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Pesquisa : E02.190.888.249 [Categoria DeCS]
Referências encontradas : 72 [refinar]
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[PMID]:27943458
[Au] Autor:Yadav A; Gupta A
[Ad] Endereço:Defence Institute of Physiology and Allied Sciences (DIPAS), DRDO, Delhi, India.
[Ti] Título:Noninvasive red and near-infrared wavelength-induced photobiomodulation: promoting impaired cutaneous wound healing.
[So] Source:Photodermatol Photoimmunol Photomed;33(1):4-13, 2017 Jan.
[Is] ISSN:1600-0781
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The innumerable intricacies associated with chronic wounds have made the development of new painless, noninvasive, biophysical therapeutic interventions as the focus of current biomedical research. Red and near-infrared light-induced photobiomodulation therapy appears to emerge as a promising drug-free approach for promoting wound healing, reduction in inflammation, pain and restoration of function owing to penetration power in conjunction with their ability to positively modulate the biochemical and molecular responses. This review will describe the physical properties of red and near-infrared light and their interaction with skin and highlight their efficacy of wound repair and regeneration. Near-infrared (800-830 nm) was found to be the most effective and widely studied wavelength range followed by red (630-680 nm) and 904 nm superpulsed light exhibiting beneficial photobiomodulatory effects on impaired dermal wound healing.
[Mh] Termos MeSH primário: Luz
Fototerapia
Fenômenos Fisiológicos da Pele/efeitos da radiação
Pele/efeitos da radiação
Cicatrização/efeitos da radiação
[Mh] Termos MeSH secundário: Animais
Cor
Terapia pela Cor
Seres Humanos
Terapia de Luz Pulsada Intensa
Pele/metabolismo
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Em] Mês de entrada:1703
[Cu] Atualização por classe:170322
[Lr] Data última revisão:
170322
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161213
[St] Status:MEDLINE
[do] DOI:10.1111/phpp.12282


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[PMID]:27573181
[Au] Autor:van Duynhoven JPM; Jacobs DM
[Ad] Endereço:Unilever R&D Vlaardingen, Olivier van Noortlaan 120, 3130AC Vlaardingen, The Netherlands; Laboratory of Biophysics and Wageningen NMR Centre, Wageningen University, Dreijenlaan 3, 6703HA Wageningen, The Netherlands. Electronic address: john-van.duynhoven@unilever.com.
[Ti] Título:Assessment of dietary exposure and effect in humans: The role of NMR.
[So] Source:Prog Nucl Magn Reson Spectrosc;96:58-72, 2016 08.
[Is] ISSN:1873-3301
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:In human nutritional science progress has always depended strongly on analytical measurements for establishing relationships between diet and health. This field has undergone significant changes as a result of the development of NMR and mass spectrometry methods for large scale detection, identification and quantification of metabolites in body fluids. This has allowed systematic studies of the metabolic fingerprints that biological processes leave behind, and has become the research field of metabolomics. As a metabolic profiling technique, NMR is at its best when its unbiased nature, linearity and reproducibility are exploited in well-controlled nutritional intervention and cross-sectional population screening studies. Although its sensitivity is less good than that of mass spectrometry, NMR has maintained a strong position in metabolomics through implementation of standardisation protocols, hyphenation with mass spectrometry and chromatographic techniques, accurate quantification and spectral deconvolution approaches, and high-throughput automation. Thus, NMR-based metabolomics has contributed uniquely to new insights into dietary exposure, in particular by unravelling the metabolic fates of phytochemicals and the discovery of dietary intake markers. NMR profiling has also contributed to the understanding of the subtle effects of diet on central metabolism and lipoprotein metabolism. In order to hold its ground in nutritional metabolomics, NMR will need to step up its performance in sensitivity and resolution; the most promising routes forward are the analytical use of dynamic nuclear polarisation and developments in microcoil construction and automated fractionation.
[Mh] Termos MeSH primário: Líquidos Corporais/química
Dieta
Metabolômica
Ressonância Magnética Nuclear Biomolecular/métodos
Avaliação Nutricional
[Mh] Termos MeSH secundário: Biomarcadores/análise
Biomarcadores/sangue
Biomarcadores/urina
Terapia pela Cor/métodos
Comportamento Alimentar
Seres Humanos
Lipoproteínas/análise
Lipoproteínas/sangue
Lipoproteínas/metabolismo
Lipoproteínas/urina
Espectrometria de Massas/métodos
Polifenóis/análise
Polifenóis/sangue
Polifenóis/metabolismo
Polifenóis/urina
[Pt] Tipo de publicação:JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Biomarkers); 0 (Lipoproteins); 0 (Polyphenols)
[Em] Mês de entrada:1706
[Cu] Atualização por classe:170728
[Lr] Data última revisão:
170728
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160831
[St] Status:MEDLINE


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[PMID]:27396151
[Au] Autor:Shpagina LA; Abramovich SG; Drobyshev VA; Panacheva LA; Titskaya EV; Reshetova GG
[Ti] Título:[Complex use of naphthalane and nonselective chromotherapy in gonarthrosis treatment in rolling stock workers].
[So] Source:Med Tr Prom Ekol;(4):36-40, 2016.
[Is] ISSN:1026-9428
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:Complex treatment using naphthalane applications with nonselective chromotherapy covered 64 engine operators of locomotive crews, aged 40-69 years, having 1-3 stage knee osteoarthrosis. Findings are that optimized treatment schedules effectively reduce intensity of pain, improve functional state of the joints involved, increase life quality of the patients, have no side effects. Comparative analysis of the treatment results showed that efficiency of combined naphthalane and nonselective chromotherapy exceeds isolated naphthalane effects.
[Mh] Termos MeSH primário: Terapia pela Cor/métodos
Naftalenos/farmacologia
Doenças Profissionais/terapia
Osteoartrite/terapia
Ferrovias
[Mh] Termos MeSH secundário: Adulto
Idoso
Seres Humanos
Masculino
Meia-Idade
Naftalenos/administração & dosagem
Doenças Profissionais/tratamento farmacológico
Osteoartrite/tratamento farmacológico
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Naphthalenes); 88451Q4XYF (decalin)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:160711
[Lr] Data última revisão:
160711
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160712
[St] Status:MEDLINE


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[PMID]:27164744
[Au] Autor:Drakon AK; Elfimov MA; Illarionov VE; Ivanova II; Portnov VV
[Ti] Título:[Contemporary potential of nonmedical treatment in ophthalmology].
[So] Source:Med Tr Prom Ekol;(2):6-11, 2016.
[Is] ISSN:1026-9428
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:The article covers treatment results of 90 patients with primary glaucoma simplex of stage 1 and 2 (137 eyes). The authors proved that using a specified magnetotherapy method, when compared to regular medical therapy, causes more fast and marked regression in clinical symptoms and improvement of vision in patients with primary glaucoma simplex of stages 1 and 2.
[Mh] Termos MeSH primário: Terapia pela Cor/métodos
Glaucoma de Ângulo Aberto/terapia
Oftalmologia/métodos
Estimulação Magnética Transcraniana/métodos
[Mh] Termos MeSH secundário: Idoso
Terapia Combinada
Feminino
Seres Humanos
Masculino
Meia-Idade
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mês de entrada:1606
[Cu] Atualização por classe:160511
[Lr] Data última revisão:
160511
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160512
[St] Status:MEDLINE


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[PMID]:27114521
[Au] Autor:Yuan D; Collage RD; Huang H; Zhang X; Kautza BC; Lewis AJ; Zuckerbraun BS; Tsung A; Angus DC; Rosengart MR
[Ad] Endereço:Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213; The Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, China;
[Ti] Título:Blue light reduces organ injury from ischemia and reperfusion.
[So] Source:Proc Natl Acad Sci U S A;113(19):5239-44, 2016 May 10.
[Is] ISSN:1091-6490
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Evidence suggests that light and circadian rhythms profoundly influence the physiologic capacity with which an organism responds to stress. However, the ramifications of light spectrum on the course of critical illness remain to be determined. Here, we show that acute exposure to bright blue spectrum light reduces organ injury by comparison with bright red spectrum or ambient white fluorescent light in two murine models of sterile insult: warm liver ischemia/reperfusion (I/R) and unilateral renal I/R. Exposure to bright blue light before I/R reduced hepatocellular injury and necrosis and reduced acute kidney injury and necrosis. In both models, blue light reduced neutrophil influx, as evidenced by reduced myeloperoxidase (MPO) within each organ, and reduced the release of high-mobility group box 1 (HMGB1), a neutrophil chemotactant and key mediator in the pathogenesis of I/R injury. The protective mechanism appeared to involve an optic pathway and was mediated, in part, by a sympathetic (ß3 adrenergic) pathway that functioned independent of significant alterations in melatonin or corticosterone concentrations to regulate neutrophil recruitment. These data suggest that modifying the spectrum of light may offer therapeutic utility in sterile forms of cellular injury.
[Mh] Termos MeSH primário: Terapia pela Cor/métodos
Cor
Corticosterona/sangue
Traumatismo por Reperfusão/prevenção & controle
Traumatismo por Reperfusão/fisiopatologia
[Mh] Termos MeSH secundário: Animais
Relação Dose-Resposta à Radiação
Proteína HMGB1/sangue
Testes de Função Renal
Testes de Função Hepática
Masculino
Melatonina/sangue
Camundongos
Camundongos Endogâmicos C57BL
Peroxidase/sangue
Dose de Radiação
Traumatismo por Reperfusão/diagnóstico
Índice de Gravidade de Doença
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, N.I.H., EXTRAMURAL
[Nm] Nome de substância:
0 (HMGB1 Protein); 0 (HMGB1 protein, mouse); EC 1.11.1.7 (Peroxidase); JL5DK93RCL (Melatonin); W980KJ009P (Corticosterone)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:170509
[Lr] Data última revisão:
170509
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160427
[St] Status:MEDLINE
[do] DOI:10.1073/pnas.1515296113


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[PMID]:26484622
[Au] Autor:Ebbesen F; Vandborg PK; Madsen PH; Trydal T; Jakobsen LH; Vreman HJ
[Ad] Endereço:Department of Paediatrics, Aalborg University Hospital, Aalborg, Denmark.
[Ti] Título:Effect of phototherapy with turquoise vs. blue LED light of equal irradiance in jaundiced neonates.
[So] Source:Pediatr Res;79(2):308-12, 2016 Feb.
[Is] ISSN:1530-0447
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Blue light with peak emission around 460 nm is the preferred treatment of neonatal hyperbilirubinemia. However, studies using fluorescent light tubes have suggested that turquoise light with peak emission at 490 nm may be more efficient. At present, the predominant light source for phototherapy is light emitting diodes (LEDs). Hence, the aim of this study was to compare the bilirubin-reducing effect in jaundiced neonates treated either with turquoise or with blue LED light with peak emission at 497 or 459 nm, respectively, with equal irradiance on the infants. METHODS: Infants with gestational age ≥33 wk and uncomplicated hyperbilirubinemia were randomized to either turquoise or blue LED light and were treated for 24 h. The mean irradiance footprint at skin level was 5.2 × 10(15) and 5.1 × 10(15) photons/cm(2)/s, respectively. RESULTS: Forty-six infants received turquoise light and 45 received blue light. The median (95% confidence interval) decrease of total serum bilirubin was 35.3% (32.5; 37.3) and 33.1% (27.1; 36.8) for infants treated with turquoise and blue lights, respectively. The difference was nonsignificant (P = 0.53). The decrease was positively correlated to postnatal age and negatively to birth weight. CONCLUSION: Using LED light of equal irradiance, turquoise and blue lights had equal bilirubin-reducing effect on hyperbilirubinemia of neonates.
[Mh] Termos MeSH primário: Bilirrubina/sangue
Terapia pela Cor/instrumentação
Icterícia Neonatal/terapia
[Mh] Termos MeSH secundário: Fatores Etários
Biomarcadores/sangue
Peso ao Nascer
Terapia pela Cor/efeitos adversos
Dinamarca
Regulação para Baixo
Desenho de Equipamento
Feminino
Seres Humanos
Recém-Nascido
Icterícia Neonatal/sangue
Icterícia Neonatal/diagnóstico
Masculino
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0 (Biomarkers); RFM9X3LJ49 (Bilirubin)
[Em] Mês de entrada:1612
[Cu] Atualização por classe:171110
[Lr] Data última revisão:
171110
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151021
[St] Status:MEDLINE
[do] DOI:10.1038/pr.2015.209


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Registro de Ensaios Clínicos
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[PMID]:26044167
[Au] Autor:Pfaff S; Liebmann J; Born M; Merk HF; von Felbert V
[Ad] Endereço:Department of Dermatology and Allergology, University Hospital, RWTH Aachen University, Aachen, Germany.
[Ti] Título:Prospective Randomized Long-Term Study on the Efficacy and Safety of UV-Free Blue Light for Treating Mild Psoriasis Vulgaris.
[So] Source:Dermatology;231(1):24-34, 2015.
[Is] ISSN:1421-9832
[Cp] País de publicação:Switzerland
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Blue light irradiation reduces the proliferation of keratinocytes and modulates T-cell immune response in vitro and has been shown to reduce the severity of psoriasis vulgaris (Pv) in two clinical trials. OBJECTIVE: Evaluation of safety and efficacy of long-term UV-free blue light treatment at home for mild Pv. METHODS: Forty-seven patients with mild Pv were randomized for receiving high-intensity blue light treatment (HI: 453 nm LED, 200 mW/cm(2), n = 24) and low-intensity treatment (LI: 453 nm LED, 100 mW/cm(2), n = 23) of one Pv plaque for 12 weeks. A contralateral control plaque remained untreated. RESULTS: Patient compliance and satisfaction were high. The primary endpoint, change from baseline (CfB) of the Local Psoriasis Severity Index, revealed a significant improvement of the target compared to the control plaques (ΔCfB for the HI group: -0.92 ± 1.10, p = 0.0005; for the LI group: -0.74 ± 1.18, p = 0.0064). CONCLUSION: UV-free blue light home treatment is safe and improves Pv plaques.
[Mh] Termos MeSH primário: Terapia pela Cor/métodos
Psoríase/terapia
[Mh] Termos MeSH secundário: Adulto
Idoso
Terapia pela Cor/efeitos adversos
Método Duplo-Cego
Feminino
Seres Humanos
Hiperpigmentação/etiologia
Masculino
Meia-Idade
Cooperação do Paciente
Satisfação do Paciente
Estudos Prospectivos
Índice de Gravidade de Doença
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Em] Mês de entrada:1603
[Cu] Atualização por classe:150626
[Lr] Data última revisão:
150626
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150606
[Cl] Clinical Trial:ClinicalTrial
[St] Status:MEDLINE
[do] DOI:10.1159/000430495


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[PMID]:25817261
[Au] Autor:Yao LY; Zhu YX; Liu CQ; Jiao RH; Lu YH; Tan RX
[Ad] Endereço:State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, PR China.
[Ti] Título:Preparative separation and purification of fumigaclavine C from fermented mycelia of Aspergillus fumigatus CY018 by macroporous adsorption resin.
[So] Source:J Chromatogr B Analyt Technol Biomed Life Sci;989:122-8, 2015 May 01.
[Is] ISSN:1873-376X
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:In this work, the separation and purification of fumigaclavine C (FC), an ergot alkaloid with strong anti-inflammatory activity from fermented mycelia of Aspergillus fumigatus was systematically evaluated. Among the eight tested resins, the non-polar resin D101 displayed the best adsorption and desorption based on of static adsorption and desorption tests. Adsorption isotherms were constructed on D101 resin and fitted well to the Freundlich model. Dynamic adsorption and desorption tests on a column packed with D101 resin have been investigated for optimization of chromatographic parameters. Under optimized conditions, the contents of FC increased from 7.32% (w/w) in the crude extract to 67.54% in the final product with a recovery yield of 90.35% (w/w) via one run. Furthermore, a lab scale-up separation was carried out, in which the FC content and recovery yield were 65.83% and 90.13%, respectively. These results demonstrated that this adsorption-desorption strategy by using D101 resin was simple and efficient, thus showing potential for large scale purification and preparation of FC in the future.
[Mh] Termos MeSH primário: Aspergillus fumigatus/metabolismo
Terapia pela Cor/métodos
Alcaloides de Claviceps/isolamento & purificação
Alcaloides de Indol/isolamento & purificação
Micélio/química
Resinas Sintéticas/química
[Mh] Termos MeSH secundário: Adsorção
Aspergillus fumigatus/química
Terapia pela Cor/instrumentação
Alcaloides de Claviceps/metabolismo
Fermentação
Alcaloides de Indol/metabolismo
Micélio/metabolismo
Porosidade
[Pt] Tipo de publicação:EVALUATION STUDIES; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Ergot Alkaloids); 0 (Indole Alkaloids); 0 (Resins, Synthetic); 0 (fumigaclavine C)
[Em] Mês de entrada:1512
[Cu] Atualização por classe:150404
[Lr] Data última revisão:
150404
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150331
[St] Status:MEDLINE


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[PMID]:25314761
[Au] Autor:Nikitin AV; Marks SI
[Ti] Título:[The application of chromo- and laserotherapy for the treatment of the patients presenting with chronic obstructive pulmonary disease and concomitant arterial hypertension].
[So] Source:Vopr Kurortol Fizioter Lech Fiz Kult;(4):3-6, 2014 Jul-Aug.
[Is] ISSN:0042-8787
[Cp] País de publicação:Russia (Federation)
[La] Idioma:rus
[Ab] Resumo:This article gives evidence of the effectiveness of chromo- and laser therapy (using infrared and green wavelenth radiation) in combination with basal pharmacotherapy in the patients presenting with combined pathology. The analysis of the data obtained indicates that the proposed approach makes it possible to accelerate normalization of the clinical characteristics, reduce arterial pressure, improve the parameters of external respiration, and increase the duration of remission periods.
[Mh] Termos MeSH primário: Terapia pela Cor/métodos
Hipertensão
Terapia com Luz de Baixa Intensidade/métodos
Doença Pulmonar Obstrutiva Crônica
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Hipertensão/complicações
Hipertensão/fisiopatologia
Hipertensão/terapia
Masculino
Meia-Idade
Doença Pulmonar Obstrutiva Crônica/complicações
Doença Pulmonar Obstrutiva Crônica/fisiopatologia
Doença Pulmonar Obstrutiva Crônica/terapia
Indução de Remissão
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE
[Em] Mês de entrada:1411
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:141016
[St] Status:MEDLINE


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[PMID]:25264124
[Au] Autor:Henriksen TE; Skrede S; Fasmer OB; Hamre B; Grønli J; Lund A
[Ad] Endereço:Department of Clinical Medicine, Section for Psychiatry, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway; Division of Mental Health Care, Valen Hospital, Fonna Local Health Authority, Norway and MoodNet Research Group, Bergen, Norway; Division of Psychiatry, Haukeland University Hospital, Bergen, Norway.
[Ti] Título:Blocking blue light during mania - markedly increased regularity of sleep and rapid improvement of symptoms: a case report.
[So] Source:Bipolar Disord;16(8):894-8, 2014 Dec.
[Is] ISSN:1399-5618
[Cp] País de publicação:Denmark
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: Available pharmacological treatment of mania is insufficient. Virtual darkness therapy (blue light-blocking treatment by means of orange-tinted glasses) is a promising new treatment option for mania. The basis for this might be the recently identified blue light-sensitive retinal photoreceptor, which is solely responsible for light stimulus to the circadian master clock. This is the first case report describing the clinical course of a closely monitored, hospitalized patient in a manic episode first receiving clear-lensed, and then blue light-blocking glasses. METHODS: A 58-year-old Caucasian man, with bipolar I disorder and three previous manic episodes, was hospitalized during a manic episode. In addition to pharmacological treatment, he was treated with clear-lensed glasses for seven days, then one day without glasses, followed by six days of blue light-blocking glasses. During the entire observational period, he wore an actigraph with internal light sensors. RESULTS: Manic symptoms were unaltered during the first seven days. The transition to the blue-blocking regime was followed by a rapid and sustained decline in manic symptoms accompanied by a reduction in total sleep, a reduction in motor activity during sleep intervals, and markedly increased regularity of sleep intervals. The patient's total length of hospital stay was 20 days shorter than the average time during his previous manic episodes. CONCLUSIONS: The unusually rapid decline in symptoms, accompanied by uniform sleep parameter changes toward markedly increased regularity, suggest that blue-blockers might be targeting a central mechanism in the pathophysiology of mania that needs to be explored both in clinical research and in basic science.
[Mh] Termos MeSH primário: Transtorno Bipolar/terapia
Terapia pela Cor
Luz
Privação Sensorial
Sono/efeitos da radiação
[Mh] Termos MeSH secundário: Óculos
Seres Humanos
Masculino
Meia-Idade
Células Fotorreceptoras de Vertebrados/fisiologia
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Em] Mês de entrada:1508
[Cu] Atualização por classe:141204
[Lr] Data última revisão:
141204
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140930
[St] Status:MEDLINE
[do] DOI:10.1111/bdi.12265



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