Base de dados : MEDLINE
Pesquisa : D25 [Categoria DeCS]
Referências encontradas : 68 [refinar]
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[PMID]:28104510
[Au] Autor:Arancon RA; Balu AM; Romero AA; Ojeda M; Gomez M; Blanco J; Domingo JL; Luque R
[Ad] Endereço:Departamento de Quimica Organica, Universidad de Cordoba, Campus de Rabanales, Edificio Marie Curie, E-14014 Cordoba, Spain.
[Ti] Título:Mechanochemically synthesized Ag-based nanohybrids with unprecedented low toxicity in biomedical applications.
[So] Source:Environ Res;154:204-211, 2017 04.
[Is] ISSN:1096-0953
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:A simple and innovative mechanochemical approach was employed to synthesize Ag-polysaccharide nanohybrid materials that were proved to exhibit remarkable surface properties and structures for biomedical applications. The synthesized Ag nanomaterials possessed an unprecedented low cytotoxicity against human cell lines A549 and SH-SY5Y as compared to similarly reported Ag nanomaterials due to the stability and low release of Ag and high biocompatibility of the nanohybrids.
[Mh] Termos MeSH primário: Materiais Biomédicos e Odontológicos/uso terapêutico
Citotoxinas/toxicidade
Citotoxinas/uso terapêutico
Nanoestruturas/toxicidade
Nanoestruturas/uso terapêutico
Prata/toxicidade
Prata/uso terapêutico
[Mh] Termos MeSH secundário: Células A549
Materiais Biomédicos e Odontológicos/toxicidade
Linhagem Celular Tumoral
Sobrevivência Celular/efeitos dos fármacos
China
Seres Humanos
Prata/química
Propriedades de Superfície
Testes de Toxicidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomedical and Dental Materials); 0 (Cytotoxins); 3M4G523W1G (Silver)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:171119
[Lr] Data última revisão:
171119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE


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[PMID]:26756555
[Au] Autor:Stroh DA; Issa K; Scillia A; Issa S; Festa A; Mont MA
[Ad] Endereço:Department of Orthopedics, Union Memorial Hospital, Baltimore, MD.
[Ti] Título:Total Knee Arthroplasty after Complete Patellectomy: A Review.
[So] Source:J Long Term Eff Med Implants;25(3):163-70, 2015.
[Is] ISSN:1940-4379
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The absence or dysfunction of the knee extensor mechanism accelerates degenerative joint disease and complicates knee arthroplasty. Various treatment strategies have been suggested to improve outcomes in total knee arthroplasties after patellectomy (semi- or constrained components, autograft, allograft, prosthetic reconstruction), but the optimal management of this condition is not known. The purpose of this report is to review the relevant basic biology and biomechanics of the patella and the extensor mechanism, and to review the current literature on the management of complete patellectomy during total knee arthroplasty. Tissue engineered heart valves, BMMSCs, oscillatory shear stress, nicotine, F-actin filaments, cell differentiation, endothelial cells.
[Mh] Termos MeSH primário: Artroplastia do Joelho/métodos
Patela/fisiologia
Patela/cirurgia
[Mh] Termos MeSH secundário: Fenômenos Biomecânicos
Materiais Biomédicos e Odontológicos
Transplante Ósseo
Seres Humanos
Articulação do Joelho/fisiopatologia
Próteses e Implantes
Amplitude de Movimento Articular
Reoperação
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomedical and Dental Materials)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:T
[Da] Data de entrada para processamento:160113
[St] Status:MEDLINE


  3 / 68 MEDLINE  
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[PMID]:26067982
[Au] Autor:Bernhardt A; Wehrl M; Paul B; Hochmuth T; Schumacher M; Schütz K; Gelinsky M
[Ad] Endereço:Centre for Translational Bone, Joint and Soft Tissue Research, Medizinische Fakultät, Technische Universität Dresden, Dresden, Germany.
[Ti] Título:Improved Sterilization of Sensitive Biomaterials with Supercritical Carbon Dioxide at Low Temperature.
[So] Source:PLoS One;10(6):e0129205, 2015.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The development of bio-resorbable implant materials is rapidly going on. Sterilization of those materials is inevitable to assure the hygienic requirements for critical medical devices according to the medical device directive (MDD, 93/42/EG). Biopolymer-containing biomaterials are often highly sensitive towards classical sterilization procedures like steam, ethylene oxide treatment or gamma irradiation. Supercritical CO2 (scCO2) treatment is a promising strategy for the terminal sterilization of sensitive biomaterials at low temperature. In combination with low amounts of additives scCO2 treatment effectively inactivates microorganisms including bacterial spores. We established a scCO2 sterilization procedure under addition of 0.25% water, 0.15% hydrogen peroxide and 0.5% acetic anhydride. The procedure was successfully tested for the inactivation of a wide panel of microorganisms including endospores of different bacterial species, vegetative cells of gram positive and negative bacteria including mycobacteria, fungi including yeast, and bacteriophages. For robust testing of the sterilization effect with regard to later application of implant materials sterilization all microorganisms were embedded in alginate/agarose cylinders that were used as Process Challenge Devices (PCD). These PCD served as surrogate models for bioresorbable 3D scaffolds. Furthermore, the impact of scCO2 sterilization on mechanical properties of polysaccharide-based hydrogels and collagen-based scaffolds was analyzed. The procedure was shown to be less compromising on mechanical and rheological properties compared to established low-temperature sterilization methods like gamma irradiation and ethylene oxide exposure as well as conventional steam sterilization. Cytocompatibility of alginate gels and scaffolds from mineralized collagen was compared after sterilization with ethylene oxide, gamma irradiation, steam sterilization and scCO2 treatment. Human mesenchymal stem cell viability and proliferation were not compromised by scCO2 treatment of these materials and scaffolds. We conclude that scCO2 sterilization under addition of water, hydrogen peroxide and acetic anhydride is a very effective, gentle, non-cytotoxic and thus a promising alternative sterilization method especially for biomaterials.
[Mh] Termos MeSH primário: Materiais Biomédicos e Odontológicos
Esterilização/métodos
[Mh] Termos MeSH secundário: Dióxido de Carbono
Temperatura Baixa
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomedical and Dental Materials); 142M471B3J (Carbon Dioxide)
[Em] Mês de entrada:1604
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150613
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0129205


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[PMID]:25615736
[Au] Autor:Tapetado Moraleda A; Sánchez Montero D; Webb DJ; Vázquez García C
[Ad] Endereço:Universidad Carlos III de Madrid, Displays and Photonics Applications Group, Electronics Technology Department, Avda Universidad 30, Leganés 28911, Spain. atapetad@ing.uc3m.es.
[Ti] Título:A self-referenced optical intensity sensor network using POFBGs for biomedical applications.
[So] Source:Sensors (Basel);14(12):24029-45, 2014 Dec 12.
[Is] ISSN:1424-8220
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:This work bridges the gap between the remote interrogation of multiple optical sensors and the advantages of using inherently biocompatible low-cost polymer optical fiber (POF)-based photonic sensing. A novel hybrid sensor network combining both silica fiber Bragg gratings (FBG) and polymer FBGs (POFBG) is analyzed. The topology is compatible with WDM networks so multiple remote sensors can be addressed providing high scalability. A central monitoring unit with virtual data processing is implemented, which could be remotely located up to units of km away. The feasibility of the proposed solution for potential medical environments and biomedical applications is shown.
[Mh] Termos MeSH primário: Técnicas Biossensoriais/métodos
Fibras Ópticas
[Mh] Termos MeSH secundário: Materiais Biomédicos e Odontológicos/química
Seres Humanos
Polímeros/química
Dióxido de Silício/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomedical and Dental Materials); 0 (Polymers); 7631-86-9 (Silicon Dioxide)
[Em] Mês de entrada:1508
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150124
[St] Status:MEDLINE
[do] DOI:10.3390/s141224029


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[PMID]:25455618
[Au] Autor:Brown C
[Ad] Endereço:Applications Engineer/Dental Specialist, Axsys Dental Solutions, Wixom, Michigan; former Business Manager, Apex Dental Milling, Ann Arbor, Michigan.
[Ti] Título:Laboratory technology 2014: identifying material and equipment trends and changes.
[So] Source:Compend Contin Educ Dent;35(9):707-8, 2014 Oct.
[Is] ISSN:2158-1797
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Materiais Biomédicos e Odontológicos
Laboratórios Odontológicos/tendências
Tecnologia Odontológica/tendências
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomedical and Dental Materials)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:141203
[St] Status:MEDLINE


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[PMID]:24923122
[Au] Autor:Stoiko IV; Béts GV; Béts IG; Karpinskii MIu
[Ti] Título:[Investigation of mechanical properties of materials used for functional stabilization in pilon fractures].
[So] Source:Klin Khir;(2):45-8, 2014 Feb.
[Is] ISSN:0023-2130
[Cp] País de publicação:Ukraine
[La] Idioma:rus
[Ab] Resumo:Existing methods of surgical treatment of the pilon fractures do not provide early functional rehabilitation of patients. The lack of confidence in secure fixation of fragments in significant quantity of patients causes necessity to apply a plaster immobilization during long time. While seeking possibilities of early functional treatment of the pilon fractures there was proposed a theory of "functional stabilization" (instead of "artificial", but necessary plaster immobilization), materials and technologies for its realization. For substantiating, from the biomechanical point of view, of expediency of a new materials (Softcost, Scotchcost) application the data about their physic-chemical properties were adduced, and in particular, there were studied the bowing values, depending on loading, and modules of elasticity of these materials.
[Mh] Termos MeSH primário: Materiais Biomédicos e Odontológicos/química
Teste de Materiais/métodos
Fenômenos Mecânicos
Dispositivos de Fixação Ortopédica/normas
Fraturas da Tíbia/terapia
[Mh] Termos MeSH secundário: Análise de Variância
Seres Humanos
Modelos Teóricos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomedical and Dental Materials)
[Em] Mês de entrada:1407
[Cu] Atualização por classe:161125
[Lr] Data última revisão:
161125
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140614
[St] Status:MEDLINE


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[PMID]:24717980
[Au] Autor:Ramshaw JA; Werkmeister JA; Dumsday GJ
[Ad] Endereço:CSIRO Materials Science and Engineering; Clayton, Australia.
[Ti] Título:Bioengineered collagens: emerging directions for biomedical materials.
[So] Source:Bioengineered;5(4):227-33, 2014 Jul-Aug.
[Is] ISSN:2165-5987
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Mammalian collagen has been widely used as a biomedical material. Nevertheless, there are still concerns about the variability between preparations, particularly with the possibility that the products may transmit animal-based diseases. Many groups have examined the possible application of bioengineered mammalian collagens. However, translating laboratory studies into large-scale manufacturing has often proved difficult, although certain yeast and plant systems seem effective. Production of full-length mammalian collagens, with the required secondary modification to give proline hydroxylation, has proved difficult in E. coli. However, recently, a new group of collagens, which have the characteristic triple helical structure of collagen, has been identified in bacteria. These proteins are stable without the need for hydroxyproline and are able to be produced and purified from E. coli in high yield. Initial studies indicate that they would be suitable for biomedical applications.
[Mh] Termos MeSH primário: Proteínas de Bactérias/química
Materiais Biocompatíveis/química
Materiais Biomédicos e Odontológicos/química
Colágeno/biossíntese
Engenharia de Proteínas
Proteínas Recombinantes/biossíntese
[Mh] Termos MeSH secundário: Hidroxiprolina/química
Proteínas Recombinantes/química
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; REVIEW
[Nm] Nome de substância:
0 (Bacterial Proteins); 0 (Biocompatible Materials); 0 (Biomedical and Dental Materials); 0 (Recombinant Proteins); 9007-34-5 (Collagen); RMB44WO89X (Hydroxyproline)
[Em] Mês de entrada:1505
[Cu] Atualização por classe:170220
[Lr] Data última revisão:
170220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140411
[St] Status:MEDLINE
[do] DOI:10.4161/bioe.28791


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[PMID]:24572865
[Au] Autor:Rohrich RJ
[Ad] Endereço:Dallas, Texas From the Editorial Office of Plastic and Reconstructive Surgery.
[Ti] Título:The process of publishing industry-affiliated articles in Plastic and Reconstructive Surgery.
[So] Source:Plast Reconstr Surg;133(3):757-60, 2014 Mar.
[Is] ISSN:1529-4242
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Políticas Editoriais
Editoração/ética
Editoração/normas
Cirurgia Plástica
[Mh] Termos MeSH secundário: Autoria/normas
Bioética
Materiais Biomédicos e Odontológicos
Conflito de Interesses
Indústria Farmacêutica
Seres Humanos
Revisão da Pesquisa por Pares/ética
Revisão da Pesquisa por Pares/normas
Viés de Publicação
Cirurgia Plástica/normas
[Pt] Tipo de publicação:EDITORIAL
[Nm] Nome de substância:
0 (Biomedical and Dental Materials)
[Em] Mês de entrada:1404
[Cu] Atualização por classe:150624
[Lr] Data última revisão:
150624
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:140228
[St] Status:MEDLINE
[do] DOI:10.1097/PRS.0000000000000036


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[PMID]:23548407
[Au] Autor:Cha KJ; Hong JM; Cho DW; Kim DS
[Ad] Endereço:Department of Mechanical Engineering, Pohang University of Science and Technology POSTECH, San 31 Hyoja-dong Nam-gu, Pohang 790-784, Korea.
[Ti] Título:Enhanced osteogenic fate and function of MC3T3-E1 cells on nanoengineered polystyrene surfaces with nanopillar and nanopore arrays.
[So] Source:Biofabrication;5(2):025007, 2013 Jun.
[Is] ISSN:1758-5090
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:During in vitro culture, cell fate and function, including cell adhesion, morphology, proliferation and differentiation, are affected by surface characteristics, such as geometry, wettability, hardness, chemistry and charge. This study replicated two different types of nanoengineered polystyrene surfaces (NPS) containing nanopillar (NPS-Pi) or nanopore (NPS-Po) arrays by hot embossing and investigated their topographical effects on cell behavior using osteoblast-like MC3T3-E1 cells. To mass-replicate NPS, rigid metal nano-stamps were manufactured by nickel electroforming onto two different nano-templates: (1) a nanopore-arrayed anodic aluminum oxide nano-template using two-step electrochemical oxidation and (2) a nanopillar-arrayed polymer using hot embossing process. The physical and mechanical properties of the NPS, including geometry, wettability, hardness and elastic modulus, were evaluated with the help of field emission-scanning electron microscopy, a contact angle meter, and a nanoindenter. The nanotopography maintained the bulk property, while drastically changing the surface properties. In vitro the NPS had significant effects on MC3T3-E1 cell morphology, attachment, proliferation and osteogenic differentiation compared to a flat substrate due to the altered physical and mechanical surface properties of the nanoengineered surface. Interestingly, the NPS-Po was more effective at enhancing cell proliferation and osteogenesis differentiation. One potential explanation for these results may be that the subcellular binding sites induced by the nanostructures changed the cell morphology and promoted contractile cytoskeletons, thereby enhancing osteogenic differentiation. This, which allows for the cost-effective replication of NPS and the control of cell behavior, has various applications with respect to biomedical and cell surface interaction studies, in addition to enhanced osteogenic cell fate and function.
[Mh] Termos MeSH primário: Nanoporos
Poliestirenos/química
[Mh] Termos MeSH secundário: Óxido de Alumínio/química
Animais
Materiais Biomédicos e Odontológicos
Cálcio/metabolismo
Diferenciação Celular
Linhagem Celular
Proliferação Celular
Forma Celular
Fibronectinas/genética
Fibronectinas/metabolismo
Integrina beta1/genética
Integrina beta1/metabolismo
Camundongos
Nanoestruturas/química
Níquel/química
Osteoblastos/citologia
Osteoblastos/metabolismo
Propriedades de Superfície
Análise Serial de Tecidos
Molhabilidade
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Biomedical and Dental Materials); 0 (Fibronectins); 0 (Integrin beta1); 0 (Polystyrenes); 7OV03QG267 (Nickel); LMI26O6933 (Aluminum Oxide); SY7Q814VUP (Calcium)
[Em] Mês de entrada:1310
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130404
[St] Status:MEDLINE
[do] DOI:10.1088/1758-5082/5/2/025007


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[PMID]:23485002
[Au] Autor:Li L; McKee A
[Ad] Endereço:Peterborough and Stamford Hospitals NHS Foundation Trust, UK. xl228@doctors.org.uk
[Ti] Título:Dental rolls for tendon repair practice.
[So] Source:Ann R Coll Surg Engl;95(2):155, 2013 Mar.
[Is] ISSN:1478-7083
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Educação de Pós-Graduação em Medicina/métodos
Técnicas de Sutura/educação
Materiais de Ensino
Tendões/cirurgia
[Mh] Termos MeSH secundário: Materiais Biomédicos e Odontológicos
Seres Humanos
Tampões Cirúrgicos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Biomedical and Dental Materials)
[Em] Mês de entrada:1305
[Cu] Atualização por classe:140718
[Lr] Data última revisão:
140718
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:130315
[St] Status:MEDLINE
[do] DOI:10.1308/003588413X13511609958055b



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