Base de dados : MEDLINE
Pesquisa : D25.720.327 [Categoria DeCS]
Referências encontradas : 1419 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 142 ir para página                         

  1 / 1419 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28457658
[Au] Autor:Huong KH; Azuraini MJ; Aziz NA; Amirul AA
[Ad] Endereço:Malaysian Institute of Pharmaceuticals and Nutraceuticals, NIBM, 11700 Gelugor, Penang, Malaysia.
[Ti] Título:Pilot scale production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) biopolymers with high molecular weight and elastomeric properties.
[So] Source:J Biosci Bioeng;124(1):76-83, 2017 Jul.
[Is] ISSN:1347-4421
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [(P(3HB-co-4HB)] copolymer receives attention as next generation biomaterial in medical application. However, the exploitation of the copolymer is still constrained since such copolymer has not yet successfully been performed in industrial scale production. In this work, we intended to establish pilot production system of the copolymer retaining the copolymer quality which has recently discovered to have novel characteristic from lab scale fermentation. An increase of agitation speed has significantly improved the copolymer accumulation efficiency by minimizing the utilization of substrates towards cell growth components. This is evidenced by a drastic increase of PHA content from 28 wt% to 63 wt% and PHA concentration from 3.1 g/L to 6.5 g/L but accompanied by the reduction of residual biomass from 8.0 g/L to 3.8 g/L. Besides, fermentations at lower agitation and aeration have resulted in reduced molecular weight and mechanical strength of the copolymer, suggesting the role of sufficient oxygen supply efficiency in improving the properties of the resulting copolymers. The K a-based scale-up fermentation was performed successfully in maintaining the yield and the quality of the copolymers produced without a drastic fluctuation. This suggests that the scale-up based on the K a values supported the fermentation system of P(3HB-co-4HB) copolymer production in single-stage using mixed-substrate cultivation strategy.
[Mh] Termos MeSH primário: Elastômeros/química
Elastômeros/metabolismo
Hidroxibutiratos/química
Hidroxibutiratos/metabolismo
Poliésteres/química
Poliésteres/metabolismo
[Mh] Termos MeSH secundário: Biomassa
Cupriavidus/metabolismo
Fermentação
Peso Molecular
Projetos Piloto
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 0 (Hydroxybutyrates); 0 (Polyesters); 117068-64-1 (poly(3-hydroxybutyrate-co-4-hydroxybutyrate))
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180104
[Lr] Data última revisão:
180104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  2 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29074755
[Au] Autor:Winey KI
[Ad] Endereço:Department of Materials Science and Engineering, University of Pennsylvania, Philadelphia, PA 19104, USA. winey@seas.upenn.edu.
[Ti] Título:Designing tougher elastomers with ionomers.
[So] Source:Science;358(6362):449-450, 2017 10 27.
[Is] ISSN:1095-9203
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Elastômeros
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; COMMENT
[Nm] Nome de substância:
0 (Elastomers)
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171028
[St] Status:MEDLINE
[do] DOI:10.1126/science.aap8114


  3 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28791809
[Au] Autor:Kardach H; Biedziak B; Olszewska A; Golusinska-Kardach E; Sokalski J
[Ad] Endereço:Division of Facial Malformation, Department of Dental Surgery, Poznan University of Medical Sciences, Poland.
[Ti] Título:The mechanical strength of orthodontic elastomeric memory chains and plastic chains: An in vitro study.
[So] Source:Adv Clin Exp Med;26(3):373-378, 2017 May-Jun.
[Is] ISSN:1899-5276
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: The loss of physical properties of orthodontic chains has been a topic of discussion among scientists and clinicians, motivating efforts to improve elastic materials and minimize the decrease of force. Orthodontic companies have introduced memory elastomers, which, according to the manufacturers, have improved mechanical properties. OBJECTIVES: The aim of the study was to evaluate the effects of stretching elastomeric chains submerged in 37°C artificial saliva. MATERIAL AND METHODS: The study assessed 2 types of chains. The first phase of the study evaluated 1) the tensile strength of the chains; and 2) elongation at the time of tearing in an environment outside of the oral cavity (without exposition). The second phase of the study evaluated 1) permanent deformation after stretching; 2) elongation at the time of tearing; and 3) the tensile strength of the chain in conditions similar to those present in the oral cavity. RESULTS: In the experiments using artificial saliva, pronounced force decay was observed in the plastic chain, in which, after just 7 days, force decreased almost by half compared to the initial value, with a continuous downward trend. The memory chain, however, showed increased elasticity, and after the first week of exposition the force decay at the time of tearing was around 20% of the initial value. Force decay at the time of tearing remained at a steady level between 14.4 and 25.4% throughout the whole period of exposition. In the plastic chain this value oscillated between 50.3 and 55.9%. In the experiments assessing permanent deformation of the chains performed after each week of exposition, the specimens prepared from the memory chain stretched from 8 cm to approximately 9.5 cm after exposition, while the specimens prepared from the plastic chain stretched to approximately 13 cm. CONCLUSIONS: Memory chains are more effective in orthodontic treatment due to diminished loss of mechanical and elastic capabilities, when compared to plastic chains.
[Mh] Termos MeSH primário: Elastômeros/química
Plásticos/química
Polímeros/química
[Mh] Termos MeSH secundário: Elasticidade
Seres Humanos
Teste de Materiais/métodos
Boca/química
Aparelhos Ortodônticos
Saliva Artificial/química
Estresse Mecânico
Resistência à Tração
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 0 (Plastics); 0 (Polymers); 0 (Saliva, Artificial); 0 (elastomeric)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171004
[Lr] Data última revisão:
171004
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170810
[St] Status:MEDLINE
[do] DOI:10.17219/acem/61957


  4 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:28678968
[Au] Autor:Henriques JFC; Higa RH; Semenara NT; Janson G; Fernandes TMF; Sathler R
[Ad] Endereço:Universidade de São Paulo - USP, Bauru Dental School, Department of Orthodontics, Bauru, SP, Brazil.
[Ti] Título:Evaluation of deflection forces of orthodontic wires with different ligation types.
[So] Source:Braz Oral Res;31:e49, 2017 Jul 03.
[Is] ISSN:1807-3107
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:The aim of this study was to evaluate deflection forces of orthodontic wires of different alloys engaged into conventional brackets using several ligation types. Stainless steel, conventional superelastic nickel-titanium and thermally activated nickel-titanium archwires tied into conventional brackets by a ring-shaped elastomeric ligature (RSEL), a 8-shaped elastomeric ligature (8SEL) and a metal ligature (ML) were tested. A clinical simulation device was created especially for this study and forces were measured with an Instron Universal Testing Machine. For the testing procedure, the block representing the maxillary right central incisor was moved 0.5 and 1 mm bucco-lingually at a constant speed of 2 mm/min, and the forces released by the wires were recorded, in accordance with the ISO 15841 guidelines. In general, the RSEL showed lighter forces, while 8SEL and ML showed higher values. At the 0.5 mm deflection, the 8SEL presented the greatest force, but at the 1.0 mm deflection the ML had a statistically similar force. Based on our evaluations, to obtain lighter forces, the thermally activated nickel-titanium wire with the RSEL are recommended, while the steel wire with the 8SEL or the ML are recommended when larger forces are desired. The ML exhibited the highest force increase with increased deflections, compared with the elastomeric ligatures.
[Mh] Termos MeSH primário: Desenho de Aparelho Ortodôntico/métodos
Braquetes Ortodônticos
Fios Ortodônticos
[Mh] Termos MeSH secundário: Análise de Variância
Elasticidade
Elastômeros/química
Fricção
Teste de Materiais
Níquel/química
Valores de Referência
Aço Inoxidável/química
Titânio/química
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 12035-60-8 (titanium nickelide); 12597-68-1 (Stainless Steel); 7OV03QG267 (Nickel); D1JT611TNE (Titanium)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170706
[St] Status:MEDLINE


  5 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28554457
[Au] Autor:Nakamura M; Kawanabe N; Kataoka T; Murakami T; Yamashiro T; Kamioka H
[Ad] Endereço:Department of Orthodontics, Okayama University Hospital, Okayama, Japan. Electronic address: nakamurama@okayama-u.ac.jp.
[Ti] Título:Comparative evaluation of treatment outcomes between temporary anchorage devices and Class III elastics in Class III malocclusions.
[So] Source:Am J Orthod Dentofacial Orthop;151(6):1116-1124, 2017 Jun.
[Is] ISSN:1097-6752
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:INTRODUCTION: Our objective was to elucidate the differences in treatment outcomes caused by the different mechanics of temporary anchorage devices (TADs) and Class III elastics in patients with Class III malocclusions. METHODS: Records of 23 patients with Angle Class III malocclusion were selected retrospectively. All had been treated with nonextraction comprehensive orthodontic treatment; 11 were treated with TADs and 12 with Class III elastics. Pretreatment and posttreatment lateral cephalograms were used for evaluation of the treatment outcomes. A paired t test and a Student t test were used for statistical analysis. RESULTS: In both groups, proper overjet and Class I molar relationships were achieved, and the occlusal plane was rotated counterclockwise. In the elastics group, distal tipping of the mandibular molars, extrusion of the mandibular incisors and maxillary molars, clockwise rotation of the mandibular plane angle, and increased ANB angle were observed. In the TADs group, distal tipping and intrusion of the mandibular molars, bodily movement of the mandibular incisors, and reduced mandibular plane angle were observed. CONCLUSIONS: In nonextraction treatment for Class III malocclusions, the mandibular plane angle was increased in the elastics group, whereas it was decreased in TADs group. Thus, we suggest that Class III elastics are preferred for low-angle, short-face patients, whereas TADs are preferred for high-angle, long-face patients.
[Mh] Termos MeSH primário: Má Oclusão de Angle Classe III/terapia
Procedimentos de Ancoragem Ortodôntica/instrumentação
Aparelhos Ortodônticos Removíveis
[Mh] Termos MeSH secundário: Adolescente
Adulto
Cefalometria
Elastômeros
Feminino
Seres Humanos
Masculino
Meia-Idade
Desenho de Aparelho Ortodôntico
Estudos Retrospectivos
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170822
[Lr] Data última revisão:
170822
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170531
[St] Status:MEDLINE


  6 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28415424
[Au] Autor:Feng C; Du Y; Li Y; Lei B
[Ad] Endereço:School of Chemistry and Chemical Engineering, Zhoukou Normal University, Zhoukou 466000, China.
[Ti] Título:Development of strong, biodegradable and highly elastomeric polycitrate-gelatin hybrid polymer with enhanced cellular biocompatibility.
[So] Source:Mater Sci Eng C Mater Biol Appl;75:1339-1342, 2017 Jun 01.
[Is] ISSN:1873-0191
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Native human tissues possess incomparable biological performance due to their strong and viscoelastic mechanical properties, and biocompatible compositions. Herein, by a thermal polymerization and solvent hybridization method, we develop biomimetic polycitrate-gelatin hybrid polymers (PC-GT) with strong mechanical properties and tailored elastomeric behavior for tissue regeneration applications. The incorporation of gelatin significantly enhanced the mechanical properties and cellular biocompatibility of PC. PC-GT hybrids demonstrated the 135 times (from 7.5 to 1015MPa) and 11 times (from 4 to 46MPa) improvement for the elastomeric modulus and tensile strength respectively as compared with PC elastomers, while showing controlled stretchable and elastomeric behavior. In addition, PC-GT hybrids significantly improved the fibroblasts (L929) attachment and proliferation, suggesting their high biocompatibility. This study may provide a novel strategy to design biocompatible hybrid polymers with strong and elastomeric behavior for tissue regeneration and stretchable electronic devices applications.
[Mh] Termos MeSH primário: Elastômeros
Fibroblastos/metabolismo
Gelatina
[Mh] Termos MeSH secundário: Animais
Linhagem Celular
Ácido Cítrico/química
Ácido Cítrico/farmacologia
Elastômeros/química
Elastômeros/farmacologia
Gelatina/química
Gelatina/farmacologia
Teste de Materiais
Camundongos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 2968PHW8QP (Citric Acid); 9000-70-8 (Gelatin)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170724
[Lr] Data última revisão:
170724
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170419
[St] Status:MEDLINE


  7 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28211327
[Au] Autor:Gartiser S; Heisterkamp I; Schoknecht U; Burkhardt M; Ratte M; Ilvonen O; Brauer F; Brückmann J; Dabrunz A; Egeler P; Eisl AM; Feiler U; Fritz I; König S; Lebertz H; Pandard P; Pötschke G; Scheerbaum D; Schreiber F; Soldán P; Weiß R; Weltens R
[Ad] Endereço:Hydrotox GmbH, Freiburg, Germany. Electronic address: gartiser@hydrotox.de.
[Ti] Título:Results from a round robin test for the ecotoxicological evaluation of construction products using two leaching tests and an aquatic test battery.
[So] Source:Chemosphere;175:138-146, 2017 May.
[Is] ISSN:1879-1298
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:A European round robin test according to ISO 5725-2 was conceptually prepared, realised, and evaluated. The aim was to determine the inter-laboratory variability of the overall process for the ecotoxicological characterization of construction products in eluates and bioassays. To this end, two construction products BAM-G1 (granulate) and HSR-2 (roof sealing sheet), both made of EPDM polymers (rubber), were selected. The granular construction product was eluted in a one stage batch test, the planar product in the Dynamic Surface Leaching test (DSLT). A total of 17 laboratories from 5 countries participated in the round robin test: Germany (12), Austria (2), Belgium (1), Czech Republic (1) and France (1). A test battery of four standardised ecotoxicity tests with algae, daphnia, luminescent bacteria and zebrafish eggs was used. As toxicity measures, EC50 and LID values were calculated. All tests, except the fish egg test, were basically able to demonstrate toxic effects and the level of toxicity. The reproducibility of test results depended on the test specimens and the test organisms. Generally, the variability of the EC50 or LID values increased with the overall level of toxicity. For the very toxic BAM-G1 eluate a relative high variability of CV = 73%-110% was observed for EC50 in all biotests, while for the less toxic HSR-2 eluate the reproducibility of EC50 varied with sensitivity: it was very good (CV = 9.3%) for the daphnia test with the lowest sensitivity, followed by the algae test (CV = 36.4%). The luminescent bacteria test, being the most sensitive bioassay for HSR-2 Eluate, showed the highest variability (CV = 74.8%). When considering the complex overall process the reproducibility of bioassays with eluates from construction products was acceptable.
[Mh] Termos MeSH primário: Ecotoxicologia/métodos
Testes de Toxicidade/métodos
Poluentes Químicos da Água/toxicidade
[Mh] Termos MeSH secundário: Animais
Bactérias/efeitos dos fármacos
Bioensaio/métodos
Bioensaio/normas
Daphnia/efeitos dos fármacos
Ecotoxicologia/normas
Ovos
Elastômeros/toxicidade
Etilenos/toxicidade
Variações Dependentes do Observador
Reprodutibilidade dos Testes
Borracha/toxicidade
Estramenópilas/efeitos dos fármacos
Testes de Toxicidade/normas
Poluentes Químicos da Água/análise
Peixe-Zebra
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 0 (Ethylenes); 0 (Water Pollutants, Chemical); 0 (ethylene-propylene-diene-monomer); 9006-04-6 (Rubber)
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170721
[Lr] Data última revisão:
170721
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170218
[St] Status:MEDLINE


  8 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28199759
[Au] Autor:Huang J; Zhang L; Tang Z; Wu S; Ning N; Sun H; Guo B
[Ad] Endereço:Department of Polymer Materials and Engineering, South China University of Technology, Guangzhou, 510640, P. R. China.
[Ti] Título:Bioinspired Design of a Robust Elastomer with Adaptive Recovery via Triazolinedione Click Chemistry.
[So] Source:Macromol Rapid Commun;38(7), 2017 Apr.
[Is] ISSN:1521-3927
[Cp] País de publicação:Germany
[La] Idioma:eng
[Ab] Resumo:It is a significant but challenging task to simultaneously reinforce and functionalize diene rubbers. Inspired by "sacrificial bonds", the authors engineer sacrificial hydrogen bonds formed by pendent urazole groups in crosslinked solution-polymerized styrene butadiene rubber (SSBR) via triazolinedione click chemistry. This post-crosslinking modification reveals the effects of the sacrificial bonds based on a consistent covalent network. The "cage effect" of the pre-crosslinked network facilitates the heterogeneous distribution of urazole groups, leading to the formation of hydrogen-bonded multiplets. These multiplets further aggregate into clusters with vicinal trapped polymer segments that form microphase separation from the SSBR matrix with a low content of urazole groups. The clusters based on hydrogen bonds, serving as sacrificial bonds, promote energy dissipation, significantly improving the mechanical properties of the modified SSBR, and enable an additional wide transition temperature region above room temperature, which endows the modified SSBR with promising triple-shape memory behavior.
[Mh] Termos MeSH primário: Butadienos/química
Butadienos/síntese química
Química Click
Elastômeros/química
Elastômeros/síntese química
Estirenos/química
Estirenos/síntese química
Triazóis/química
[Mh] Termos MeSH secundário: Biomimética
Ligações de Hidrogênio
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Butadienes); 0 (Elastomers); 0 (Styrenes); 0 (Triazoles); 61789-96-6 (styrene-butadiene rubber)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170425
[Lr] Data última revisão:
170425
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170216
[St] Status:MEDLINE
[do] DOI:10.1002/marc.201600678


  9 / 1419 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28104370
[Au] Autor:Rodriguez S; Gonzales KN; Romero EG; Troncoso OP; Torres FG
[Ad] Endereço:Department of Mechanical Engineering, Pontificia Universidad Católica del Perú, Av. Universitaria 1801, Lima, 32, Peru.
[Ti] Título:Unusual reversible elastomeric gels from Nostoc commune.
[So] Source:Int J Biol Macromol;97:411-417, 2017 Apr.
[Is] ISSN:1879-0003
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Nostoc commune cyanobacteria grow in extreme conditions of desiccation and nutrient-poor soils. Their colonies form spherical gelatinous bodies are composed of a variety of polysaccharides that allow them to store water and nutrients. In this paper, we study this type of biological gel that shows characteristics of both chemical and physical gels. The structure of this gel was assessed by means of scanning electron microscopy, plate-plate rheometry, Fourier transform infrared spectroscopy and absorption/desorption tests. The storage modulus of this gel was found to be frequency independent, as is usual for chemical gels. The stress sweeps showed a reversible stress softening behaviour that was explained in terms of the physical nature of the interactions of this network. The high density of physical crosslinks probably allows this physical network to behave as a highly elastomeric chemical network, limiting the relaxation of individual chains. On the other hand, reversibility is associated with the physical nature of its bonds.
[Mh] Termos MeSH primário: Elastômeros/química
Nostoc commune/química
[Mh] Termos MeSH secundário: Géis
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Elastomers); 0 (Gels)
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170412
[Lr] Data última revisão:
170412
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170121
[St] Status:MEDLINE


  10 / 1419 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28077353
[Ti] Título:Robert Wood.
[So] Source:BMJ;356:j125, 2017 Jan 11.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Cirurgia Geral/história
[Mh] Termos MeSH secundário: Bandagens
Doenças Mamárias/história
Doenças Mamárias/terapia
Elastômeros
Cirurgia Geral/educação
História do Século XX
História do Século XXI
Seres Humanos
Reino Unido
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE; PORTRAITS
[Ps] Nome de pessoa como assunto:Wood R
[Nm] Nome de substância:
0 (Elastomers)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170113
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j125



página 1 de 142 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde