining, and small segments of the ascending and descending aorta and the heart were taken for histologic examination. Blood samples were collected at different time points of ischemia and reperfusion, for malondialdehyde (MDA) evaluation as an index of lipid peroxidation, for total and LDL cholesterol determination and for evaluation of oxidized LDL. RESULTS: In the normal fed animals the NMF and the TMEWP reduced significantly the infarct size, while in the hypercholesterolemic rabbits both treatments were ineffective. Atherosclerosis was detected in all the animals fed cholesterol enriched diet in the form of subintimal accumulation of lipids and foamy macrophages. There was no detection of atherosclerosis in Groups treated with TMEWP and NMF, which both reduced the total cholesterol levels by 47 and 88% respectively, whilst had not effect on LDL oxidation. TMEWP and NMF reduced the MDA concentration in normal fed rabbits, but had no effect on MDA levels in cholesterol fed animals. TMEWP and NMPF reduce the infarct size in normal animals and possess significant antiatheromatic and hypolipidemic activities in rabbits fed cholesterol enriched diet.
[Mh] Termos MeSH primário: Hipercolesterolemia/tratamento farmacológico
Resina Mástique/uso terapêutico
Isquemia Miocárdica/tratamento farmacológico
Fitosteróis/uso terapêutico
Extratos Vegetais/uso terapêutico
Resinas Vegetais/uso terapêutico
Triterpenos/uso terapêutico
[Mh] Termos MeSH secundário: Ração Animal/efeitos adversos
Animais
Anticolesterolemiantes/farmacologia
Anticolesterolemiantes/uso terapêutico
Grécia
Masculino
Fitosteróis/farmacologia
Pistacia/química
Extratos Vegetais/farmacologia
Coelhos
Resinas Vegetais/farmacologia
Triterpenos/farmacologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anticholesteremic Agents); 0 (Mastic Resin); 0 (Phytosterols); 0 (Plant Extracts); 0 (Resins, Plant); 0 (Triterpenes)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160619
[St] Status:MEDLINE


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[PMID]:26472569
[Au] Autor:Hood CR; Cornell RS; Greenfield B
[Ad] Endereço:Chief Resident, Department of Foot and Ankle Surgery, Crozer Keystone Health System, Chester, PA. Electronic address: crhoodjr12@gmail.com.
[Ti] Título:Liquid Adhesive Contact Dermatitis After Bunionectomy: A Case Report and Literature Review.
[So] Source:J Foot Ankle Surg;55(1):209-14, 2016 Jan-Feb.
[Is] ISSN:1542-2224
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Hypersensitivity reactions to the skin adherents used in postoperative dressings are an uncommon but unfavorable complication that can result in poor wound healing, increased scarring, and surgical wound infections. This unexpected and unforeseen complication is not well documented in the current published data. We present the case of a 39-year-old female who had undergone a bunionectomy procedure and developed allergic contact dermatitis postoperatively. We discuss the clinical findings and treatments administered after application of a commonly used liquid skin adhesive applied intraoperatively. Through the use of topical and oral steroids and foot soaks in astringent solutions, over the course of several months, the patient's skin returned to the expected postoperative appearance. With the increased consciousness to minimize surgical scarring to improve cosmesis, one of these causes of the reaction might have been the liquid adhesive used in the surgical closure and dressing application. Therefore, we additionally reviewed the adhesive compound's chemical makeup and any potential cross-reactivity to help surgeons make an informed decision of whether to use a liquid adhesive. The various ingredients in liquid adhesives contain known allergen compounds that can cause a reaction, such as balsam of Peru and colophony or rosin, both of which are reviewed in our report. We also present a treatment algorithm developed from the compiled data in the case of a patient developing an allergic reaction. From our literature review and considering the percentage of incidence, if a surgeon desires to use a liquid adhesive product, Mastisol(®) should be chosen because of its lower reactivity and greater adhesive properties compared with the compound tincture of benzoin.
[Mh] Termos MeSH primário: Hallux Valgus/cirurgia
Procedimentos Ortopédicos/efeitos adversos
Resinas Vegetais/efeitos adversos
[Mh] Termos MeSH secundário: Adesivos
Adulto
Dermatite Alérgica de Contato/etiologia
Feminino
Seres Humanos
Resina Mástique
Procedimentos Ortopédicos/métodos
Pistacia
Infecção da Ferida Cirúrgica/prevenção & controle
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Adhesives); 0 (Mastic Resin); 0 (Resins, Plant)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:170103
[Lr] Data última revisão:
170103
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151017
[St] Status:MEDLINE


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[PMID]:26311707
[Au] Autor:Kartalis A; Didagelos M; Georgiadis I; Benetos G; Smyrnioudis N; Marmaras H; Voutas P; Zotika C; Garoufalis S; Andrikopoulos G
[Ad] Endereço:Cardiology Department, 'Skylitseio' General Hospital of Chios, Greece thkartal@otenet.gr.
[Ti] Título:Effects of Chios mastic gum on cholesterol and glucose levels of healthy volunteers: A prospective, randomized, placebo-controlled, pilot study (CHIOS-MASTIHA).
[So] Source:Eur J Prev Cardiol;23(7):722-9, 2016 May.
[Is] ISSN:2047-4881
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Chios mastic gum (CMG) possesses anti-oxidant, anti-inflammatory, anti-atheromatic, lipid- and glucose-lowering properties. We evaluated the effects of CMG on cholesterol and fasting plasma glucose (FPG) levels of healthy volunteers. DESIGN: A prospective, randomized, placebo-controlled, pilot study. METHODS: One hundred and seventy nine volunteers with total cholesterol levels >200 mg/dl were randomized to four groups. Finally, 156 volunteers completed the follow-up period and were analysed: (1) control group (C, n = 23), receiving placebo; (2) total mastic (TM, n = 72) receiving daily a total dose of 1 g of crude CMG (330 mg capsules, tid); (3) polymer-free mastic (PFM, n = 33), receiving daily a total dose of 1 g of polymer free mastic (330 mg caps, tid); and (4) powder mastic (PM, n = 28), receiving daily a total dose of 2 g of crude CMG. RESULTS: After eight weeks, the TM group reduced total cholesterol by 11.5 mg/dl (p < 0.05) and FPG by 4.5 mg/dl (p < 0.05) adjusted for age, gender, BMI and baseline characteristics. The effect was stronger in overweight and obese patients (BMI > 25), with an estimated mean reduction of total cholesterol by 13.5 mg/dl (p < 0.05) and FPG by 5.1 mg/dl (p < 0.05). Administration of PFM and PM resulted in no statistically significant alteration. No effect was observed on LDL, HDL, triglycerides, uric acid and CRP. No gastrointestinal, liver or renal adverse events were recorded. CONCLUSIONS: CMG has a significant lowering effect on total cholesterol and glucose levels of healthy volunteers, with excellent tolerance and no detectable side effects, especially in overweight and obese individuals.
[Mh] Termos MeSH primário: Aterosclerose/prevenção & controle
Glicemia/metabolismo
Dislipidemias/sangue
Resina Mástique/administração & dosagem
[Mh] Termos MeSH secundário: Aterosclerose/sangue
Aterosclerose/etiologia
Glicemia/efeitos dos fármacos
Relação Dose-Resposta a Droga
Dislipidemias/complicações
Dislipidemias/tratamento farmacológico
Jejum/sangue
Feminino
Voluntários Saudáveis
Seres Humanos
Lipídeos/sangue
Masculino
Meia-Idade
Projetos Piloto
Estudos Prospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Blood Glucose); 0 (Lipids); 0 (Mastic Resin)
[Em] Mês de entrada:1701
[Cu] Atualização por classe:170111
[Lr] Data última revisão:
170111
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150828
[St] Status:MEDLINE
[do] DOI:10.1177/2047487315603186


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[PMID]:25133901
[Au] Autor:Georgiadis I; Karatzas T; Korou LM; Katsilambros N; Perrea D
[Ad] Endereço:Department of Experimental Surgery and Surgical Research "N.S. Christeas," Athens School of Medicine, University of Athens , Athens, Greece .
[Ti] Título:Beneficial health effects of Chios Gum Mastic and peroxisome proliferator-activated receptors: indications of common mechanisms.
[So] Source:J Med Food;18(1):1-10, 2015 Jan.
[Is] ISSN:1557-7600
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:For thousands of years, Chios Gum Mastic (CGM), the resin produced by the trunk of Pistachia lentiscus var Chia, has been used for culinary and medicinal purposes and several therapeutic properties have been attributed to it. CGM has been used in traditional medicine of various nations in the eastern Mediterranean area. This survey was carried out to identify biological mechanisms that could explain traditional usage and recent pharmacological findings. We reviewed the related scientific literature available from the NCBI PUBMED database on CGM studies and on natural products showing peroxisome proliferator-activated receptor (PPAR) agonist effects. We investigated whether CGM qualifies as a PPAR modulator. A large number of studies demonstrate that CGM has antioxidant, anti-inflammatory, hypolipidemic, and anticancer properties. Recently, the first evidence of CGM antidiabetic effect became known. CGM chemical composition has been extensively analyzed and the presence of several compounds, especially triterpenoids is well documented. Some of them, oleanonic acid, oleanolic acid, and gallic acid are considered to act as PPAR modulators. PPARs are nuclear receptors functioning as transcription factors and thereby controlling cellular functions at the level of gene expression. PPARs are involved in the pathways of significant diseases, such as metabolic syndrome, diabetes mellitus, dyslipidemia, inflammation, atheromatosis, and neoplasias, constituting a key target for pharmacological interventions. This article proposes that the synergistic action of some constituents of CGM on PPARs and more precisely on both PPARs isotypes-α and -γ, may be one of the major biological mechanisms via which CGM exerts its multiple effects.
[Mh] Termos MeSH primário: Receptores Ativados por Proliferador de Peroxissomo/metabolismo
Fitoterapia
Pistacia/química
Extratos Vegetais/farmacologia
Fatores de Transcrição/metabolismo
Triterpenos/farmacologia
[Mh] Termos MeSH secundário: Animais
Anti-Inflamatórios/farmacologia
Anti-Inflamatórios/uso terapêutico
Antineoplásicos Fitogênicos/farmacologia
Antineoplásicos Fitogênicos/uso terapêutico
Seres Humanos
Hipoglicemiantes/farmacologia
Hipoglicemiantes/uso terapêutico
Hipolipemiantes/farmacologia
Hipolipemiantes/uso terapêutico
Resina Mástique
Extratos Vegetais/uso terapêutico
Resinas Vegetais/química
Resinas Vegetais/farmacologia
Resinas Vegetais/uso terapêutico
Triterpenos/uso terapêutico
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Antineoplastic Agents, Phytogenic); 0 (Hypoglycemic Agents); 0 (Hypolipidemic Agents); 0 (Mastic Resin); 0 (Peroxisome Proliferator-Activated Receptors); 0 (Plant Extracts); 0 (Resins, Plant); 0 (Transcription Factors); 0 (Triterpenes)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140819
[St] Status:MEDLINE
[do] DOI:10.1089/jmf.2014.0021


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[PMID]:25409047
[Au] Autor:Yilmaz B; Altinbas A; Ekiz F; Aktas B
[Ad] Endereço:Diskapi Yildirim Beyazit Education and Research Hospital, Gastroenterology, Ankara, Turkey.
[Ti] Título:Successful treatment with pineapple juice of a gastric bezoar caused by mastic.
[So] Source:Endoscopy;46 Suppl 1 UCTN:E519, 2014.
[Is] ISSN:1438-8812
[Cp] País de publicação:Germany
[La] Idioma:eng
[Mh] Termos MeSH primário: Ananas
Bezoares/tratamento farmacológico
Fitoterapia
Preparações de Plantas/uso terapêutico
Estômago
[Mh] Termos MeSH secundário: Bezoares/induzido quimicamente
Endoscopia Gastrointestinal
Seres Humanos
Masculino
Resina Mástique
Meia-Idade
Resinas Vegetais/efeitos adversos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Mastic Resin); 0 (Plant Preparations); 0 (Resins, Plant)
[Em] Mês de entrada:1507
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141120
[St] Status:MEDLINE
[do] DOI:10.1055/s-0034-1377598


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[PMID]:25054150
[Au] Autor:Karygianni L; Cecere M; Skaltsounis AL; Argyropoulou A; Hellwig E; Aligiannis N; Wittmer A; Al-Ahmad A
[Ad] Endereço:Department of Operative Dentistry and Periodontology, Center for Dental Medicine, University of Freiburg, Hugstetter Straße 55, 79106 Freiburg, Germany.
[Ti] Título:High-level antimicrobial efficacy of representative Mediterranean natural plant extracts against oral microorganisms.
[So] Source:Biomed Res Int;2014:839019, 2014.
[Is] ISSN:2314-6141
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Nature is an unexplored reservoir of novel phytopharmaceuticals. Since biofilm-related oral diseases often correlate with antibiotic resistance, plant-derived antimicrobial agents could enhance existing treatment options. Therefore, the rationale of the present report was to examine the antimicrobial impact of Mediterranean natural extracts on oral microorganisms. Five different extracts from Olea europaea, mastic gum, and Inula viscosa were tested against ten bacteria and one Candida albicans strain. The extraction protocols were conducted according to established experimental procedures. Two antimicrobial assays--the minimum inhibitory concentration (MIC) assay and the minimum bactericidal concentration (MBC) assay--were applied. The screened extracts were found to be active against each of the tested microorganisms. O. europaea presented MIC and MBC ranges of 0.07-10.00 mg mL(-1) and 0.60-10.00 mg mL(-1), respectively. The mean MBC values for mastic gum and I. viscosa were 0.07-10.00 mg mL(-1) and 0.15-10.00 mg mL(-1), respectively. Extracts were less effective against C. albicans and exerted bactericidal effects at a concentration range of 0.07-5.00 mg mL(-1) on strict anaerobic bacteria (Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, and Parvimonas micra). Ethyl acetate I. viscosa extract and total mastic extract showed considerable antimicrobial activity against oral microorganisms and could therefore be considered as alternative natural anti-infectious agents.
[Mh] Termos MeSH primário: Anti-Infecciosos/química
Farmacorresistência Bacteriana
Boca/microbiologia
Olea/química
Extratos Vegetais/química
Resinas Vegetais/química
[Mh] Termos MeSH secundário: Biofilmes
Candida/efeitos dos fármacos
Escherichia coli/efeitos dos fármacos
Seres Humanos
Inula/química
Resina Mástique
Região do Mediterrâneo
Testes de Sensibilidade Microbiana
Folhas de Planta/química
Pressão
Staphylococcus aureus/efeitos dos fármacos
Streptococcus/efeitos dos fármacos
Águas Residuais
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Infective Agents); 0 (Mastic Resin); 0 (Plant Extracts); 0 (Resins, Plant); 0 (Waste Water)
[Em] Mês de entrada:1509
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140724
[St] Status:MEDLINE
[do] DOI:10.1155/2014/839019



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