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| [PMID]: | 28168899 |
| [Au] Autor: | McMullen KP; Lin C; Harris MS; Adunka OF |
| [Ad] Endereço: | 1 Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA. |
| [Ti] Título: | Correlation of Objective Audiometric and Caloric Function in Ménière's Disease. |
| [So] Source: | Otolaryngol Head Neck Surg;156(5):912-916, 2017 May. | | [Is] ISSN: | 1097-6817 |
| [Cp] País de publicação: | England |
| [La] Idioma: | eng |
| [Ab] Resumo: | Objective Ménière's disease affects the vestibular and audiologic systems; however, little is known about the relationship between audiometric and caloric function with increasing duration of disease. We employed a novel methodology to understand the longitudinal correlation between audiometric and caloric function in Ménière's patients. Study Design Case series with chart review. Setting Neuro-otologic tertiary care practice. Subjects and Methods Charts of 19 patients with unilateral Ménière's disease, as classified by the 1995 American Academy of Otolaryngology-Head and Neck Foundation criteria, were examined. We included patients with ≥2 videonystagmograms and audiograms. We excluded those with bilateral Ménière's, prior audiovestibular destruction, or symptoms suggesting concomitant vestibular pathology. Spearman's rank correlation of audiometric status (pure tone average [PTA], low PTA, and word recognition score [WRS]) and vestibular function (bithermal calorics) was performed. The study was Institutional Review Board approved (protocol 2015H0266). Results A total of 112 audiograms and 42 videonystagmographies were performed. There was a decline in affected ear hearing PTA and WRS with duration of disease ( r = 0.602, P < .001, and r = -0.573, P < .001, respectively). Similarly, there was a decline in vestibular function with increasing duration of disease ( r = 0.709, P < .001). There were moderate correlations between vestibular weakness and PTA, low PTA, and WRS ( r = 0.464, P = .002; r = 0.498, P = .001; and r = -0.518, P = .001, respectively). Conclusions There is a correlation between decline in objective hearing and horizontal semicircular canal function with time. As expected, this correlation is not 1:1, indicating differential involvement of both systems. Understanding this relationship may assist in counseling patients with regard to prognosis, natural history, and therapeutic interventions. |
| [Mh] Termos MeSH primário: |
Audiometria de Resposta Evocada/métodos
Testes Calóricos/métodos
Doença de Meniere/diagnóstico
Potenciais Evocados Miogênicos Vestibulares/fisiologia
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| [Mh] Termos MeSH secundário: |
Adulto
Fatores Etários
Idoso
Audiometria/métodos
Estudos de Coortes
Bases de Dados Factuais
Progressão da Doença
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Medição de Risco
Sensibilidade e Especificidade
Índice de Gravidade de Doença
Fatores Sexuais
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| [Pt] Tipo de publicação: | COMPARATIVE STUDY; JOURNAL ARTICLE |
| [Em] Mês de entrada: | 1708 |
| [Cu] Atualização por classe: | 170816 |
[Lr] Data última revisão:
| 170816 |
| [Sb] Subgrupo de revista: | IM |
| [Da] Data de entrada para processamento: | 170208 |
| [St] Status: | MEDLINE |
| [do] DOI: | 10.1177/0194599817690103 |
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