Base de dados : MEDLINE
Pesquisa : E02.319.805 [Categoria DeCS]
Referências encontradas : 4879 [refinar]
Mostrando: 1 .. 10   no formato [Detalhado]

página 1 de 488 ir para página                         

  1 / 4879 MEDLINE  
              next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29489686
[Au] Autor:Shi X; Yu S; Wang F; Zhao Q; Xu H; Li B
[Ad] Endereço:Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong University.
[Ti] Título:A gastrointestinal stromal tumor with acute bleeding: Management and nursing.
[So] Source:Medicine (Baltimore);97(9):e9874, 2018 Mar.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors involving the gastrointestinal tract. A small percentage of GISTs may cause acute gastrointestinal bleeding, which requires urgent surgical intervention. PATIENT CONCERNS: In this case report, we present a 62-year-old male patient with who was hospitalized due to acute bleeding. DIAGNOSES: The patient was diagnosed as GIST with low risk. INTERVENTIONS: The patient was treated endoscopically with polidocanol sclerotherapy. OUTCOMES: The mass was removed completely, and the patient was discharged at day 9 after operation. LESSONS: This case indicates that GIST can present as massive upper gastrointestinal bleeding and urgent endoscopic sclerotherapy can be life-saving. The endoscopical intervention may be a good alternative for emergency.
[Mh] Termos MeSH primário: Hemorragia Gastrointestinal/etiologia
Neoplasias Gastrointestinais/complicações
Tumores do Estroma Gastrointestinal/complicações
[Mh] Termos MeSH secundário: Hemorragia Gastrointestinal/terapia
Neoplasias Gastrointestinais/terapia
Tumores do Estroma Gastrointestinal/terapia
Seres Humanos
Masculino
Meia-Idade
Polietilenoglicóis/uso terapêutico
Soluções Esclerosantes/uso terapêutico
Escleroterapia/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sclerosing Solutions); 0AWH8BFG9A (polidocanol); 30IQX730WE (Polyethylene Glycols)
[Em] Mês de entrada:1803
[Cu] Atualização por classe:180307
[Lr] Data última revisão:
180307
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180301
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000009874


  2 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29173136
[Au] Autor:Bai T; Chen Y; Jiang W; Yan F; Fan Y
[Ad] Endereço:1 Department of Applied Mechanics, Sichuan University, Chengdu, China.
[Ti] Título:Studies on Foam Decay Trend and Influence of Temperature Jump on Foam Stability in Sclerotherapy.
[So] Source:Vasc Endovascular Surg;52(2):98-106, 2018 Feb.
[Is] ISSN:1938-9116
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:OBJECTIVES: This study investigated the influence of temperature jump and liquid-gas ratio on foam stability to derive the foam-decay law. METHODS: The experimental group conditions were as follows: mutation temperatures (10°C, 16°C, 20°C, 23°C, 25°C, and 27°C to >37°C) and liquid-gas ratios (1:1, 1:2, 1:3, and 1:4). The control group conditions were as follows: temperatures (10°C, 16°C, 20°C, 23°C, 25°C and 27°C) and liquid-gas ratios (1:1, 1:2, 1:3, and 1:4). A homemade device manufactured using the Tessari DSS method was used to prepare the foam. The decay process was videotape recorded. In the drainage rate curve, the temperature rose, and the liquid-gas ratio varied from 1:1 to 1:4, causing faster decay. RESULTS: In the entire process, the foam volume decreased with increasing drainage rate. The relationships were almost linear. Comparison of the experimental and control groups shows that the temperature jump results in a drainage time range of 1 to 15 seconds. The half-life ranges from 10 to 30 seconds. The maximum rate is 18.85%. Changes in the preparation temperature yields a drainage time range of 3 to 30 seconds. The half-life varies from 20 to 60 seconds. CONCLUSION: Decreasing the temperature jump range and liquid-gas ratio gradually enhances the foam stability. The foam decay time and drainage rate exhibit an exponential function distribution.
[Mh] Termos MeSH primário: Soluções Esclerosantes/química
Escleroterapia/métodos
Morruato de Sódio/química
Temperatura Ambiente
[Mh] Termos MeSH secundário: Estabilidade de Medicamentos
Meia-Vida
Modelos Lineares
Modelos Químicos
Transição de Fase
Fatores de Tempo
Gravação em Vídeo
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Sclerosing Solutions); 8031-09-2 (Sodium Morrhuate)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180228
[Lr] Data última revisão:
180228
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171128
[St] Status:MEDLINE
[do] DOI:10.1177/1538574417741786


  3 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29311469
[Au] Autor:Takai Y; Hiramoto K; Nishimura Y; Ooi K
[Ad] Endereço:Department of Pharmacy, Mie Heart Center Hospital.
[Ti] Título:[Sex Differences of the Inflammatory Mediator Level at the Time of Itch Onset in Patients with Chronic Venous Disease].
[So] Source:Yakugaku Zasshi;138(1):91-96, 2018.
[Is] ISSN:1347-5231
[Cp] País de publicação:Japan
[La] Idioma:jpn
[Ab] Resumo:This study investigated the sex differences of the inflammatory mediator level at the time of itch onset in patients with chronic venous disease (CVD). Twenty-seven CVD patients (nineteen women, eight men) and nine healthy controls (five women, four men) participated. CVD-associated itching was observed in both men and women. Before sclerotherapy, both sexes had elevations in several itch-related mediators. Among these, women had significantly higher tryptase, whereas men had significantly higher ß-endorphin and adrenocorticotropic hormone. After sclerotherapy, all levels normalized in both sexes. In this study, itching was increased tryptase in women and increased adrenocorticotropic hormone and ß-endorphin in men.
[Mh] Termos MeSH primário: Hormônio Adrenocorticotrópico/metabolismo
Mediadores da Inflamação/metabolismo
Prurido/fisiopatologia
Caracteres Sexuais
Triptases/metabolismo
Doenças Vasculares/metabolismo
Doenças Vasculares/fisiopatologia
beta-Endorfina/metabolismo
[Mh] Termos MeSH secundário: Adulto
Idoso
Doença Crônica
Feminino
Seres Humanos
Masculino
Meia-Idade
Escleroterapia
Doenças Vasculares/terapia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Inflammation Mediators); 60617-12-1 (beta-Endorphin); 9002-60-2 (Adrenocorticotropic Hormone); EC 3.4.21.59 (Tryptases)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180226
[Lr] Data última revisão:
180226
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:180110
[St] Status:MEDLINE
[do] DOI:10.1248/yakushi.17-00160


  4 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29381910
[Au] Autor:Lihua J; Feng G; Shanshan M; Jialu X; Kewen J
[Ad] Endereço:Department of Pediatric Neurology, the Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
[Ti] Título:Somatic KRAS mutation in an infant with linear nevus sebaceous syndrome associated with lymphatic malformations: A case report and literature review.
[So] Source:Medicine (Baltimore);96(47):e8016, 2017 Nov.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:RATIONALE: Linear nevus sebaceous syndrome (LNSS) is a rare neurocutaneous syndrome, characterized by nevus sebaceous,central nervous system (CNS), ocular and skeletal abnormalities. The present study describes KRAS somatic mosaic mutation in a case of LNSS with lymphatic malformations (LMs). PATIENT CONCERNS: A 4-month-old female with a clinical diagnosis of LNSS presented with infantile spasms, mental retardation, skull dysplasia, ocular abnormalities, congenital atrial septal defect, and LMs. DIAGNOSIS: Cervical ultrasonography revealed a 4.6 × 4.6 × 2.2cm no echo packet with clear boundary in the subcutaneous tissues of the right neck. The neck MRI indicated a cyst in the subcutaneous tissues of the right neck. Whole-exome sequencing revealed a low-level heterozygous mutation of the KRAS gene (c.35C > T; p.G12D, 19%) in the skin lesion sample. This mutation was not present in the blood samples of the patient and her parents. INTERVENTIONS: The patient received sclerotherapy with paicibanil (OK-432) injection for the cyst. OUTCOMES: Following 1 year of treatment, the patient exhibited fewer seizures. The mental and motor development was significantly improved. The patient can currently walk with assistance and speak simple words. LESSONS: LNSS is a rare, congenital neurocutaneous syndrome consisting of a spectrum of abnormalities involving the skin, central nervous system, eyes, LMs and other systems. LNSS can be caused by postzygotic somatic mutation in the RAS family of genes. Multidisciplinary evaluation and treatment is needed.
[Mh] Termos MeSH primário: Nevo Sebáceo de Jadassohn/genética
Nevo Sebáceo de Jadassohn/patologia
[Mh] Termos MeSH secundário: Antineoplásicos/uso terapêutico
Feminino
Seres Humanos
Lactente
Nevo Sebáceo de Jadassohn/diagnóstico
Nevo Sebáceo de Jadassohn/terapia
Picibanil/uso terapêutico
Escleroterapia/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antineoplastic Agents); 39325-01-4 (Picibanil)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180220
[Lr] Data última revisão:
180220
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:180201
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000008016


  5 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28746255
[Au] Autor:Hirabayashi KE; Kalin-Hajdu E; Bever GJ; Vagefi MR; de Alba Campomanes AG; Cooke DL; Dowd CF; Kersten RC
[Ti] Título:Normalization of Congenital Venous Stasis Retinopathy Following Sclerotherapy of a Macrocystic Lymphatic Malformation.
[So] Source:Ophthal Plast Reconstr Surg;34(1):e19-e21, 2018 Jan/Feb.
[Is] ISSN:1537-2677
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:The authors describe, for the first time to their knowledge, a case of a congenital macrocystic lymphatic malformation of the orbit with associated venous stasis retinopathy that acutely normalized after drainage and sclerotherapy of the lesion. Prenatal ultrasound revealed prominence of the left orbital soft tissue, and at birth, the patient was noted to have unilateral proptosis, tortuous retinal vessels, and intraretinal hemorrhages in all 4 quadrants in the left eye. MRI demonstrated a primarily intraconal, multiloculated, T2-hyperintense mass consistent with a lymphatic malformation. Ultrasound-guided cyst aspiration and sclerotherapy was performed, with subsequent improvement of the proptosis and resolution of the vessel tortuosity and intraretinal hemorrhages. Although venous stasis retinopathy is usually related to central retinal vein occlusion or carotid artery occlusive disease, any entity that increases orbital venous resistance can generate retinal venous dilation and intraretinal hemorrhages, including an orbital lymphatic malformation.
[Mh] Termos MeSH primário: Anormalidades Linfáticas/tratamento farmacológico
Doenças Orbitárias/tratamento farmacológico
Recuperação de Função Fisiológica
Doenças Retinianas/induzido quimicamente
Veia Retiniana/fisiopatologia
Soluções Esclerosantes/efeitos adversos
Escleroterapia/efeitos adversos
[Mh] Termos MeSH secundário: Dexametasona/administração & dosagem
Feminino
Seguimentos
Glucocorticoides/administração & dosagem
Seres Humanos
Recém-Nascido
Injeções Intravenosas
Anormalidades Linfáticas/diagnóstico
Anormalidades Linfáticas/cirurgia
Imagem por Ressonância Magnética
Doenças Orbitárias/congênito
Doenças Orbitárias/cirurgia
Paracentese/métodos
Fluxo Sanguíneo Regional/fisiologia
Doenças Retinianas/diagnóstico
Doenças Retinianas/tratamento farmacológico
Cirurgia Assistida por Computador/métodos
[Pt] Tipo de publicação:CASE REPORTS; JOURNAL ARTICLE; RESEARCH SUPPORT, NON-U.S. GOV'T
[Nm] Nome de substância:
0 (Glucocorticoids); 0 (Sclerosing Solutions); 7S5I7G3JQL (Dexamethasone)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180219
[Lr] Data última revisão:
180219
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170727
[St] Status:MEDLINE
[do] DOI:10.1097/IOP.0000000000000975


  6 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28466660
[Au] Autor:Gong X; Zhou Q; Chen S; Wang F; Wu W; Chen X
[Ad] Endereço:a Department of Endocrinology and Metabolism , the First Affiliated Hospital of Wenzhou Medical University , Ouhai District , Wenzhou 325015 , Zhejiang Province , PR China.
[Ti] Título:Efficacy and safety of ultrasound-guided percutaneous polidocanol sclerotherapy in benign predominantly cystic thyroid nodules: a prospective study.
[So] Source:Curr Med Res Opin;33(8):1505-1510, 2017 Aug.
[Is] ISSN:1473-4877
[Cp] País de publicação:England
[La] Idioma:eng
[Ab] Resumo:OBJECTIVE: To evaluate the efficacy and safety of percutaneous polidocanol injection (PPI) in treatment of predominantly cystic thyroid nodules. MATERIALS AND METHODS: This prospective study included 111 patients with 122 benign predominantly cystic thyroid nodules inducing pressure symptoms or cosmetic problems. The nodules were randomized to a single aspiration with (n = 61) or without (n = 61) subsequent PPI and followed up after 1, 3, 6, and 12 months. Ten patients (12 nodules) declined to follow up after aspiration in group 2. Nodule volumes, symptoms scores, and cosmetic scores were evaluated before and after treatment. The therapeutic success rate and safety of PPI for treatment of predominantly cystic thyroid nodules were also evaluated. RESULTS: In the PPI group, the nodule volumes were reduced from 13.67 ± 9.90 to 2.60 ± 2.66 (p < .001). Therapeutic success rate (nodule volume reduction >50%) was obtained in 57 of 61 (93.44%) nodules in the PPI group, compared to seven of 49 (14.29%) in the aspiration group (p < .001). In the aspiration group, the nodule volume was not significantly reduced. The reduction in symptom scores was significantly higher in the PPI group (from 3.60 ± 1.65 to 1.60 ± 1.19) than in the aspiration group (from 3.62 ± 1.89 to 3.30 ± 1.06) (p < .001, between groups). The reduction in cosmetic scores showed a significant difference between groups (p < .001). In total, 4.92% of patients (3/61) in the PPI group and 85.71% (42/49) in the aspiration group showed recurrence during the follow-up period. There was a significant difference in the recurrence rate between groups (p < .001). No major side-effects occurred. CONCLUSIONS: US-guided PPI of benign recurrent predominantly cystic thyroid nodules is effective and safe. PPI is an important alternative to benign recurrent predominantly cystic thyroid nodules.
[Mh] Termos MeSH primário: Polietilenoglicóis/administração & dosagem
Escleroterapia/métodos
Nódulo da Glândula Tireoide/terapia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idoso
Feminino
Seguimentos
Seres Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Recidiva
Resultado do Tratamento
Adulto Jovem
[Pt] Tipo de publicação:COMPARATIVE STUDY; JOURNAL ARTICLE; RANDOMIZED CONTROLLED TRIAL
[Nm] Nome de substância:
0AWH8BFG9A (polidocanol); 30IQX730WE (Polyethylene Glycols)
[Em] Mês de entrada:1802
[Cu] Atualização por classe:180213
[Lr] Data última revisão:
180213
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170504
[St] Status:MEDLINE
[do] DOI:10.1080/03007995.2017.1325732


  7 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
[PMID]:29243898
[Au] Autor:Saarinen J
[Ti] Título:Invasive treatment of superficial veins of the lower extremities.
[So] Source:Duodecim;133(11):1069-75, 2017.
[Is] ISSN:0012-7183
[Cp] País de publicação:Finland
[La] Idioma:eng
[Ab] Resumo:Modern invasive treatment of superficial venous insufficiency of the lower extremities is largely based on the use of intravenous procedures under ultrasound guidance. The first-line treatment is thermoablation, in which the insufficient superficial vein, typically vena saphena magna or parva, is constricted by using laser or radio frequency energy under ultrasound guidance. The procedure is nearly always successful under local anesthesia and can be performed as an outpatient operation. When necessary, visible collateral varices can be treated with foam sclerotherapy or by surgical excision. The need for associated medication or longer follow-up is limited and recovery is fast. The patients can be mobilized immediately, and only a couple of days of sick leave are usually required.
[Mh] Termos MeSH primário: Perna (Membro)/irrigação sanguínea
Insuficiência Venosa/cirurgia
[Mh] Termos MeSH secundário: Técnicas de Ablação
Deambulação Precoce
Seres Humanos
Fluxo Sanguíneo Regional
Escleroterapia
Ultrassonografia de Intervenção
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1801
[Cu] Atualização por classe:180115
[Lr] Data última revisão:
180115
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171216
[St] Status:MEDLINE


  8 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:29078866
[Au] Autor:López JJ; Lodwick DL; Cooper JN; Hogan M; King D; Minneci PC
[Ad] Endereço:Center for Surgical Outcomes Research, Nationwide Children's Hospital, Columbus, Ohio; Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, Ohio.
[Ti] Título:Sclerotherapy for splenic cysts in children.
[So] Source:J Surg Res;219:1-4, 2017 Nov.
[Is] ISSN:1095-8673
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:BACKGROUND: Sclerotherapy has been described as a treatment option for nonparasitic pediatric splenic cysts; however, there are limited data on its long-term effectiveness. METHODS: We performed a retrospective review and prospective follow-up imaging study of children treated for nonparasitic splenic cysts at our institution during 2006-2015. Included patients had International Classification of Disease, Ninth Revision, Clinical Modification diagnosis code 289.59 or 759.0 and underwent either sclerotherapy or a partial splenic operation (partial splenectomy, cyst excision, or marsupialization). Charts were reviewed for demographics, imaging, treatments, and complications. Identified patients were contacted and asked to return for splenic ultrasonography. RESULTS: Six surgical patients and 19 sclerotherapy patients were identified. Sclerotherapy patients underwent a median of four treatments with a decrease in the size of the cyst or complete ablation in 89.5% (17/19). Of the two patients who underwent unsuccessful sclerotherapy, one patient had sclerotherapy with sotradecol and ethanol for eight treatments, developed infection, and underwent total splenectomy. The other patient did not improve with sclerotherapy and underwent partial splenectomy. Nine patients (eight patients treated with sclerotherapy and one patient treated with partial splenectomy) were successfully contacted and underwent follow-up imaging at a median follow-up of 2.4 y since last treatment. Of the eight patients treated with sclerotherapy, four patients remained cyst-free, three had small residual asymptomatic cysts stable in size, and one developed a recurrent small asymptomatic cyst; the patient treated with surgery had no recurrence. CONCLUSIONS: Sclerotherapy appears to be an effective and durable alternative treatment for children with splenic cysts.
[Mh] Termos MeSH primário: Cistos/terapia
Escleroterapia
Esplenopatias/terapia
[Mh] Termos MeSH secundário: Adolescente
Criança
Cistos/diagnóstico por imagem
Feminino
Seguimentos
Seres Humanos
Masculino
Estudos Prospectivos
Recidiva
Estudos Retrospectivos
Esplenectomia
Esplenopatias/diagnóstico por imagem
Resultado do Tratamento
Ultrassonografia
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Em] Mês de entrada:1711
[Cu] Atualização por classe:171109
[Lr] Data última revisão:
171109
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:171029
[St] Status:MEDLINE


  9 / 4879 MEDLINE  
              first record previous record next record last record
seleciona
para imprimir
Fotocópia
Texto completo SciELO Brasil
[PMID]:28954096
[Au] Autor:AlGhamdi KM; Kumar A; Ashour AE; Al-Rikabi AC; AlOmrani AH; Ahamed SS
[Ad] Endereço:Dermatology Department, College of Medicine, King Saud University - Riyadh, Saudi Arabia.
[Ti] Título:Vascular sclerosing effects of bleomycin on cutaneous veins: a pharmacopathologic study on experimental animals.
[So] Source:An Bras Dermatol;92(4):484-491, 2017 Jul-Aug.
[Is] ISSN:1806-4841
[Cp] País de publicação:Brazil
[La] Idioma:eng
[Ab] Resumo:Background:: Varicose veins and the complications of venous disease are common disorders in humans. Objective:: To study the effects of bleomycin as a potential new sclerosing agent and its adverse events in treating varicose veins. Methods:: Bleomycin-loaded liposomes 0.1ml was injected in the dorsal ear veins of white New Zealand rabbits. Sodium tetradecyl sulfate was used as a positive control. Normal saline was used as negative control. The blood vessels of the treated ears were photographed before and at one hour and two, eight and 45 days after treatment. Biopsies from the treated areas were obtained for histological examination. Blood samples were collected to determine any possible toxicity. Results:: Bleomycin by itself was ineffective; therefore, liposomes were used as a vector to deliver bleomycin to the vein lumen. Subsequently, bleomycin started showing its sclerosing effects. Toxicity monitoring showed no apparent hematologic, pulmonary, hepatic or renal toxicities. This study revealed that bleomycin induced vasculitis, which led to vascular occlusion, which was observed on day 1 and day 8. No bleomycin-related injury was noted by histopathological examination of lung sections. The calculation of the lung/body weight coefficient indicated that edema was present in the experimental groups compared with the negative and positive controls. Study limitations:: Relatively small number of experimental animals used. Conclusions:: This study showed that bleomycin-loaded liposomes were able to induce vasculitis and vascular occlusion without any toxicity or complications. It might be useful, hence, to treat patients suffering from Varicose veins and other ectatic vascular diseases with this agent.
[Mh] Termos MeSH primário: Antibióticos Antineoplásicos/administração & dosagem
Bleomicina/farmacologia
Soluções Esclerosantes/farmacologia
Escleroterapia/métodos
Tetradecilsulfato de Sódio/administração & dosagem
Varizes/terapia
[Mh] Termos MeSH secundário: Animais
Bleomicina/administração & dosagem
Modelos Animais de Doenças
Avaliação Pré-Clínica de Medicamentos
Injeções Intravenosas
Lipossomos
Coelhos
Soluções Esclerosantes/administração & dosagem
Soluções Esclerosantes/efeitos adversos
Vasculite/induzido quimicamente
Vasculite/tratamento farmacológico
Veias/efeitos dos fármacos
[Pt] Tipo de publicação:JOURNAL ARTICLE
[Nm] Nome de substância:
0 (Antibiotics, Antineoplastic); 0 (Liposomes); 0 (Sclerosing Solutions); 11056-06-7 (Bleomycin); Q1SUG5KBD6 (Sodium Tetradecyl Sulfate)
[Em] Mês de entrada:1710
[Cu] Atualização por classe:171010
[Lr] Data última revisão:
171010
[Sb] Subgrupo de revista:IM
[Da] Data de entrada para processamento:170928
[St] Status:MEDLINE


  10 / 4879 MEDLINE  
              first record previous record
seleciona
para imprimir
Fotocópia
Texto completo
[PMID]:28834877
[Au] Autor:Hugon-Rodin J; Horellou MH; Conard J; Flaujac C; Gompel A; Plu-Bureau G; and for the COntraception, REcurrent Venous Event (COREVE) investigators
[Ad] Endereço:aUniversity Paris-Saclay and Paris-Sud, UVSQ, CESP, U1018, INSERM, Villejuif bGynecology Endocrinology Unit, Port-Royal Hospital, Paris cUniversity Paris Descartes dHematology Biology Unit, Hôpital Universitaire Paris centre, Paris, France.
[Ti] Título:First venous thromboembolism and hormonal contraceptives in young French women.
[So] Source:Medicine (Baltimore);96(34):e7734, 2017 Aug.
[Is] ISSN:1536-5964
[Cp] País de publicação:United States
[La] Idioma:eng
[Ab] Resumo:Information on the clinical and biological characteristics of combined hormonal contraceptives (CHC) users experiencing a venous thromboembolism (VTE) event is scarce. Better knowledge of factors determining the VTE risk in CHC users could help identify women at high risk.Data were obtained from a large cohort of consecutive women with the first documented VTE event. Cross-sectional analysis of clinical and biological characteristics of the women was performed.Of the 3009 women with the first VTE included, 31% were nonusers and 69% CHC users at time of VTE. CHC users were significantly younger (29.0 ±â€Š7.2) than nonusers (31.6 ±â€Š7.1) (P < .001). No difference in VTE familial history was observed between the 2 groups. Compared with nonusers, the CHC users experienced more frequently pulmonary embolism: odds ratio (OR) = 1.28 (1.06-1.55; 95% confidence interval [CI]), factor V Leiden mutations were more frequent in this group (OR = 1.41 [1.11-1.80; 95% CI]). Venous sclerotherapy and travel were associated with VTE in CHC users, whereas surgery and bed rest were significantly associated with VTE in nonusers. Finally, 2/3 of CHC users with VTE had additional VTE risk factors.CHC users experiencing the first VTE differ from nonusers with respect to clinical and genetic background. Better understanding of the characteristics of VTE and associated risk factors could allow more appropriate management of these women and contribute to more accurate benefit-risk assessment before prescribing a CHC.
[Mh] Termos MeSH primário: Anticoncepcionais Orais Combinados/administração & dosagem
Tromboembolia Venosa/epidemiologia
[Mh] Termos MeSH secundário: Adolescente
Adulto
Idade de Início
Estudos Transversais
Feminino
Seres Humanos
Meia-Idade
Razão de Chances
Medição de Risco
Fatores de Risco
Escleroterapia/estatística & dados numéricos
Procedimentos Cirúrgicos Operatórios/estatística & dados numéricos
Viagem/estatística & dados numéricos
Adulto Jovem
[Pt] Tipo de publicação:JOURNAL ARTICLE; OBSERVATIONAL STUDY
[Nm] Nome de substância:
0 (Contraceptives, Oral, Combined)
[Em] Mês de entrada:1709
[Cu] Atualização por classe:170911
[Lr] Data última revisão:
170911
[Sb] Subgrupo de revista:AIM; IM
[Da] Data de entrada para processamento:170824
[St] Status:MEDLINE
[do] DOI:10.1097/MD.0000000000007734



página 1 de 488 ir para página                         
   


Refinar a pesquisa
  Base de dados : MEDLINE Formulário avançado   

    Pesquisar no campo  
1  
2
3
 
           



Search engine: iAH v2.6 powered by WWWISIS

BIREME/OPAS/OMS - Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde