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[PMID]:29203757
[Au] Autor:Osovska NY; Datsyuk OI; Kuzminova NV; Shaprynskyi YV; Bevz HV; Pashynskyy YM; Bondarchuk OD; Sergiichuk OV; Karyi YV; Mazur GM
[Ad] Endereço:National Pirogov Memorial Medical University, Vinnytsya, Ukraine.
[Ti] Título:Variant of myocardial infarction course in the patient with left ventricular non-compaction.
[So] Source:Wiad Lek;70(5):998-1004, 2017.
[Is] ISSN:0043-5147
[Cp] País de publicação:Poland
[La] Idioma:eng
[Ab] Resumo:Non-compacted left ventricle in adults is a rare occurrence, though it is diagnosed even more rarely. As a rule in patients with non-compacted left ventricle (LVNC) other pathologic condition is diagnosed, notably hypertrophic or dilated cardiomyopathy. The majority of LVNC cases are diagnosed in early infancy but currently there are asymptomatic cases detected by means of echocardiographic examination. Real prevalence of LVNC is unknown. According to many authors LVNC occurs in 9.2-9.5% of children with diagnosed cardiomyopathies. The majority of such children do not survive till adulthood because of progressive severe heart failure, fatal arrhythmias and thromboembolisms. This value ranges from 0.014 to 0.05% in adult population. The article presents a clinical case illustrating the stages in establishing the diagnosis of non-compacted left ventricle in a young patient with myocardial infarction and congestive heart failure. Common characteristics of non-compacted left ventricle and connective tissue dysplasia syndrome in the patient suggested etiopathogenetic relationship between these two pathologic states. The basic common characteristic feature of both non-compacted left ventricle and connective tissue dysplasia syndrome proved to be multiple abnormal chords of the left ventricle. The patient was supposed to have some coronary circulation abnormality inherited together with non-compacted left ventricle and connective tissue dysplasia syndrome. Adverse prognosis and high mortality in non-compacted left ventricle require its early recognition and differentiated approach to treatment depending on the severity of the disease and using all modern methods of treatment both conservative and surgical.
[Mh] Termos MeSH primário: Miocárdio Ventricular não Compactado Isolado/diagnóstico por imagem
Miocárdio Ventricular não Compactado Isolado/fisiopatologia
[Mh] Termos MeSH secundário: Adulto
Cardiomiopatia Dilatada/patologia
Criança
Ecocardiografia
Ventrículos do Coração/patologia
Seres Humanos
Anamnese
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180308
[Lr] Data última revisão:
180308
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171206
[St] Status:MEDLINE


  2 / 18075 MEDLINE  
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[PMID]:29292911
[Au] Autor:Bjurman C; Hammarsten O; Holzmann M
[Ad] Endereço:Medicinkliniken - Hallands Sjukhus Varberg, Sweden Medicinkliniken - Hallands Sjukhus Varberg, Sweden.
[Ti] Título:ABC om - Misstänkt kardiell bröstsmärta på akuten..
[So] Source:Lakartidningen;114, 2017 11 02.
[Is] ISSN:1652-7518
[Cp] País de publicação:Sweden
[La] Idioma:swe
[Mh] Termos MeSH primário: Dor no Peito/diagnóstico
Serviço Hospitalar de Emergência
[Mh] Termos MeSH secundário: Algoritmos
Diagnóstico Diferencial
Gerenciamento Clínico
Eletrocardiografia
Seres Humanos
Anamnese
Admissão do Paciente
Embolia Pulmonar/diagnóstico
Medição de Risco
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180301
[Lr] Data última revisão:
180301
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE


  3 / 18075 MEDLINE  
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[PMID]:29217517
[Au] Autor:Bould H; Newbegin C; Fazel M; Stewart A; Stein A
[Ad] Endereço:Department of Psychiatry, Warneford Hospital, Oxford, UK helen.bould@psych.ox.ac.uk.
[Ti] Título:Assessment of child or young person with a possible eating disorder.
[So] Source:BMJ;359:j5328, 2017 12 07.
[Is] ISSN:1756-1833
[Cp] País de publicação:England
[La] Idioma:eng
[Mh] Termos MeSH primário: Medicina de Família e Comunidade
Transtornos da Alimentação e da Ingestão de Alimentos/diagnóstico
[Mh] Termos MeSH secundário: Adolescente
Diagnóstico Diferencial
Transtornos da Alimentação e da Ingestão de Alimentos/terapia
Seres Humanos
Anamnese
Relações Médico-Paciente
Guias de Prática Clínica como Assunto
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171209
[St] Status:MEDLINE
[do] DOI:10.1136/bmj.j5328


  4 / 18075 MEDLINE  
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[PMID]:28470928
[Au] Autor:Ganzola R; Nickson T; Bastin ME; Giles S; Macdonald A; Sussmann J; McIntosh AM; Whalley HC; Duchesne S
[Ad] Endereço:Institut universitaire en santé mentale de Québec, Québec City, Québec, Canada.
[Ti] Título:Longitudinal differences in white matter integrity in youth at high familial risk for bipolar disorder.
[So] Source:Bipolar Disord;19(3):158-167, 2017 May.
[Is] ISSN:1399-5618
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Previous neuroimaging studies have reported abnormalities in white matter (WM) pathways in subjects at high familial risk of mood disorders. In the current study, we examined the trajectory of these abnormalities during the early stages of illness development using longitudinal diffusion tensor imaging (DTI) data. METHODS: Subjects (16-28 years old) were recruited in the Scottish Bipolar Family Study, a prospective longitudinal study that has examined individuals at familial risk of mood disorder on three occasions, 2 years apart. The current study concerns imaging data from the first and second assessments. We analysed DTI data for 43 controls and 69 high-risk individuals who were further subdivided into a group of 53 high-risk subjects who remained well (high-risk well) and 16 who met diagnostic criteria for major depressive disorder (high-risk MDD) at follow-up. Longitudinal differences in fractional anisotropy (FA) between groups based on diagnostic status were investigated using the tract-based spatial statistics technique (TBSS). RESULTS: We found a significant reduction in FA (P <.05) across widespread brain regions over 2 years in all three groups. The trajectory of FA reduction did not differ significantly between groups. CONCLUSIONS: These results suggest that there are similar trajectories of FA reductions for controls and high-risk young adults, despite high-risk individuals being at a disadvantaged starting point considering their reduced WM integrity detected at baseline in previous studies. Difference in WM integrity between high-risk individuals and controls could therefore occur in earlier childhood and be a necessary but not sufficient condition to develop future mood disorders.
[Mh] Termos MeSH primário: Transtorno Bipolar
Substância Branca/diagnóstico por imagem
[Mh] Termos MeSH secundário: Adolescente
Adulto
Anisotropia
Transtorno Bipolar/diagnóstico
Transtorno Bipolar/epidemiologia
Transtorno Depressivo Maior/diagnóstico
Transtorno Depressivo Maior/epidemiologia
Imagem de Tensor de Difusão/métodos
Feminino
Seres Humanos
Estudos Longitudinais
Masculino
Anamnese/métodos
Neuroimagem/métodos
Estudos Prospectivos
Medição de Risco
Fatores de Risco
Escócia/epidemiologia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180222
[Lr] Data última revisão:
180222
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170505
[St] Status:MEDLINE
[do] DOI:10.1111/bdi.12489


  5 / 18075 MEDLINE  
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[PMID]:29194159
[Au] Autor:Clark CA
[Ti] Título:Evaluating Nurse Practitioner Students Through Objective Structured Clinical Examination.
[So] Source:Nurs Educ Perspect;36(1):53-54, 2015 Jan/Feb.
[Is] ISSN:1536-5026
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:: Medical schools' use of Objective Structured Clinical Examination (OSCE) for over 30 years proves the OSCE is an objective way to assess a variety of clinical skills. This pilot study determined the feasibility of using OSCE, together with a checklist tool, to evaluate nurse practitioner (NP) students' competency in obtaining a patient's health history and performing a complete physical examination. In this descriptive study, four NP faculty viewed a prerecorded OSCE video of a student/ patient encounter and scored it using a checklist to determine the student's competency. Faculty showed a strong degree of agreement in grading competence. Findings suggest OSCEs could be an effective means of student evaluation, but revising the checklist to align with NP national competencies would make it meaningful for NP evaluation specifically.
[Mh] Termos MeSH primário: Competência Clínica/normas
Educação Baseada em Competências/normas
Avaliação Educacional/métodos
Anamnese/normas
Profissionais de Enfermagem/educação
Exame Físico/normas
[Mh] Termos MeSH secundário: Adulto
Lista de Checagem
Feminino
Seres Humanos
Masculino
Projetos Piloto
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:N
[Da] Data de entrada para processamento:171202
[St] Status:MEDLINE
[do] DOI:10.5480/13-1078.1


  6 / 18075 MEDLINE  
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[PMID]:29190838
[Au] Autor:Goldberg EM; McCreedy EM; Gettel CJ; Merchant RC
[Ad] Endereço:Assistant Professor of Emergency Medicine, Department of Emergency Medicine, Alpert Medical School of Brown University; Postdoctoral Research Fellow, Center of Gerontology and Healthcare Research,Brown University School of Public Health, Providence, RI.
[Ti] Título:Slipping through the cracks: A cross-sectional study examining older adult emergency department patient fall history, post-fall treatment and prevention.
[So] Source:R I Med J (2013);100(12):18-23, 2017 Dec 01.
[Is] ISSN:2327-2228
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Falls are the leading cause of emergency department (ED) visits for fatal and non-fatal injuries among adults 65 years old and older. We aimed to better understand the fall history, risk for further falls, and actions taken to prevent further falls among this higher fall risk population. This cross-sectional study included older adults without cognitive impairment presenting to the Rhode Island Hospital ED from February to May 2017. Of the 76 participants, 35 self-reported no prior falls, and 41 self-reported at least one prior fall, of whom 20 fell on the day of ED presentation. Participants with vs. without self-reported prior falls were similar in age, gender, race, and substance use. Participants with prior falls scored lower on cognitive testing and had more comorbidities associated with falls. Only one quarter of those with prior falls reported making changes and few were evaluated by professionals to prevent future falls. This study highlights that older adult ED patients who sustain a fall are at higher risk for subsequent falls, and that greater fall prevention efforts are needed to protect this vulnerable group. [Full article available at http://rimed.org/rimedicaljournal-2017-12.asp].
[Mh] Termos MeSH primário: Acidentes por Quedas/estatística & dados numéricos
Serviço Hospitalar de Emergência
Ferimentos e Lesões/etiologia
[Mh] Termos MeSH secundário: Acidentes por Quedas/prevenção & controle
Idoso
Idoso de 80 Anos ou mais
Estudos Transversais
Serviço Hospitalar de Emergência/normas
Serviço Hospitalar de Emergência/estatística & dados numéricos
Feminino
Avaliação Geriátrica
Seres Humanos
Masculino
Anamnese
Determinação de Necessidades de Cuidados de Saúde
Melhoria de Qualidade
Rhode Island/epidemiologia
Medição de Risco
Fatores de Risco
Prevenção Secundária
Autorrelato
Ferimentos e Lesões/diagnóstico
Ferimentos e Lesões/epidemiologia
Ferimentos e Lesões/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171201
[St] Status:MEDLINE


  7 / 18075 MEDLINE  
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[PMID]:29172409
[Au] Autor:Tigabu E; Bekele KB; Dachew BA
[Ad] Endereço:Ethiopian Paediatric Association, Amhara Region, Bahir Dar, Ethiopia.
[Ti] Título:Prevalence of goiter and associated factors among schoolchildren in northeast Ethiopia.
[So] Source:Epidemiol Health;39:e2017055, 2017.
[Is] ISSN:2092-7193
[Cp] País de publicação:Korea (South)
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: Goiter is a major public health problem, especially in developing countries such as Ethiopia. Hence, this study aimed to assess the prevalence and associated factors of goiter among children in Waghimra Zone, northeast Ethiopia. METHODS: A cross-sectional study was conducted from April 8 to 25, 2015 in northeast Ethiopia. A multistage sampling method was used to select 454 schoolchildren. Data were collected using a pre-tested structured interviewer-administered questionnaire. Children were examined for the presence or absence of goiter based on the criteria of the United Nations Children's Fund, International Council for the Control of Iodine Deficiency, and the World Health Organization. Salt samples from children's homes were tested for iodine levels using a rapid iodized salt test kit. Data were entered into EpiInfo version 7 and exported to SPSS version 20 for analysis. Bivariate and multivariate logistic regression models were fitted, and adjusted odds ratio (aOR) with 95% confidence interval (CI) were computed to determine the level of significance. RESULTS: The prevalence of goiter was 62.1% (95% CI, 57.5 to 66.5%). Being female (aOR, 3.09; 95% CI, 1.57 to 6.08), having a family history of goiter (aOR, 5.18; 95% CI, 2.43 to 11.03), and using non-iodized salt (aOR, 2.20; 95% CI, 1.12 to 4.38) were factors associated with goiter among schoolchildren. CONCLUSIONS: The prevalence of goiter was high. Being female and having a family history of goiter increased the risk of goiter in children, but using iodized salt was protective. Therefore, we recommend ensuring universal access to iodized salt and increasing the awareness of the community of the importance of iodized salt utilization.
[Mh] Termos MeSH primário: Bócio/epidemiologia
[Mh] Termos MeSH secundário: Criança
Estudos Transversais
Etiópia/epidemiologia
Feminino
Seres Humanos
Iodo/administração & dosagem
Masculino
Anamnese
Prevalência
Fatores de Risco
Distribuição por Sexo
Cloreto de Sódio na Dieta/administração & dosagem
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sodium Chloride, Dietary); 0 (iodized salt); 9679TC07X4 (Iodine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.4178/epih.e2017055


  8 / 18075 MEDLINE  
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[PMID]:29381936
[Au] Autor:Ye S; Dai T; Leng B; Tang L; Jin L; Cao L
[Ad] Endereço:Department of Neurology, Tianjin Huanhu Hospital.
[Ti] Título:Genotype and clinical course in 2 Chinese Han siblings with Wilson disease presenting with isolated disabling premature osteoarthritis: A case report.
[So] Source:Medicine (Baltimore);96(47):e8641, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Premature osteoarthritis (POA) is a rare condition in Wilson disease (WD). Particularly, when POA is the only complaint of a WD patient for a long time, there would be misdiagnosis or missed diagnosis and then treatment delay. PATIENT CONCERNS AND DIAGNOSIS: Two Chinese Han siblings were diagnosed as WD by corneal K-F rings, laboratory test, and mutation analysis. They presented with isolated POA during the first 2 decades or more of their disease course, and were of missed diagnosis during that long time. The older affected sib became disabled due to his severe osteoarthritis when he was as young as 38 years old. Two compound heterozygous pathogenic variants c.2790_2792del and c.2621C>T were revealed in the ATP7B gene through targeted next-generation sequencing (NGS). LESSONS: Adolescent-onset POA could be the only complaint of WD individual for at least 2 decades. Long delay in the treatment of WD's POA could lead to disability in early adulthood. Detailed physical examination, special biochemical test, and genotyping through targeted NGS should greatly reduce diagnosis delay in atypical WD patients with isolated POA phenotype.
[Mh] Termos MeSH primário: ATPases Transportadoras de Cobre/genética
Erros de Diagnóstico
Degeneração Hepatolenticular
Osteoartrite
Irmãos
Tempo para o Tratamento
[Mh] Termos MeSH secundário: Adulto
Idade de Início
China
Diagnóstico Tardio/efeitos adversos
Diagnóstico Tardio/prevenção & controle
Erros de Diagnóstico/efeitos adversos
Erros de Diagnóstico/prevenção & controle
Avaliação da Deficiência
Progressão da Doença
Degeneração Hepatolenticular/complicações
Degeneração Hepatolenticular/genética
Degeneração Hepatolenticular/fisiopatologia
Seres Humanos
Masculino
Anamnese
Mutação
Osteoartrite/diagnóstico
Osteoartrite/etiologia
Osteoartrite/fisiopatologia
Osteoartrite/prevenção & controle
Índice de Gravidade de Doença
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
EC 3.6.3.54 (ATP7B protein, human); EC 3.6.3.54 (Copper-transporting ATPases)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180208
[Lr] Data última revisão:
180208
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008641


  9 / 18075 MEDLINE  
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[PMID]:29237415
[Au] Autor:Beebe-Dimmer JL; Yee C; Paskett E; Schwartz AG; Lane D; Palmer NRA; Bock CH; Nassir R; Simon MS
[Ad] Endereço:Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, 48201, USA. dimmerj@karmanos.org.
[Ti] Título:Family history of prostate and colorectal cancer and risk of colorectal cancer in the Women's health initiative.
[So] Source:BMC Cancer;17(1):848, 2017 12 13.
[Is] ISSN:1471-2407
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Evidence suggests that risk of colorectal and prostate cancer is increased among those with a family history of the same disease, particularly among first-degree relatives. However, the aggregation of colorectal and prostate cancer within families has not been well investigated. METHODS: Analyses were conducted among participants of the Women's Health Initiative (WHI) observational cohort, free of cancer at the baseline examination. Subjects were followed for colorectal cancer through August 31st, 2009. A Cox-proportional hazards regression modeling approach was used to estimate risk of colorectal cancer associated with a family history of prostate cancer, colorectal cancer and both cancers among first-degree relatives of all participants and stratified by race (African American vs. White). RESULTS: Of 75,999 eligible participants, there were 1122 colorectal cancer cases diagnosed over the study period. A family history of prostate cancer alone was not associated with an increase in colorectal cancer risk after adjustment for confounders (aHR =0.94; 95% CI =0.76, 1.15). Separate analysis examining the joint impact, a family history of both colorectal and prostate cancer was associated with an almost 50% increase in colorectal cancer risk (aHR = 1.48; 95% CI = 1.04, 2.10), but similar to those with a family history of colorectal cancer only (95% CI = 1.31; 95% CI = 1.11, 1.54). CONCLUSIONS: Our findings suggest risk of colorectal cancer is increased similarly among women with colorectal cancer only and among those with both colorectal and prostate cancer diagnosed among first-degree family members. Future studies are needed to determine the relative contribution of genes and shared environment to the risk of both cancers.
[Mh] Termos MeSH primário: Neoplasias Colorretais/epidemiologia
Neoplasias Colorretais/genética
Anamnese
Neoplasias da Próstata/epidemiologia
Neoplasias da Próstata/genética
[Mh] Termos MeSH secundário: Idoso
Idoso de 80 Anos ou mais
Feminino
Seres Humanos
Masculino
Meia-Idade
Saúde da Mulher
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180202
[Lr] Data última revisão:
180202
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171215
[St] Status:MEDLINE
[do] DOI:10.1186/s12885-017-3873-5


  10 / 18075 MEDLINE  
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[PMID]:29362799
[Au] Autor:Patel JJ
[Ad] Endereço:Division of Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.
[Ti] Título:The Things We Say.
[So] Source:JAMA;319(4):341-342, 2018 Jan 23.
[Is] ISSN:1538-3598
[Cp] País de publicação:United States
[La] Idioma:eng
[Mh] Termos MeSH primário: Linguagem
Anamnese
Relações Médico-Paciente
[Mh] Termos MeSH secundário: Comunicação
Registros Eletrônicos de Saúde
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180131
[Lr] Data última revisão:
180131
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1001/jama.2017.20545



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