Base de dados : MEDLINE
Pesquisa : E01.370.350.515.666.450 [Categoria DeCS]
Referências encontradas : 210 [refinar]
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[PMID]:28934329
[Au] Autor:Gluck JM; Herren AW; Yechikov S; Kao HKJ; Khan A; Phinney BS; Chiamvimonvat N; Chan JW; Lieu DK
[Ad] Endereço:Division of Cardiovascular Medicine, Department of Internal Medicine, University of California Davis; Davis, CA, United States of America.
[Ti] Título:Biochemical and biomechanical properties of the pacemaking sinoatrial node extracellular matrix are distinct from contractile left ventricular matrix.
[So] Source:PLoS One;12(9):e0185125, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Extracellular matrix plays a role in differentiation and phenotype development of its resident cells. Although cardiac extracellular matrix from the contractile tissues has been studied and utilized in tissue engineering, extracellular matrix properties of the pacemaking sinoatrial node are largely unknown. In this study, the biomechanical properties and biochemical composition and distribution of extracellular matrix in the sinoatrial node were investigated relative to the left ventricle. Extracellular matrix of the sinoatrial node was found to be overall stiffer than that of the left ventricle and highly heterogeneous with interstitial regions composed of predominantly fibrillar collagens and rich in elastin. The extracellular matrix protein distribution suggests that resident pacemaking cardiomyocytes are enclosed in fibrillar collagens that can withstand greater tensile strength while the surrounding elastin-rich regions may undergo deformation to reduce the mechanical strain in these cells. Moreover, basement membrane-associated adhesion proteins that are ligands for integrins were of low abundance in the sinoatrial node, which may decrease force transduction in the pacemaking cardiomyocytes. In contrast to extracellular matrix of the left ventricle, extracellular matrix of the sinoatrial node may reduce mechanical strain and force transduction in pacemaking cardiomyocytes. These findings provide the criteria for a suitable matrix scaffold for engineering biopacemakers.
[Mh] Termos MeSH primário: Matriz Extracelular/metabolismo
Ventrículos do Coração/metabolismo
Nó Sinoatrial/metabolismo
[Mh] Termos MeSH secundário: Animais
Membrana Basal/química
Membrana Basal/metabolismo
Membrana Basal/ultraestrutura
Relógios Biológicos/fisiologia
Fenômenos Biomecânicos
Colágeno/metabolismo
Colágeno/ultraestrutura
Elasticidade
Elastina/metabolismo
Elastina/ultraestrutura
Matriz Extracelular/química
Matriz Extracelular/ultraestrutura
Fibronectinas/metabolismo
Fibronectinas/ultraestrutura
Imunofluorescência
Ventrículos do Coração/química
Ventrículos do Coração/ultraestrutura
Espectrometria de Massas
Microscopia de Força Atômica
Microscopia Eletroquímica de Varredura
Miócitos Cardíacos/química
Miócitos Cardíacos/metabolismo
Proteoma
Proteômica
Nó Sinoatrial/química
Nó Sinoatrial/ultraestrutura
Suínos
Resistência à Tração
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Fibronectins); 0 (Proteome); 9007-34-5 (Collagen); 9007-58-3 (Elastin)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170922
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0185125


  2 / 210 MEDLINE  
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[PMID]:28681365
[Au] Autor:Shimamura S; Kawai K; Odontuya D; Ichihashi T
[Ad] Endereço:Department of Ophthalmology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-1193, Japan. ko_haru_meg_love@yahoo.co.jp.
[Ti] Título:A Comparison of Characteristic Properties and Qualitative Difference between Three Kinds of Triamcinolone Acetonide.
[So] Source:Tokai J Exp Clin Med;42(2):67-70, 2017 Jul 20.
[Is] ISSN:2185-2243
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To conduct a study comparing 3 triamcinolone acetonide preparations in terms of their particle surface observed with a scanning electron microscope, their particle size distribution, and sedimentation in order to discuss their ability to facilitate visualization during vitreous surgery and the clinical results. METHODS: Kenacort-A®, the newer form of MaQaid, and the older form of MaQaid® were used. A scanning electron microscope and a measuring device were used. Sedimentation was measured based on ultraviolet and visible light absorption spectra. RESULTS: Observation of the particle surface revealed that small particles of the older form of MaQaid® had clumped together, and they contained numerous voids. It had a small mean particle dia (almost the same size as the newer form of MaQaid® and Kenacort-A). Kenacort-A was dispersed while the older form of MaQaid® had numerous clumps and ascending particles, and a large sedimentation volume. Small sedimentation volume and few clumps were noted on the newer form of MaQaid®. CONCLUSION: The newer form of MaQaid® had a particle distribution like that of Kenacort-A®, so it should provide good visibility. Moreover, it is free of preservatives, so it may prove to be a useful aid to visualize the vitreous during vitreous surgery.
[Mh] Termos MeSH primário: Triancinolona Acetonida/química
[Mh] Termos MeSH secundário: Fenômenos Químicos
Glucocorticoides
Seres Humanos
Microscopia Eletroquímica de Varredura
Tamanho da Partícula
Polissorbatos
Tensoativos
Triancinolona Acetonida/classificação
Vitrectomia/métodos
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Glucocorticoids); 0 (Polysorbates); 0 (Surface-Active Agents); F446C597KA (Triamcinolone Acetonide)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171005
[Lr] Data última revisão:
171005
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170707
[St] Status:MEDLINE


  3 / 210 MEDLINE  
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[PMID]:28626138
[Au] Autor:Haq AU; Saeed M; Anjum S; Bokhari TH; Usman M; Tubbsum S
[Ad] Endereço:Department of Chemistry, Government College University Faisalabad.
[Ti] Título:Evaluation of Sorption Mechanism of Pb (II) and Ni (II) onto Pea (Pisum sativum) Peels.
[So] Source:J Oleo Sci;66(7):735-743, 2017 Jul 01.
[Is] ISSN:1347-3352
[Cp] País de publicação:Japan
[La] Idioma:eng
[Ab] Resumo:The present study was carried out to know the sorption mechanism of Pb (II) and Ni (II) in aqueous solution using pea peels under the influence of sorbent dose, pH, temperature, initial metal ion concentration and contact time. SEM and FTIR were used for characterization of pea peels. The study showed that solution pH affects sorption process and the optimum pH for Pb (II) was 6.0 while for that of Ni (II) was 7.0. Pseudo-second order kinetic model was found to be the most suitable one to explain the kinetic data not only due to high value of R (>0.99) but also due to the closeness of the experimental sorption capacity values to that of calculated sorption capacity values of pseudo second order kinetic model. It can be seen from the results that Freundlich isotherm explains well the equilibrium data (R >0.99). Sorption capacity of pea peels was 140.84 and 32.36 for Pb (II) and Ni (II) mg g respectively. The positive value of ΔH° and negative values of ΔG° suggest that sorption of Pb (II) and Ni (II) onto pea peels is an endothermic and spontaneous process respectively.
[Mh] Termos MeSH primário: Poluentes Ambientais/isolamento & purificação
Resíduos Industriais
Chumbo/isolamento & purificação
Níquel/isolamento & purificação
Ervilhas
[Mh] Termos MeSH secundário: Adsorção
Concentração de Íons de Hidrogênio
Microscopia Eletroquímica de Varredura
Ervilhas/ultraestrutura
Soluções
Temperatura Ambiente
Termodinâmica
Fatores de Tempo
Água
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Environmental Pollutants); 0 (Industrial Waste); 0 (Solutions); 059QF0KO0R (Water); 2P299V784P (Lead); 7OV03QG267 (Nickel)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170620
[St] Status:MEDLINE
[do] DOI:10.5650/jos.ess17020


  4 / 210 MEDLINE  
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[PMID]:28399288
[Au] Autor:Dufek MI; Mulieri PR
[Ad] Endereço:Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Universidad Nacional del Nordeste, Facultad de Ciencias Exactas y Naturales y Agrimensura, Biología de los Artrópodos, Libertad St. 5470, Corrientes, Argentina.
[Ti] Título:Two New Species of Oxysarcodexia Townsend (Diptera: Sarcophagidae) From the Chaco Forest Ecoregion of South America.
[So] Source:J Med Entomol;54(4):917-924, 2017 Jul 01.
[Is] ISSN:1938-2928
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Two new Neotropical species of the genus Oxysarcodexia Townsend (Diptera: Sarcophagidae) from Chaco ecoregion of Argentina are described, O. berthet, sp. nov. and O. ibera, sp. nov. Both species were recovered from localities in the eastern part of the Chaco forest (Humid Chaco). The descriptions are based on the male external morphology and terminalia. Photographs and SEM images are provided to aid in the identification of the species.
[Mh] Termos MeSH primário: Distribuição Animal
Sarcofagídeos/anatomia & histologia
Sarcofagídeos/classificação
[Mh] Termos MeSH secundário: Animais
Argentina
Genitália Masculina/anatomia & histologia
Genitália Masculina/ultraestrutura
Masculino
Microscopia Eletroquímica de Varredura
Sarcofagídeos/fisiologia
Sarcofagídeos/ultraestrutura
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171013
[Lr] Data última revisão:
171013
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.1093/jme/tjx054


  5 / 210 MEDLINE  
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[PMID]:28342743
[Au] Autor:Zajac M; Dolowy K
[Ad] Endereço:Department of Biophysics, Warsaw University of Life Sciences - SGGW, Nowoursynowska 159, 02-776 Warsaw, Poland.
[Ti] Título:Measurement of ion fluxes across epithelia.
[So] Source:Prog Biophys Mol Biol;127:1-11, 2017 Aug.
[Is] ISSN:1873-1732
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Epithelial tissues line all wet surfaces of vertebrate bodies. Their major function is directional transport of ions and water. Cells forming an epithelial layer are bound together by a tight junction that forms a barrier to ion flux. Ions and water are transported via specialized molecules. The presence of a defect in a single ion channel molecule leads to cystic fibrosis - the most common, fatal, human genetic disease. The paper describes ion transport data obtained by means of different experimental techniques. Special attention is given to radiochemical tracers, transepithelial resistance determination, open circuit potential and short circuit current measurements, the nasal potential difference in healthy and cystic fibrosis patients, the use of ion selective electrodes, and electrochemical mapping of the cell membrane surface. The effect of different activators and blockers of ion transport molecules on measured parameters are also discussed.
[Mh] Termos MeSH primário: Epitélio/metabolismo
[Mh] Termos MeSH secundário: Animais
Transporte Biológico
Fibrose Cística/metabolismo
Fibrose Cística/patologia
Seres Humanos
Íons/metabolismo
Microscopia Eletroquímica de Varredura
Traçadores Radioativos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Ions); 0 (Radioactive Tracers)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170904
[Lr] Data última revisão:
170904
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170327
[St] Status:MEDLINE


  6 / 210 MEDLINE  
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[PMID]:28276318
[Au] Autor:Long DD; Wang Q; Han JR
[Ti] Título:Biosorption of Copper (II) from Aqueous Solutions by Sclerotiogenic G15.
[So] Source:Water Environ Res;89(8):703-713, 2017 Aug 01.
[Is] ISSN:1061-4303
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study aimed at investigating the biosorption of copper(II) from aqueous solutions by sclerotiogenic Aspergillus oryzae G15. Potentiometric titration analysis results indicated that carboxyl group was mainly responsible for Cu(II) adsorption. Sclerotia were a better biosorbent than mycelia, which could be ascribed to the higher amount of carboxyl sites exposed after differentiation. Langmuir isotherm model fitted well the absorption process of mycelia and sclerotia with the maximum theoretical sorption capacities of 35.34 and 73.53 mg/g, respectively. Scanning electron microscopy coupled with energy dispersive X-ray analysis confirmed that there was surface biosorption of Cu(II) on the adsorbents. Based on the fourier transform infrared spectroscopy analyses results, it could be proposed that the increased sorption capacity of sclerotia was due to increased functional groups related to the biosorption process. Cu(II)-loaded biosorbents could be regenerated and reused, which indicated that A. oryzae G15 could be considered as an alternative for removing Cu(II) from wastewater.
[Mh] Termos MeSH primário: Aspergillus oryzae/metabolismo
Cobre/metabolismo
[Mh] Termos MeSH secundário: Adsorção
Cobre/química
Concentração de Íons de Hidrogênio
Microscopia Eletroquímica de Varredura
Poluentes Químicos da Água/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Water Pollutants, Chemical); 789U1901C5 (Copper)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170925
[Lr] Data última revisão:
170925
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170310
[St] Status:MEDLINE
[do] DOI:10.2175/106143017X14839994523749


  7 / 210 MEDLINE  
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[PMID]:28258580
[Au] Autor:Solenov EI; Baturina GS; Katkova LE; Zarogiannis SG
[Ad] Endereço:Institute of Cytology and Genetics, SB RAS, 630090, Novosibirsk, Russia. eugsol@bionet.nsc.ru.
[Ti] Título:Methods to Measure Water Permeability.
[So] Source:Adv Exp Med Biol;969:263-276, 2017.
[Is] ISSN:0065-2598
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Water permeability is a key feature of the cell plasma membranes and it has seminal importance for a number of cell functions such as cell volume regulation, cell proliferation, cell migration, and angiogenesis to name a few. The transport of water occurs mainly through plasma membrane water channels , the aquaporins, who have very important function in physiological and pathophysiological states. Due to the above the experimental assessment of the water permeability of cells and tissues is necessary. The development of new methodologies of measuring water permeability is a vibrant scientific field that constantly develops during the past three decades along with the advances in imaging mainly. In this chapter we describe and critically assess several methods that have been developed for the measurement of water permeability both in living cells as well as in tissues with a focus in the first category.
[Mh] Termos MeSH primário: Aquaporinas/metabolismo
Microscopia de Força Atômica/métodos
Microscopia Eletroquímica de Varredura/métodos
Microscopia de Varredura por Sonda/métodos
Imagem Molecular/métodos
Água/metabolismo
[Mh] Termos MeSH secundário: Animais
Aquaporinas/genética
Membrana Celular/metabolismo
Permeabilidade da Membrana Celular
Movimento Celular
Proliferação Celular
Cães
Impedância Elétrica
Expressão Gênica
Seres Humanos
Células Madin Darby de Rim Canino
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Aquaporins); 059QF0KO0R (Water)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170907
[Lr] Data última revisão:
170907
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170305
[St] Status:MEDLINE
[do] DOI:10.1007/978-94-024-1057-0_18


  8 / 210 MEDLINE  
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[PMID]:28095525
[Au] Autor:Weng CC; Ou KL; Wu CY; Huang YH; Wang J; Yen Y; Cheng HY; Lin YH
[Ti] Título:Mechanism and Clinical Properties of StemBios Cell Therapy: Induction of Early Osseointegration in Novel Dental Implants.
[So] Source:Int J Oral Maxillofac Implants;32(1):e47-e54, 2017 Jan/Feb.
[Is] ISSN:1942-4434
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:PURPOSE: To examine early bone tissue healing in dental implants incorporating StemBios cell therapy. MATERIALS AND METHODS: SLAffinity samples were examined by scanning electron microscopy and atomic force microscopy. The clinical trial comprised 11 patients, who each received a dental implant in the mandible. Only one of these 11 patients received StemBios cell therapy in combination with the dental implant. The patients continued to be observed over a 4-month period after implantation using computed tomography and resonance frequency analysis. RESULTS: It was found that StemBios cell therapy promoted bone tissue healing in the case of the treated dental implant. The data indicated that stress altered more smoothly and declined faster in the patient who received the StemBios cell therapy than those without StemBios cell therapy over 4 months. CONCLUSION: A dental implant with SLAffinity surface treatment, in combination with StemBios cell therapy, significantly promoted bone tissue healing, especially at early osseointegration compared with that of implants without StemBios cell therapy when monitored over a 4-month period.
[Mh] Termos MeSH primário: Implantação Dentária Endo-Óssea/métodos
Implantes Dentários
Osseointegração/fisiologia
Transplante de Células-Tronco/métodos
[Mh] Termos MeSH secundário: Adulto
Planejamento de Prótese Dentária
Feminino
Seres Humanos
Masculino
Mandíbula/cirurgia
Microscopia Eletroquímica de Varredura
Meia-Idade
Propriedades de Superfície
Titânio
Cicatrização/fisiologia
[Pt] Tipo de publicação:CLINICAL TRIAL; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Dental Implants); D1JT611TNE (Titanium)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:D; IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE
[do] DOI:10.11607/jomi.4460


  9 / 210 MEDLINE  
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[PMID]:28095333
[Au] Autor:Bonechi C; Lamponi S; Donati A; Tamasi G; Consumi M; Leone G; Rossi C; Magnani A
[Ad] Endereço:Department of Biotechnologies, Chemistry, and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy; CSGI-Research Center for Colloids and Nanoscience, Via della Lastruccia 3, 50019 Sesto Fiorentino, FI, Italy. Electronic address: claudia.bonechi@unisi.it.
[Ti] Título:Effect of resveratrol on platelet aggregation by fibrinogen protection.
[So] Source:Biophys Chem;222:41-48, 2017 Mar.
[Is] ISSN:1873-4200
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The effect of resveratrol (RSV) in inhibiting platelet adhesion and aggregation, as well as fibrinogen (FBG) conformational changes promoted by epinephrine (EP), were studied, by using complementary experimental techniques. NMR and IR spectroscopies were used to investigate possible protective effects by RSV towards FBG, in presence of EP. The protective effect of RSV towards FBG was highlighted by spin nuclear relaxation experiments that were interpreted for determining the thermodynamic equilibrium constants of FBG-EP interaction, and by infrared measurements, that showed EP-induced conformational changes of FBG. The ability of RSV in inhibiting platelet adhesion and aggregation promoted by EP was evaluated by scanning electron microscopy (SEM), measuring the platelet adhesion and aggregation degree, in comparison to data obtained for platelet aggregation in platelet rich plasma (PRP). The experimental combined approach pointed out that RSV is able to protect both FBG and platelets from the denaturant and aggregating action of EP at stress level concentration.
[Mh] Termos MeSH primário: Fibrinogênio/química
Agregação Plaquetária/efeitos dos fármacos
Estilbenos/farmacologia
[Mh] Termos MeSH secundário: Epinefrina/farmacologia
Fibrinogênio/efeitos dos fármacos
Fibrinogênio/ultraestrutura
Seres Humanos
Microscopia Eletroquímica de Varredura
Substâncias Protetoras/farmacologia
Conformação Proteica/efeitos dos fármacos
Análise Espectral
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Protective Agents); 0 (Stilbenes); 9001-32-5 (Fibrinogen); Q369O8926L (resveratrol); YKH834O4BH (Epinephrine)
[Em] Mês de entrada:1705
[Cu] Atualização por classe:170503
[Lr] Data última revisão:
170503
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170118
[St] Status:MEDLINE


  10 / 210 MEDLINE  
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[PMID]:28064093
[Au] Autor:Romio M; Mesa C
[Ad] Endereço:Dept. of Chemistry, La Sapienza University, P.le A. Moro 5, 00185, Rome, Italy.
[Ti] Título:Hybrid nano-composites made of ss-DNA/wrapped carbon nanotubes and titania.
[So] Source:Colloids Surf B Biointerfaces;152:12-17, 2017 Apr 01.
[Is] ISSN:1873-4367
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Multi-walled carbon nanotubes, MWCNTs, are stabilized thanks to the surface wrapping of single-strand DNA, ss-DNA; the resulting adducts are kinetically and thermodynamically stable Such entities build up nano-hybrids with titania, TiO , nano-particles, in presence of surfactant as an adjuvant. The conditions leading to TiO adsorption onto ss-DNA/CNTs were investigated, by optimizing the concentration of adducts, nano-particles (NPs), and of the cationic surfactant (CTAB). Controlling the working conditions makes possible to get homogeneously organized hybrids. Characterization by DLS, electro-phoretic mobility, SEM and AFM clarified the surfactant-assisted association modes between adducts and CTAB-functionalized TiO . Nano-particles' clustering onto DNA-wrapped adducts gives hybrids trough electrostatic interactions. Surface coverage by TiO is significant and homogeneous. It is expected that the reported hybrids can be useful for applications in heterogeneous catalysis.
[Mh] Termos MeSH primário: DNA de Cadeia Simples/química
Nanocompostos/química
Nanotubos de Carbono/química
Titânio/química
[Mh] Termos MeSH secundário: DNA de Cadeia Simples/ultraestrutura
Cinética
Microscopia de Força Atômica
Microscopia Eletroquímica de Varredura
Nanocompostos/ultraestrutura
Nanotubos de Carbono/ultraestrutura
Tensoativos/química
Termodinâmica
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (DNA, Single-Stranded); 0 (Nanotubes, Carbon); 0 (Surface-Active Agents); 15FIX9V2JP (titanium dioxide); D1JT611TNE (Titanium)
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170321
[Lr] Data última revisão:
170321
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170109
[St] Status:MEDLINE



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