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Pesquisa : D20.215.784.937 [Categoria DeCS]
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[PMID]:28466135
[Au] Autor:da Silveira TFF; Meinhart AD; de Souza TCL; Cunha ECE; de Moraes MR; Filho JT; Godoy HT
[Ad] Endereço:School of Food Engineering, State University of Campinas (UNICAMP), Campinas, SP, Brazil. ferreira.tayse@gmail.com.
[Ti] Título:Optimization of the Preparation Conditions of Yerba Mate tea Beverage to Maximize Chlorogenic Acids Extraction.
[So] Source:Plant Foods Hum Nutr;72(2):219-223, 2017 Jun.
[Is] ISSN:1573-9104
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The beverage obtained from the yerba mate tea, besides being the most consumed in Brazil, has high concentrations of chlorogenic acids. In this study, a central composite design was employed to establish the best infusion time, temperature and water volume to maximize the extraction of chlorogenic acids 5-caffeoylquinic (5CQ), 3.4-dicaffeoylquinic (3.4 DQ), 3.5-dicaffeoylquinic (3.5 DQ) and 4.5-dicaffeoylquinic (4.5 DQ), from the leaves and stems of yerba mate tea (beverage ready for consumption). Analyses were performed by high-performance liquid chromatography and the optimum conditions were obtained through the use of the desirability function of Derringer and Suich. The maximum chlorogenic acids content in the beverage was obtained when the infusion was prepared with 2 g of mate tea, in 300 mL of water at 95 °C, under infusion for 16 min. The optimal conditions were applied for the preparation of beverages from 15 commercial samples of yerba mate tea, and it was observed that the sum of the concentration of the four compounds showed variation of up to 79 times between the average of the samples, which can be attributed to climatic conditions of cultivation of the plant and/or of processing.
[Mh] Termos MeSH primário: Ácido Clorogênico/isolamento & purificação
Ilex paraguariensis/química
Ácido Quínico/análogos & derivados
[Mh] Termos MeSH secundário: Brasil
Ácido Clorogênico/análise
Cromatografia Líquida de Alta Pressão
Metanol
Folhas de Planta/química
Caules de Planta/química
Ácido Quínico/análise
Ácido Quínico/isolamento & purificação
Chás de Ervas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Teas, Herbal); 0 (caffeoylquinic acid); 058C04BGYI (Quinic Acid); 318ADP12RI (Chlorogenic Acid); Y4S76JWI15 (Methanol)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171128
[Lr] Data última revisão:
171128
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1007/s11130-017-0613-6


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[PMID]:28655517
[Au] Autor:Dekant W; Fujii K; Shibata E; Morita O; Shimotoyodome A
[Ad] Endereço:Department of Toxicology, University of Würzburg, Versbacher Strasse 9, 97078 Würzburg, Germany. Electronic address: dekant@toxi.uni-wuerzburg.de.
[Ti] Título:Safety assessment of green tea based beverages and dried green tea extracts as nutritional supplements.
[So] Source:Toxicol Lett;277:104-108, 2017 Aug 05.
[Is] ISSN:1879-3169
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The safety of green tea infusions and green tea extract (GTE)-based products is reviewed regarding catechins. Epigallocatechin 3-gallate (EGCG), the major catechin present in green tea, is suspected of being responsible for liver toxicity reported in humans consuming food supplements. Intake of EGCG with green tea infusions and GTE-based beverages is up to about 450mg EGCG/person/day in Europe and higher in Asia. Consumption of green tea is not associated with liver damage in humans, and green tea infusion and GTE-based beverages are considered safe in the range of historical uses. In animal studies, EGCG's potency for liver effects is highly dependent on conditions of administration. Use of NOAELs from bolus administration to derive a tolerable upper intake level applying the margin of safety concept results in acceptable EGCG-doses lower than those from one cup of green tea. NOAELs from toxicity studies applying EGCG with diet/split of the daily dose are a better point of departure for risk characterization. In clinical intervention studies, liver effects were not observed after intakes below 600mg EGCG/person/day. Thus, a tolerable upper intake level of 300mg EGCG/person/day is proposed for food supplements; this gives a twofold safety margin to clinical studies that did not report liver effects and a margin of safety of 100 to the NOAELs in animal studies with dietary administration of green tea catechins.
[Mh] Termos MeSH primário: Camellia sinensis/química
Catequina/análogos & derivados
Suplementos Nutricionais
Inocuidade dos Alimentos
Extratos Vegetais/análise
Chá/química
Chás de Ervas/análise
[Mh] Termos MeSH secundário: Animais
Camellia sinensis/efeitos adversos
Catequina/efeitos adversos
Catequina/análise
Segurança de Produtos ao Consumidor
Suplementos Nutricionais/efeitos adversos
Análise de Perigos e Pontos Críticos de Controle
Seres Humanos
Nível de Efeito Adverso não Observado
Extratos Vegetais/efeitos adversos
Recomendações Nutricionais
Medição de Risco
Chá/efeitos adversos
Chás de Ervas/efeitos adversos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Tea); 0 (Teas, Herbal); 8R1V1STN48 (Catechin); BQM438CTEL (epigallocatechin gallate)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170807
[Lr] Data última revisão:
170807
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170629
[St] Status:MEDLINE


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[PMID]:28534052
[Au] Autor:Parameswari R; Rao KA; Manigandan P; Vickram AS; Archana A; Sridharan TB
[Ad] Endereço:Department of Industrial Biotechnology, School of Biosciences and Technology, VIT University, Vellore, India.
[Ti] Título:Tea polyphenol-T. arjuna bark as sperm antioxidant extender in infertile smokers.
[So] Source:Cryo Letters;38(2):95-99, 2017 Mar/Apr.
[Is] ISSN:0143-2044
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Antioxidants protect spermatozoa against lipid peroxidation during freezing. OBJECTIVE: The study is designed to elucidate the suitable extender to preserve infertile semen of smokers against ROS damage using natural Tea polyphenol (T. arjuna bark extract). MATERIALS AND METHODS: Forty-two infertile subjects with smoking habit and 28 fertile subjects without smoking habit were considered for the study. Four semen extenders including our naturally derived antioxidant component were prepared and used to preserve semen sample from the study subjects for a period of one month. Standard semen parameters, biochemical and sperm DNA damage marker with inhibition were measured before and after cryopreservation. RESULTS: The motility and morphology of sperm cells were maintained better in E4 extender, and DNA damage is reduced. CONCLUSION: Extender recipe with natural antioxidants (E3 and E4) was found to be apt for infertile semen preservation.
[Mh] Termos MeSH primário: Criopreservação/métodos
Infertilidade Masculina
Polifenóis/farmacologia
Preservação do Sêmen/métodos
Espermatozoides
Terminalia
[Mh] Termos MeSH secundário: Antioxidantes/farmacologia
Crioprotetores/farmacologia
Dano ao DNA/efeitos dos fármacos
Seres Humanos
Infertilidade Masculina/etiologia
Infertilidade Masculina/patologia
Peroxidação de Lipídeos/efeitos dos fármacos
Masculino
Casca de Planta
Fumar/efeitos adversos
Motilidade Espermática/efeitos dos fármacos
Espermatozoides/efeitos dos fármacos
Espermatozoides/patologia
Chás de Ervas
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Cryoprotective Agents); 0 (Polyphenols); 0 (Teas, Herbal)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170524
[St] Status:MEDLINE


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[PMID]:28524107
[Au] Autor:Juranovic Cindric I; Zeiner M; Mihajlov-Konanov D; Stingeder G
[Ad] Endereço:Division of Analytical Chemistry, Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia. ijuranovic@chem.pmf.hr.
[Ti] Título:Inorganic Macro- and Micronutrients in "Superberries" Black Chokeberries (Aronia melanocarpa) and Related Teas.
[So] Source:Int J Environ Res Public Health;14(5), 2017 May 18.
[Is] ISSN:1660-4601
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:Black chokeberries ( ) are considered to be functional food containing high amounts of anthocyanins, phenols, antioxidants, vitamins and minerals. Whereas organic compounds are well studied, there is little research on the mineral composition of the chokeberries. Thus, the presented study is focused on the determination of Al, As, Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Li, Mg, Mn, Mo, Na, Ni, Pb, Se, Sr and Zn in black chokeberry fruits and infusions to study the metals' extractability. The nutrients Ca, K and Mg are present in the fruits (dried matter) at g/kg level, whereas the other elements are present from µg/kg up to mg/kg level. The extraction yields of the metals from the infusion range from 4 (Al, Mn) up to 44% (Na). The toxic elements present do not pose any health risk when berries or infusions are consumed. Concluding, Aronia berries, as well as infusions derived from them, are a good dietary source of essential metals in addition to the organic compounds also contained.
[Mh] Termos MeSH primário: Frutas/química
Metais/análise
Micronutrientes/análise
Photinia
Chás de Ervas/análise
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Metals); 0 (Micronutrients); 0 (Teas, Herbal)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171011
[Lr] Data última revisão:
171011
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170520
[St] Status:MEDLINE


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[PMID]:28379220
[Au] Autor:Akinrinmade O; Omoruyi S; Dietrich D; Ekpo O
[Ad] Endereço:Department of Medical Biosciences, University of the Western Cape, Bellville, South Africa.
[Ti] Título:Long-term consumption of fermented rooibos herbal tea offers neuroprotection against ischemic brain injury in rats.
[So] Source:Acta Neurobiol Exp (Wars);77(1):94-105, 2017.
[Is] ISSN:1689-0035
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Stroke is the second leading cause of death worldwide, affecting about 240 people a day in South Africa and leaving survivors with residual disabilities. At the moment, there is no clinically approved neuroprotective product for stroke but the consumption of plant polyphenols has been suggested to offer some protection against stroke. In this study, we investigated the effects of long-term consumption of fermented rooibos herbal tea (FRHT) on ischemia/reperfusion (I/R)-induced brain injury in adult male Wistar rats. FRHT was administered to the animals ad libitum for 7 weeks prior to the induction of ischemic injury via a 20-minute bilateral occlusion of the common carotid arteries (BCCAO) followed by reperfusion for 24, 96 and 168 hours respectively. Neurobehavioural deficits, brain oedema, blood-brain barrier (BBB) damage, apoptosis, lipid peroxidation and total antioxidant capacity were subsequently evaluated using standard methods. Our results showed that long-term consumption of FRHT by Wistar rats signi icantly reduced brain oedema and neuronal apoptosis, but did not attenuate BBB damage following cerebral ischemia. Analysis of whole-brain homogenates showed significantly reduced lipid peroxidation levels, increased total antioxidant capacity and resulted in improved neurobehavioural outcomes in FRHT-treated rats when compared with untreated animals. Taken together, our results tend to suggest that continuous consumption of FRHT could confer some protection against ischemic brain injury (IBI) and is therefore highly recommended for patients with stroke-predisposing conditions.
[Mh] Termos MeSH primário: Aspalathus/química
Lesões Encefálicas/prevenção & controle
Fármacos Neuroprotetores/uso terapêutico
Chás de Ervas
[Mh] Termos MeSH secundário: Animais
Apoptose/efeitos dos fármacos
Barreira Hematoencefálica/efeitos dos fármacos
Barreira Hematoencefálica/fisiopatologia
Encéfalo/efeitos dos fármacos
Encéfalo/metabolismo
Edema Encefálico/tratamento farmacológico
Edema Encefálico/etiologia
Lesões Encefálicas/etiologia
Doenças das Artérias Carótidas/complicações
Modelos Animais de Doenças
Comportamento Exploratório/efeitos dos fármacos
Recuperação de Fluorescência Após Fotodegradação
Marcação In Situ das Extremidades Cortadas
Peroxidação de Lipídeos/efeitos dos fármacos
Masculino
Capacidade de Absorbância de Radicais de Oxigênio
Extratos Vegetais
Ratos
Ratos Wistar
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Avemar); 0 (Neuroprotective Agents); 0 (Plant Extracts); 0 (Teas, Herbal)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170414
[Lr] Data última revisão:
170414
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170406
[St] Status:MEDLINE


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[PMID]:28363507
[Au] Autor:Mansour A; Celano R; Mencherini T; Picerno P; Piccinelli AL; Foudil-Cherif Y; Csupor D; Rahili G; Yahi N; Nabavi SM; Aquino RP; Rastrelli L
[Ad] Endereço:USTHB, University of Sciences and Technology Houari Boumediene, Faculty of Chemistry, BP 32 El-Alia, Bab-Ezzouar, 16111, Algiers, Algeria.
[Ti] Título:A new cineol derivative, polyphenols and norterpenoids from Saharan myrtle tea (Myrtus nivellei): Isolation, structure determination, quantitative determination and antioxidant activity.
[So] Source:Fitoterapia;119:32-39, 2017 Jun.
[Is] ISSN:1873-6971
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The phytochemical profile of decoction and infusion, obtained from the dried leaves of M. nivellei, consumed as tea in Saharan region, was characterized by UHPLC-PDA-HRMS. Fourteen compounds were characterized and, to confirm the proposed structures a preparative procedure followed by NMR spectroscopy was applied. Compound 3 (2-hydroxy-1,8-cineole disaccharide) was a never reported whereas a bicyclic monoterpenoid glucoside (2), two ionol glucosides (1 and 12), a tri-galloylquinic acid (4), two flavonol glycosides (5 and 9), and a tetra-galloylglucose (7), were reported in Myrtus spp. for the first time. Five flavonol O-glycosides (6, 8, 10-11, and 14) togheter a flavonol (13) were also identified. Quantitative determination of phenolic constituents from decoction and infusion has been performed by HPLC-UV-PDA. The phenolic content was found to be 150.5 and 102.6mg/g in decoction and infusion corresponding to 73.8 and 23.6mg/100mL of a single tea cup, respectively. Myricetin 3-O-ß-d-(6″-galloyl)glucopyranoside (5), isomyricitrin (6) and myricitrin (8) were the compounds present in the highest concentration. The free-radical scavenging activities of teas and isolated compounds was measured by the DPPH assay and compared with the values of other commonly used herbal teas (green and black teas). Decoction displayed higher potency in scavenging free-radicals than the infusion and green and black teas.
[Mh] Termos MeSH primário: Antioxidantes/química
Cicloexanóis/química
Monoterpenos/química
Myrtus/química
Chás de Ervas
[Mh] Termos MeSH secundário: Antioxidantes/isolamento & purificação
Cicloexanóis/isolamento & purificação
Flavonoides/química
Flavonoides/isolamento & purificação
Flavonóis/química
Flavonóis/isolamento & purificação
Glucosídeos/química
Glucosídeos/isolamento & purificação
Glicosídeos/química
Glicosídeos/isolamento & purificação
Estrutura Molecular
Monoterpenos/isolamento & purificação
Polifenóis/química
Polifenóis/isolamento & purificação
Terpenos/química
Terpenos/isolamento & purificação
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Cyclohexanols); 0 (Flavonoids); 0 (Flavonols); 0 (Glucosides); 0 (Glycosides); 0 (Monoterpenes); 0 (Polyphenols); 0 (Teas, Herbal); 0 (Terpenes); 5Z0ZO61WPJ (myricitrin); RV6J6604TK (eucalyptol)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170615
[Lr] Data última revisão:
170615
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170402
[St] Status:MEDLINE


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[PMID]:28256049
[Au] Autor:Oliveira AP; Sá I; Pereira DM; Gonçalves RF; Andrade PB; Valentão P
[Ad] Endereço:REQUIMTE/LAQV, Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, R. Jorge Viterbo Ferreira, no. 228, PT-4050-313, Porto.
[Ti] Título:Exploratory Studies on the in Vitro Anti-inflammatory Potential of Two Herbal Teas (Annona muricata L. and Jasminum grandiflorum L.), and Relation with Their Phenolic Composition.
[So] Source:Chem Biodivers;14(6), 2017 Jun.
[Is] ISSN:1612-1880
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:The need of new anti-inflammatory drugs has led to the search for safer and more potent molecules in distinct sources, such as natural products. This work aimed to explore the anti-inflammatory potential of aqueous extracts from two herbal teas (Annona muricata L. and Jasminum grandiflorum L.) in RAW 264.7 macrophages cells and in cell-free assays. Furthermore, the phenolic composition of both extracts and of their hydrolysates was characterized by HPLC-DAD, in order to establish possible relationships with the biological activity. In a general way, A. muricata displayed a stronger capacity to inhibit nitric oxide (NO) production and the activity of phospholipase A (PLA ), displaying an IC value of 142 µg/ml against this enzyme. A deeper look at phenolic compounds revealed that aglycones had more capacity to inhibit NO and PLA than their corresponding glycosides, quercetin being clearly the most potent one (IC  = 7.47 and 1.36 µm, respectively). In addition, 5-O-caffeoylquinic acid, at 1.56 µm, could also inhibit PLA (ca. 35%). Our findings suggest that the consumption of both herbal teas may be a preventive approach to inflammatory disorders.
[Mh] Termos MeSH primário: Anti-Inflamatórios/isolamento & purificação
Chás de Ervas
[Mh] Termos MeSH secundário: Animais
Annona/química
Anti-Inflamatórios/farmacologia
Sistema Livre de Células/efeitos dos fármacos
Jasminum/química
Camundongos
Óxido Nítrico/antagonistas & inibidores
Fenóis/análise
Fenóis/farmacologia
Inibidores de Fosfolipase A2
Extratos Vegetais
Células RAW 264.7
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anti-Inflammatory Agents); 0 (Phenols); 0 (Phospholipase A2 Inhibitors); 0 (Plant Extracts); 0 (Teas, Herbal); 31C4KY9ESH (Nitric Oxide)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170304
[St] Status:MEDLINE
[do] DOI:10.1002/cbdv.201700002


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[PMID]:28192609
[Au] Autor:Grant J; Ryland D; Isaak CK; Prashar S; Siow YL; Taylor CG; Aliani M
[Ad] Endereço:Dept. of Human Nutritional Sciences, Univ. of Manitoba, Winnipeg, MB, Canada.
[Ti] Título:Effect of Vitamin D Fortification and Saskatoon Berry Syrup Addition on the Flavor Profile, Acceptability, and Antioxidant Properties of Rooibos Tea (Aspalathus linearis).
[So] Source:J Food Sci;82(3):807-817, 2017 Mar.
[Is] ISSN:1750-3841
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The unique characteristics and healthful reputation of caffeine-free rooibos tea (RT) make it an ideal carrier for vitamin D supplementation, and a potential base for the addition of Saskatoon berry syrup (SBS), a natural flavor additive. The objective of this study was to determine the effect of vitamin D fortification and SBS addition on the flavor profile, consumer acceptability, and antioxidant properties of RT. Six formulations (RT, RT with SBS, RT with SBS and vitamin D , RT with vitamin D , green tea [GT], and GT with SBS) were evaluated by 12 trained panelists and 114 consumers. The formulations were also assessed for antioxidant capacity, physical characteristics, and untargeted phytochemical content. Sensory results revealed that the mean intensity values for berry and sweet attributes were significantly higher (P < 0.05) while bitter and astringent attributes were significantly lower when SBS was added to RT samples compared to those without syrup. Acceptability of flavor, aftertaste, and overall acceptability were also significantly higher for the RT with SBS. The addition of SBS to RT significantly increased the antioxidant capacities which may increase the related health benefits of RT. SBS contributed several polyphenols, particularly flavonoids, to the tea. Vitamin D added to RT formulations did not significantly affect the sensory attributes, acceptability, or antioxidant content. For the development of a functional vitamin D fortified iced-tea beverage that can be consumed as part of the daily diet, SBS could be a favorable flavoring additive that may provide additional health benefits.
[Mh] Termos MeSH primário: Antioxidantes/farmacologia
Aspalathus
Colecalciferol/administração & dosagem
Comportamento do Consumidor
Rosaceae/química
Paladar
Chás de Ervas/análise
[Mh] Termos MeSH secundário: Antioxidantes/análise
Flavonoides/análise
Flavonoides/farmacologia
Aromatizantes
Manipulação de Alimentos/métodos
Alimentos Fortificados
Frutas/química
Seres Humanos
Extratos Vegetais/química
Extratos Vegetais/farmacologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antioxidants); 0 (Flavonoids); 0 (Flavoring Agents); 0 (Plant Extracts); 0 (Teas, Herbal); 1C6V77QF41 (Cholecalciferol)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170522
[Lr] Data última revisão:
170522
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170214
[St] Status:MEDLINE
[do] DOI:10.1111/1750-3841.13646


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[PMID]:27915198
[Au] Autor:Fibigr J; Satínský D; Solich P
[Ad] Endereço:The Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Heyrovského 1203, Hradec Králové 500 05, Czechia.
[Ti] Título:A new approach to the rapid separation of isomeric compounds in a Silybum marianum extract using UHPLC core-shell column with F5 stationary phase.
[So] Source:J Pharm Biomed Anal;134:203-213, 2017 Feb 05.
[Is] ISSN:1873-264X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In this paper, a new ultra-high performance liquid chromatography (UHPLC) method using a core-shell column with a pentafluorophenyl stationary phase for separation of seven active compounds of a Silybum marianum extract was developed and validated. Silymarin, an extract of Silybum marianum, is known for its abilities to protect the liver from toxic substances, hepatitis therapy, and anti-tumour activity. Silymarin is currently being widely used in commercial preparations and herbal teas. Separation of seven compounds contained in the Silybum marianum extract (taxifolin, silychristin, silydianin, silybin A, silybin B, isosilybin A, isosilybin B) and other substances occurring in real samples was performed on the Kinetex 1.7µ F5 100A (150×2.1mm), 1.7µm particle size core-shell column, with a mobile phase methanol/100mM phosphate buffer pH 2.0 according to the gradient program. A mobile phase 0.35mLmin flow rate and 50°C temperature was used for the separation. The detection wavelength was set at 288nm. Under optimal chromatographic conditions, good linearity with a correlation coefficient of R >0.999 for all compounds was achieved. The available commercial samples of herbal teas and food supplements were extracted with methanol using an ultrasonic bath. After dilution with water and centrifugation, a 2µL sample of the filtered supernatant was directly injected into the UHPLC system. The use of a pentafluorophenyl stationary phase with methanol as the organic component of the mobile phase showed new ways to effectively separate isomeric compounds in herbal extracts, which could not be done with the conventional C18 stationary phase.
[Mh] Termos MeSH primário: Química Farmacêutica/métodos
Suplementos Nutricionais/análise
Cardo Mariano
Extratos Vegetais/análise
Extratos Vegetais/química
Chás de Ervas/análise
[Mh] Termos MeSH secundário: Química Farmacêutica/normas
Cromatografia Líquida de Alta Pressão/métodos
Cromatografia Líquida de Alta Pressão/normas
Isomerismo
Silimarina/análogos & derivados
Silimarina/análise
Silimarina/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Plant Extracts); 0 (Silymarin); 0 (Teas, Herbal); 4RKY41TBTF (silybin); 7P89L7W179 (silydianin); HHN3Q9H3DK (isosilybin A); LK279ER14X (silychristin)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161205
[St] Status:MEDLINE


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[PMID]:27693951
[Au] Autor:Guzelmeric E; Ristivojevic P; Vovk I; Milojkovic-Opsenica D; Yesilada E
[Ad] Endereço:Yeditepe University, Faculty of Pharmacy, Department of Pharmacognosy and Phytotherapy, Kayisdagi Cad., Atasehir, 34755 Istanbul, Turkey.
[Ti] Título:Quality assessment of marketed chamomile tea products by a validated HPTLC method combined with multivariate analysis.
[So] Source:J Pharm Biomed Anal;132:35-45, 2017 Jan 05.
[Is] ISSN:1873-264X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Chamomile tea composed of dried flower heads of Matricaria recutita L. (Asteraceae) is one of the most popular single ingredient herbal teas. Tea industries, spice shops or public bazaars are mostly supplied chamomile as a raw material via cultivation or through nature-picking. However, one of the drawbacks of nature-picking is adulteration. This could be either due to false authentication of the plant materials by ingenuous pickers or intentional/unintentional substitution with other flowers resembling to chamomile in appearance during harvesting. Therefore, quality control of raw chamomile materials before marketing should be carefully considered not only by quantification of apigenin 7-O-glucoside (active marker) but also by fingerprinting of chemical composition. This work presents both quantification of apigenin 7-O-glucoside and chemical fingerprinting of commercial chamomile tea products obtained from different food stores and spice shops by a validated HPTLC method. In addition, HPTLC profiles of investigated chamomile tea samples were compared with HPLC method stated in the European Pharmacopoeia and it was found that HPTLC method was superior to HPLC method in the field of adulteration confirmation. Therefore, fingerprint profiles performed on the silica gel 60 NH F s HPTLC plates combined with pattern recognition techniques of these marketed products were comparatively evaluated with wild and cultivar chamomile samples and also chamomile-like species from Asteraceae. Consequently, not chamomile tea bags but crude flowers sold on market were found to be adulterated with other plant materials.
[Mh] Termos MeSH primário: Camomila/química
Cromatografia Líquida de Alta Pressão/métodos
Análise de Alimentos/métodos
Chás de Ervas/análise
[Mh] Termos MeSH secundário: Apigenina/química
Asteraceae/química
Flores/química
Géis/química
Processamento de Imagem Assistida por Computador
Matricaria/química
Análise Multivariada
Extratos Vegetais/química
Controle de Qualidade
Dióxido de Silício/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Gels); 0 (Plant Extracts); 0 (Teas, Herbal); 7631-86-9 (Silicon Dioxide); 7OF2S66PCH (apigetrin); 7V515PI7F6 (Apigenin)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161004
[St] Status:MEDLINE



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