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[PMID]:29196612
[Au] Autor:Mahesh S; Mallappa M; Tsintzas D; Vithoulkas G
[Ad] Endereço:Centre for Classical Homeopathy, Vijayanagar, Bangalore, Karnataka, India.
[Ti] Título:Homeopathic Treatment of Vitiligo: A Report of Fourteen Cases.
[So] Source:Am J Case Rep;18:1276-1283, 2017 Dec 02.
[Is] ISSN:1941-5923
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND Vitiligo, also known as leukoderma, is an autoimmune skin condition that results in the loss of melanin pigment. Vitiligo is not a rare condition but is difficult to treat and is associated with psychological distress. CASE REPORT A series of 14 cases of vitiligo are presented that were treated with individualized homeopathic remedies that were based on plant, animal, or mineral compounds. There were 13 women and one man in the case series, with a mean age 29.8 years, and a mean follow-up from treatment of 58 months. The mean time between the onset of the appearance of vitiligo and the first consultation at our clinic was 96 months. Homeopathic treatment for patients is holistic and was performed on an individualized basis as described in this case series. Photographic images of the skin are presented before and after treatment. CONCLUSIONS In 14 patients with vitiligo treated with individualized homeopathy, the best results were achieved in the patients who were treated in the early stages of the disease. We believe that homeopathy may be effective in the early stages of vitiligo, but large controlled clinical studies are needed in this area.
[Mh] Termos MeSH primário: Homeopatia
Vitiligo/terapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Criança
Feminino
Seres Humanos
Masculino
Meia-Idade
Tempo para o Tratamento
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180109
[Lr] Data última revisão:
180109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171203
[St] Status:MEDLINE


  2 / 3676 MEDLINE  
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[PMID]:29210253
[Au] Autor:Michaux G
[Ti] Título:Should Anthroposophic Medicinal Products Be Regulated in Europe?
[So] Source:Eur J Health Law;24(1):46-66, 2017 Mar.
[Is] ISSN:0929-0273
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:European Commission's reports suggest that the European Union should address the status of anthroposophic products, i.e. products that are developed, manufactured and prescribed in accordance with the holistic approach on which anthroposophic medicine is based. Anthroposophic products cannot be placed as such on the European market because they cannot meet the marketing authorisation or even registration requirements set out by European or national pharmaceutical law. Yet, the 95-year European tradition and good safety profile of anthroposophic products justify giving them an easier access to market. Such access can result from specific rules on anthroposophic products, but can be more efficiently achieved by encouraging the Member States to better apply the existing rules on marketing authorisation procedures or on registration of homeopathic and traditional herbal medicinal products, or by including anthroposophic substances, manufacturing methods or uses in monographs.
[Mh] Termos MeSH primário: Aprovação de Drogas/legislação & jurisprudência
Homeopatia/legislação & jurisprudência
Legislação de Medicamentos
Fitoterapia
[Mh] Termos MeSH secundário: Europa (Continente)
Regulamentação Governamental
Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171228
[Lr] Data última revisão:
171228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171207
[St] Status:MEDLINE


  3 / 3676 MEDLINE  
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[PMID]:29173783
[Au] Autor:Smolinske SC
[Ad] Endereço:New Mexico Poison and Drug Information Center, Pharmacy Practice and Administration, University of New Mexico, MSC 07 4390, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address: SSmolinske@salud.unm.edu.
[Ti] Título:Dietary Supplements in Children.
[So] Source:Pediatr Clin North Am;64(6):1243-1255, 2017 Dec.
[Is] ISSN:1557-8240
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:High-quality systematic reviews of use of herbal or homeopathic remedies in children often suffer from design flaws, such as not following PRISMA guidelines, inconsistent outcome measurements, and paucity of high-quality studies. Herbal remedies have modest demonstrated benefits with insufficient evidence to recommend any particular supplement. Homeopathic remedies have no role in treatment of pediatric conditions, and have been associated with great harm in infants given homeopathic teething products. Two types of herbal supplements are associated with high risk in adolescents, energy drinks and adulterated weight-loss products. Parents should be counseled about risks of these products.
[Mh] Termos MeSH primário: Suplementos Nutricionais
Homeopatia
[Mh] Termos MeSH secundário: Adolescente
Criança
Seres Humanos
Lactente
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1712
[Cu] Atualização por classe:171204
[Lr] Data última revisão:
171204
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE


  4 / 3676 MEDLINE  
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[PMID]:28915242
[Au] Autor:Ostermann JK; Witt CM; Reinhold T
[Ad] Endereço:Institute for Social Medicine, Epidemiology and Health Economics, Charité - University Medical Center, Berlin, Germany.
[Ti] Título:A retrospective cost-analysis of additional homeopathic treatment in Germany: Long-term economic outcomes.
[So] Source:PLoS One;12(9):e0182897, 2017.
[Is] ISSN:1932-6203
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: This study aimed to provide a long-term cost comparison of patients using additional homeopathic treatment (homeopathy group) with patients using usual care (control group) over an observation period of 33 months. METHODS: Health claims data from a large statutory health insurance company were analysed from both the societal perspective (primary outcome) and from the statutory health insurance perspective (secondary outcome). To compare costs between patient groups, homeopathy and control patients were matched in a 1:1 ratio using propensity scores. Predictor variables for the propensity scores included health care costs and both medical and demographic variables. Health care costs were analysed using an analysis of covariance, adjusted for baseline costs, between groups both across diagnoses and for specific diagnoses over a period of 33 months. Specific diagnoses included depression, migraine, allergic rhinitis, asthma, atopic dermatitis, and headache. RESULTS: Data from 21,939 patients in the homeopathy group (67.4% females) and 21,861 patients in the control group (67.2% females) were analysed. Health care costs over the 33 months were 12,414 EUR [95% CI 12,022-12,805] in the homeopathy group and 10,428 EUR [95% CI 10,036-10,820] in the control group (p<0.0001). The largest cost differences were attributed to productivity losses (homeopathy: EUR 6,289 [6,118-6,460]; control: EUR 5,498 [5,326-5,670], p<0.0001) and outpatient costs (homeopathy: EUR 1,794 [1,770-1,818]; control: EUR 1,438 [1,414-1,462], p<0.0001). Although the costs of the two groups converged over time, cost differences remained over the full 33 months. For all diagnoses, homeopathy patients generated higher costs than control patients. CONCLUSION: The analysis showed that even when following-up over 33 months, there were still cost differences between groups, with higher costs in the homeopathy group.
[Mh] Termos MeSH primário: Custos de Cuidados de Saúde
Homeopatia/economia
[Mh] Termos MeSH secundário: Custos e Análise de Custo
Feminino
Alemanha
Seres Humanos
Masculino
Estudos Retrospectivos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171012
[Lr] Data última revisão:
171012
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170916
[St] Status:MEDLINE
[do] DOI:10.1371/journal.pone.0182897


  5 / 3676 MEDLINE  
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[PMID]:28821700
[Au] Autor:Lees P; Pelligand L; Whiting M; Chambers D; Toutain PL; Whitehead ML
[Ti] Título:Comparison of veterinary drugs and veterinary homeopathy: part 2.
[So] Source:Vet Rec;181(8):198-207, 2017 Aug 19.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:Part 2 of this narrative review outlines the theoretical and practical bases for assessing the efficacy and effectiveness of conventional medicines and homeopathic products. Known and postulated mechanisms of action are critically reviewed. The evidence for clinical efficacy of products in both categories, in the form of practitioner experience, meta-analysis and systematic reviews of clinical trial results, is discussed. The review also addresses problems and pitfalls in assessing data, and the ethical and negative aspects of pharmacology and homeopathy in veterinary medicine.
[Mh] Termos MeSH primário: Doenças dos Animais/terapia
Homeopatia/veterinária
Drogas Veterinárias/uso terapêutico
[Mh] Termos MeSH secundário: Doenças dos Animais/tratamento farmacológico
Animais
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Veterinary Drugs)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170825
[Lr] Data última revisão:
170825
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170820
[St] Status:MEDLINE
[do] DOI:10.1136/vr.104279


  6 / 3676 MEDLINE  
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[PMID]:28801498
[Au] Autor:Lees P; Pelligand L; Whiting M; Chambers D; Toutain PL; Whitehead ML
[Ad] Endereço:Royal Veterinary College, Hawkshead Campus, Hatfield, Hertfordshire AL9 7TA, UK.
[Ti] Título:Comparison of veterinary drugs and veterinary homeopathy: part 1.
[So] Source:Vet Rec;181(7):170-176, 2017 Aug 12.
[Is] ISSN:2042-7670
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of veterinary therapeutics. There remains today a much smaller, but significant, use of homeopathy by veterinary surgeons. Homeopathic products are sometimes administered when conventional drug therapies have not succeeded, but are also used as alternatives to scientifically based therapies and licensed products. The principles underlying the veterinary use of drug-based and homeopathic products are polar opposites; this provides the basis for comparison between them. This two-part review compares and contrasts the two treatment forms in respect of history, constituents, methods of preparation, known or postulated mechanisms underlying responses, the legal basis for use and scientific credibility in the 21st century. Part 1 begins with a consideration of why therapeutic products actually work or appear to do so.
[Mh] Termos MeSH primário: Doenças dos Animais/terapia
Homeopatia/veterinária
Drogas Veterinárias/uso terapêutico
[Mh] Termos MeSH secundário: Doenças dos Animais/tratamento farmacológico
Animais
História do Século XVIII
História do Século XIX
História do Século XX
História do Século XXI
Homeopatia/história
Ensaios Clínicos Controlados Aleatórios como Assunto
Resultado do Tratamento
Drogas Veterinárias/história
[Pt] Tipo de publicação:COMPARATIVE STUDY; HISTORICAL ARTICLE; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Veterinary Drugs)
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170815
[Lr] Data última revisão:
170815
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170813
[St] Status:MEDLINE
[do] DOI:10.1136/vr.104278


  7 / 3676 MEDLINE  
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[PMID]:28731782
[Au] Autor:Gleiss A
[Ad] Endereço:Section of Clinical Biometrics, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna , Vienna, Austria .
[Ti] Título:Identifiability of Components of Complex Interventions Using Factorial Designs.
[So] Source:J Altern Complement Med;23(8):569-574, 2017 Aug.
[Is] ISSN:1557-7708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aim of this contribution is to demonstrate how the component structure of a complex intervention (CI) can be efficiently exploited for study design and statistical analysis by using concepts of factorial designs. Many studies on CIs in complementary and alternative medicine exhibit the structure of factorial designs, where all possible combinations of the levels of two or more treatments occur together. In this contribution, the treatment arms of CI studies are explicitly viewed as factorial combinations of their components. Experimental design offers the general concept of identifiability of effects, that is, unique estimability of the components' effects from the observed data. For factorial designs, a simple cross table representation of the treatment arms can show the components or sums or interactions of components that are identifiable within a given study design. The question of identifiability arises particularly if some combinations of components are not observed (e.g., individualized homeopathic prescription without consultation). Study designs from published homeopathy studies are used for demonstration. CONCLUSIONS: CI studies should explicitly use an intervention's factorial component structure if it is inherent in the treatment arms being compared. In this way, investigators can avoid study designs from which the effects of interest cannot be uniquely estimated and improve the interpretation of estimated effects.
[Mh] Termos MeSH primário: Pesquisa Biomédica
Terapias Complementares
Projetos de Pesquisa
[Mh] Termos MeSH secundário: Homeopatia
Seres Humanos
Modelos Estatísticos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170906
[Lr] Data última revisão:
170906
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170722
[St] Status:MEDLINE
[do] DOI:10.1089/acm.2017.0075


  8 / 3676 MEDLINE  
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[PMID]:28646815
[Au] Autor:Kwiatkowski L; Rice E; Langland J
[Ti] Título:Integrative Treatment of Chronic Abdominal Bloating and Pain Associated With Overgrowth of Small Intestinal Bacteria: A Case Report.
[So] Source:Altern Ther Health Med;23(4):56-61, 2017 Jul.
[Is] ISSN:1078-6791
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Context • Small intestinal bacterial overgrowth (SIBO) is commonly defined as an increased number of bacteria and/or an abnormal type of bacteria in the small intestine. Conventional treatment for SIBO is typically focused on antibiotics to eradicate the bacterial overgrowth. Numerous studies have demonstrated the antimicrobial activity of herbs, and a diet low in fermentable oligo-, di-, and monosaccharides and polyols (FODMAPs) has been shown to enhance antibiotic therapy. Objective • The current case study intended to evaluate the benefits of an alternative, multifaceted approach-including botanical and homeopathic therapies in conjunction with a low-FODMAP diet-in the treatment of SIBO and its associated symptoms. Design • The research team performed a case study. Setting • The study was conducted at SCNM Medical Center (Tempe, AZ, USA). Participant • The participant was a female patient at the SCNM Medical Center with chronic, daily, severe abdominal bloating and pain that particularly worsened after meals and by the end of the day. The patient also had a significant history of chronic constipation that had begun approximately 10 y prior to her experiencing the daily abdominal pain. Intervention • Based on a lactulose breath test for hydrogen and methane, the research team diagnosed the patient with a case of mild SIBO. The treatment approach was multifaceted, involving a low-FODMAP diet, antimicrobial botanical therapy, and homeopathic medicine. Results • The patient's abdominal pain and bloating resolved with the treatment of the SIBO, although her underlying constipation, which was likely associated with other factors, remained. Conclusions • This case study supports an alternative, multifaceted approach to the treatment of SIBO and commonly associated symptoms.
[Mh] Termos MeSH primário: Síndrome da Alça Cega/terapia
Dietoterapia
Homeopatia
Fitoterapia
Probióticos/uso terapêutico
[Mh] Termos MeSH secundário: Dor Abdominal/etiologia
Adulto
Síndrome da Alça Cega/complicações
Síndrome da Alça Cega/diagnóstico
Testes Respiratórios
Doença Crônica
Citrullus colocynthis
Constipação Intestinal/complicações
Dissacarídeos
Feminino
Fermentação
Seres Humanos
Monossacarídeos
Oligossacarídeos
Polímeros
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Disaccharides); 0 (Monosaccharides); 0 (Oligosaccharides); 0 (Polymers); 0 (polyol)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171024
[Lr] Data última revisão:
171024
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170625
[St] Status:MEDLINE


  9 / 3676 MEDLINE  
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[PMID]:28529235
[Au] Autor:Soloski A
[Ti] Título:Alternative Medicine: Contagion and Cure in Karel Capek's The White Plague.
[So] Source:Lit Med;35(1):167-182, 2017.
[Is] ISSN:0278-9671
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Though written amid an atmosphere of unprecedented medical advance in both diagnosis and therapeutics, Karel Capek's The White Plague takes a starkly critical stance against overconfidence in medical science and its dubious ethical orbit. This article explores Capek's censure of those who would privilege scientific interest in disease over the holistic plight of the sufferer. Provocatively, Capek achieves this not only via the play's content, but also-prefiguring aspects of contemporary live art practice by several decades-by placing audience members in worrying proximity to abject ill bodies. Capek proposes a sort of theatrical homeopathy, suggesting that limited exposure to the threat of disease might spur spectators toward empathy for those who suffer and promote a healthier, more compassionate society.
[Mh] Termos MeSH primário: Terapias Complementares/história
Transmissão de Doença Infecciosa/história
Drama/história
Ética Médica/história
Homeopatia/história
Literatura Moderna
Medicina na Literatura
Peste/história
[Mh] Termos MeSH secundário: Tchecoslováquia
História do Século XX
Seres Humanos
[Pt] Tipo de publicação:BIOGRAPHY; HISTORICAL ARTICLE; JOURNAL ARTICLE
[Ps] Nome de pessoa como assunto:��apek K
[Em] Mês de entrada:1708
[Cu] Atualização por classe:170817
[Lr] Data última revisão:
170817
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170523
[St] Status:MEDLINE
[do] DOI:10.1353/lm.2017.0007


  10 / 3676 MEDLINE  
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[PMID]:28437146
[Au] Autor:Banerjee K; Mathie RT; Costelloe C; Howick J
[Ad] Endereço:1 Dr. Kalyan Banerjee's Clinic , New Delhi, India .
[Ti] Título:Homeopathy for Allergic Rhinitis: A Systematic Review.
[So] Source:J Altern Complement Med;23(6):426-444, 2017 Jun.
[Is] ISSN:1557-7708
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The aim of this study was to evaluate the efficacy and effectiveness of homeopathic intervention in the treatment of seasonal or perennial allergic rhinitis (AR). METHOD: Randomized controlled trials evaluating all forms of homeopathic treatment for AR were included in a systematic review (SR) of studies published up to and including December 2015. Two authors independently screened potential studies, extracted data, and assessed risk of bias. Primary outcomes included symptom improvement and total quality-of-life score. Treatment effect size was quantified as mean difference (continuous data), or by risk ratio (RR) and odds ratio (dichotomous data), with 95% confidence intervals (CI). Meta-analysis was performed after assessing heterogeneity and risk of bias. RESULTS: Eleven studies were eligible for SR. All trials were placebo-controlled except one. Six trials used the treatment approach known as isopathy, but they were unsuitable for meta-analysis due to problems of heterogeneity and data extraction. The overall standard of methods and reporting was poor: 8/11 trials were assessed as "high risk of bias"; only one trial, on isopathy for seasonal AR, possessed reliable evidence. Three trials of variable quality (all using Galphimia glauca for seasonal AR) were included in the meta-analysis: nasal symptom relief at 2 and 4 weeks (RR = 1.48 [95% CI 1.24-1.77] and 1.27 [95% CI 1.10-1.46], respectively) favored homeopathy compared with placebo; ocular symptom relief at 2 and 4 weeks also favored homeopathy (RR = 1.55 [95% CI 1.33-1.80] and 1.37 [95% CI 1.21-1.56], respectively). The single trial with reliable evidence had a small positive treatment effect without statistical significance. A homeopathic and a conventional nasal spray produced equivalent improvements in nasal and ocular symptoms. CONCLUSIONS: The low or uncertain overall quality of the evidence warrants caution in drawing firm conclusions about intervention effects. Use of either Galphimia glauca or a homeopathic nasal spray may have small beneficial effects on the nasal and ocular symptoms of AR. The efficacy of isopathic treatment of AR is unclear.
[Mh] Termos MeSH primário: Homeopatia
Rinite Alérgica/terapia
[Mh] Termos MeSH secundário: Seres Humanos
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170626
[Lr] Data última revisão:
170626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170425
[St] Status:MEDLINE
[do] DOI:10.1089/acm.2016.0310



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