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  1 / 1870 MEDLINE  
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[PMID]:29190293
[Au] Autor:Choi JE; Kim YK; Cho YS; Lee K; Park HW; Yoon SH; Kim HJ; Chung WH
[Ad] Endereço:Department of Otorhinolaryngology-Head and Neck Surgery, Dankook University Hospital, Cheonan, Republic of Korea.
[Ti] Título:Morphological correlation between caloric tests and vestibular hydrops in Ménière's disease using intravenous Gd enhanced inner ear MRI.
[So] Source:PLoS One;12(11):e0188301, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The purpose of this study was to prove the hypothesis that caloric response in Ménière's disease (MD) is reduced by hydropic expansion of the vestibular labyrinth, not by vestibular hypofunction, by evaluating the correlation morphologically using an intravenous Gadolinium (IV-Gd) inner ear MRI. In study I, the prevalence of abnormal video Head Impulse Test (vHIT) results among the patients with definite unilateral MD (n = 24) and vestibular neuritis (VN) (n = 22) were investigated. All patients showed abnormal canal paresis (CP) (> 26%) on caloric tests. The prevalence of abnormal vHIT in patients with abnormal CP was significantly lower in MD patients (12.5%) than that in VN patients (81.8%) (p < 0.001). In study II, morphological correlation between caloric tests and vestibular hydrops level was evaluated in unilateral MD patients (n = 16) who had normal vHIT results. Eleven patients (61%) had abnormal CP. After taking the images of IV-Gd inner ear MRI, the vestibular hydrops ratio (endolymph volume/total lymph volume = %VH) was measured. In addition, the relative vestibular hydrops ratio (%RVH = (%VHaffected ear-%VHunaffected ear) / (%VHaffected ear + %VHunaffected ear)) was calculated. Each ratio (%VH and %RVH) was compared with average peak slow phase velocity (PSPV) and CP, respectively. In the MD patients, %VH of the affected ear correlated significantly with mean PSPV on the same side (rs = -0.569, p = 0.024), while %RVH correlated significantly with CP (rs = 0.602, p = 0.014). In most MD patients (87.5%) compared to VN patients, vHIT results were normal even though the caloric function was reduced. In addition, the reduced caloric function with normal vHIT was related to the severity of the vestibular hydrops measured by the IV-Gd inner ear MRI. These findings concluded that the abnormal caloric tests with normal vHIT in MD indicated severe endolymphatic hydrops rather than vestibular hypofunction.
[Mh] Termos MeSH primário: Testes Calóricos
Gadolínio/administração & dosagem
Imagem por Ressonância Magnética/métodos
Doença de Meniere/fisiopatologia
Vestíbulo do Labirinto/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Masculino
Meia-Idade
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
AU0V1LM3JT (Gadolinium)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171226
[Lr] Data última revisão:
171226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188301


  2 / 1870 MEDLINE  
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[PMID]:28745751
[Au] Autor:Thompson BR; Horozov TS; Stoyanov SD; Paunov VN
[Ad] Endereço:School of Mathematics and Physical Sciences (Chemistry), University of Hull, Hull, UK. V.N.Paunov@hull.ac.uk.
[Ti] Título:Structuring and calorie control of bakery products by templating batter with ultra melt-resistant food-grade hydrogel beads.
[So] Source:Food Funct;8(8):2967-2973, 2017 Aug 01.
[Is] ISSN:2042-650X
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:We report the use of a temperature insensitive, food-grade hydrogel to reduce the caloric density of pancakes that were prepared at temperatures much higher than the boiling point of water. This cheap, facile method utilises a mixed agar-methylcellulose hydrogel, which was blended to produce a slurry of hydrogel microbeads. The pancake batter was mixed with a controlled volume percentage of slurry of hydrogel beads and cooked. From bomb calorimetry experiments, the composites were found to have a reduced caloric density that reflects the volume percentage of hydrogel beads mixed with the batter. Using this procedure, we were able to reduce the caloric density of pancakes by up to 23 ± 3% when the volume percentage of hydrogel beads initially used was 25%. The method is not limited to pancakes and could potentially be applied to various other food products. The structure and morphology of the freeze-dried pancakes and pancake-hydrogel composites were investigated and pores of a similar size to the hydrogel beads were found, confirming that the gel beads maintained their structure during the cooking process. There is scope for further development of this method by the encapsulation of nutritionally beneficial or flavour enhancing ingredients within the hydrogel beads.
[Mh] Termos MeSH primário: Aditivos Alimentares/química
Hidrogel de Polietilenoglicol-Dimetacrilato/química
[Mh] Termos MeSH secundário: Testes Calóricos
Culinária
Farinha/análise
Análise de Alimentos
Temperatura Alta
Metilcelulose/química
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Food Additives); 25852-47-5 (Hydrogel, Polyethylene Glycol Dimethacrylate); 9004-67-5 (Methylcellulose)
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171215
[Lr] Data última revisão:
171215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1039/c7fo00867h


  3 / 1870 MEDLINE  
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[PMID]:28954005
[Au] Autor:Mezzalira R; Bittar RSM; do Carmo Bilécki-Stipsky MM; Brugnera C; Grasel SS
[Ad] Endereço:Departamento de Otorrinolaringologia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.
[Ti] Título:Sensitivity of caloric test and video head impulse as screening test for chronic vestibular complaints.
[So] Source:Clinics (Sao Paulo);72(8):469-473, 2017 Aug.
[Is] ISSN:1980-5322
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE:: This study compared the results of the caloric test with those of the video head impulse test obtained during the same session and evaluated whether the former can be used to screen for non-acute vestibular dysfunction. METHODS:: A total of 157 participants complaining of dizziness with vestibular characteristics of varying durations and clinical courses completed the caloric test and video head impulse test. RESULTS:: Significantly more caloric test results than video head impulse test results were abnormal. CONCLUSIONS:: The results of the caloric test and video head impulse test are distinct but complement each other. Within our sample, the caloric test was more sensitive for vestibular dysfunction. Therefore, the video head impulse test is not a suitable screening tool of the vestibular system in patients with chronic complaints.
[Mh] Termos MeSH primário: Testes Calóricos/métodos
Tontura/diagnóstico
Tontura/fisiopatologia
Teste do Impulso da Cabeça/métodos
Doenças Vestibulares/diagnóstico
Doenças Vestibulares/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Doença Crônica
Estudos Transversais
Feminino
Seres Humanos
Masculino
Programas de Rastreamento
Meia-Idade
Valores de Referência
Reprodutibilidade dos Testes
Canais Semicirculares/fisiopatologia
Gravação em Vídeo
[Pt] Tipo de publicação:COMPARATIVE STUDY; EVALUATION STUDIES; JOURNAL ARTICLE; MULTICENTER STUDY
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171016
[Lr] Data última revisão:
171016
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


  4 / 1870 MEDLINE  
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[PMID]:28436247
[Au] Autor:Nishi T; Kamogashira T; Fujimoto C; Kinoshita M; Egami N; Sugasawa K; Yamasoba T; Iwasaki S
[Ad] Endereço:1 Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
[Ti] Título:Effects of Peripheral Vestibular Dysfunction on Dynamic Postural Stability Measured by the Functional Reach Test and Timed Up and Go Test.
[So] Source:Ann Otol Rhinol Laryngol;126(6):438-444, 2017 Jun.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To investigate the influence of vestibular function on dynamic postural stability assessed by the functional reach test (FRT) and the timed up and go test (TUG). STUDY DESIGN: Retrospective study. SETTING: Tertiary referral center. SUBJECTS AND METHODS: The FRT and TUG were performed in 399 patients with dizziness. The effects of peripheral vestibular dysfunction assessed by the caloric test and cervical vestibular evoked myogenic potentials (cVEMPs) to air-conducted sound (500 Hz, tone burst) on the results of FRT and TUG were analyzed. RESULTS: Neither FRT nor TUG scores showed significant differences in relation to the results of the caloric test ( P > .3). The FRT scores in patients who showed abnormal cVEMP responses on both sides were significantly smaller than those in patients who showed normal cVEMP responses ( P < .01). The TUG scores in patients who showed abnormal cVEMP responses on both sides were significantly greater than those in patients who showed normal cVEMP responses ( P < .05). CONCLUSION: The vestibulo-spinal reflex mediated by the saccule and its afferents is one of the factors that influence the maintenance of dynamic postural stability as measured by FRT and TUG.
[Mh] Termos MeSH primário: Teste de Esforço/métodos
Postura/fisiologia
Vestíbulo do Labirinto/fisiopatologia
[Mh] Termos MeSH secundário: Testes Calóricos
Tontura/etiologia
Tontura/fisiopatologia
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Potenciais Evocados Miogênicos Vestibulares/fisiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1707
[Cu] Atualização por classe:170713
[Lr] Data última revisão:
170713
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417700439


  5 / 1870 MEDLINE  
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[PMID]:28397037
[Au] Autor:Liu J; Zhou RH; Liu B; Leng YM; Liu JJ; Liu DD; Zhang SL; Kong WJ
[Ad] Endereço:Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
[Ti] Título:Assessment of balance and vestibular functions in patients with idiopathic sudden sensorineural hearing loss.
[So] Source:J Huazhong Univ Sci Technolog Med Sci;37(2):264-270, 2017 Apr.
[Is] ISSN:1672-0733
[Cp] País de publicação:China
[La] Idioma:eng
[Ab] Resumo:This study investigated the relationship among the severity of hearing impairment, vestibular function and balance function in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). A total of 35 ISSNHL patients (including 21 patients with vertigo) were enrolled. All of the patients underwent audiometry, sensory organization test (SOT), caloric test, cervical vestibular-evoked myogenic potential (cVEMP) test and ocular vestibular-evoked myogenic potential (oVEMP) test. Significant relationship was found between vertigo and hearing loss grade (P=0.009), and between SOT VEST grade and hearing loss grade (P=0.001). The abnormal rate of oVEMP test was the highest, followed by the abnormal rates of caloric and cVEMP tests, not only in patients with vertigo but also in those without vertigo. The vestibular end organs were more susceptible to damage in patients with vertigo (compared with patients without vertigo). Significant relationship was found between presence of vertigo and SOT VEST grade (P=0.010). We demonstrated that vestibular end organs may be impaired not only in patients with vertigo but also in patients without vertigo. The cochlear and vestibular impairment could be more serious in patients with vertigo than in those without vertigo. Vertigo does not necessarily bear a causal relationship with the impairment of the vestibular end organs. SOT VEST grade could be used to reflect the presence of vertigo state in the ISSNHL patients. Apart from audiometry, the function of peripheral vestibular end organs and balance function should be evaluated to comprehensively understand ISSNHL. Better assessment of the condition will help us in clinical diagnosis, treatment and prognosis evaluation of ISSNHL.
[Mh] Termos MeSH primário: Perda Auditiva Súbita/fisiopatologia
Vertigem/fisiopatologia
Vestíbulo do Labirinto/fisiopatologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Audiometria de Tons Puros
Testes Calóricos
Feminino
Perda Auditiva Súbita/complicações
Seres Humanos
Masculino
Meia-Idade
Potenciais Evocados Miogênicos Vestibulares
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1706
[Cu] Atualização por classe:171104
[Lr] Data última revisão:
171104
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.1007/s11596-017-1726-8


  6 / 1870 MEDLINE  
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[PMID]:28395491
[Au] Autor:Wang J; Zhou YJ; Yu J; Gu J
[Ad] Endereço:Department of Otorhinolaryngology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China.
[Ti] Título:[The significance of directional preponderance in the evaluation of vestibular function in patients with vertigo].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;52(3):200-204, 2017 Mar 07.
[Is] ISSN:1673-0860
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To analyze the relationship between directional preponderance (DP), spontaneous nystagmus(SN) and vestibular disorders, and to investigate the significance of DP in directing peripheral vestibular function in patients with vertigo. This was a retrospective analysis of 394 cases diagnosed with peripheral vestibular disease accompanied by vertigo from March 2012 to June 2014 in the Outpatient Department of the Eye & ENT Hospital of Fudan University. Results of static and dynamic posture equilibrium tests, SN, unilateral weakness(UW), and DP in videonystagmography(VNG) were analyzed and compared. The mean interval time between the last vertigo attack and examination in patients with SN or DP in caloric test were 4.4 d and 7.3 d respectively, and those without SN or DP were 18.3 d and 17.5 d respectively. The patients were divided into two groups according to DP results of caloric test. DP-normal group had 203 cases and DP-abnormal group had 191 cases. Spontaneous nystagmus was presented in 44 cases in the DP-normal group (21.67%) and four in the DP-abnormal group (2.09%). A significant difference was found between the two groups (χ =35.27, =0.000). Deficiency of vestibular function was noted in 165 cases in the DP-normal group (81.28%) and 123 (64.40%) in the DP-abnormal group in static and dynamic posture equilibrium tests. The difference between the two groups was statistically significant (χ =14.26, =0.000). Compared with DP-normal patients, DP-abnormal patients are more likely to have spontaneous nystagmus and balance disorders due to vestibular dysfunction.
[Mh] Termos MeSH primário: Vertigem/fisiopatologia
Vestíbulo do Labirinto/fisiopatologia
[Mh] Termos MeSH secundário: Testes Calóricos
Feminino
Seres Humanos
Masculino
Nistagmo Patológico/fisiopatologia
Equilíbrio Postural/fisiologia
Estudos Retrospectivos
Fatores de Tempo
Vertigem/classificação
Doenças Vestibulares/fisiopatologia
Testes de Função Vestibular
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1673-0860.2017.03.007


  7 / 1870 MEDLINE  
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[PMID]:28395489
[Au] Autor:Xu KX; Chen TS; Wang W; Li SS; Liu Q; Wen C; Han X; Lin P
[Ad] Endereço:Department of Otorhinolaryngology Head and Neck Surgery, Tianjin First Center Hospital, Otorhinolaryngology Institute of Tianjin, Tianjin 300192, China.
[Ti] Título:[Frequency characteristics of the semicicular canals damage in patients with Meniere disease].
[So] Source:Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi;52(3):190-194, 2017 Mar 07.
[Is] ISSN:1673-0860
[Cp] País de publicação:China
[La] Idioma:chi
[Ab] Resumo:To evaluate semicircular canal damage and its frequency characteristics in Meniere disease patients. Sixty-seven Meniere disease patients accepted the video-head impulse test(vHIT)which responses to semicircular canal function of high frequency area, head shaking test(HST) which responses to semicircular canal function of middle frequency area, and caloric test(CT) which responses to semicircular canal function of low frequency area.Preferences were recorded including the video head impulse test gain (vHIT-G), head shaking nystagmus (HSN) and parameters of the unilateral weakness (UW) as observation index, and results of all the three tests were analyzed according to Meniere disease patients. SPSS 17.0 software was used to analyzed the data. The positive rate of CT, HSN and vHIT were 70.1%(47/67), 41.8%(28/67) and 23.9%(16/67) respectively. Comparation of the positive rate among CT, HST and vHIT showed statistically significant difference (χ =10.93, =0.001; χ =28.79, =0.000). Comparation of the positive rate between HST and vHIT showed statistically significant difference(χ =4.87, =0.027). Semicircular canal function damage in Meniere disease patients mainly presents in the low frequency area, which indicates a characteristic phenomenon that low-frequency function area (caloric test results) is more predisposed to be involved than that of middle-frequency function area (head shaking testing)and high-frequency function area (video head impulse testing) in Meniere disease patients.
[Mh] Termos MeSH primário: Teste do Impulso da Cabeça
Doença de Meniere/fisiopatologia
Canais Semicirculares/fisiopatologia
[Mh] Termos MeSH secundário: Testes Calóricos
Feminino
Seres Humanos
Masculino
Nistagmo Patológico/fisiopatologia
Software
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170803
[Lr] Data última revisão:
170803
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170412
[St] Status:MEDLINE
[do] DOI:10.3760/cma.j.issn.1673-0860.2017.03.005


  8 / 1870 MEDLINE  
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[PMID]:28290231
[Au] Autor:Gofrit SG; Mayler Y; Eliashar R; Bdolah-Abram T; Ilan O; Gross M
[Ad] Endereço:1 Hadassah-Hebrew University School of Medicine, Jerusalem, Israel.
[Ti] Título:The Association Between Vestibular Physical Examination, Vertigo Questionnaires, and the Electronystagmography in Patients With Vestibular Symptoms.
[So] Source:Ann Otol Rhinol Laryngol;126(4):315-321, 2017 Apr.
[Is] ISSN:1943-572X
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTS: Dizziness makes up a diagnostic and treatment challenge. The diagnostic accuracy of the medical history and vestibular physical examination in cases of vestibular symptoms is not clear. The aim of this study is to determine the association between vestibular physical examination, vestibular questionnaires, and electronystagmography (ENG) test in patients with vestibular symptoms. METHODS: This is a prospective study of 135 adults with vestibular symptoms. The subjects underwent targeted physical examination and filled vestibular questionnaires, including the Dizziness Handicap Inventory (DHI), before ENG testing. The results of the physical examination and questionnaires were compared with the final ENG findings. RESULTS: Of patients who had normal ENG results, 32.1% (17/52) showed abnormal physical examination, and 48.8% (40/82) of the patient who had normal physical examination showed abnormal ENG results ( P = .46). Among patients with severe disability by DHI, 46.4% (13/28) had an abnormal ENG, and 42.9% (12/28) had a normal ENG ( P = .39). CONCLUSIONS: This study did not demonstrate association between vestibular physical examination, vestibular questionnaires, and ENG results. Although history (augmented by questionnaires) and physical examination are the initial steps in the evaluation of vertigo, the current study suggests that they should be complemented by objective testing for evaluation of inner ear origin of vertigo.
[Mh] Termos MeSH primário: Eletronistagmografia
Exame Físico
Vertigem/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Vertigem Posicional Paroxística Benigna/diagnóstico
Vertigem Posicional Paroxística Benigna/fisiopatologia
Testes Calóricos
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Inquéritos e Questionários
Vertigem/fisiopatologia
Doenças Vestibulares/diagnóstico
Doenças Vestibulares/fisiopatologia
Testes de Função Vestibular
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1704
[Cu] Atualização por classe:170417
[Lr] Data última revisão:
170417
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170315
[St] Status:MEDLINE
[do] DOI:10.1177/0003489417691298


  9 / 1870 MEDLINE  
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[PMID]:28231364
[Au] Autor:Shih CP; Chou YC; Chen HC; Lee JC; Chu YH; Wang CH
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, #325, Section 2, Cheng-Kung Rd., Taipei 114, Taiwan. zhengping_shi@yahoo.com.tw.
[Ti] Título:Analysis of caloric test responses in sudden hearing loss.
[So] Source:Ear Nose Throat J;96(2):59-64, 2017 Feb.
[Is] ISSN:1942-7522
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Sudden sensorineural hearing loss is characterized by a rapid-onset hearing loss that develops within 3 days. Vertigo may also be present. We conducted a retrospective study to investigate whether the severity of a loss of caloric function is associated with the initial hearing loss and with hearing recovery. Our study population was made up of 135 patients-67 men and 68 women, aged 25 to 71 years (mean: 50.9)-with sudden sensorineural hearing loss who had undergone bithermal caloric testing. We compared various patient factors according to patients' hearing level and their response to caloric testing. We also analyzed the canal paresis (CP) value in patients with an abnormal caloric response according to three factors: disease severity, vertigo, and hearing recovery, and we evaluated the correlation between the loss of caloric function and hearing outcomes. We found that an abnormal caloric response was significantly associated with a profound hearing loss at presentation, the presence of vertigo, and poor hearing recovery. Among patients with an abnormal caloric response, the CP value was significantly correlated with hearing recovery (r = 0.503, p = 0.001). Poor hearing recovery was seen in 80% of patients with a CP value of ≥40% but in only 25% of patients with a value of <40%; in addition, the degree of hearing recovery was worse in the patients with a CP value of ≥40% (p = 0.002). We conclude that a CP value of ≥40% is a significant prognostic factor for an unfavorable treatment outcome.
[Mh] Termos MeSH primário: Testes Calóricos/métodos
Perda Auditiva Neurossensorial/fisiopatologia
Perda Auditiva Súbita/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Audição/fisiologia
Perda Auditiva Neurossensorial/complicações
Perda Auditiva Súbita/complicações
Seres Humanos
Masculino
Meia-Idade
Prognóstico
Recuperação de Função Fisiológica/fisiologia
Estudos Retrospectivos
Resultado do Tratamento
Vertigem/complicações
Vertigem/fisiopatologia
Vestíbulo do Labirinto/fisiopatologia
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171002
[Lr] Data última revisão:
171002
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170224
[St] Status:MEDLINE


  10 / 1870 MEDLINE  
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[PMID]:28168899
[Au] Autor:McMullen KP; Lin C; Harris MS; Adunka OF
[Ad] Endereço:1 Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, USA.
[Ti] Título:Correlation of Objective Audiometric and Caloric Function in Ménière's Disease.
[So] Source:Otolaryngol Head Neck Surg;156(5):912-916, 2017 May.
[Is] ISSN:1097-6817
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Objective Ménière's disease affects the vestibular and audiologic systems; however, little is known about the relationship between audiometric and caloric function with increasing duration of disease. We employed a novel methodology to understand the longitudinal correlation between audiometric and caloric function in Ménière's patients. Study Design Case series with chart review. Setting Neuro-otologic tertiary care practice. Subjects and Methods Charts of 19 patients with unilateral Ménière's disease, as classified by the 1995 American Academy of Otolaryngology-Head and Neck Foundation criteria, were examined. We included patients with ≥2 videonystagmograms and audiograms. We excluded those with bilateral Ménière's, prior audiovestibular destruction, or symptoms suggesting concomitant vestibular pathology. Spearman's rank correlation of audiometric status (pure tone average [PTA], low PTA, and word recognition score [WRS]) and vestibular function (bithermal calorics) was performed. The study was Institutional Review Board approved (protocol 2015H0266). Results A total of 112 audiograms and 42 videonystagmographies were performed. There was a decline in affected ear hearing PTA and WRS with duration of disease ( r = 0.602, P < .001, and r = -0.573, P < .001, respectively). Similarly, there was a decline in vestibular function with increasing duration of disease ( r = 0.709, P < .001). There were moderate correlations between vestibular weakness and PTA, low PTA, and WRS ( r = 0.464, P = .002; r = 0.498, P = .001; and r = -0.518, P = .001, respectively). Conclusions There is a correlation between decline in objective hearing and horizontal semicircular canal function with time. As expected, this correlation is not 1:1, indicating differential involvement of both systems. Understanding this relationship may assist in counseling patients with regard to prognosis, natural history, and therapeutic interventions.
[Mh] Termos MeSH primário: Audiometria de Resposta Evocada/métodos
Testes Calóricos/métodos
Doença de Meniere/diagnóstico
Potenciais Evocados Miogênicos Vestibulares/fisiologia
[Mh] Termos MeSH secundário: Adulto
Fatores Etários
Idoso
Audiometria/métodos
Estudos de Coortes
Bases de Dados Factuais
Progressão da Doença
Feminino
Seres Humanos
Masculino
Meia-Idade
Estudos Retrospectivos
Medição de Risco
Sensibilidade e Especificidade
Índice de Gravidade de Doença
Fatores Sexuais
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170816
[Lr] Data última revisão:
170816
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170208
[St] Status:MEDLINE
[do] DOI:10.1177/0194599817690103



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