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[PMID]: 28650789 [Au] Autor: Dotsey RP; Moser EAS; Eckert GJ; Gregory RL [Ti] Título: Effects of Cola-Flavored Beverages and Caffeine on Streptococcus mutans Biofilm Formation and Metabolic Activity. [So] Source: J Clin Pediatr Dent;41(4):294-299, 2017. [Is] ISSN: 1053-4628 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: OBJECTIVE: To examine the effects of cola-flavored beverages and caffeine on growth and metabolism of Streptococcus mutans biofilm. This study was designed to determine if carbonated beverages or caffeine can increase S. mutans growth and biofilm formation and metabolic activity in vitro, potentially leading to increased S. mutans-associated cariogenicity in children that consume them. STUDY DESIGN: Six different cola-flavored products, plus pure caffeine, and pure high fructose corn syrup (HFCS), at different concentrations similar to those in the beverages were tested. A 16-hour culture of S. mutans was treated with different dilutions in bacteriological media. To test for the effect on biofilm formation, the biofilm was stained with crystal violet. The absorbance was determined to evaluate biofilm growth. Biofilm metabolic activity was measured based on biofilm having the ability to reduce XTT to a water-soluble orange compound. RESULTS: The inclusion of HFCS in the beverages, as well as pure HFCS, significantly enhanced bacterial biofilm formation and metabolic activity. Pure caffeine and the presence of caffeine in beverages did not significantly increase biofilm formation, but pure caffeine significantly increased metabolism, and Diet Coke had significantly greater metabolic activity than Caffeine-Free Diet Coke. CONCLUSIONS: HFCS increases both the biofilm formation and metabolism of S. mutans, and caffeine in some cases increases metabolism of S. mutans. [Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento Cafeína/farmacologia Bebidas Gaseificadas/efeitos adversos Cariogênicos/efeitos adversos Cola/efeitos adversos Xarope de Milho Rico em Frutose/farmacologia Streptococcus mutans/crescimento & desenvolvimento Streptococcus mutans/metabolismo [Mh] Termos MeSH secundário: Relação Dose-Resposta a Droga Seres Humanos Oxirredução/efeitos dos fármacos [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (High Fructose Corn Syrup); 3G6A5W338E (Caffeine) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170914 [Lr] Data última revisão: 170914 [Sb] Subgrupo de revista: D [Da] Data de entrada para processamento: 170627 [St] Status: MEDLINE [do] DOI: 10.17796/1053-4628-41.4.294

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[PMID]: 27223133 [Au] Autor: Botelho JN; Villegas-Salinas M; Troncoso-Gajardo P; Giacaman RA; Cury JA [Ad] Endereço: University of Campinas - UNICAMP, Piracicaba Dental School, Department of Physiological Sciences, Piracicaba, SP, Brazil. [Ti] Título: Enamel and dentine demineralization by a combination of starch and sucrose in a biofilm - caries model. [So] Source: Braz Oral Res;30(1), 2016 May 20. [Is] ISSN: 1807-3107 [Cp] País de publicação: Brazil [La] Idioma: eng [Ab] Resumo: Sucrose is the most cariogenic dietary carbohydrate and starch is considered non-cariogenic for enamel and moderately cariogenic for dentine. However, the cariogenicity of the combination of starch and sucrose remains unclear. The aim of this study was to evaluate the effect of this combination on Streptococcus mutans biofilm composition and enamel and dentine demineralization. Biofilms of S. mutans UA159 were grown on saliva-coated enamel and dentine slabs in culture medium containing 10% saliva. They were exposed (8 times/day) to one of the following treatments: 0.9% NaCl (negative control), 1% starch, 10% sucrose, or 1% starch and 10% sucrose (starch + sucrose). To simulate the effect of human salivary amylase on the starch metabolization, the biofilms were pretreated with saliva before each treatment and saliva was also added to the culture medium. Acidogenicity of the biofilm was estimated by evaluating (2 times/day) the culture medium pH. After 4 (dentine) or 5 (enamel) days of growth, biofilms (n = 9) were individually collected, and the biomass, viable microorganism count, and polysaccharide content were quantified. Dentine and enamel demineralization was assessed by determining the percentage of surface hardness loss. Biofilms exposed to starch + sucrose were more acidogenic and caused higher demineralization (p < 0.0001) on either enamel or dentine than those exposed to each carbohydrate alone. The findings suggest that starch increases the cariogenic potential of sucrose. [Mh] Termos MeSH primário: Biofilmes/crescimento & desenvolvimento Cariogênicos/química Esmalte Dentário/química Dentina/química Sacarose na Dieta/química Amido/química Desmineralização do Dente/etiologia [Mh] Termos MeSH secundário: Animais Bovinos Contagem de Colônia Microbiana Esmalte Dentário/microbiologia Dentina/microbiologia Seres Humanos Valores de Referência Saliva/química Saliva/microbiologia Estatísticas não Paramétricas Streptococcus mutans/crescimento & desenvolvimento Fatores de Tempo Desmineralização do Dente/microbiologia Adulto Jovem [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Dietary Sucrose); 9005-25-8 (Starch) [Em] Mês de entrada: 1612 [Cu] Atualização por classe: 161230 [Lr] Data última revisão: 161230 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 160526 [St] Status: MEDLINE

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[PMID]: 27026078 [Au] Autor: Schwendicke F; Diederich C; Paris S [Ad] Endereço: Department of Operative and Preventive Dentistry, Charité - Universitätsmedizin Berlin, Germany. Electronic address: falk.schwendicke@charite.de. [Ti] Título: Restoration gaps needed to exceed a threshold size to impede sealed lesion arrest in vitro. [So] Source: J Dent;48:77-80, 2016 May. [Is] ISSN: 1879-176X [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: OBJECTIVES: After selective excavation, bacteria are sealed beneath restorations. Leaking restorations could maintain carbohydrate-supply, leading to lesion progression and pulp damage. It is unclear if fluid (and thereby carbohydrate) exchange occurs through any interfacial gaps, or if such exchange only occurs in case gaps exceed a certain threshold size. We investigated how different restoration gap sizes impact on survival of sealed bacterial in vitro. METHODS: Bacterially contaminated artificial residual lesions were induced on the pulpo-axial walls of standardized dentin micro-cavities using acetic-acid demineralization and a continuous-culture Lactobacillus rhamnosus biofilm-model. Adhesive restorations with different gap sizes (0/100/200/400 µm) were placed (n=24/group). Restorations were submitted to cyclic loading (42 g/0.2 Hz) under highly cariogenic conditions in a mastication-simulating artificial mouth. After 25 days, the number of sealed viable bacteria was determined as colony-forming units. RESULTS: After 25 days, CFU were significantly reduced in all groups (-99.99%, p<0.001/Mann-Whitney). Significantly more viable bacteria remained in restorations with gaps ≥ 200 µm (p<0.001). CONCLUSIONS: Restoration gaps needed to exceed a threshold size to impede lesion arrest in vitro. There is great need to better understand why such threshold exists and which factors (mastication forces, restoration material, lesion location) could moderate the observed association. CLINICAL SIGNIFICANCE: A certain gap sizes was necessary to allow sufficient fluid exchange for bacterial survival in vitro. It is not possible to deduct clinical recommendations at present. [Mh] Termos MeSH primário: Cárie Dentária/microbiologia Infiltração Dentária/microbiologia Adaptação Marginal Dentária Restauração Dentária Permanente [Mh] Termos MeSH secundário: Ataque Ácido Dentário Animais Fenômenos Fisiológicos Bacterianos Biofilmes/crescimento & desenvolvimento Cariogênicos Bovinos Contagem de Colônia Microbiana Resinas Compostas Preparo da Cavidade Dentária Cimentos Dentários Esmalte Dentário/anatomia & histologia Esmalte Dentário/microbiologia Materiais Dentários/química Adesivos Dentinários Progressão da Doença Lactobacillus rhamnosus/fisiologia Desmineralização do Dente/microbiologia [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Composite Resins); 0 (Dental Cements); 0 (Dental Materials); 0 (Dentin-Bonding Agents) [Em] Mês de entrada: 1705 [Cu] Atualização por classe: 170524 [Lr] Data última revisão: 170524 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 160331 [St] Status: MEDLINE

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[PMID]: 26867225 [Au] Autor: Stegues CG; Arthur RA; Hashizume LN [Ad] Endereço: Faculty of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, RS CEP 90035-003, Brazil. Electronic address: clarissa.stegues@gmail.com. [Ti] Título: Effect of the association of maltodextrin and sucrose on the acidogenicity and adherence of cariogenic bacteria. [So] Source: Arch Oral Biol;65:72-6, 2016 May. [Is] ISSN: 1879-1506 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: OBJECTIVE: The aim was to investigate the effect of maltodextrin and sucrose association on the acidogenic and adherence profiles of cariogenic bacteria. DESIGN: Streptococcus mutans (S. mutans) and Lactobacillus casei (L. casei) were cultivated in culture medium containing maltodextrin, sucrose, maltodextrin-sucrose mixture or glucose. Analyses of the acidogenicity and microbial adherence were conducted in triplicate for each microorganism and tested carbohydrate. RESULTS: For L. casei, maltodextrin, sucrose and maltodextrin-sucrose mixture showed lower acidogenic potential compared to glucose. When the microorganism was S. mutans, sucrose and maltodextrin-sucrose mixture presented higher acidogenic potential compared to maltodextrin and glucose. Microbial adherence analysis revealed higher adherence for S. mutans in presence of sucrose and maltodextrin-sucrose mixture compared to maltodextrin and glucose. For L. casei, all the carbohydrates showed similar adherence percentages. CONCLUSION: The addition of maltodextrin to sucrose does not increase the cariogenicity of sucrose in terms of acidogenicity and adherence of the cariogenic bacteria. [Mh] Termos MeSH primário: Aderência Bacteriana/efeitos dos fármacos Cariogênicos/farmacologia Cárie Dentária/microbiologia Lactobacillus casei/efeitos dos fármacos Polissacarídeos/farmacologia Streptococcus mutans/efeitos dos fármacos Sacarose/farmacologia [Mh] Termos MeSH secundário: Biofilmes/efeitos dos fármacos Combinação de Medicamentos Glucose/farmacologia Concentração de Íons de Hidrogênio Lactobacillus casei/citologia Lactobacillus casei/metabolismo Streptococcus mutans/citologia Streptococcus mutans/metabolismo [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Drug Combinations); 0 (Polysaccharides); 57-50-1 (Sucrose); 7CVR7L4A2D (maltodextrin); IY9XDZ35W2 (Glucose) [Em] Mês de entrada: 1701 [Cu] Atualização por classe: 170123 [Lr] Data última revisão: 170123 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 160212 [St] Status: MEDLINE

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[PMID]: 26838142 [Au] Autor: Nirmala S; Quadar MA; Veluru S [Ad] Endereço: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India. [Ti] Título: pH modulation and salivary sugar clearance of different chocolates in children: A randomized clinical trial. [So] Source: J Indian Soc Pedod Prev Dent;34(1):10-6, 2016 Jan-Mar. [Is] ISSN: 1998-3905 [Cp] País de publicação: India [La] Idioma: eng [Ab] Resumo: BACKGROUND: Sugars that occur naturally in foods and those added in processed foods may act as the source for fermentable carbohydrates and may initiate caries process. Among all the foods consumed by children, chocolates form an important constituent. A wide variety of chocolates are available in the Indian market and very few studies have compared their acidogenicity and salivary sugar clearance. OBJECTIVES: To compare the acidogenicity and salivary sugar clearance of 6 different commercially available chocolates in the Indian market. MATERIALS AND METHODS: Thirty subjects aged 10-15 years were selected randomly from one of the available public schools in Nellore city. Six commercially available chocolates in the Indian market were divided into three groups, unfilled (dark and milk chocolate), filled (wafer and fruit and nuts chocolate), and candy (hard milk and mango-flavored candy) groups. Plaque pH values and salivary sugar clearance rates are assessed at baseline, 5, 10, 15, 20, and 30 min after consumption. All the data obtained were statistically evaluated using independent sample t-test and one-way ANOVA for multiple group comparisons. RESULTS: Mango-flavored candy had maximum fall in plaque pH and least fall in plaque pH was recorded with milk chocolate. Fruit and nuts chocolate had a maximum clearance of salivary sugar and least fall in the salivary sugar clearance was recorded with dark chocolate. When the plaque pH and salivary sugar clearance of all the chocolates were assessed, it was seen that the values were statistically significant at all the time intervals (P < 0.05). CONCLUSION: Dark chocolate had a high fall in pH and milk chocolate had low salivary sugar clearance which signifies that unfilled chocolates are more cariogenic than other chocolates. Even though mango-flavored candy had maximum fall in plaque pH, its salivary sugar clearance was high. [Mh] Termos MeSH primário: Cacau/química Cariogênicos/metabolismo Placa Dentária/metabolismo Saliva/metabolismo Sacarose/metabolismo [Mh] Termos MeSH secundário: Adolescente Metabolismo dos Carboidratos Criança Feminino Seres Humanos Concentração de Íons de Hidrogênio Índia Masculino [Pt] Tipo de publicação: JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL [Nm] Nome de substância: 0 (Cariogenic Agents); 57-50-1 (Sucrose) [Em] Mês de entrada: 1707 [Cu] Atualização por classe: 170705 [Lr] Data última revisão: 170705 [Sb] Subgrupo de revista: D [Da] Data de entrada para processamento: 160204 [St] Status: MEDLINE [do] DOI: 10.4103/0970-4388.175502

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[PMID]: 26767770 [Au] Autor: Yang SY; Kwon JS; Kim KN; Kim KM [Ad] Endereço: Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University, Seoul, Republic of Korea BK21 PLUS Project, Yonsei University College of Dentistry, Seoul, Republic of Korea. [Ti] Título: Enamel Surface with Pit and Fissure Sealant Containing 45S5 Bioactive Glass. [So] Source: J Dent Res;95(5):550-7, 2016 May. [Is] ISSN: 1544-0591 [Cp] País de publicação: United States [La] Idioma: eng [Ab] Resumo: Enamel demineralization adjacent to pit and fissure sealants leads to the formation of marginal caries, which can necessitate the replacement of existing sealants. Dental materials with bioactive glass, which releases ions that inhibit dental caries, have been studied. The purpose of this study was to evaluate the enamel surface adjacent to sealants containing 45S5 bioactive glass (BAG) under simulated microleakage between the material and the tooth in a cariogenic environment. Sealants containing 45S5BAG filler were prepared as follows: 0% 45S5BAG + 50.0% glass (BAG0 group), 12.5% 45S5BAG + 37.5% glass (BAG12.5 group), 25.0% 45S5BAG + 25.0% glass (BAG25.0 group), 37.5% 45S5BAG + 12.5% glass (BAG37.5 group), and 50.0% 45S5BAG + 0% glass (BAG50.0 group). A cured sealant disk was placed over a flat bovine enamel disk, separated by a 60-µm gap, and immersed in lactic acid solution (pH 4.0) at 37 °C for 15, 30, and 45 d. After the storage period, each enamel disk was separated from the cured sealant disk, and the enamel surface was examined with optical 3-dimensional surface profilometer, microhardness tester, and scanning electron microscopy. The results showed a significant increase in roughness and a decrease in microhardness of the enamel surface as the proportion of 45S5BAG decreased (P< 0.05). In the scanning electron microscopy images, enamel surfaces with BAG50.0 showed a smooth surface, similar to those in the control group with distilled water, even after prolonged acid storage. Additionally, an etched pattern was observed on the surface of the demineralized enamel with a decreasing proportion of 45S5BAG. Increasing the 45S5BAG filler contents of the sealants had a significant impact in preventing the demineralization of the enamel surface within microgaps between the material and the tooth when exposed to a cariogenic environment. Therefore, despite some marginal leakage, these novel sealants may be effective preventive dental materials for inhibiting secondary caries at the margins. [Mh] Termos MeSH primário: Cerâmica/química Esmalte Dentário/ultraestrutura Vidro/química Selantes de Fossas e Fissuras/química [Mh] Termos MeSH secundário: Animais Bis-Fenol A-Glicidil Metacrilato/química Cariogênicos/química Bovinos Resinas Compostas/química Infiltração Dentária/patologia Dureza Concentração de Íons de Hidrogênio Imagem Tridimensional/métodos Ácido Láctico/química Teste de Materiais Microscopia Eletrônica de Varredura Imagem Óptica/métodos Polietilenoglicóis/química Ácidos Polimetacrílicos/química Propriedades de Superfície Temperatura Ambiente Fatores de Tempo Desmineralização do Dente/patologia [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Clinpro Sealant); 0 (Composite Resins); 0 (Pit and Fissure Sealants); 0 (Polymethacrylic Acids); 0 (bioactive glass 45S5); 14I47YJ5EY (triethylene glycol dimethacrylate); 30IQX730WE (Polyethylene Glycols); 33X04XA5AT (Lactic Acid); 454I75YXY0 (Bisphenol A-Glycidyl Methacrylate) [Em] Mês de entrada: 1609 [Cu] Atualização por classe: 161126 [Lr] Data última revisão: 161126 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 160116 [St] Status: MEDLINE [do] DOI: 10.1177/0022034515626116

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[PMID]: 26689611 [Au] Autor: Mei ML; Zhao IS; Ito L; Lo EC; Chu CH [Ad] Endereço: Faculty of Dentistry, the University of Hong Kong, Hong Kong SAR, China. [Ti] Título: Prevention of secondary caries by silver diamine fluoride. [So] Source: Int Dent J;66(2):71-7, 2016 Apr. [Is] ISSN: 1875-595X [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: PURPOSE: This study aimed to investigate the use of 38% silver diamine fluoride (SDF) as a treatment for preventing secondary caries in glass ionomer cement (GIC) and composite resin (CR) restorations. METHODS: Six extracted human sound premolars were collected. Four cavities (4 × 2 × 2 mm(3) ) were prepared on each premolar and then allocated to the following restoration groups: group 1, SDF conditioning and GIC restoration; group 2, GIC restoration; group 3, SDF conditioning and CR restoration; and group 4, CR restoration. After thermal cycling and sterilisation, the teeth were soaked in a 5% sucrose solution containing Streptococcus mutans and Lactobacillus acidophilus for 28 days. Micro-computed tomography was used to study demineralisation. The outer lesion depth (OLD) and wall lesion depth (WLD) of the tooth-restoration interface were measured. The OLD and WLD were directly related to the extent of secondary caries. Two-way analysis of variance was used to analyse the effects of SDF conditioning and restorative materials on OLD. RESULTS: The mean ± standard deviation OLD values were 156 ± 45 µm, 235 ± 33 µm, 153 ± 20 µm and 232 ± 24 µm for groups 1-4, respectively. The OLD was less in restorations with SDF conditioning (P < 0.001) than in those without SDF conditioning. No interaction effect on OLD was found between the restorative materials and SDF conditioning (P = 0.062). The WLD was detected only in groups 3 and 4. CLINICAL SIGNIFICANCE: Conditioning with 38% SDF can increase resistance of GIC and CR restorations to secondary caries. [Mh] Termos MeSH primário: Cariostáticos/uso terapêutico Cárie Dentária/prevenção & controle Restauração Dentária Permanente/métodos Compostos de Amônio Quaternário/uso terapêutico [Mh] Termos MeSH secundário: Adolescente Cariogênicos/efeitos adversos Resinas Compostas/química Cárie Dentária/etiologia Preparo da Cavidade Dentária/métodos Esmalte Dentário/efeitos dos fármacos Materiais Dentários/química Dentina/efeitos dos fármacos Cimentos de Ionômeros de Vidro/química Seres Humanos Imagem Tridimensional/métodos Técnicas In Vitro Lactobacillus acidophilus/fisiologia Distribuição Aleatória Recidiva Streptococcus mutans/fisiologia Sacarose/efeitos adversos Temperatura Ambiente Fatores de Tempo Desmineralização do Dente/etiologia Microtomografia por Raio-X/métodos [Pt] Tipo de publicação: COMPARATIVE STUDY; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Cariostatic Agents); 0 (Composite Resins); 0 (Dental Materials); 0 (Glass Ionomer Cements); 0 (Quaternary Ammonium Compounds); 57-50-1 (Sucrose); DDU19UEV1Y (silver diamine fluoride) [Em] Mês de entrada: 1608 [Cu] Atualização por classe: 160716 [Lr] Data última revisão: 160716 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 151223 [St] Status: MEDLINE [do] DOI: 10.1111/idj.12207

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[PMID]: 26451810 [Au] Autor: Fernández CE; Giacaman RA; Tenuta LM; Cury JA [Ad] Endereço: Piracicaba Dental School, University of Campinas, Piracicaba, Brazil. [Ti] Título: Effect of the Probiotic Lactobacillus rhamnosus LB21 on the Cariogenicity of Streptococcus mutans UA159 in a Dual-Species Biofilm Model. [So] Source: Caries Res;49(6):583-90, 2015. [Is] ISSN: 1421-976X [Cp] País de publicação: Switzerland [La] Idioma: eng [Ab] Resumo: Despite promising results using probiotics, evidence of the preventive effect on enamel demineralization is insufficient and the cariogenic potential of probiotics is still controversial. Probiotics could affect biofilm formation and interfere with adherence, growth or coaggregation with Streptococcus mutans in biofilms. However, most of the studies have been conducted using planktonic bacteria. Hence, the aim of the study was to assess the effect of probiotic bacteria on the cariogenicity of S. mutans using an in vitro biofilm caries model on enamel. Single-species biofilms (S. mutans UA159, SM or Lactobacillus rhamnosus LB21, LB) or dual-species biofilms simultaneously inoculated (SM + LB) or LB inoculated 8 h after SM (SM x2192; LB) were grown for 96 h. Biofilms were formed on bovine enamel saliva-coated slabs of known surface hardness (SH) and immersed in culture media. Biofilms were exposed 8 times per day to 10% sucrose. Medium pH was monitored twice daily as a biofilm acidogenicity indicator. After 96 h, biofilms were collected to determine biomass and bacteria viability. Slab demineralization was calculated as percentage of SH loss (%SHL). Additionally, the model was tested with different concentrations of the initial inoculum (103, 106, 108 cells/ml) and different adhesion times (2 or 8 h). The dual-species biofilm revealed no LB effects on SM cariogenicity, without changes in acidogenicity or %SHL among groups (p > 0.05, n = 12). Lack of activity of LB on SM cariogenicity persisted even when 105 times higher concentration of the probiotic was tested. Coaggregation was not observed. In conclusion, findings suggest that LB does not reduce cariogenicity of SM in a validated experimental caries model. [Mh] Termos MeSH primário: Biofilmes Lactobacillus rhamnosus/fisiologia Streptococcus mutans/fisiologia [Mh] Termos MeSH secundário: Animais Cariogênicos Bovinos Probióticos Desmineralização do Dente [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Cariogenic Agents) [Em] Mês de entrada: 1709 [Cu] Atualização por classe: 170918 [Lr] Data última revisão: 170918 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 151010 [St] Status: MEDLINE [do] DOI: 10.1159/000439315

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[PMID]: 26351745 [Au] Autor: Lee EJ; Hwang IK; Paik DI; Jin BH [Ad] Endereço: Dept. of Preventive & Social Dentistry, School of Dentistry, Seoul National University, South Korea; Dept. of Food & Nutrition, College of Human Ecology, Seoul National University, South Korea. [Ti] Título: The cariogenicity of hydrolyzed starch foods by measuring the polyacrylamide hydroxyapatite (PAHA) disc. [So] Source: Arch Oral Biol;60(11):1632-8, 2015 Nov. [Is] ISSN: 1879-1506 [Cp] País de publicação: England [La] Idioma: eng [Ab] Resumo: OBJECTIVES: This study measured the degree of demineralization of starch foods affected by hydrolyzed starch in total starch using the polyacrylamide hydroxyapatite (PAHA) disc. DESIGN: A total of 10 ml of test food was added to a PAHA disc and 5 ml artificial saliva, followed by inoculation with 1 µl of S. mutans and incubation at 37 °C for 180 min. The demineralization effects were then determined using CLSM. RESULTS: The proportion of hydrolyzed starch in total starch in potato increased over time, while hydrolyzed starch in other test food decreased. When the amount of hydrolyzed starch in total starch increased after 180 min (p=0.000), the surface roughness of the PAHA disc in potato was significantly decreased. Wheat-based sugary snacks, such as chips and cookie, had relatively high cariogenic potentials, whereas baked potato had a relatively low cariogenic potential. CONCLUSIONS: Hydrolyzed starch in total starch increased over time, and cariogenic potential was notably decreased. Measurement of PAHA disc may be a valid method for assessing the cariogenic potential of hydrolyzed starch foods. [Mh] Termos MeSH primário: Resinas Acrílicas/química Cariogênicos/análise Durapatita/química Lanches Amido/química [Mh] Termos MeSH secundário: Análise de Alimentos/métodos Glucose/química Hidrólise Microscopia Confocal Sacarose/química Desmineralização do Dente [Pt] Tipo de publicação: JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T [Nm] Nome de substância: 0 (Acrylic Resins); 0 (Cariogenic Agents); 57-50-1 (Sucrose); 9003-05-8 (polyacrylamide); 9005-25-8 (Starch); 91D9GV0Z28 (Durapatite); IY9XDZ35W2 (Glucose) [Em] Mês de entrada: 1608 [Cu] Atualização por classe: 151001 [Lr] Data última revisão: 151001 [Sb] Subgrupo de revista: D; IM [Da] Data de entrada para processamento: 150910 [St] Status: MEDLINE

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[PMID]: 26192983 [Au] Autor: Ma MS; Blanksma NG [Ti] Título: [Stevia in the fight against dental caries]. [Ti] Título: Stevia in de strijd tegen cariës.. [So] Source: Ned Tijdschr Tandheelkd;122(1):51-5, 2015 Jan. [Is] ISSN: 0028-2200 [Cp] País de publicação: Netherlands [La] Idioma: dut [Ab] Resumo: Stevia is a natural, non-caloric sweetener of plant origin. The sweetening power of stevia is several hundred times larger than that of table sugar (sucrose). On the basis of available research, the European Food Safety Authority concluded that stevia is safe for human consumption. Since then, stevia has been approved as a sweetener for the European market. As a substitute for sucrose, stevia can contribute to a reduced caloric intake and can play a role in the prevention and/or treatment of metabolic disorders. In addition, stevia is non-cariogenic and is, moreover, affordable. Promoting the consumption of stevia can therefore be a preventive means of fighting dental caries. [Mh] Termos MeSH primário: Cárie Dentária/prevenção & controle Stevia/química Edulcorantes/administração & dosagem [Mh] Termos MeSH secundário: Cariogênicos/administração & dosagem Cariogênicos/efeitos adversos Seres Humanos Edulcorantes/efeitos adversos [Pt] Tipo de publicação: JOURNAL ARTICLE [Nm] Nome de substância: 0 (Cariogenic Agents); 0 (Sweetening Agents) [Em] Mês de entrada: 1610 [Cu] Atualização por classe: 161230 [Lr] Data última revisão: 161230 [Sb] Subgrupo de revista: D [Da] Data de entrada para processamento: 150721 [St] Status: MEDLINE [do] DOI: 10.5177/ntvt.2015.01.14161

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