Base de dados : MEDLINE
Pesquisa : E02.218.707 [Categoria DeCS]
Referências encontradas : 31 [refinar]
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  1 / 31 MEDLINE  
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[PMID]:27930752
[Au] Autor:Joseph AW; Ishii L; Joseph SS; Smith JI; Su P; Bater K; Byrne P; Boahene K; Papel I; Kontis T; Douglas R; Nelson CC; Ishii M
[Ad] Endereço:Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
[Ti] Título:Prevalence of Body Dysmorphic Disorder and Surgeon Diagnostic Accuracy in Facial Plastic and Oculoplastic Surgery Clinics.
[So] Source:JAMA Facial Plast Surg;19(4):269-274, 2017 Jul 01.
[Is] ISSN:2168-6092
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Importance: Body dysmorphic disorder (BDD) is a relative contraindication for facial plastic surgery, but formal screening is not common in practice. The prevalence of BDD in patients seeking facial plastic surgery is not well documented. Objective: To establish the prevalence of BDD across facial plastic and oculoplastic surgery practice settings, and estimate the ability of surgeons to screen for BDD. Design, Setting, and Participants: This multicenter prospective study recruited a cohort of 597 patients who presented to academic and private facial plastic and oculoplastic surgery practices from March 2015 to February 2016. Methods: All patients were screened for BDD using the Body Dysmorphic Disorder Questionnaire (BDDQ). After each clinical encounter, surgeons independently evaluated the likelihood that a participating patient had BDD. Validated instruments were used to assess satisfaction with facial appearance including the FACE-Q, Blepharoplasty Outcomes Evaluation (BOE), Facelift Outcomes Evaluation (FOE), Rhinoplasty Outcomes Evaluation (ROE), and Skin Rejuvenation Outcomes Evaluation (SROE). Results: Across participating practices (9 surgeons, 3 sites), a total of 597 patients were screened for BDD: 342 patients from site 1 (mean [SD] age, 44.2 [16.5] years); 158 patients, site 2 (mean [SD] age, 46.0 [16.2] years), site 3, 97 patients (mean [SD] age, 56.3 [15.5] years). Overall, 58 patients [9.7%] screened positive for BDD by the BDDQ instrument, while only 16 of 402 patients [4.0%] were clinically suspected of BDD by surgeons. A higher percentage of patients presenting for cosmetic surgery (37 of 283 patients [13.1%]) compared with those presenting for reconstructive surgery (21 of 314 patients [6.7%]) screened positive on the BDDQ (odds ratio, 2.10; 95% CI, 1.20-3.68; P = .01). Surgeons were only able to correctly identify 2 of 43 patients (4.7%) who screened positive for BDD on the BDDQ, and the positive likelihood ratio was only 1.19 (95% CI, 0.28-5.07). Patients screening positive for BDD by the BDDQ had lower satisfaction with their appearance as measured by the FACE-Q, ROE, BOE, SROE, and FOE. Conclusions and Relevance: Body dysmorphic disorder is a relatively common condition across facial plastic and oculoplastic surgery practice settings. Patients who screen positive on the BDDQ have lower satisfaction with their facial appearance at baseline. Surgeons have a poor ability to screen for patients with BDD when compared with validated screening instruments such as the BDDQ. Routine implementation of validated BDD screening instruments may improve patient care. Level of Evidence: NA.
[Mh] Termos MeSH primário: Atitude do Pessoal de Saúde
Blefaroplastia/psicologia
Blefaroplastia/estatística & dados numéricos
Transtornos Dismórficos Corporais/diagnóstico
Transtornos Dismórficos Corporais/epidemiologia
Regeneração da Pele por Plasma/psicologia
Regeneração da Pele por Plasma/estatística & dados numéricos
Procedimentos Cirúrgicos Reconstrutivos/psicologia
Procedimentos Cirúrgicos Reconstrutivos/estatística & dados numéricos
Ritidoplastia/psicologia
Ritidoplastia/estatística & dados numéricos
[Mh] Termos MeSH secundário: Adulto
Idoso
Transtornos Dismórficos Corporais/psicologia
Estudos Transversais
Feminino
Seres Humanos
Funções Verossimilhança
Masculino
Programas de Rastreamento
Meia-Idade
Razão de Chances
Satisfação Pessoal
Estudos Prospectivos
Psicometria/estatística & dados numéricos
Sensibilidade e Especificidade
Inquéritos e Questionários
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; VALIDATION STUDIES
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170901
[Lr] Data última revisão:
170901
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:161209
[St] Status:MEDLINE
[do] DOI:10.1001/jamafacial.2016.1535


  2 / 31 MEDLINE  
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[PMID]:26863598
[Au] Autor:Solish N; Rivers JK; Humphrey S; Muhn C; Somogyi C; Lei X; Bhogal M; Caulkins C
[Ad] Endereço:*Department of Dermatology, University of Toronto, Toronto, Ontario, Canada; †Department of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada, and Pacific Dermaesthetics, Vancouver, British Columbia, Canada; ‡Dermetics, Burlington, Ontario, Canada, and Department of Dermatology, McMaster University, Hamilton, Ontario, Canada; §Allergan plc, Irvine, California; ‖Allergan plc, Markham, Ontario, Canada.
[Ti] Título:Efficacy and Safety of OnabotulinumtoxinA Treatment of Forehead Lines: A Multicenter, Randomized, Dose-Ranging Controlled Trial.
[So] Source:Dermatol Surg;42(3):410-9, 2016 Mar.
[Is] ISSN:1524-4725
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Various onabotulinumtoxinA doses are effective in treating forehead lines (FHL), with a trend toward lower doses. OBJECTIVE: To evaluate efficacy and safety of onabotulinumtoxinA dose-ranging treatment of FHL when the frontalis area and glabellar complex are treated together. MATERIALS AND METHODS: Adults with moderate-to-severe FHL received onabotulinumtoxinA 40 U (FHL, 20 U; glabellar lines [GL], 20 U), 30 U (FHL, 10 U; GL, 20 U), or placebo. Response was assessed at weeks 1, 2, day 30, and monthly to day 180. Coprimary efficacy end points were investigator- and subject-assessed Facial Wrinkle Scale scores of none or mild (day 30). Patient-reported outcomes, onset/duration of effect, and adverse events (AEs) were evaluated. RESULTS: Responder rates (investigator/subject, respectively) were 40-U group, 91.2%/89.5%; 30-U group, 86.4%/81.4%; placebo, 1.7%/5.1%. OnabotulinumtoxinA resulted in significantly greater responder rates than placebo (p < .001). Adverse events were mild to moderate and similar between groups (most common AEs: nasopharyngitis [4.6%] and headache [4.0%]). CONCLUSION: Treatment of FHL with onabotulinumtoxinA 40 and 30 U (in frontalis and glabellar complex muscles) was tolerable, effective, and sustained. Both doses significantly reduced FHL severity; however, the 40-U dose demonstrated a trend toward greater sustained benefit and longer duration of effect versus the 30-U dose, with similar AE rates.
[Mh] Termos MeSH primário: Inibidores da Liberação da Acetilcolina/administração & dosagem
Toxinas Botulínicas Tipo A/administração & dosagem
Envelhecimento da Pele/efeitos dos fármacos
[Mh] Termos MeSH secundário: Inibidores da Liberação da Acetilcolina/efeitos adversos
Adulto
Toxinas Botulínicas Tipo A/efeitos adversos
Método Duplo-Cego
Feminino
Testa
Cefaleia/induzido quimicamente
Seres Humanos
Masculino
Meia-Idade
Nasofaringite/induzido quimicamente
Satisfação do Paciente
Regeneração da Pele por Plasma/métodos
Autoimagem
Fatores de Tempo
Resultado do Tratamento
[Pt] Tipo de publicação:JOURNAL ARTICLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Acetylcholine Release Inhibitors); E211KPY694 (onabotulinumtoxinA); EC 3.4.24.69 (Botulinum Toxins, Type A)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:171116
[Lr] Data última revisão:
171116
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:160211
[St] Status:MEDLINE
[do] DOI:10.1097/DSS.0000000000000626


  3 / 31 MEDLINE  
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[PMID]:26684562
[Au] Autor:Jo JH; Jo SH; Lee JH; Kim GY; Kim SM
[Ad] Endereço:Department of Medical Biotechnology, Dongguk University-Bio Medi Campus, Gyeonggi-do, Korea.
[Ti] Título:Analysis of epidermal/dermal temperature changes according to the different cryogen spray cooling conditions.
[So] Source:Technol Health Care;24 Suppl 1:S11-6, 2015.
[Is] ISSN:1878-7401
[Cp] País de publicação:Netherlands
[La] Idioma:eng
[Ab] Resumo:This study measured epidermal and dermal temperatures under different cryogen spray cooling (CSC) conditions to determine the optimum cooling conditions for skin rejuvenation. For this purpose, CSC conditions were applied before a laser transmission for varying spurt times of 50, 150, and 200 ms with delay times of 150 and 200 ms. A long-pulsed 1,064 nm Nd:YAG laser irradiated the skin surface of a pig with a condition of fluence of 26 J/cm2 and a spot diameter of 8 mm. The pulse duration was set to 30 ms during all experiments. This study found that all employed CSC conditions significantly decreased internal-external skin temperatures. Moreover, skin temperatures were influenced more by variations in spurt time of CSC compared with the delay times. Based on these experimental results, two spurt times were selected as the optimum CSC conditions for skin rejuvenation: 50 ms with delay time of 150 and 200 ms and 150 ms with a delay time of 150 and 200 ms.
[Mh] Termos MeSH primário: Propelentes de Aerossol/administração & dosagem
Epiderme/fisiologia
Regeneração da Pele por Plasma/métodos
Temperatura Cutânea/fisiologia
[Mh] Termos MeSH secundário: Animais
Crioterapia/métodos
Suínos
[Pt] Tipo de publicação:JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Aerosol Propellants)
[Em] Mês de entrada:1610
[Cu] Atualização por classe:161230
[Lr] Data última revisão:
161230
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:151220
[St] Status:MEDLINE
[do] DOI:10.3233/THC-151047


  4 / 31 MEDLINE  
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[PMID]:26391324
[Au] Autor:Karrer S; Arndt S
[Ad] Endereço:Klinik und Poliklinik für Dermatologie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93042, Regensburg, Deutschland. sigrid.karrer@ukr.de.
[Ti] Título:[Plasma medicine in dermatology: Mechanisms of action and clinical applications].
[Ti] Título:Plasmamedizin in der Dermatologie : Wirkmechanismen und Anwendungsmöglichkeiten..
[So] Source:Hautarzt;66(11):819-28, 2015 Nov.
[Is] ISSN:1432-1173
[Cp] País de publicação:Germany
[La] Idioma:ger
[Ab] Resumo:Plasma medicine has developed into an innovative field of research showing high potential. Since the establishment of cold atmospheric plasma, new, multifaceted medical treatment opportunities have become available. Within a short time a multidisciplinary special interest group of medical scientists, physicists, and biologists was created, aiming to understand plasma medicine and answer clinical as well as scientific questions. In dermatology, new horizons are being opened for wound healing, tissue regeneration, treatment of skin infections, and tumor therapy. A major task will be the introduction of plasma into clinical medicine and, simultaneously, the further investigation of the mechanisms of action of plasma at the cellular level. Only then can the safety of plasma treatment in patients be assured.
[Mh] Termos MeSH primário: Gases em Plasma/uso terapêutico
Regeneração da Pele por Plasma/métodos
Dermatopatias/imunologia
Dermatopatias/terapia
Pele/imunologia
Cicatrização/fisiologia
[Mh] Termos MeSH secundário: Seres Humanos
Modelos Imunológicos
Dermatopatias/diagnóstico
Resultado do Tratamento
[Pt] Tipo de publicação:ENGLISH ABSTRACT; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Plasma Gases)
[Em] Mês de entrada:1608
[Cu] Atualização por classe:170916
[Lr] Data última revisão:
170916
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150923
[St] Status:MEDLINE
[do] DOI:10.1007/s00105-015-3686-x


  5 / 31 MEDLINE  
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[PMID]:25907154
[Au] Autor:Triana L; Cuadros SC; Triana C; Barbato C; Zambrano M
[Ad] Endereço:Corpus and Rostrum Surgery Center, Cali, Colombia, linatriana@drlinatriana.com.
[Ti] Título:Laser Resurfacing for Latin Skins: The Experience with 665 Cases.
[So] Source:Aesthetic Plast Surg;39(4):582-8, 2015 Aug.
[Is] ISSN:1432-5241
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: CO2 resurfacing and CO2 microfractionated laser systems are reliable tools to improve different facial pathologic skin conditions but are associated with a high rate of complications specially in Fitzpatrick III, IV, and V skin phototypes, predominant in the Latin population, which has pushed many surgeons to change technologies and abandon its use. OBJECTIVE: To compare patient results with the CO2 resurfacing laser and microfractionated CO2 laser resurfacing in all skin types and show similar results to those obtained worldwide in patients with phototypes III, IV, and V. METHODS: Standardized review of medical records from a database of private practice patients treated since January 1998 to July 2012 with SlimE30 MiXto SX(®) CO2 laser. Evaluation of outcomes, complications, and satisfaction of three different modalities of treatment (CO2 ablative laser, CO2 microfractionated and a combination of both) was made. RESULTS: A total of 665 treated patients were included. Ablative CO2 was applied to 80.3 %, CO2 microfractionated to 15.1 %, and mixed treatment to 4.5 % of cases. Globally, hyperpigmentation rates were 30.4 % in the CO2 resurfacing group, 16.3 % when a combination of modalities was applied and 11 % in microfractionated CO2 cases. A steady increase of these rates is shown as the phototype becomes higher. Satisfaction rates were high for all groups: 86.7 % in the mixed group, 82.2 % in the microfractionated CO2, and 79.6 % in the CO2 ablative. CONCLUSIONS: Good results and an acceptable rate of complications in latin skins are obtainable after treating patients with CO2 ablative and microfractionated CO2 systems alone or in combination. Staged treatments and adequate post-procedure care reduce these complications.
[Mh] Termos MeSH primário: Lasers de Gás
Regeneração da Pele por Plasma
[Mh] Termos MeSH secundário: Adulto
Idoso
Idoso de 80 Anos ou mais
Grupos Étnicos
Feminino
Seres Humanos
América Latina
Masculino
Meia-Idade
Estudos Retrospectivos
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Em] Mês de entrada:1604
[Cu] Atualização por classe:150716
[Lr] Data última revisão:
150716
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150425
[St] Status:MEDLINE
[do] DOI:10.1007/s00266-015-0489-5


  6 / 31 MEDLINE  
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[PMID]:25803677
[Au] Autor:Ji Y; Guo L; Zhang Y; Liu Y
[Ad] Endereço:a Department of Dermatology , Third Hospital of Hebei Medical University , Shijiazhuang, Hebei , P. R. China.
[Ti] Título:Comparison of topical anesthesia and subcutaneous infiltration anesthesia with regard to effect of plasma skin regeneration system.
[So] Source:J Cosmet Laser Ther;17(6):330-4, 2015.
[Is] ISSN:1476-4180
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:The plasma skin regeneration (PSR) system is a safe device for skin regeneration, which is usually carried out under local anesthetic to control the pain. Topical anesthesia and subcutaneous infiltration anesthesia are the common and safe anesthetizations. This study was undertaken to evaluate the effects of PSR after using topical anesthetization as compared with subcutaneous infiltration anesthesia, thereby inquiring into the effect of subcutaneous infiltration anesthesia in PSR and increasing electivity for clinical work. 14 Sprague Dawley rats were randomly utilized in this experiment. After adequate sedation and depilation, the rat's back was randomly divided into three experimental regions marked as A, B, and C. A and B were treated with lidocaine cream and lidocaine hydrochloride, respectively, before PSR. C was treated solely with PSR without any anesthesia. Biopsies were taken from all treatment sites at 4 and 30 days after treatment to observe the skin necrosis and thickness of new collagen fiber. Histopathologic examination was performed by observers blinded to the treatment conditions. In this analysis, there was a statistically significant reduction (P < 0.01) in the skin necrosis and thickness of new collagen fiber in the topical anesthesia group compared with that in the other two groups, while a statistically significant increase (P < 0.01) in the subcutaneous infiltration anesthesia group. The results suggest that subcutaneous infiltration anesthesia group showed a deeper range of tissue effects via the treatment of PSR as compared with the topical anesthesia and the control groups. Meanwhile, the effect of the topical anesthesia was the lowest. So we conclude that subcutaneous infiltration anesthesia for PSR treatment was superior to that of the topical anesthesia.
[Mh] Termos MeSH primário: Anestésicos Locais/administração & dosagem
Lidocaína/administração & dosagem
Regeneração da Pele por Plasma
[Mh] Termos MeSH secundário: Administração Tópica
Animais
Colágeno/fisiologia
Injeções Subcutâneas
Modelos Animais
Necrose
Distribuição Aleatória
Ratos Sprague-Dawley
Pele/patologia
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Anesthetics, Local); 9007-34-5 (Collagen); 98PI200987 (Lidocaine)
[Em] Mês de entrada:1607
[Cu] Atualização por classe:151021
[Lr] Data última revisão:
151021
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:150325
[St] Status:MEDLINE
[do] DOI:10.3109/14764172.2015.1027233


  7 / 31 MEDLINE  
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[PMID]:24992275
[Au] Autor:Cannarozzo G; Sannino M; Tamburi F; Chiricozzi A; Saraceno R; Morini C; Nisticò S
[Ad] Endereço:1 Lasers in Dermatology, University of Rome , Tor Vergata, Italy .
[Ti] Título:Deep pulse fractional CO2 laser combined with a radiofrequency system: results of a case series.
[So] Source:Photomed Laser Surg;32(7):409-12, 2014 Jul.
[Is] ISSN:1557-8550
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: The purpose of this study was evaluation of the safety and efficacy of this new combined technology that adds deep ablation to thermal stimulation. BACKGROUND DATA: Minimally ablative or subablative lasers, such as fractional CO2 lasers, have been developed in an attempt to achieve the same clinical results observed with traditional ablative lasers, but with fewer side effects. Despite being an ablative laser, the system used in this study is able to produce a fractional supply of the beam of light. Fractional ablation of skin is performed through the development of microscopic vertical columns surrounded by spared areas of epidermis and dermis, ensuring rapid wound healing and minimum down time. Simultaneous synchronized delivery of a radiofrequency (RF) current to the deeper layers of the skin completes the therapeutic scenario, ensuring an effective skin tightening effect over the entire treated area. METHODS: Nine adult patients were treated for wrinkles and acne scars using this new laser technology. An independent observer evaluated the improvement using a five point scale. RESULTS: All patients had good results in terms of improvement of skin texture, with mild and transitory side effects. CONCLUSIONS: This novel combined system produced improvement in wrinkles and acne scars, with progressive enhancement of skin tone and elasticity.
[Mh] Termos MeSH primário: Procedimentos Cirúrgicos Dermatológicos/métodos
Lasers de Gás/uso terapêutico
[Mh] Termos MeSH secundário: Adulto
Idoso
Feminino
Seres Humanos
Masculino
Meia-Idade
Regeneração da Pele por Plasma
Rejuvenescimento
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1602
[Cu] Atualização por classe:140704
[Lr] Data última revisão:
140704
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140704
[St] Status:MEDLINE
[do] DOI:10.1089/pho.2014.3733


  8 / 31 MEDLINE  
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[PMID]:24745383
[Au] Autor:Duplechain JK
[Ad] Endereço:1103 Kaliste Saloom Road, Suite 300, Lafayette, LA 70508, USA. Electronic address: jkdmd@drduplechain.com.
[Ti] Título:Neck skin rejuvenation.
[So] Source:Facial Plast Surg Clin North Am;22(2):203-16, 2014 May.
[Is] ISSN:1558-1926
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The author of this article uses the pulsed ablative CO2 laser for resurfacing of the neck and face, based on the gold standard status of the CO2 laser and a novel post-treatment plan that greatly reduces adverse effects traditionally associated with fully ablative resurfacing. The croton oil peel is an inexpensive and effective modality for rejuvenating neck skin. The use of either technique as an adjunct to neck lift surgery, with or without facelift surgery, permits surgeons to fulfill the expectations of patients who want the skin of their face and neck to be homogeneous and more attractive.
[Mh] Termos MeSH primário: Técnicas Cosméticas
Rejuvenescimento
Envelhecimento da Pele
[Mh] Termos MeSH secundário: Toxinas Botulínicas/uso terapêutico
Técnicas Cosméticas/efeitos adversos
Dermabrasão
Fármacos Dermatológicos/uso terapêutico
Feminino
Seres Humanos
Lasers de Gás/efeitos adversos
Lasers de Gás/uso terapêutico
Meia-Idade
Regeneração da Pele por Plasma
Ritidoplastia/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; REVIEW
[Nm] Nome de substância:
0 (Dermatologic Agents); EC 3.4.24.69 (Botulinum Toxins)
[Em] Mês de entrada:1412
[Cu] Atualização por classe:140421
[Lr] Data última revisão:
140421
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:140422
[St] Status:MEDLINE


  9 / 31 MEDLINE  
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[PMID]:24488638
[Au] Autor:Agrawal N; Smith G; Heffelfinger R
[Ad] Endereço:Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.
[Ti] Título:Ablative skin resurfacing.
[So] Source:Facial Plast Surg;30(1):55-61, 2014 Feb.
[Is] ISSN:1098-8793
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Ablative laser resurfacing has evolved as a safe and effective treatment for skin rejuvenation. Although traditional lasers were associated with significant thermal damage and lengthy recovery, advances in laser technology have improved safety profiles and reduced social downtime. CO2 lasers remain the gold standard of treatment, and fractional ablative devices capable of achieving remarkable clinical improvement with fewer side effects and shorter recovery times have made it a more practical option for patients. Although ablative resurfacing has become safer, careful patient selection and choice of suitable laser parameters are essential to minimize complications and optimize outcomes. This article describes the current modalities used in ablative laser skin resurfacing and examines their efficacy, indications, and possible side effects.
[Mh] Termos MeSH primário: Técnicas de Ablação
Técnicas Cosméticas
Procedimentos Cirúrgicos Dermatológicos
[Mh] Termos MeSH secundário: Seres Humanos
Regeneração da Pele por Plasma
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1509
[Cu] Atualização por classe:140203
[Lr] Data última revisão:
140203
[Sb] Subgrupo de revista:D
[Da] Data de entrada para processamento:140204
[St] Status:MEDLINE
[do] DOI:10.1055/s-0033-1364223


  10 / 31 MEDLINE  
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[PMID]:24375476
[Au] Autor:Sanderson AR; Wu EC; Liaw LH; Garg R; Gangnes RA
[Ad] Endereço:Department of Otolaryngology, University of California, Irvine, 101 The City Drive, Orange, California, 92868.
[Ti] Título:The effect of topical anesthetic hydration on the depth of thermal injury from the plasma skin regeneration device.
[So] Source:Lasers Surg Med;46(2):127-31, 2014 Feb.
[Is] ISSN:1096-9101
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND AND OBJECTIVES: The plasma skin regeneration (PSR) device delivers thermal energy to the skin by converting nitrogen gas to plasma. Prior to treatment, hydration of the skin is recommended as it is thought to limit the zone of thermal damage. However, there is limited data on optimal hydration time. This pilot study aims to determine the effect of topical anesthetic application time on the depth of thermal injury from a PSR device using histology. STUDY DESIGN/MATERIALS AND METHODS: PSR (1.8 and 3.5 J) was performed after 0, 30, or 60 minutes of topical anesthetic application. Rhytidectomy was then performed and skin was fixed for histologic analysis. Four patients (two control and four treatment sites per patient) undergoing rhytidectomy were recruited for the study. Each patient served as his/her own control (no hydration). A scoring system for tissue injury was developed. Epidermal injury, the presence of vacuolization, blistering, damage to adnexal structures, and depth of dermal collagen changes were evaluated in over 1,400 high-power microscopy fields. RESULTS: There was a significant difference in the average thermal injury score, depth of thermal damage, and epidermal injury when comparing controls to 30 minutes of hydration (P = 0.012, 0.012, 0.017, respectively). There was no statistical difference between controls and 60 minutes of hydration or between 30 and 60 minutes of hydration. Epidermal vacuolization at low energy and patchy distribution of thermal injury was also observed. CONCLUSION: Topical hydration influences the amount of thermal damage when applied to skin for 30 minutes prior to treatment with the PSR device. There was a trend toward decreasing thermal damage at 60 minutes, and there was no difference between treatment for 30 or 60 minutes. The data suggest that application of topical anesthetic for a short period of time prior to treatment with the PSR device is cost-effective, safe, and may be clinically beneficial.
[Mh] Termos MeSH primário: Anestésicos Locais/uso terapêutico
Queimaduras/prevenção & controle
Temperatura Alta/efeitos adversos
Regeneração da Pele por Plasma/efeitos adversos
Pele/lesões
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Idoso de 80 Anos ou mais
Benzocaína/uso terapêutico
Queimaduras/etiologia
Combinação de Medicamentos
Feminino
Seres Humanos
Lidocaína/uso terapêutico
Masculino
Meia-Idade
Projetos Piloto
Regeneração da Pele por Plasma/instrumentação
Ritidoplastia
Método Simples-Cego
Pele/patologia
Tetracaína/uso terapêutico
Fatores de Tempo
Adulto Jovem
[Pt] Tipo de publicação:CONTROLLED CLINICAL TRIAL; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Anesthetics, Local); 0 (Drug Combinations); 0619F35CGV (Tetracaine); 98PI200987 (Lidocaine); U3RSY48JW5 (Benzocaine)
[Em] Mês de entrada:1410
[Cu] Atualização por classe:151119
[Lr] Data última revisão:
151119
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:131231
[St] Status:MEDLINE
[do] DOI:10.1002/lsm.22210



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