Base de dados : MEDLINE
Pesquisa : E02.037 [Categoria DeCS]
Referências encontradas : 39459 [refinar]
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[PMID]:29384606
[Au] Autor:Asaoka R; Gyoba J
[Ti] Título:Sounds Modulate the Perceived Duration of Visual Stimuli via Crossmodal Integration.
[So] Source:Multisens Res;29(4-5):319-35, 2016.
[Is] ISSN:2213-4794
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Previous studies have shown that the perceived duration of visual stimuli can be strongly distorted by auditory stimuli presented simultaneously. In this study, we examine whether sounds presented separately from target visual stimuli alter the perceived duration of the target's presentation. The participants' task was to classify the duration of the target visual stimuli as perceived by them into four categories. Our results demonstrate that a sound presented before and after a visual target increases or decreases the perceived visual duration depending on the inter-stimulus interval between the sounds and the visual stimulus. In addition, three tones presented before and after a visual target did not increase or decrease the perceived visual duration. This indicates that auditory perceptual grouping prevents intermodal perceptual grouping, and eliminates crossmodal effects. These findings suggest that the auditory­visual integration, rather than a high arousal state caused by the presentation of the preceding sound, can induce distortions of perceived visual duration, and that inter- and intramodal perceptual grouping plays an important role in crossmodal time perception. These findings are discussed with reference to the Scalar Expectancy Theory.
[Mh] Termos MeSH primário: Percepção Auditiva/fisiologia
Desempenho Psicomotor/fisiologia
Som
Percepção Visual/fisiologia
[Mh] Termos MeSH secundário: Estimulação Acústica
Adulto
Feminino
Seres Humanos
Masculino
Estimulação Luminosa
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180306
[Lr] Data última revisão:
180306
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE


  2 / 39459 MEDLINE  
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[PMID]:28451640
[Au] Autor:Horikawa J; Ojima H
[Ad] Endereço:Department of Computer Science and Engineering Graduate School of Engineering, Toyohashi University of Technology, Hibarigaoka 1-1, Tempaku, Toyohashi, Aichi 441-8580, Japan.
[Ti] Título:Cortical Activation Patterns Evoked by Temporally Asymmetric Sounds and Their Modulation by Learning.
[So] Source:eNeuro;4(2), 2017 Mar-Apr.
[Is] ISSN:2373-2822
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:When complex sounds are reversed in time, the original and reversed versions are perceived differently in spectral and temporal dimensions despite their identical duration and long-term spectrum-power profiles. Spatiotemporal activation patterns evoked by temporally asymmetric sound pairs demonstrate how the temporal envelope determines the readout of the spectrum. We examined the patterns of activation evoked by a temporally asymmetric sound pair in the primary auditory field (AI) of anesthetized guinea pigs and determined how discrimination training modified these patterns. Optical imaging using a voltage-sensitive dye revealed that a forward ramped-down natural sound (F) consistently evoked much stronger responses than its time-reversed, ramped-up counterpart (revF). The spatiotemporal maximum peak ( ) of F-evoked activation was always greater than that of revF-evoked activation, and these s were significantly separated within the AI. Although discrimination training did not affect the absolute magnitude of these s, the revF-to-F ratio of the activation peaks calculated at the location where hemispheres were maximally activated (i.e., F-evoked ) was significantly smaller in the trained group. The F-evoked activation propagated across the AI along the temporal axis to the ventroanterior belt field (VA), with the local activation peak within the VA being significantly larger in the trained than in the naïve group. These results suggest that the innate network is more responsive to natural sounds of ramped-down envelopes than their time-reversed, unnatural sounds. The VA belt field activation might play an important role in emotional learning of sounds through its connections with amygdala.
[Mh] Termos MeSH primário: Córtex Auditivo/fisiologia
Percepção Auditiva/fisiologia
Potenciais Evocados Auditivos
Aprendizagem
[Mh] Termos MeSH secundário: Estimulação Acústica
Animais
Discriminação (Psicologia)
Cobaias
Masculino
Imagem Óptica
Processamento de Sinais Assistido por Computador
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170429
[St] Status:MEDLINE


  3 / 39459 MEDLINE  
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[PMID]:27770624
[Au] Autor:Rocchi F; Dylla ME; Bohlen PA; Ramachandran R
[Ad] Endereço:Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN 37212, USA.
[Ti] Título:Spatial and temporal disparity in signals and maskers affects signal detection in non-human primates.
[So] Source:Hear Res;344:1-12, 2017 Feb.
[Is] ISSN:1878-5891
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:Detection thresholds for auditory stimuli (signals) increase in the presence of maskers. Natural environments contain maskers/distractors that can have a wide range of spatiotemporal properties relative to the signal. While these parameters have been well explored psychophysically in humans, they have not been well explored in animal models, and their neuronal underpinnings are not well understood. As a precursor to the neuronal measurements, we report the effects of systematically varying the spatial and temporal relationship between signals and noise in macaque monkeys (Macaca mulatta and Macaca radiata). Macaques detected tones masked by noise in a Go/No-Go task in which the spatiotemporal relationships between the tone and noise were systematically varied. Masked thresholds were higher when the masker was continuous or gated on and off simultaneously with the signal, and lower when the continuous masker was turned off during the signal. A burst of noise caused higher masked thresholds if it completely temporally overlapped with the signal, whereas partial overlap resulted in lower thresholds. Noise durations needed to be at least 100 ms before significant masking could be observed. Thresholds for short duration tones were significantly higher when the onsets of signal and masker coincided compared to when the signal was presented during the steady state portion of the noise (overshoot). When signal and masker were separated in space, masked signal detection thresholds decreased relative to when the masker and signal were co-located (spatial release from masking). Masking release was larger for azimuthal separations than for elevation separations. These results in macaques are similar to those observed in humans, suggesting that the specific spatiotemporal relationship between signal and masker determine threshold in natural environments for macaques in a manner similar to humans. These results form the basis for future investigations of neuronal correlates and mechanisms of masking.
[Mh] Termos MeSH primário: Comportamento Animal
Sinais (Psicologia)
Ruído/efeitos adversos
Mascaramento Perceptivo
Nível de Percepção Sonora
Detecção de Sinal Psicológico
Localização de Som
[Mh] Termos MeSH secundário: Estimulação Acústica
Animais
Audiometria
Vias Auditivas/fisiologia
Limiar Auditivo
Macaca mulatta
Macaca radiata
Masculino
Modelos Animais
Periodicidade
Psicoacústica
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161023
[St] Status:MEDLINE


  4 / 39459 MEDLINE  
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[PMID]:29385174
[Au] Autor:Kumeta M; Takahashi D; Takeyasu K; Yoshimura SH
[Ad] Endereço:Graduate School of Biostudies, Kyoto University, Kyoto, Japan.
[Ti] Título:Cell type-specific suppression of mechanosensitive genes by audible sound stimulation.
[So] Source:PLoS One;13(1):e0188764, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Audible sound is a ubiquitous environmental factor in nature that transmits oscillatory compressional pressure through the substances. To investigate the property of the sound as a mechanical stimulus for cells, an experimental system was set up using 94.0 dB sound which transmits approximately 10 mPa pressure to the cultured cells. Based on research on mechanotransduction and ultrasound effects on cells, gene responses to the audible sound stimulation were analyzed by varying several sound parameters: frequency, wave form, composition, and exposure time. Real-time quantitative PCR analyses revealed a distinct suppressive effect for several mechanosensitive and ultrasound-sensitive genes that were triggered by sounds. The effect was clearly observed in a wave form- and pressure level-specific manner, rather than the frequency, and persisted for several hours. At least two mechanisms are likely to be involved in this sound response: transcriptional control and RNA degradation. ST2 stromal cells and C2C12 myoblasts exhibited a robust response, whereas NIH3T3 cells were partially and NB2a neuroblastoma cells were completely insensitive, suggesting a cell type-specific response to sound. These findings reveal a cell-level systematic response to audible sound and uncover novel relationships between life and sound.
[Mh] Termos MeSH primário: Estimulação Acústica
Regulação da Expressão Gênica
Mecanotransdução Celular/genética
Som
[Mh] Termos MeSH secundário: Animais
Linhagem Celular
Camundongos
Reação em Cadeia da Polimerase em Tempo Real
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0188764


  5 / 39459 MEDLINE  
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[PMID]:29293637
[Au] Autor:Paladini RE; Diana L; Zito GA; Nyffeler T; Wyss P; Mosimann UP; Müri RM; Nef T; Cazzoli D
[Ad] Endereço:Gerontechnology and Rehabilitation Group, University of Bern, Bern, Switzerland.
[Ti] Título:Attentional reorienting triggers spatial asymmetries in a search task with cross-modal spatial cueing.
[So] Source:PLoS One;13(1):e0190677, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Cross-modal spatial cueing can affect performance in a visual search task. For example, search performance improves if a visual target and an auditory cue originate from the same spatial location, and it deteriorates if they originate from different locations. Moreover, it has recently been postulated that multisensory settings, i.e., experimental settings, in which critical stimuli are concurrently presented in different sensory modalities (e.g., visual and auditory), may trigger asymmetries in visuospatial attention. Thereby, a facilitation has been observed for visual stimuli presented in the right compared to the left visual space. However, it remains unclear whether auditory cueing of attention differentially affects search performance in the left and the right hemifields in audio-visual search tasks. The present study investigated whether spatial asymmetries would occur in a search task with cross-modal spatial cueing. Participants completed a visual search task that contained no auditory cues (i.e., unimodal visual condition), spatially congruent, spatially incongruent, and spatially non-informative auditory cues. To further assess participants' accuracy in localising the auditory cues, a unimodal auditory spatial localisation task was also administered. The results demonstrated no left/right asymmetries in the unimodal visual search condition. Both an additional incongruent, as well as a spatially non-informative, auditory cue resulted in lateral asymmetries. Thereby, search times were increased for targets presented in the left compared to the right hemifield. No such spatial asymmetry was observed in the congruent condition. However, participants' performance in the congruent condition was modulated by their tone localisation accuracy. The findings of the present study demonstrate that spatial asymmetries in multisensory processing depend on the validity of the cross-modal cues, and occur under specific attentional conditions, i.e., when visual attention has to be reoriented towards the left hemifield.
[Mh] Termos MeSH primário: Atenção
Sinais (Psicologia)
Análise e Desempenho de Tarefas
[Mh] Termos MeSH secundário: Estimulação Acústica/métodos
Adolescente
Adulto
Feminino
Seres Humanos
Masculino
Meia-Idade
Estimulação Luminosa/métodos
Tempo de Reação
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180221
[Lr] Data última revisão:
180221
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180103
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190677


  6 / 39459 MEDLINE  
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[PMID]:29300763
[Au] Autor:Parmentier FBR; Pacheco-Unguetti AP; Valero S
[Ad] Endereço:Neuropsychology & Cognition Group, Department of Psychology and Research Institute for Health Sciences (iUNICS), University of the Balearic Islands, Palma, Balearic Islands, Spain.
[Ti] Título:Food words distract the hungry: Evidence of involuntary semantic processing of task-irrelevant but biologically-relevant unexpected auditory words.
[So] Source:PLoS One;13(1):e0190644, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Rare changes in a stream of otherwise repeated task-irrelevant sounds break through selective attention and disrupt performance in an unrelated visual task by triggering shifts of attention to and from the deviant sound (deviance distraction). Evidence indicates that the involuntary orientation of attention to unexpected sounds is followed by their semantic processing. However, past demonstrations relied on tasks in which the meaning of the deviant sounds overlapped with features of the primary task. Here we examine whether such processing is observed when no such overlap is present but sounds carry some relevance to the participants' biological need to eat when hungry. We report the results of an experiment in which hungry and satiated participants partook in a cross-modal oddball task in which they categorized visual digits (odd/even) while ignoring task-irrelevant sounds. On most trials the irrelevant sound was a sinewave tone (standard sound). On the remaining trials, deviant sounds consisted of spoken words related to food (food deviants) or control words (control deviants). Questionnaire data confirmed state (but not trait) differences between the two groups with respect to food craving, as well as a greater desire to eat the food corresponding to the food-related words in the hungry relative to the satiated participants. The results of the oddball task revealed that food deviants produced greater distraction (longer response times) than control deviants in hungry participants while the reverse effect was observed in satiated participants. This effect was observed in the first block of trials but disappeared thereafter, reflecting semantic saturation. Our results suggest that (1) the semantic content of deviant sounds is involuntarily processed even when sharing no feature with the primary task; and that (2) distraction by deviant sounds can be modulated by the participants' biological needs.
[Mh] Termos MeSH primário: Estimulação Acústica
Percepção Auditiva
Fome
[Mh] Termos MeSH secundário: Seres Humanos
Análise e Desempenho de Tarefas
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180215
[Lr] Data última revisão:
180215
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180105
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190644


  7 / 39459 MEDLINE  
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[PMID]:29328642
[Au] Autor:Mihailovic D; Duric N; Kovacevic I; Mihailovic D
[Ti] Título:The effects of industrial noise of higher spectrum on the workers' auditory perception abilities.
[So] Source:Vojnosanit Pregl;73(11):1030-7, 2016 Aug.
[Is] ISSN:0042-8450
[Cp] País de publicação:Serbia
[La] Idioma:eng
[Ab] Resumo:Background/Aim: Results of previous studies gave support to the idea that machines in power plants produce noise of different levels of loudness and frequency, and that it could cause deterioration of the hearing ability of workers. As a matter of fact, noiseinduced hearing loss is the most widespread occupational disease nowadays. As noise is a complex acoustic phenomenon, more factors have to be considered when studying it, such as frequency, intensity and the period of exposure. The aim of this study was to find if there are differences in the absolute threshold of hearing between workers in the factory production lines that are constantly exposed to the industrial noise of higher spectrum and those exposed to the noise of standard spectrum at different frequencies of sound. Methods: In the research plan, there were 308 workers employed in the production line of the Factory "Knjaz Milos", Arandelovac. A total of 205 of them were working in the conditions of higher spectrum noise (4,000 Hz ­ 8,000 Hz) and 103 workers were exposed to standard noise spectrum (31.5 Hz ­ 2,000.0 Hz). The objective measures of noise (frequency and amplitude) were acquired by phonometer, and measures of absolute threshold of hearing for both ears were obtained by audiometer by exposure to nine sound frequency levels. Data were statistically analyzed by establishing the significance of differences between absolute thresholds of hearing for both groups and for all nine frequency levels. Results: It was found that the absolute threshold of hearing is significantly higher for the group exposed to highfrequency noise at the 4,000 Hz and 8,000 Hz levels of frequency. Conclusion: Reduction of hearing sensitivity is evident for those exposed to higher spectrum noise, which is particularly evident at the higher frequency levels. Employees are often unaware of its effects because they are the results of prolonged exposure. Therefore, working in those conditions requires preventive measures and regular testing of the hearing ability.
[Mh] Termos MeSH primário: Percepção Auditiva
Perda Auditiva Provocada por Ruído/etiologia
Perda Auditiva Provocada por Ruído/psicologia
Ruído/efeitos adversos
Doenças Profissionais/etiologia
Exposição Ocupacional/efeitos adversos
Pessoas com Deficiência Auditiva/psicologia
[Mh] Termos MeSH secundário: Estimulação Acústica
Acústica
Audiometria
Limiar Auditivo
Feminino
Perda Auditiva Provocada por Ruído/diagnóstico
Seres Humanos
Estudos Longitudinais
Masculino
Doenças Profissionais/diagnóstico
Doenças Profissionais/psicologia
Fatores de Risco
Espectrografia do Som
Fatores de Tempo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180113
[St] Status:MEDLINE
[do] DOI:10.2298/VSP140416119M


  8 / 39459 MEDLINE  
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[PMID]:28460299
[Au] Autor:Laing CE
[Ad] Endereço:Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA. Electronic address: catherine.laing@duke.edu.
[Ti] Título:A perceptual advantage for onomatopoeia in early word learning: Evidence from eye-tracking.
[So] Source:J Exp Child Psychol;161:32-45, 2017 Sep.
[Is] ISSN:1096-0457
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:A perceptual advantage for iconic forms in infant language learning has been widely reported in the literature, termed the "sound symbolism bootstrapping hypothesis" by Imai and Kita (2014). However, empirical research in this area is limited mainly to sound symbolic forms, which are very common in languages such as Japanese but less so in Indo-European languages such as English. In this study, we extended this body of research to onomatopoeia-words that are thought to be present across most of the world's languages and that are known to be dominant in infants' early lexicons. In a picture-mapping task, 10- and 11-month-old infants showed a processing advantage for onomatopoeia (e.g., woof woof) over their conventional counterparts (e.g., doggie). However, further analysis suggests that the input may play a key role in infants' experience and processing of these forms.
[Mh] Termos MeSH primário: Desenvolvimento da Linguagem
Fonética
Aprendizagem Verbal/fisiologia
[Mh] Termos MeSH secundário: Estimulação Acústica
Movimentos Oculares/fisiologia
Feminino
Seres Humanos
Lactente
Simbolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170502
[St] Status:MEDLINE


  9 / 39459 MEDLINE  
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[PMID]:29364931
[Au] Autor:Espinoza-Varas B; Hilton J; Guo S
[Ad] Endereço:Department of Communication Sciences & Disorders, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States of America.
[Ti] Título:Object-based attention modulates the discrimination of level increments in stop-consonant noise bursts.
[So] Source:PLoS One;13(1):e0190956, 2018.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:This study tested the hypothesis that object-based attention modulates the discrimination of level increments in stop-consonant noise bursts. With consonant-vowel-consonant (CvC) words consisting of an ≈80-dB vowel (v), a pre-vocalic (Cv) and a post-vocalic (vC) stop-consonant noise burst (≈60-dB SPL), we measured discrimination thresholds (LDTs) for level increments (ΔL) in the noise bursts presented either in CvC context or in isolation. In the 2-interval 2-alternative forced-choice task, each observation interval presented a CvC word (e.g., /pæk/ /pæk/), and normal-hearing participants had to discern ΔL in the Cv or vC burst. Based on the linguistic word labels, the auditory events of each trial were perceived as two auditory objects (Cv-v-vC and Cv-v-vC) that group together the bursts and vowels, hindering selective attention to ΔL. To discern ΔL in Cv or vC, the events must be reorganized into three auditory objects: the to-be-attended pre-vocalic (Cv-Cv) or post-vocalic burst pair (vC-vC), and the to-be-ignored vowel pair (v-v). Our results suggest that instead of being automatic this reorganization requires training, in spite of using familiar CvC words. Relative to bursts in isolation, bursts in context always produced inferior ΔL discrimination accuracy (a context effect), which depended strongly on the acoustic separation between the bursts and the vowel, being much keener for the object apart from (post-vocalic) than for the object adjoining (pre-vocalic) the vowel (a temporal-position effect). Variability in CvC dimensions that did not alter the noise-burst perceptual grouping had minor effects on discrimination accuracy. In addition to being robust and persistent, these effects are relatively general, evincing in forced-choice tasks with one or two observation intervals, with or without variability in the temporal position of ΔL, and with either fixed or roving CvC standards. The results lend support to the hypothesis.
[Mh] Termos MeSH primário: Atenção/fisiologia
Percepção da Fala/fisiologia
[Mh] Termos MeSH secundário: Estimulação Acústica
Adulto
Limiar Auditivo
Feminino
Seres Humanos
Masculino
Meia-Idade
Ruído/efeitos adversos
Fonética
Psicoacústica
Acústica da Fala
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180209
[Lr] Data última revisão:
180209
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180125
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0190956


  10 / 39459 MEDLINE  
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[PMID]:28993219
[Au] Autor:Ma J; Leung LS
[Ad] Endereço:Department of Physiology and Pharmacology, The University of Western Ontario, London N6A 5C1, Canada. Electronic address: jma2@uwo.ca.
[Ti] Título:Involvement of posterior cingulate cortex in ketamine-induced psychosis relevant behaviors in rats.
[So] Source:Behav Brain Res;338:17-27, 2018 Feb 15.
[Is] ISSN:1872-7549
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:The involvement of posterior cingulate cortex (PCC) on ketamine-induced psychosis relevant behaviors was investigated in rats. Bilateral infusion of muscimol, a GABA receptor agonist, into the PCC significantly antagonized ketamine-induced deficit in prepulse inhibition of a startle reflex (PPI), deficit in gating of hippocampal auditory evoked potentials, and behavioral hyperlocomotion in a dose dependent manner. Local infusion of ketamine directly into the PCC also induced a PPI deficit. Systemic injection of ketamine (3mg/kg,s.c.) induced an increase in power of electrographic activity in the gamma band (30-100Hz) in both the PCC and the hippocampus; peak theta (4-10Hz) power was not significantly altered, but peak theta frequency was increased by ketamine. In order to exclude volume conduction from the hippocampus to PCC, inactivation of the hippocampus was made by local infusion of muscimol into the hippocampus prior to ketamine administration. Muscimol in the hippocampus effectively blocked ketamine-induced increase of gamma power in the hippocampus but not in the PCC, suggesting independent generation of gamma waves in PCC and hippocampus. It is suggested that the PCC is part of the brain network mediating ketamine-induced psychosis related behaviors.
[Mh] Termos MeSH primário: Comportamento Animal/efeitos dos fármacos
Antagonistas de Aminoácidos Excitatórios/farmacologia
Giro do Cíngulo/fisiopatologia
Ketamina/farmacologia
Psicoses Induzidas por Substâncias/fisiopatologia
Reflexo de Sobressalto/efeitos dos fármacos
[Mh] Termos MeSH secundário: Estimulação Acústica
Animais
Relação Dose-Resposta a Droga
Potenciais Evocados Auditivos/efeitos dos fármacos
Giro do Cíngulo/efeitos dos fármacos
Hipocampo/efeitos dos fármacos
Hipocampo/fisiopatologia
Ratos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Excitatory Amino Acid Antagonists); 690G0D6V8H (Ketamine)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180207
[Lr] Data última revisão:
180207
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171011
[St] Status:MEDLINE



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